id category name description provided_by BFO:0000004 biolink:NamedThing independent continuant b is an independent continuant = Def. b is a continuant which is such that there is no c and no t such that b s-depends_on c at t. (axiom label in BFO2 Reference: [017-002]) FYPO_relaxed.owl BFO:0000002 biolink:NamedThing continuant An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. FYPO_relaxed.owl BFO:0000020 biolink:NamedThing specifically dependent continuant b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) FYPO_relaxed.owl BFO:0000031 biolink:NamedThing generically dependent continuant b is a generically dependent continuant = Def. b is a continuant that g-depends_on one or more other entities. (axiom label in BFO2 Reference: [074-001]) FYPO_relaxed.owl FYPO:0006508 biolink:NamedThing abnormal telomere morphology A physical cellular phenotype in which the size, shape, or structure of the telomere is abnormal. FYPO_relaxed.owl FYPO:0006592 biolink:NamedThing monopolar mitotic spindle nucleated from old spindle pole body A physical cellular phenotype in which the mitotic spindle forms with microtubules emanating from only one pole, nucleated from the old spindle pole body. FYPO_relaxed.owl BFO:0000006 biolink:NamedThing spatial region FYPO_relaxed.owl BFO:0000141 biolink:NamedThing immaterial entity FYPO_relaxed.owl BFO:0000015 biolink:NamedThing process p is a process = Def. p is an occurrent that has temporal proper parts and for some time t, p s-depends_on some material entity at t. (axiom label in BFO2 Reference: [083-003]) FYPO_relaxed.owl BFO:0000003 biolink:NamedThing occurrent An entity that has temporal parts and that happens, unfolds or develops through time. FYPO_relaxed.owl GO:0000752 biolink:NamedThing agglutination involved in conjugation with cellular fusion The aggregation or adhesion of compatible mating types via complementary cell-cell interactions during conjugation with cellular fusion of a unicellular organism. An example of this process is agglutination in Saccharomyces cerevisiae. FYPO_relaxed.owl GO:0000959 biolink:NamedThing mitochondrial RNA metabolic process The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion. FYPO_relaxed.owl GO:0001054 biolink:NamedThing RNA polymerase I activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase I specific promoter to direct initiation and catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. FYPO_relaxed.owl GO:0001055 biolink:NamedThing RNA polymerase II activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. FYPO_relaxed.owl GO:0001056 biolink:NamedThing RNA polymerase III activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'. FYPO_relaxed.owl GO:0006120 biolink:NamedThing mitochondrial electron transport, NADH to ubiquinone The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation. FYPO_relaxed.owl GO:0006121 biolink:NamedThing mitochondrial electron transport, succinate to ubiquinone The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II. FYPO_relaxed.owl GO:0006267 biolink:NamedThing pre-replicative complex assembly involved in nuclear cell cycle DNA replication The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation. FYPO_relaxed.owl GO:0006624 biolink:NamedThing vacuolar protein processing Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes. FYPO_relaxed.owl GO:0007006 biolink:NamedThing mitochondrial membrane organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion. FYPO_relaxed.owl GO:0007039 biolink:NamedThing protein catabolic process in the vacuole The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases. FYPO_relaxed.owl GO:0007127 biolink:NamedThing meiosis I The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei. FYPO_relaxed.owl GO:0009882 biolink:NamedThing blue light photoreceptor activity The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation. FYPO_relaxed.owl GO:0010938 biolink:NamedThing cytoplasmic microtubule depolymerization The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule. FYPO_relaxed.owl GO:0019093 biolink:NamedThing mitochondrial RNA localization Any process in which mitochondrial RNA is transported to, or maintained in, a specific location. FYPO_relaxed.owl GO:0023061 biolink:NamedThing signal release The process in which a signal is secreted or discharged into the extracellular medium from a cellular source. FYPO_relaxed.owl GO:0031087 biolink:NamedThing deadenylation-independent decapping of nuclear-transcribed mRNA Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening. FYPO_relaxed.owl GO:0032042 biolink:NamedThing mitochondrial DNA metabolic process The chemical reactions and pathways involving mitochondrial DNA. FYPO_relaxed.owl GO:0032065 biolink:NamedThing maintenance of protein location in cell cortex A process in which a protein or protein complex is maintained in a specific location in the cell cortex. FYPO_relaxed.owl GO:0032118 biolink:NamedThing horsetail-astral microtubule organization A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis. FYPO_relaxed.owl GO:0032543 biolink:NamedThing mitochondrial translation The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code. FYPO_relaxed.owl GO:0033260 biolink:NamedThing nuclear DNA replication The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle. FYPO_relaxed.owl GO:0033617 biolink:NamedThing mitochondrial cytochrome c oxidase assembly The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane. FYPO_relaxed.owl GO:0034551 biolink:NamedThing mitochondrial respiratory chain complex III assembly The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane. FYPO_relaxed.owl GO:0034982 biolink:NamedThing mitochondrial protein processing The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import. FYPO_relaxed.owl GO:0035694 biolink:NamedThing mitochondrial protein catabolic process The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure. FYPO_relaxed.owl GO:0036402 biolink:NamedThing proteasome-activating activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome. FYPO_relaxed.owl GO:0042774 biolink:NamedThing plasma membrane ATP synthesis coupled electron transport The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane. FYPO_relaxed.owl GO:0042775 biolink:NamedThing mitochondrial ATP synthesis coupled electron transport The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane. FYPO_relaxed.owl GO:0042776 biolink:NamedThing proton motive force-driven mitochondrial ATP synthesis The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis. FYPO_relaxed.owl GO:0043162 biolink:NamedThing ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. FYPO_relaxed.owl GO:0046907 biolink:NamedThing intracellular transport The directed movement of substances within a cell. FYPO_relaxed.owl GO:0061804 biolink:NamedThing mitotic spindle formation (spindle phase one) The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase. FYPO_relaxed.owl GO:0061805 biolink:NamedThing mitotic spindle elongation (spindle phase three) The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B. FYPO_relaxed.owl GO:0070124 biolink:NamedThing mitochondrial translational initiation The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA. FYPO_relaxed.owl GO:0070125 biolink:NamedThing mitochondrial translational elongation The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion. FYPO_relaxed.owl GO:0070918 biolink:NamedThing regulatory ncRNA processing A process leading to the generation of a functional regulatory non-coding RNA. FYPO_relaxed.owl GO:0071163 biolink:NamedThing DNA replication preinitiation complex assembly The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at DNA replication origins as part of initiation of DNA replication. The complex consists of proteins that initiate the DNA binding, melt the helix and enable helicase activity. FYPO_relaxed.owl GO:0072595 biolink:NamedThing maintenance of protein localization in organelle Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. FYPO_relaxed.owl GO:0090139 biolink:NamedThing mitochondrial chromosome packaging A process in which mitochondrial chromosomal DNA and associated proteins organize into a compact, orderly structure. FYPO_relaxed.owl GO:0097472 biolink:NamedThing cyclin-dependent protein kinase activity Cyclin-dependent catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. FYPO_relaxed.owl GO:0098762 biolink:NamedThing meiotic cell cycle phase One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. FYPO_relaxed.owl GO:0098763 biolink:NamedThing mitotic cell cycle phase One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. FYPO_relaxed.owl GO:0099017 biolink:NamedThing maintenance of protein localization at cell tip Any process in which localization of a protein is maintained at the cell tip. FYPO_relaxed.owl GO:0120113 biolink:NamedThing cytoplasm to vacuole transport by the NVT pathway A pathway targeting soluble cytosolic proteins to the vacuole lumen. It uses a selective autophagy receptor protein Nbr1, which is an ortholog of mammalian NBR1, and is remotely related to S. cerevisiae Cvt pathway receptor protein Atg19. Similar to the Cvt pathway, the cargos transported by this pathway are hydrolases, which presumably contribute to the hydrolytic activities in the vacuole lumen. Different from the Cvt pathway, this pathway does not require the macroautophagy machinery, but instead relies on the ESCRT machinery for cargo sequestration. This pathway is observed in the fission yeast S. pombe. FYPO_relaxed.owl GO:0140053 biolink:NamedThing mitochondrial gene expression The process in which a mitochondrial gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA or circRNA (for protein-coding genes) and the translation of that mRNA or circRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form. FYPO_relaxed.owl GO:0140142 biolink:NamedThing nucleocytoplasmic carrier activity Binding to and carrying a cargo between the nucleus and the cytoplasm by moving along with the cargo. The cargo can be either a RNA or a protein. FYPO_relaxed.owl GO:0140405 biolink:NamedThing spindle pole body-led chromosome movement during mitotic interphase A microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase. FYPO_relaxed.owl GO:0140994 biolink:NamedThing RNA polymerase II CTD heptapeptide repeat modifying activity A catalytic activity that acts on the RNA polymerase II large subunit CTD heptapeptide repeat (consensus YSPTSPS). Reversible modifications cof the RNA polymerase II CTD repeats contribute to regulation of RNA polymerase activity. FYPO_relaxed.owl GO:1902315 biolink:NamedThing nuclear cell cycle DNA replication initiation Any DNA replication initiation that is involved in nuclear cell cycle DNA replication. FYPO_relaxed.owl GO:1902317 biolink:NamedThing nuclear DNA replication termination Any DNA replication termination that is involved in nuclear cell cycle DNA replication. FYPO_relaxed.owl GO:1902318 biolink:NamedThing synthesis of RNA primer involved in nuclear cell cycle DNA replication Any synthesis of RNA primer that is involved in nuclear cell cycle DNA replication. FYPO_relaxed.owl GO:1902319 biolink:NamedThing DNA strand elongation involved in nuclear cell cycle DNA replication Any DNA strand elongation that is involved in nuclear cell cycle DNA replication. FYPO_relaxed.owl GO:1902320 biolink:NamedThing nuclear DNA replication DNA duplex unwinding Any DNA duplex unwinding that is involved in nuclear cell cycle DNA replication. FYPO_relaxed.owl GO:1903469 biolink:NamedThing removal of RNA primer involved in mitotic DNA replication Any DNA replication, removal of RNA primer that is involved in mitotic cell cycle DNA replication. FYPO_relaxed.owl GO:1903563 biolink:NamedThing microtubule bundle formation involved in horsetail-astral microtubule organization Any microtubule bundle formation that is involved in horsetail-astral microtubule organization. FYPO_relaxed.owl GO:1904860 biolink:NamedThing DNA synthesis involved in mitotic DNA replication Any DNA biosynthetic process that is involved in mitotic DNA replication. FYPO_relaxed.owl GO:1990505 biolink:NamedThing mitotic DNA replication maintenance of fidelity Any maintenance of fidelity that is involved in mitotic cell cycle DNA replication. FYPO_relaxed.owl BFO:0000016 biolink:NamedThing disposition FYPO_relaxed.owl BFO:0000017 biolink:NamedThing realizable entity A specifically dependent continuant that inheres in continuant entities and are not exhibited in full at every time in which it inheres in an entity or group of entities. The exhibition or actualization of a realizable entity is a particular manifestation, functioning or process that occurs under certain circumstances. FYPO_relaxed.owl BFO:0000023 biolink:NamedThing role A realizable entity the manifestation of which brings about some result or end that is not essential to a continuant in virtue of the kind of thing that it is but that can be served or participated in by that kind of continuant in some kinds of natural, social or institutional contexts. FYPO_relaxed.owl BFO:0000019 biolink:NamedThing quality FYPO_relaxed.owl FYPO:0000710 biolink:NamedThing abnormal mitotic cell cycle arrest in response to nitrogen starvation A cellular process phenotype in which mitotic cell cycle arrest in response to nitrogen starvation, which normally occurs in G1 phase, is abnormal. FYPO_relaxed.owl BFO:0000030 biolink:NamedThing object FYPO_relaxed.owl BFO:0000040 biolink:NamedThing material entity An independent continuant that is spatially extended whose identity is independent of that of other entities and can be maintained through time. FYPO_relaxed.owl CL:0000151 biolink:NamedThing secretory cell A cell that specializes in controlled release of one or more substances. FYPO_relaxed.owl CL:0011115 biolink:NamedThing precursor cell A cell that, by division or terminal differentiation, can give rise to other cell types. FYPO_relaxed.owl PR:000050567 biolink:NamedThing protein-containing material entity A material entity that minimally consists of a protein. FYPO_relaxed.owl BFO:0000034 biolink:NamedThing function FYPO_relaxed.owl BTO:0000001 biolink:NamedThing culture condition:-induced cell FYPO_relaxed.owl BTO:0000216 biolink:NamedThing culture condition FYPO_relaxed.owl BTO:0001479 biolink:NamedThing culture condition:-grown cell FYPO_relaxed.owl BTO:0000002 biolink:NamedThing culture condition:1,4-dichlorobenzene-grown cell FYPO_relaxed.owl BTO:0000214 biolink:NamedThing cell culture Cells taken from a living organism and grown under controlled conditions (in culture). Methods used to maintain cell lines or strains. FYPO_relaxed.owl BTO:0001490 biolink:NamedThing other source Other sources of an enzyme as cell culture or commercial preparation, not related to a specific tissue. FYPO_relaxed.owl BTO:0000000 biolink:NamedThing tissues, cell types and enzyme sources A structured controlled vocabulary for the source of an enzyme. It comprises terms of tissues, cell lines, cell types and cell cultures from uni- and multicellular organisms. FYPO_relaxed.owl CHEBI:100147 biolink:NamedThing nalidixic acid A monocarboxylic acid comprising 1,8-naphthyridin-4-one substituted by carboxylic acid, ethyl and methyl groups at positions 3, 1, and 7, respectively. An orally administered antibacterial, it is used in the treatment of lower urinary-tract infections due to Gram-negative bacteria, including the majority of E. coli, Enterobacter, Klebsiella, and Proteus species. FYPO_relaxed.owl CHEBI:25384 biolink:NamedThing monocarboxylic acid An oxoacid containing a single carboxy group. FYPO_relaxed.owl CHEBI:15366 biolink:NamedThing acetic acid A simple monocarboxylic acid containing two carbons. FYPO_relaxed.owl CHEBI:168396 biolink:NamedThing mycophenolic acid A member of the class of 2-benzofurans that is 2-benzofuran-1(3H)-one which is substituted at positions 4, 5, 6, and 7 by methyl, methoxy, (2E)-5-carboxy-3-methylpent-2-en-1-yl, and hydroxy groups, respectively. It is an antibiotic produced by Penicillium brevi-compactum, P. stoloniferum, P. echinulatum and related species. An immunosuppressant, it is widely used (partiularly as its sodium salt and as the 2-(morpholin-4-yl)ethyl ester prodrug, mycophenolate mofetil) to prevent tissue rejection following organ transplants and for the treatment of certain autoimmune diseases. FYPO_relaxed.owl CHEBI:22301 biolink:NamedThing aldonic acid Any carbohydrate acid formed by oxidising the aldehyde functional group of an aldose to a carboxylic acid functional group. Aldonic acids have the general formula HOCH2[CH(OH)]nC(=O)OH. FYPO_relaxed.owl CHEBI:26420 biolink:NamedThing pyridinemonocarboxylic acid A monocarboxylic acid in which the carboxy group is attached to a pyridine (or substituted pyridine) ring. FYPO_relaxed.owl CHEBI:26447 biolink:NamedThing pyrimidinemonocarboxylic acid FYPO_relaxed.owl CHEBI:27617 biolink:NamedThing monensin A A spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by Streptomyces cinnamonensis. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle. FYPO_relaxed.owl CHEBI:30751 biolink:NamedThing formic acid The simplest carboxylic acid, containing a single carbon. Occurs naturally in various sources including the venom of bee and ant stings, and is a useful organic synthetic reagent. Principally used as a preservative and antibacterial agent in livestock feed. Induces severe metabolic acidosis and ocular injury in human subjects. FYPO_relaxed.owl CHEBI:35366 biolink:NamedThing fatty acid Any aliphatic monocarboxylic acid derived from or contained in esterified form in an animal or vegetable fat, oil or wax. Natural fatty acids commonly have a chain of 4 to 28 carbons (usually unbranched and even-numbered), which may be saturated or unsaturated. By extension, the term is sometimes used to embrace all acyclic aliphatic carboxylic acids. FYPO_relaxed.owl CHEBI:35868 biolink:NamedThing hydroxy monocarboxylic acid Any monocarboxylic acid which also contains a separate (alcoholic or phenolic) hydroxy substituent. FYPO_relaxed.owl CHEBI:35871 biolink:NamedThing oxo monocarboxylic acid Any monocarboxylic acid having at least one additional oxo functional group. FYPO_relaxed.owl CHEBI:44897 biolink:NamedThing phosphoenolpyruvic acid A monocarboxylic acid that is acrylic acid substituted by a phosphonooxy group at position 2. It is a metabolic intermediate in pathways like glycolysis and gluconeogenesis. FYPO_relaxed.owl CHEBI:51570 biolink:NamedThing biotins Compounds containing a biotin (5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid) skeleton. FYPO_relaxed.owl CHEBI:61747 biolink:NamedThing 4,6-O-[(1R)-1-carboxyethylidene]-D-galactose A monosaccharide derivative consisting of D-galactose having a 1-carboxyethylidene group masking the 4-and 6-positions. FYPO_relaxed.owl CHEBI:79020 biolink:NamedThing alpha,beta-unsaturated monocarboxylic acid A monocarboxylic acid in which the carbon of the carboxy group is directly attached to a C=C or C#C bond. FYPO_relaxed.owl CHEBI:73537 biolink:NamedThing 1,8-naphthyridine derivative Any naphthyridine derivative that is a derivative of 1,8-naphthyridine. FYPO_relaxed.owl CHEBI:86324 biolink:NamedThing quinolone antibiotic An organonitrogen heterocyclic antibiotic whose structure contains a quinolone or quinolone-related skeleton. FYPO_relaxed.owl CHEBI:10106 biolink:NamedThing zearalenone A macrolide comprising a fourteen-membered lactone fused to 1,3-dihydroxybenzene; a potent estrogenic metabolite produced by some Giberella species. FYPO_relaxed.owl CHEBI:25106 biolink:NamedThing macrolide A macrocyclic lactone with a ring of twelve or more members derived from a polyketide. FYPO_relaxed.owl CHEBI:145555 biolink:NamedThing macropolylide Macrolides (macrocyclic lactones) in which the macrocyclic ring contains more than one ester linkage. Macropolylides include macrodiolides, macrotriolides, macrotetrolides and macropentolides, each containing di-, tri-, tetra-, and penta- ester linkages, respectively, in one macrocyclic ring. Macrocyclic lactones containing nitrogen in their skeletons (azamacrolides and macrolide lactams) and also containing oxazole or thiazole in their skeletons are known in nature. FYPO_relaxed.owl CHEBI:145565 biolink:NamedThing macrolide lactam A macrolide in which the macrocyclic lactone ring includes an amide group. FYPO_relaxed.owl CHEBI:23955 biolink:NamedThing erythronolide FYPO_relaxed.owl CHEBI:25105 biolink:NamedThing macrolide antibiotic A macrocyclic lactone with a ring of twelve or more members which exhibits antibiotic activity. FYPO_relaxed.owl CHEBI:49703 biolink:NamedThing latrunculin B A macrolide consisting of a 14-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica. FYPO_relaxed.owl CHEBI:69136 biolink:NamedThing latrunculin A A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes. FYPO_relaxed.owl CHEBI:83267 biolink:NamedThing filipin III A macrolide that is the major component of a mixture of four isomeric polyene macrolides isolated from Streptomyces filipinensis. FYPO_relaxed.owl CHEBI:83275 biolink:NamedThing hypothemycin A macrolide that is isolated from the cultured broth of Hypomyces subiculosus and shows antifungal activity and inhibits the growth of some human cancer cells. FYPO_relaxed.owl CHEBI:33572 biolink:NamedThing resorcinols Any benzenediol in which the two hydroxy groups are meta to one another. FYPO_relaxed.owl CHEBI:32807 biolink:NamedThing o-orsellinic acid A dihydroxybenzoic acid that is 2,4-dihydroxybenzoic acid in which the hydrogen at position 6 is replaced by a methyl group. FYPO_relaxed.owl CHEBI:10334 biolink:NamedThing alpha-terpinene One of three isomeric monoterpenes differing in the positions of their two double bonds (beta- and gamma-terpinene being the others). In alpha-terpinene the double bonds are at the 1- and 3-positions of the p-menthane skeleton. FYPO_relaxed.owl CHEBI:35187 biolink:NamedThing monoterpene A C10 terpene. FYPO_relaxed.owl CHEBI:10577 biolink:NamedThing gamma-terpinene One of three isomeric monoterpenes differing in the positions of their two double bonds (alpha- and beta-terpinene being the others). In gamma-terpinene the double bonds are at the 1- and 4-positions of the p-menthane skeleton. FYPO_relaxed.owl CHEBI:25826 biolink:NamedThing p-menthane FYPO_relaxed.owl CHEBI:28768 biolink:NamedThing p-cymene A monoterpene that is toluene substituted by an isopropyl group at position 4. FYPO_relaxed.owl CHEBI:35783 biolink:NamedThing bornane FYPO_relaxed.owl CHEBI:50073 biolink:NamedThing p-menthadiene A monoterpene that consists of an unsaturated p-menthane skeleton having two double bonds. FYPO_relaxed.owl CHEBI:37613 biolink:NamedThing cyclohexadiene FYPO_relaxed.owl CHEBI:10432 biolink:NamedThing 2-naphthol A naphthol carrying a hydroxy group at position 2. FYPO_relaxed.owl CHEBI:35682 biolink:NamedThing naphthol A member of the class of naphthols carrying a single hydroxy substituent at C-1 or C-2. A closed class. FYPO_relaxed.owl CHEBI:10545 biolink:NamedThing electron Elementary particle not affected by the strong force having a spin 1/2, a negative elementary charge and a rest mass of 0.000548579903(13) u, or 0.51099906(15) MeV. FYPO_relaxed.owl CHEBI:36338 biolink:NamedThing lepton Lepton is a fermion that does not experience the strong force (strong interaction). The term is derived from the Greek lambdaepsilonpitauomicronsigma (small, thin). FYPO_relaxed.owl CHEBI:10642 biolink:NamedThing scyllo-inositol FYPO_relaxed.owl CHEBI:24848 biolink:NamedThing inositol Any cyclohexane-1,2,3,4,5,6-hexol. FYPO_relaxed.owl CHEBI:17268 biolink:NamedThing myo-inositol An inositol having myo- configuration. FYPO_relaxed.owl CHEBI:10986 biolink:NamedThing (R)-4'-phosphonatopantothenate(3-) An organophosphate oxoanion that is the trianion of (R)-5-phosphopantothenic acid arising from deprotonation of the carboxy and phosphate OH groups; major species at pH 7.3 FYPO_relaxed.owl CHEBI:58945 biolink:NamedThing organophosphate oxoanion An organic phosphoric acid derivative in which one or more oxygen atoms of the phosphate group(s) has been deprotonated. FYPO_relaxed.owl CHEBI:175763 biolink:NamedThing 2-trans,6-trans-farnesyl diphosphate(3-) An organophosphate oxoanion that is the trianion obtained by removal of the three protons from the diphosphate group of 2-trans,6-trans-farnesyl diphosphate. FYPO_relaxed.owl CHEBI:176894 biolink:NamedThing vitamin B6 phosphate anion FYPO_relaxed.owl CHEBI:57287 biolink:NamedThing coenzyme A(4-) Tetraanion of coenzyme A. FYPO_relaxed.owl CHEBI:57483 biolink:NamedThing sedoheptulose 7-phosphate(2-) An organophosphate oxoanion that is the dianion of sedoheptulose 7-phosphate arising from deprotonation of both OH groups from the phosphate. FYPO_relaxed.owl CHEBI:57533 biolink:NamedThing geranylgeranyl diphosphate(3-) Trianion of geranylgeranyl diphosphate arising from deprotonation of the three acidic OH groups of the diphosphate. FYPO_relaxed.owl CHEBI:57538 biolink:NamedThing orotidine 5'-phosphate(3-) Trianion of orotidine 5'-phosphate arising from deprotonation of carboxylic acid and phosphate functions. FYPO_relaxed.owl CHEBI:57570 biolink:NamedThing dolichyl diphosphooligosaccharide(2-) The conjugate base of a dolichyl diphosphooligosaccharide. FYPO_relaxed.owl CHEBI:57867 biolink:NamedThing nucleoside 5'-phosphate dianion The conjugate base of a nucleoside 5'-phosphate. FYPO_relaxed.owl CHEBI:57930 biolink:NamedThing nucleoside 5'-diphosphate(3-) Trianion of nucleoside diphosphate arising from deprotonation of all three free OH groups of the diphosphate; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58017 biolink:NamedThing 5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-) Pentaanion of 5-O-phosphono-alpha-D-ribofuranosyl diphosphate arising from deprotonation of the phosphate and diphosphate OH groups; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58043 biolink:NamedThing nucleoside 5'-monophosphate(2-) The dianion of a nucleoside monophosphate: major species at pH 7.3. FYPO_relaxed.owl CHEBI:58141 biolink:NamedThing P(1),P(4)-bis(5'-adenosyl) tetraphosphate(4-) Tetraanion of P(1),P(4)-bis(5'-adenosyl) tetraphosphate arising from deprotonation of the tetraphosphate OH groups; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58165 biolink:NamedThing 3',5'-cyclic AMP(1-) An organophosphate oxoanion that is the conjugate base of 3',5'-cyclic AMP arising from deprotonation of the free phosphate OH group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58369 biolink:NamedThing dTDP(3-) An organophosphate oxoanion arising from deprotonation of the diphosphate OH groups of thymidine 5'-diphosphate; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58429 biolink:NamedThing alpha,alpha-trehalose 6-phosphate(2-) Dianion of alpha,alpha-trehalose 6-phosphate. FYPO_relaxed.owl CHEBI:58443 biolink:NamedThing SAICAR(4-) An organophosphate oxoanion that is the tetraanionic form of SAICAR. It is the major species at pH 7.3. FYPO_relaxed.owl CHEBI:58464 biolink:NamedThing nucleoside 3',5'-cyclic phosphate anion The conjugate base of a nucleoside 3',5'-cyclic phosphate. FYPO_relaxed.owl CHEBI:58475 biolink:NamedThing 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide(2-) An organophosphate oxoanion resulting from the removal of both protons from the phosphate group of 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide. It is the major species at pH 7.3. FYPO_relaxed.owl CHEBI:58702 biolink:NamedThing phosphonatoenolpyruvate An organophosphate oxoanion obtained by deprotonation of the carboxy and phosphate groups of phosphoenolpyruvic acid. FYPO_relaxed.owl CHEBI:58944 biolink:NamedThing dialkyl phosphate anion The conjugate base of a dialkyl phosphate compound FYPO_relaxed.owl CHEBI:58946 biolink:NamedThing acyl-CoA oxoanion Any acyl coenzyme A thioester in which one or more of the phosphate and/or diphosphate groups has been deprotonated. FYPO_relaxed.owl CHEBI:59724 biolink:NamedThing ribonucleoside triphosphate oxoanion An organophosphate anion resulting from deprotonation of at least one of the acidic hydroxy groups from the triphosphate moiety of a nucleoside triphosphate. FYPO_relaxed.owl CHEBI:59737 biolink:NamedThing nucleotide-sugar oxoanion Any nucleotide-sugar in which one or more of the diphosphate OH groups has been deprotonated. FYPO_relaxed.owl CHEBI:61304 biolink:NamedThing phosphoglycerate A glycerate in which at least one of the hydroxy groups has been phosphorylated. FYPO_relaxed.owl CHEBI:61662 biolink:NamedThing 2'-deoxyribonucleoside triphosphate oxoanion An organophosphate anion resulting from deprotonation of at least one of the acidic hydroxy groups from the triphosphate moiety of a 2'-deoxyribonucleoside triphosphate. FYPO_relaxed.owl CHEBI:62643 biolink:NamedThing anionic phospholipid Any organophosphate oxoanion that is a negatively charged phospholipid, e.g. phosphatidylserine(1-), phosphatidate(2-), phosphatidylglycerol(1-). FYPO_relaxed.owl CHEBI:63165 biolink:NamedThing ribonucleoside monophosphate oxoanion An organophosphate oxoanion resulting from deprotonation of at least one of the acidic hydroxy groups from the phosphate moiety of a ribonucleoside monophosphate. FYPO_relaxed.owl CHEBI:63529 biolink:NamedThing guanyl deoxyribonucleotide oxoanion An organophosphate oxoanion that is a guanyl 2'-deoxyribose with one or more deprotonated phosphates on either or both of the 5'- or 3'-hydroxy groups. FYPO_relaxed.owl CHEBI:67140 biolink:NamedThing phosphate monoester dianion Any organphosphate oxoanion resulting from the removal of both protons from the phosphate group of a phosphate monoester. The major species at pH 7.3. FYPO_relaxed.owl CHEBI:73316 biolink:NamedThing 2'-deoxyribonucleoside 5'-diphosphate(3-) An organophosphate oxoanion formed by deprotonation of the diphosphate OH groups of any 2'-deoxynucleoside 5'-diphosphate. FYPO_relaxed.owl CHEBI:76301 biolink:NamedThing inositol phosphate oxoanion Any organophosphate oxoanion derived from an inositol phosphate. FYPO_relaxed.owl CHEBI:87518 biolink:NamedThing ADP(2-) An organophosphate oxoanion obtained by deprotonation of two of the three diphosphate OH groups of adenosine 5'-diphosphate. FYPO_relaxed.owl CHEBI:11230 biolink:NamedThing 1-acylglycerophosphocholine(1+) A glycerophosphocholine having an unspecified O-acyl substituent at the 1-position of the glycerol fragment. FYPO_relaxed.owl CHEBI:60479 biolink:NamedThing lysophosphatidylcholine An acylglycerophosphocholine resulting from partial hydrolysis of a phosphatidylcholine, which removes one of the fatty acyl groups. The structure is depicted in the image where R1 = acyl, R2 = H or where R1 = H, R2 = acyl. FYPO_relaxed.owl CHEBI:11502 biolink:NamedThing 2-acylglycerophosphocholine A glycerophosphocholine having an unspecified acyl group attached at the 2-position. FYPO_relaxed.owl CHEBI:64483 biolink:NamedThing lysophosphatidylcholine 14:0 A lysophosphatidylcholine in which the remaining acyl group is specified as tetradecanoyl (myristoyl). If R1 is the acyl group and R2 is a hydrogen then the molecule is a 1-acyl-sn-glycero-3-phosphocholine. If R1 is a hydrogen and R2 is the acyl group then the molecule is a 2-acyl-sn-glycero-3-phosphocholine. FYPO_relaxed.owl CHEBI:64561 biolink:NamedThing lysophosphatidylcholine 18:0 A lysophosphatidylcholine in which the acyl group has a fully saturated C18 chain and is attached to the glycero moiety at either position 1 or 2. FYPO_relaxed.owl CHEBI:67057 biolink:NamedThing lysophosphatidylcholine 20:1 A lysophosphatidylcholine in which the remaining acyl group contains 20 carbons and 1 double bond. If R1 is the acyl group and R2 is a hydrogen then the molecule is a 1-acyl-sn-glycero-3-phosphocholine. If R1 is a hydrogen and R2 is the acyl group then the molecule is a 2-acyl-sn-glycero-3-phosphocholine. FYPO_relaxed.owl CHEBI:78191 biolink:NamedThing 2-lysophosphatidylcholine Any member of the class of lysophosphatidylcholines which has a free hydroxy group at the 2-position of the glycerol moiety. FYPO_relaxed.owl CHEBI:78192 biolink:NamedThing 1-lysophosphatidylcholine Any member of the class of lysophosphatidylcholines which has a free hydroxy group at the 1-position of the glycerol moiety. FYPO_relaxed.owl CHEBI:84465 biolink:NamedThing acyl-sn-glycero-3-phosphocholine A lysophosphatidylcholine with defined stereochemistry where the position of the acyl group is unknown. FYPO_relaxed.owl CHEBI:116509 biolink:NamedThing diuron A member of the class of 3-(3,4-substituted-phenyl)-1,1-dimethylureas that is urea in which both of the hydrogens attached to one nitrogen are substituted by methyl groups, and one of the hydrogens attached to the other nitrogen is substituted by a 3,4-dichlorophenyl group. FYPO_relaxed.owl CHEBI:157693 biolink:NamedThing 3-(3,4-substituted-phenyl)-1,1-dimethylurea A member of the class of phenylureas that is urea in which one of the nitrogens is substituted by two methyl groups while the other is substituted by a phenyl group which carries two unspecified groups at positions 3 and 4 of the phenyl ring. FYPO_relaxed.owl CHEBI:23697 biolink:NamedThing dichlorobenzene Any member of the class of chlorobenzenes carrying two chloro groups at unspecified positions. FYPO_relaxed.owl CHEBI:48339 biolink:NamedThing 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by imidazol-1-ylmethyl, 2,4-dichlorophenyl, and [para-(4-acetylpiperazin-1-yl)phenoxy]methyl groups, respectively. FYPO_relaxed.owl CHEBI:6076 biolink:NamedThing itraconazole An N-arylpiperazine that is cis-ketoconazole in which the imidazol-1-yl group is replaced by a 1,2,4-triazol-1-yl group and in which the actyl group attached to the piperazine moiety is replaced by a p-[(+-)1-sec-butyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]phenyl group. A potent P-glycoprotein and CYP3A4 inhibitor, it is used as an antifungal drug for the treatment of various fungal infections, including aspergillosis, blastomycosis, candidiasis, chromoblastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, and sporotrichosis. FYPO_relaxed.owl CHEBI:82873 biolink:NamedThing 1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 4-chlorobenzyl group. FYPO_relaxed.owl CHEBI:82892 biolink:NamedThing 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole A member of the class of imidazoles that is 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethanol in which the hydroxyl hydrogen is replaced by a 2,4-dichlorobenzyl group. FYPO_relaxed.owl CHEBI:82979 biolink:NamedThing 1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine A dioxolane that is 1,3-dioxolane which is substituted at positions 2, 2, and 4 by 2,4-dichlorophenyl, 1H-1,2,4-triazol-1-ylmethyl, and [4-(4-isopropylpiperazin-1-yl)phenoxy]methyl groups, respectively. FYPO_relaxed.owl CHEBI:11814 biolink:NamedThing 3-hydroxy-3-methylglutaryl-CoA An alpha,omega dicarboxyacyl-CoA that results from the formal condensation of the thiol group of coenzyme A with one of the carboxy groups of 3-hydroxy-3-methylglutaric acid. FYPO_relaxed.owl CHEBI:20060 biolink:NamedThing 3-hydroxy fatty acyl-CoA A hydroxy fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any 3-hydroxy fatty acid. FYPO_relaxed.owl CHEBI:37555 biolink:NamedThing omega-carboxyacyl-CoA An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with one of the carboxy groups of any alpha,omega-dicarboxylic acid. FYPO_relaxed.owl CHEBI:24333 biolink:NamedThing glutaryl-CoAs Any omega-carboxyacyl-CoA in which the acyl group specified is glutaryl or its substituted derivative. FYPO_relaxed.owl CHEBI:12164 biolink:NamedThing 5-phosphoribosyl diphosphate A ribose diphosphate carrying an additional phosphate group at position 5. FYPO_relaxed.owl CHEBI:21080 biolink:NamedThing ribose diphosphate FYPO_relaxed.owl CHEBI:35158 biolink:NamedThing ribose bisphosphate FYPO_relaxed.owl CHEBI:12886 biolink:NamedThing (R)-4'-phosphopantothenate(1-) FYPO_relaxed.owl CHEBI:37481 biolink:NamedThing amidoalkyl phosphate FYPO_relaxed.owl CHEBI:15905 biolink:NamedThing (R)-4'-phosphopantothenic acid An amidoalkyl phosphate that is the 4-phosphate derivative of (R)-pantothenic acid. FYPO_relaxed.owl CHEBI:20891 biolink:NamedThing (R)-4'-phosphopantothenate(2-) FYPO_relaxed.owl CHEBI:12936 biolink:NamedThing D-galactose FYPO_relaxed.owl CHEBI:17608 biolink:NamedThing D-aldohexose Any D-aldose having a chain of six carbon atoms in the molecule. FYPO_relaxed.owl CHEBI:17634 biolink:NamedThing D-glucose A glucose with D-configuration. FYPO_relaxed.owl CHEBI:28260 biolink:NamedThing galactose An aldohexose that is the C-4 epimer of glucose. FYPO_relaxed.owl CHEBI:37621 biolink:NamedThing galactopyranose The pyranose form of galactose. FYPO_relaxed.owl CHEBI:130181 biolink:NamedThing calmodulin antagonist An antagonist that interferes with the action of the calcium-binding messenger protein calmodulin. FYPO_relaxed.owl CHEBI:48706 biolink:NamedThing antagonist Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. FYPO_relaxed.owl CHEBI:38215 biolink:NamedThing calcium channel blocker One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools. FYPO_relaxed.owl CHEBI:48561 biolink:NamedThing dopaminergic antagonist A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists. FYPO_relaxed.owl CHEBI:49020 biolink:NamedThing hormone antagonist A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. FYPO_relaxed.owl CHEBI:50792 biolink:NamedThing estrogen receptor antagonist An antagonist at the estrogen receptor. FYPO_relaxed.owl CHEBI:60798 biolink:NamedThing excitatory amino acid antagonist Any substance which inhibits the action of receptors for excitatory amino acids. FYPO_relaxed.owl CHEBI:65207 biolink:NamedThing vascular endothelial growth factor receptor antagonist An antagonist at the vascular endothelial growth factor receptor. FYPO_relaxed.owl CHEBI:65259 biolink:NamedThing GABA antagonist A compound that inhibits the action of gamma-aminobutyric acid. FYPO_relaxed.owl CHEBI:70774 biolink:NamedThing capsaicin receptor antagonist Any substance which blocks the painful sensation of heat caused by capsaicin acting on the TRPV1 ion channel. FYPO_relaxed.owl CHEBI:71232 biolink:NamedThing adenosine receptor antagonist An antagonist at any adenosine receptor. FYPO_relaxed.owl CHEBI:78681 biolink:NamedThing tropomyosin-related kinase B receptor antagonist An antagonist that binds to and deactivates the tropomyosin-related kinase B (TrkB) receptor, the main signaling receptor of the neurotrophin brain-derived neurotrophic factor (BDNF). FYPO_relaxed.owl CHEBI:82891 biolink:NamedThing glucocorticoid receptor antagonist An antagonist that binds to and deactivates glucocorticoid receptors. FYPO_relaxed.owl CHEBI:131401 biolink:NamedThing hexopyranosyl hexopyranoside A disaccharide formed by a (1<->1)-glycosidic bond between two hexopyranose units. FYPO_relaxed.owl CHEBI:24407 biolink:NamedThing glycosyl glycoside Any disaccharide in which the two monosaccharide components are connected by a glycosidic linkage between their anomeric centres. FYPO_relaxed.owl CHEBI:17992 biolink:NamedThing sucrose A glycosyl glycoside formed by glucose and fructose units joined by an acetal oxygen bridge from hemiacetal of glucose to the hemiketal of the fructose. FYPO_relaxed.owl CHEBI:131530 biolink:NamedThing pyridoxal(1+) A pyridinium ion obtained by protonation of the ring nitrogen of pyridoxal. FYPO_relaxed.owl CHEBI:27306 biolink:NamedThing vitamin B6 Any member of the group of pyridines that exhibit biological activity against vitamin B6 deficiency. Vitamin B6 deficiency is associated with microcytic anemia, electroencephalographic abnormalities, dermatitis with cheilosis (scaling on the lips and cracks at the corners of the mouth) and glossitis (swollen tongue), depression and confusion, and weakened immune function. Vitamin B6 consists of the vitamers pyridoxine, pyridoxal, and pyridoxamine and their respective 5'-phosphate esters (and includes their corresponding ionized and salt forms). FYPO_relaxed.owl CHEBI:131533 biolink:NamedThing pyridoxamine(2+) A pyridinium ion obtained by protonation of both nitrogens of pyridoxamine. FYPO_relaxed.owl CHEBI:16410 biolink:NamedThing pyridoxamine A monohydroxypyridine that is pyridine substituted by a hydroxy group at position 3, an aminomethyl group at position 4, a hydroxymethyl group at position 5 and a methyl group at position 2. The 4-aminomethyl form of vitamin B6, it is used (in the form of the hydrochloride salt) for treatment of diabetic nephropathy. FYPO_relaxed.owl CHEBI:16709 biolink:NamedThing pyridoxine A hydroxymethylpyridine with hydroxymethyl groups at positions 4 and 5, a hydroxy group at position 3 and a methyl group at position 2. The 4-methanol form of vitamin B6, it is converted intoto pyridoxal phosphate which is a coenzyme for synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. FYPO_relaxed.owl CHEBI:17310 biolink:NamedThing pyridoxal A pyridinecarbaldehyde that is pyridine-4-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 5 respectively. The 4-carboxyaldehyde form of vitamin B6, it is converted into pyridoxal phosphate, a coenzyme for the synthesis of amino acids, neurotransmitters, sphingolipids and aminolevulinic acid. FYPO_relaxed.owl CHEBI:36970 biolink:NamedThing vitamin B6 phosphate FYPO_relaxed.owl CHEBI:57761 biolink:NamedThing pyridoxaminium(1+) An ammonium ion that is the conjugate acid of pyridoxamine arising from selective protonation of the primary amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:50334 biolink:NamedThing pyridinium ion FYPO_relaxed.owl CHEBI:72290 biolink:NamedThing pyrithiamine A pyridinium ion that is 3-(2-hydroxyethyl)-2-methylpyridine substituted at position 1 by a (4-amino-2-methylpyrimidin-5-yl)methyl group. FYPO_relaxed.owl CHEBI:131604 biolink:NamedThing Mycoplasma genitalium metabolite Any bacterial metabolite produced during a metabolic reaction in Mycoplasma genitalium. FYPO_relaxed.owl CHEBI:76969 biolink:NamedThing bacterial metabolite Any prokaryotic metabolite produced during a metabolic reaction in bacteria. FYPO_relaxed.owl CHEBI:76971 biolink:NamedThing Escherichia coli metabolite Any bacterial metabolite produced during a metabolic reaction in Escherichia coli. FYPO_relaxed.owl CHEBI:76976 biolink:NamedThing bacterial xenobiotic metabolite Any bacterial metabolite produced by metabolism of a xenobiotic compound in bacteria. FYPO_relaxed.owl CHEBI:131605 biolink:NamedThing dicarboxylic acid monoester(1-) A carboxylic acid anion resulting from the deprotonation of the carboxy group of a dicarboxylic acid monoester. FYPO_relaxed.owl CHEBI:29067 biolink:NamedThing carboxylic acid anion The conjugate base formed when the carboxy group of a carboxylic acid is deprotonated. FYPO_relaxed.owl CHEBI:33721 biolink:NamedThing carbohydrate acid anion FYPO_relaxed.owl CHEBI:35693 biolink:NamedThing dicarboxylic acid anion FYPO_relaxed.owl CHEBI:35753 biolink:NamedThing tricarboxylic acid anion Any anion of a tricarboxylic acid formed by deprotonation of at least one carboxy group. FYPO_relaxed.owl CHEBI:35754 biolink:NamedThing tetracarboxylic acid anion Any anion of a tetracarboxylic acid formed by deprotonation of one or more carboxy groups. FYPO_relaxed.owl CHEBI:35757 biolink:NamedThing monocarboxylic acid anion A carboxylic acid anion formed when the carboxy group of a monocarboxylic acid is deprotonated. FYPO_relaxed.owl CHEBI:35903 biolink:NamedThing oxo carboxylic acid anion Any carboxylic acid anion containing at least one oxo group. FYPO_relaxed.owl CHEBI:37022 biolink:NamedThing amino-acid anion FYPO_relaxed.owl CHEBI:38716 biolink:NamedThing carboxylic acid dianion Any dianion containing at least one carboxy group. FYPO_relaxed.owl CHEBI:38717 biolink:NamedThing carboxylic acid trianion A trianion containing at least one carboxy group. FYPO_relaxed.owl CHEBI:59876 biolink:NamedThing N-acyl-D-alpha-amino acid anion The conjugate base of an N-acyl-D-alpha-amino acid arising from deprotonation of the C-1 carboxy group. FYPO_relaxed.owl CHEBI:63551 biolink:NamedThing carbohydrate acid derivative anion A carboxylic acid anion resulting from the deprotonation of the carboxy group of a carbohydrate acid derivative. FYPO_relaxed.owl CHEBI:66998 biolink:NamedThing histidinate derivative A carboxylic acid anion which is a conjugate base of a histidine derivative having either D- or L-configuration. FYPO_relaxed.owl CHEBI:91007 biolink:NamedThing aromatic carboxylate A carboxylic acic anion obtained by deprotonation of the carboxy group of any aromatic carboxylic acid. Major species at pH 7.3. FYPO_relaxed.owl CHEBI:131609 biolink:NamedThing pneumocandin B0 An echinocandin initially isolated as a very minor bioactive fermentation product of Glarea lozoyensis (originally known as Zalerion arboricola). Subsequent random mutagenesis work and optimisation of the fermentation medium permitted the industrial production of pneumocandin B0, which is used as the starting point for the synthesis of the antifungal drug caspofungin. FYPO_relaxed.owl CHEBI:24613 biolink:NamedThing homodetic cyclic peptide A homodetic cyclic peptide is a cyclic peptide in which the ring consists solely of amino-acid residues in peptide linkages. FYPO_relaxed.owl CHEBI:4031 biolink:NamedThing cyclosporin A A cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle. FYPO_relaxed.owl CHEBI:474180 biolink:NamedThing caspofungin A semisynthetic cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. FYPO_relaxed.owl CHEBI:61414 biolink:NamedThing ferrichromes Any member of a group of iron(III) chelates that are homodetic cyclic peptides made up of a tripeptide of glycine (or other small, neutral amino acid) and a tripeptide of an N(4)-acyl-N(4)-hydroxy-L-ornithine. FYPO_relaxed.owl CHEBI:84057 biolink:NamedThing trapoxin A A homodetic cyclic tetrapeptide constructed from L-phenylalanyl (x2), D-pipecolinyl and L-2-amino-8-oxo-9,10-epoxydecanoyl residues. FYPO_relaxed.owl CHEBI:90132 biolink:NamedThing deferrichrome A homodetic cyclic peptide composed from two units of three glycyl and three N(5)-acetyl-N(5)-hydroxy-L-ornithyl residues. FYPO_relaxed.owl CHEBI:57248 biolink:NamedThing echinocandin Any one of a family of large lipopeptides that are inhibitors of the enzyme 1,3-beta-glucan synthase, thus damaging fungal cell walls. Echinocandins are fungicidal against most Candida spp and fungistatic against Aspergillus spp. FYPO_relaxed.owl CHEBI:315019 biolink:NamedThing cilofungin A cyclic hexapeptide echinocandin antibiotic isolated from Aspergillus spp. By inhibiting the conversion of lanosterol to ergosterol, it invades a fungus' ability to synthesize cell walls. A modified form of echinocandin B, it is an antimycotic agent against Candida albicans. FYPO_relaxed.owl CHEBI:600520 biolink:NamedThing micafungin A cyclic hexapeptide echinocandin antibiotic which exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall. It is used as the sodium salt for the treatment of invasive candidiasis, and of aspergillosis in patients who are intolerant of other therapy. FYPO_relaxed.owl CHEBI:131738 biolink:NamedThing 2-tetradecanoyl-sn-glycero-3-phosphocholine A 2-acyl-sn-glycero-3-phosphocholine in which the acyl group is specified as tertadecanoyl (myristoyl). FYPO_relaxed.owl CHEBI:57875 biolink:NamedThing 2-acyl-sn-glycero-3-phosphocholine The ammonium betaine of a 2-acyl-sn-glycero-3-phosphocholine arising from deprotonation of the phosphate OH; major species at pH 7.3. FYPO_relaxed.owl CHEBI:131869 biolink:NamedThing hydroxy monounsaturated fatty acid Any monounsaturated fatty acid carrying one or more hydroxy substituents. FYPO_relaxed.owl CHEBI:24654 biolink:NamedThing hydroxy fatty acid Any fatty acid carrying one or more hydroxy substituents. FYPO_relaxed.owl CHEBI:140345 biolink:NamedThing hydroxy polyunsaturated fatty acid Any polyunsaturated fatty acid carrying one or more hydroxy substituents. FYPO_relaxed.owl CHEBI:52651 biolink:NamedThing leptomycin A complex, very long chain, polyunsaturated fatty acid whose core structure comprises 8-oxononadeca-2,10,12,16,18-pentaenoic acid having methyl substituents at positions 3, 5, 7, 9, 11 and 15 and a 3,6-dihydropyran-6-one-2-yl group at position 19. FYPO_relaxed.owl CHEBI:25413 biolink:NamedThing monounsaturated fatty acid Any fatty acid with one double or triple bond in the fatty acid chain and singly bonded carbon atoms in the rest of the chain. MUFAs have positive effects on the cardiovascular system, and in diabetes treatment. FYPO_relaxed.owl CHEBI:24580 biolink:NamedThing hexenoic acid A C6, medium-chain fatty acid carrying a double bond at any position along the main chain. FYPO_relaxed.owl CHEBI:25634 biolink:NamedThing octadecenoic acid Any member of the group of C18 monounsaturated fatty acids with the double bond located at any position in the chain. FYPO_relaxed.owl CHEBI:131870 biolink:NamedThing hydroxy monounsaturated fatty acid anion Any monounsaturated fatty acid anion carrying one or more hydroxy substituents. FYPO_relaxed.owl CHEBI:59835 biolink:NamedThing hydroxy fatty acid anion The conjugate base of any hydroxy fatty acid, formed by deprotonation of the carboxylic acid moiety. FYPO_relaxed.owl CHEBI:131871 biolink:NamedThing hydroxy polyunsaturated fatty acid anion Any polyunsaturated fatty acid anion carrying one or more hydroxy substituents. FYPO_relaxed.owl CHEBI:91295 biolink:NamedThing ricinoleate A hydroxy fatty acid anion that is the conjugate base of ricinoleic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:82680 biolink:NamedThing monounsaturated fatty acid anion Any unsaturated fatty acid anion with one double or triple bond in the fatty acid chain. FYPO_relaxed.owl CHEBI:78049 biolink:NamedThing octadecenoate A fatty acid anion containing 18 carbons and one double bond. Formed by deprotonation of the carboxylic acid group. Major species at pH 7.3. FYPO_relaxed.owl CHEBI:76567 biolink:NamedThing polyunsaturated fatty acid anion Any unsaturated fatty acid anion containing more than one C-C unsaturated bond. Major species at pH 7.3. FYPO_relaxed.owl CHEBI:131927 biolink:NamedThing dicarboxylic acids and O-substituted derivatives A class of carbonyl compound encompassing dicarboxylic acids and any derivatives obtained by substitution of either one or both of the carboxy hydrogens. FYPO_relaxed.owl CHEBI:36586 biolink:NamedThing carbonyl compound Any compound containing the carbonyl group, C=O. The term is commonly used in the restricted sense of aldehydes and ketones, although it actually includes carboxylic acids and derivatives. FYPO_relaxed.owl CHEBI:17087 biolink:NamedThing ketone A compound in which a carbonyl group is bonded to two carbon atoms: R2C=O (neither R may be H). FYPO_relaxed.owl CHEBI:17478 biolink:NamedThing aldehyde A compound RC(=O)H, in which a carbonyl group is bonded to one hydrogen atom and to one R group. FYPO_relaxed.owl CHEBI:33308 biolink:NamedThing carboxylic ester An ester of a carboxylic acid, R(1)C(=O)OR(2), where R(1) = H or organyl and R(2) = organyl. FYPO_relaxed.owl CHEBI:33575 biolink:NamedThing carboxylic acid A carbon oxoacid acid carrying at least one -C(=O)OH group and having the structure RC(=O)OH, where R is any any monovalent functional group. Carboxylic acids are the most common type of organic acid. FYPO_relaxed.owl CHEBI:51277 biolink:NamedThing thioester A compound of general formula RC(=O)SR'. Compare with thionoester, RC(=S)OR'. FYPO_relaxed.owl CHEBI:131982 biolink:NamedThing 1-icosenoyl-sn-glycero-3-phosphocholine A lysophosphatidylcholine 20:1 in which the acyl group is located at position 1. FYPO_relaxed.owl CHEBI:58168 biolink:NamedThing 1-O-acyl-sn-glycero-3-phosphocholine The ammonium betaine of a 1-O-acyl-sn-glycero-3-phosphocholine arising from deprotonation of the phosphate OH; major species at pH 7.3. FYPO_relaxed.owl CHEBI:73858 biolink:NamedThing 1-stearoyl-sn-glycero-3-phosphocholine A lysophosphatidylcholine 18:0 in which the acyl substituent is located at position 1 and is specified as stearoyl. FYPO_relaxed.owl CHEBI:132124 biolink:NamedThing 1,4-benzoquinones Any member of the class of benzoquinones that is 1,4-benzoquinone or its C-substituted derivatives. FYPO_relaxed.owl CHEBI:22729 biolink:NamedThing benzoquinones Any quinone resulting from the formal oxidation of catechol, hydroquinone, or their C-substituted derivatives. FYPO_relaxed.owl CHEBI:71648 biolink:NamedThing hydroxybenzoquinone Benzoquinones with at least one hydroxy substituent. FYPO_relaxed.owl CHEBI:25830 biolink:NamedThing p-quinones A quinone in which the two oxo groups of the quinone are located para to each other on the 6-membered quinonoid ring. FYPO_relaxed.owl CHEBI:132142 biolink:NamedThing 1,4-naphthoquinones A naphthoquinone in which the oxo groups of the quinone moiety are at positions 1 and 4 of the parent naphthalene ring. FYPO_relaxed.owl CHEBI:25357 biolink:NamedThing mitomycin A family of aziridine-containing natural products isolated from Streptomyces caespitosus or Streptomyces lavendulae. FYPO_relaxed.owl CHEBI:26255 biolink:NamedThing prenylquinone A quinone substituted by a polyprenyl-derived side-chain. Prenylquinones occur in all living cells. Due to their amphiphilic character, they are mainly located in biological membranes where they function as electron and proton carriers in the photosynthetic and respiratory electron transport chains. Some prenylquinones also perform more specialised roles sucy as antioxidants and enzyme cofactors. Prenylquinones are classified according to ring structure: the main classes are menaquinones, phylloquinones, ubiquinones and plastoquinones. FYPO_relaxed.owl CHEBI:28748 biolink:NamedThing doxorubicin FYPO_relaxed.owl CHEBI:47898 biolink:NamedThing 4'-epidoxorubicin An anthracycline that is the 4'-epi-isomer of doxorubicin. FYPO_relaxed.owl CHEBI:132130 biolink:NamedThing hydroxyquinone Any quinone in which one or more of the carbons making up the quinone moiety is substituted by a hydroxy group. FYPO_relaxed.owl CHEBI:33822 biolink:NamedThing organic hydroxy compound An organic compound having at least one hydroxy group attached to a carbon atom. FYPO_relaxed.owl CHEBI:24669 biolink:NamedThing hydroxy carboxylic acid Any carboxylic acid with at least one hydroxy group. FYPO_relaxed.owl CHEBI:26177 biolink:NamedThing polyene antibiotic A family of antibiotics containing a conjugated polyene moiety, usuallly isolated from some species of Streptomyces. FYPO_relaxed.owl CHEBI:26191 biolink:NamedThing polyol A compound that contains two or more hydroxy groups. FYPO_relaxed.owl CHEBI:30879 biolink:NamedThing alcohol A compound in which a hydroxy group, -OH, is attached to a saturated carbon atom. FYPO_relaxed.owl CHEBI:33823 biolink:NamedThing enol Alkenols; the term refers specifically to vinylic alcohols, which have the structure HOCR'=CR2. Enols are tautomeric with aldehydes (R' = H) or ketones (R' =/= H). FYPO_relaxed.owl CHEBI:33853 biolink:NamedThing phenols Organic aromatic compounds having one or more hydroxy groups attached to a benzene or other arene ring. FYPO_relaxed.owl CHEBI:35350 biolink:NamedThing hydroxy steroid FYPO_relaxed.owl CHEBI:73080 biolink:NamedThing hemiaminal Any organic amino compound that has an amino group and a hydroxy group attached to the same carbon atom. Hemiaminals are intermediates in the formation of imines by addition of an amine to an aldehyde or ketone; those derived from primary amines are particularly unstable. FYPO_relaxed.owl CHEBI:74818 biolink:NamedThing heteroaryl hydroxy compound Any organic aromatic compound having one or more hydroxy groups attached to a heteroarene ring. FYPO_relaxed.owl CHEBI:78802 biolink:NamedThing diarylheptanoid A family of plant metabolites with a common 1,7-diphenylheptane structural skeleton, carrying various substituents. They are mainly distributed in the roots, rhizomes and bark of Alpinia, Zingiber, Curcuma and Alnus species. FYPO_relaxed.owl CHEBI:36141 biolink:NamedThing quinone Compounds having a fully conjugated cyclic dione structure, such as that of benzoquinones, derived from aromatic compounds by conversion of an even number of -CH= groups into -C(=O)- groups with any necessary rearrangement of double bonds (polycyclic and heterocyclic analogues are included). FYPO_relaxed.owl CHEBI:25481 biolink:NamedThing naphthoquinone A polycyclic aromatic ketone metabolite of naphthalene. FYPO_relaxed.owl CHEBI:51285 biolink:NamedThing acenoquinone Quinones containing an acene fused ring system. FYPO_relaxed.owl CHEBI:132155 biolink:NamedThing hydroxynaphthoquinone Any naphthoquinone in which the naphthaoquinone moiety is substituted by at least one hydroxy group. FYPO_relaxed.owl CHEBI:132157 biolink:NamedThing hydroxy-1,4-naphthoquinone Any member of the class of 1,4-naphthoquinones in which the naphthoquinone moiety is substituted by at least one hydroxy group. FYPO_relaxed.owl CHEBI:28384 biolink:NamedThing vitamin K Any member of a group of fat-soluble 2-methyl-1,4-napthoquinones that exhibit biological activity against vitamin K deficiency. Vitamin K is required for the synthesis of prothrombin and certain other blood coagulation factors. FYPO_relaxed.owl CHEBI:132362 biolink:NamedThing citrate(4-) A citrate anion obtained by deprotonation of the three carboxy groups as well as the hydroxy group of citric acid. FYPO_relaxed.owl CHEBI:133748 biolink:NamedThing citrate anion A tricarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of citric acid. FYPO_relaxed.owl CHEBI:16947 biolink:NamedThing citrate(3-) A tricarboxylic acid trianion, obtained by deprotonation of the three carboxy groups of citric acid. FYPO_relaxed.owl CHEBI:35804 biolink:NamedThing citrate(1-) A tricarboxylic acid monoanion that is the conjugate base of citric acid, obtained by deprotonation of one of the three carboxy groups. FYPO_relaxed.owl CHEBI:35808 biolink:NamedThing citrate(2-) A tricarboxylic acid dianion obtained by deprotonation of two of the three carboxy groups of citric acid. FYPO_relaxed.owl CHEBI:132529 biolink:NamedThing N(4)-(oligosaccharide-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl)-L-asparagine residue An L-alpha-amino acid residue derived from any N(4)-(oligosaccharide-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl)-L-asparagine. FYPO_relaxed.owl CHEBI:83228 biolink:NamedThing L-alpha-amino acid residue An alpha-amino-acid residue derived from an L-alpha-amino acid. FYPO_relaxed.owl CHEBI:59108 biolink:NamedThing N(4)-glycosylated L-asparagine residue An L-asparagine residue having a glycosyl moiety attached to the side-chain amide nitrogen. FYPO_relaxed.owl CHEBI:132717 biolink:NamedThing bleaching agent A reagent that lightens or whitens a substrate through chemical reaction. Bleaching reactions usually involve oxidative or reductive processes that degrade colour systems. Bleaching can occur by destroying one or more of the double bonds in the conjugated chain, by cleaving the conjugated chain, or by oxidation of one of the other moieties in the conjugated chain. Their reactivity results in many bleaches having strong bactericidal, disinfecting, and sterilising properties. FYPO_relaxed.owl CHEBI:33893 biolink:NamedThing reagent A substance used in a chemical reaction to detect, measure, examine, or produce other substances. FYPO_relaxed.owl CHEBI:50684 biolink:NamedThing cross-linking reagent A reagent with two reactive groups, usually at opposite ends of the molecule, that are capable of reacting with and thereby forming bridges between macromolecules, principally side chains of amino acids in proteins, allowing the locations of naturally reactive areas within the proteins to be identified. FYPO_relaxed.owl CHEBI:59740 biolink:NamedThing nucleophilic reagent A reagent that forms a bond to its reaction partner (the electrophile) by donating both bonding electrons. FYPO_relaxed.owl CHEBI:67126 biolink:NamedThing colorimetric reagent A reagent used in the determination of the concentration of a coloured chemical element or chemical compound in solution. FYPO_relaxed.owl CHEBI:132943 biolink:NamedThing aspartate FYPO_relaxed.owl CHEBI:33558 biolink:NamedThing alpha-amino-acid anion An amino-acid anion obtained by deprotonation of any alpha-amino acid. FYPO_relaxed.owl CHEBI:14321 biolink:NamedThing glutamate(1-) An alpha-amino-acid anion that is the conjugate base of glutamic acid, having anionic carboxy groups and a cationic amino group FYPO_relaxed.owl CHEBI:32439 biolink:NamedThing alaninate An alpha-amino-acid anion that is the conjugate base of alanine, arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32456 biolink:NamedThing cysteinate(1-) A sulfur-containing amino-acid anion that is the conjugate base of cysteine, obtained by deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32457 biolink:NamedThing cysteinate(2-) FYPO_relaxed.owl CHEBI:32504 biolink:NamedThing phenylalaninate An aromatic amino-acid anion that is the conjugate base of phenylalanine, arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32508 biolink:NamedThing glycinate An alpha-amino-acid anion that is the conjugate base of glycine, arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32529 biolink:NamedThing histidinate(1-) FYPO_relaxed.owl CHEBI:32530 biolink:NamedThing histidinate(2-) FYPO_relaxed.owl CHEBI:32563 biolink:NamedThing lysinate An alpha-amino-acid anion that is the conjugate base of lysine, arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32612 biolink:NamedThing isoleucinate FYPO_relaxed.owl CHEBI:32627 biolink:NamedThing leucinate An alpha-amino-acid anion that is the conjugate base of leucine, arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32644 biolink:NamedThing methioninate A sulfur-containing amino-acid anion that is the conjugate base of methionine, arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32660 biolink:NamedThing asparaginate An alpha-amino-acid anion that is the conjugate base of asparagine, arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32678 biolink:NamedThing glutaminate An alpha-amino-acid anion that is the conjugate base of glutamine, arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32695 biolink:NamedThing argininate FYPO_relaxed.owl CHEBI:32727 biolink:NamedThing tryptophanate An alpha-amino-acid anion that is the conjugate base of tryptophan, arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32784 biolink:NamedThing tyrosinate(1-) An alpha-amino-acid anion that is the conjugate base of tyrosine, arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32785 biolink:NamedThing tyrosinate(2-) FYPO_relaxed.owl CHEBI:32832 biolink:NamedThing threoninate FYPO_relaxed.owl CHEBI:32845 biolink:NamedThing serinate An alpha-amino-acid anion that is the conjugate base of serine. FYPO_relaxed.owl CHEBI:32859 biolink:NamedThing valinate FYPO_relaxed.owl CHEBI:32871 biolink:NamedThing prolinate An alpha-amino-acid anion that is the conjugate base of proline, arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32964 biolink:NamedThing ornithinate FYPO_relaxed.owl CHEBI:59814 biolink:NamedThing L-alpha-amino acid anion Conjugate base of an L-alpha-amino acid arising from deprotonation of the C-1 carboxy group. FYPO_relaxed.owl CHEBI:60895 biolink:NamedThing D-alpha-amino acid anion Any alpha-amino acid anion in which the parent amino acid has D-configuration. FYPO_relaxed.owl CHEBI:62980 biolink:NamedThing homoserinate An alpha-amino-acid anion resulting from the removal of a proton from the carboxy group of homoserine. FYPO_relaxed.owl CHEBI:66922 biolink:NamedThing citrullinate An alpha-amino acid anion that is the conjugate base of citrulline, obtained by deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:66952 biolink:NamedThing homocysteinate An alpha-amino acid anion that is the conjugate base of homocysteine, obtained by deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:132951 biolink:NamedThing maleate A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of maleic acid. FYPO_relaxed.owl CHEBI:132953 biolink:NamedThing suberate A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of suberic acid. FYPO_relaxed.owl CHEBI:24329 biolink:NamedThing glutarate A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of glutaric acid. FYPO_relaxed.owl CHEBI:26806 biolink:NamedThing succinate A dicarboxylic acid anion obtained by deprotonation of at least one of the carboxy groups of succinic acid. FYPO_relaxed.owl CHEBI:28965 biolink:NamedThing dicarboxylic acid dianion A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid. FYPO_relaxed.owl CHEBI:35695 biolink:NamedThing dicarboxylic acid monoanion Any dicarboxylic acid anion that is a monoanion obtained by the deprotonation of only one of the carboxy groups of the dicarboxylic acid. FYPO_relaxed.owl CHEBI:132944 biolink:NamedThing octadec-9-enoate An octadecenoate in which the double bond is at C-9. FYPO_relaxed.owl CHEBI:132992 biolink:NamedThing radiosensitizing agent A drug that makes increases the sensitivity of tumour cells to radiation therapy. FYPO_relaxed.owl CHEBI:23888 biolink:NamedThing drug Any substance which when absorbed into a living organism may modify one or more of its functions. The term is generally accepted for a substance taken for a therapeutic purpose, but is also commonly used for abused substances. FYPO_relaxed.owl CHEBI:149552 biolink:NamedThing emetic Any agent that induces nausea and vomiting. FYPO_relaxed.owl CHEBI:35441 biolink:NamedThing antiinfective agent A substance used in the prophylaxis or therapy of infectious diseases. FYPO_relaxed.owl CHEBI:35470 biolink:NamedThing central nervous system drug A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system. FYPO_relaxed.owl CHEBI:35480 biolink:NamedThing analgesic An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. FYPO_relaxed.owl CHEBI:35498 biolink:NamedThing diuretic An agent that promotes the excretion of urine through its effects on kidney function. FYPO_relaxed.owl CHEBI:35523 biolink:NamedThing bronchodilator agent An agent that causes an increase in the expansion of a bronchus or bronchial tubes. FYPO_relaxed.owl CHEBI:35526 biolink:NamedThing hypoglycemic agent A drug which lowers the blood glucose level. FYPO_relaxed.owl CHEBI:35554 biolink:NamedThing cardiovascular drug A drug that affects the rate or intensity of cardiac contraction, blood vessel diameter or blood volume. FYPO_relaxed.owl CHEBI:35610 biolink:NamedThing antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms. FYPO_relaxed.owl CHEBI:35679 biolink:NamedThing antilipemic drug A substance used to treat hyperlipidemia (an excess of lipids in the blood). FYPO_relaxed.owl CHEBI:35842 biolink:NamedThing antirheumatic drug A drug used to treat rheumatoid arthritis. FYPO_relaxed.owl CHEBI:35942 biolink:NamedThing neurotransmitter agent A substance used for its pharmacological action on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. FYPO_relaxed.owl CHEBI:47868 biolink:NamedThing photosensitizing agent A chemical compound that can be excited by light of a specific wavelength and subsequently transfer energy to a chosen reactant. This is commonly molecular oxygen within a cancer tissue, which is converted to (highly rective) singlet state oxygen. This rapidly reacts with any nearby biomolecules, ultimately killing the cancer cells. FYPO_relaxed.owl CHEBI:48422 biolink:NamedThing angiogenesis inhibitor An agent and endogenous substances that antagonize or inhibit the development of new blood vessels. FYPO_relaxed.owl CHEBI:49167 biolink:NamedThing anti-asthmatic drug A drug used to treat asthma. FYPO_relaxed.owl CHEBI:49201 biolink:NamedThing anti-ulcer drug One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. FYPO_relaxed.owl CHEBI:50177 biolink:NamedThing dermatologic drug A drug used to treat or prevent skin disorders or for the routine care of skin. FYPO_relaxed.owl CHEBI:50248 biolink:NamedThing hematologic agent Drug that acts on blood and blood-forming organs and those that affect the hemostatic system. FYPO_relaxed.owl CHEBI:50266 biolink:NamedThing prodrug A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug. FYPO_relaxed.owl CHEBI:50267 biolink:NamedThing protective agent Synthetic or natural substance which is given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent. FYPO_relaxed.owl CHEBI:50646 biolink:NamedThing bone density conservation agent An agent that inhibits bone resorption and/or favor bone mineralization and bone regeneration. Used to heal bone fractures and to treat bone diseases such as osteopenia and osteoporosis. FYPO_relaxed.owl CHEBI:50689 biolink:NamedThing reproductive control drug A substance used either in the prevention or facilitation of pregnancy. FYPO_relaxed.owl CHEBI:50733 biolink:NamedThing nutraceutical A product in capsule, tablet or liquid form that provide essential nutrients, such as a vitamin, an essential mineral, a protein, an herb, or similar nutritional substance. FYPO_relaxed.owl CHEBI:50739 biolink:NamedThing estrogen receptor modulator A substance that possess antiestrogenic actions but can also produce estrogenic effects as well. It acts as complete or partial agonist or as antagonist. It can be either steroidal or nonsteroidal in structure. FYPO_relaxed.owl CHEBI:50846 biolink:NamedThing immunomodulator Biologically active substance whose activity affects or plays a role in the functioning of the immune system. FYPO_relaxed.owl CHEBI:50919 biolink:NamedThing antiemetic A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors. FYPO_relaxed.owl CHEBI:50926 biolink:NamedThing angiogenesis modulating agent An agent that modulates the physiologic angiogenesis process. This is accomplished by endogenous angiogenic proteins and a variety of other chemicals and pharmaceutical agents. FYPO_relaxed.owl CHEBI:52726 biolink:NamedThing proteasome inhibitor A drug that blocks the action of proteasomes, cellular complexes that break down proteins. FYPO_relaxed.owl CHEBI:74783 biolink:NamedThing astringent A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions. FYPO_relaxed.owl CHEBI:88188 biolink:NamedThing drug allergen Any drug which causes the onset of an allergic reaction. FYPO_relaxed.owl CHEBI:90710 biolink:NamedThing receptor modulator A drug that acts as an antagonist, agonist, reverse agonist, or in some other fashion when interacting with cellular receptors. FYPO_relaxed.owl CHEBI:133092 biolink:NamedThing gamma-Glu-Abu A dipeptide obtained by formal condensation of the gamma-carboxy group of glutamic acid with the amino group of 2-aminobutyric acid. FYPO_relaxed.owl CHEBI:46761 biolink:NamedThing dipeptide Any molecule that contains two amino-acid residues connected by peptide linkages. FYPO_relaxed.owl CHEBI:64530 biolink:NamedThing brevianamide F A pyrrolopyrazine that is hexahydropyrrolo[1,2-a]pyrazine-1,4-dione bearing an indol-3-ylmethyl substituent at position 3 (the 3S,8aS-diastereomer, obtained by formal cyclocondensation of L-tryptophan and L-proline). FYPO_relaxed.owl CHEBI:72760 biolink:NamedThing tryprostatin B A cyclic dipeptide that is brevianamide F (cyclo-L-Trp-L-Pro) substituted at position 2 on the indole ring by a prenyl group. FYPO_relaxed.owl CHEBI:133093 biolink:NamedThing gamma-Glu-Abu(1-) A peptide anion that is the conjugate base of gamma-Glu-Abu, obtained by removal of protons from the two carboxy groups as well as protonation of the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:60334 biolink:NamedThing peptide anion An anion formed by deprotonation of at least one peptide carboxy group. FYPO_relaxed.owl CHEBI:145544 biolink:NamedThing S-nitrosoglutathione(1-) A peptide anion obtained by deprotonation of both carboxy groups and protonation of the glutamyl amino group of S-nitrosoglutathione; major species at pH 7.3. FYPO_relaxed.owl CHEBI:43056 biolink:NamedThing S-nitrosoglutathione(2-) A peptide anion obtained by deprotonation of both carboxy groups of S-nitrosoglutathione. FYPO_relaxed.owl CHEBI:57925 biolink:NamedThing glutathionate(1-) A peptide anion obtained by deprotonation of both carboxy groups and protonation of the glutamyl amino group of glutathione; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58297 biolink:NamedThing glutathione disulfide(2-) A doubly-charged peptide anion arising from deprotonation of the four carboxy groups and protonation of the two amino groups of glutathione disulfide; major species at pH 7.3. FYPO_relaxed.owl CHEBI:133131 biolink:NamedThing spiro-epoxide An oxaspiro compound in which a carbon atom of an epoxide ring is the only common member of two rings. FYPO_relaxed.owl CHEBI:32955 biolink:NamedThing epoxide Any cyclic ether in which the oxygen atom forms part of a 3-membered ring. FYPO_relaxed.owl CHEBI:171741 biolink:NamedThing cerulenin An epoxydodecadienamide isolated from several species, including Acremonium, Acrocylindrum and Helicoceras. It inhibits the biosynthesis of several lipids by interfering with enzyme function. FYPO_relaxed.owl CHEBI:29515 biolink:NamedThing ansamitocin P3 A polyketide antibiotic that is isolated from Actinosynnema pretiosum and also exhibits antitumour activity. FYPO_relaxed.owl CHEBI:29623 biolink:NamedThing manumycin A A polyketide with formula C31H38N2O7 initially isolated from Streptomyces parvulus as a result of a random screening program for farnesyl transferase (FTase) inhibitors. It is a natural product that exhibits anticancer and antibiotic properties. FYPO_relaxed.owl CHEBI:556075 biolink:NamedThing radicicol An antifungal macrolactone antibiotic, obtained from Diheterospora chlamydosporia and Chaetomium chiversii that inhibits protein tyrosine kinase and heat shock protein 90 (Hsp90). FYPO_relaxed.owl CHEBI:72590 biolink:NamedThing rhizoxin An macrolide antibiotic isolated from the pathogenic plant fungus Rhizopus microsporus. It also exhibits antitumour and antimitotic activity. FYPO_relaxed.owl CHEBI:9688 biolink:NamedThing trichodermin A tetracyclic spiroepoxide which acts as an antifungal and protein synthesis inhibitor. FYPO_relaxed.owl CHEBI:37948 biolink:NamedThing oxaspiro compound A spiro compound in which at least one of the cyclic components is an oxygen heterocyle. FYPO_relaxed.owl CHEBI:72600 biolink:NamedThing spiroketal A cyclic ketal in which the ketal carbon is the only common atom of two rings. FYPO_relaxed.owl CHEBI:133135 biolink:NamedThing chromenochromene Any organic heteroolycyclic compound whose skeleton two ortho-fused chromene rings, and their derivatives. FYPO_relaxed.owl CHEBI:38166 biolink:NamedThing organic heteropolycyclic compound FYPO_relaxed.owl CHEBI:22727 biolink:NamedThing benzopyran FYPO_relaxed.owl CHEBI:26979 biolink:NamedThing organic heterotricyclic compound An organic tricyclic compound in which at least one of the rings of the tricyclic skeleton contains one or more heteroatoms. FYPO_relaxed.owl CHEBI:27171 biolink:NamedThing organic heterobicyclic compound FYPO_relaxed.owl CHEBI:35259 biolink:NamedThing benzofurans FYPO_relaxed.owl CHEBI:36468 biolink:NamedThing polycyclic ether FYPO_relaxed.owl CHEBI:38163 biolink:NamedThing organic heterotetracyclic compound FYPO_relaxed.owl CHEBI:38164 biolink:NamedThing organic heteropentacyclic compound FYPO_relaxed.owl CHEBI:38165 biolink:NamedThing organic heterooctacyclic compound FYPO_relaxed.owl CHEBI:39203 biolink:NamedThing dibenzopyran Any organic heteropolycyclic compound based on a skeleton consisting of a pyran ring fused with two benzene rings. FYPO_relaxed.owl CHEBI:51915 biolink:NamedThing indolocarbazole Compounds based upon an indolo[2,3-a]carbazole skeleton. FYPO_relaxed.owl CHEBI:133241 biolink:NamedThing omega-carboxyacyl-CoA(5-) An acyl-CoA oxoanion obtained by deprotonation of the phosphate, diphosphate and carboxy groups of any omega-carboxyacyl-CoA; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57384 biolink:NamedThing malonyl-CoA(5-) Pentaanion of malonyl-CoA arising from deprotonation of phosphate, diphosphate and carboxylic acid functions. FYPO_relaxed.owl CHEBI:58342 biolink:NamedThing acyl-CoA(4-) An acyl-CoA oxoanion arising from deprotonation of the phosphate and diphosphate OH groups of any acyl-CoA; major species at pH 7.3. FYPO_relaxed.owl CHEBI:133251 biolink:NamedThing 3-hydroxydicarboxylate(2-) A dicarboxylic acid dianion that results from the removal of a proton from both of the carboxylic acid groups of any 3-hydroxydicarboxylic acid. FYPO_relaxed.owl CHEBI:133291 biolink:NamedThing saturated dicarboxylic acid dianion(2-) A carboxylic acid dianion obtained by deprotonation of both carboxy groups of any dicarboxylic acid that contains no carbon-carbon double bonds. FYPO_relaxed.owl CHEBI:133294 biolink:NamedThing oxo dicarboxylic acid dianion A dicarboxylic acid dianion obtained by deprotonation of both carboxy groups of any oxo dicarboxylic acid. FYPO_relaxed.owl CHEBI:189846 biolink:NamedThing dicarboxylic fatty acid dianion Any fatty acid that contains 2 carboxylic groups. Major microspecies at pH 7.3 FYPO_relaxed.owl CHEBI:29987 biolink:NamedThing glutamate(2-) A dicarboxylic acid dianion that is the conjugate base of glutamate(1-). FYPO_relaxed.owl CHEBI:30921 biolink:NamedThing glutarate(2-) A dicarboxylic acid dianion obtained by deprotonation of both the carboxy groups of glutaric acid. FYPO_relaxed.owl CHEBI:36147 biolink:NamedThing oxo dicarboxylate FYPO_relaxed.owl CHEBI:50681 biolink:NamedThing methotrexate(2-) FYPO_relaxed.owl CHEBI:61336 biolink:NamedThing C4-dicarboxylate A dicarboxylate that contains four carbon atoms. FYPO_relaxed.owl CHEBI:35902 biolink:NamedThing oxo monocarboxylic acid anion FYPO_relaxed.owl CHEBI:59836 biolink:NamedThing oxo fatty acid anion A fatty acid anion carrying one or more oxo substituents FYPO_relaxed.owl CHEBI:133538 biolink:NamedThing L-lysine zwitterion An L-alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of L-lysine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:59869 biolink:NamedThing L-alpha-amino acid zwitterion Zwitterionic form of an L-alpha-amino acid having an anionic carboxy group and a protonated amino group. FYPO_relaxed.owl CHEBI:29991 biolink:NamedThing L-aspartate(1-) An aspartate(1-) that is the conjugate base of L-aspartic acid. FYPO_relaxed.owl CHEBI:57762 biolink:NamedThing L-valine zwitterion An L-alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of L-valine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57912 biolink:NamedThing L-tryptophan zwitterion An L-alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of L-tryptophan; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58045 biolink:NamedThing L-isoleucine zwitterion An L-alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of L-isoleucine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:82705 biolink:NamedThing hercynylselenocysteine zwitterion An L-alpha-amino acid zwitterion formed from hercynylselenocysteine by transfer of a proton from the carboxy to the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:82706 biolink:NamedThing hercynylcysteine sulfoxide zwitterion An L-alpha-amino acid zwitterion formed from hercynylcysteine sulfoxide by transfer of a proton from the carboxy to the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:27092 biolink:NamedThing tricarboxylic acid trianion FYPO_relaxed.owl CHEBI:36299 biolink:NamedThing tricarboxylic acid monoanion FYPO_relaxed.owl CHEBI:36300 biolink:NamedThing tricarboxylic acid dianion FYPO_relaxed.owl CHEBI:133750 biolink:NamedThing Cutin-1 A phosphonium ylide that is 2-(triphenylphosphoranylidene)acetamide in which the nitrogen has been converted to the corresponding carbamoyl derivative. By targeting the beta-subunit of fatty acid synthase, it inhibits nuclear envelope expansion and nuclear elongation during the closed mitosis of fission yeast. FYPO_relaxed.owl CHEBI:51154 biolink:NamedThing phosphonium ylide Compounds having the structure R3P(+)-C(-)R2 <-> R3P=CR2, where the phosphorus atom is bonded to four separate atoms. FYPO_relaxed.owl CHEBI:74266 biolink:NamedThing N-acylurea A member of the class of ureas that has the general formula R-CO-NH-CO-NH2 or R-CO-NH-CO-NH-CO-R', formally derived by the acylation of one or both of the nitrogens of a urea moiety. FYPO_relaxed.owl CHEBI:134043 biolink:NamedThing phenylureas Any member of the class of ureas in which at least one of the nitrogens of the urea moiety is substituted by a phenyl or substituted phenyl group. FYPO_relaxed.owl CHEBI:22712 biolink:NamedThing benzenes Any benzenoid aromatic compound consisting of the benzene skeleton and its substituted derivatives. FYPO_relaxed.owl CHEBI:16716 biolink:NamedThing benzene A six-carbon aromatic annulene in which each carbon atom donates one of its two 2p electrons into a delocalised pi system. A toxic, flammable liquid byproduct of coal distillation, it is used as an industrial solvent. Benzene is a carcinogen that also damages bone marrow and the central nervous system. FYPO_relaxed.owl CHEBI:22562 biolink:NamedThing anilines Any aromatic amine that is benzene carrying at least one amino substituent and its substituted derivatives. FYPO_relaxed.owl CHEBI:22723 biolink:NamedThing benzoic acids Any aromatic carboxylic acid that consists of benzene in which at least a single hydrogen has been substituted by a carboxy group. FYPO_relaxed.owl CHEBI:23132 biolink:NamedThing chlorobenzenes Any organochlorine compound containing a benzene ring which is substituted by one or more chlorines. FYPO_relaxed.owl CHEBI:26775 biolink:NamedThing stilbene FYPO_relaxed.owl CHEBI:27024 biolink:NamedThing toluenes Any member of the class of benzenes that is a substituted benzene in which the substituents include one (and only one) methyl group. FYPO_relaxed.owl CHEBI:35496 biolink:NamedThing fluorobenzenes Any fluoroarene that is a benzene or a substituted benzene carrying at least one fluoro group. FYPO_relaxed.owl CHEBI:38976 biolink:NamedThing alkylbenzene A monocyclic arene that is benzene substituted with one or more alkyl groups. FYPO_relaxed.owl CHEBI:41033 biolink:NamedThing benzamidine A carboxamidine that is benzene carrying an amidino group. FYPO_relaxed.owl CHEBI:51683 biolink:NamedThing methoxybenzenes Any aromatic ether that consists of a benzene skeleton substituted with one or more methoxy groups. FYPO_relaxed.owl CHEBI:47857 biolink:NamedThing ureas FYPO_relaxed.owl CHEBI:44423 biolink:NamedThing hydroxyurea A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease. FYPO_relaxed.owl CHEBI:134179 biolink:NamedThing volatile organic compound Any organic compound having an initial boiling point less than or equal to 250 degreeC (482 degreeF) measured at a standard atmospheric pressure of 101.3 kPa. FYPO_relaxed.owl CHEBI:72695 biolink:NamedThing organic molecule Any molecule that consists of at least one carbon atom as part of the electrically neutral entity. FYPO_relaxed.owl CHEBI:33832 biolink:NamedThing organic cyclic compound Any organic molecule that consists of atoms connected in the form of a ring. FYPO_relaxed.owl CHEBI:35716 biolink:NamedThing C-nitro compound A nitro compound having the nitro group (-NO2) attached to a carbon atom. FYPO_relaxed.owl CHEBI:36587 biolink:NamedThing organic oxo compound Organic compounds containing an oxygen atom, =O, doubly bonded to carbon or another element. FYPO_relaxed.owl CHEBI:51151 biolink:NamedThing dipolar compound An organic molecule that is electrically neutral carrying a positive and a negative charge in one of its major canonical descriptions. In most dipolar compounds the charges are delocalized; however the term is also applied to species where this is not the case. FYPO_relaxed.owl CHEBI:73474 biolink:NamedThing acetylenic compound Any organic molecule containing a C#C bond. FYPO_relaxed.owl CHEBI:134249 biolink:NamedThing alkanesulfonate oxoanion An alkanesulfonate in which the carbon at position 1 is attached to R, which can represent hydrogens, a carbon chain, or other groups. FYPO_relaxed.owl CHEBI:33554 biolink:NamedThing organosulfonate oxoanion An organic anion obtained by deprotonation of the sufonate group(s) of any organosulfonic acid. FYPO_relaxed.owl CHEBI:22713 biolink:NamedThing arenesulfonate oxoanion FYPO_relaxed.owl CHEBI:63945 biolink:NamedThing ferrozine(2-) An organosulfonate oxoanion obtained by deprotonation of the sulfo groups of 4,4'-[3-(pyridin-2-yl)-1,2,4-triazine-5,6-diyl]dibenzenesulfonic acid. FYPO_relaxed.owl CHEBI:134344 biolink:NamedThing ergothioneine(1+) An alpha-amino-acid cation obtained by protonation of the imidazole ring of ergothioneine. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). FYPO_relaxed.owl CHEBI:33719 biolink:NamedThing alpha-amino-acid cation FYPO_relaxed.owl CHEBI:32440 biolink:NamedThing alaninium An alpha-amino-acid cation that is the conjugate acid of alanine. FYPO_relaxed.owl CHEBI:32458 biolink:NamedThing cysteinium FYPO_relaxed.owl CHEBI:32505 biolink:NamedThing phenylalaninium An alpha-amino-acid cation that is the conjugate acid of phenylalanine, arising from protonation of the amino group. FYPO_relaxed.owl CHEBI:32507 biolink:NamedThing glycinium An alpha-amino-acid cation that is the conjugate acid of glycine, arising from protonation of the amino. FYPO_relaxed.owl CHEBI:32531 biolink:NamedThing histidinium(1+) FYPO_relaxed.owl CHEBI:32532 biolink:NamedThing histidinium(2+) FYPO_relaxed.owl CHEBI:32564 biolink:NamedThing lysinium(1+) An alpha-amino-acid cation that is the conjugate acid of lysine, having two cationic amino groups and an anionic carboxy group. FYPO_relaxed.owl CHEBI:32565 biolink:NamedThing lysinium(2+) An alpha-amino-acid cation obtained by protonation of both amino groups of lysine. FYPO_relaxed.owl CHEBI:32613 biolink:NamedThing isoleucinium FYPO_relaxed.owl CHEBI:32628 biolink:NamedThing leucinium An alpha-amino-acid cation that is the conjugate acid of leucine, arising from protonation of the amino group. FYPO_relaxed.owl CHEBI:32646 biolink:NamedThing methioninium A sulfur-containing amino-acid cation that is the conjugate acid of methionine, arising from protonation of the amino group. FYPO_relaxed.owl CHEBI:32661 biolink:NamedThing asparaginium FYPO_relaxed.owl CHEBI:32679 biolink:NamedThing glutaminium An alpha-amino-acid cation that is the conjugate acid of glutamine, arising from protonation of the amino group. FYPO_relaxed.owl CHEBI:32696 biolink:NamedThing argininium(1+) FYPO_relaxed.owl CHEBI:32697 biolink:NamedThing argininium(2+) FYPO_relaxed.owl CHEBI:32728 biolink:NamedThing tryptophanium An alpha-amino-acid cation that is the conjugate acid of tryptophan, arising from protonation of the alpha-amino group. FYPO_relaxed.owl CHEBI:32786 biolink:NamedThing tyrosinium An alpha-amino-acid cation that is the conjugate acid of tyrosine, arising from protonation of the amino group. FYPO_relaxed.owl CHEBI:32833 biolink:NamedThing threoninium FYPO_relaxed.owl CHEBI:32846 biolink:NamedThing serinium An alpha-amino-acid cation that is the conjugate acid of serine. FYPO_relaxed.owl CHEBI:32860 biolink:NamedThing valinium FYPO_relaxed.owl CHEBI:32872 biolink:NamedThing prolinium An alpha-amino-acid cation that is the conjugate acid of proline, arising from protonation of the amino group. FYPO_relaxed.owl CHEBI:46912 biolink:NamedThing ornithinium(1+) FYPO_relaxed.owl CHEBI:46913 biolink:NamedThing ornithinium(2+) FYPO_relaxed.owl CHEBI:78902 biolink:NamedThing L-canavanine(1+) An alpha-amino-acid cation that is the conjugate acid of L-canavanine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:134361 biolink:NamedThing allylic alcohol An alcohol where the hydroxy group is attached to a saturated carbon atom adjacent to a double bond (R groups may be H, organyl, etc.). FYPO_relaxed.owl CHEBI:139588 biolink:NamedThing alpha-hydroxy ketone An alpha-oxyketone that has a hydroxy group as the alpha-oxy moiety. FYPO_relaxed.owl CHEBI:15734 biolink:NamedThing primary alcohol A primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it. FYPO_relaxed.owl CHEBI:22478 biolink:NamedThing amino alcohol An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group. FYPO_relaxed.owl CHEBI:2571 biolink:NamedThing aliphatic alcohol An alcohol derived from an aliphatic compound. FYPO_relaxed.owl CHEBI:26244 biolink:NamedThing prenols Any alcohol possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of one or more isoprene units (biogenetic precursors of the isoprenoids). FYPO_relaxed.owl CHEBI:26878 biolink:NamedThing tertiary alcohol A tertiary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has three other carbon atoms attached to it. FYPO_relaxed.owl CHEBI:33854 biolink:NamedThing aromatic alcohol Any alcohol in which the alcoholic hydroxy group is attached to a carbon which is itself bonded to an aromatic ring. FYPO_relaxed.owl CHEBI:35681 biolink:NamedThing secondary alcohol A secondary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has two other carbon atoms attached to it. FYPO_relaxed.owl CHEBI:5653 biolink:NamedThing hemiacetal A compound having the general formula RR'C(OH)OR'' (R'' =/= H). FYPO_relaxed.owl CHEBI:78840 biolink:NamedThing olefinic compound Any organic molecular entity that contains at least one C=C bond. FYPO_relaxed.owl CHEBI:134362 biolink:NamedThing homoallylic alcohol An aliphatic alcohol where the hydroxy carbon is beta to a double bond. FYPO_relaxed.owl CHEBI:23252 biolink:NamedThing cinnamic acids Any alpha,beta-unsaturated monocarboxylic acid based on the cinnamic acid skeleton and its substituted derivatives. FYPO_relaxed.owl CHEBI:26776 biolink:NamedThing stilbenoid Any olefinic compound characterised by a 1,2-diphenylethylene backbone. FYPO_relaxed.owl CHEBI:33641 biolink:NamedThing olefin Acyclic and cyclic hydrocarbons having one or more carbon-carbon double bonds, apart from the formal ones in aromatic compounds. The class olefins subsumes alkenes and cycloalkenes and the corresponding polyenes. FYPO_relaxed.owl CHEBI:41922 biolink:NamedThing diethylstilbestrol An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups. FYPO_relaxed.owl CHEBI:47989 biolink:NamedThing enamine An amine RNR'R'' where R has a double bond adjacent to the amine nitrogen. FYPO_relaxed.owl CHEBI:51689 biolink:NamedThing enone An alpha,beta-unsaturated ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) in which the C=O function is conjugated to a C=C double bond at the alpha,beta position. FYPO_relaxed.owl CHEBI:51702 biolink:NamedThing enoate ester An alpha,beta-unsaturated carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) in which the ester C=O function is conjugated to a C=C double bond at the alpha,beta position. FYPO_relaxed.owl CHEBI:51751 biolink:NamedThing enamide An alpha,beta-unsaturated carboxylic acid amide of general formula R(1)R(2)C=CR(3)-C(=O)NR(4)R(5) in which the amide C=O function is conjugated to a C=C double bond at the alpha,beta position. FYPO_relaxed.owl CHEBI:53339 biolink:NamedThing olefinic fatty acid Any fatty acid containing at least one C=C double bond. FYPO_relaxed.owl CHEBI:59831 biolink:NamedThing enyne An acetylenic and an olefinic compound containing a carbon chain that contains a carbon-carbon double bond and a carbon-carbon triple bond. FYPO_relaxed.owl CHEBI:79385 biolink:NamedThing YW3548 A terpene lactone that is obtained from Codinea simplex and acts as an inhibitor of glycerophosphoinositol biosynthesis. FYPO_relaxed.owl CHEBI:83265 biolink:NamedThing papuamide B A cyclodepsipeptide that is isolated from Papua New Guinea collections of the marine sponges Theonella mirabilis and Theonella swinhoei. It exhbits anti-HIV-1 activity and cytotoxicity against some human cancer cell lines. FYPO_relaxed.owl CHEBI:84340 biolink:NamedThing hydrazinocurcumin A pyrazole obtained by cyclocodensation of the two carbonyl groups of curcumin with hydrazine. FYPO_relaxed.owl CHEBI:50584 biolink:NamedThing alkyl alcohol An aliphatic alcohol in which the aliphatic alkane chain is substituted by a hydroxy group at unspecified position. FYPO_relaxed.owl CHEBI:134394 biolink:NamedThing primary allylic alcohol An allylic alcohol in which the carbon atom that links the double bond to the hydroxy group is also attached to two hydrogens. FYPO_relaxed.owl CHEBI:134396 biolink:NamedThing secondary allylic alcohol An allylic alcohol in which the carbon atom that links the double bond to the hydroxy group is also attached to one other carbon and one hydrogen. FYPO_relaxed.owl CHEBI:139590 biolink:NamedThing primary alpha-hydroxy ketone An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a -CH2 (methylene) group. FYPO_relaxed.owl CHEBI:16000 biolink:NamedThing ethanolamine A member of the class of ethanolamines that is ethane with an amino substituent at C-1 and a hydroxy substituent at C-2, making it both a primary amine and a primary alcohol. FYPO_relaxed.owl CHEBI:17790 biolink:NamedThing methanol The primary alcohol that is the simplest aliphatic alcohol, comprising a methyl and an alcohol group. FYPO_relaxed.owl CHEBI:23982 biolink:NamedThing ethanols Any primary alcohol based on an ethanol skeleton. FYPO_relaxed.owl CHEBI:26300 biolink:NamedThing propenol FYPO_relaxed.owl CHEBI:26874 biolink:NamedThing terpenol FYPO_relaxed.owl CHEBI:41218 biolink:NamedThing mercaptoethanol FYPO_relaxed.owl CHEBI:2468 biolink:NamedThing secondary alpha-hydroxy ketone An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing one hydrogen and one organyl group. Secondary alpha-hydroxy ketones are also known as acyloins, and are formally derived from reductive coupling of two carboxylic acid groups. FYPO_relaxed.owl CHEBI:27641 biolink:NamedThing cycloheximide A dicarboximide that is 4-(2-hydroxyethyl)piperidine-2,6-dione in which one of the hydrogens attached to the carbon bearing the hydroxy group is replaced by a 3,5-dimethyl-2-oxocyclohexyl group. It is an antibiotic produced by the bacterium Streptomyces griseus. FYPO_relaxed.owl CHEBI:36836 biolink:NamedThing 3beta-hydroxy steroid A 3-hydroxy steroid in which the 3-hydroxy substituent is in the beta-position. FYPO_relaxed.owl CHEBI:529996 biolink:NamedThing cytochalasin D An organic heterotricyclic compound that is a mycotoxin produced by Helminthosporium and other moulds which is cell permeable and a potent inhibitor of actin polymerisation and DNA synthesis. FYPO_relaxed.owl CHEBI:62064 biolink:NamedThing butane-2,3-diol A butanediol in which hydroxylation is at C-2 and C-3. FYPO_relaxed.owl CHEBI:63618 biolink:NamedThing pravastatin A carboxylic ester resulting from the formal condensation of (S)-2-methylbutyric acid with the hydroxy group adjacent to the ring junction of (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid. Derived from microbial transformation of mevastatin, pravastatin is a reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA). The sodium salt is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin. FYPO_relaxed.owl CHEBI:85616 biolink:NamedThing viridicatumtoxin A tetracycline-like polyketide antibiotic that is produced by several species of Penicillium and Aspergillus. FYPO_relaxed.owl CHEBI:85639 biolink:NamedThing (9Z)-12-hydroxyoctadec-9-enoic acid A hydroxy fatty acid that is (9Z)-octadec-9-enoic (oleic) acid carrying a hydroxy substituent at position 12. FYPO_relaxed.owl CHEBI:9168 biolink:NamedThing sirolimus A macrolide lactam isolated from Streptomyces hygroscopicus consisting of a 29-membered ring containing 4 trans double bonds, three of which are conjugated. It is an antibiotic, immunosupressive and antineoplastic agent. FYPO_relaxed.owl CHEBI:134547 biolink:NamedThing TOP-53 A furonaphthodioxole that is 4'-demethyldeoxypodophyllotoxin which is substituted at position 4 of the C-ring by a 2-{[2-(dimethylamino)ethyl](methyl)amino}ethyl group. While structurally related to etoposide, TOP-53 is significantly more toxic to non-small cell lung cancer cells, more active at generating chromosomal breaks, and displays improved cellular uptake and pharmacokinetics in animal lung tissues. FYPO_relaxed.owl CHEBI:139520 biolink:NamedThing phenolic donor Any phenol that acts as an electron donor. FYPO_relaxed.owl CHEBI:142517 biolink:NamedThing tschimganine A benzoate ester resulting from the formal condensation of the carboxy group of vanillic acid with the hydroxy group of (-)-borneol. A metabolite isolated from Ferula dissecta. FYPO_relaxed.owl CHEBI:15882 biolink:NamedThing phenol An organic hydroxy compound that consists of benzene bearing a single hydroxy substituent. The parent of the class of phenols. FYPO_relaxed.owl CHEBI:172923 biolink:NamedThing fluorescein (acid form) A xanthene dye that is highly fluorescent and commonly used as a fluorescent tracer. FYPO_relaxed.owl CHEBI:22901 biolink:NamedThing bisphenol By usage, the methylenediphenols, HOC6H4CH2C6H4OH, commonly p,p-methylenediphenol, and their substitution products (generally derived from condensation of two equivalent amounts of a phenol with an aldehyde or ketone). The term also includes analogues in the the methylene (or substituted methylene) group has been replaced by a heteroatom. FYPO_relaxed.owl CHEBI:24031 biolink:NamedThing ferulic acids FYPO_relaxed.owl CHEBI:24676 biolink:NamedThing hydroxybenzoic acid Any benzoic acid carrying one or more phenolic hydroxy groups on the benzene ring. FYPO_relaxed.owl CHEBI:24727 biolink:NamedThing hydroxynaphthalene Any member of the class of naphthalenes that is naphthalene carrying one or more hydroxy groups. FYPO_relaxed.owl CHEBI:26195 biolink:NamedThing polyphenol Members of the class of phenols that contain 2 or more benzene rings each of which is substituted by at least one hydroxy group. FYPO_relaxed.owl CHEBI:2762 biolink:NamedThing antimycin A A nine-membered bis-lactone having methyl substituents at the 2- and 6-positions, an n-hexyl substituent at the 8-position, an acyloxy substituent at the 7-position and an aroylamido substituent at the 3-position. It is produced by Streptomyces bacteria and has found commercial use as a fish poison. FYPO_relaxed.owl CHEBI:33570 biolink:NamedThing benzenediols FYPO_relaxed.owl CHEBI:34247 biolink:NamedThing 2,6-di-tert-butyl-4-methylphenol A member of the class of phenols that is 4-methylphenol substituted by tert-butyl groups at positions 2 and 6. FYPO_relaxed.owl CHEBI:46209 biolink:NamedThing L-tyrosinal An amino aldehyde that is L-tyrosine in which the carboxy group has undergone formal redution to give the corrresponding aldehyde FYPO_relaxed.owl CHEBI:64110 biolink:NamedThing 4,4',4''-(4-propylpyrazole-1,3,5-triyl)trisphenol A pyrazole that is 1H-pyrazole bearing three 4-hydroxyphenyl substituents at positions 1, 3 and 5 as well as a propyl substituent at position 4. Potent, subtype-selective estrogen receptor agonist (EC50 ~ 200 pM); displays 410-fold selectivity for ERalpha over ERbeta. Prevents ovariectomy-induced weight gain and loss of bone mineral density, and induces gene expression in the hypothalamus following systemic administration in vivo. FYPO_relaxed.owl CHEBI:74422 biolink:NamedThing 4'-demethylepipodophyllotoxin An organic heterotetracyclic compound that is the 9- epimer of 4'-demethylpodophyllotoxin. FYPO_relaxed.owl CHEBI:76357 biolink:NamedThing 2-tert-butyl-4-hydroxyanisole An aromatic ether that is 4-methoxyphenol in which one of the hydrogens ortho- to the methoxy group is replaced by a tert-butyl group. FYPO_relaxed.owl CHEBI:76358 biolink:NamedThing 3-tert-butyl-4-hydroxyanisole An aromatic ether that is 4-methoxyphenol in which one of the hydrogens ortho- to the phenolic hydroxy group is replaced by a tert-butyl group. FYPO_relaxed.owl CHEBI:8273 biolink:NamedThing plumbagin A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 2 and 5 are substituted by methyl and hydroxy groups, respectively. FYPO_relaxed.owl CHEBI:87193 biolink:NamedThing 2',4',5',7'-tetrabromo-2,3,4,5-tetrachlorofluorescein A xanthene dye that is fluorescein bearing bromine substituents at positions 2', 4', 5' and 7' (on the xanthene ring) and chlorine substituents at position 2, 3, 4, and 5 (on the phenyl ring). The disodium salt is the biological stain 'phloxine B'. FYPO_relaxed.owl CHEBI:37581 biolink:NamedThing gamma-lactone A lactone having a five-membered lactone ring. FYPO_relaxed.owl CHEBI:50307 biolink:NamedThing furonaphthodioxole FYPO_relaxed.owl CHEBI:4911 biolink:NamedThing etoposide FYPO_relaxed.owl CHEBI:50305 biolink:NamedThing podophyllotoxin An organic heterotetracyclic compound that has a furonaphthodioxole skeleton bearing a 3,4,5-trimethoxyphenyl substituent. It is found in the roots and rhizomes of Podophyllum species and is used for the topical treatment of genital warts. FYPO_relaxed.owl CHEBI:50996 biolink:NamedThing tertiary amino compound A compound formally derived from ammonia by replacing three hydrogen atoms by organyl groups. FYPO_relaxed.owl CHEBI:2663 biolink:NamedThing amiodarone A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias. FYPO_relaxed.owl CHEBI:30740 biolink:NamedThing ethylene glycol bis(2-aminoethyl)tetraacetic acid A diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively. FYPO_relaxed.owl CHEBI:32876 biolink:NamedThing tertiary amine A compound formally derived from ammonia by replacing three hydrogen atoms by hydrocarbyl groups. FYPO_relaxed.owl CHEBI:41774 biolink:NamedThing tamoxifen FYPO_relaxed.owl CHEBI:46845 biolink:NamedThing N-alkylpiperazine FYPO_relaxed.owl CHEBI:46848 biolink:NamedThing N-arylpiperazine FYPO_relaxed.owl CHEBI:50154 biolink:NamedThing 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane A nitroso compound that is triazane in which the the nitrogen at position 1 is substituted by two 2-aminoethyl groups, that at position 2 is substituted by a hydroxy group, and that at position 3 is substituted by an oxo group. FYPO_relaxed.owl CHEBI:70723 biolink:NamedThing reversine A member of the class of purines that is 9H-purine in which the hydrogens at positions 2 and 6 are replaced by a [4-(morpholin-4-yl)phenyl]nitrilo group and a cyclohexylamino group, respectively. FYPO_relaxed.owl CHEBI:70726 biolink:NamedThing hesperadin An oxindole that is indolin-2-one which is substituted at position 5 by an (ethylsulfonyl)nitrilo group and at position 2 by a methylidene group, which is itself substituted by a phenyl group and a [4-(piperidin-1-ylmethyl)phenyl]amino group. An Aurora B kinase inhibitor, it is used to inhibit chromosome alignment and segregation. FYPO_relaxed.owl CHEBI:85572 biolink:NamedThing Ku-0063794 A member of the class of pyridopyrimidines that is an mTOR inhibitor and shows anti-tumour properties. FYPO_relaxed.owl CHEBI:13497 biolink:NamedThing UDP-alpha-D-glucosamine A UDP-amino sugar having alpha-D-glucosamine as the amino-sugar component. FYPO_relaxed.owl CHEBI:35262 biolink:NamedThing UDP-amino sugar FYPO_relaxed.owl CHEBI:16264 biolink:NamedThing UDP-N-acetyl-alpha-D-glucosamine A UDP-amino sugar having N-acetyl-alpha-D-glucosamine as the amino sugar component. FYPO_relaxed.owl CHEBI:13643 biolink:NamedThing glycol A diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent. FYPO_relaxed.owl CHEBI:23824 biolink:NamedThing diol A compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic. Aliphatic diols are also called glycols. FYPO_relaxed.owl CHEBI:17698 biolink:NamedThing chloramphenicol An organochlorine compound that is dichloro-substituted acetamide containing a nitrobenzene ring, an amide bond and two alcohol functions. FYPO_relaxed.owl CHEBI:22501 biolink:NamedThing aminodiol An amino alcohol having two hydroxy functional groups. FYPO_relaxed.owl CHEBI:22944 biolink:NamedThing butanediols A diol that is a butanediol or a derivative of a butanediol. FYPO_relaxed.owl CHEBI:136505 biolink:NamedThing homocysteine derivative A non-proteinogenic amino acid derivative resulting from reaction of homocysteine at the amino group, the carboxy group, or the side-chain amino group, or from the replacement of any hydrogen of homocysteine by a heteroatom. The definition normally excludes peptides containing homocysteine residues. FYPO_relaxed.owl CHEBI:83812 biolink:NamedThing non-proteinogenic amino acid derivative Any derivative of a non-proteinogenic amino acid resulting from reaction at an amino group or carboxy group, or from the replacement of any hydrogen by a heteroatom. FYPO_relaxed.owl CHEBI:15778 biolink:NamedThing N-acyl-D-amino acid Any N-acyl-amino acid in which the amino acid moiety has D configuration. FYPO_relaxed.owl CHEBI:22823 biolink:NamedThing beta-alanine derivative FYPO_relaxed.owl CHEBI:136622 biolink:NamedThing aci-nitro compound Organonitrogen compounds that have the general structure R(1)(R(2))C=N(O)OH (R(1),R(2) = H, organyl). They are tautomers of C-nitro compounds. FYPO_relaxed.owl CHEBI:35352 biolink:NamedThing organonitrogen compound Any heteroorganic entity containing at least one carbon-nitrogen bond. FYPO_relaxed.owl CHEBI:142677 biolink:NamedThing triazinoindole Any heterotricyclic compound whose skeleton consists of an indole fused to a triazine ring. FYPO_relaxed.owl CHEBI:21731 biolink:NamedThing N-glycosyl compound A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a nitrogen atom, thus creating a C-N bond. FYPO_relaxed.owl CHEBI:22315 biolink:NamedThing alkaloid Any of the naturally occurring, basic nitrogen compounds (mostly heterocyclic) occurring mostly in the plant kingdom, but also found in bacteria, fungi, and animals. By extension, certain neutral compounds biogenetically related to basic alkaloids are also classed as alkaloids. Amino acids, peptides, proteins, nucleotides, nucleic acids, amino sugars and antibiotics are not normally regarded as alkaloids. Compounds in which the nitrogen is exocyclic (dopamine, mescaline, serotonin, etc.) are usually classed as amines rather than alkaloids. FYPO_relaxed.owl CHEBI:23424 biolink:NamedThing cyanides Salts and C-organyl derivatives of hydrogen cyanide, HC#N. FYPO_relaxed.owl CHEBI:24337 biolink:NamedThing glutathione derivative Any organonitrogen compound derived from the Glu-Cys-Gly tripeptide glutathione. FYPO_relaxed.owl CHEBI:24436 biolink:NamedThing guanidines Any organonitrogen compound containing a carbamimidamido (guanidino) group. Guanidines have the general structure (R(1)R(2)N)(R(3)R(4)N)C=N-R(5) and are related structurally to amidines and ureas. FYPO_relaxed.owl CHEBI:26469 biolink:NamedThing quaternary nitrogen compound A nitrogen molecular entity that is electronically neutral but which contains a quaternary nitrogen. FYPO_relaxed.owl CHEBI:26739 biolink:NamedThing sphingolipid Sphingolipids are a complex family of compounds that share a common structural feature, a sphingoid base backbone. FYPO_relaxed.owl CHEBI:28616 biolink:NamedThing carbamic acid A one-carbon compound that is ammonia in which one of the hydrogens is replaced by a carboxy group. Although carbamic acid derivatives are common, carbamic acid itself has never been synthesised. FYPO_relaxed.owl CHEBI:35359 biolink:NamedThing carboxamidine Compounds having the structure RC(=NR)NR2. The term is used as a suffix in systematic nomenclature to denote the -C(=NH)NH2 group including its carbon atom. FYPO_relaxed.owl CHEBI:37598 biolink:NamedThing nitrogen mustard Compounds having two beta-haloalkyl groups bound to a nitrogen atom, as in (X-CH2-CH2)2NR. FYPO_relaxed.owl CHEBI:37622 biolink:NamedThing carboxamide An amide of a carboxylic acid, having the structure RC(=O)NR2. The term is used as a suffix in systematic name formation to denote the -C(=O)NH2 group including its carbon atom. FYPO_relaxed.owl CHEBI:38101 biolink:NamedThing organonitrogen heterocyclic compound Any organonitrogen compound containing a cyclic component with nitrogen and at least one other element as ring member atoms. FYPO_relaxed.owl CHEBI:38127 biolink:NamedThing thiocarbamic ester Any organonitrogen compound with formula RS-C(=X)NH2 where X = O (monothiocarbamic esters) or S (dithiocarbamic esters), or their N-substituted derivatives. FYPO_relaxed.owl CHEBI:38532 biolink:NamedThing hydrazone Compounds having the structure R2C=NNR2, formally derived from aldehydes or ketones by replacing =O by =NNH2 (or substituted analogues). FYPO_relaxed.owl CHEBI:48378 biolink:NamedThing carboximidic acid FYPO_relaxed.owl CHEBI:50047 biolink:NamedThing organic amino compound A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by organyl groups. FYPO_relaxed.owl CHEBI:50335 biolink:NamedThing organic nitrogen anion FYPO_relaxed.owl CHEBI:75769 biolink:NamedThing B vitamin Any member of the group of eight water-soluble vitamins originally thought to be a single compound (vitamin B) that play important roles in cell metabolism. The group comprises of vitamin B1, B2, B3, B5, B6, B7, B9, and B12 (Around 20 other compounds were once thought to be B vitamins but are no longer classified as such). FYPO_relaxed.owl CHEBI:83813 biolink:NamedThing proteinogenic amino acid Any of the 23 alpha-amino acids that are precursors to proteins, and are incorporated into proteins during translation. The group includes the 20 amino acids encoded by the nuclear genes of eukaryotes together with selenocysteine, pyrrolysine, and N-formylmethionine. Apart from glycine, which is non-chiral, all have L configuration. FYPO_relaxed.owl CHEBI:83821 biolink:NamedThing amino acid derivative Any derivative of an amino acid resulting from reaction at an amino group, carboxy group, side-chain functional group, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing amino acid residues. FYPO_relaxed.owl CHEBI:87127 biolink:NamedThing allylamine antifungal drug An organonitrogen compound that contains an amino group that is attached to a carbon which is itself attached to an olefinic carbon and which has been used as an antifungal drug. FYPO_relaxed.owl CHEBI:136859 biolink:NamedThing pro-agent A compound that, on administration, undergoes conversion by biochemical (enzymatic), chemical (possibly following an enzymatic step), or physical (e.g. photochemical) activation processes before becoming the active agent for which it is a pro-agent. FYPO_relaxed.owl CHEBI:33232 biolink:NamedThing application Intended use of the molecular entity or part thereof by humans. FYPO_relaxed.owl CHEBI:25944 biolink:NamedThing pesticide Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. FYPO_relaxed.owl CHEBI:27780 biolink:NamedThing detergent A surfactant (or a mixture containing one or more surfactants) having cleaning properties in dilute solutions. FYPO_relaxed.owl CHEBI:33286 biolink:NamedThing agrochemical An agrochemical is a substance that is used in agriculture or horticulture. FYPO_relaxed.owl CHEBI:33292 biolink:NamedThing fuel An energy-rich substance that can be transformed with release of usable energy. FYPO_relaxed.owl CHEBI:37958 biolink:NamedThing dye FYPO_relaxed.owl CHEBI:46787 biolink:NamedThing solvent A liquid that can dissolve other substances (solutes) without any change in their chemical composition. FYPO_relaxed.owl CHEBI:47867 biolink:NamedThing indicator Anything used in a scientific experiment to indicate the presence of a substance or quality, change in a body, etc. FYPO_relaxed.owl CHEBI:50406 biolink:NamedThing probe A role played by a molecular entity used to study the microscopic environment. FYPO_relaxed.owl CHEBI:50533 biolink:NamedThing protein denaturant FYPO_relaxed.owl CHEBI:52217 biolink:NamedThing pharmaceutical Any substance introduced into a living organism with therapeutic or diagnostic purpose. FYPO_relaxed.owl CHEBI:64047 biolink:NamedThing food additive Any substance which is added to food to preserve or enhance its flavour and/or appearance. FYPO_relaxed.owl CHEBI:64345 biolink:NamedThing MALDI matrix material A compound used to form the matrix for MALDI (matrix-assisted laser desorption/ionization) mass spectrometry. MALDI matrix materials are crystalline compounds with a fairly low molecular weight, so as to allow facile vaporization, have strong absorption at UV or IR wavelengths (to rapidly and efficiently absorb laser irradiation), generally contain polar groups (enabling them to be used in aqueous solutions) and are frequently acidic (so assisting ionisation of the compound being studied, which is contained within the matrix material). FYPO_relaxed.owl CHEBI:64857 biolink:NamedThing cosmetic The role played by a substance in enhancing the appearance or odour of the human body; a name given to the substance itself or to a component of it. FYPO_relaxed.owl CHEBI:65023 biolink:NamedThing anti-asthmatic agent Any compound that has anti-asthmatic effects. FYPO_relaxed.owl CHEBI:67079 biolink:NamedThing anti-inflammatory agent Any compound that has anti-inflammatory effects. FYPO_relaxed.owl CHEBI:76414 biolink:NamedThing propellant A compressed gas or liquid with a boiling point lower than room temperature which to used to propel and dispense liquids such as deodorants, insecticides, paints, etc. from aerosol cans. FYPO_relaxed.owl CHEBI:78433 biolink:NamedThing refrigerant A substance used in a thermodynamic heat pump cycle or refrigeration cycle that undergoes a phase change from a gas to a liquid and back. Refrigerants are used in air-conditioning systems and freezers or refrigerators and are assigned a "R" number (by ASHRAE - formerly the American Society of Heating, Refrigerating and Air Conditioning Engineers), which is determined systematically according to their molecular structure. FYPO_relaxed.owl CHEBI:79314 biolink:NamedThing flame retardant Any compound that is added to manufactured materials to inhibit, suppress, or delay the production of flames and so prevent the spread of fire. FYPO_relaxed.owl CHEBI:137419 biolink:NamedThing secondary ammonium ion An organic cation obtained by protonation of any secondary amino compound; major species at pH 7.3. FYPO_relaxed.owl CHEBI:25697 biolink:NamedThing organic cation Any organic ion with a net positive charge. FYPO_relaxed.owl CHEBI:137982 biolink:NamedThing tertiary ammonium ion An organic cation obtained by protonation of the amino group of any tertiary amino compound. FYPO_relaxed.owl CHEBI:34905 biolink:NamedThing paraquat An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions. FYPO_relaxed.owl CHEBI:35267 biolink:NamedThing quaternary ammonium ion A derivative of ammonium, NH4(+), in which all four of the hydrogens bonded to nitrogen have been replaced with univalent (usually organyl) groups. FYPO_relaxed.owl CHEBI:35286 biolink:NamedThing iminium ion Cations of structure R2C=N(+)R2. FYPO_relaxed.owl CHEBI:53238 biolink:NamedThing 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium An organic cation that is tetrazolium substituted with a dimethylthiazolyl group and two phenyl groups. The cation exists in two resonance forms. FYPO_relaxed.owl CHEBI:57834 biolink:NamedThing spermidine(3+) An ammonium ion that is the trication of spermidine, formed by protonation at all three nitrogens. FYPO_relaxed.owl CHEBI:59789 biolink:NamedThing S-adenosyl-L-methionine zwitterion A zwitterionic tautomer of S-adenosyl-L-methionine arising from shift of the proton from the carboxy group to the amino group. FYPO_relaxed.owl CHEBI:63048 biolink:NamedThing 1,3-thiazolium cation An organic cation resulting from protonation or quaternisation at the 3-position of any 1,3-thiazole. FYPO_relaxed.owl CHEBI:64087 biolink:NamedThing vanoxerine(2+) A organic cation obtained by protonation of the two tertiary amino functions of vanoxerine FYPO_relaxed.owl CHEBI:64290 biolink:NamedThing erythromycin cation An organic cation obtained by protonation of any erythromycin. FYPO_relaxed.owl CHEBI:64678 biolink:NamedThing anthracycline cation An organic cation obtained by protonation of any anthracycline. FYPO_relaxed.owl CHEBI:65296 biolink:NamedThing primary ammonium ion An ammonium ion derivative resulting from the protonation of the nitrogen atom of a primary amino compound. Major species at pH 7.3. FYPO_relaxed.owl CHEBI:70977 biolink:NamedThing alkane-alpha,omega-diammonium(2+) An organic cation obtained by protonation of the amino groups of any alkane-alpha,omega-diamine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:77615 biolink:NamedThing terbinafine(1+) An organic cation that is the conjugate acid of terbinafine, obtained by protonation of the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:83876 biolink:NamedThing cationic sphingoid An organic cation obtained by protonation of the amino function of any sphingoid FYPO_relaxed.owl CHEBI:84745 biolink:NamedThing amiloride(1+) An organic cation obtained by protonation of amiloride. FYPO_relaxed.owl CHEBI:85612 biolink:NamedThing triplatin(4+) A platinum coordination entity that is the cationic portion of triplatin tetranitrate. FYPO_relaxed.owl CHEBI:35274 biolink:NamedThing ammonium ion derivative A derivative of ammonium, NH4(+), in which one (or more) of the hydrogens bonded to the nitrogen have been replaced with univalent organyl groups. The substituting carbon of the organyl group must not itself be directly attached to a heteroatom (thereby excluding protonated amides, hemiaminals, etc). FYPO_relaxed.owl CHEBI:57491 biolink:NamedThing staurosporinium Conjugate acid of staurosporine. FYPO_relaxed.owl CHEBI:57668 biolink:NamedThing D-ornithinium(1+) The conjugate acid of D-ornithine having an anionic carboxy group and both amino groups protonated; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57699 biolink:NamedThing L-histidinol(1+) An ammonium ion that is the conjugate acid of L-histidinol arising from protonation of the primary amino function; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57971 biolink:NamedThing hygromycin B(3+) An ammonium ion that is the trication of hygromycin B arising from protonation of the three amino groups; major species at pH 7.3. FYPO_relaxed.owl CHEBI:59338 biolink:NamedThing methylammonium The conjugate acid of methylamine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:137626 biolink:NamedThing EC 1.1.1.146 (11beta-hydroxysteroid dehydrogenase) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of 11beta-hydroxysteroid dehydrogenase (EC 1.1.1.146). FYPO_relaxed.owl CHEBI:76835 biolink:NamedThing EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that uses NAD(+) or NADP(+) as acceptor (EC 1.1.1.*). FYPO_relaxed.owl CHEBI:35664 biolink:NamedThing EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 1.1.1.34 for the NADPH-dependent enzyme and EC 1.1.1.88 for an NADH-dependent enzyme. FYPO_relaxed.owl CHEBI:48550 biolink:NamedThing EC 1.1.1.21 (aldehyde reductase) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21). FYPO_relaxed.owl CHEBI:53746 biolink:NamedThing EC 1.1.1.205 (IMP dehydrogenase) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of IMP dehydrogenase (EC 1.1.1.205), so blocking de novo biosynthesis of purine nucleotides. FYPO_relaxed.owl CHEBI:77484 biolink:NamedThing EC 1.1.1.25 (shikimate dehydrogenase) inhibitor An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of shikimate dehydrogenase (EC 1.1.1.25). FYPO_relaxed.owl CHEBI:137980 biolink:NamedThing metalloid atom An atom of an element that exhibits properties that are between those of metals and nonmetals, or that has a mixture of them. The term generally includes boron, silicon, germanium, arsenic, antimony, and tellurium, while carbon, aluminium, selenium, polonium, and astatine are less commonly included. FYPO_relaxed.owl CHEBI:33250 biolink:NamedThing atom A chemical entity constituting the smallest component of an element having the chemical properties of the element. FYPO_relaxed.owl CHEBI:25585 biolink:NamedThing nonmetal atom FYPO_relaxed.owl CHEBI:33318 biolink:NamedThing main group element atom An atom belonging to one of the main groups (found in the s- and p- blocks) of the periodic table. FYPO_relaxed.owl CHEBI:33521 biolink:NamedThing metal atom An atom of an element that exhibits typical metallic properties, being typically shiny, with high electrical and thermal conductivity. FYPO_relaxed.owl CHEBI:33559 biolink:NamedThing s-block element atom FYPO_relaxed.owl CHEBI:138015 biolink:NamedThing endocrine disruptor Any compound that can disrupt the functions of the endocrine (hormone) system FYPO_relaxed.owl CHEBI:51061 biolink:NamedThing hormone receptor modulator A drug that modulates the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. FYPO_relaxed.owl CHEBI:138029 biolink:NamedThing 14alpha-methyl steroid Any steroid carrying a 14alpha-methyl substituent. FYPO_relaxed.owl CHEBI:35341 biolink:NamedThing steroid Any of naturally occurring compounds and synthetic analogues, based on the cyclopenta[a]phenanthrene carbon skeleton, partially or completely hydrogenated; there are usually methyl groups at C-10 and C-13, and often an alkyl group at C-17. By extension, one or more bond scissions, ring expansions and/or ring contractions of the skeleton may have occurred. Natural steroids are derived biogenetically from squalene which is a triterpene. FYPO_relaxed.owl CHEBI:35508 biolink:NamedThing steroid fundamental parent FYPO_relaxed.owl CHEBI:47880 biolink:NamedThing steroid ester FYPO_relaxed.owl CHEBI:50403 biolink:NamedThing ergostanoid FYPO_relaxed.owl CHEBI:138103 biolink:NamedThing inorganic acid A Bronsted acid derived from one or more inorganic compounds. Inorganic acids (also known as mineral acids) form hydrons and conjugate base ions when dissolved in water. FYPO_relaxed.owl CHEBI:39141 biolink:NamedThing Bronsted acid A molecular entity capable of donating a hydron to an acceptor (Bronsted base). FYPO_relaxed.owl CHEBI:48356 biolink:NamedThing protic solvent A polar solvent that is capable of acting as a hydron (proton) donor. FYPO_relaxed.owl CHEBI:138108 biolink:NamedThing 2-palmitoleoyl-sn-glycero-3-phospho-D-myo-inositol A 2-acyl-sn-glycero-3-phospho-D-myo-inositol that has palmitoleoyl as the acyl group. FYPO_relaxed.owl CHEBI:62746 biolink:NamedThing 2-acyl-sn-glycero-3-phospho-D-myo-inositol A 2-acylglycerophosphoinositol in which sn-glycerol, acylated at O(2), is linked through a phospho group at O(3) to O(1) of D-myo-inositol. FYPO_relaxed.owl CHEBI:138208 biolink:NamedThing carotenoid biosynthesis inhibitor Any pathway inhibitor that acts on the carotenoid biosynthesis pathway. FYPO_relaxed.owl CHEBI:76932 biolink:NamedThing pathway inhibitor An enzyme inhibitor that interferes with one or more steps in a metabolic pathway. FYPO_relaxed.owl CHEBI:140921 biolink:NamedThing Hedgehog signaling pathway inhibitor Any pathway inhibitor that inhibits the Hedgehog signalling pathway. FYPO_relaxed.owl CHEBI:38496 biolink:NamedThing electron-transport chain inhibitor FYPO_relaxed.owl CHEBI:48001 biolink:NamedThing protein synthesis inhibitor A compound, usually an anti-bacterial agent or a toxin, which inhibits the synthesis of a protein. FYPO_relaxed.owl CHEBI:50185 biolink:NamedThing fatty acid synthesis inhibitor Any pathway inhibitor that inhibits the synthesis of fatty acids. FYPO_relaxed.owl CHEBI:59517 biolink:NamedThing DNA synthesis inhibitor Any substance that inhibits the synthesis of DNA. FYPO_relaxed.owl CHEBI:79386 biolink:NamedThing glycerophosphoinositol synthesis inhibitor A pathway inhibitor that disrupts the synthesis of glycerophosphoinositol FYPO_relaxed.owl CHEBI:138238 biolink:NamedThing pyrimidine ribonucleoside 5'-monophosphate(2-) A nucleoside 5'-monophosphate(2-) obtained by deprotonation of the phospohate OH groups of any pyrimidine ribonucleoside 5'-monophosphate; major species at pH 7.3. FYPO_relaxed.owl CHEBI:138675 biolink:NamedThing gas molecular entity Any main group molecular entity that is gaseous at standard temperature and pressure (STP; 0degreeC and 100 kPa). FYPO_relaxed.owl CHEBI:33579 biolink:NamedThing main group molecular entity A molecular entity containing one or more atoms from any of groups 1, 2, 13, 14, 15, 16, 17, and 18 of the periodic table. FYPO_relaxed.owl CHEBI:33674 biolink:NamedThing s-block molecular entity An s-block molecular entity is a molecular entity containing one or more atoms of an s-block element. FYPO_relaxed.owl CHEBI:33675 biolink:NamedThing p-block molecular entity A main group molecular entity that contains one or more atoms of a p-block element. FYPO_relaxed.owl CHEBI:36562 biolink:NamedThing main-group coordination entity A coordination entity in which the central atom to which the ligands are attached comes from groups 1, 2, 13, 14, 15, 16, 17, or 18 of the periodic table. FYPO_relaxed.owl CHEBI:138880 biolink:NamedThing autophagy inducer Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell). FYPO_relaxed.owl CHEBI:52206 biolink:NamedThing biochemical role A biological role played by the molecular entity or part thereof within a biochemical context. FYPO_relaxed.owl CHEBI:173084 biolink:NamedThing ferroptosis inhibitor Any substance that inhibits the process of ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms. FYPO_relaxed.owl CHEBI:173085 biolink:NamedThing ferroptosis inducer Any substance that induces or promotes ferroptosis (a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides) in organisms. FYPO_relaxed.owl CHEBI:23357 biolink:NamedThing cofactor An organic molecule or ion (usually a metal ion) that is required by an enzyme for its activity. It may be attached either loosely (coenzyme) or tightly (prosthetic group). FYPO_relaxed.owl CHEBI:23924 biolink:NamedThing enzyme inhibitor A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. FYPO_relaxed.owl CHEBI:25212 biolink:NamedThing metabolite Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. FYPO_relaxed.owl CHEBI:33229 biolink:NamedThing vitamin (role) A biochemical role played by any micronutrient that is an organic compound. Vitamins are present in foods in small amounts and are essential to normal metabolism and biochemical functions, usually as coenzymes. The term "vitamines" (from vita + amines) was coined in 1912 by Casimir Funk, who believed that these compounds were amines. FYPO_relaxed.owl CHEBI:35221 biolink:NamedThing antimetabolite A substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization. FYPO_relaxed.owl CHEBI:35224 biolink:NamedThing effector A small molecule which increases (activator) or decreases (inhibitor) the activity of an (allosteric) enzyme by binding to the enzyme at the regulatory site (which is different from the substrate-binding catalytic site). FYPO_relaxed.owl CHEBI:68494 biolink:NamedThing apoptosis inhibitor Any substance that inhibits the process of apoptosis (programmed cell death) in multi-celled organisms. FYPO_relaxed.owl CHEBI:68495 biolink:NamedThing apoptosis inducer Any substance that induces the process of apoptosis (programmed cell death) in multi-celled organisms. FYPO_relaxed.owl CHEBI:70724 biolink:NamedThing cell dedifferentiation agent Any compound which induces a partially or terminally differentiated cell to revert to an earlier developmental stage. FYPO_relaxed.owl CHEBI:83317 biolink:NamedThing sterol biosynthesis inhibitor Any compound that inhibits the biosynthesis of any sterol. FYPO_relaxed.owl CHEBI:88230 biolink:NamedThing autophagy inhibitor Any compound that inhibits the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell). FYPO_relaxed.owl CHEBI:139048 biolink:NamedThing dihydroceramide An N-acylsphingoid obtained by formal condensation of the carboxy group of any fatty acid with the amino group of any dihydrosphingoid base. FYPO_relaxed.owl CHEBI:83273 biolink:NamedThing N-acylsphingoid A ceramide consisting of an undefined sphingoid base linked to an undefined fatty acid via an amide bond. FYPO_relaxed.owl CHEBI:139340 biolink:NamedThing 1,3-dihydroimidazole-2-thiones A member of the class of imidazoles that is 1,3-dihydroimidazole-2-thione and its derivatives by substitution. FYPO_relaxed.owl CHEBI:24780 biolink:NamedThing imidazoles A five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. FYPO_relaxed.owl CHEBI:16255 biolink:NamedThing L-histidinol An amino alcohol that is propanol substituted by 1H-imidazol-4-yl group at position 3 and an amino group at position 2 (the 2S stereoisomer). FYPO_relaxed.owl CHEBI:22512 biolink:NamedThing aminoimidazole Any member of the class of imidazoles carrying at least one amino substituent. FYPO_relaxed.owl CHEBI:27570 biolink:NamedThing histidine An alpha-amino acid that is propanoic acid bearing an amino substituent at position 2 and a 1H-imidazol-4-yl group at position 3. FYPO_relaxed.owl CHEBI:48117 biolink:NamedThing 1-glycosylimidazole FYPO_relaxed.owl CHEBI:76620 biolink:NamedThing S-methyl-L-ergothioneine An amino acid betaine that is ergothioneine in which the hydrogen attached to the sulfur is replaced by a methyl group. It has been isolated from the deepwater (500-1,600 m) marine sponge Macandrewia azorica. FYPO_relaxed.owl CHEBI:85619 biolink:NamedThing 4-amino-1-methylimidazole-5-carboselenoamide A member of the class of imidazoles bearing methyl, amino and selenocarboxamido substituents at positions 1, 4 and 5 respectively. FYPO_relaxed.owl CHEBI:86420 biolink:NamedThing imidazole antifungal agent A compound that has significant antifungal properties whose structure contains an imidazole moiety. FYPO_relaxed.owl CHEBI:51276 biolink:NamedThing thioureas Compounds of general formula RR'NC(=S)NR''R'''. FYPO_relaxed.owl CHEBI:70773 biolink:NamedThing capsazepine A benzazepine that is 2,3,4,5-tetrahydro-1H-2-benzazepine which is substituted by hydroxy groups at positions 7 and 8 and on the nitrogen atom by a 2-(p-chlorophenyl)ethylaminothiocarbonyl group. A synthetic analogue of capsaicin, it was the first reported capsaicin receptor antagonist. FYPO_relaxed.owl CHEBI:139358 biolink:NamedThing isotopically modified compound Any molecular entity in which the isotopic ratio of nuclides for at least one element deviates measurably from that occurring in nature. The term includes both isotopically substituted compounds (in which essentially all the molecules of the compound have only the indicated nuclide(s) at each designated position) and isotopically labeled compounds (a formal mixture of an isotopically unmodified compound with one or more analogous isotopically substituted compound(s). FYPO_relaxed.owl CHEBI:23367 biolink:NamedThing molecular entity Any constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer etc., identifiable as a separately distinguishable entity. FYPO_relaxed.owl CHEBI:24835 biolink:NamedThing inorganic molecular entity A molecular entity that contains no carbon. FYPO_relaxed.owl CHEBI:24870 biolink:NamedThing ion A molecular entity having a net electric charge. FYPO_relaxed.owl CHEBI:26519 biolink:NamedThing radical A molecular entity possessing an unpaired electron. FYPO_relaxed.owl CHEBI:33247 biolink:NamedThing organic group Any substituent group or skeleton containing carbon. FYPO_relaxed.owl CHEBI:33259 biolink:NamedThing elemental molecular entity A molecular entity all atoms of which have the same atomic number. FYPO_relaxed.owl CHEBI:33497 biolink:NamedThing transition element molecular entity A molecular entity containing one or more atoms of a transition element. FYPO_relaxed.owl CHEBI:35568 biolink:NamedThing mancude ring Any molecular entity that consists of a ring having (formally) the maximum number of noncumulative double bonds. FYPO_relaxed.owl CHEBI:36357 biolink:NamedThing polyatomic entity Any molecular entity consisting of more than one atom. FYPO_relaxed.owl CHEBI:13941 biolink:NamedThing carbamate FYPO_relaxed.owl CHEBI:49095 biolink:NamedThing beta-amino-acid anion FYPO_relaxed.owl CHEBI:61007 biolink:NamedThing amino fatty acid anion A nitrogen-containing fatty acid anion arising from deprotonation of the carboxy group of any amino fatty acid. FYPO_relaxed.owl CHEBI:63470 biolink:NamedThing sulfur-containing amino-acid anion A sulfur-containing amino acid whose alpha-carboxylic acid group is ionized (not protonated). FYPO_relaxed.owl CHEBI:63471 biolink:NamedThing branched-chain amino-acid anion A branched-chain amino acid whose alpha-carboxylic acid group is ionized. FYPO_relaxed.owl CHEBI:63473 biolink:NamedThing aromatic amino-acid anion An aromatic amino acid whose alpha-carboxylic acid group is ionized (non-protonated). FYPO_relaxed.owl CHEBI:52396 biolink:NamedThing alpha-oxyketone An oxyketone with the general formula R2C(=O) (R=/=H) where one or more of the R groups contains an oxy (-O-) group and the oxy and carbonyl groups are bonded to the same carbon atom. FYPO_relaxed.owl CHEBI:139592 biolink:NamedThing tertiary alpha-hydroxy ketone An alpha-hydroxy ketone in which the carbonyl group and the hydroxy group are linked by a carbon bearing two organyl groups. FYPO_relaxed.owl CHEBI:16831 biolink:NamedThing 3-hydroxy-3-methylglutaric acid A dicarboxylic acid that is glutaric acid in which one of the two hydrogens at position 3 is substituted by a hydroxy group, while the other is substituted by a methyl group. It has been found to accumulate in urine of patients suffering from HMG-CoA lyase (3-hydroxy-3-methylglutaryl-CoA lyase, EC 4.1.3.4) deficiency. It occurs as a plant metabolite in Crotalaria dura. FYPO_relaxed.owl CHEBI:27656 biolink:NamedThing camptothecin A pyranoindolizinoquinoline that is pyrano[3',4':6,7]indolizino[1,2-b]quinoline which is substituted by oxo groups at positions 3 and 14, and by an ethyl group and a hydroxy group at position 4 (the S enantiomer). FYPO_relaxed.owl CHEBI:46081 biolink:NamedThing fluconazole A member of the class of triazoles that is propan-2-ol substituted at position 1 and 3 by 1H-1,2,4-triazol-1-yl groups and at position 2 by a 2,4-difluorophenyl group. It is an antifungal drug used for the treatment of mucosal candidiasis and for systemic infections including systemic candidiasis, coccidioidomycosis, and cryptococcosis. FYPO_relaxed.owl CHEBI:78884 biolink:NamedThing 4-terpineol A terpineol that is 1-menthene carrying a hydroxy substituent at position 4. FYPO_relaxed.owl CHEBI:83779 biolink:NamedThing 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol A tertiary alcohol that is pentan-3-ol substituted by a 4-chlorophenyl, methyl, methyl, and a 1H-1,2,4-triazol-1-ylmethyl at positions 1, 4, 4 and 3 respectively. FYPO_relaxed.owl CHEBI:85085 biolink:NamedThing KT 5720 An organic heterooctacyclic compound that is 1H,1'H-2,2'-biindole in which the nitrogens have undergone formal oxidative coupling to positions 2 and 5 of hexyl (3S)-3-hydroxy-2-methyltetrahydrofuran-3-carboxylate (the 2R,3S,5S product), and in which the 3 and 3' positions of the biindole moiety have also undergone formal oxidative coupling to positions 3 and 4 of 1,5-dihydro-2H-pyrrol-2-one. FYPO_relaxed.owl CHEBI:140324 biolink:NamedThing primary carboxamide A carboxamide resulting from the formal condensation of a carboxylic acid with ammonia; formula RC(=O)NH2. FYPO_relaxed.owl CHEBI:140325 biolink:NamedThing secondary carboxamide A carboxamide resulting from the formal condensation of a carboxylic acid with a primary amine; formula RC(=O)NHR(1). FYPO_relaxed.owl CHEBI:16670 biolink:NamedThing peptide Amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another with formal loss of water. The term is usually applied to structures formed from alpha-amino acids, but it includes those derived from any amino carboxylic acid. X = OH, OR, NH2, NHR, etc. FYPO_relaxed.owl CHEBI:17761 biolink:NamedThing ceramide Ceramides (N-acyl-sphingoid bases) are a major subclass of sphingoid base derivatives with an amide-linked fatty acid. The fatty acids are typically saturated or monounsaturated with chain lengths from 14 to 26 carbon atoms; the presence of a hydroxyl group on carbon 2 is fairly common. Ceramides are generally precursors of more complex sphingolipids. In the illustrated generalised structure, R(1) = OH, OX (where X = acyl, glycosyl, phosphate, phosphonate, etc.), or H. FYPO_relaxed.owl CHEBI:22160 biolink:NamedThing acetamides Compounds with the general formula RNHC(=O)CH3. FYPO_relaxed.owl CHEBI:22475 biolink:NamedThing amino acid amide An amide of an amino acid formed formally by conversion of the carboxy group to a carboxamido group. FYPO_relaxed.owl CHEBI:23690 biolink:NamedThing dicarboxylic acid amide FYPO_relaxed.owl CHEBI:24079 biolink:NamedThing formamides Amides with the general formula R(1)R(2)NCHO (R(1) and R(2) can be H). FYPO_relaxed.owl CHEBI:24650 biolink:NamedThing hydroxamic acid A compound, RkE(=O)lNHOH, derived from an oxoacid RkE(=O)l(OH) (l =/= 0) by replacing -OH with -NHOH, and derivatives thereof. Specific examples of hydroxamic acids are preferably named as N-hydroxy amides. FYPO_relaxed.owl CHEBI:24995 biolink:NamedThing lactam Cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. FYPO_relaxed.owl CHEBI:25529 biolink:NamedThing pyridinecarboxamide A member of the class of pyridines that is a substituted pyridine in which at least one of the substituents is a carboxamide or N-substituted caraboxamide group. FYPO_relaxed.owl CHEBI:25848 biolink:NamedThing pantothenic acids A class of amides formed from pantoic acid and beta-alanine and its derivatives. FYPO_relaxed.owl CHEBI:29347 biolink:NamedThing monocarboxylic acid amide A carboxamide derived from a monocarboxylic acid. FYPO_relaxed.owl CHEBI:51569 biolink:NamedThing N-acyl-amino acid A carboxamide resulting from the formal condensation of a carboxylic acid with the amino group of an amino acid. FYPO_relaxed.owl CHEBI:51750 biolink:NamedThing alpha,beta-unsaturated carboxylic acid amide A monocarboxylic amide of general formula R(1)R(2)C=CR(3)-C(=O)NR(4)R(5) or R(1)C#C-C(=O)NR(2)R(3) in which the amide C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position. FYPO_relaxed.owl CHEBI:26208 biolink:NamedThing polyunsaturated fatty acid Any fatty acid containing more than one double bond. Acids in this group are reported to have cardioprotective effects; and levels are lowered in chronic fatigue syndrome. FYPO_relaxed.owl CHEBI:140359 biolink:NamedThing UDP-monosaccharide(2-) A nucleotide-sugar oxoanion obtained by deprotonation of the phosphate OH groups of any UDP-monosaccharide. This compound class represents generic and unspecified UDP-sugars. FYPO_relaxed.owl CHEBI:58439 biolink:NamedThing UDP-D-galactose(2-) A nucleotide-sugar oxoanion that is the dianion of UDP-D-galactose. FYPO_relaxed.owl CHEBI:78718 biolink:NamedThing UDP-alpha-D-glucosamine(1-) A nucleotide-sugar oxoanion that is the conjugate base of UDP-alpha-D-glucosamine, arising from deprotonation of the diphosphate group and protonation of the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:140601 biolink:NamedThing fatty acid 4:0 Any saturated fatty acid containing 4 carbons. FYPO_relaxed.owl CHEBI:26666 biolink:NamedThing short-chain fatty acid An aliphatic monocarboxylic acid with a chain length of less than C6. If any non-hydrocarbon substituent is present, the compound is not normally regarded as a short-chain fatty acid. FYPO_relaxed.owl CHEBI:17418 biolink:NamedThing valeric acid A straight-chain saturated fatty acid containing five carbon atoms. FYPO_relaxed.owl CHEBI:30768 biolink:NamedThing propionic acid A short-chain saturated fatty acid comprising ethane attached to the carbon of a carboxy group. FYPO_relaxed.owl CHEBI:38653 biolink:NamedThing methylbutyric acid A methyl-branched fatty acid comprising a butyric acid core carrying a single methyl substituent. FYPO_relaxed.owl CHEBI:140602 biolink:NamedThing Arabidopsis thaliana metabolite Any plant metabolite that is produced by Arabidopsis thaliana. FYPO_relaxed.owl CHEBI:76924 biolink:NamedThing plant metabolite Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms. FYPO_relaxed.owl CHEBI:27311 biolink:NamedThing volatile oil component Any plant metabolite that is found naturally as a component of a volatile oil. FYPO_relaxed.owl CHEBI:140948 biolink:NamedThing fatty acid 18:1 FYPO_relaxed.owl CHEBI:15904 biolink:NamedThing long-chain fatty acid A fatty acid with a chain length ranging from C13 to C22. FYPO_relaxed.owl CHEBI:26607 biolink:NamedThing saturated fatty acid Any fatty acid containing no carbon to carbon multiple bonds. Known to produce adverse biological effects when ingested to excess. FYPO_relaxed.owl CHEBI:27208 biolink:NamedThing unsaturated fatty acid Any fatty acid containing at least one C=C or C#C bond. FYPO_relaxed.owl CHEBI:27283 biolink:NamedThing very long-chain fatty acid A fatty acid which has a chain length greater than C22. Very long-chain fatty acids which have a chain length greater than C27 are also known as ultra-long-chain fatty acids. FYPO_relaxed.owl CHEBI:35819 biolink:NamedThing branched-chain fatty acid Any fatty acid in which the parent hydrocarbon chain has one or more alkyl substituents; a common component in animal and bacterial lipids. The fatty acyl chain is usually saturated and the substituent a methyl group; however, unsaturated BCFAs are found in marine animals, and branches other than methyl are found in microbial lipids. FYPO_relaxed.owl CHEBI:59202 biolink:NamedThing straight-chain fatty acid Any fatty acid whose skeletal carbon atoms form an unbranched open chain. FYPO_relaxed.owl CHEBI:59554 biolink:NamedThing medium-chain fatty acid Any fatty acid with a chain length of between C6 and C12. FYPO_relaxed.owl CHEBI:59644 biolink:NamedThing oxo fatty acid Any fatty acid containing at least one aldehydic or ketonic group in addition to the carboxylic acid group. FYPO_relaxed.owl CHEBI:60690 biolink:NamedThing nitrogen-containing fatty acid Any fatty acid containing nitrogen as either a substituent or a replacement for a methylene carbon. FYPO_relaxed.owl CHEBI:141668 biolink:NamedThing L-tyrosinal(1+) A primary ammonium ion resulting from the protonation of the amino group of L-tyrosinal. FYPO_relaxed.owl CHEBI:58001 biolink:NamedThing primary aliphatic ammonium ion The conjugate acid of a primary aliphatic amine. FYPO_relaxed.owl CHEBI:77452 biolink:NamedThing 2-deoxystreptamine cation An organic cation arising from protonation of the amino groups of any 2-deoxystreptamine antibiotic. FYPO_relaxed.owl CHEBI:83410 biolink:NamedThing alpha-amino acid ester(1+) A primary ammonium ion obtained by protonation of the amino group of any alpha-amino acid ester; major species at pH 7.3. FYPO_relaxed.owl CHEBI:142348 biolink:NamedThing hexahydronaphthalenes Any carbobycyclic compound that is an hexahydronaphthalene or a compound obtained from an hexahydronaphthalene by formal substitution of one or more hydrogens. FYPO_relaxed.owl CHEBI:36785 biolink:NamedThing carbobicyclic compound A bicyclic compound in which all the ring atoms are carbon. FYPO_relaxed.owl CHEBI:25477 biolink:NamedThing naphthalenes Any benzenoid aromatic compound having a skeleton composed of two ortho-fused benzene rings. FYPO_relaxed.owl CHEBI:35428 biolink:NamedThing ortho-fused bicyclic hydrocarbon FYPO_relaxed.owl CHEBI:46940 biolink:NamedThing indanes FYPO_relaxed.owl CHEBI:142355 biolink:NamedThing purines D-ribonucleoside A purine ribonucleoside that is a purine derivative attached to a beta-D-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage. FYPO_relaxed.owl CHEBI:26399 biolink:NamedThing purine ribonucleoside A ribonucleoside that has a purine moiety as the nucleobase (the R group in the illustration). FYPO_relaxed.owl CHEBI:22260 biolink:NamedThing adenosines Any purine ribonucleoside that is a derivative of adenosine. FYPO_relaxed.owl CHEBI:24844 biolink:NamedThing inosines Any purine ribonucleoside that is a derivative of inosine. FYPO_relaxed.owl CHEBI:142361 biolink:NamedThing purines 2'-deoxy-D-ribonucleoside A purine derivative attached to a beta-D-2'-deoxy-ribofuranosyl residue at position 9 via a glycosidic (N-glycosyl) linkage. FYPO_relaxed.owl CHEBI:19254 biolink:NamedThing purine 2'-deoxyribonucleoside A 2'-deoxyribonucleoside that has a purine moiety as the nucleobase (the R group in the illustration). FYPO_relaxed.owl CHEBI:142513 biolink:NamedThing oxime anion A organic ion resulting from the deprotonation of the hydroxy group of any oxime. FYPO_relaxed.owl CHEBI:25696 biolink:NamedThing organic anion Any organic ion with a net negative charge. FYPO_relaxed.owl CHEBI:142839 biolink:NamedThing enolate An organic anion arising from deprotonation of the hydroxy group of an enol. FYPO_relaxed.owl CHEBI:24648 biolink:NamedThing hydroxamic acid anion An oxoanion resulting from the removal of a proton from the hydroxy group of any hydroxamic acid. FYPO_relaxed.owl CHEBI:35604 biolink:NamedThing carbon oxoanion A negative ion consisting solely of carbon and oxygen atoms, and therefore having the general formula CxOy(n-) for some integers x, y and n. FYPO_relaxed.owl CHEBI:50525 biolink:NamedThing phenolate anion An organic anion arising from deprotonation of the OH function of a phenol compound. FYPO_relaxed.owl CHEBI:52090 biolink:NamedThing methoxide An organic anion that is the conjugate base of methanol. FYPO_relaxed.owl CHEBI:52092 biolink:NamedThing ethoxide An organic anion that is the conjugate base of ethanol. FYPO_relaxed.owl CHEBI:58958 biolink:NamedThing organosulfate oxoanion An organic anion of general formula RS(=O)2O(-) where R is an organyl group. FYPO_relaxed.owl CHEBI:59561 biolink:NamedThing diamino acid anion An organic anion that is the conjugate base of diamino acid. FYPO_relaxed.owl CHEBI:71392 biolink:NamedThing tetracycline(1-) An organic anion that is the conjugate base of tetracycline obtained by deprotonation of the two enolic hydroxy groups and protonation of the tertiary amino group. FYPO_relaxed.owl CHEBI:88190 biolink:NamedThing 2-oxido-5-methylquinone An organic anion obtained by deprotonation of the hydroxy group of 2-hydroxy-5-methylquinone. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). FYPO_relaxed.owl CHEBI:25235 biolink:NamedThing monomethoxybenzene Compounds containing a benzene skeleton substituted with one methoxy group. FYPO_relaxed.owl CHEBI:85615 biolink:NamedThing 2-bromo-1-(4-methoxyphenyl)-3-[(4-methylphenyl)sulfonyl]-1-propanone FYPO_relaxed.owl CHEBI:25409 biolink:NamedThing monoterpenoid Any terpenoid derived from a monoterpene. The term includes compounds in which the C10 skeleton of the parent monoterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). FYPO_relaxed.owl CHEBI:22912 biolink:NamedThing bornane monoterpenoid FYPO_relaxed.owl CHEBI:25186 biolink:NamedThing p-menthane monoterpenoid FYPO_relaxed.owl CHEBI:36054 biolink:NamedThing benzoate ester Esters of benzoic acid or substituted benzoic acids. FYPO_relaxed.owl CHEBI:142676 biolink:NamedThing ribozinoindole-1 A triazinoindole that is 5H-[1,2,4]triazino[5,6-b]indole which is substituted at position 3 by a (2-methylprop-2-en-1-yl)thio group. A potent inhibitor of midasin which is an essential protein for eukaryotic ribosome biogenesis. FYPO_relaxed.owl CHEBI:16385 biolink:NamedThing organic sulfide Compounds having the structure RSR (R =/= H). Such compounds were once called thioethers. FYPO_relaxed.owl CHEBI:16680 biolink:NamedThing S-adenosyl-L-homocysteine An organic sulfide that is the S-adenosyl derivative of L-homocysteine. FYPO_relaxed.owl CHEBI:27532 biolink:NamedThing L-cysteine thioether Any L-cysteine derivative obtained by conversion of the thiol group into a sulfide. FYPO_relaxed.owl CHEBI:68662 biolink:NamedThing S-ethylhomocysteine A non-proteinogenic alpha-amino acid that is methionine in which the S-methyl group is replaced by an S-ethyl group. FYPO_relaxed.owl CHEBI:79030 biolink:NamedThing S-adenosyl-3-thiopropylamine A thioadenosine that is adenosine in which the hydroxy group at C-5' is replaced by a 3-aminopropyl group. FYPO_relaxed.owl CHEBI:86315 biolink:NamedThing methyl sulfide Any aliphatic sulfide in which at least one of the organyl groups attached to the sulfur is a methyl group. FYPO_relaxed.owl CHEBI:90134 biolink:NamedThing S-adenosyl-L-cysteine An L-cysteine derivative in which the thiol hydrogen of L-cysteine is replaced by an adenosyl group. FYPO_relaxed.owl CHEBI:23527 biolink:NamedThing cytochalasin B An organic heterotricyclic compound, that is a mycotoxin which is cell permeable an an inhibitor of cytoplasmic division by blocking the formation of contractile microfilaments. FYPO_relaxed.owl CHEBI:36416 biolink:NamedThing mancude organic heterotricyclic parent FYPO_relaxed.owl CHEBI:38093 biolink:NamedThing phenothiazines FYPO_relaxed.owl CHEBI:38921 biolink:NamedThing pyridoquinoline FYPO_relaxed.owl CHEBI:39206 biolink:NamedThing dibenzopyridine FYPO_relaxed.owl CHEBI:569624 biolink:NamedThing papulacandin B A papulacandin that is papulacandin A in which the (2E,4E)-deca-2,4-dienoyl chain at the O-(6') position is replaced by a (2E,4Z,6E)-8-hydroxydeca-2,4,6-trienoyl chain. It is the major carbohydrate-containing antibiotic from the deuteromycetous fungus Papularia sphaerosperma which shows potent antifungal activity against Candida albicans. FYPO_relaxed.owl CHEBI:72630 biolink:NamedThing papulacandin D A papulacandin that is papulacandin A in which the 6-O-acylgalactosyl group is replaced by a hydrogen. It is a carbohydrate-containing antibiotic from the deuteromycetous fungus Papularia sphaerosperma which shows potent antifungal activity against Candida albicans. FYPO_relaxed.owl CHEBI:142967 biolink:NamedThing D-histidine zwitterion A polar amino acid zwitterion restulting from the transfer of a proton from the carboxy group to the alpha-amino group of D-histidine. The major species at pH 7.3. FYPO_relaxed.owl CHEBI:62031 biolink:NamedThing polar amino acid zwitterion Zwitterionic form of a polar amino acid having an anionic carboxy group and a protonated amino group. FYPO_relaxed.owl CHEBI:29985 biolink:NamedThing L-glutamate(1-) An alpha-amino-acid anion that is the conjugate base of L-glutamic acid, having anionic carboxy groups and a cationic amino group FYPO_relaxed.owl CHEBI:32551 biolink:NamedThing L-lysinium(1+) An optically active form of lysinium having L-configuration. FYPO_relaxed.owl CHEBI:46911 biolink:NamedThing L-ornithinium(1+) A polar amino acid zwitterion of L-ornithine. FYPO_relaxed.owl CHEBI:57595 biolink:NamedThing L-histidine zwitterion Zwitterionic form of L-histidine having an anionic carboxy group and a protonated alpha-amino group. FYPO_relaxed.owl CHEBI:58359 biolink:NamedThing L-glutamine zwitterion An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of L-glutamine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:143079 biolink:NamedThing D-leucine zwitterion A D-alpha-amino acid zwitterion arising from the transfer of a proton from the carboxy to the amino group of D-leucine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:59871 biolink:NamedThing D-alpha-amino acid zwitterion Zwitterionic form of a D-alpha-amino acid having an anionic carboxy group and a protonated amino group. FYPO_relaxed.owl CHEBI:143081 biolink:NamedThing D-homoserine zwitterion A D-alpha-amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of D-homoserine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57726 biolink:NamedThing D-proline zwitterion A D-alpha-amino acid zwitterion that is D-proline in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3. FYPO_relaxed.owl CHEBI:57757 biolink:NamedThing D-threonine zwitterion A D-alpha-amino acid zwitterion that is D-threonine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3. FYPO_relaxed.owl CHEBI:57981 biolink:NamedThing D-phenylalanine zwitterion A D-alpha-amino acid zwitterion that is D-phenylalanine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3. FYPO_relaxed.owl CHEBI:58570 biolink:NamedThing D-tyrosine zwitterion A D-alpha-amino acid zwitterion that is D-tyrosine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3. FYPO_relaxed.owl CHEBI:74337 biolink:NamedThing D-asparagine zwitterion A D-alpha-amino acid zwitterion that is D-asparagine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3. FYPO_relaxed.owl CHEBI:74338 biolink:NamedThing D-valine zwitterion A D-alpha-amino acid zwitterion that is D-valine in which a proton has been transferred from the carboxy group to the amino group. It is the major species at pH 7.3. FYPO_relaxed.owl CHEBI:143593 biolink:NamedThing beta-galactosylceramide FYPO_relaxed.owl CHEBI:36498 biolink:NamedThing galactosylceramide Any of the cerebrosides in which the monosaccharide head group is galactose. FYPO_relaxed.owl CHEBI:143813 biolink:NamedThing 1-radyl,2-acyl-sn-glycero-3-phospho-(1D-myo-2-acyl-inositol)(1-) A phosphatidylinositol where R1 can be an alkyl or an acyl chain and 2R2 is an acyl chain. FYPO_relaxed.owl CHEBI:50860 biolink:NamedThing organic molecular entity Any molecular entity that contains carbon. FYPO_relaxed.owl CHEBI:18059 biolink:NamedThing lipid 'Lipids' is a loosely defined term for substances of biological origin that are soluble in nonpolar solvents. They consist of saponifiable lipids, such as glycerides (fats and oils) and phospholipids, as well as nonsaponifiable lipids, principally steroids. FYPO_relaxed.owl CHEBI:194095 biolink:NamedThing mitomycin C(1-) FYPO_relaxed.owl CHEBI:194466 biolink:NamedThing L-Lysine zwitterion Primary zwitterion of L-Lysine present at the isoelectric point FYPO_relaxed.owl CHEBI:25699 biolink:NamedThing organic ion FYPO_relaxed.owl CHEBI:25707 biolink:NamedThing organometallic compound A compound having bonds between one or more metal atoms and one or more carbon atoms of an organyl group. FYPO_relaxed.owl CHEBI:25750 biolink:NamedThing oxime Compounds of structure R2C=NOH derived from condensation of aldehydes or ketones with hydroxylamine. Oximes from aldehydes may be called aldoximes; those from ketones may be called ketoximes. FYPO_relaxed.owl CHEBI:33245 biolink:NamedThing organic fundamental parent An organic fundamental parent is a structure used as a basis for substitutive names in organic nomenclature, containing, in addition to one or more hydrogen atoms, a single atom of an element, a number of atoms (alike or different) linked together to form an unbranched chain, a monocyclic or polycyclic ring system, or a ring assembly or ring/chain system. FYPO_relaxed.owl CHEBI:33285 biolink:NamedThing heteroorganic entity A heteroorganic entity is an organic molecular entity in which carbon atoms or organic groups are bonded directly to one or more heteroatoms. FYPO_relaxed.owl CHEBI:33653 biolink:NamedThing aliphatic compound Any acyclic or cyclic, saturated or unsaturated carbon compound, excluding aromatic compounds. FYPO_relaxed.owl CHEBI:33694 biolink:NamedThing biomacromolecule A macromolecule formed by a living organism. FYPO_relaxed.owl CHEBI:36606 biolink:NamedThing acid anhydride Compounds consisting of two acyl groups bonded to the same oxygen atom acyl-O-acyl. FYPO_relaxed.owl CHEBI:64708 biolink:NamedThing one-carbon compound An organic molecular entity containing a single carbon atom (C1). FYPO_relaxed.owl CHEBI:64709 biolink:NamedThing organic acid Any organic molecular entity that is acidic and contains carbon in covalent linkage. FYPO_relaxed.owl CHEBI:72544 biolink:NamedThing flavonoids Any organic molecular entity whose stucture is based on derivatives of a phenyl-substituted 1-phenylpropane possessing a C15 or C16 skeleton, or such a structure which is condensed with a C6-C3 lignan precursors. The term is a 'superclass' comprising all members of the classes of flavonoid, isoflavonoid, neoflavonoid, chalcones, dihydrochalcones, aurones, pterocarpan, coumestans, rotenoid, flavonolignan, homoflavonoid and flavonoid oligomers. Originally restricted to natural products, the term is also applied to synthetic compounds related to them. FYPO_relaxed.owl CHEBI:72588 biolink:NamedThing semisynthetic derivative Any organic molecular entity derived from a natural product by partial chemical synthesis. FYPO_relaxed.owl CHEBI:144644 biolink:NamedThing a tetracycline zwitterion FYPO_relaxed.owl CHEBI:26895 biolink:NamedThing tetracyclines A subclass of polyketides having an octahydrotetracene-2-carboxamide skeleton, substituted with many hydroxy and other groups. FYPO_relaxed.owl CHEBI:27902 biolink:NamedThing tetracycline A broad-spectrum polyketide antibiotic produced by the Streptomyces genus of actinobacteria. FYPO_relaxed.owl CHEBI:145545 biolink:NamedThing nitrosothio compound Any nitroso compound in which a carbon atom of an organyl group is attached to the sulfur atom of a nitrosothio group: R-S-N=O. FYPO_relaxed.owl CHEBI:33261 biolink:NamedThing organosulfur compound An organosulfur compound is a compound containing at least one carbon-sulfur bond. FYPO_relaxed.owl CHEBI:22063 biolink:NamedThing sulfoxide An organosulfur compound having the structure R2S=O or R2C=S=O (R =/= H). FYPO_relaxed.owl CHEBI:25230 biolink:NamedThing methionine derivative An amino acid derivative resulting from reaction of methionine at the amino group or the carboxy group, or from the replacement of any hydrogen of methionine by a heteroatom. The definition normally excludes peptides containing methionine residues. FYPO_relaxed.owl CHEBI:26953 biolink:NamedThing thioadenosine FYPO_relaxed.owl CHEBI:26959 biolink:NamedThing thiocarboxylic ester An ester in which one or both oxygens of an ester group have been replaced by divalent sulfur. FYPO_relaxed.owl CHEBI:29256 biolink:NamedThing thiol An organosulfur compound in which a thiol group, -SH, is attached to a carbon atom of any aliphatic or aromatic moiety. FYPO_relaxed.owl CHEBI:33551 biolink:NamedThing organosulfonic acid An organic derivative of sulfonic acid in which the sulfo group is linked directly to carbon. FYPO_relaxed.owl CHEBI:33576 biolink:NamedThing sulfur-containing carboxylic acid Any carboxylic acid having a sulfur substituent. FYPO_relaxed.owl CHEBI:35358 biolink:NamedThing sulfonamide An amide of a sulfonic acid RS(=O)2NR'2. FYPO_relaxed.owl CHEBI:35489 biolink:NamedThing organic disulfide Compounds of structure RSSR in which R and R' are organic groups. FYPO_relaxed.owl CHEBI:35850 biolink:NamedThing sulfone An organosulfur compound having the structure RS(=O)2R (R =/= H). FYPO_relaxed.owl CHEBI:38106 biolink:NamedThing organosulfur heterocyclic compound FYPO_relaxed.owl CHEBI:48544 biolink:NamedThing methanesulfonates Esters or salts of methanesulfonic acid. FYPO_relaxed.owl CHEBI:50492 biolink:NamedThing thiocarbonyl compound Any compound containing the thiocarbonyl group, C=S. FYPO_relaxed.owl CHEBI:35800 biolink:NamedThing nitroso compound Compounds having the nitroso group, -NO, attached to carbon, or to another element, most commonly nitrogen or oxygen. FYPO_relaxed.owl CHEBI:21759 biolink:NamedThing N-methyl-N'-nitro-N-nitrosoguanidine An N-nitroguanidine compound having nitroso and methyl substituents at the N'-position FYPO_relaxed.owl CHEBI:145556 biolink:NamedThing macrodiolide A macropolylide which contains two ester linkages in one macrocyclic ring. FYPO_relaxed.owl CHEBI:26789 biolink:NamedThing streptothricin An N-glycosyl compound consisting of 2-amino-4-O-carbamoyl-2-deoxy-N-[(3aS,7R,7aS)-7-hydroxy-4-oxooctahydro-2H-imidazo[4,5-c]pyridin-2-ylidene]-beta-D-gulopyranosylamine in which the amino group at position 2 of the gulopyranosyl moiety is acylated by a peptide unit made up of between 1 and 7 N(epsilon)-linked units of beta-lysine. FYPO_relaxed.owl CHEBI:74222 biolink:NamedThing gamma-lactam A lactam in which the amide bond is contained within a five-membered ring, which includes the amide nitrogen and the carbonyl carbon. FYPO_relaxed.owl CHEBI:145932 biolink:NamedThing (S)-2-methylbutanoate A branched-chain saturated fatty acid anion resulting from the deprotonation of the carboxy group of (S)-2-methylbutanoic acid. The major species at pH 7.3. FYPO_relaxed.owl CHEBI:58951 biolink:NamedThing short-chain fatty acid anion Any fatty acid anion obtained by removal of a proton from the carboxy group of a short-chain fatty acid (chain length of less than C6). FYPO_relaxed.owl CHEBI:17120 biolink:NamedThing hexanoate A short-chain fatty acid anion that is the conjugate base of hexanoic acid (also known as caproic acid). FYPO_relaxed.owl CHEBI:31011 biolink:NamedThing valerate A short-chain fatty acid anion that is the conjugate base of valeric acid; present in ester form as component of many steroid-based pharmaceuticals. FYPO_relaxed.owl CHEBI:48946 biolink:NamedThing 2-methylbutyrate FYPO_relaxed.owl CHEBI:78113 biolink:NamedThing fatty acid anion 3:0 Any saturated fatty acid anion containing 3 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. FYPO_relaxed.owl CHEBI:78115 biolink:NamedThing fatty acid anion 4:0 Any saturated fatty acid anion containing 4 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. FYPO_relaxed.owl CHEBI:58956 biolink:NamedThing branched-chain saturated fatty acid anion Any saturated fatty acid anion with a carbon side-chain or isopropyl termination. FYPO_relaxed.owl CHEBI:60654 biolink:NamedThing valproate A branched-chain saturated fatty acid anion that is the conjugate base of valproic acid. FYPO_relaxed.owl CHEBI:83976 biolink:NamedThing 2-methyl fatty acid anion A methyl-branched fatty acid anion obtained by deprotonation of the carboxy group of any 2-methyl fatty acid; major species at pH 7.3. FYPO_relaxed.owl CHEBI:145947 biolink:NamedThing antiatherosclerotic agent A cardiovascular drug that prevents atherosclerosis (a disease in which the inside of an artery narrows due to the build up of plaque). Compare with antiatherogenic agent. FYPO_relaxed.owl CHEBI:35620 biolink:NamedThing vasodilator agent A drug used to cause dilation of the blood vessels. FYPO_relaxed.owl CHEBI:38070 biolink:NamedThing anti-arrhythmia drug A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. FYPO_relaxed.owl CHEBI:147285 biolink:NamedThing EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor An EC 3.4.22.* (cysteine endopeptidase) inhibitor that interferes with the action of SARS coronavirus main proteinase (EC 3.4.22.69). FYPO_relaxed.owl CHEBI:76796 biolink:NamedThing EC 3.4.22.* (cysteine endopeptidase) inhibitor An EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the action of any cysteine endopeptidase (EC 3.4.22.*). FYPO_relaxed.owl CHEBI:147334 biolink:NamedThing 1-phosphatidyl-1D-myo-inositol anion derivative A phosphatidylinositol anion where the inositol is either not phosphorylated or phosphorylated at position 4 and/or position 5; major species at pH 7.3. FYPO_relaxed.owl CHEBI:147335 biolink:NamedThing 1-phosphatidyl-1D-myo-inositol-3-phosphate anion derivative A phosphatidylinositol anion where the inositol is phosphorylated at position 3 and either phosphorylated or not at position 4 and/or position 5; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57739 biolink:NamedThing phosphatidate(2-) An ionic phospholipid that is a dianion of a phosphatidic acid arising from deprotonation of both phosphate OH groups. FYPO_relaxed.owl CHEBI:60523 biolink:NamedThing phosphatidylglycerol(1-) An ionic phospholipid that is the organophosphate oxoanion formed from phosphatidylglycerol by removal of a proton from the phosphate OH group. FYPO_relaxed.owl CHEBI:64916 biolink:NamedThing inositol phosphoceramide(1-) An anionic phospholipid obtained by deprotonation of the free phosphate OH group of any inositol phosphoceramide; major species at pH 7.3. FYPO_relaxed.owl CHEBI:64997 biolink:NamedThing mannosylinositol phosphorylceramide(1-) An anionic phospholipid obtained by deprotonation of the phosphate OH group of any mannosylinositol phosphorylceramide; major species at pH 7.3. FYPO_relaxed.owl CHEBI:76529 biolink:NamedThing glycerophosphoglycerophosphoglycerol(2-) An anionic phospholipid composed of two molecules of glycerol phosphate covalently linked to a molecule of glycerol, and in which each of the glycerol phosphate moieties may be esterified to one or two fatty acids. FYPO_relaxed.owl CHEBI:76941 biolink:NamedThing sphingoid 1-phosphate(1-) A generic class of anionic phospholipids, encompassing phosphorylated derivatives of sphinganine, its homologues and stereoisomers, as well as the hydroxy and unsaturated derivatives of these compounds. FYPO_relaxed.owl CHEBI:78231 biolink:NamedThing 1,2-diacylglycero-3-phospho-1-inositol(1-) An anionic phospholipid that is the conjugate base of a 1,2-diacylglycero-3-phospho-1-inositol; major species at pH 7.3. FYPO_relaxed.owl CHEBI:78234 biolink:NamedThing monoacylglycero-3-phospho-1-inositol(1-) An anionic phospholipid obtained by deprotonation of the phosphate OH group of any monoacylglycero-3-phospho-1-inositol; major species at pH 7.3. FYPO_relaxed.owl CHEBI:83191 biolink:NamedThing phosphatidylinositol bisphosphate(5-) An anionic phospholipid obtained by deprotonation of the phospho groups of any phosphatidylinositol bisphosphate; major species at pH 7.3. FYPO_relaxed.owl CHEBI:83193 biolink:NamedThing phosphatidylinositol trisphosphate(7-) An anionic phospholipid obtained by deprotonation of the phospho groups of any phosphatidylinositol trisphosphate; major species at pH 7.3. FYPO_relaxed.owl CHEBI:149553 biolink:NamedThing anticoronaviral agent Any antiviral agent which inhibits the activity of coronaviruses. FYPO_relaxed.owl CHEBI:22587 biolink:NamedThing antiviral agent A substance that destroys or inhibits replication of viruses. FYPO_relaxed.owl CHEBI:36044 biolink:NamedThing antiviral drug A substance used in the prophylaxis or therapy of virus diseases. FYPO_relaxed.owl CHEBI:59897 biolink:NamedThing EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor A DNA polymerase inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need in order to reproduce. FYPO_relaxed.owl CHEBI:64946 biolink:NamedThing anti-HIV agent An antiviral agent that destroys or inhibits the replication of the human immunodeficiency virus. FYPO_relaxed.owl CHEBI:15022 biolink:NamedThing electron donor A molecular entity that can transfer an electron to another molecular entity. FYPO_relaxed.owl CHEBI:17891 biolink:NamedThing donor A molecular entity that can transfer ("donate") an electron, a pair of electrons, an atom or a group to another molecular entity. FYPO_relaxed.owl CHEBI:39144 biolink:NamedThing Lewis base A molecular entity able to provide a pair of electrons and thus capable of forming a covalent bond with an electron-pair acceptor (Lewis acid), thereby producing a Lewis adduct. FYPO_relaxed.owl CHEBI:50566 biolink:NamedThing nitric oxide donor An agent, with unique chemical structure and biochemical requirements, which generates nitric oxide. FYPO_relaxed.owl CHEBI:62049 biolink:NamedThing acyl donor Any donor that can transfer acyl groups between molecular entities. FYPO_relaxed.owl CHEBI:15075 biolink:NamedThing selenate A divalent inorganic anion obtained by removal of both protons from selenic acid. FYPO_relaxed.owl CHEBI:33488 biolink:NamedThing selenium oxoanion FYPO_relaxed.owl CHEBI:18212 biolink:NamedThing selenite(2-) FYPO_relaxed.owl CHEBI:29924 biolink:NamedThing hydrogenselenite FYPO_relaxed.owl CHEBI:33490 biolink:NamedThing hydrogenselenate FYPO_relaxed.owl CHEBI:79388 biolink:NamedThing divalent inorganic anion Any inorganic anion with a valency of two. FYPO_relaxed.owl CHEBI:15138 biolink:NamedThing sulfide(2-) A divalent inorganic anion obtained by removal of both protons from hydrogen sulfide. FYPO_relaxed.owl CHEBI:16189 biolink:NamedThing sulfate A sulfur oxoanion obtained by deprotonation of both OH groups of sulfuric acid. FYPO_relaxed.owl CHEBI:17359 biolink:NamedThing sulfite A sulfur oxoanion that is the conjugate base of hydrogen sulfite (H2SO3). FYPO_relaxed.owl CHEBI:29340 biolink:NamedThing hydridonitrate(2-) A divalent inorganic anion resulting from the removal of two protons from ammonia. FYPO_relaxed.owl CHEBI:35168 biolink:NamedThing hydrogenvanadate A divalent inorganic anion obtained by removal of two protons from vanadic acid. FYPO_relaxed.owl CHEBI:43474 biolink:NamedThing hydrogenphosphate A phosphate ion that is the conjugate base of dihydrogenphosphate. FYPO_relaxed.owl CHEBI:15318 biolink:NamedThing xanthine A purine nucleobase found in humans and other organisms. FYPO_relaxed.owl CHEBI:25810 biolink:NamedThing oxopurine FYPO_relaxed.owl CHEBI:16235 biolink:NamedThing guanine A 2-aminopurine carrying a 6-oxo substituent. FYPO_relaxed.owl CHEBI:17368 biolink:NamedThing hypoxanthine A purine nucleobase that consists of purine bearing an oxo substituent at position 6. FYPO_relaxed.owl CHEBI:26386 biolink:NamedThing purine nucleobase A nucleobase whose skeleton is derived from purine. FYPO_relaxed.owl CHEBI:16708 biolink:NamedThing adenine The parent compound of the 6-aminopurines, composed of a purine having an amino group at C-6. FYPO_relaxed.owl CHEBI:15339 biolink:NamedThing acceptor A molecular entity that can accept an electron, a pair of electrons, an atom or a group from another molecular entity. FYPO_relaxed.owl CHEBI:51086 biolink:NamedThing chemical role A role played by the molecular entity or part thereof within a chemical context. FYPO_relaxed.owl CHEBI:22586 biolink:NamedThing antioxidant A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. FYPO_relaxed.owl CHEBI:22695 biolink:NamedThing base A molecular entity having an available pair of electrons capable of forming a covalent bond with a hydron (Bronsted base) or with the vacant orbital of some other molecular entity (Lewis base). FYPO_relaxed.owl CHEBI:35223 biolink:NamedThing catalyst A substance that increases the rate of a reaction without modifying the overall standard Gibbs energy change in the reaction. FYPO_relaxed.owl CHEBI:37527 biolink:NamedThing acid An acid is a molecular entity capable of donating a hydron (Bronsted acid) or capable of forming a covalent bond with an electron pair (Lewis acid). FYPO_relaxed.owl CHEBI:52214 biolink:NamedThing ligand Any molecule or ion capable of binding to a central metal atom to form coordination complexes. FYPO_relaxed.owl CHEBI:62803 biolink:NamedThing fuel additive Any additive that enhances the efficiency of fuel. FYPO_relaxed.owl CHEBI:63046 biolink:NamedThing emulsifier The chemical role played by a substance that stabilizes an emulsion by increasing its kinetic stability. FYPO_relaxed.owl CHEBI:63247 biolink:NamedThing reducing agent The element or compound in a reduction-oxidation (redox) reaction that donates an electron to another species. FYPO_relaxed.owl CHEBI:63248 biolink:NamedThing oxidising agent A substance that removes electrons from another reactant in a redox reaction. FYPO_relaxed.owl CHEBI:63490 biolink:NamedThing explosive A substance capable of undergoing rapid and highly exothermic decomposition. FYPO_relaxed.owl CHEBI:76413 biolink:NamedThing greenhouse gas A gas in an atmosphere that absorbs and emits radiation within the thermal infrared range, so contributing to the 'greenhouse effect'. FYPO_relaxed.owl CHEBI:78298 biolink:NamedThing environmental contaminant Any minor or unwanted substance introduced into the environment that can have undesired effects. FYPO_relaxed.owl CHEBI:15343 biolink:NamedThing acetaldehyde The aldehyde formed from acetic acid by reduction of the carboxy group. It is the most abundant carcinogen in tobacco smoke. FYPO_relaxed.owl CHEBI:16842 biolink:NamedThing formaldehyde An aldehyde resulting from the formal oxidation of methanol. FYPO_relaxed.owl CHEBI:22492 biolink:NamedThing amino aldehyde Any aldehyde which contains an amino group. FYPO_relaxed.owl CHEBI:24960 biolink:NamedThing ketoaldehyde Any compound that has an aldehydic and ketonic group in the same molecule. FYPO_relaxed.owl CHEBI:25973 biolink:NamedThing phenylacetaldehydes FYPO_relaxed.owl CHEBI:26282 biolink:NamedThing propanals An aldehyde based on a propanal skeleton and its derivatives. FYPO_relaxed.owl CHEBI:38124 biolink:NamedThing dialdehyde Any aldehyde with two aldehyde groups. FYPO_relaxed.owl CHEBI:49104 biolink:NamedThing heteroarenecarbaldehyde An aldehyde in which a formyl group is located on a heteroarene. FYPO_relaxed.owl CHEBI:15346 biolink:NamedThing coenzyme A A thiol comprising a panthothenate unit in phosphoric anhydride linkage with a 3',5'-adenosine diphosphate unit; and an aminoethanethiol unit. FYPO_relaxed.owl CHEBI:37240 biolink:NamedThing adenosine 3',5'-bisphosphate FYPO_relaxed.owl CHEBI:17984 biolink:NamedThing acyl-CoA A thioester that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any carboxylic acid. FYPO_relaxed.owl CHEBI:15351 biolink:NamedThing acetyl-CoA An acyl-CoA having acetyl as its S-acetyl component. FYPO_relaxed.owl CHEBI:25136 biolink:NamedThing malonyl-CoAs Any short-chain fatty acyl-CoA in which the the fatty acid specified is malonic acid or its derivatives. FYPO_relaxed.owl CHEBI:37554 biolink:NamedThing fatty acyl-CoA An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any fatty acid. FYPO_relaxed.owl CHEBI:62618 biolink:NamedThing hydroxyacyl-CoA An acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any hydroxycarboxylic acid. FYPO_relaxed.owl CHEBI:15354 biolink:NamedThing choline A choline that is the parent compound of the cholines class, consisting of ethanolamine having three methyl substituents attached to the amino function. FYPO_relaxed.owl CHEBI:23217 biolink:NamedThing cholines A quaternary ammonium ion based on the choline ion and its substituted derivatives thereof. FYPO_relaxed.owl CHEBI:36700 biolink:NamedThing phosphocholines Any compound having phosphocholine as part of its structure. FYPO_relaxed.owl CHEBI:15356 biolink:NamedThing cysteine A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3. FYPO_relaxed.owl CHEBI:26167 biolink:NamedThing polar amino acid Any amino acid whose side chain is capable of forming one or more hydrogen bonds. FYPO_relaxed.owl CHEBI:17822 biolink:NamedThing serine An alpha-amino acid that is alanine substituted at position 3 by a hydroxy group. FYPO_relaxed.owl CHEBI:18186 biolink:NamedThing tyrosine An alpha-amino acid that is phenylalanine bearing a hydroxy substituent at position 4 on the phenyl ring. FYPO_relaxed.owl CHEBI:18237 biolink:NamedThing glutamic acid An alpha-amino acid that is glutaric acid bearing a single amino substituent at position 2. FYPO_relaxed.owl CHEBI:22653 biolink:NamedThing asparagine An alpha-amino acid in which one of the hydrogens attached to the alpha-carbon of glycine is substituted by a 2-amino-2-oxoethyl group. FYPO_relaxed.owl CHEBI:22660 biolink:NamedThing aspartic acid An alpha-amino acid that consists of succinic acid bearing a single alpha-amino substituent FYPO_relaxed.owl CHEBI:25094 biolink:NamedThing lysine A diamino acid that is caproic (hexanoic) acid bearing two amino substituents at positions 2 and 6. FYPO_relaxed.owl CHEBI:26986 biolink:NamedThing threonine An alpha-amino acid in which one of the hydrogens attached to the alpha-carbon of glycine is substituted by a 1-hydroxyethyl group. FYPO_relaxed.owl CHEBI:27897 biolink:NamedThing tryptophan An alpha-amino acid that is alanine bearing an indol-3-yl substituent at position 3. FYPO_relaxed.owl CHEBI:28300 biolink:NamedThing glutamine An alpha-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4. FYPO_relaxed.owl CHEBI:29016 biolink:NamedThing arginine An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group. FYPO_relaxed.owl CHEBI:26834 biolink:NamedThing sulfur-containing amino acid FYPO_relaxed.owl CHEBI:16811 biolink:NamedThing methionine A sulfur-containing amino acid that is butyric acid bearing an amino substituent at position 2 and a methylthio substituent at position 4. FYPO_relaxed.owl CHEBI:17230 biolink:NamedThing homocysteine A sulfur-containing amino acid consisting of a glycine core with a 2-mercaptoethyl side-chain. FYPO_relaxed.owl CHEBI:47910 biolink:NamedThing S-substituted L-cysteine FYPO_relaxed.owl CHEBI:4828 biolink:NamedThing ergothioneine A L-histidine derivative that is N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a mercapto group. A naturally occurring metabolite of histidine synthesized by bacteria and fungi with antioxidant properties. It is found ubiquitously in plants and animals and is present in many human foodstuffs. FYPO_relaxed.owl CHEBI:33704 biolink:NamedThing alpha-amino acid An amino acid in which the amino group is located on the carbon atom at the position alpha to the carboxy group. FYPO_relaxed.owl CHEBI:15705 biolink:NamedThing L-alpha-amino acid Any alpha-amino acid having L-configuration at the alpha-carbon. FYPO_relaxed.owl CHEBI:16449 biolink:NamedThing alanine An alpha-amino acid that consists of propionic acid bearing an amino substituent at position 2. FYPO_relaxed.owl CHEBI:25017 biolink:NamedThing leucine A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group. FYPO_relaxed.owl CHEBI:26271 biolink:NamedThing proline An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2. FYPO_relaxed.owl CHEBI:27266 biolink:NamedThing valine A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isopropyl group. FYPO_relaxed.owl CHEBI:28044 biolink:NamedThing phenylalanine An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group. FYPO_relaxed.owl CHEBI:38263 biolink:NamedThing 2-amino-3-hydroxybutanoic acid An alpha-amino acid that is butanoic acid substituted by an amino group at position 2 and a hydroxy group at position 3. FYPO_relaxed.owl CHEBI:38264 biolink:NamedThing 2-amino-3-methylpentanoic acid A branched chain amino acid that consists of 3-methylpentanoic acid bearing an amino substituent at position 2. FYPO_relaxed.owl CHEBI:83925 biolink:NamedThing non-proteinogenic alpha-amino acid Any alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids. FYPO_relaxed.owl CHEBI:15369 biolink:NamedThing actinomycin A large group of antibiotics isolated from various species of Streptomyces and characterised by having a substituted phenoxazine ring linked to two cyclic heterodetic peptides. FYPO_relaxed.owl CHEBI:23239 biolink:NamedThing chromopeptide FYPO_relaxed.owl CHEBI:15377 biolink:NamedThing water An oxygen hydride consisting of an oxygen atom that is covalently bonded to two hydrogen atoms FYPO_relaxed.owl CHEBI:33693 biolink:NamedThing oxygen hydride FYPO_relaxed.owl CHEBI:16234 biolink:NamedThing hydroxide FYPO_relaxed.owl CHEBI:29192 biolink:NamedThing hydrogenperoxide(1-) FYPO_relaxed.owl CHEBI:29412 biolink:NamedThing oxonium FYPO_relaxed.owl CHEBI:37176 biolink:NamedThing mononuclear parent hydride FYPO_relaxed.owl CHEBI:16134 biolink:NamedThing ammonia An azane that consists of a single nitrogen atom covelently bonded to three hydrogen atoms. FYPO_relaxed.owl CHEBI:16136 biolink:NamedThing hydrogen sulfide A sulfur hydride consisting of a single sulfur atom bonded to two hydrogen atoms. A highly poisonous, flammable gas with a characteristic odour of rotten eggs, it is often produced by bacterial decomposition of organic matter in the absence of oxygen. FYPO_relaxed.owl CHEBI:17883 biolink:NamedThing hydrogen chloride A mononuclear parent hydride consisting of covalently bonded hydrogen and chlorine atoms. FYPO_relaxed.owl CHEBI:29228 biolink:NamedThing hydrogen fluoride A diatomic molecule containing covalently bonded hydrogen and fluorine atoms. FYPO_relaxed.owl CHEBI:47266 biolink:NamedThing hydrogen bromide A diatomic molecule containing covalently bonded hydrogen and bromine atoms. FYPO_relaxed.owl CHEBI:52625 biolink:NamedThing inorganic hydroxy compound FYPO_relaxed.owl CHEBI:15393 biolink:NamedThing (+)-borneol FYPO_relaxed.owl CHEBI:28093 biolink:NamedThing borneol A bornane monoterpenoid that is 1,7,7-trimethylbicyclo[2.2.1]heptane substituted by a hydroxy group at position 2. FYPO_relaxed.owl CHEBI:15394 biolink:NamedThing (-)-borneol FYPO_relaxed.owl CHEBI:15414 biolink:NamedThing S-adenosyl-L-methionine A sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine. FYPO_relaxed.owl CHEBI:26830 biolink:NamedThing sulfonium compound FYPO_relaxed.owl CHEBI:156255 biolink:NamedThing S-adenosyl-D-methionine FYPO_relaxed.owl CHEBI:30488 biolink:NamedThing sulfonium FYPO_relaxed.owl CHEBI:35282 biolink:NamedThing sulfonium betaine Neutral molecules having charge-separated forms with an sulfonium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom. FYPO_relaxed.owl CHEBI:15428 biolink:NamedThing glycine The simplest (and the only achiral) proteinogenic amino acid, with a hydrogen atom as its side chain. FYPO_relaxed.owl CHEBI:26650 biolink:NamedThing serine family amino acid An L-alpha-amino acid which is biosynthesised from 3-phosphoglycerate (i.e. serine, glycine, cysteine and homocysteine). A closed class. FYPO_relaxed.owl CHEBI:17115 biolink:NamedThing L-serine The L-enantiomer of serine. FYPO_relaxed.owl CHEBI:17561 biolink:NamedThing L-cysteine An optically active form of cysteine having L-configuration. FYPO_relaxed.owl CHEBI:15429 biolink:NamedThing hydroxylamine The simplest hydroxylamine, consisting of ammonia bearing a hydroxy substituent. It is an intermediate in the biological nitrification by microbes like bacteria. FYPO_relaxed.owl CHEBI:24709 biolink:NamedThing hydroxylamines Hydroxylamine, H2N-OH, and its hydrocarbyl derivatives. FYPO_relaxed.owl CHEBI:15440 biolink:NamedThing squalene A triterpene consisting of 2,6,10,15,19,23-hexamethyltetracosane having six double bonds at the 2-, 6-, 10-, 14-, 18- and 22-positions with (all-E)-configuration. FYPO_relaxed.owl CHEBI:35191 biolink:NamedThing triterpene A C30 terpene. FYPO_relaxed.owl CHEBI:20265 biolink:NamedThing lanostane FYPO_relaxed.owl CHEBI:15524 biolink:NamedThing glutaryl-CoA An omega-carboxyacyl-CoA that results from the formal condensation of the thiol group of coenzyme A with one of the carboxy groups of glutaric acid. FYPO_relaxed.owl CHEBI:15531 biolink:NamedThing malonyl-CoA The S-malonyl derivative of coenzyme A. FYPO_relaxed.owl CHEBI:15570 biolink:NamedThing D-alanine The D-enantiomer of alanine. FYPO_relaxed.owl CHEBI:16977 biolink:NamedThing L-alanine The L-enantiomer of alanine. FYPO_relaxed.owl CHEBI:16733 biolink:NamedThing D-alpha-amino acid FYPO_relaxed.owl CHEBI:15816 biolink:NamedThing D-arginine A D-alpha-amino acid that is the D-isomer of arginine. FYPO_relaxed.owl CHEBI:15966 biolink:NamedThing D-glutamic acid An optically active form of glutamic acid having D-configuration. FYPO_relaxed.owl CHEBI:16176 biolink:NamedThing D-ornithine The D-enantiomer of ornithine. It is an intermediate metabolite produced in the urea cycle. FYPO_relaxed.owl CHEBI:16296 biolink:NamedThing D-tryptophan The D-enantiomer of tryptophan. FYPO_relaxed.owl CHEBI:16313 biolink:NamedThing D-proline The D-enantiomer of proline. FYPO_relaxed.owl CHEBI:16375 biolink:NamedThing D-cysteine An optically active form of cysteine having D-configuration. FYPO_relaxed.owl CHEBI:16398 biolink:NamedThing D-threonine An optically active form of threonine having D-configuration. FYPO_relaxed.owl CHEBI:16523 biolink:NamedThing D-serine The R-enantiomer of serine. FYPO_relaxed.owl CHEBI:16855 biolink:NamedThing D-lysine The D-enantiomer of the alpha-amino acid lysine. FYPO_relaxed.owl CHEBI:16867 biolink:NamedThing D-methionine An optically active form of methionine having D-configuration. FYPO_relaxed.owl CHEBI:16998 biolink:NamedThing D-phenylalanine The D-enantiomer of phenylalanine. FYPO_relaxed.owl CHEBI:17061 biolink:NamedThing D-glutamine The D-enantiomer of glutamine. FYPO_relaxed.owl CHEBI:17364 biolink:NamedThing D-aspartic acid The D-enantiomer of aspartic acid. FYPO_relaxed.owl CHEBI:27477 biolink:NamedThing D-valine The D-enantiomer of valine. FYPO_relaxed.owl CHEBI:27730 biolink:NamedThing D-isoleucine The D-enantiomer of isoleucine. FYPO_relaxed.owl CHEBI:27947 biolink:NamedThing D-histidine An optically active form of histidine having D-configuration. FYPO_relaxed.owl CHEBI:28159 biolink:NamedThing D-asparagine An optically active form of asparagine having D-configuration. FYPO_relaxed.owl CHEBI:28225 biolink:NamedThing D-leucine The D-enantiomer of leucine. FYPO_relaxed.owl CHEBI:28479 biolink:NamedThing D-tyrosine An optically active form of tyrosine having D-configuration. FYPO_relaxed.owl CHEBI:30654 biolink:NamedThing D-homoserine The D-enantiomer of homoserine. FYPO_relaxed.owl CHEBI:155837 biolink:NamedThing tripeptide zwitterion A peptide zwitterion obtained from the tranfer of a proton from the carboxy group to the amino group of any tripeptide. It contains an equal number of positively-charged and negatively-charged functional groups. Major structure at pH 7.3. FYPO_relaxed.owl CHEBI:60466 biolink:NamedThing peptide zwitterion Zwitterionic form of any peptide where, in general, the amino terminus is positively charged and the carboxy terminus is negatively charged. FYPO_relaxed.owl CHEBI:90799 biolink:NamedThing dipeptide zwitterion Any peptide zwitterion comprising two amino acid residues. Major structure at pH 7.3. FYPO_relaxed.owl CHEBI:15603 biolink:NamedThing L-leucine The L-enantiomer of leucine. FYPO_relaxed.owl CHEBI:26463 biolink:NamedThing pyruvate family amino acid An L-alpha-amino acid which is biosynthesised from pyruvate (i.e. alanine, valine, and leucine). A closed class. FYPO_relaxed.owl CHEBI:16414 biolink:NamedThing L-valine The L-enantiomer of valine. FYPO_relaxed.owl CHEBI:156132 biolink:NamedThing L-thialysinium Major microspecies at pH 7.3. FYPO_relaxed.owl CHEBI:15693 biolink:NamedThing aldose Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals. FYPO_relaxed.owl CHEBI:35381 biolink:NamedThing monosaccharide Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group. FYPO_relaxed.owl CHEBI:18133 biolink:NamedThing hexose Any six-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldohexose) or a ketone group at position 2 (ketohexose). FYPO_relaxed.owl CHEBI:24978 biolink:NamedThing ketose Ketonic parent sugars (polyhydroxy ketones H[CH(OH)]nC(=O)[CH(OH)]mH) and their intramolecular hemiketals. FYPO_relaxed.owl CHEBI:25901 biolink:NamedThing pentose A five-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldopentose) or a ketone group at position 2 (ketopentose). FYPO_relaxed.owl CHEBI:27137 biolink:NamedThing triose A monosaccharide containing three carbon atoms, which is important in respiration. Only two trioses occur naturally: the aldotriose glyceraldehyde and the ketotriose dihydroxyacetone. FYPO_relaxed.owl CHEBI:33905 biolink:NamedThing heptose A seven-carbon monosaccharide which in its linear form contains either an aldehyde group at position 1 (aldoheptose) or a ketone group at position 2 (ketoheptose). FYPO_relaxed.owl CHEBI:15699 biolink:NamedThing L-homoserine The L-enantiomer of homoserine. FYPO_relaxed.owl CHEBI:30653 biolink:NamedThing homoserine An alpha-amino acid that is glycine substituted at the alpha-position by a 2-hydroxyethyl group. FYPO_relaxed.owl CHEBI:15721 biolink:NamedThing sedoheptulose 7-phosphate A ketoheptose phosphate consisting of sedoheptulose having a phosphate group at the 7-position. It is an intermediate metabolite in the pentose phosphate pathway. FYPO_relaxed.owl CHEBI:35133 biolink:NamedThing ketoheptose phosphate FYPO_relaxed.owl CHEBI:63403 biolink:NamedThing sedoheptulose derivative A ketoheptose derivative that is formally obtained from sedoheptulose. FYPO_relaxed.owl CHEBI:15729 biolink:NamedThing L-ornithine An optically active form of ornithine having L-configuration. FYPO_relaxed.owl CHEBI:18257 biolink:NamedThing ornithine An alpha-amino acid that is pentanoic acid bearing two amino substituents at positions 2 and 5. FYPO_relaxed.owl CHEBI:83822 biolink:NamedThing non-proteinogenic L-alpha-amino acid Any L-alpha-amino acid which is not a member of the group of 23 proteinogenic amino acids. FYPO_relaxed.owl CHEBI:21752 biolink:NamedThing N-methyl-L-alpha-amino acid An non-proteinogenic L-alpha-amino acid in which the amino group bears one or more methyl groups. FYPO_relaxed.owl CHEBI:497734 biolink:NamedThing L-thialysine A cysteine derivative that is the S-(2-aminoethyl) analogue of L-cysteine; reported to have cytotoxic effects. FYPO_relaxed.owl CHEBI:609827 biolink:NamedThing L-canavanine A non-proteinogenic L-alpha-amino acid that is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group. Although structurally related to L-arginine, it is non-proteinogenic. FYPO_relaxed.owl CHEBI:15738 biolink:NamedThing staurosporine FYPO_relaxed.owl CHEBI:37697 biolink:NamedThing indolocarbazole alkaloid FYPO_relaxed.owl CHEBI:43616 biolink:NamedThing K-252a A organic heterooctacyclic compound that is a potent inhibitor of protein kinase C and is isolated from Nocardiopsis sp K-252a FYPO_relaxed.owl CHEBI:15740 biolink:NamedThing formate A monocarboxylic acid anion that is the conjugate base of formic acid. Induces severe metabolic acidosis and ocular injury in human subjects. FYPO_relaxed.owl CHEBI:16454 biolink:NamedThing pantothenate A monocarboxylic acid anion that is the conjugate base of pantothenic acid, obtained by deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:18021 biolink:NamedThing phosphoenolpyruvate A monocarboxylic acid anion resuting from selective deprotonation of the carboxy group of phosphoenolpyruvic acid. FYPO_relaxed.owl CHEBI:22299 biolink:NamedThing aldonate A monocarboxylic acid anion resulting from the deprotonation of the carboxy group of an aldonic acid. FYPO_relaxed.owl CHEBI:22718 biolink:NamedThing benzoates A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any benzoic acid. FYPO_relaxed.owl CHEBI:28868 biolink:NamedThing fatty acid anion The conjugate base of a fatty acid, arising from deprotonation of the carboxylic acid group of the corresponding fatty acid. FYPO_relaxed.owl CHEBI:29749 biolink:NamedThing ferulate A monocarboxylic acid anion obtained by the deprotonation of the carboxy group of ferulic acid. FYPO_relaxed.owl CHEBI:30089 biolink:NamedThing acetate A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of acetic acid. FYPO_relaxed.owl CHEBI:36059 biolink:NamedThing hydroxy monocarboxylic acid anion Any monocarboxylic acid anion carrying at least one hydroxy substituent. FYPO_relaxed.owl CHEBI:37080 biolink:NamedThing acrylate FYPO_relaxed.owl CHEBI:38181 biolink:NamedThing pyridinemonocarboxylate A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of a pyridinemonocarboxylic acid. A 'closed class'. FYPO_relaxed.owl CHEBI:38439 biolink:NamedThing N-acetyl-D-glucosaminate A monocarboxylic acid anion resulting from deprotonation of the carboxy group of N-acetyl-D-glucosaminic acid; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57586 biolink:NamedThing biotinate Conjugate base of biotin arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:62070 biolink:NamedThing nalidixic acid anion A monocarboxylic acid anion that is the conjugate base of nalidixic acid; major species at pH 7.3. FYPO_relaxed.owl CHEBI:62932 biolink:NamedThing mycophenolate A monocarboxylic acid anion resulting from the removal of a proton from the carboxy group of mycophenolic acid. FYPO_relaxed.owl CHEBI:63660 biolink:NamedThing pravastatin(1-) A monocarboxylic acid anion resulting from the deprotonation of the carboxylic acid group of pravastatin. FYPO_relaxed.owl CHEBI:77450 biolink:NamedThing dicarboxylic acid monoamide(1-) A monocarboxylic acid anion obtained by deprotonation of the carboxy group of any dicarboxylic acid monoamide; major species at pH 7.3. FYPO_relaxed.owl CHEBI:15741 biolink:NamedThing succinic acid An alpha,omega-dicarboxylic acid resulting from the formal oxidation of each of the terminal methyl groups of butane to the corresponding carboxy group. It is an intermediate metabolite in the citric acid cycle. FYPO_relaxed.owl CHEBI:28383 biolink:NamedThing alpha,omega-dicarboxylic acid FYPO_relaxed.owl CHEBI:17859 biolink:NamedThing glutaric acid An alpha,omega-dicarboxylic acid that is a linear five-carbon dicarboxylic acid. FYPO_relaxed.owl CHEBI:9300 biolink:NamedThing suberic acid An alpha,omega-dicarboxylic acid that is the 1,6-dicarboxy derivative of hexane. FYPO_relaxed.owl CHEBI:66873 biolink:NamedThing C4-dicarboxylic acid Any dicarboxylic acid that contains four carbon atoms. FYPO_relaxed.owl CHEBI:22958 biolink:NamedThing butenedioic acid FYPO_relaxed.owl CHEBI:157763 biolink:NamedThing polyprenol phosphate anion A polyprenol phosphate in which the hydroxyl hydrogen is replaced by a phospho group, major species at pH 7.3. FYPO_relaxed.owl CHEBI:26199 biolink:NamedThing polyprenol Any member of the class of prenols possessing the general formula H-[CH2C(Me)=CHCH2]nOH in which the carbon skeleton is composed of more than one isoprene units. FYPO_relaxed.owl CHEBI:157775 biolink:NamedThing N-acyl-beta-D-galactosylphytosphingosine FYPO_relaxed.owl CHEBI:21575 biolink:NamedThing N-acetyl-amino acid An N-acyl-amino acid that has acetyl as the acyl group. FYPO_relaxed.owl CHEBI:21644 biolink:NamedThing N-acyl-L-amino acid Any N-acylamino acid having L-configuration. FYPO_relaxed.owl CHEBI:15781 biolink:NamedThing N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine FYPO_relaxed.owl CHEBI:21911 biolink:NamedThing N(alpha)-methyl-L-histidines A N-methyl-L-alpha-amino acid that is L-histidine in which at least one of the amino hydrogens has been replaced by a methyl group. FYPO_relaxed.owl CHEBI:16029 biolink:NamedThing N(alpha),N(alpha)-dimethyl-L-histidine The N(alpha),N(alpha)-dimethyl derivative of L-histidine. FYPO_relaxed.owl CHEBI:22860 biolink:NamedThing amino-acid betaine Any amino acid-derived zwitterion - such as glycine betaine (N,N,N-trimethylammonioacetate) - in which the ammonium nitrogen carries methyl substituents and bears no hydrogen atoms. FYPO_relaxed.owl CHEBI:79071 biolink:NamedThing selenoneine A histidine derivative that is N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine substituted by a selenoxo group at position 2 on the imidazole ring. A selenium-containing antioxidant found in tuna blood. FYPO_relaxed.owl CHEBI:82707 biolink:NamedThing ergothioneine thione form A L-histidine derivative that is N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine in which the hydrogen at position 2 on the imdazole ring is replaced by a thioxo group. FYPO_relaxed.owl CHEBI:16467 biolink:NamedThing L-arginine An L-alpha-amino acid that is the L-isomer of arginine. FYPO_relaxed.owl CHEBI:15824 biolink:NamedThing D-fructose Fructose is a levorotatory monosaccharide and an isomer of glucose. Although fructose is a hexose (6 carbon sugar), it generally exists as a 5-member hemiketal ring (a furanose). FYPO_relaxed.owl CHEBI:28757 biolink:NamedThing fructose A ketohexose that is an isomer of glucose. FYPO_relaxed.owl CHEBI:15831 biolink:NamedThing geranylgeranyl diphosphate A polyprenol diphosphate having geranylgeranyl as the polyprenyl component. FYPO_relaxed.owl CHEBI:37531 biolink:NamedThing polyprenyl diphosphate FYPO_relaxed.owl CHEBI:50277 biolink:NamedThing farnesyl diphosphate FYPO_relaxed.owl CHEBI:15841 biolink:NamedThing polypeptide A peptide containing ten or more amino acid residues. FYPO_relaxed.owl CHEBI:23449 biolink:NamedThing cyclic peptide FYPO_relaxed.owl CHEBI:23643 biolink:NamedThing depsipeptide A natural or synthetic compound having a sequence of amino and hydroxy carboxylic acid residues (usually alpha-amino and alpha-hydroxy acids), commonly but not necessarily regularly alternating. FYPO_relaxed.owl CHEBI:24396 biolink:NamedThing glycopeptide Any carbohydrate derivative that consists of glycan moieties covalently attached to the side chains of the amino acid residues that constitute the peptide. FYPO_relaxed.owl CHEBI:25676 biolink:NamedThing oligopeptide A peptide containing a relatively small number of amino acids. FYPO_relaxed.owl CHEBI:25903 biolink:NamedThing peptide antibiotic A chemically diverse class of peptides that exhibit antimicrobial properties. FYPO_relaxed.owl CHEBI:25905 biolink:NamedThing peptide hormone Any peptide with hormonal activity in animals, whether endocrine, neuroendocrine, or paracrine. FYPO_relaxed.owl CHEBI:38579 biolink:NamedThing peptide pheromone FYPO_relaxed.owl CHEBI:46895 biolink:NamedThing lipopeptide A compound consisting of a peptide with attached lipid. FYPO_relaxed.owl CHEBI:60836 biolink:NamedThing phytochelatin A family of peptides related to glutathione and composed of (gamma-Glu-Cys)n-Gly where n is in the range 2-11. FYPO_relaxed.owl CHEBI:33839 biolink:NamedThing macromolecule A macromolecule is a molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. FYPO_relaxed.owl CHEBI:15842 biolink:NamedThing orotidine 5'-phosphate A pyrimidine ribonucleoside 5'-monophosphate having 6-carboxyuracil as the nucleobase. FYPO_relaxed.owl CHEBI:39457 biolink:NamedThing pyrimidine ribonucleoside 5'-monophosphate FYPO_relaxed.owl CHEBI:16695 biolink:NamedThing uridine 5'-monophosphate A pyrimidine ribonucleoside 5'-monophosphate having uracil as the nucleobase. FYPO_relaxed.owl CHEBI:15858 biolink:NamedThing bromide FYPO_relaxed.owl CHEBI:16042 biolink:NamedThing halide anion A monoatomic monoanion resulting from the addition of an electron to any halogen atom. FYPO_relaxed.owl CHEBI:17051 biolink:NamedThing fluoride FYPO_relaxed.owl CHEBI:17996 biolink:NamedThing chloride A halide anion formed when chlorine picks up an electron to form an an anion. FYPO_relaxed.owl CHEBI:36896 biolink:NamedThing monoatomic bromine FYPO_relaxed.owl CHEBI:15866 biolink:NamedThing 2-deoxy-D-glucose A deoxyglucose that is D-glucose in which the hydroxy group at position 2 has been replaced by a hydrogen. It is an antimetabolite of glucose with antiviral activity, which acts by inhibiting the glycosylation of glycoproteins and glycolipids. Used as an antiherpes agent. FYPO_relaxed.owl CHEBI:23623 biolink:NamedThing deoxyglucose A deoxyhexose comprising glucose having at least one hydroxy group replaced by hydrogen. FYPO_relaxed.owl CHEBI:15889 biolink:NamedThing sterol Any 3-hydroxy steroid whose skeleton is closely related to cholestan-3-ol (additional carbon atoms may be present in the side chain). FYPO_relaxed.owl CHEBI:36834 biolink:NamedThing 3-hydroxy steroid Any hydroxy steroid carrying a hydroxy group at position 3. FYPO_relaxed.owl CHEBI:15903 biolink:NamedThing beta-D-glucose D-Glucopyranose with beta configuration at the anomeric centre. FYPO_relaxed.owl CHEBI:4167 biolink:NamedThing D-glucopyranose A glucopyranose having D-configuration. FYPO_relaxed.owl CHEBI:15926 biolink:NamedThing dolichyl diphosphooligosaccharide FYPO_relaxed.owl CHEBI:26186 biolink:NamedThing polyprenyl phospho oligosaccharide FYPO_relaxed.owl CHEBI:15940 biolink:NamedThing nicotinic acid A pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group. FYPO_relaxed.owl CHEBI:176839 biolink:NamedThing vitamin B3 Any member of a group of vitamers that belong to the chemical structural class called pyridines that exhibit biological activity against vitamin B3 deficiency. Vitamin B3 deficiency causes a condition known as pellagra whose symptoms include depression, dermatitis and diarrhea. The vitamers include nicotinic acid and nicotinamide (and their ionized and salt forms). FYPO_relaxed.owl CHEBI:17154 biolink:NamedThing nicotinamide A pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. FYPO_relaxed.owl CHEBI:32544 biolink:NamedThing nicotinate A pyridinemonocarboxylate that is the conjugate base of nicotinic acid, arising from deprotonation of the carboxy group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:26416 biolink:NamedThing pyridine alkaloid FYPO_relaxed.owl CHEBI:15956 biolink:NamedThing biotin An organic heterobicyclic compound that consists of 2-oxohexahydro-1H-thieno[3,4-d]imidazole having a valeric acid substituent attached to the tetrahydrothiophene ring. The parent of the class of biotins. FYPO_relaxed.owl CHEBI:176841 biolink:NamedThing vitamin B7 Any member of a group of vitamers that belong to the chemical structural class called biotins that exhibit biological activity against vitamin B7 deficiency. Vitamin B7 deficiency is very rare in individuals who take a normal balanced diet. Foods rich in biotin are egg yolk, liver, cereals, vegetables (spinach, mushrooms) and rice. Symptoms associated with vitamin B7 deficiency include thinning hair, scaly skin rashes around eyes, nose and mouth, and brittle nails. The vitamers include biotin and its ionized and salt forms. FYPO_relaxed.owl CHEBI:16015 biolink:NamedThing L-glutamic acid An optically active form of glutamic acid having L-configuration. FYPO_relaxed.owl CHEBI:15971 biolink:NamedThing L-histidine The L-enantiomer of the amino acid histidine. FYPO_relaxed.owl CHEBI:22658 biolink:NamedThing aspartate family amino acid An L-alpha-amino acid which is L-aspartic acid or any of the essential amino acids biosynthesised from it (asparagine, lysine, methionine, threonine and isoleucine). A closed class. FYPO_relaxed.owl CHEBI:24318 biolink:NamedThing glutamine family amino acid An L-alpha-amino acid which is L-glutamic acid or any of the essential amino acids biosynthesised from it (glutamine, proline and arginine). A closed class. FYPO_relaxed.owl CHEBI:73690 biolink:NamedThing erythrose 4-phosphate/phosphoenolpyruvate family amino acid An L-alpha-amino acid which is biosynthesised from erythrose 4-phosphate and phosphoenolpyruvate (i.e. phenylalanine, tyrosine, and tryptophan). A closed class. FYPO_relaxed.owl CHEBI:15986 biolink:NamedThing polynucleotide A nucleobase-containing molecular entity with a polymeric structure comprised of a linear sequence of 13 or more nucleotide residues. FYPO_relaxed.owl CHEBI:33695 biolink:NamedThing information biomacromolecule FYPO_relaxed.owl CHEBI:36080 biolink:NamedThing protein A biological macromolecule minimally consisting of one polypeptide chain synthesized at the ribosome. FYPO_relaxed.owl CHEBI:61120 biolink:NamedThing nucleobase-containing molecular entity Any compound that has a nucleobase as a part. FYPO_relaxed.owl CHEBI:25608 biolink:NamedThing nucleoside phosphate A nucleobase-containing molecular entity that is a nucleoside in which one or more of the sugar hydroxy groups has been converted into a mono- or poly-phosphate. The term includes both nucleotides and non-nucleotide nucleoside phosphates. FYPO_relaxed.owl CHEBI:33838 biolink:NamedThing nucleoside An N-glycosyl compound that has both a nucleobase, normally adenine, guanine, xanthine, thymine, cytosine or uracil, and either a ribose or deoxyribose as functional parents. FYPO_relaxed.owl CHEBI:47784 biolink:NamedThing nucleotide conjugate FYPO_relaxed.owl CHEBI:23981 biolink:NamedThing ethanolamines FYPO_relaxed.owl CHEBI:32877 biolink:NamedThing primary amine A compound formally derived from ammonia by replacing one hydrogen atom by a hydrocarbyl group. FYPO_relaxed.owl CHEBI:17062 biolink:NamedThing primary aliphatic amine FYPO_relaxed.owl CHEBI:50471 biolink:NamedThing primary arylamine A primary amine formally derived from ammonia by replacing one hydrogen atom by an aryl group. R-NH2 where R is an aryl group. FYPO_relaxed.owl CHEBI:17203 biolink:NamedThing L-proline Pyrrolidine in which the pro-S hydrogen at position 2 is substituted by a carboxylic acid group. L-Proline is the only one of the twenty DNA-encoded amino acids which has a secondary amino group alpha to the carboxyl group. It is an essential component of collagen and is important for proper functioning of joints and tendons. It also helps maintain and strengthen heart muscles. FYPO_relaxed.owl CHEBI:18050 biolink:NamedThing L-glutamine An optically active form of glutamine having L-configuration. FYPO_relaxed.owl CHEBI:16016 biolink:NamedThing dihydroxyacetone A ketotriose consisting of acetone bearing hydroxy substituents at positions 1 and 3. The simplest member of the class of ketoses and the parent of the class of glycerones. FYPO_relaxed.owl CHEBI:24982 biolink:NamedThing ketotriose Any ketone-containing triose. FYPO_relaxed.owl CHEBI:16020 biolink:NamedThing 1-methyladenosine A methyladenosine carrying a methyl substituent at position 1. FYPO_relaxed.owl CHEBI:25273 biolink:NamedThing methyladenosine FYPO_relaxed.owl CHEBI:16038 biolink:NamedThing phosphatidylethanolamine A class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxy group of ethanolamine. FYPO_relaxed.owl CHEBI:36314 biolink:NamedThing glycerophosphoethanolamine FYPO_relaxed.owl CHEBI:64574 biolink:NamedThing lysophosphatidylethanolamine A glycerophosphoethanolamine resulting from partial hydrolysis of a phosphatidylethanolamine, which removes one of the fatty acid groups. The structure is depicted in the image where R(1) = acyl, R(2) = H or where R(1) = H, R(2) = acyl. FYPO_relaxed.owl CHEBI:16040 biolink:NamedThing cytosine An aminopyrimidine that is pyrimidin-2-one having the amino group located at position 4. FYPO_relaxed.owl CHEBI:26432 biolink:NamedThing pyrimidine nucleobase A nucleobase whose skeleton is derived from pyrimidine. FYPO_relaxed.owl CHEBI:17568 biolink:NamedThing uracil A common and naturally occurring pyrimidine nucleobase in which the pyrimidine ring is substituted with two oxo groups at positions 2 and 4. Found in RNA, it base pairs with adenine and replaces thymine during DNA transcription. FYPO_relaxed.owl CHEBI:17821 biolink:NamedThing thymine A pyrimidine nucleobase that is uracil in which the hydrogen at position 5 is replaced by a methyl group. FYPO_relaxed.owl CHEBI:38337 biolink:NamedThing pyrimidone A pyrimidine carrying one or more oxo substituents. FYPO_relaxed.owl CHEBI:43254 biolink:NamedThing (4S)-4-hydroxy-3,4-dihydropyrimidin-2(1H)-one FYPO_relaxed.owl CHEBI:38338 biolink:NamedThing aminopyrimidine A member of the class of pyrimidines that is pyrimidine substituted by at least one amino group and its derivatives. FYPO_relaxed.owl CHEBI:26948 biolink:NamedThing vitamin B1 Any member of the group of 1,3-thiazolium cations that exhibit biological activity against vitamin B1 deficiency in animals. Symptoms of vitamin B1 deficiency include constipation, loss of apetite, fatigue, nausea, delirium, blurry vision and muscle weakness. Severe vitamin B1 deficiency can also lead to a disease known as beriberi. Vitamin B1 consists of the vitamer thiamin and its acid, aldehyde and phosphorylated derivatives (and their corresponding ionized, salt and hydrate forms). FYPO_relaxed.owl CHEBI:33429 biolink:NamedThing monoatomic monoanion FYPO_relaxed.owl CHEBI:79389 biolink:NamedThing monovalent inorganic anion Any inorganic anion with a valency of one. FYPO_relaxed.owl CHEBI:16301 biolink:NamedThing nitrite The nitrogen oxoanion formed by loss of a proton from nitrous acid. FYPO_relaxed.owl CHEBI:17632 biolink:NamedThing nitrate A nitrogen oxoanion formed by loss of a proton from nitric acid. Principal species present at pH 7.3. FYPO_relaxed.owl CHEBI:29222 biolink:NamedThing hypochlorite FYPO_relaxed.owl CHEBI:29337 biolink:NamedThing azanide FYPO_relaxed.owl CHEBI:29772 biolink:NamedThing hydroxyazanide An inorganic anion that is the conjugate base of hydroxylamine, arising from deprotonation of the amino function. FYPO_relaxed.owl CHEBI:33522 biolink:NamedThing hydrogentellurite A monovalent inorganic anion obtained by removal of a proton from H2TeO3 FYPO_relaxed.owl CHEBI:35169 biolink:NamedThing dihydrogenvanadate A monovalent inorganic anion that consists of vanadic acid where one of the three OH groups has been deprotonated. FYPO_relaxed.owl CHEBI:39745 biolink:NamedThing dihydrogenphosphate A monovalent inorganic anion that consists of phosphoric acid in which one of the three OH groups has been deprotonated. FYPO_relaxed.owl CHEBI:16072 biolink:NamedThing maleimide A cyclic dicarboximide in which the two carboacyl groups on nitrogen together with the nitogen itself form a 1H-pyrrole-2,5-dione structure. FYPO_relaxed.owl CHEBI:55417 biolink:NamedThing maleimides Compounds containing a cyclic dicarboximide skeleton in which the two carboacyl groups on nitrogen together with the nitrogen itself form a 1H-pyrrole-2,5-dione structure. FYPO_relaxed.owl CHEBI:44485 biolink:NamedThing N-ethylmaleimide A member of the class of maleimides that is the N-ethyl derivative of maleimide. FYPO_relaxed.owl CHEBI:27561 biolink:NamedThing oxirane A saturated organic heteromonocyclic parent that is a three-membered heterocycle of two carbon atoms and one oxygen atom. FYPO_relaxed.owl CHEBI:30363 biolink:NamedThing isobutane An alkane that is propane substituted by a methyl group at position 2. FYPO_relaxed.owl CHEBI:32879 biolink:NamedThing propane FYPO_relaxed.owl CHEBI:37808 biolink:NamedThing butane A straight chain alkane composed of 4 carbon atoms. FYPO_relaxed.owl CHEBI:42266 biolink:NamedThing ethane An alkane comprising of two carbon atoms. FYPO_relaxed.owl CHEBI:35107 biolink:NamedThing azane Saturated acyclic nitrogen hydrides having the general formula NnHn+2. FYPO_relaxed.owl CHEBI:33405 biolink:NamedThing hydracid A hydracid is a compound which contains hydrogen that is not bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). FYPO_relaxed.owl CHEBI:18140 biolink:NamedThing hydrogen halide FYPO_relaxed.owl CHEBI:18407 biolink:NamedThing hydrogen cyanide A one-carbon compound consisting of a methine group triple bonded to a nitrogen atom FYPO_relaxed.owl CHEBI:36856 biolink:NamedThing hydrogen isocyanide FYPO_relaxed.owl CHEBI:33535 biolink:NamedThing sulfur hydride FYPO_relaxed.owl CHEBI:29919 biolink:NamedThing hydrosulfide FYPO_relaxed.owl CHEBI:16150 biolink:NamedThing benzoate The simplest member of the class of benzoates that is the conjugate base of benzoic acid, comprising a benzoic acid core with a proton missing to give a charge of -1. FYPO_relaxed.owl CHEBI:24675 biolink:NamedThing hydroxybenzoate Any benzoate derivative carrying a single carboxylate group and at least one hydroxy substituent. FYPO_relaxed.owl CHEBI:25236 biolink:NamedThing methoxybenzoate FYPO_relaxed.owl CHEBI:87196 biolink:NamedThing 2',4',5',7'-tetrabromo-2,3,4,5-tetrachlorofluorescein(2-) A benzoate anion resulting from the removal of protons from the phenolic hydroxy group and the carboxy group of 2',4',5',7'-tetrabromo-2,3,4,5-tetrachlorofluorescein. FYPO_relaxed.owl CHEBI:16151 biolink:NamedThing 3,4-dihydrocoumarin A chromanone that is the 3,4-dihydro derivative of coumarin. FYPO_relaxed.owl CHEBI:38763 biolink:NamedThing chromanone FYPO_relaxed.owl CHEBI:16152 biolink:NamedThing 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate FYPO_relaxed.owl CHEBI:37328 biolink:NamedThing phosphatidylinositol bisphosphate FYPO_relaxed.owl CHEBI:18348 biolink:NamedThing 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate A phosphatidylinositol bisphosphate in which the two phosphate groups are at C-4 and C-5 of the inositol moiety which has the 1D-myo configuration. FYPO_relaxed.owl CHEBI:16162 biolink:NamedThing o-orsellinate A dihydroxybenzoate that is the conjugate base of o-orsellinic acid. FYPO_relaxed.owl CHEBI:36084 biolink:NamedThing dihydroxybenzoate A hydroxybenzoate that is the conjugate base of dihydroxybenzoic acid. FYPO_relaxed.owl CHEBI:33482 biolink:NamedThing sulfur oxoanion FYPO_relaxed.owl CHEBI:17137 biolink:NamedThing hydrogensulfite FYPO_relaxed.owl CHEBI:33543 biolink:NamedThing sulfonate The sulfur oxoanion formed by deprotonation of sulfonic acid. FYPO_relaxed.owl CHEBI:45696 biolink:NamedThing hydrogensulfate FYPO_relaxed.owl CHEBI:48154 biolink:NamedThing sulfur oxide FYPO_relaxed.owl CHEBI:16196 biolink:NamedThing oleic acid An octadec-9-enoic acid in which the double bond at C-9 has Z (cis) stereochemistry. FYPO_relaxed.owl CHEBI:36021 biolink:NamedThing octadec-9-enoic acid An octadecenoic acid with a double bond at C-9. FYPO_relaxed.owl CHEBI:16199 biolink:NamedThing urea A carbonyl group with two C-bound amine groups. The commercially available fertilizer has an analysis of 46-0-0 (N-P2O5-K2O). FYPO_relaxed.owl CHEBI:16397 biolink:NamedThing formamide The simplest monocarboxylic acid amide, obtained by formal condensation of formic acid with ammonia. The parent of the class of formaldehydes. FYPO_relaxed.owl CHEBI:22645 biolink:NamedThing arenecarboxamide A monocarboxylic acid amide in which the amide linkage is bonded directly to an arene ring system. FYPO_relaxed.owl CHEBI:25461 biolink:NamedThing myxothiazol A 2,4'-bi-1,3-thiazole substituted at the 4-position with a (1E,3S,4R,5E)-7-amino-3,5-dimethoxy-4-methyl-7-oxohepta-1,5-dien-1-yl] group and at the 2'-position with a (2S,3E,5E)-7-methylocta-3,5-dien-2-yl group. It is an inhibitor of coenzyme Q - cytochrome c reductase. FYPO_relaxed.owl CHEBI:26556 biolink:NamedThing 1-ribosylimidazolecarboxamide FYPO_relaxed.owl CHEBI:38940 biolink:NamedThing sunitinib FYPO_relaxed.owl CHEBI:44185 biolink:NamedThing methotrexate FYPO_relaxed.owl CHEBI:65915 biolink:NamedThing FR901464 A spiro-epoxide with potent anticancer activity that lowers the mRNA levels of oncogenes and tumour supressor genes. It is isolated from Pseudomonas sp. no.2663. FYPO_relaxed.owl CHEBI:16830 biolink:NamedThing methylamine The simplest of the methylamines, consisting of ammonia bearing a single methyl substituent. FYPO_relaxed.owl CHEBI:27376 biolink:NamedThing methanesulfonic acid An alkanesulfonic acid in which the alkyl group directly linked to the sulfo functionality is methyl. FYPO_relaxed.owl CHEBI:42820 biolink:NamedThing guanidine An aminocarboxamidine, the parent compound of the guanidines. FYPO_relaxed.owl CHEBI:48376 biolink:NamedThing carbamimidic acid FYPO_relaxed.owl CHEBI:48431 biolink:NamedThing formimidic acid A carboximidic acid that is formic acid in which the carbonyl oxygen is replaced by an imino group. FYPO_relaxed.owl CHEBI:20702 biolink:NamedThing 2-aminopurines Any aminopurine having the amino substituent at the 2-position. FYPO_relaxed.owl CHEBI:16236 biolink:NamedThing ethanol A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group. FYPO_relaxed.owl CHEBI:17578 biolink:NamedThing toluene The simplest member of the class toluenes consisting of a benzene core which bears a single methyl substituent. FYPO_relaxed.owl CHEBI:28262 biolink:NamedThing dimethyl sulfoxide A 2-carbon sulfoxide in which the sulfur atom has two methyl substituents. FYPO_relaxed.owl CHEBI:16240 biolink:NamedThing hydrogen peroxide An inorganic peroxide consisting of two hydroxy groups joined by a covalent oxygen-oxygen single bond. FYPO_relaxed.owl CHEBI:24837 biolink:NamedThing inorganic peroxide Compounds of structure ROOR' in which R and R' are inorganic groups. FYPO_relaxed.owl CHEBI:26523 biolink:NamedThing reactive oxygen species Molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers. FYPO_relaxed.owl CHEBI:24757 biolink:NamedThing hypochlorous acid A chlorine oxoacid with formula HOCl; a weak, unstable acid, it is the active form of chlorine in water. FYPO_relaxed.owl CHEBI:61073 biolink:NamedThing oxygen radical An inorganic radical in which a free electron resides on one or more oxygen atoms of an oxygen species. FYPO_relaxed.owl CHEBI:16247 biolink:NamedThing phospholipid A lipid containing phosphoric acid as a mono- or di-ester. The term encompasses phosphatidic acids and phosphoglycerides. FYPO_relaxed.owl CHEBI:24913 biolink:NamedThing isoprenoid Any lipid formally derived from isoprene (2-methylbuta-1,3-diene), the skeleton of which can generally be discerned in repeated occurrence in the molecule. The skeleton of isoprenoids may differ from strict additivity of isoprene units by loss or shift of a fragment, commonly a methyl group. The class includes both hydrocarbons and oxygenated derivatives. FYPO_relaxed.owl CHEBI:35740 biolink:NamedThing liposaccharide FYPO_relaxed.owl CHEBI:35741 biolink:NamedThing glycerolipid Any member of the group of lipids containing a common glycerol backbone to which at least one fatty acid-derived group is attached. FYPO_relaxed.owl CHEBI:61697 biolink:NamedThing fatty acid derivative Any organic molecular entity derived from a fatty acid. FYPO_relaxed.owl CHEBI:25703 biolink:NamedThing organic phosphate FYPO_relaxed.owl CHEBI:23450 biolink:NamedThing cyclitol phosphate FYPO_relaxed.owl CHEBI:26816 biolink:NamedThing carbohydrate phosphate FYPO_relaxed.owl CHEBI:36711 biolink:NamedThing phosphoethanolamine FYPO_relaxed.owl CHEBI:36952 biolink:NamedThing carboxyalkyl phosphate FYPO_relaxed.owl CHEBI:7794 biolink:NamedThing phosphate monoester An organic phosphate that is phosphoric acid in which one of the hydrogens is replaced by an organyl group. FYPO_relaxed.owl CHEBI:37734 biolink:NamedThing phosphoric ester FYPO_relaxed.owl CHEBI:46961 biolink:NamedThing phytosphingosine FYPO_relaxed.owl CHEBI:16284 biolink:NamedThing dATP A purine 2'-deoxyribonucleoside 5'-triphosphate having adenine as the nucleobase. FYPO_relaxed.owl CHEBI:19237 biolink:NamedThing 2'-deoxyadenosine 5'-phosphate FYPO_relaxed.owl CHEBI:37042 biolink:NamedThing purine 2'-deoxyribonucleoside 5'-triphosphate FYPO_relaxed.owl CHEBI:16497 biolink:NamedThing dGTP A purine 2'-deoxyribonucleoside 5'-triphosphate having guanine as the nucleobase. FYPO_relaxed.owl CHEBI:16828 biolink:NamedThing L-tryptophan The L-enantiomer of tryptophan. FYPO_relaxed.owl CHEBI:33458 biolink:NamedThing nitrogen oxoanion FYPO_relaxed.owl CHEBI:29773 biolink:NamedThing aminooxidanide FYPO_relaxed.owl CHEBI:62764 biolink:NamedThing reactive nitrogen species A family of nitrogen molecular entities which are highly reactive and derived from nitric oxide (.NO) and superoxide (O2.(-)) produced via the enzymatic activity of inducible nitric oxide synthase 2 (NOS2) and NADPH oxidase respectively. FYPO_relaxed.owl CHEBI:16480 biolink:NamedThing nitric oxide A nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom. FYPO_relaxed.owl CHEBI:16311 biolink:NamedThing dCTP A 2'-deoxycytidine phosphate having cytosine as the nucleobase. FYPO_relaxed.owl CHEBI:37043 biolink:NamedThing pyrimidine 2'-deoxyribonucleoside 5'-triphosphate FYPO_relaxed.owl CHEBI:18077 biolink:NamedThing dTTP A thymidine phosphate having a triphosphate group at the 5'-position. FYPO_relaxed.owl CHEBI:37092 biolink:NamedThing 2'-deoxycytidine phosphate FYPO_relaxed.owl CHEBI:16335 biolink:NamedThing adenosine A ribonucleoside composed of a molecule of adenine attached to a ribofuranose moiety via a beta-N(9)-glycosidic bond. FYPO_relaxed.owl CHEBI:17596 biolink:NamedThing inosine A purine nucleoside in which hypoxanthine is attached to ribofuranose via a beta-N(9)-glycosidic bond. FYPO_relaxed.owl CHEBI:24909 biolink:NamedThing hydrocarbyladenosine FYPO_relaxed.owl CHEBI:29014 biolink:NamedThing cordycepin FYPO_relaxed.owl CHEBI:16337 biolink:NamedThing phosphatidic acid A derivative of glycerol in which one hydroxy group, commonly but not necessarily primary, is esterified with phosphoric acid and the other two are esterified with fatty acids. FYPO_relaxed.owl CHEBI:37739 biolink:NamedThing glycerophospholipid Any glycerolipid having a phosphate group ester-linked to a terminal carbon of the glycerol backbone. FYPO_relaxed.owl CHEBI:166988 biolink:NamedThing glycerophosphoglycerophosphoglycerol A glycerophospholipid composed of two molecules of glycerol phosphate covalently linked to a molecule of glycerol, and in which each of the glycerol phosphate moieties may be esterified to one or two fatty acids. FYPO_relaxed.owl CHEBI:24360 biolink:NamedThing glycerophosphoglycerols FYPO_relaxed.owl CHEBI:35766 biolink:NamedThing glycerophosphoserine FYPO_relaxed.owl CHEBI:36313 biolink:NamedThing glycerophosphocholine The glycerol phosphate ester of a phosphocholine. A nutrient with many different roles in human health. FYPO_relaxed.owl CHEBI:36315 biolink:NamedThing glycerophosphoinositol Any glycerophospholipid having the polar alcohol inositol esterified to the phosphate group at the sn-3 position of the glycerol backbone. FYPO_relaxed.owl CHEBI:16349 biolink:NamedThing L-citrulline The L-enantiomer of citrulline. FYPO_relaxed.owl CHEBI:18211 biolink:NamedThing citrulline The parent compound of the citrulline class consisting of ornithine having a carbamoyl group at the N(5)-position. FYPO_relaxed.owl CHEBI:49007 biolink:NamedThing D-citrulline FYPO_relaxed.owl CHEBI:16350 biolink:NamedThing 2'-deoxyribonucleoside 5'-diphosphate FYPO_relaxed.owl CHEBI:37016 biolink:NamedThing 2'-deoxyribonucleoside 5'-phosphate FYPO_relaxed.owl CHEBI:16381 biolink:NamedThing 2'-deoxyribonucleoside 5'-triphosphate FYPO_relaxed.owl CHEBI:16383 biolink:NamedThing cis-aconitate(3-) An aconitate(3-) that is the conjugate base of cis-aconitic acid. FYPO_relaxed.owl CHEBI:22210 biolink:NamedThing aconitate(3-) A tricarboxylic acid trianion that is the conjugate base of aconitic acid. FYPO_relaxed.owl CHEBI:26822 biolink:NamedThing sulfide Any sulfur molecular entity that involves either covalently bonded or anionic sulfur. FYPO_relaxed.owl CHEBI:16389 biolink:NamedThing ubiquinones Any benzoquinone derived from 2,3-dimethoxy-5-methylbenzoquinone; one of a group of naturally occurring homologues. The redox-active quinoid moiety usually carries a polyprenoid side chain at position 6, the number of isoprenoid units in which is species-specific. Ubiquinones are involved in the control of mitochondrial electron transport, and are also potent anti-oxidants. FYPO_relaxed.owl CHEBI:35795 biolink:NamedThing polyprenylbenzoquinone Any member of the class of 1,4-benzoquinones substituted by a polyprenyl-derived side-chain. FYPO_relaxed.owl CHEBI:46691 biolink:NamedThing 2,3-dihydroxy-5-methyl-1,4-benzoquinone FYPO_relaxed.owl CHEBI:67273 biolink:NamedThing monohydroxy-1,4-benzoquinones Any 1,4-benzoquinone carrying a single hydroxy substituent. FYPO_relaxed.owl CHEBI:16857 biolink:NamedThing L-threonine An optically active form of threonine having L-configuration. FYPO_relaxed.owl CHEBI:38182 biolink:NamedThing monohydroxypyridine A hydroxypyridine carrying a single hydroxy substituent. FYPO_relaxed.owl CHEBI:18335 biolink:NamedThing pyridoxamine 5'-phosphate A vitamin B6 phosphate that is the phosphoric ester derivative of pyridoxamine. FYPO_relaxed.owl CHEBI:38196 biolink:NamedThing hydroxymethylpyridine Any member of the class of pyridines carrying a hydroxymethyl substituent at unspecified position. FYPO_relaxed.owl CHEBI:38198 biolink:NamedThing aminoalkylpyridine FYPO_relaxed.owl CHEBI:16460 biolink:NamedThing polyprenol phosphate A prenol phosphate resulting from the formal condensation of the terminal allylic hydroxy group of a polyprenol with 1 mol eq. of phosphoric acid. FYPO_relaxed.owl CHEBI:26250 biolink:NamedThing prenol phosphate FYPO_relaxed.owl CHEBI:26875 biolink:NamedThing terpenyl phosphate FYPO_relaxed.owl CHEBI:35196 biolink:NamedThing nitrogen oxide FYPO_relaxed.owl CHEBI:36871 biolink:NamedThing inorganic radical FYPO_relaxed.owl CHEBI:36878 biolink:NamedThing inorganic radical ion FYPO_relaxed.owl CHEBI:16482 biolink:NamedThing naphthalene An aromatic hydrocarbon comprising two fused benzene rings. It occurs in the essential oils of numerous plant species e.g. magnolia. FYPO_relaxed.owl CHEBI:36336 biolink:NamedThing naphthalenesulfonic acid FYPO_relaxed.owl CHEBI:9448 biolink:NamedThing terbinafine A tertiary amine that is N-methyl-1-naphthalenemethylamine in which the amino hydrogen is replaced by a 3-(tertbutylethynyl)allyl group. An antifungal agent administered orally (generally as the hydrochloride salt) for the treatment of skin and nail infections. FYPO_relaxed.owl CHEBI:35426 biolink:NamedThing ortho-fused bicyclic arene FYPO_relaxed.owl CHEBI:23625 biolink:NamedThing deoxyguanosine phosphate FYPO_relaxed.owl CHEBI:63573 biolink:NamedThing guanyl deoxyribonucleotide A purine 2'-deoxyribonucleotide where the purine is guanine. FYPO_relaxed.owl CHEBI:16516 biolink:NamedThing 2'-deoxyribonucleoside triphosphate FYPO_relaxed.owl CHEBI:17326 biolink:NamedThing nucleoside 5'-triphoshate FYPO_relaxed.owl CHEBI:26393 biolink:NamedThing purine nucleoside triphosphate FYPO_relaxed.owl CHEBI:26439 biolink:NamedThing pyrimidine nucleoside triphosphate FYPO_relaxed.owl CHEBI:16521 biolink:NamedThing lanosterol A tetracyclic triterpenoid that is lanosta-8,24-diene substituted by a beta-hydroxy group at the 3beta position. It is the compound from which all steroids are derived. FYPO_relaxed.owl CHEBI:26893 biolink:NamedThing tetracyclic triterpenoid Any triterpenoid consisting of a tetracyclic skeleton. FYPO_relaxed.owl CHEBI:35348 biolink:NamedThing 3beta-sterol A sterol in which the hydroxy group at position 3 has beta- configuration. FYPO_relaxed.owl CHEBI:16933 biolink:NamedThing ergosterol A phytosterol consisting of ergostane having double bonds at the 5,6-, 7,8- and 22,23-positions as well as a 3beta-hydroxy group. FYPO_relaxed.owl CHEBI:18249 biolink:NamedThing ergosta-5,7,22,24(28)-tetraen-3beta-ol A 3beta-sterol having double bonds in the 5-, 7- and 22-positions and a methylene group at position 24. FYPO_relaxed.owl CHEBI:16541 biolink:NamedThing protein polypeptide chain A naturally occurring polypeptide synthesized at the ribosome. FYPO_relaxed.owl CHEBI:64121 biolink:NamedThing P-factor A polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu. A peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus. FYPO_relaxed.owl CHEBI:16551 biolink:NamedThing alpha,alpha-trehalose A trehalose in which both glucose residues have alpha-configuration at the anomeric carbon. FYPO_relaxed.owl CHEBI:27082 biolink:NamedThing trehalose A disaccharide formed by a (1<->1)-glycosidic bond between two units of D-glucose. FYPO_relaxed.owl CHEBI:16566 biolink:NamedThing sphinganine A 2-aminooctadecane-1,3-diol having (2S,3R)-configuration. FYPO_relaxed.owl CHEBI:46968 biolink:NamedThing 2-aminooctadecane-1,3-diol An aminodiol that is octadecane bearing two hydroxy substituents at positions 1 and 3 as well as an amino substituent at position 2. FYPO_relaxed.owl CHEBI:16605 biolink:NamedThing allyl alcohol A propenol in which the C=C bond connects C-2 and C-3. It is has been found in garlic (Allium sativum). Formerly used as a herbicide for the control of various grass and weed seeds. FYPO_relaxed.owl CHEBI:16610 biolink:NamedThing spermidine A triamine that is the 1,5,10-triaza derivative of decane. FYPO_relaxed.owl CHEBI:38751 biolink:NamedThing triamine Any polyamine that contained three amino groups. FYPO_relaxed.owl CHEBI:39474 biolink:NamedThing polyazaalkane Any azaalkane in which two or more carbons in the chain are replaced by nitrogen. FYPO_relaxed.owl CHEBI:46687 biolink:NamedThing diazaalkane FYPO_relaxed.owl CHEBI:16618 biolink:NamedThing 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate FYPO_relaxed.owl CHEBI:60169 biolink:NamedThing phosphatidylinositol trisphosphate A derivative of phosphatidylinositol in which the inositol ring is phosphorylated at three unspecified positions. FYPO_relaxed.owl CHEBI:16632 biolink:NamedThing vanillate A methoxybenzoate that is the conjugate base of vanillic acid. FYPO_relaxed.owl CHEBI:25388 biolink:NamedThing monohydroxybenzoate A hydroxybenzoate carrying a single hydroxy substituent at unspecified position. FYPO_relaxed.owl CHEBI:16634 biolink:NamedThing raffinose A trisaccharide composed of alpha-D-galactopyranose, alpha-D-glucopyranose and beta-D-fructofuranose joined in sequence by 1->6 and 1<->2 glycosidic linkages, respectively. FYPO_relaxed.owl CHEBI:27150 biolink:NamedThing trisaccharide FYPO_relaxed.owl CHEBI:74961 biolink:NamedThing raffinose family oligosaccharide Any oligosaccharide that has a biosynthetic pathway in common with that of raffinose. FYPO_relaxed.owl CHEBI:16643 biolink:NamedThing L-methionine The L-enantiomer of methionine. FYPO_relaxed.owl CHEBI:17053 biolink:NamedThing L-aspartic acid The L-enantiomer of aspartic acid. FYPO_relaxed.owl CHEBI:17191 biolink:NamedThing L-isoleucine The L-enantiomer of isoleucine. FYPO_relaxed.owl CHEBI:17196 biolink:NamedThing L-asparagine An optically active form of asparagine having L-configuration. FYPO_relaxed.owl CHEBI:18019 biolink:NamedThing L-lysine An L-alpha-amino acid; the L-isomer of lysine. FYPO_relaxed.owl CHEBI:16646 biolink:NamedThing carbohydrate Any member of the class of organooxygen compounds that is a polyhydroxy-aldehyde or -ketone or a lactol resulting from their intramolecular condensation (monosaccharides); substances derived from these by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom; and polymeric products arising by intermolecular acetal formation between two or more such molecules (disaccharides, polysaccharides and oligosaccharides). Carbohydrates contain only carbon, hydrogen and oxygen atoms; prior to any oxidation or reduction, most have the empirical formula Cm(H2O)n. Compounds obtained from carbohydrates by substitution, etc., are known as carbohydrate derivatives and may contain other elements. Cyclitols are generally not regarded as carbohydrates. FYPO_relaxed.owl CHEBI:78616 biolink:NamedThing carbohydrates and carbohydrate derivatives Any organooxygen compound that is a polyhydroxy-aldehyde or -ketone, or a compound derived from one. Carbohydrates contain only carbon, hydrogen and oxygen and usually have an empirical formula Cm(H2O)n; carbohydrate derivatives may contain other elements by substitution or condensation. FYPO_relaxed.owl CHEBI:167559 biolink:NamedThing glycan Any oligosaccharide, polysaccharide or their derivatives consisting of monosaccharides or monosaccharide derivatives linked by glycosidic bonds. See also http://www.ontobee.org/ontology/GNO?iri=http://purl.obolibrary.org/obo/GNO_00000001. FYPO_relaxed.owl CHEBI:63299 biolink:NamedThing carbohydrate derivative Any organooxygen compound derived from a carbohydrate by replacement of one or more hydroxy group(s) by an amino group, a thiol group or similar heteroatomic groups. The term also includes derivatives of these compounds. FYPO_relaxed.owl CHEBI:31577 biolink:NamedThing ethylenediamine derivative Any organic amino compound that is a derivative of ethylenediamine. FYPO_relaxed.owl CHEBI:32952 biolink:NamedThing amine A compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. FYPO_relaxed.owl CHEBI:33709 biolink:NamedThing amino acid A carboxylic acid containing one or more amino groups. FYPO_relaxed.owl CHEBI:33860 biolink:NamedThing aromatic amine An amino compound in which the amino group is linked directly to an aromatic system. FYPO_relaxed.owl CHEBI:46686 biolink:NamedThing azaalkane FYPO_relaxed.owl CHEBI:50994 biolink:NamedThing primary amino compound A compound formally derived from ammonia by replacing one hydrogen atom by an organyl group. FYPO_relaxed.owl CHEBI:50995 biolink:NamedThing secondary amino compound A compound formally derived from ammonia by replacing two hydrogen atoms by organyl groups. FYPO_relaxed.owl CHEBI:60971 biolink:NamedThing aminophospholipid A phospholipid that contains one or more amino groups. FYPO_relaxed.owl CHEBI:88061 biolink:NamedThing polyamine Any organic amino compound that contains two or more amino groups. FYPO_relaxed.owl PR:000018263 biolink:NamedThing amino acid chain An organic amino compound that consists of amino acid residues (unmodified amino-acid residues and/or modified amino-acid residues) linked by peptide bonds or derivatives of such bonds. FYPO_relaxed.owl CHEBI:24610 biolink:NamedThing homocysteines FYPO_relaxed.owl CHEBI:166831 biolink:NamedThing copper chelator A chelator that is any compound containing a ligand (typically organic) which is able to form a bond to a central copper atom at two or more points. FYPO_relaxed.owl CHEBI:38161 biolink:NamedThing chelator A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate. FYPO_relaxed.owl CHEBI:38157 biolink:NamedThing iron chelator FYPO_relaxed.owl CHEBI:27232 biolink:NamedThing uridine 5'-phosphate FYPO_relaxed.owl CHEBI:17659 biolink:NamedThing UDP FYPO_relaxed.owl CHEBI:16701 biolink:NamedThing nucleoside 5'-phosphate A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-5 of the ribose ring is mono-, di-, tri- or tetra-phosphorylated. FYPO_relaxed.owl CHEBI:29075 biolink:NamedThing mononucleotide FYPO_relaxed.owl CHEBI:20706 biolink:NamedThing 6-aminopurines Any compound having 6-aminopurine (adenine) as part of its structure. FYPO_relaxed.owl CHEBI:25340 biolink:NamedThing methylpyridines Any member of the class of pyridines that carries at least one methyl substituent. FYPO_relaxed.owl CHEBI:33842 biolink:NamedThing aromatic annulene FYPO_relaxed.owl CHEBI:167164 biolink:NamedThing mineral nutrient A mineral that is an inorganic nutrient which must be ingested and absorbed in adequate amounts to satisfy a wide range of essential metabolic and/or structural functions in the human body. FYPO_relaxed.owl CHEBI:46662 biolink:NamedThing mineral In general, a mineral is a chemical substance that is normally crystalline formed and has been formed as a result of geological processes. The term also includes metamict substances (naturally occurring, formerly crystalline substances whose crystallinity has been destroyed by ionising radiation) and can include naturally occurring amorphous substances that have never been crystalline ('mineraloids') such as georgite and calciouranoite as well as substances formed by the action of geological processes on bigenic compounds ('biogenic minerals'). FYPO_relaxed.owl CHEBI:167183 biolink:NamedThing piscicide A substance which is poisonous to fish and is primarily used to eliminate dominant species of fish in water. FYPO_relaxed.owl CHEBI:22153 biolink:NamedThing acaricide A substance used to destroy pests of the subclass Acari (mites and ticks). FYPO_relaxed.owl CHEBI:24127 biolink:NamedThing fungicide A substance used to destroy fungal pests. FYPO_relaxed.owl CHEBI:24527 biolink:NamedThing herbicide A substance used to destroy plant pests. FYPO_relaxed.owl CHEBI:24852 biolink:NamedThing insecticide Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects. FYPO_relaxed.owl CHEBI:25491 biolink:NamedThing nematicide A substance used to destroy pests of the phylum Nematoda (roundworms). FYPO_relaxed.owl CHEBI:33288 biolink:NamedThing rodenticide A substance used to destroy rodent pests. FYPO_relaxed.owl CHEBI:16728 biolink:NamedThing 2-acyl-sn-glycero-3-phosphocholine(1+) A 2-acylglycerophosphocholine in which the glycerol moiety has sn stereochemistry and which has an unspecified acyl group attached at the 2-position. FYPO_relaxed.owl CHEBI:23324 biolink:NamedThing citrullines FYPO_relaxed.owl CHEBI:59755 biolink:NamedThing alpha-amino fatty acid A fatty acid with an amino substituent at position C-2. FYPO_relaxed.owl CHEBI:84060 biolink:NamedThing 4-fluorophenylalanine A phenylalanine derivative in which the hydrogen at position 4 on the benzene ring is replaced by a fluoro group. FYPO_relaxed.owl CHEBI:16749 biolink:NamedThing 1-phosphatidyl-1D-myo-inositol A phosphatidylinositol in which the inositol moiety is the 1D-myo isomer and the phosphatidyl group is located at its position 1. FYPO_relaxed.owl CHEBI:28874 biolink:NamedThing phosphatidylinositol Any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol. FYPO_relaxed.owl CHEBI:18179 biolink:NamedThing phosphoinositide Any phosphatidylinositol that is phosphorylated at one or more of the hydroxy groups of inositol. FYPO_relaxed.owl CHEBI:16761 biolink:NamedThing ADP A purine ribonucleoside 5'-diphosphate having adenine as the nucleobase. FYPO_relaxed.owl CHEBI:37038 biolink:NamedThing purine ribonucleoside 5'-diphosphate FYPO_relaxed.owl CHEBI:37096 biolink:NamedThing adenosine 5'-phosphate FYPO_relaxed.owl CHEBI:16802 biolink:NamedThing sedoheptulose FYPO_relaxed.owl CHEBI:33949 biolink:NamedThing ketoheptose A heptose with a (potential) ketone group at the 2-position. FYPO_relaxed.owl CHEBI:16810 biolink:NamedThing 2-oxoglutarate(2-) An oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid. FYPO_relaxed.owl CHEBI:17295 biolink:NamedThing L-phenylalanine The L-enantiomer of phenylalanine. FYPO_relaxed.owl CHEBI:17895 biolink:NamedThing L-tyrosine An optically active form of tyrosine having L-configuration. FYPO_relaxed.owl CHEBI:43799 biolink:NamedThing butan-1-amine A primary aliphatic amine that is butane substituted by an amino group at position 1. FYPO_relaxed.owl CHEBI:25274 biolink:NamedThing methylamines FYPO_relaxed.owl CHEBI:35692 biolink:NamedThing dicarboxylic acid Any carboxylic acid containing two carboxy groups. FYPO_relaxed.owl CHEBI:189840 biolink:NamedThing dicarboxylic fatty acid Any fatty acid containing two carboxy groups. FYPO_relaxed.owl CHEBI:36145 biolink:NamedThing oxo dicarboxylic acid Any dicarboxylic acid carrying one or more oxo groups. FYPO_relaxed.owl CHEBI:61355 biolink:NamedThing 3-hydroxy carboxylic acid Any hydroxy carboxylic acid which contains a hydroxy group located beta- to the carboxylic acid group. FYPO_relaxed.owl CHEBI:63655 biolink:NamedThing (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid A 3-hydroxy carboxylic acid that is (3R,5R)-3,5-dihydroxyheptanoic acid in which one of the methyl hydrogens is substituted by a (1S,2S,6S,8S,8aR)-6,8-dihydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl group. FYPO_relaxed.owl CHEBI:16838 biolink:NamedThing polyphosphate The phosphorus oxoanion formed from polyphosphoric acid by proton loss from each of the phosphate units. The major species at pH 7.3. FYPO_relaxed.owl CHEBI:33461 biolink:NamedThing phosphorus oxoanion FYPO_relaxed.owl CHEBI:35780 biolink:NamedThing phosphate ion A phosphorus oxoanion that is the conjugate base of phosphoric acid. FYPO_relaxed.owl CHEBI:38831 biolink:NamedThing 2-benzofurans FYPO_relaxed.owl CHEBI:72596 biolink:NamedThing papulacandin Any of the carbohydrate-containing antibiotic compounds obtained from the deuteromycetous fungus Papularia sphaerosperma and generally consisting of o-orsellinic acid linked via a spirocyclic structure to a lactose moiety with two different side-chains: a shorter fatty-acid chain at the O-(6') position and a longer side-chain at the O-(3) position of the glucose moiety. Papulacandin D, the simplest member of the papulacandin family, lacks the O-(6'-acyl-beta-galactoside) at the O-(4) position of the glucose residue. The papulacandins show potent antifungal activity against Candida albicans, Geotrichum lactis, Saccharomyces cerevisiae, and Pneumocytis carinii, but are inactive against filamentous fungi, bacteria, and protazoa. FYPO_relaxed.owl CHEBI:16856 biolink:NamedThing glutathione A tripeptide compound consisting of glutamic acid attached via its side chain to the N-terminus of cysteinylglycine. FYPO_relaxed.owl CHEBI:23853 biolink:NamedThing dithiol FYPO_relaxed.owl CHEBI:25189 biolink:NamedThing 1,4-dimercaptobutane-2,3-diol A glycol that is butane-2,3-diol in which a hydrogen from each of the methyl groups is replaced by a thiol group. FYPO_relaxed.owl CHEBI:47908 biolink:NamedThing alkanethiol An alkanethiol is a compound in which a sulfanyl group, -SH, is attached to an alkyl group. FYPO_relaxed.owl CHEBI:47923 biolink:NamedThing tripeptide Any oligopeptide that consists of three amino-acid residues connected by peptide linkages. FYPO_relaxed.owl CHEBI:83824 biolink:NamedThing L-cysteine derivative A proteinogenic amino acid derivative resulting from the formal reaction of L-cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of L-cysteine by a heteroatom. FYPO_relaxed.owl CHEBI:79057 biolink:NamedThing hercynylcysteine sulfoxide A L-histidine derivative which is an intermediate in the synthesis of ergothioneine, a compound found in certain fungi and mycobacteria. FYPO_relaxed.owl CHEBI:16862 biolink:NamedThing nucleoside 5'-diphosphate FYPO_relaxed.owl CHEBI:17188 biolink:NamedThing nucleoside 5'-monophosphate FYPO_relaxed.owl CHEBI:23523 biolink:NamedThing cytidine phosphate FYPO_relaxed.owl CHEBI:23621 biolink:NamedThing deoxycytidine phosphate FYPO_relaxed.owl CHEBI:27001 biolink:NamedThing thymidine phosphate FYPO_relaxed.owl CHEBI:27237 biolink:NamedThing uridine phosphate FYPO_relaxed.owl CHEBI:36976 biolink:NamedThing nucleotide A nucleotide is a nucleoside phosphate resulting from the condensation of the 3 or 5 hydroxy group of a nucleoside with phosphoric acid. FYPO_relaxed.owl CHEBI:37123 biolink:NamedThing nucleoside bisphosphate FYPO_relaxed.owl CHEBI:16893 biolink:NamedThing sphinganine 1-phosphate A sphingoid 1-phosphate that is the monophosphorylated derivative of sphinganine. FYPO_relaxed.owl CHEBI:77068 biolink:NamedThing sphingoid 1-phosphate A generic class of phosphosphingolipids, encompassing monophosphorylated derivatives of sphinganine, its homologues and stereoisomers, as well as the hydroxy and unsaturated derivatives of these compounds. FYPO_relaxed.owl CHEBI:16907 biolink:NamedThing 4-nitroquinoline N-oxide A quinoline N-oxide carrying a nitro substituent at position 4. FYPO_relaxed.owl CHEBI:26508 biolink:NamedThing quinoline N-oxide FYPO_relaxed.owl CHEBI:16916 biolink:NamedThing oligosaccharide phosphate An oligosaccharide derivative in which at least one hydroxy group has been phosphorylated. FYPO_relaxed.owl CHEBI:22300 biolink:NamedThing aldonic acid phosphate An aldonic acid in which at least one of the hydroxy groups has been phosphorylated. FYPO_relaxed.owl CHEBI:23843 biolink:NamedThing disaccharide phosphate FYPO_relaxed.owl CHEBI:26187 biolink:NamedThing polyprenyl phospho carbohydrate FYPO_relaxed.owl CHEBI:33447 biolink:NamedThing phospho sugar Any monosaccharide containing an alcoholic hydroxy group esterified with phosphoric acid. FYPO_relaxed.owl CHEBI:63563 biolink:NamedThing oligosaccharide derivative A carbohydrate derivative that is formally obtained from an oligosaccharide. FYPO_relaxed.owl CHEBI:22483 biolink:NamedThing amino oligosaccharide FYPO_relaxed.owl CHEBI:71274 biolink:NamedThing mannooligosaccharide derivative An oligosaccharide derivative that is derived from a mannooligosaccharide. FYPO_relaxed.owl CHEBI:1722 biolink:NamedThing 3beta-hydroxy-Delta(5)-steroid Any 3beta-hydroxy-steroid that contains a double bond between positions 5 and 6. FYPO_relaxed.owl CHEBI:26125 biolink:NamedThing phytosterols Sterols similar to cholesterol which occur in plants and vary only in carbon side chains and/or presence or absence of a double bond. FYPO_relaxed.owl CHEBI:16948 biolink:NamedThing N-acetyl-D-glucosaminic acid The N-acetyl derivative of D-glucosaminic acid. FYPO_relaxed.owl CHEBI:33772 biolink:NamedThing gluconic acid derivative A hexonic acid derivative that is formally obtained from gluconic acid. FYPO_relaxed.owl CHEBI:16958 biolink:NamedThing beta-alanine A naturally-occurring beta-amino acid comprising propionic acid with the amino group in the 3-position. FYPO_relaxed.owl CHEBI:33706 biolink:NamedThing beta-amino acid A non-proteinogenic amino acid in which the amino group is located on the carbon atom at the position beta to the carboxy group. FYPO_relaxed.owl CHEBI:16966 biolink:NamedThing heteroglycan A polysaccharide composed of two or more different types of monosaccharides, FYPO_relaxed.owl CHEBI:18154 biolink:NamedThing polysaccharide A biomacromolecule consisting of large numbers of monosaccharide residues linked glycosidically. This term is commonly used only for those containing more than ten monosaccharide residues. FYPO_relaxed.owl CHEBI:37164 biolink:NamedThing homopolysaccharide Glycans composed of a single type of monosaccharide residue. They are named by replacing the ending '-ose' of the sugar by '-an'. FYPO_relaxed.owl CHEBI:59520 biolink:NamedThing N-glycan The term used to refer to the carbohydrate portion of N-glycoproteins when attached to a nitrogen from asparagine or arginine side-chains. FYPO_relaxed.owl CHEBI:16976 biolink:NamedThing hygromycin B FYPO_relaxed.owl CHEBI:24753 biolink:NamedThing hygromycin FYPO_relaxed.owl CHEBI:71989 biolink:NamedThing ortho ester Any organooxygen compound that has the general formula RC(OR(1))(OR(2))(OR(3)), where R(1), R(2), R(3) =/= H. FYPO_relaxed.owl CHEBI:16988 biolink:NamedThing D-ribose A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in D-glyceraldehyde. FYPO_relaxed.owl CHEBI:33942 biolink:NamedThing ribose Any aldopentose where the open-chain form has all the hydroxy groups on the same side in the Fischer projection. Occurrs in two enantiomeric forms, D- and L-ribose, of which only the former is found in nature. FYPO_relaxed.owl CHEBI:46997 biolink:NamedThing L-ribose A ribose in which the chiral carbon atom furthest away from the aldehyde group (C4') has the same configuration as in L-glyceraldehyde. FYPO_relaxed.owl CHEBI:46998 biolink:NamedThing ribofuranose A cyclic ribose having a 5-membered tetrahydrofuran ring; the predominant (C3'-endo) form of the two cyclic structures (the other is the "C2'-endo" form, having a 6-membered ring) adopted by ribose in aqueous solution. FYPO_relaxed.owl CHEBI:16991 biolink:NamedThing deoxyribonucleic acid High molecular weight, linear polymers, composed of nucleotides containing deoxyribose and linked by phosphodiester bonds; DNA contain the genetic information of organisms. FYPO_relaxed.owl CHEBI:33696 biolink:NamedThing nucleic acid A macromolecule made up of nucleotide units and hydrolysable into certain pyrimidine or purine bases (usually adenine, cytosine, guanine, thymine, uracil), D-ribose or 2-deoxy-D-ribose and phosphoric acid. FYPO_relaxed.owl CHEBI:33697 biolink:NamedThing ribonucleic acid High molecular weight, linear polymers, composed of nucleotides containing ribose and linked by phosphodiester bonds; RNA is central to the synthesis of proteins. FYPO_relaxed.owl CHEBI:17016 biolink:NamedThing L-methionine S-oxide FYPO_relaxed.owl CHEBI:49033 biolink:NamedThing methionine S-oxide The S-oxide derivative of methionine. It is a biomarker of oxidative stress. FYPO_relaxed.owl CHEBI:49034 biolink:NamedThing D-methionine S-oxide FYPO_relaxed.owl CHEBI:36895 biolink:NamedThing monoatomic fluorine FYPO_relaxed.owl CHEBI:17111 biolink:NamedThing 5-O-phosphono-alpha-D-ribofuranosyl diphosphate A derivative of alpha-D-ribose having a phosphate group at the 5-position and a diphosphate at the 1-position. FYPO_relaxed.owl CHEBI:48956 biolink:NamedThing 5-O-phosphono-D-ribofuranosyl diphosphate FYPO_relaxed.owl CHEBI:58954 biolink:NamedThing straight-chain saturated fatty acid anion Any saturated fatty acid anion lacking a carbon side-chain. FYPO_relaxed.owl CHEBI:25629 biolink:NamedThing octadecanoate A fatty acid anion 18:0 that is the conjugate base of octadecanoic acid (stearic acid). Stearates have a variety of uses in the pharmaceutical industry. FYPO_relaxed.owl CHEBI:25646 biolink:NamedThing octanoate A straight-chain saturated fatty acid anion that is the conjugate base of octanoic acid (caprylic acid); believed to block adipogenesis. FYPO_relaxed.owl CHEBI:31014 biolink:NamedThing tetracosanoate A straight-chain saturated fatty acid anion that is the conjugate base of tetracosanoic acid (lignoceric acid), formed by deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:78116 biolink:NamedThing fatty acid anion 6:0 Any saturated fatty acid anion containing 6 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. FYPO_relaxed.owl CHEBI:17158 biolink:NamedThing methylglyoxal A 2-oxo aldehyde derived from propanal. FYPO_relaxed.owl CHEBI:27659 biolink:NamedThing 2-oxo aldehyde Any aldehyde having an oxo substituent at the 2-position. FYPO_relaxed.owl CHEBI:171664 biolink:NamedThing antiamoebic agent An antiparasitic agent which is effective against amoeba, a genus of single-celled amoeboids in the family Amoebidae. FYPO_relaxed.owl CHEBI:35442 biolink:NamedThing antiparasitic agent A substance used to treat or prevent parasitic infections. FYPO_relaxed.owl CHEBI:35443 biolink:NamedThing anthelminthic drug Substance intended to kill parasitic worms (helminths). FYPO_relaxed.owl CHEBI:35820 biolink:NamedThing antiprotozoal drug Any antimicrobial drug which is used to treat or prevent protozoal infections. FYPO_relaxed.owl CHEBI:24898 biolink:NamedThing isoleucine A 2-amino-3-methylpentanoic acid having either (2R,3R)- or (2S,3S)-configuration. FYPO_relaxed.owl CHEBI:17234 biolink:NamedThing glucose An aldohexose used as a source of energy and metabolic intermediate. FYPO_relaxed.owl CHEBI:33917 biolink:NamedThing aldohexose A hexose with a (potential) aldehyde group at one end. FYPO_relaxed.owl CHEBI:23628 biolink:NamedThing deoxyhexose Any C6 deoxy sugar having at least one hydroxy group replaced by hydrogen. FYPO_relaxed.owl CHEBI:17239 biolink:NamedThing CDP A pyrimidine ribonucleoside 5'-diphosphate having cytosine as the nucleobase. FYPO_relaxed.owl CHEBI:23521 biolink:NamedThing cytidine 5'-phosphate FYPO_relaxed.owl CHEBI:37039 biolink:NamedThing pyrimidine ribonucleoside 5'-diphosphate FYPO_relaxed.owl CHEBI:17258 biolink:NamedThing 7H-purine The 7H-tautomer of purine. FYPO_relaxed.owl CHEBI:35584 biolink:NamedThing purine A heterobicyclic aromatic organic compound comprising a pyrimidine ring fused to an imidazole ring; the parent compound of the purines. FYPO_relaxed.owl CHEBI:35586 biolink:NamedThing 1H-purine The 1H-tautomer of purine. FYPO_relaxed.owl CHEBI:35588 biolink:NamedThing 3H-purine The 3H-tautomer of purine. FYPO_relaxed.owl CHEBI:35589 biolink:NamedThing 9H-purine The 9H-tautomer of purine. FYPO_relaxed.owl CHEBI:17272 biolink:NamedThing propionate The conjugate base of propionic acid; a key precursor in lipid biosynthesis. FYPO_relaxed.owl CHEBI:17276 biolink:NamedThing phloretin A member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', 4' and 6'. FYPO_relaxed.owl CHEBI:71230 biolink:NamedThing dihydrochalcones Any ketone that is 1,3-diphenylpropanone and its derivatives obtained by substitution. FYPO_relaxed.owl CHEBI:71231 biolink:NamedThing dihydrochalcone A member of the class of dihydrochalcones that is acetophenone in which one of the hydrogens of the methyl group is replaced by a benzyl group. FYPO_relaxed.owl CHEBI:8113 biolink:NamedThing phlorizin An aryl beta-D-glucoside that is phloretin attached to a beta-D-glucopyranosyl residue at position 2' via a glycosidic linkage. FYPO_relaxed.owl CHEBI:25238 biolink:NamedThing methoxybenzoic acid Any benzoic acid carrying one or more methoxy substituents. FYPO_relaxed.owl CHEBI:30746 biolink:NamedThing benzoic acid A compound comprising a benzene ring core carrying a carboxylic acid substituent. FYPO_relaxed.owl CHEBI:35972 biolink:NamedThing dihydroxy monocarboxylic acid Any hydroxy monocarboxylic acid carrying at least two hydroxy groups. FYPO_relaxed.owl CHEBI:582124 biolink:NamedThing myriocin An amino acid-based antibiotic derived from certain thermophilic fungi; acts as a potent inhibitor of serine palmitoyltransferase, the first step in sphingosine biosynthesis. Myriocin also possesses immunosuppressant activity. FYPO_relaxed.owl CHEBI:37929 biolink:NamedThing xanthene dye A dye derived by condensation of phthalic anhydride with resorcinol (and derivatives) or m-aminophenol (and derivatives). FYPO_relaxed.owl CHEBI:3992 biolink:NamedThing cyclic ketone FYPO_relaxed.owl CHEBI:24789 biolink:NamedThing indanones FYPO_relaxed.owl CHEBI:36132 biolink:NamedThing alicyclic ketone A cyclic ketone in which the carbocyclic ring structure which may be saturated or unsaturated, but may not be a benzenoid or other aromatic system. FYPO_relaxed.owl CHEBI:52289 biolink:NamedThing wortmannin FYPO_relaxed.owl CHEBI:72581 biolink:NamedThing rotenones Members of the class of rotenoid which consists of a 6a,12a-dihydrochromeno[3,4-b]chromen-12(6H)-one skeleton and its substituted products. FYPO_relaxed.owl CHEBI:17296 biolink:NamedThing aniline A primary arylamine in which an amino functional group is substituted for one of the benzene hydrogens. FYPO_relaxed.owl CHEBI:17297 biolink:NamedThing UDP-sugar A pyrimidine nucleotide-sugar having UDP as the nucleotide component attached to an unspecified sugar via an anomeric diphosphate linkage. FYPO_relaxed.owl CHEBI:61109 biolink:NamedThing pyrimidine nucleotide-sugar A nucleotide-sugar whose nucleobase is a pyrimidine. FYPO_relaxed.owl CHEBI:17306 biolink:NamedThing maltose A glycosylglucose consisting of two D-glucopyranose units connected by an alpha-(1->4)-linkage. FYPO_relaxed.owl CHEBI:17593 biolink:NamedThing maltooligosaccharide A glucooligosaccharide derived from glucose monomers linked via alpha-D-1,4 bonds as in maltose. The term is commonly applied to the series of linear oligosaccharides composed of two, three, four, five and six such units of glucose. FYPO_relaxed.owl CHEBI:24405 biolink:NamedThing glycosylglucose FYPO_relaxed.owl CHEBI:17716 biolink:NamedThing lactose A glycosylglucose disaccharide, found most notably in milk, that consists of D-galactose and D-glucose fragments bonded through a beta-1->4 glycosidic linkage. The glucose fragment can be in either the alpha- or beta-pyranose form, whereas the galactose fragment can only have the beta-pyranose form. FYPO_relaxed.owl CHEBI:28053 biolink:NamedThing melibiose A glycosylglucose formed by an alpha-(1->6)-linkage between D-galactose and D-glucose. FYPO_relaxed.owl CHEBI:35222 biolink:NamedThing inhibitor A substance that diminishes the rate of a chemical reaction. FYPO_relaxed.owl CHEBI:70728 biolink:NamedThing actin polymerisation inhibitor Any substance that inhibits the polymerisation of the protein actin. FYPO_relaxed.owl CHEBI:38187 biolink:NamedThing pyridinecarbaldehyde FYPO_relaxed.owl CHEBI:17325 biolink:NamedThing 3-hydroxy-3-methylglutarate(2-) A dicarboxylic acid dianion that results from the removal of a proton from both of the carboxylic acid groups of 3-hydroxy-3-methylglutaric acid. FYPO_relaxed.owl CHEBI:67142 biolink:NamedThing nucleobase analogue A molecule that can substitute for a normal nucleobase in nucleic acids. FYPO_relaxed.owl CHEBI:46345 biolink:NamedThing 5-fluorouracil A nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine. It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth. FYPO_relaxed.owl CHEBI:53745 biolink:NamedThing 6-azauracil A 1,2,4-triazine compound having oxo-substituents at the 3- and 5-positions. FYPO_relaxed.owl CHEBI:74498 biolink:NamedThing 5-fluoroorotic acid A pyrimidinemonocarboxylic that is orotic acid which is substituted by fluorine at position 5. It is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate dicarboxylase. A yeast with and active URA3 gene converts 5-fluoroorotic acid to fluorodeoxyuridine, which is toxic to cells. FYPO_relaxed.owl CHEBI:17407 biolink:NamedThing 2-trans,6-trans-farnesyl diphosphate The trans,trans-stereoisomer of farnesyl diphosphate. FYPO_relaxed.owl CHEBI:39418 biolink:NamedThing straight-chain saturated fatty acid Any saturated fatty acid lacking a side-chain. FYPO_relaxed.owl CHEBI:28837 biolink:NamedThing octanoic acid A straight-chain saturated fatty acid that is heptane in which one of the hydrogens of a terminal methyl group has been replaced by a carboxy group. Octanoic acid is also known as caprylic acid. FYPO_relaxed.owl CHEBI:28842 biolink:NamedThing octadecanoic acid A C18 straight-chain saturated fatty acid component of many animal and vegetable lipids. As well as in the diet, it is used in hardening soaps, softening plastics and in making cosmetics, candles and plastics. FYPO_relaxed.owl CHEBI:28866 biolink:NamedThing tetracosanoic acid A C24 straight-chain saturated fatty acid. FYPO_relaxed.owl CHEBI:30772 biolink:NamedThing butyric acid A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group. FYPO_relaxed.owl CHEBI:30776 biolink:NamedThing hexanoic acid A C6, straight-chain saturated fatty acid. FYPO_relaxed.owl CHEBI:17422 biolink:NamedThing P(1),P(4)-bis(5'-adenosyl) tetraphosphate A diadenosyl tetraphosphate compound having the two 5'-adenosyl residues attached at the P(1)- and P(4)-positions. FYPO_relaxed.owl CHEBI:63738 biolink:NamedThing diadenosyl tetraphosphate A diadenosyl polyphosphate that consists of two adenosinyl moieties bridged by a tetraphosphate. FYPO_relaxed.owl CHEBI:17489 biolink:NamedThing 3',5'-cyclic AMP A 3',5'-cyclic purine nucleotide having having adenine as the nucleobase. FYPO_relaxed.owl CHEBI:19834 biolink:NamedThing 3',5'-cyclic purine nucleotide FYPO_relaxed.owl CHEBI:61296 biolink:NamedThing adenyl ribonucleotide A purine riboncleotide where adenine is the purine. FYPO_relaxed.owl CHEBI:22256 biolink:NamedThing adenosine phosphate FYPO_relaxed.owl CHEBI:17504 biolink:NamedThing 1-O-acyl-sn-glycero-3-phosphocholine(1+) FYPO_relaxed.owl CHEBI:17514 biolink:NamedThing cyanide A pseudohalide anion that is the conjugate base of hydrogen cyanide. FYPO_relaxed.owl CHEBI:36828 biolink:NamedThing pseudohalide anion FYPO_relaxed.owl CHEBI:40910 biolink:NamedThing azide anion FYPO_relaxed.owl CHEBI:17517 biolink:NamedThing phosphatidylglycerol A glycerophosphoglycerol that is glycerol in which the hydrogen of one of the primary hydroxy groups has been replaced by a phosphatidyl group. FYPO_relaxed.owl CHEBI:17522 biolink:NamedThing alditol A carbohydrate that is an acyclic polyol having the general formula HOCH2[CH(OH)]nCH2OH (formally derivable from an aldose by reduction of the carbonyl group). FYPO_relaxed.owl CHEBI:23639 biolink:NamedThing deoxy sugar Any sugar having a hydroxy group replaced with a hydrogen atom. FYPO_relaxed.owl CHEBI:33720 biolink:NamedThing carbohydrate acid FYPO_relaxed.owl CHEBI:50699 biolink:NamedThing oligosaccharide A compound in which monosaccharide units are joined by glycosidic linkages. The term is commonly used to refer to a defined structure as opposed to a polymer of unspecified length or a homologous mixture. When the linkages are of other types the compounds are regarded as oligosaccharide analogues. FYPO_relaxed.owl CHEBI:23451 biolink:NamedThing cyclitol A polyol consisting of a cycloalkane containing at least three hydroxy groups, each attached to a different ring carbon atom. FYPO_relaxed.owl CHEBI:27136 biolink:NamedThing triol A chemical compound containing three hydroxy groups. FYPO_relaxed.owl CHEBI:37206 biolink:NamedThing hexol A polyol that contains 6 hydroxy groups. FYPO_relaxed.owl CHEBI:59676 biolink:NamedThing nystatins A class of polyene antifungal antibiotics produced by Streptomyces noursei, and other Streptomyces species. FYPO_relaxed.owl CHEBI:7660 biolink:NamedThing nystatin A heterogeneous mixture of polyene compounds produced by cultures of Streptomyces noursei. It mainly consists of three biologically active components designated nystatin A1, nystatin A2, and nystatin A3. It is used to treat oral and dermal fungal infections. FYPO_relaxed.owl CHEBI:17544 biolink:NamedThing hydrogencarbonate The carbon oxoanion resulting from the removal of a proton from carbonic acid. FYPO_relaxed.owl CHEBI:41609 biolink:NamedThing carbonate FYPO_relaxed.owl CHEBI:17562 biolink:NamedThing cytidine A pyrimidine nucleoside in which cytosine is attached to ribofuranose via a beta-N(1)-glycosidic bond. FYPO_relaxed.owl CHEBI:23524 biolink:NamedThing cytidines FYPO_relaxed.owl CHEBI:38975 biolink:NamedThing methylbenzene Any alkylbenzene that is benzene substituted with one or more methyl groups. FYPO_relaxed.owl CHEBI:24268 biolink:NamedThing glucooligosaccharide An oligosaccharide comprised of glucose residues. FYPO_relaxed.owl CHEBI:4194 biolink:NamedThing D-hexose A hexose that has D-configuration at position 5. FYPO_relaxed.owl CHEBI:17620 biolink:NamedThing ferulic acid A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 3 and 4 respectively on the phenyl ring. FYPO_relaxed.owl CHEBI:37624 biolink:NamedThing L-glucose FYPO_relaxed.owl CHEBI:37661 biolink:NamedThing glucopyranose FYPO_relaxed.owl CHEBI:176497 biolink:NamedThing geroprotector Any compound that supports healthy aging, slows the biological aging process, or extends lifespan. FYPO_relaxed.owl CHEBI:50247 biolink:NamedThing antidote Any protective agent counteracting or neutralizing the action of poisons. FYPO_relaxed.owl CHEBI:62868 biolink:NamedThing hepatoprotective agent Any compound that is able to prevent damage to the liver. FYPO_relaxed.owl CHEBI:63726 biolink:NamedThing neuroprotective agent Any compound that can be used for the treatment of neurodegenerative disorders. FYPO_relaxed.owl CHEBI:66987 biolink:NamedThing radiation protective agent Any compound that is able to protect normal cells from the damage caused by radiation therapy. FYPO_relaxed.owl CHEBI:76595 biolink:NamedThing nephroprotective agent Any protective agent that is able to prevent damage to the kidney. FYPO_relaxed.owl CHEBI:77307 biolink:NamedThing cardioprotective agent Any protective agent that is able to prevent damage to the heart. FYPO_relaxed.owl CHEBI:17654 biolink:NamedThing electron acceptor A substance to which an electron may be transferred. FYPO_relaxed.owl CHEBI:39142 biolink:NamedThing Bronsted base A molecular entity capable of accepting a hydron from a donor (Bronsted acid). FYPO_relaxed.owl CHEBI:17668 biolink:NamedThing ribonucleoside diphosphate FYPO_relaxed.owl CHEBI:17955 biolink:NamedThing 2'-deoxyribonucleoside diphosphate FYPO_relaxed.owl CHEBI:26391 biolink:NamedThing purine nucleoside diphosphate FYPO_relaxed.owl CHEBI:26437 biolink:NamedThing pyrimidine nucleoside diphosphate FYPO_relaxed.owl CHEBI:176840 biolink:NamedThing vitamin B5 Any member of a group of vitamers that belong to the chemical structural class called pantothenic acids that exhibit biological activity against vitamin B5 deficiency. Deficiency of vitamin B5 is rare due to its widespread distribution in whole grain cereals, legumes and meat. Symptoms associated with vitamin B5 deficiency are difficult to asses since they are subtle and resemble those of other B vitamin deficiencies. The vitamers include (R)-pantothenic acid and its ionized and salt forms. FYPO_relaxed.owl CHEBI:36683 biolink:NamedThing organochlorine compound An organochlorine compound is a compound containing at least one carbon-chlorine bond. FYPO_relaxed.owl CHEBI:2639 biolink:NamedThing amiloride A member of the class of pyrazines resulting from the formal monoacylation of guanidine with the carboxy group of 3,5-diamino-6-chloropyrazine-2-carboxylic acid. FYPO_relaxed.owl CHEBI:27871 biolink:NamedThing chloroacetaldehyde Acetaldehyde substituted at C-2 by chlorine. FYPO_relaxed.owl CHEBI:28925 biolink:NamedThing mechlorethamine FYPO_relaxed.owl CHEBI:3647 biolink:NamedThing chlorpromazine A substituted phenothiazine in which the ring nitrogen at position 10 is attached to C-3 of an N,N-dimethylpropanamine moiety. FYPO_relaxed.owl CHEBI:51840 biolink:NamedThing chloroketone A ketone containing a chloro substituent. FYPO_relaxed.owl CHEBI:17710 biolink:NamedThing (R)-mevalonic acid The (R)-enantiomer of mevalonic acid. FYPO_relaxed.owl CHEBI:194519 biolink:NamedThing 3,5-dihydroxy-3-methylpentanoic acid A dihydroxy monocarboxylic acid comprising valeric acid having two hydroxy groups at the 3- and 5-positions together with a methyl group at the 3-position. FYPO_relaxed.owl CHEBI:28880 biolink:NamedThing (S)-mevalonic acid The (S)-enantiomer of mevalonic acid. FYPO_relaxed.owl CHEBI:177333 biolink:NamedThing organic tetracyclic compound FYPO_relaxed.owl CHEBI:51958 biolink:NamedThing organic polycyclic compound FYPO_relaxed.owl CHEBI:26606 biolink:NamedThing sapogenin Any organic polycyclic compound that is the aglycon moiety of a saponin; sapogenins may be steroids or triterpenoids. FYPO_relaxed.owl CHEBI:51286 biolink:NamedThing tetracenequinones FYPO_relaxed.owl CHEBI:51959 biolink:NamedThing organic tricyclic compound FYPO_relaxed.owl CHEBI:17748 biolink:NamedThing thymidine A pyrimidine 2'-deoxyribonucleoside having thymine as the nucleobase. FYPO_relaxed.owl CHEBI:19255 biolink:NamedThing pyrimidine 2'-deoxyribonucleoside FYPO_relaxed.owl CHEBI:60761 biolink:NamedThing floxuridine A pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract. FYPO_relaxed.owl CHEBI:63624 biolink:NamedThing telbivudine A pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase. FYPO_relaxed.owl CHEBI:17754 biolink:NamedThing glycerol A triol with a structure of propane substituted at positions 1, 2 and 3 by hydroxy groups. FYPO_relaxed.owl CHEBI:24583 biolink:NamedThing hexitol FYPO_relaxed.owl CHEBI:24402 biolink:NamedThing glycosphingolipid A glycosphingolipid is a glycolipid that is a carbohydrate-containing derivative of a sphingoid or ceramide. It is understood that the carbohydrate residue is attached by a glycosidic linkage to O-1 of the sphingoid. FYPO_relaxed.owl CHEBI:35785 biolink:NamedThing sphingoid Sphinganine, its homologs and stereoisomers, and the hydroxy and unsaturated derivatives of these compounds. FYPO_relaxed.owl CHEBI:35786 biolink:NamedThing phosphosphingolipid FYPO_relaxed.owl CHEBI:177898 biolink:NamedThing omega-carboxy-(fatty acyl)-CoA(5-) An acyl-CoA oxoanion obtained by deprotonation of the phosphate, diphosphate and carboxy groups of any omega-carboxy-(fatty acyl)-CoA; major species at pH 7.3. FYPO_relaxed.owl CHEBI:35748 biolink:NamedThing fatty acid ester A carboxylic ester in which the carboxylic acid component can be any fatty acid. FYPO_relaxed.owl CHEBI:17792 biolink:NamedThing organohalogen compound A compound containing at least one carbon-halogen bond (where X is a halogen atom). FYPO_relaxed.owl CHEBI:24532 biolink:NamedThing organic heterocyclic compound A cyclic compound having as ring members atoms of carbon and at least of one other element. FYPO_relaxed.owl CHEBI:25710 biolink:NamedThing organophosphorus compound An organophosphorus compound is formally a compound containing at least one carbon-phosphorus bond, but the term is often extended to include esters and thioesters. FYPO_relaxed.owl CHEBI:36962 biolink:NamedThing organochalcogen compound An organochalcogen compound is a compound containing at least one carbon-chalcogen bond. FYPO_relaxed.owl CHEBI:86478 biolink:NamedThing antibiotic antifungal agent Heteroorganic entities that are microbial metabolites (or compounds derived from them) which have significant antifungal properties. FYPO_relaxed.owl CHEBI:37578 biolink:NamedThing halide Any heteroatomic molecular entity that is a chemical compound of halogen with other chemical elements. FYPO_relaxed.owl CHEBI:33958 biolink:NamedThing halide salt FYPO_relaxed.owl CHEBI:17815 biolink:NamedThing 1,2-diacyl-sn-glycerol FYPO_relaxed.owl CHEBI:49172 biolink:NamedThing 1,2-diglyceride FYPO_relaxed.owl CHEBI:75524 biolink:NamedThing 2,3-diacyl-sn-glycerol A 1,2-diglyceride with acyl groups at positions 2 and 3 of the sn-glycerol. FYPO_relaxed.owl CHEBI:17855 biolink:NamedThing triglyceride Any glyceride resulting from the condensation of all three hydroxy groups of glycerol (propane-1,2,3-triol) with fatty acids. FYPO_relaxed.owl CHEBI:47778 biolink:NamedThing glyceride Any ester resulting from the condensation of one or more of the hydroxy groups of glycerol (propane-1,2,3-triol) with fatty acids. FYPO_relaxed.owl CHEBI:18035 biolink:NamedThing diglyceride A glyceride that is glycerol in which any two of the hydroxy groups have been acylated. In the structure shown, two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group. FYPO_relaxed.owl CHEBI:76579 biolink:NamedThing triradylglycerol A glycerol compound having one of three possible substituent groups - either acyl, alkyl, or alk-1-enyl - at each of the three possible positions sn-1, sn-2 or sn-3. has functional parent glycerol (CHEBI:17754), children: triglyceride (CHEBI:17855). Parent: is_a glycerolipid (CHEBI:35741) FYPO_relaxed.owl CHEBI:17858 biolink:NamedThing glutathione disulfide FYPO_relaxed.owl CHEBI:50091 biolink:NamedThing S-nitrosoglutathione A glutathione derivative that is glutathione in which the hydrogen attached to the sulfur has been replaced by a nitroso group. FYPO_relaxed.owl CHEBI:23117 biolink:NamedThing chlorine molecular entity A halogen molecular entity containing one or more atoms of chlorine. FYPO_relaxed.owl CHEBI:23114 biolink:NamedThing chloride salt FYPO_relaxed.owl CHEBI:33426 biolink:NamedThing chlorine oxoacid FYPO_relaxed.owl CHEBI:33431 biolink:NamedThing elemental chlorine FYPO_relaxed.owl CHEBI:33437 biolink:NamedThing chlorine oxoanion FYPO_relaxed.owl CHEBI:17920 biolink:NamedThing 3-methyleneoxindole FYPO_relaxed.owl CHEBI:38459 biolink:NamedThing oxindoles Any member of the class of indolones whose structure is based on an oxindole (2-indolone) skeleton. FYPO_relaxed.owl CHEBI:17968 biolink:NamedThing butyrate A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:33432 biolink:NamedThing monoatomic chlorine FYPO_relaxed.owl CHEBI:76578 biolink:NamedThing diradylglycerol Any lipid that is glycerol bearing two substituent groups - either acyl, alkyl, or alk-1-enyl - at any two of the three possible positions. FYPO_relaxed.owl CHEBI:18075 biolink:NamedThing dTDP A thymidine phosphate having a diphosphate group at the 5'-position. FYPO_relaxed.owl CHEBI:37037 biolink:NamedThing pyrimidine 2'-deoxyribonucleoside 5'-diphosphate FYPO_relaxed.owl CHEBI:18087 biolink:NamedThing myo-inositol polyphosphate FYPO_relaxed.owl CHEBI:25448 biolink:NamedThing myo-inositol phosphate An inositol phosphate in which the inositol component has myo-configuration. FYPO_relaxed.owl CHEBI:65212 biolink:NamedThing polysaccharide derivative A carbohydrate derivative that is any derivative of a polysaccharide. FYPO_relaxed.owl CHEBI:72813 biolink:NamedThing exopolysaccharide A biomacromolecule composed of carbohydrate residues which is secreted by a microorganism into the surrounding environment. FYPO_relaxed.owl CHEBI:18170 biolink:NamedThing selenic acid FYPO_relaxed.owl CHEBI:33489 biolink:NamedThing selenium oxoacid FYPO_relaxed.owl CHEBI:26642 biolink:NamedThing selenous acid FYPO_relaxed.owl CHEBI:33856 biolink:NamedThing aromatic amino acid An amino acid whose structure includes an aromatic ring. FYPO_relaxed.owl CHEBI:18222 biolink:NamedThing xylose An aldopentose, found in the embryos of most edible plants and used in medicine to test for malabsorption by administration in water to the patient. FYPO_relaxed.owl CHEBI:33916 biolink:NamedThing aldopentose A pentose with a (potential) aldehyde group at one end. FYPO_relaxed.owl CHEBI:22599 biolink:NamedThing arabinose FYPO_relaxed.owl CHEBI:18231 biolink:NamedThing arsenic acid An arsenic oxoacid comprising one oxo group and three hydroxy groups attached to a central arsenic atom. FYPO_relaxed.owl CHEBI:33407 biolink:NamedThing arsenic oxoacid FYPO_relaxed.owl CHEBI:18248 biolink:NamedThing iron atom An iron group element atom that has atomic number 26. FYPO_relaxed.owl CHEBI:33356 biolink:NamedThing iron group element atom FYPO_relaxed.owl CHEBI:18254 biolink:NamedThing ribonucleoside Any nucleoside where the sugar component is D-ribose. FYPO_relaxed.owl CHEBI:23636 biolink:NamedThing deoxyribonucleoside FYPO_relaxed.owl CHEBI:26394 biolink:NamedThing purine nucleoside FYPO_relaxed.owl CHEBI:26440 biolink:NamedThing pyrimidine nucleoside FYPO_relaxed.owl CHEBI:64228 biolink:NamedThing tunicamycin A0 A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 11-methyldodec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. FYPO_relaxed.owl CHEBI:64245 biolink:NamedThing tunicamycin A1 A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 12-methyltridec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. FYPO_relaxed.owl CHEBI:64246 biolink:NamedThing tunicamycin A2 A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a tetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. FYPO_relaxed.owl CHEBI:64248 biolink:NamedThing tunicamycin B1 A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a pentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. FYPO_relaxed.owl CHEBI:64250 biolink:NamedThing tunicamycin B2 A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 13-methyltetradec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. FYPO_relaxed.owl CHEBI:64255 biolink:NamedThing tunicamycin B3 A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by an 13-methyltetradecanoyl fatty acyl substituent on the amino group of the tunicamine moiety. FYPO_relaxed.owl CHEBI:64256 biolink:NamedThing tunicamycin C1 A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 14-methylpentadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. FYPO_relaxed.owl CHEBI:64257 biolink:NamedThing tunicamycin C2 A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a hexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. FYPO_relaxed.owl CHEBI:64271 biolink:NamedThing tunicamycin D1 A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a heptadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. FYPO_relaxed.owl CHEBI:64272 biolink:NamedThing tunicamycin D2 A nucleoside that is one of the homologues in the mixture that is tunicamycin, characterised by a 15-methylhexadec-2-enoyl fatty acyl substituent on the amino group of the tunicamine moiety. FYPO_relaxed.owl CHEBI:47019 biolink:NamedThing dihydroxytetrahydrofuran FYPO_relaxed.owl CHEBI:18274 biolink:NamedThing 2'-deoxyribonucleoside FYPO_relaxed.owl CHEBI:36987 biolink:NamedThing 3'-deoxyribonucleoside FYPO_relaxed.owl CHEBI:60173 biolink:NamedThing purine deoxyribonucleoside A deoxyribonucleoside containing a purine base. FYPO_relaxed.owl CHEBI:68472 biolink:NamedThing pyrimidine deoxyribonucleoside A deoxyribonucleoside containing a pyrimidine base. FYPO_relaxed.owl CHEBI:47018 biolink:NamedThing monohydroxytetrahydrofuran FYPO_relaxed.owl CHEBI:19260 biolink:NamedThing 2'-deoxyribonucleotide FYPO_relaxed.owl CHEBI:18282 biolink:NamedThing nucleobase That part of DNA or RNA that may be involved in pairing. FYPO_relaxed.owl CHEBI:22715 biolink:NamedThing benzimidazoles An organic heterocyclic compound containing a benzene ring fused to an imidazole ring. FYPO_relaxed.owl CHEBI:22728 biolink:NamedThing benzopyrrole FYPO_relaxed.owl CHEBI:25558 biolink:NamedThing organonitrogen heterocyclic antibiotic FYPO_relaxed.owl CHEBI:26144 biolink:NamedThing piperazines FYPO_relaxed.owl CHEBI:26151 biolink:NamedThing piperidines FYPO_relaxed.owl CHEBI:26373 biolink:NamedThing pteridines FYPO_relaxed.owl CHEBI:26421 biolink:NamedThing pyridines Any organonitrogen heterocyclic compound based on a pyridine skeleton and its substituted derivatives. FYPO_relaxed.owl CHEBI:26513 biolink:NamedThing quinolines A class of aromatic heterocyclic compounds each of which contains a benzene ring ortho fused to carbons 2 and 3 of a pyridine ring. FYPO_relaxed.owl CHEBI:35622 biolink:NamedThing thiazolidines FYPO_relaxed.owl CHEBI:35676 biolink:NamedThing benzazepine A group of two-ring heterocyclic compounds consisting of a benzene ring fused to an azepine ring. FYPO_relaxed.owl CHEBI:35875 biolink:NamedThing imidazopyrimidine FYPO_relaxed.owl CHEBI:37949 biolink:NamedThing azacycloalkane FYPO_relaxed.owl CHEBI:38077 biolink:NamedThing polypyrrole A compound composed of two or more pyrrole units. FYPO_relaxed.owl CHEBI:38260 biolink:NamedThing pyrrolidines Any of a class of heterocyclic amines having a saturated five-membered ring. FYPO_relaxed.owl CHEBI:38295 biolink:NamedThing azabicycloalkane FYPO_relaxed.owl CHEBI:38303 biolink:NamedThing azirinopyrroloindole FYPO_relaxed.owl CHEBI:38313 biolink:NamedThing diazines Any organic heterocyclic compound containing a benzene ring in which two of the C-H fragments have been replaced by isolobal nitrogens (the diazine parent structure). FYPO_relaxed.owl CHEBI:38669 biolink:NamedThing pyrazolopyrimidine FYPO_relaxed.owl CHEBI:38777 biolink:NamedThing azetidines FYPO_relaxed.owl CHEBI:46952 biolink:NamedThing oxazinane FYPO_relaxed.owl CHEBI:48337 biolink:NamedThing pyrrolopyrazine FYPO_relaxed.owl CHEBI:48626 biolink:NamedThing pyranoindolizinoquinoline FYPO_relaxed.owl CHEBI:50511 biolink:NamedThing bipyridines Compounds containing a bipyridine group. FYPO_relaxed.owl CHEBI:50893 biolink:NamedThing azaarene FYPO_relaxed.owl CHEBI:68452 biolink:NamedThing azole Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen. FYPO_relaxed.owl CHEBI:73539 biolink:NamedThing naphthyridine derivative Any organonitrogen heterocyclic compound that is a derivative of a naphthyridine. FYPO_relaxed.owl CHEBI:18283 biolink:NamedThing alpha,alpha-trehalose 6-phosphate FYPO_relaxed.owl CHEBI:27084 biolink:NamedThing trehalose phosphate FYPO_relaxed.owl CHEBI:18291 biolink:NamedThing manganese atom FYPO_relaxed.owl CHEBI:33352 biolink:NamedThing manganese group element atom FYPO_relaxed.owl CHEBI:18300 biolink:NamedThing maleic acid A butenedioic acid in which the double bond has cis- (Z)-configuration. FYPO_relaxed.owl CHEBI:18303 biolink:NamedThing phosphatidyl-L-serine A class of aminophospholipids in which a phosphatidyl group is esterified to the hydroxy group of serine. FYPO_relaxed.owl CHEBI:52565 biolink:NamedThing acylglycerophosphoserine FYPO_relaxed.owl CHEBI:84135 biolink:NamedThing L-serine derivative A proteinogenic amino acid derivative resulting from reaction of L-serine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-serine by a heteroatom. FYPO_relaxed.owl CHEBI:18307 biolink:NamedThing UDP-D-galactose A UDP-sugar having D-galactose as the sugar component. FYPO_relaxed.owl CHEBI:18308 biolink:NamedThing acrylic acid A alpha,beta-unsaturated monocarboxylic acid that is ethene substituted by a carboxy group. FYPO_relaxed.owl CHEBI:39157 biolink:NamedThing trichostatic acid FYPO_relaxed.owl CHEBI:18310 biolink:NamedThing alkane An acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, and therefore consisting entirely of hydrogen atoms and saturated carbon atoms. FYPO_relaxed.owl CHEBI:24632 biolink:NamedThing hydrocarbon A compound consisting of carbon and hydrogen only. FYPO_relaxed.owl CHEBI:33663 biolink:NamedThing cyclic hydrocarbon FYPO_relaxed.owl CHEBI:35186 biolink:NamedThing terpene A hydrocarbon of biological origin having carbon skeleton formally derived from isoprene [CH2=C(CH3)CH=CH2]. FYPO_relaxed.owl CHEBI:33654 biolink:NamedThing alicyclic compound An aliphatic compound having a carbocyclic ring structure which may be saturated or unsaturated, but may not be a benzenoid or other aromatic system. FYPO_relaxed.owl CHEBI:18319 biolink:NamedThing SAICAR A 1-(phosphoribosyl)imidazolecarboxamide resulting from the formal condesation of the darboxy group of 5-amino-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid with the amino group of L-aspartic acid. FYPO_relaxed.owl CHEBI:37290 biolink:NamedThing 1-(phosphoribosyl)imidazolecarboxamide FYPO_relaxed.owl CHEBI:18406 biolink:NamedThing AICA ribonucleotide A 1-(phosphoribosyl)imidazolecarboxamide that is acadesine in which the hydroxy group at the 5' position has been converted to its monophosphate derivative. FYPO_relaxed.owl CHEBI:18320 biolink:NamedThing 1,4-dithiothreitol The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol. FYPO_relaxed.owl CHEBI:18367 biolink:NamedThing phosphate(3-) A phosphate ion that is the conjugate base of hydrogenphosphate. FYPO_relaxed.owl CHEBI:79387 biolink:NamedThing trivalent inorganic anion Any inorganic anion with a valency of three. FYPO_relaxed.owl CHEBI:46442 biolink:NamedThing vanadate(3-) A vanadium oxoanion that is a trianion with formula VO4 in which the vanadium is in the +5 oxidation state and is attached to four oxygen atoms. FYPO_relaxed.owl CHEBI:18375 biolink:NamedThing nucleoside 3',5'-cyclic phosphate A ribosyl or deoxyribosyl derivative of a pyrimidine or purine base in which C-3 and C-5 of the ribose ring are engaged in formation of a cyclic mono-, di-, tri- or tetra-phosphate. FYPO_relaxed.owl CHEBI:23447 biolink:NamedThing cyclic nucleotide FYPO_relaxed.owl CHEBI:36982 biolink:NamedThing cyclic purine nucleotide FYPO_relaxed.owl CHEBI:18379 biolink:NamedThing nitrile A compound having the structure RC#N; thus a C-substituted derivative of hydrocyanic acid, HC#N. In systematic nomenclature, the suffix nitrile denotes the triply bound #N atom, not the carbon atom attached to it. FYPO_relaxed.owl CHEBI:18391 biolink:NamedThing D-gluconate A gluconate having D-configuration. FYPO_relaxed.owl CHEBI:24265 biolink:NamedThing gluconate FYPO_relaxed.owl CHEBI:28498 biolink:NamedThing acadesine A 1-ribosylimidazolecarboxamide in which the carboxamide group is situated at position 4 of the imidazole ring, which is further substituted at position 5 by an amino group. A purine nucleoside analogue and activator of AMP-activated protein kinase, it is is used for the treatment of acute lymphoblastic leukemia and is reported to have cardioprotective effects. FYPO_relaxed.owl CHEBI:18420 biolink:NamedThing magnesium(2+) FYPO_relaxed.owl CHEBI:30412 biolink:NamedThing monoatomic dication FYPO_relaxed.owl CHEBI:29108 biolink:NamedThing calcium(2+) FYPO_relaxed.owl CHEBI:48828 biolink:NamedThing cobalt(2+) FYPO_relaxed.owl CHEBI:39127 biolink:NamedThing magnesium cation Any magnesium ion that is positively charged. FYPO_relaxed.owl CHEBI:60240 biolink:NamedThing divalent metal cation A metal cation with a valence of two. FYPO_relaxed.owl CHEBI:18421 biolink:NamedThing superoxide FYPO_relaxed.owl CHEBI:33263 biolink:NamedThing diatomic oxygen FYPO_relaxed.owl CHEBI:36876 biolink:NamedThing inorganic radical anion FYPO_relaxed.owl CHEBI:30199 biolink:NamedThing trioxidosilicate(.1-) FYPO_relaxed.owl CHEBI:187892 biolink:NamedThing benzamidine(1+) A carboxamidinium ion obtained by protonation of the amidino group of benzamidine. Major species at pH 7.3. FYPO_relaxed.owl CHEBI:77718 biolink:NamedThing carboxamidinium ion Any iminium ion resulting from the protonation of a carboxamidine. FYPO_relaxed.owl CHEBI:18790 biolink:NamedThing (S)-mevalonate The (S)-enantiomer of mevalonate. FYPO_relaxed.owl CHEBI:194520 biolink:NamedThing 3,5-dihydroxy-3-methylpentanoate A hydroxy monocarboxylic acid anion that is the conjugate base of 3,5-dihydroxy-3-methylpentanoic acid resulting from the deprotonation of the carboxy group; Major species at pH 7.3. FYPO_relaxed.owl CHEBI:36464 biolink:NamedThing (R)-mevalonate The (R)-enantiomer of mevalonate. FYPO_relaxed.owl CHEBI:18946 biolink:NamedThing delta-lactone A lactone having a six-membered lactone ring. FYPO_relaxed.owl CHEBI:25000 biolink:NamedThing lactone Any cyclic carboxylic ester containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring. FYPO_relaxed.owl CHEBI:35213 biolink:NamedThing cyclodepsipeptide A depsipeptide in which the amino and hydroxy carboxylic acid residues are connected in a ring. FYPO_relaxed.owl CHEBI:37668 biolink:NamedThing terpene lactone FYPO_relaxed.owl CHEBI:63944 biolink:NamedThing macrocyclic lactone Any lactone in which the cyclic carboxylic ester group forms a part of a cyclic macromolecule. FYPO_relaxed.owl CHEBI:189750 biolink:NamedThing Ophthalmate FYPO_relaxed.owl CHEBI:48030 biolink:NamedThing tetrapeptide Any molecule that contains four amino-acid residues connected by peptide linkages. FYPO_relaxed.owl CHEBI:64120 biolink:NamedThing M-factor A nine-membered oligopeptide that consists of tyrosyl, threonyl, prolyl, lysyl, valyl, prolyl, tyrosyl, methionyl and methyl S-farnesylcysteinate residues joined in sequence. A peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Minus. FYPO_relaxed.owl CHEBI:190297 biolink:NamedThing inorganic magnesium salt A magnesium salt that lacks C-H bonds FYPO_relaxed.owl CHEBI:190303 biolink:NamedThing inorganic potassium salt A potassium salt that lacks C-H bonds FYPO_relaxed.owl CHEBI:24839 biolink:NamedThing inorganic salt FYPO_relaxed.owl CHEBI:36093 biolink:NamedThing inorganic chloride FYPO_relaxed.owl CHEBI:38702 biolink:NamedThing inorganic sodium salt FYPO_relaxed.owl CHEBI:51084 biolink:NamedThing inorganic nitrate salt FYPO_relaxed.owl CHEBI:26218 biolink:NamedThing potassium salt Any alkali metal salt having potassium(1+) as the cation. FYPO_relaxed.owl CHEBI:63043 biolink:NamedThing potassium nitrate The inorganic nitrate salt of potassium. FYPO_relaxed.owl CHEBI:19203 biolink:NamedThing 1H-pyrrole A tautomer of pyrrole that has the double bonds at positions 2 and 4. FYPO_relaxed.owl CHEBI:32863 biolink:NamedThing secondary amine A compound formally derived from ammonia by replacing two hydrogen atoms by hydrocarbyl groups. FYPO_relaxed.owl CHEBI:35556 biolink:NamedThing pyrrole A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'. FYPO_relaxed.owl CHEBI:35557 biolink:NamedThing 3H-pyrrole That one of the three tautomers of pyrrole which has the double bonds at positions 1 and 4. FYPO_relaxed.owl CHEBI:35558 biolink:NamedThing 2H-pyrrole That one of the three tautomers of pyrrole which has the double bonds at positions 1 and 3. FYPO_relaxed.owl CHEBI:19239 biolink:NamedThing 2'-deoxyadenosine phosphate FYPO_relaxed.owl CHEBI:23612 biolink:NamedThing deoxyadenosine phosphate FYPO_relaxed.owl CHEBI:19569 biolink:NamedThing 2-deoxyribose phosphate A deoxyaldopentose phosphate in which the deoxyaldopentose is 2-deoxyribose. FYPO_relaxed.owl CHEBI:4431 biolink:NamedThing deoxyribonucleotide A nucleotide in which the ribose moiety has one or more of its hydroxy groups substituted by hydrogen. FYPO_relaxed.owl CHEBI:192714 biolink:NamedThing an N(4)-(oligosaccharide-(1->3)-[oligosaccharide-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc)-L-asparaginyl residue FYPO_relaxed.owl CHEBI:192979 biolink:NamedThing nystatin A2 FYPO_relaxed.owl CHEBI:31927 biolink:NamedThing nystatin A3 FYPO_relaxed.owl CHEBI:473992 biolink:NamedThing nystatin A1 A polyene macrolide antibiotic; part of the nystatin complex produced by several Streptomyces species. It is an antifungal antibiotic used for the treatment of topical fungal infections caused by a broad spectrum of fungal pathogens comprising yeast-like and filamentous species. FYPO_relaxed.owl CHEBI:193151 biolink:NamedThing D-isoleucine zwitterion An alpha-amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of D-isoleucine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:78608 biolink:NamedThing alpha-amino acid zwitterion An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any alpha-amino acid; major species at pH 7.3. FYPO_relaxed.owl CHEBI:19324 biolink:NamedThing 2,3-bisphosphoglycerate FYPO_relaxed.owl CHEBI:33871 biolink:NamedThing glycerate A hydroxy monocarboxylic acid anion that is the conjugate base of glyceric acid, obtained by deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:195255 biolink:NamedThing gentamicin X2 cation (4+) Major microspecies at pH 7.3. FYPO_relaxed.owl CHEBI:195256 biolink:NamedThing geneticin cation(4+) Major microspecies at pH 7.3. FYPO_relaxed.owl CHEBI:23634 biolink:NamedThing deoxyaldopentose phosphate FYPO_relaxed.owl CHEBI:61902 biolink:NamedThing hydroxy fatty acyl-CoA A fatty-acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of any hydroxy fatty acid. FYPO_relaxed.owl CHEBI:35662 biolink:NamedThing terpenoid fundamental parent FYPO_relaxed.owl CHEBI:2038 biolink:NamedThing 5-azacytidine An N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-ribofuranosyl residue via an N-glycosidic linkage. An antineoplastic agent, it is used in the treatment of myeloid leukaemia. FYPO_relaxed.owl CHEBI:48009 biolink:NamedThing N-glycosyl-1,3,5-triazine FYPO_relaxed.owl CHEBI:60783 biolink:NamedThing nucleoside analogue An analogue of a nucleoside, being an N-glycosyl compound in which the nitrogen-containing moiety is a modified nucleotide base. They are commonly used as antiviral products to prevent viral replication in infected cells. FYPO_relaxed.owl CHEBI:63581 biolink:NamedThing stavudine A nucleoside analogue obtained by formal dehydration across positions 2 and 3 of thymidine. An inhibitor of HIV-1 reverse transcriptase FYPO_relaxed.owl CHEBI:20652 biolink:NamedThing 5alpha-ergostane FYPO_relaxed.owl CHEBI:35512 biolink:NamedThing ergostane FYPO_relaxed.owl CHEBI:22527 biolink:NamedThing aminopurine Any purine having at least one amino substituent. FYPO_relaxed.owl CHEBI:38001 biolink:NamedThing 2,6-diaminopurines Any aminopurine that has amino substituents at positions 2 and 6, and their substituted derivatives. FYPO_relaxed.owl CHEBI:20854 biolink:NamedThing ATP synthase inhibitor A mitochondrial respiratory-chain inhibitor that interferes with the action of ATP synthase. FYPO_relaxed.owl CHEBI:25355 biolink:NamedThing mitochondrial respiratory-chain inhibitor FYPO_relaxed.owl CHEBI:38498 biolink:NamedThing mitochondrial NADH:ubiquinone reductase inhibitor FYPO_relaxed.owl CHEBI:38500 biolink:NamedThing EC 1.9.3.1 (cytochrome c oxidase) inhibitor An EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor that interferes with the action of cytochrome c oxidase (EC 1.9.3.1). FYPO_relaxed.owl CHEBI:73216 biolink:NamedThing EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor Any hydrolase inhibitor that interferes with the action of a hydrolase which acts on acid anhydrides (EC 3.6.*.*). FYPO_relaxed.owl CHEBI:76895 biolink:NamedThing EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor An EC 3.6.* (hydrolases acting on acid anhydrides) inhibitor that interferes with the action of any such enzyme that catalyses transmembrane movement of substances (EC 3.6.3.*). FYPO_relaxed.owl CHEBI:20857 biolink:NamedThing C-glycosyl compound A glycosyl compound arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to a carbon atom, thus creating a C-C bond. FYPO_relaxed.owl CHEBI:63161 biolink:NamedThing glycosyl compound A carbohydrate derivative arising formally from the elimination of water from a glycosidic hydroxy group and an H atom bound to an oxygen, carbon, nitrogen or sulfur atom of a separate entity. FYPO_relaxed.owl CHEBI:24400 biolink:NamedThing glycoside A glycosyl compound resulting from the attachment of a glycosyl group to a non-acyl group RO-, RS-, RSe-, etc. The bond between the glycosyl group and the non-acyl group is called a glycosidic bond. By extension, the terms N-glycosides and C-glycosides are used as class names for glycosylamines and for compounds having a glycosyl group attached to a hydrocarbyl group respectively. These terms are misnomers and should not be used. The preferred terms are glycosylamines and C-glycosyl compounds, respectively. FYPO_relaxed.owl CHEBI:26562 biolink:NamedThing ribose phosphate FYPO_relaxed.owl CHEBI:26561 biolink:NamedThing ribonucleotide FYPO_relaxed.owl CHEBI:37292 biolink:NamedThing 1-(phosphoribosyl)imidazole FYPO_relaxed.owl CHEBI:21313 biolink:NamedThing L-glutamyl ester Any alpha-amino acid ester that is the ester of L-glutamic acid. FYPO_relaxed.owl CHEBI:46874 biolink:NamedThing alpha-amino acid ester The amino acid ester derivative obtained the formal condensation of an alpha-amino acid with an alcohol. FYPO_relaxed.owl CHEBI:83982 biolink:NamedThing L-glutamic acid derivative A proteinogenic amino acid derivative resulting from reaction of L-glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen of L-glutamic acid by a heteroatom. FYPO_relaxed.owl CHEBI:24317 biolink:NamedThing L-glutamine derivative A proteinogenic amino acid derivative resulting from reaction of L-glutamine at the amino group, the carboxy group, or the carboxamide, or from the replacement of any hydrogen of L-glutamine by a heteroatom. FYPO_relaxed.owl CHEBI:21501 biolink:NamedThing N-acetyl-D-amino acid An N-acetyl-amino acid having D-configuration. FYPO_relaxed.owl CHEBI:21545 biolink:NamedThing N-acetyl-L-amino acid An L-amino acid having an N-acetyl substituent. FYPO_relaxed.owl CHEBI:22195 biolink:NamedThing acetyl-amino acid Any amino acid derivative that is the N-acetyl or O-acetyl derivative of an amino acid. FYPO_relaxed.owl CHEBI:21760 biolink:NamedThing N-methyl-amino acid An amino acid derivative in which at least one of the hydrogens of the amino group has been replaced by a methyl group. FYPO_relaxed.owl CHEBI:23509 biolink:NamedThing cysteine derivative An amino acid derivative resulting from reaction of cysteine at the amino group, carboxy group, or thiol group, or from the replacement of any hydrogen of cysteine by a heteroatom. The definition normally excludes peptides containing cysteine residues. FYPO_relaxed.owl CHEBI:24315 biolink:NamedThing glutamic acid derivative An amino acid derivative resulting from reaction of glutamic acid at the amino group or either of the carboxy groups, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing glutamic acid residues. FYPO_relaxed.owl CHEBI:24599 biolink:NamedThing histidine derivative An amino acid derivative resulting from reaction of histidine at the amino group or the carboxy group, or from the replacement of any hydrogen of histidine by a heteroatom. The definition normally excludes peptides containing alanine residues. FYPO_relaxed.owl CHEBI:25985 biolink:NamedThing phenylalanine derivative An amino acid derivative resulting from reaction of alanine at the amino group or the carboxy group, or from the replacement of any hydrogen of phenylalanine by a heteroatom. The definition normally excludes peptides containing phenylalanine residues. FYPO_relaxed.owl CHEBI:26649 biolink:NamedThing serine derivative An amino acid derivative resulting from reaction of serine at the amino group or the carboxy group, or from the replacement of any hydrogen of serine by a heteroatom. The definition normally excludes peptides containing serine residues. FYPO_relaxed.owl CHEBI:46668 biolink:NamedThing amino acid ester Any carboxylic ester derivative of an amino acid. FYPO_relaxed.owl CHEBI:53079 biolink:NamedThing lysine derivative An amino acid derivative resulting from reaction of lysine at the amino group or the carboxy group, or from the replacement of any hydrogen of lysine by a heteroatom. The definition normally excludes peptides containing lysine residues. FYPO_relaxed.owl CHEBI:83811 biolink:NamedThing proteinogenic amino acid derivative Any derivative of a proteinogenic amino acid resulting from reaction at an amino group, carboxy group, or a side-chain functional group, or from the replacement of any hydrogen by a heteroatom. FYPO_relaxed.owl CHEBI:22102 biolink:NamedThing UDP-D-glucosamine FYPO_relaxed.owl CHEBI:22193 biolink:NamedThing acetyl-L-lysine An N-acetyl-L-amino acid that is the N-acetyl derivative of L-lysine. FYPO_relaxed.owl CHEBI:25095 biolink:NamedThing L-lysine derivative A proteinogenic amino acid derivative resulting from reaction of L-lysine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-lysine by a heteroatom. FYPO_relaxed.owl CHEBI:22211 biolink:NamedThing aconitic acid A tricarboxylic acid that is prop-1-ene substituted by carboxy groups at positions 1, 2 and 3. FYPO_relaxed.owl CHEBI:27093 biolink:NamedThing tricarboxylic acid An oxoacid containing three carboxy groups. FYPO_relaxed.owl CHEBI:30769 biolink:NamedThing citric acid A tricarboxylic acid that is propane-1,2,3-tricarboxylic acid bearing a hydroxy substituent at position 2. It is an important metabolite in the pathway of all aerobic organisms. FYPO_relaxed.owl CHEBI:22221 biolink:NamedThing acyl group An organic group formed by removing one or more hydroxy groups from an oxoacid that has the general structure RkE(=O)l(OH)m (l =/= 0). Although the term is almost always applied to organic compounds, with carboxylic acid as the oxoacid, acyl groups can in principle be derived from other types of acids such as sulfonic acids or phosphonic acids. FYPO_relaxed.owl CHEBI:33708 biolink:NamedThing amino-acid residue When two or more amino acids combine to form a peptide, the elements of water are removed, and what remains of each amino acid is called an amino-acid residue. FYPO_relaxed.owl CHEBI:50319 biolink:NamedThing nucleotide residue FYPO_relaxed.owl CHEBI:50320 biolink:NamedThing nucleoside residue FYPO_relaxed.owl CHEBI:51446 biolink:NamedThing organic divalent group FYPO_relaxed.owl CHEBI:51447 biolink:NamedThing organic univalent group FYPO_relaxed.owl CHEBI:52845 biolink:NamedThing cyclic organic group An organic group that consists of a closed ring. It may be a substituent or a skeleton. FYPO_relaxed.owl CHEBI:22251 biolink:NamedThing adenosine bisphosphate FYPO_relaxed.owl CHEBI:61078 biolink:NamedThing purine nucleoside bisphosphate A nucleoside bisphosphate that has a purine nucleobase. FYPO_relaxed.owl CHEBI:61079 biolink:NamedThing ribonucleoside bisphosphate A nucleoside bisphosphate where sugar of the nucleoside is ribose. FYPO_relaxed.owl CHEBI:71671 biolink:NamedThing aldonate(1-) A carbohydrate acid anion obtained by deprotonation of any aldonic acid. Major structure at pH 7.3 of aldonate compounds. FYPO_relaxed.owl CHEBI:22313 biolink:NamedThing alkaline earth metal atom FYPO_relaxed.owl CHEBI:22314 biolink:NamedThing alkali metal atom FYPO_relaxed.owl CHEBI:33560 biolink:NamedThing p-block element atom Any main group element atom belonging to the p-block of the periodic table. FYPO_relaxed.owl CHEBI:25016 biolink:NamedThing lead atom FYPO_relaxed.owl CHEBI:27007 biolink:NamedThing tin atom FYPO_relaxed.owl CHEBI:27081 biolink:NamedThing transition element atom An element whose atom has an incomplete d sub-shell, or which can give rise to cations with an incomplete d sub-shell. FYPO_relaxed.owl CHEBI:28984 biolink:NamedThing aluminium atom FYPO_relaxed.owl CHEBI:33301 biolink:NamedThing bismuth atom FYPO_relaxed.owl CHEBI:88184 biolink:NamedThing metal allergen Any metal which causes the onset of an allergic reaction. FYPO_relaxed.owl CHEBI:49637 biolink:NamedThing hydrogen atom FYPO_relaxed.owl CHEBI:22323 biolink:NamedThing alkyl group A univalent group -CnH2n+1 derived from an alkane by removal of a hydrogen atom from any carbon atom. FYPO_relaxed.owl CHEBI:33248 biolink:NamedThing hydrocarbyl group A univalent group formed by removing a hydrogen atom from a hydrocarbon. FYPO_relaxed.owl CHEBI:33338 biolink:NamedThing aryl group A group derived from an arene by removal of a hydrogen atom from a ring carbon atom. FYPO_relaxed.owl CHEBI:22331 biolink:NamedThing alkylamines Any amine formally derived from ammonia by replacing one, two or three hydrogen atoms by alkyl groups. FYPO_relaxed.owl CHEBI:59650 biolink:NamedThing amino fatty acid A fatty acid containing at least one amino substituent. FYPO_relaxed.owl CHEBI:22333 biolink:NamedThing alkylating agent Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases. FYPO_relaxed.owl CHEBI:25435 biolink:NamedThing mutagen An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution. FYPO_relaxed.owl CHEBI:24853 biolink:NamedThing intercalator A role played by a chemical agent which exhibits the capability of occupying space between DNA base pairs due to particular properties in size, shape and charge. Intercalation of chemical compounds in DNA helix can result in replication errors (shift, mutation) or DNA damages. FYPO_relaxed.owl CHEBI:22385 biolink:NamedThing alpha-D-glucan FYPO_relaxed.owl CHEBI:37163 biolink:NamedThing glucan A polysaccharide composed of glucose residues. FYPO_relaxed.owl CHEBI:28793 biolink:NamedThing beta-D-glucan FYPO_relaxed.owl CHEBI:22479 biolink:NamedThing amino cyclitol glycoside FYPO_relaxed.owl CHEBI:61689 biolink:NamedThing amino cyclitol Any cyclitol having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups. FYPO_relaxed.owl CHEBI:26605 biolink:NamedThing saponin A glycoside that is a compound containing one or more hydrophilic glycoside moieties combined with a lipophilic triterpenoid or steroid derivative. Found in particular abundance in plant species. FYPO_relaxed.owl CHEBI:35313 biolink:NamedThing hexoside FYPO_relaxed.owl CHEBI:35315 biolink:NamedThing deoxy hexoside FYPO_relaxed.owl CHEBI:47779 biolink:NamedThing aminoglycoside FYPO_relaxed.owl CHEBI:61777 biolink:NamedThing terpene glycoside A terpenoid in which one or more hydroxy functions are glycosylated. FYPO_relaxed.owl CHEBI:22485 biolink:NamedThing glucosamine oligosaccharide FYPO_relaxed.owl CHEBI:22487 biolink:NamedThing alpha-aminoacyl group A univalent carboacyl group formed by loss of OH from the carboxy group of an alpha-amino acid. FYPO_relaxed.owl CHEBI:27207 biolink:NamedThing univalent carboacyl group A univalent carboacyl group is a group formed by loss of OH from the carboxy group of a carboxylic acid. FYPO_relaxed.owl CHEBI:23004 biolink:NamedThing carbamoyl group The univalent carboacyl group formed by loss of -OH from the carboxy group of carbamic acid. FYPO_relaxed.owl CHEBI:42485 biolink:NamedThing formyl group FYPO_relaxed.owl CHEBI:22507 biolink:NamedThing aminoglycoside antibiotic FYPO_relaxed.owl CHEBI:23007 biolink:NamedThing carbohydrate-containing antibiotic Any carbohydrate derivative that exhibits antibiotic activity. FYPO_relaxed.owl CHEBI:81280 biolink:NamedThing Gentamicin X2 FYPO_relaxed.owl CHEBI:26401 biolink:NamedThing purines A class of imidazopyrimidines that consists of purine and its substituted derivatives. FYPO_relaxed.owl CHEBI:26385 biolink:NamedThing purine alkaloid FYPO_relaxed.owl CHEBI:26395 biolink:NamedThing purine nucleotide Any nucleotide that has a purine nucleobase. FYPO_relaxed.owl CHEBI:40036 biolink:NamedThing amitrole A member of the class of triazoles that is 1H-1,2,4-triazole substituted by an amino group at position 3. Used to control annual grasses and aquatic weeds (but not on food crops because it causes cancer in laboratory animals). Its use within the EU was banned from September 2017 on the grounds of potential groundwater contamination and risks to aquatic life; there have also been concerns about its endocrine-disrupting properties. FYPO_relaxed.owl CHEBI:22563 biolink:NamedThing anion A monoatomic or polyatomic species having one or more elementary charges of the electron. FYPO_relaxed.owl CHEBI:24867 biolink:NamedThing monoatomic ion FYPO_relaxed.owl CHEBI:36358 biolink:NamedThing polyatomic ion An ion consisting of more than one atom. FYPO_relaxed.owl CHEBI:36875 biolink:NamedThing radical ion A radical that carries an electric charge. FYPO_relaxed.owl CHEBI:36914 biolink:NamedThing inorganic ion FYPO_relaxed.owl CHEBI:36916 biolink:NamedThing cation A monoatomic or polyatomic species having one or more elementary charges of the proton. FYPO_relaxed.owl CHEBI:33281 biolink:NamedThing antimicrobial agent A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. FYPO_relaxed.owl CHEBI:25605 biolink:NamedThing nucleoside antibiotic FYPO_relaxed.owl CHEBI:33282 biolink:NamedThing antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. FYPO_relaxed.owl CHEBI:35718 biolink:NamedThing antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce. FYPO_relaxed.owl CHEBI:36043 biolink:NamedThing antimicrobial drug A drug used to treat or prevent microbial infections. FYPO_relaxed.owl CHEBI:48219 biolink:NamedThing disinfectant An antimicrobial agent that is applied to non-living objects to destroy harmful microorganisms or to inhibit their activity. FYPO_relaxed.owl CHEBI:65256 biolink:NamedThing antimicrobial food preservative A food preservative which prevents decomposition of food by preventing the growth of fungi or bacteria. In European countries, E-numbers for permitted food preservatives are from E200 to E299, divided into sorbates (E200-209), benzoates (E210-219), sulfites (E220-229), phenols and formates (E230-239), nitrates (E240-259), acetates (E260-269), lactates (E270-279), propionates (E280-289) and others (E290-299). FYPO_relaxed.owl CHEBI:22629 biolink:NamedThing arsenate ion FYPO_relaxed.owl CHEBI:35776 biolink:NamedThing arsenic oxoanion FYPO_relaxed.owl CHEBI:22633 biolink:NamedThing arsenite ion An arsenic oxoanion resulting from the removal of one or more protons from arsenous acid. FYPO_relaxed.owl CHEBI:22632 biolink:NamedThing arsenic molecular entity FYPO_relaxed.owl CHEBI:33302 biolink:NamedThing pnictogen molecular entity A p-block molecular entity containing any pnictogen. FYPO_relaxed.owl CHEBI:26082 biolink:NamedThing phosphorus molecular entity FYPO_relaxed.owl CHEBI:33408 biolink:NamedThing pnictogen oxoacid FYPO_relaxed.owl CHEBI:33459 biolink:NamedThing pnictogen oxoanion FYPO_relaxed.owl CHEBI:33465 biolink:NamedThing elemental pnictogen FYPO_relaxed.owl CHEBI:35881 biolink:NamedThing pnictogen hydride FYPO_relaxed.owl CHEBI:37196 biolink:NamedThing bismuth molecular entity FYPO_relaxed.owl CHEBI:51143 biolink:NamedThing nitrogen molecular entity FYPO_relaxed.owl CHEBI:24834 biolink:NamedThing inorganic anion FYPO_relaxed.owl CHEBI:33443 biolink:NamedThing halogen oxoanion FYPO_relaxed.owl CHEBI:35405 biolink:NamedThing transition element oxoanion FYPO_relaxed.owl CHEBI:62733 biolink:NamedThing aromatic amide An amide in which the amide linkage is bonded directly to an aromatic system. FYPO_relaxed.owl CHEBI:3015 biolink:NamedThing benomyl A member of the class of benzimidazoles that is the methyl ester of [1-(butylcarbamoyl)-1H-benzimidazol-2-yl]carbamic acid. A foliar fungicide used to control a wide range of Ascomycetes and Fungi Imperfecti in a wide range of crops. FYPO_relaxed.owl CHEBI:35735 biolink:NamedThing dicarboxylic acid monoamide FYPO_relaxed.owl CHEBI:22689 biolink:NamedThing bafilomycin A1 The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus. FYPO_relaxed.owl CHEBI:23953 biolink:NamedThing erythromycins FYPO_relaxed.owl CHEBI:25675 biolink:NamedThing oligomycin Any of the 26-membered ring macrolides produced by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases. FYPO_relaxed.owl CHEBI:2682 biolink:NamedThing amphotericin B A macrolide antibiotic used to treat potentially life-threatening fungal infections. FYPO_relaxed.owl CHEBI:48080 biolink:NamedThing brefeldin A A metabolite from Penicillium brefeldianum that exhibits a wide range of antibiotic activity. FYPO_relaxed.owl CHEBI:46942 biolink:NamedThing oxanes Any organic heteromonocyclic compoundthat is oxane or its substituted derivatives. FYPO_relaxed.owl CHEBI:59780 biolink:NamedThing cyclic hemiketal A hemiacetal having the structure R2C(OH)OR (R =/= H), derived from a ketone by formal addition of an alcohol to the carbonyl group. The term 'cyclic hemiketals', once abandoned by IUPAC, has been reinstated as a subclass of hemiacetals. FYPO_relaxed.owl CHEBI:22702 biolink:NamedThing benzamides FYPO_relaxed.owl CHEBI:33836 biolink:NamedThing benzenoid aromatic compound FYPO_relaxed.owl CHEBI:51269 biolink:NamedThing acenes Polycyclic aromatic hydrocarbons consisting of fused benzene rings in a rectilinear arrangement and their substitution derivatives. FYPO_relaxed.owl CHEBI:26518 biolink:NamedThing quinuclidines FYPO_relaxed.owl CHEBI:35570 biolink:NamedThing mancude organic heterobicyclic parent FYPO_relaxed.owl CHEBI:38297 biolink:NamedThing thiabicycloalkane FYPO_relaxed.owl CHEBI:38932 biolink:NamedThing pyridopyrimidine Any organic heterobicyclic compound consisting of a pyridine ring ortho-fused at any position to a pyrimidine ring. FYPO_relaxed.owl CHEBI:46733 biolink:NamedThing oxabicycloalkane FYPO_relaxed.owl CHEBI:33859 biolink:NamedThing aromatic carboxylic acid Any carboxylic acid in which the carboxy group is directly bonded to an aromatic ring. FYPO_relaxed.owl CHEBI:38104 biolink:NamedThing oxacycle Any organic heterocyclic compound containing at least one ring oxygen atom. FYPO_relaxed.owl CHEBI:24129 biolink:NamedThing furans Compounds containing at least one furan ring. FYPO_relaxed.owl CHEBI:26407 biolink:NamedThing pyrans FYPO_relaxed.owl CHEBI:26912 biolink:NamedThing oxolanes Any oxacycle having an oxolane (tetrahydrofuran) skeleton. FYPO_relaxed.owl CHEBI:35790 biolink:NamedThing oxazole An azole based on a five-membered heterocyclic aromatic skeleton containing one N and one O atom. FYPO_relaxed.owl CHEBI:37407 biolink:NamedThing cyclic ether Any ether in which the oxygen atom forms part of a ring. FYPO_relaxed.owl CHEBI:39430 biolink:NamedThing dioxolane FYPO_relaxed.owl CHEBI:59779 biolink:NamedThing cyclic ketal A ketal in the molecule of which the ketal carbon and one or both oxygen atoms thereon are members of a ring. FYPO_relaxed.owl CHEBI:38180 biolink:NamedThing polycyclic heteroarene FYPO_relaxed.owl CHEBI:36421 biolink:NamedThing phenanthridine An azaarene that is the 9-aza derivative of phenanthrene. The parent of the class of phenanthridines. FYPO_relaxed.owl CHEBI:41275 biolink:NamedThing 1H-benzimidazole The 1H-tautomer of benzimidazole. FYPO_relaxed.owl CHEBI:52362 biolink:NamedThing ortho-fused heteroarene An ortho-fused compound in which at least one of the rings contains at least one heteroatom. FYPO_relaxed.owl CHEBI:22743 biolink:NamedThing benzyl alcohols Compounds containing a phenylmethanol skeleton. FYPO_relaxed.owl CHEBI:22744 biolink:NamedThing benzyl group FYPO_relaxed.owl CHEBI:33452 biolink:NamedThing benzylic group Arylmethyl groups and derivatives formed by substitution: ArCR2-. FYPO_relaxed.owl CHEBI:50325 biolink:NamedThing proteinogenic amino-acid side-chain group A univalent organyl group obtained by cleaving the bond from C-2 to the side chain of a proteinogenic amino-acid. FYPO_relaxed.owl CHEBI:24712 biolink:NamedThing hydroxymethyl group FYPO_relaxed.owl CHEBI:30353 biolink:NamedThing isopropyl group FYPO_relaxed.owl CHEBI:30356 biolink:NamedThing isobutyl group FYPO_relaxed.owl CHEBI:41402 biolink:NamedThing carboxymethyl group FYPO_relaxed.owl CHEBI:45557 biolink:NamedThing sec-butyl group FYPO_relaxed.owl CHEBI:50326 biolink:NamedThing sulfanylmethyl group FYPO_relaxed.owl CHEBI:50329 biolink:NamedThing 2-carboxyethyl group FYPO_relaxed.owl CHEBI:50330 biolink:NamedThing 2-amino-2-oxoethyl group FYPO_relaxed.owl CHEBI:50331 biolink:NamedThing 3-amino-3-oxopropyl group FYPO_relaxed.owl CHEBI:50336 biolink:NamedThing 4-hydroxybenzyl group FYPO_relaxed.owl CHEBI:50337 biolink:NamedThing 1H-indol-3-ylmethyl group FYPO_relaxed.owl CHEBI:50338 biolink:NamedThing 1H-imidazol-4-ylmethyl group FYPO_relaxed.owl CHEBI:50339 biolink:NamedThing 4-aminobutyl group FYPO_relaxed.owl CHEBI:50340 biolink:NamedThing 3-carbamimidamidopropyl group FYPO_relaxed.owl CHEBI:50341 biolink:NamedThing 1-hydroxyethyl group FYPO_relaxed.owl CHEBI:22798 biolink:NamedThing beta-D-glucoside Any D-glucoside in which the anomeric centre has beta-configuration. FYPO_relaxed.owl CHEBI:35436 biolink:NamedThing D-glucoside Any glucoside in which the glycoside group is derived from D-glucose. FYPO_relaxed.owl CHEBI:60980 biolink:NamedThing beta-glucoside A glucoside in which the anomeric carbon of the glycosidic bond is in a beta configuration FYPO_relaxed.owl CHEBI:35284 biolink:NamedThing ammonium betaine Any neutral molecule having charge-separated forms with a quaternary ammonium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom. FYPO_relaxed.owl CHEBI:64482 biolink:NamedThing phosphatidylcholine A glycerophosphocholine that is glycero-3-phosphocholine bearing two acyl substituents at positions 1 and 2. FYPO_relaxed.owl CHEBI:79070 biolink:NamedThing hercynylselenocysteine A L-histidine derivative which is an intermediate in the synthesis of selenoneine, a compound found in certain fungi and mycobacteria. FYPO_relaxed.owl CHEBI:22902 biolink:NamedThing bisphosphoglyceric acid A glyceric acid phosphate in which both of the hydroxy groups have been phosphorylated. FYPO_relaxed.owl CHEBI:24346 biolink:NamedThing phosphoglyceric acid An aldonic acid phosphate where the aldonic acid component is glyceric acid. FYPO_relaxed.owl CHEBI:22907 biolink:NamedThing bleomycin A glycopeptide produced by the bacterium Streptomyces verticillus. The term, 'bleomycin' refers to a family of structurally related compounds. When used as an anti-cancer agent, the chemotherapeutical forms are primarily bleomycin A2 and B2. FYPO_relaxed.owl CHEBI:23089 biolink:NamedThing chelate-forming peptide FYPO_relaxed.owl CHEBI:75046 biolink:NamedThing phleomycin D1 A glycopeptide originally isolated from the bacterium Streptomyces verticillus which contains a (4'R)-4',5'-dihydro-2,4'-bi-1,3-thiazole-2',4-diyl moiety with a a 4-guanidylbutylaminocarbonyl group attached to the 4-position of the terminal thiazole ring. Like all phleomycins, phleomycin D1 can form complexes with redox-active metals such as Co, Cu, and Fe. FYPO_relaxed.owl CHEBI:22916 biolink:NamedThing boron molecular entity FYPO_relaxed.owl CHEBI:33581 biolink:NamedThing boron group molecular entity FYPO_relaxed.owl CHEBI:33620 biolink:NamedThing aluminium molecular entity FYPO_relaxed.owl CHEBI:22917 biolink:NamedThing phytogenic insecticide An insecticide compound naturally occurring in plants. FYPO_relaxed.owl CHEBI:71692 biolink:NamedThing insect repellent An insecticide that acts as a repellent to insects. FYPO_relaxed.owl CHEBI:22918 biolink:NamedThing branched-chain amino acid Any amino acid in which the parent hydrocarbon chain has one or more alkyl substituents FYPO_relaxed.owl CHEBI:35987 biolink:NamedThing diamino acid Any amino acid carrying two amino groups. FYPO_relaxed.owl CHEBI:38108 biolink:NamedThing azetidine-2-carboxylic acid An azetidinecarboxylic acid that is azetidine substituted by a carboxy group at position 2. It is a plant non-protein amino acid. FYPO_relaxed.owl CHEBI:60892 biolink:NamedThing polyamino carboxylic acid An amino acid containing one or more nitrogen atoms connected through carbon atoms to one or more carboxy groups. FYPO_relaxed.owl CHEBI:83820 biolink:NamedThing non-proteinogenic amino acid Any amino-acid that is not naturally encoded in the genetic code of any organism. FYPO_relaxed.owl CHEBI:22925 biolink:NamedThing bromide salt FYPO_relaxed.owl CHEBI:22928 biolink:NamedThing bromine molecular entity FYPO_relaxed.owl CHEBI:37141 biolink:NamedThing organobromine compound A compound containing at least one carbon-bromine bond. FYPO_relaxed.owl CHEBI:24060 biolink:NamedThing fluoride salt FYPO_relaxed.owl CHEBI:22927 biolink:NamedThing bromine atom FYPO_relaxed.owl CHEBI:24473 biolink:NamedThing halogen FYPO_relaxed.owl CHEBI:23116 biolink:NamedThing chlorine atom FYPO_relaxed.owl CHEBI:24061 biolink:NamedThing fluorine atom FYPO_relaxed.owl CHEBI:24859 biolink:NamedThing iodine atom Chemical element with atomic number 53. FYPO_relaxed.owl CHEBI:24471 biolink:NamedThing halogen molecular entity FYPO_relaxed.owl CHEBI:24062 biolink:NamedThing fluorine molecular entity FYPO_relaxed.owl CHEBI:24860 biolink:NamedThing iodine molecular entity FYPO_relaxed.owl CHEBI:33425 biolink:NamedThing halogen oxoacid FYPO_relaxed.owl CHEBI:37749 biolink:NamedThing halogen oxide FYPO_relaxed.owl CHEBI:22977 biolink:NamedThing cadmium atom FYPO_relaxed.owl CHEBI:33340 biolink:NamedThing zinc group element atom FYPO_relaxed.owl CHEBI:25195 biolink:NamedThing mercury atom FYPO_relaxed.owl CHEBI:27363 biolink:NamedThing zinc atom FYPO_relaxed.owl CHEBI:22978 biolink:NamedThing cadmium molecular entity FYPO_relaxed.owl CHEBI:33673 biolink:NamedThing zinc group molecular entity FYPO_relaxed.owl CHEBI:25196 biolink:NamedThing mercury molecular entity FYPO_relaxed.owl CHEBI:27364 biolink:NamedThing zinc molecular entity FYPO_relaxed.owl CHEBI:22984 biolink:NamedThing calcium atom FYPO_relaxed.owl CHEBI:25107 biolink:NamedThing magnesium atom FYPO_relaxed.owl CHEBI:22985 biolink:NamedThing calcium molecular entity FYPO_relaxed.owl CHEBI:33299 biolink:NamedThing alkaline earth molecular entity An alkaline earth molecular entity is a molecular entity containing one or more atoms of an alkaline earth metal. FYPO_relaxed.owl CHEBI:25108 biolink:NamedThing magnesium molecular entity FYPO_relaxed.owl CHEBI:33513 biolink:NamedThing alkaline earth cation FYPO_relaxed.owl CHEBI:35217 biolink:NamedThing alkaline earth coordination entity FYPO_relaxed.owl CHEBI:36364 biolink:NamedThing alkaline earth salt FYPO_relaxed.owl CHEBI:22986 biolink:NamedThing calcium ionophore FYPO_relaxed.owl CHEBI:24869 biolink:NamedThing ionophore A compound which can carry specific ions through membranes of cells or organelles. FYPO_relaxed.owl CHEBI:24874 biolink:NamedThing iron ionophore Any ionophore capable of transportation of iron ions across membranes. FYPO_relaxed.owl CHEBI:88227 biolink:NamedThing potassium ionophore Any ionophore capable of transportation of potassium ions across membranes. FYPO_relaxed.owl CHEBI:23003 biolink:NamedThing carbamate ester Any ester of carbamic acid or its N-substituted derivatives. FYPO_relaxed.owl CHEBI:23990 biolink:NamedThing ethyl ester Any carboxylic ester resulting from the formal condensation of the carboxy group of a carboxylic acid with ethanol. FYPO_relaxed.owl CHEBI:25248 biolink:NamedThing methyl ester Any carboxylic ester resulting from the formal condensation of a carboxy group with methanol. FYPO_relaxed.owl CHEBI:35915 biolink:NamedThing sterol ester A steroid ester obtained by formal condensation of the carboxy group of any carboxylic acid with the 3-hydroxy group of a sterol. FYPO_relaxed.owl CHEBI:36244 biolink:NamedThing dicarboxylic acid monoester A monoester of a dicarboxylic acid. FYPO_relaxed.owl CHEBI:47622 biolink:NamedThing acetate ester Any carboxylic ester where the carboxylic acid component is acetic acid. FYPO_relaxed.owl CHEBI:51737 biolink:NamedThing alpha,beta-unsaturated carboxylic ester A carboxylic ester of general formula R(1)R(2)C=CR(3)-C(=O)OR(4) (R(4) =/= H) or R(1)C#C-C(=O)OR(2) (R(2) =/= H) in which the ester C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position. FYPO_relaxed.owl CHEBI:28963 biolink:NamedThing amino sugar Any sugar having one or more alcoholic hydroxy groups replaced by substituted or unsubstituted amino groups. FYPO_relaxed.owl CHEBI:35241 biolink:NamedThing nucleotide-carbohydrate FYPO_relaxed.owl CHEBI:63353 biolink:NamedThing disaccharide derivative A carbohydrate derivative that is formally obtained from a disaccharide. FYPO_relaxed.owl CHEBI:63367 biolink:NamedThing monosaccharide derivative A carbohydrate derivative that is formally obtained from a monosaccharide. FYPO_relaxed.owl CHEBI:63436 biolink:NamedThing carbohydrate acid derivative A carbohydrate derivative that is formally obtained from a carbohydrate acid. FYPO_relaxed.owl CHEBI:23019 biolink:NamedThing carbonyl group FYPO_relaxed.owl CHEBI:51422 biolink:NamedThing organodiyl group Any organic substituent group, regardless of functional type, having two free valences at carbon atom(s). FYPO_relaxed.owl CHEBI:30256 biolink:NamedThing thiocarbonyl group FYPO_relaxed.owl CHEBI:23079 biolink:NamedThing cerebroside Any member of a group of glycosphingolipids, also known as monoglycosylceramides, which are important components in animal muscle and nerve cell membranes. FYPO_relaxed.owl CHEBI:62941 biolink:NamedThing glycosylceramide A ceramide compound formed by the replacement of the glycosidic hydroxy group of a cyclic form of a monosaccharide (or derivative) by a ceramide group. FYPO_relaxed.owl CHEBI:84403 biolink:NamedThing phytoceramides A phytoceramide is a ceramide where the sphingoid base is hydroxylated at position 4. These backbone bases can be 14 to 20 carbons long, either straight chain or branched. The N-linked fatty acids are typically saturated or monounsaturated with chain lengths from 14 to 26 carbon atoms; the presence of a hydroxyl group on carbon 2 is fairly common. In the illustrated generalised structure, R1 = OH, OX (where X = acyl, glycosyl, phosphate, phosphonate, etc.), or H. FYPO_relaxed.owl CHEBI:25513 biolink:NamedThing neutral glycosphingolipid Any glycosphingolipid containing unsubstituted glycosyl moieties. FYPO_relaxed.owl CHEBI:61739 biolink:NamedThing aureobasidin A A cyclodepsipeptide antibiotic, which is isolated from the filamentous fungus Aureobasidium pullulans R106 and is toxic to yeast at low concentrations (0.1-0.5 ug/ml). FYPO_relaxed.owl CHEBI:23213 biolink:NamedThing choline ester FYPO_relaxed.owl CHEBI:35701 biolink:NamedThing ester A compound formally derived from an oxoacid RkE(=O)l(OH)m (l > 0) and an alcohol, phenol, heteroarenol, or enol by linking with formal loss of water from an acidic hydroxy group of the former and a hydroxy group of the latter. FYPO_relaxed.owl CHEBI:26819 biolink:NamedThing sulfuric ester An ester of an alcohol and sulfuric acid. FYPO_relaxed.owl CHEBI:62732 biolink:NamedThing aromatic ester An ester where the ester linkage is bonded directly to an aromatic system. FYPO_relaxed.owl CHEBI:83347 biolink:NamedThing organosulfonic ester An ester resulting from the formal condensation of the hydroxy group of an alcohol, phenol, heteroarenol, or enol with an organosulfonic acid. FYPO_relaxed.owl CHEBI:46020 biolink:NamedThing tetramethylammonium The simplest quaternary ammonium cation, comprising a central nitrogen linked to four methyl groups. FYPO_relaxed.owl CHEBI:49183 biolink:NamedThing phosphatidylcholine(1+) A glycerophosphocholine compound having O-acyl substituents at both the 1- and 2-positions of the glycerol. It is a major constituent of cell membranes. FYPO_relaxed.owl CHEBI:67049 biolink:NamedThing N(alpha),N(alpha),N(alpha)-trimethyl-L-histidinium(1+) A quaternary ammonium ion obtained by the protonation of the carboxy function of N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine. FYPO_relaxed.owl CHEBI:23230 biolink:NamedThing chromanes FYPO_relaxed.owl CHEBI:38443 biolink:NamedThing 1-benzopyran FYPO_relaxed.owl CHEBI:23232 biolink:NamedThing chromenes FYPO_relaxed.owl CHEBI:23237 biolink:NamedThing chromium molecular entity FYPO_relaxed.owl CHEBI:33741 biolink:NamedThing chromium group molecular entity FYPO_relaxed.owl CHEBI:25370 biolink:NamedThing molybdenum molecular entity FYPO_relaxed.owl CHEBI:23243 biolink:NamedThing cineole FYPO_relaxed.owl CHEBI:26876 biolink:NamedThing terpineol A family of monoterpenols that have a p-menthane skeleton containing one double bond and bearing a single hydroxy substituent. FYPO_relaxed.owl CHEBI:23336 biolink:NamedThing cobalt cation FYPO_relaxed.owl CHEBI:33515 biolink:NamedThing transition element cation FYPO_relaxed.owl CHEBI:23378 biolink:NamedThing copper cation FYPO_relaxed.owl CHEBI:24875 biolink:NamedThing iron cation FYPO_relaxed.owl CHEBI:25155 biolink:NamedThing manganese cation FYPO_relaxed.owl CHEBI:25197 biolink:NamedThing mercury cation FYPO_relaxed.owl CHEBI:25516 biolink:NamedThing nickel cation FYPO_relaxed.owl CHEBI:33516 biolink:NamedThing chromium cation FYPO_relaxed.owl CHEBI:37239 biolink:NamedThing molybdenum cation FYPO_relaxed.owl CHEBI:60253 biolink:NamedThing silver cation FYPO_relaxed.owl CHEBI:63063 biolink:NamedThing cadmium cation A transition element cation where the metal is specifed as cadmium. FYPO_relaxed.owl CHEBI:23354 biolink:NamedThing coenzyme A low-molecular-weight, non-protein organic compound participating in enzymatic reactions as dissociable acceptor or donor of chemical groups or electrons. FYPO_relaxed.owl CHEBI:26348 biolink:NamedThing prosthetic group A tightly bound, specific nonpolypeptide unit in a protein determining and involved in its biological activity. FYPO_relaxed.owl CHEBI:26672 biolink:NamedThing siderophore Any of low-molecular-mass iron(III)-chelating compounds produced by microorganisms for the purpose of the transport and sequestration of iron. FYPO_relaxed.owl CHEBI:23366 biolink:NamedThing compatible osmolytes FYPO_relaxed.owl CHEBI:25728 biolink:NamedThing osmolyte A solute used by a cell under water stress to maintain cell volume. FYPO_relaxed.owl CHEBI:24431 biolink:NamedThing chemical entity A chemical entity is a physical entity of interest in chemistry including molecular entities, parts thereof, and chemical substances. FYPO_relaxed.owl CHEBI:24433 biolink:NamedThing group A defined linked collection of atoms or a single atom within a molecular entity. FYPO_relaxed.owl CHEBI:59999 biolink:NamedThing chemical substance A chemical substance is a portion of matter of constant composition, composed of molecular entities of the same type or of different types. FYPO_relaxed.owl CHEBI:23377 biolink:NamedThing copper molecular entity FYPO_relaxed.owl CHEBI:33745 biolink:NamedThing copper group molecular entity FYPO_relaxed.owl CHEBI:33964 biolink:NamedThing silver molecular entity FYPO_relaxed.owl CHEBI:37404 biolink:NamedThing elemental copper FYPO_relaxed.owl CHEBI:23403 biolink:NamedThing coumarins FYPO_relaxed.owl CHEBI:26004 biolink:NamedThing phenylpropanoid Any organic aromatic compound with a structure based on a phenylpropane skeleton. The class includes naturally occurring phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules as well as their semi-synthetic and synthetic analogues. Phenylpropanoids are also precursors of lignin. FYPO_relaxed.owl CHEBI:25036 biolink:NamedThing lignan Any phenylpropanoid derived from phenylalanine via dimerization of substituted cinnamic alcohols, known as monolignols, to a dibenzylbutane skeleton. Note that while individual members of the class have names ending ...lignane, ...lignene, ...lignadiene, etc., the class names lignan, neolignan, etc., do not end with an "e". FYPO_relaxed.owl CHEBI:38445 biolink:NamedThing chromenone FYPO_relaxed.owl CHEBI:23443 biolink:NamedThing cyclic amide FYPO_relaxed.owl CHEBI:32988 biolink:NamedThing amide An amide is a derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. FYPO_relaxed.owl CHEBI:33256 biolink:NamedThing primary amide A derivative of an oxoacid RkE(=O)l(OH)m (l =/= 0) in which an acidic hydroxy group has been replaced by an amino or substituted amino group. FYPO_relaxed.owl CHEBI:33257 biolink:NamedThing secondary amide A derivative of two oxoacids RkE(=O)l(OH)m (l =/= 0) in which two acyl groups are attached to the amino or substituted amino group. FYPO_relaxed.owl CHEBI:46844 biolink:NamedThing N-acylpiperazine FYPO_relaxed.owl CHEBI:23446 biolink:NamedThing cyclic monoterpene ketone A cyclic terpene ketone in which the terpene specified is monoterpene. FYPO_relaxed.owl CHEBI:25408 biolink:NamedThing monoterpene ketone A terpene ketone derived from a monoterpene. FYPO_relaxed.owl CHEBI:36130 biolink:NamedThing cyclic terpene ketone An alicyclic ketone in which the carbocyclic ring structure forms part of a terpene skeleton. FYPO_relaxed.owl CHEBI:26441 biolink:NamedThing pyrimidine nucleotide FYPO_relaxed.owl CHEBI:47885 biolink:NamedThing dinucleotide FYPO_relaxed.owl CHEBI:23482 biolink:NamedThing cyclohexanones Any alicyclic ketone based on a cyclohexane skeleton and its substituted derivatives thereof. FYPO_relaxed.owl CHEBI:39446 biolink:NamedThing pyrimidine ribonucleosides FYPO_relaxed.owl CHEBI:27242 biolink:NamedThing uridines FYPO_relaxed.owl CHEBI:23528 biolink:NamedThing cytochalasin FYPO_relaxed.owl CHEBI:75946 biolink:NamedThing cytochalasan alkaloid Any alkaloid characterized by the presence of an isoindole nucleus fused to a macrocyclic ring. FYPO_relaxed.owl CHEBI:24897 biolink:NamedThing isoindoles FYPO_relaxed.owl CHEBI:61297 biolink:NamedThing adenyl deoxyribonucleotide A purine 2'-deoxyribonucleotide where the purine is adenine. FYPO_relaxed.owl CHEBI:25900 biolink:NamedThing aldopentose phosphate FYPO_relaxed.owl CHEBI:23666 biolink:NamedThing diamine Any polyamine that contains two amino groups. FYPO_relaxed.owl CHEBI:23677 biolink:NamedThing diazole An azole that is either one of a pair of heterocyclic organic compounds comprising three carbon atoms and two nitrogen atoms arranged in a ring. FYPO_relaxed.owl CHEBI:26455 biolink:NamedThing pyrroles An azole that includes only one N atom and no other heteroatom as a part of the aromatic skeleton. FYPO_relaxed.owl CHEBI:35689 biolink:NamedThing tetrazoles An azole in which the five-membered heterocyclic aromatic skeleton contains four N atoms and one C atom. FYPO_relaxed.owl CHEBI:35727 biolink:NamedThing triazoles An azole in which the five-membered heterocyclic aromatic skeleton contains three N atoms and two C atoms. FYPO_relaxed.owl CHEBI:48901 biolink:NamedThing thiazoles An azole in which the five-membered heterocyclic aromatic skeleton contains a N atom and one S atom. FYPO_relaxed.owl CHEBI:86323 biolink:NamedThing conazole antifungal agent A compound that has a structure that is related to miconazole, contains an azole (imidazole or triazole) moiety, and has significant systemic antifungal properties. They inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. FYPO_relaxed.owl CHEBI:26888 biolink:NamedThing tetrachlorobenzene Any member of the class of chlorobenzenes carrying four chloro groups at unspecified positions. FYPO_relaxed.owl CHEBI:83403 biolink:NamedThing monochlorobenzenes Any member of the class of chlorobenzenes containing a mono- or poly-substituted benzene ring in which only one substituent is chlorine. FYPO_relaxed.owl CHEBI:23778 biolink:NamedThing dihydroxybenzoic acid Any member of the class of hydroxybenzoic acids carrying two phenolic hydroxy groups on the benzene ring and its derivatives. FYPO_relaxed.owl CHEBI:25389 biolink:NamedThing monohydroxybenzoic acid Any hydroxybenzoic acid having a single phenolic hydroxy substituent on the benzene ring. FYPO_relaxed.owl CHEBI:23872 biolink:NamedThing dodecyl sulfate FYPO_relaxed.owl CHEBI:83414 biolink:NamedThing alkyl sulfate(1-) An organosulfate oxoanion obtained by deprotonation of the sulfo group of any alkyl sulfate; major species at pH 7.3. FYPO_relaxed.owl CHEBI:33295 biolink:NamedThing diagnostic agent A substance administered to aid diagnosis of a disease. FYPO_relaxed.owl CHEBI:60809 biolink:NamedThing adjuvant Any pharmacological or immunological agent that modifies the effect of other agents such as drugs or vaccines while having few if any direct effects when given by itself. FYPO_relaxed.owl CHEBI:23905 biolink:NamedThing monoatomic anion FYPO_relaxed.owl CHEBI:33273 biolink:NamedThing polyatomic anion An anion consisting of more than one atom. FYPO_relaxed.owl CHEBI:36830 biolink:NamedThing monoanion FYPO_relaxed.owl CHEBI:36873 biolink:NamedThing radical anion FYPO_relaxed.owl CHEBI:23906 biolink:NamedThing monoatomic cation FYPO_relaxed.owl CHEBI:27365 biolink:NamedThing zinc ion FYPO_relaxed.owl CHEBI:33702 biolink:NamedThing polyatomic cation A cation consisting of more than one atom. FYPO_relaxed.owl CHEBI:36915 biolink:NamedThing inorganic cation FYPO_relaxed.owl CHEBI:23994 biolink:NamedThing ethyl methanesulfonate A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with ethanol. FYPO_relaxed.owl CHEBI:25223 biolink:NamedThing methanesulfonate ester An organosulfonic ester resulting from the formal condensation of methanesulfonic acid with the hydroxy group of an alcohol, phenol, heteroarenol, or enol. FYPO_relaxed.owl CHEBI:25255 biolink:NamedThing methyl methanesulfonate A methanesulfonate ester resulting from the formal condensation of methanesulfonic acid with methanol. FYPO_relaxed.owl CHEBI:24018 biolink:NamedThing farnesyl phosphate FYPO_relaxed.owl CHEBI:24020 biolink:NamedThing fat-soluble vitamin (role) Any vitamin that dissolves in fats and are stored in body tissues. Unlike the water-soluble vitamins, they are stored in the body for long periods of time and generally pose a greater risk for toxicity when consumed in excess. FYPO_relaxed.owl CHEBI:27314 biolink:NamedThing water-soluble vitamin (role) Any vitamin that dissolves in water and readily absorbed into tissues for immediate use. Unlike the fat-soluble vitamins, they are not stored in the body and need to be replenished regularly in the diet and will rarely accumulate to toxic levels since they are quickly excreted from the body via urine. FYPO_relaxed.owl CHEBI:24028 biolink:NamedThing iron(3+) chelator FYPO_relaxed.owl CHEBI:24688 biolink:NamedThing monohydroxycinnamic acid FYPO_relaxed.owl CHEBI:35618 biolink:NamedThing aromatic ether Any ether in which the oxygen is attached to at least one aryl substituent. FYPO_relaxed.owl CHEBI:3962 biolink:NamedThing curcumin A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. FYPO_relaxed.owl CHEBI:37143 biolink:NamedThing organofluorine compound An organofluorine compound is a compound containing at least one carbon-fluorine bond. FYPO_relaxed.owl CHEBI:24068 biolink:NamedThing fluoroamino acid An organofluorine compound that consists of an amino acid substituted by a fluoro group. FYPO_relaxed.owl CHEBI:24470 biolink:NamedThing haloamino acid Any non-proteinogenic amino acid carrying at least one halo group. FYPO_relaxed.owl CHEBI:45951 biolink:NamedThing trifluoperazine A member of the class of phenothiazines that is phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position. FYPO_relaxed.owl CHEBI:5123 biolink:NamedThing fluphenazine A member of the class of phenothiazines that is 10H-phenothiazine having a trifluoromethyl subsitituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position. FYPO_relaxed.owl CHEBI:64089 biolink:NamedThing vanoxerine An N-alkylpiperazine that consists of piperazine bearing 2-bis(4-fluorophenyl)methoxy]ethyl and 3-phenylpropyl groups at positions 1 and 4 respectively. Potent, competitive inhibitor of dopamine uptake (Ki = 1 nM for inhibition of striatal dopamine uptake). Has > 100-fold lower affinity for the noradrenalin and 5-HT uptake carriers. Also a potent sigma ligand (IC50 = 48 nM). Centrally active following systemic administration. FYPO_relaxed.owl CHEBI:84327 biolink:NamedThing torin 1 A member of the class of pyridoquinolines that is 9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2-one bearing an additional 4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl substituent at position 1. It is a potent inhibitor of mTOR and exhibits anti-cancer properties. FYPO_relaxed.owl CHEBI:83734 biolink:NamedThing sterol demethylation inhibitor A sterol biosynthesis inhibitor that acts by inhibiting the C14 demethylation step within fungal steroid biosynthesis. FYPO_relaxed.owl CHEBI:86327 biolink:NamedThing antifungal drug Any antifungal agent used to prevent or treat fungal infections in humans or animals. FYPO_relaxed.owl CHEBI:25693 biolink:NamedThing organic heteromonocyclic compound FYPO_relaxed.owl CHEBI:35555 biolink:NamedThing mancude organic heteromonocyclic parent FYPO_relaxed.owl CHEBI:36389 biolink:NamedThing saturated organic heteromonocyclic parent FYPO_relaxed.owl CHEBI:38102 biolink:NamedThing triazines Compounds based on a triazine skeleton. FYPO_relaxed.owl CHEBI:33804 biolink:NamedThing gluconates FYPO_relaxed.owl CHEBI:24266 biolink:NamedThing gluconic acid FYPO_relaxed.owl CHEBI:33752 biolink:NamedThing hexonic acid Any aldonic acid formed by oxidising the aldehyde group of an aldohexose to a carboxylic acid group. FYPO_relaxed.owl CHEBI:25174 biolink:NamedThing mannooligosaccharide An oligosaccharide comprised of mannose residues. FYPO_relaxed.owl CHEBI:36233 biolink:NamedThing disaccharide A compound in which two monosaccharides are joined by a glycosidic bond. FYPO_relaxed.owl CHEBI:24278 biolink:NamedThing glucoside FYPO_relaxed.owl CHEBI:70813 biolink:NamedThing glutamine derivative A glutamic acid derivative resulting from reaction of glutamine acid at the amino group, the carboxy group, or the side-chain carboxamide, or from the replacement of any hydrogen by a heteroatom. The definition normally excludes peptides containing glutamine residues. FYPO_relaxed.owl CHEBI:24319 biolink:NamedThing EC 6.3.1.2 (glutamate--ammonia ligase) inhibitor An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of glutamate--ammonia ligase (EC 6.3.1.2). FYPO_relaxed.owl CHEBI:76823 biolink:NamedThing EC 6.3.1.* (acid-ammonia/amine ligase) inhibitor An EC 6.3.* (C-N bond-forming ligase) inhibitor that interferes with the action of any acid-ammonia (or amine) ligase (EC 6.3.1.*). FYPO_relaxed.owl CHEBI:36963 biolink:NamedThing organooxygen compound An organochalcogen compound containing at least one carbon-oxygen bond. FYPO_relaxed.owl CHEBI:25698 biolink:NamedThing ether An organooxygen compound with formula ROR, where R is not hydrogen. FYPO_relaxed.owl CHEBI:26188 biolink:NamedThing polyketide Natural and synthetic compounds containing alternating carbonyl and methylene groups ('beta-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations, etc. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides. FYPO_relaxed.owl CHEBI:35605 biolink:NamedThing carbon oxoacid FYPO_relaxed.owl CHEBI:35924 biolink:NamedThing peroxol Monosubstitution products of hydrogen peroxide HOOH, having the skeleton ROOH, in which R is any organyl group. FYPO_relaxed.owl CHEBI:48589 biolink:NamedThing piperidones FYPO_relaxed.owl CHEBI:59769 biolink:NamedThing acetal An organooxygen compound having the structure RR'C(OR'')(OR''') (R'', R''' =/= H). Mixed acetals have R'' and R''' groups which differ. FYPO_relaxed.owl CHEBI:87631 biolink:NamedThing statin Any organooxygen compound whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties. FYPO_relaxed.owl CHEBI:24347 biolink:NamedThing glycerates FYPO_relaxed.owl CHEBI:33763 biolink:NamedThing trionate FYPO_relaxed.owl CHEBI:24397 biolink:NamedThing glycophospholipid Any phospholipid that contain both phosphate and carbohydrate as integral structural components. FYPO_relaxed.owl CHEBI:37841 biolink:NamedThing isoprenoid phosphate FYPO_relaxed.owl CHEBI:33563 biolink:NamedThing glycolipid Any member of class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar part acylated by one or more fatty acids and the glycerol part may be absent. FYPO_relaxed.owl CHEBI:5254 biolink:NamedThing galactolipid A glycolipid and which the glyco component is specified as galactosyl. FYPO_relaxed.owl CHEBI:24432 biolink:NamedThing biological role A role played by the molecular entity or part thereof within a biological context. FYPO_relaxed.owl CHEBI:50906 biolink:NamedThing role A role is particular behaviour which a material entity may exhibit. FYPO_relaxed.owl CHEBI:33304 biolink:NamedThing chalcogen molecular entity Any p-block molecular entity containing a chalcogen. FYPO_relaxed.owl CHEBI:33582 biolink:NamedThing carbon group molecular entity FYPO_relaxed.owl CHEBI:25555 biolink:NamedThing nitrogen atom FYPO_relaxed.owl CHEBI:25805 biolink:NamedThing oxygen atom FYPO_relaxed.owl CHEBI:26833 biolink:NamedThing sulfur atom FYPO_relaxed.owl CHEBI:27560 biolink:NamedThing boron atom FYPO_relaxed.owl CHEBI:27568 biolink:NamedThing selenium atom FYPO_relaxed.owl CHEBI:27573 biolink:NamedThing silicon atom FYPO_relaxed.owl CHEBI:27594 biolink:NamedThing carbon atom FYPO_relaxed.owl CHEBI:28659 biolink:NamedThing phosphorus atom FYPO_relaxed.owl CHEBI:33300 biolink:NamedThing pnictogen Any p-block element atom that is in group 15 of the periodic table: nitrogen, phosphorus, arsenic, antimony and bismuth. FYPO_relaxed.owl CHEBI:33303 biolink:NamedThing chalcogen Any p-block element belonging to the group 16 family of the periodic table. FYPO_relaxed.owl CHEBI:33306 biolink:NamedThing carbon group element atom FYPO_relaxed.owl CHEBI:33317 biolink:NamedThing boron group element atom FYPO_relaxed.owl CHEBI:2450 biolink:NamedThing aculeacin A A lipopeptide that is isolated from Aspergillus aculeatus and exhibits antifungal activity. FYPO_relaxed.owl CHEBI:24533 biolink:NamedThing heterodetic cyclic peptide A heterodetic cyclic peptide is a peptide consisting only of amino-acid residues, but in which the linkages forming the ring are not solely peptide bonds; one or more is an isopeptide, disulfide, ester, or other bond. FYPO_relaxed.owl CHEBI:59062 biolink:NamedThing polymyxin Polymyxins are antibiotics with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. Polymyxins are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria. FYPO_relaxed.owl CHEBI:24531 biolink:NamedThing heterocyclic antibiotic FYPO_relaxed.owl CHEBI:33833 biolink:NamedThing heteroarene A heterocyclic compound formally derived from an arene by replacement of one or more methine (-C=) and/or vinylene (-CH=CH-) groups by trivalent or divalent heteroatoms, respectively, in such a way as to maintain the continuous pi-electron system characteristic of aromatic systems and a number of out-of-plane pi-electrons corresponding to the Hueckel rule (4n+2). FYPO_relaxed.owl CHEBI:59770 biolink:NamedThing cyclic acetal An acetal in the molecule of which the acetal carbon and one or both oxygen atoms thereon are members of a ring. FYPO_relaxed.owl CHEBI:33598 biolink:NamedThing carbocyclic compound A homocyclic compound in which all of the ring members are carbon atoms. FYPO_relaxed.owl CHEBI:33659 biolink:NamedThing organic aromatic compound FYPO_relaxed.owl CHEBI:5686 biolink:NamedThing heterocyclic compound A cyclic compound having as ring members atoms of at least two different elements. FYPO_relaxed.owl CHEBI:33670 biolink:NamedThing heteromonocyclic compound FYPO_relaxed.owl CHEBI:33671 biolink:NamedThing heteropolycyclic compound A polycyclic compound in which at least one of the rings contains at least one non-carbon atom. FYPO_relaxed.owl CHEBI:33672 biolink:NamedThing heterobicyclic compound A bicyclic compound in which at least one of the rings contains at least one skeletal heteroatom. FYPO_relaxed.owl CHEBI:24621 biolink:NamedThing hormone Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds. FYPO_relaxed.owl CHEBI:33280 biolink:NamedThing molecular messenger FYPO_relaxed.owl CHEBI:25512 biolink:NamedThing neurotransmitter An endogenous compound that is used to transmit information across the synapse between a neuron and another cell. FYPO_relaxed.owl CHEBI:26645 biolink:NamedThing semiochemical A molecular messenger released by an organism that affects the behaviour within or between species. FYPO_relaxed.owl CHEBI:62488 biolink:NamedThing signalling molecule A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell. FYPO_relaxed.owl CHEBI:48705 biolink:NamedThing agonist Substance which binds to cell receptors normally responding to naturally occurring substances and which produces a response of its own. FYPO_relaxed.owl CHEBI:63951 biolink:NamedThing estrogen receptor agonist An agonist at the estrogen receptor. FYPO_relaxed.owl CHEBI:64106 biolink:NamedThing protein kinase agonist An agonist that selectively binds to and activates a protein kinase receptor. FYPO_relaxed.owl CHEBI:91139 biolink:NamedThing elastin-laminin receptor agonist An agonist that selectively binds to and activates elastin-laminin receptors. FYPO_relaxed.owl CHEBI:35507 biolink:NamedThing natural product fundamental parent FYPO_relaxed.owl CHEBI:35552 biolink:NamedThing heterocyclic organic fundamental parent FYPO_relaxed.owl CHEBI:35573 biolink:NamedThing organic mancude parent FYPO_relaxed.owl CHEBI:35406 biolink:NamedThing oxoanion An oxoanion is an anion derived from an oxoacid by loss of hydron(s) bound to oxygen. FYPO_relaxed.owl CHEBI:33485 biolink:NamedThing chalcogen oxoanion FYPO_relaxed.owl CHEBI:24651 biolink:NamedThing hydroxides Hydroxides are chemical compounds containing a hydroxy group or salts containing hydroxide (OH(-)). FYPO_relaxed.owl CHEBI:25806 biolink:NamedThing oxygen molecular entity FYPO_relaxed.owl CHEBI:25741 biolink:NamedThing oxide An oxide is a chemical compound of oxygen with other chemical elements. FYPO_relaxed.owl CHEBI:33262 biolink:NamedThing elemental oxygen FYPO_relaxed.owl CHEBI:33608 biolink:NamedThing hydrogen molecular entity FYPO_relaxed.owl CHEBI:33692 biolink:NamedThing hydrides Hydrides are chemical compounds of hydrogen with other chemical elements. FYPO_relaxed.owl CHEBI:37577 biolink:NamedThing heteroatomic molecular entity A molecular entity consisting of two or more chemical elements. FYPO_relaxed.owl CHEBI:24866 biolink:NamedThing salt A salt is an assembly of cations and anions. FYPO_relaxed.owl CHEBI:33240 biolink:NamedThing coordination entity An assembly consisting of a central atom (usually metallic) to which is attached a surrounding array of other groups of atoms (ligands). FYPO_relaxed.owl CHEBI:33241 biolink:NamedThing oxoacid derivative FYPO_relaxed.owl CHEBI:35504 biolink:NamedThing addition compound An addition compound contains two or more simpler compounds that can be packed in a definite ratio into a crystal. The term covers donor-acceptor complexes (adducts) and a variety of lattice compounds. FYPO_relaxed.owl CHEBI:50312 biolink:NamedThing onium compound FYPO_relaxed.owl CHEBI:25754 biolink:NamedThing oxo carboxylic acid Any compound that has an aldehydic or ketonic group as well as a carboxylic acid group in the same molecule. FYPO_relaxed.owl CHEBI:35742 biolink:NamedThing tetracarboxylic acid An oxoacid containing four carboxy groups. FYPO_relaxed.owl CHEBI:46891 biolink:NamedThing azetidinecarboxylic acid A member of the class of azetidines that is azetidine substituted by at least one carboxy group at unspecified position. FYPO_relaxed.owl CHEBI:78574 biolink:NamedThing pyrimidinecarboxylic acid Any pyrimidine that bears one or more carboxylic acid substituents. FYPO_relaxed.owl CHEBI:24689 biolink:NamedThing hydroxycinnamic acid Any member of the class of cinnamic acids carrying one or more hydroxy substituents. FYPO_relaxed.owl CHEBI:2634 biolink:NamedThing amidine Derivatives of oxoacids RnE(=O)OH in which the hydroxy group is replaced by an amino group and the oxo group is replaced by =NR. In organic chemistry an unspecified amidine is commonly a carboxamidine. FYPO_relaxed.owl CHEBI:33267 biolink:NamedThing elemental nitrogen FYPO_relaxed.owl CHEBI:33455 biolink:NamedThing nitrogen oxoacid FYPO_relaxed.owl CHEBI:35106 biolink:NamedThing nitrogen hydride FYPO_relaxed.owl CHEBI:35715 biolink:NamedThing nitro compound A compound having a nitro group, -NO2 (free valence on nitrogen), which may be attached to carbon, nitrogen (as in nitramines), or oxygen (as in nitrates), among other elements (in the absence of specification, C-nitro compounds are usually implied). FYPO_relaxed.owl CHEBI:37533 biolink:NamedThing azo compound Derivatives of diazene with the general structure R-N=N-R'. FYPO_relaxed.owl CHEBI:48377 biolink:NamedThing imidic acid Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing =O by =NR; thus tautomers of amides. In organic chemistry an unspecified imidic acid is generally a carboximidic acid, RC(=NR)(OH). FYPO_relaxed.owl CHEBI:24745 biolink:NamedThing hydroxypyridine Any member of the class of pyridines with at least one hydroxy substituent. FYPO_relaxed.owl CHEBI:63946 biolink:NamedThing ferrozine free acid An arenesulfonic acid that is the 4,4'-disulfo derivative of 5,6-diphenyl-3-(pyridin-2-yl)-1,2,4-triazine. FYPO_relaxed.owl CHEBI:7934 biolink:NamedThing paromomycin An amino cyclitol glycoside that is the 1-O-(2-amino-2-deoxy-alpha-D-glucopyranoside) and the 3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranoside of 4,6-diamino-2,3-dihydroxycyclohexane (the 1R,2R,3S,4R,6S diastereoisomer). It is obtained from various Streptomyces species. A broad-spectrum antibiotic, it is used (generally as the sulfate salt) for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. FYPO_relaxed.owl CHEBI:42768 biolink:NamedThing geneticin An aminoglycoside antibiotic produced by Micromonospora rhodorangea. It blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. FYPO_relaxed.owl CHEBI:26410 biolink:NamedThing pyrazoles FYPO_relaxed.owl CHEBI:24782 biolink:NamedThing imide FYPO_relaxed.owl CHEBI:24828 biolink:NamedThing indoles Any compound containing an indole skeleton. FYPO_relaxed.owl CHEBI:24829 biolink:NamedThing indolones FYPO_relaxed.owl CHEBI:38631 biolink:NamedThing aminoalkylindole FYPO_relaxed.owl CHEBI:68807 biolink:NamedThing chaetoglobosin D A cytochalasan alkaloid found in Chaetomium globosum and Chaetomium brasiliense. FYPO_relaxed.owl CHEBI:24833 biolink:NamedThing oxoacid A compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). FYPO_relaxed.owl CHEBI:35923 biolink:NamedThing hydroperoxide A monosubstitution product of hydrogen peroxide, HOOH. FYPO_relaxed.owl CHEBI:60247 biolink:NamedThing silver ion A silver atom having a net electric charge. FYPO_relaxed.owl CHEBI:60248 biolink:NamedThing nickel ion A nickel atom having a net electric charge. FYPO_relaxed.owl CHEBI:60249 biolink:NamedThing lead ion A lead atom having a net electric charge. FYPO_relaxed.owl CHEBI:60270 biolink:NamedThing caesium ion A caesium atom having a net electric charge. FYPO_relaxed.owl CHEBI:60272 biolink:NamedThing aluminium ion An aluminium atom having a net electric charge. FYPO_relaxed.owl CHEBI:61310 biolink:NamedThing chromium ion An chromium atom having a net electric charge. FYPO_relaxed.owl CHEBI:85543 biolink:NamedThing bismuth ion A bismuth atom having a net electric charge. FYPO_relaxed.owl CHEBI:24836 biolink:NamedThing inorganic oxide FYPO_relaxed.owl CHEBI:33242 biolink:NamedThing inorganic hydride FYPO_relaxed.owl CHEBI:33628 biolink:NamedThing elemental aluminium FYPO_relaxed.owl CHEBI:25940 biolink:NamedThing peroxides Compounds of structure ROOR'. FYPO_relaxed.owl CHEBI:35580 biolink:NamedThing N-oxide FYPO_relaxed.owl CHEBI:33327 biolink:NamedThing silicon oxide FYPO_relaxed.owl CHEBI:24868 biolink:NamedThing organic salt FYPO_relaxed.owl CHEBI:35479 biolink:NamedThing alkali metal salt FYPO_relaxed.owl CHEBI:51082 biolink:NamedThing nitrate salt FYPO_relaxed.owl CHEBI:24846 biolink:NamedThing inositol phosphate FYPO_relaxed.owl CHEBI:33238 biolink:NamedThing monoatomic entity A monoatomic entity is a molecular entity consisting of a single atom. FYPO_relaxed.owl CHEBI:33433 biolink:NamedThing monoatomic halogen FYPO_relaxed.owl CHEBI:38632 biolink:NamedThing membrane transport modulator Any agent that affects the transport of molecular entities across a biological membrane. FYPO_relaxed.owl CHEBI:38808 biolink:NamedThing calcium channel modulator A membrane transport modulator that is able to regulate intracellular calcium levels. FYPO_relaxed.owl CHEBI:39000 biolink:NamedThing sodium channel modulator FYPO_relaxed.owl CHEBI:50510 biolink:NamedThing potassium channel modulator FYPO_relaxed.owl CHEBI:24873 biolink:NamedThing iron molecular entity FYPO_relaxed.owl CHEBI:33744 biolink:NamedThing iron group molecular entity FYPO_relaxed.owl CHEBI:82663 biolink:NamedThing elemental iron An elemental molecular entity in which all of the atoms have atomic number 26. FYPO_relaxed.owl CHEBI:26872 biolink:NamedThing terpene ketone Any terpenoid which contains a keto group. FYPO_relaxed.owl CHEBI:46640 biolink:NamedThing diketone A compound that contains two ketone functionalities. FYPO_relaxed.owl CHEBI:51721 biolink:NamedThing alpha,beta-unsaturated ketone A ketone of general formula R(1)R(2)C=CR(3)-C(=O)R(4) (R(4) =/= H) or R(1)C#C-C(=O)R(2) (R(2) =/= H) in which the ketonic C=O function is conjugated to an unsaturated C-C bond at the alpha,beta position. FYPO_relaxed.owl CHEBI:51838 biolink:NamedThing haloketone A ketone containing a halo group. FYPO_relaxed.owl CHEBI:51851 biolink:NamedThing ketonitrile A compound containing both ketone and nitrile functionalities. FYPO_relaxed.owl CHEBI:52395 biolink:NamedThing oxyketone A compound with the general formula R2C=O (R=/=H) where one or more of the R groups contains an oxy (-O-) group. FYPO_relaxed.owl CHEBI:76224 biolink:NamedThing aromatic ketone A ketone in which the carbonyl group is attached to an aromatic ring. FYPO_relaxed.owl CHEBI:24970 biolink:NamedThing ketohexose bisphosphate FYPO_relaxed.owl CHEBI:24972 biolink:NamedThing ketohexose phosphate FYPO_relaxed.owl CHEBI:35132 biolink:NamedThing ketose phosphate FYPO_relaxed.owl CHEBI:47878 biolink:NamedThing hexose phosphate A phospho sugar that is formally obtained from a hexose. FYPO_relaxed.owl CHEBI:24973 biolink:NamedThing ketohexose Any hexose containing a single ketone group. FYPO_relaxed.owl CHEBI:84076 biolink:NamedThing L-histidine derivative A proteinogenic amino acid derivative resulting from the formal reaction of L-histidine at the amino group, carboxy group, or the imidazolyl moiety, or from the replacement of any hydrogen of L-histidine by a heteroatom. FYPO_relaxed.owl CHEBI:84144 biolink:NamedThing L-phenylalanine derivative A proteinogenic amino acid derivative resulting from reaction of L-phenylalanine at the amino group or the carboxy group, or from the replacement of any hydrogen of L-phenylalanine by a heteroatom. FYPO_relaxed.owl CHEBI:34848 biolink:NamedThing mevastatin A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. FYPO_relaxed.owl CHEBI:40303 biolink:NamedThing lovastatin A fatty acid ester that is mevastatin carrying an additional methyl group on the carbobicyclic skeleton. It is used in as an anticholesteremic drug and has been found in fungal species such as Aspergillus terreus and Pleurotus ostreatus (oyster mushroom). FYPO_relaxed.owl CHEBI:48120 biolink:NamedThing anthracycline Anthracyclines are polyketides that have a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine. FYPO_relaxed.owl CHEBI:25154 biolink:NamedThing manganese molecular entity FYPO_relaxed.owl CHEBI:33743 biolink:NamedThing manganese group molecular entity FYPO_relaxed.owl CHEBI:35115 biolink:NamedThing elemental manganese FYPO_relaxed.owl CHEBI:25168 biolink:NamedThing mannosylinositol phosphorylceramide A class of complex phosphoglycosphingolipids with a mannose-inositol-P head group. As with other ceramide derivatives, substituents R(1) and R(2) vary with different sphingoid bases and fatty acyl moieties. FYPO_relaxed.owl CHEBI:26057 biolink:NamedThing phosphoglycosphingolipid FYPO_relaxed.owl CHEBI:60245 biolink:NamedThing inositol phosphoceramide A phosphosphingolipid in which an inositol residue and the ceramide moiety are linked via a phosphodiester bridge. The ceramide moiety contains substituents R(1) and R(2) which vary with different sphingoid bases and fatty acyl moieties. FYPO_relaxed.owl CHEBI:52684 biolink:NamedThing butanediol A member of the class of butanediols that is butane in which two of the hydrogens have been replaced by hydroxy groups. FYPO_relaxed.owl CHEBI:35113 biolink:NamedThing elemental mercury FYPO_relaxed.owl CHEBI:25213 biolink:NamedThing metal cation FYPO_relaxed.owl CHEBI:25414 biolink:NamedThing monoatomic monocation FYPO_relaxed.owl CHEBI:25430 biolink:NamedThing monoatomic polycation FYPO_relaxed.owl CHEBI:60242 biolink:NamedThing monovalent inorganic cation An atom or small molecule with a positive charge that does not contain carbon in covalent linkage, with a valency of one. FYPO_relaxed.owl CHEBI:64641 biolink:NamedThing divalent inorganic cation An inorganic cation with a valency of two. FYPO_relaxed.owl CHEBI:25216 biolink:NamedThing metalloporphyrin FYPO_relaxed.owl CHEBI:26214 biolink:NamedThing porphyrins Natural pigments containing a fundamental skeleton of four pyrrole nuclei united through the alpha-positions by four methine groups to form a macrocyclic structure. FYPO_relaxed.owl CHEBI:33861 biolink:NamedThing transition element coordination entity FYPO_relaxed.owl CHEBI:33909 biolink:NamedThing metallotetrapyrrole FYPO_relaxed.owl CHEBI:25224 biolink:NamedThing methanesulfonate A 1,1-diunsubstituted alkanesulfonate that is the conjugate base of methanesulfonic acid. FYPO_relaxed.owl CHEBI:62081 biolink:NamedThing 1,1-diunsubstituted alkanesulfonate An alkanesulfonate in which the carbon at position 1 is attached to at least two hydrogens. FYPO_relaxed.owl CHEBI:25348 biolink:NamedThing methylxanthine FYPO_relaxed.owl CHEBI:25350 biolink:NamedThing mevalonate A racemate composed of equimolar amounts of (R)- and (S)-mevalonate. FYPO_relaxed.owl CHEBI:60911 biolink:NamedThing racemate A racemate is an equimolar mixture of a pair of enantiomers. FYPO_relaxed.owl CHEBI:25351 biolink:NamedThing mevalonic acid A racemate composed of equimolar amounts of (R)- and (S)-mevalonic acid. FYPO_relaxed.owl CHEBI:47519 biolink:NamedThing ketoconazole A racemate consisting of equimolar amounts of (2R,4S)- and (2S,4R)-ketoconazole. FYPO_relaxed.owl CHEBI:4754 biolink:NamedThing econazole A racemate composed of equimolar amounts of (R)- and (S)-econazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. FYPO_relaxed.owl CHEBI:50145 biolink:NamedThing fenpropimorph A racemate comprising equimolar amounts of (R)- and (S)-fenpropimorph. It is a systemic fungicide, used to control a variety of fungal diseases in cereal crops. FYPO_relaxed.owl CHEBI:6923 biolink:NamedThing miconazole A racemate composed of equimolar amounts of (R)- and (S)-miconazole. Used (as its nitrate salt) to treat skin infections such as athlete's foot, jock itch, ringworm and other fungal skin infections. It inhibits the synthesis of ergosterol, a critical component of fungal cell membranes. FYPO_relaxed.owl CHEBI:81781 biolink:NamedThing tebuconazole A racemate composed of equimolar amounts of (R)- and (S)-tebuconazole. A fungicide effective against various smut and bunt diseases in cereals and other field crops. FYPO_relaxed.owl CHEBI:85577 biolink:NamedThing ormaplatin A racemate comprising equal amounts of (1R,2R)- and (1S,2S)-ormaplatin. FYPO_relaxed.owl CHEBI:9451 biolink:NamedThing terconazole A racemate consisting of equimolar amounts of (2R,4S)- and (2S,4R)-terconazole. It has broad-spectrum antifungal activitiy and is used for the treatment of vaginal yeast infections (Candida). FYPO_relaxed.owl CHEBI:38497 biolink:NamedThing respiratory-chain inhibitor FYPO_relaxed.owl CHEBI:38503 biolink:NamedThing EC 1.6.5.3 [NADH:ubiquinone reductase (H(+)-translocating)] inhibitor A respiratory-chain inhibitor that interferes with the action of the the enzyme NADH:ubiquinone reductase (H(+)-translocating), EC 1.6.5.3. FYPO_relaxed.owl CHEBI:34630 biolink:NamedThing chlorpropham A carbamate ester that is the isopropyl ester of 3-chlorophenylcarbamic acid. FYPO_relaxed.owl CHEBI:34892 biolink:NamedThing nocodazole A member of the class of benzimidazoles that is benzimidalole which is substituted at position 2 by a (methoxycarbonyl)amino group and at position 5 by a 2-thienoyl group. It is an antineoplastic agent that exerts its effect by depolymerising microtubules. FYPO_relaxed.owl CHEBI:87061 biolink:NamedThing carbamate fungicide Compounds that contain a carbamate ester moiety as a key feature of their structure and which have been used as fungicides. FYPO_relaxed.owl CHEBI:25367 biolink:NamedThing molecule Any polyatomic entity that is an electrically neutral entity consisting of more than one atom. FYPO_relaxed.owl CHEBI:25392 biolink:NamedThing naphthols Any hydroxynaphthalene derivative that has a single hydroxy substituent. FYPO_relaxed.owl CHEBI:26873 biolink:NamedThing terpenoid Any isoprenoid that is a natural product or related compound formally derived from isoprene units. Terpenoids may contain oxygen in various functional groups. This class is subdivided according to the number of carbon atoms in the parent terpene. The skeleton of terpenoids may differ from strict additivity of isoprene units by the loss or shift of a fragment, generally a methyl group. FYPO_relaxed.owl CHEBI:36615 biolink:NamedThing triterpenoid Any terpenoid derived from a triterpene. The term includes compounds in which the C30 skeleton of the parent triterpene has been rearranged or modified by the removal of one or more skeletal atoms (generally methyl groups). FYPO_relaxed.owl CHEBI:25411 biolink:NamedThing monoterpenols FYPO_relaxed.owl CHEBI:50902 biolink:NamedThing genotoxin A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells. FYPO_relaxed.owl CHEBI:25442 biolink:NamedThing mycotoxin Poisonous substance produced by fungi. FYPO_relaxed.owl CHEBI:27026 biolink:NamedThing toxin Poisonous substance produced by a biological organism such as a microbe, animal or plant. FYPO_relaxed.owl CHEBI:76946 biolink:NamedThing fungal metabolite Any eukaryotic metabolite produced during a metabolic reaction in fungi, the kingdom that includes microorganisms such as the yeasts and moulds. FYPO_relaxed.owl CHEBI:75772 biolink:NamedThing Saccharomyces cerevisiae metabolite Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae). FYPO_relaxed.owl CHEBI:76956 biolink:NamedThing Aspergillus metabolite Any fungal metabolite produced during a metabolic reaction in the mould, Aspergillus. FYPO_relaxed.owl CHEBI:76960 biolink:NamedThing Chaetomium metabolite Any fungal metabolite produced during a metabolic reaction in the mould, Chaetomium. FYPO_relaxed.owl CHEBI:76964 biolink:NamedThing Penicillium metabolite Any fungal metabolite produced during a metabolic reaction in Penicillium. FYPO_relaxed.owl CHEBI:25447 biolink:NamedThing myo-inositol pentakisphosphate FYPO_relaxed.owl CHEBI:38418 biolink:NamedThing 1,3-thiazoles FYPO_relaxed.owl CHEBI:45979 biolink:NamedThing thiabendazole A member of the class of benzimidazoles carrying a 1,3-thiazol-4-yl substituent at position 2. A mainly post-harvest fungicide used to control a wide range of diseases including Aspergillus, Botrytis, Cladosporium and Fusarium. FYPO_relaxed.owl CHEBI:48879 biolink:NamedThing bi-1,3-thiazole FYPO_relaxed.owl CHEBI:25471 biolink:NamedThing naphthalenemonosulfonate FYPO_relaxed.owl CHEBI:25478 biolink:NamedThing naphthalenesulfonate FYPO_relaxed.owl CHEBI:50012 biolink:NamedThing 4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonate An arenesulfonate arising from deprotonation of the sulfo groups of 4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonic acid. FYPO_relaxed.owl CHEBI:36526 biolink:NamedThing acidic glycosphingolipid FYPO_relaxed.owl CHEBI:27563 biolink:NamedThing arsenic atom FYPO_relaxed.owl CHEBI:25807 biolink:NamedThing organooxygen heterocyclic antibiotic FYPO_relaxed.owl CHEBI:25567 biolink:NamedThing nitrous acid FYPO_relaxed.owl CHEBI:48107 biolink:NamedThing nitric acid A nitrogen oxoacid of formula HNO3 in which the nitrogen atom is bonded to a hydroxy group and by equivalent bonds to the remaining two oxygen atoms. FYPO_relaxed.owl CHEBI:25609 biolink:NamedThing nucleotide-sugar FYPO_relaxed.owl CHEBI:42068 biolink:NamedThing idarubicin FYPO_relaxed.owl CHEBI:61749 biolink:NamedThing enfumafungin A triterpene glycoside and hemiacetal isolated from a fermentation of Hormonema sp. and which specifically inhibits glucan synthesis in fungal cells. FYPO_relaxed.owl CHEBI:63383 biolink:NamedThing heptose derivative A monosaccharide derivative that is formally obtained from a heptose. FYPO_relaxed.owl CHEBI:63385 biolink:NamedThing hexose derivative A monosaccharide derivative that is formally obtained from a hexose. FYPO_relaxed.owl CHEBI:63409 biolink:NamedThing pentose derivative A monosaccharide derivative that is formally obtained from a pentose. FYPO_relaxed.owl CHEBI:57560 biolink:NamedThing long-chain fatty acid anion A fatty acid anion with a chain length of C13 to C22. FYPO_relaxed.owl CHEBI:85150 biolink:NamedThing (9Z)-12-hydroxyoctadec-9-enoate A hydroxy fatty acid anion that is the conjugate base of (9Z)-12-hydroxyoctadec-9-enoic acid, obtained by deprotonation of the carboxy group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:78125 biolink:NamedThing fatty acid anion 18:0 Any saturated fatty acid anion containing 18 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. FYPO_relaxed.owl CHEBI:83955 biolink:NamedThing 2-saturated fatty acid anion A fatty acid anion obtained by deprotonation of the carboxy group of any 2-saturated fatty acid. FYPO_relaxed.owl CHEBI:78117 biolink:NamedThing fatty acid anion 8:0 Any saturated fatty acid anion containing 8 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. FYPO_relaxed.owl CHEBI:26020 biolink:NamedThing phosphate Salts and esters of phosphoric and oligophosphoric acids and their chalcogen analogues. In inorganic chemistry, the term is also used to describe anionic coordination entities with phosphorus as central atom. FYPO_relaxed.owl CHEBI:25704 biolink:NamedThing organic sulfate Compounds of the general formula SO3HOR where R is an organyl group FYPO_relaxed.owl CHEBI:26820 biolink:NamedThing sulfates Salts and esters of sulfuric acid FYPO_relaxed.owl CHEBI:35892 biolink:NamedThing phosphoranes lambda(5)-phosphane and its hydrocarbyl derivatives. By extension the term also applies to phosphonium ylides. FYPO_relaxed.owl CHEBI:36360 biolink:NamedThing phosphorus oxoacids and derivatives FYPO_relaxed.owl CHEBI:25712 biolink:NamedThing organoselenium compound An organoselenium compound is a compound containing at least one carbon-selenium bond. FYPO_relaxed.owl CHEBI:26628 biolink:NamedThing selenium molecular entity FYPO_relaxed.owl CHEBI:36961 biolink:NamedThing chalcocarbonic acid FYPO_relaxed.owl CHEBI:37863 biolink:NamedThing chalcoperoxol FYPO_relaxed.owl CHEBI:25717 biolink:NamedThing organotin compound FYPO_relaxed.owl CHEBI:27008 biolink:NamedThing tin molecular entity FYPO_relaxed.owl CHEBI:25722 biolink:NamedThing orotidine A nucleoside formed by attaching orotic acid to a ribose ring via a beta-N(1)-glycosidic bond. FYPO_relaxed.owl CHEBI:35703 biolink:NamedThing xenobiotic A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means. FYPO_relaxed.owl CHEBI:39317 biolink:NamedThing growth regulator Any chemical substance that inhibits the life-cycle of an organism. FYPO_relaxed.owl CHEBI:52208 biolink:NamedThing biophysical role FYPO_relaxed.owl CHEBI:52209 biolink:NamedThing aetiopathogenetic role A role played by the molecular entity or part thereof which causes the development of a pathological process. FYPO_relaxed.owl CHEBI:52210 biolink:NamedThing pharmacological role A biological role which describes how a drug interacts within a biological system and how the interactions affect its medicinal properties. FYPO_relaxed.owl CHEBI:52211 biolink:NamedThing physiological role FYPO_relaxed.owl CHEBI:53000 biolink:NamedThing epitope The biological role played by a material entity when bound by a receptor of the adaptive immune system. Specific site on an antigen to which an antibody binds. FYPO_relaxed.owl CHEBI:59174 biolink:NamedThing hapten Any substance capable of eliciting an immune response only when attached to a large carrier such as a protein. Examples include dinitrophenols; oligosaccharides; peptides; and heavy metals. FYPO_relaxed.owl CHEBI:64909 biolink:NamedThing poison Any substance that causes disturbance to organisms by chemical reaction or other activity on the molecular scale, when a sufficient quantity is absorbed by the organism. FYPO_relaxed.owl CHEBI:68509 biolink:NamedThing glutathione depleting agent A compound which causes a reduction in the levels of glutathione in cells. FYPO_relaxed.owl CHEBI:2580 biolink:NamedThing unsaturated fatty acid anion Any fatty acid anion containing at least one C-C unsaturated bond; formed by deprotonation of the carboxylic acid moiety. FYPO_relaxed.owl CHEBI:58950 biolink:NamedThing very long-chain fatty acid anion Any fatty acid anion with a chain length greater than C22. FYPO_relaxed.owl CHEBI:58953 biolink:NamedThing saturated fatty acid anion Any fatty acid anion in which there is no C-C unsaturation. FYPO_relaxed.owl CHEBI:58955 biolink:NamedThing branched-chain fatty acid anion Any fatty acid anion with a carbon side-chain or isopropyl termination. FYPO_relaxed.owl CHEBI:59203 biolink:NamedThing straight-chain fatty acid anion A fatty acid anion formed by deprotonation of the carboxylic acid functional group of a straight-chain fatty acid. FYPO_relaxed.owl CHEBI:59558 biolink:NamedThing medium-chain fatty acid anion A fatty acid anion resulting from the deprotonation of the carboxylic acid moiety of a medium-chain fatty acid. FYPO_relaxed.owl CHEBI:61008 biolink:NamedThing nitrogen-containing fatty acid anion A fatty acid anion arising from deprotonation of the carboxylic acid group of any nitrogen-containing fatty acid. FYPO_relaxed.owl CHEBI:30452 biolink:NamedThing tellurium atom FYPO_relaxed.owl CHEBI:26835 biolink:NamedThing sulfur molecular entity FYPO_relaxed.owl CHEBI:33305 biolink:NamedThing tellurium molecular entity FYPO_relaxed.owl CHEBI:36902 biolink:NamedThing chalcogen hydride FYPO_relaxed.owl CHEBI:35131 biolink:NamedThing aldose phosphate FYPO_relaxed.owl CHEBI:84055 biolink:NamedThing pentose phosphate Any phospho sugar that is the phosphate derivative of pentose. FYPO_relaxed.owl CHEBI:25987 biolink:NamedThing phenylalanyl group FYPO_relaxed.owl CHEBI:33658 biolink:NamedThing arene Any monocyclic or polycyclic aromatic hydrocarbon. FYPO_relaxed.owl CHEBI:64459 biolink:NamedThing biaryl An organic aromatic compound whose structure contains two aromatic rings or ring systems, joined to each other by a single bond. FYPO_relaxed.owl CHEBI:26013 biolink:NamedThing pheromone A semiochemical used in olfactory communication between organisms of the same species eliciting a change in sexual or social behaviour. FYPO_relaxed.owl CHEBI:26079 biolink:NamedThing phosphoric acid derivative FYPO_relaxed.owl CHEBI:26034 biolink:NamedThing phosphatidylinositol 3-phosphate A phosphatidylinositol monophosphate carrying the phosphate group at the 3-position. FYPO_relaxed.owl CHEBI:26036 biolink:NamedThing phosphatidylinositol monophosphate FYPO_relaxed.owl CHEBI:37530 biolink:NamedThing phosphatidylinositol 4-phosphate A phosphatidylinositol monophosphate carrying the phosphate group at the 4-position. FYPO_relaxed.owl CHEBI:28765 biolink:NamedThing phosphatidylinositol phosphate Any member of the phosphoinositide family of compounds, of which seven occur naturally. FYPO_relaxed.owl CHEBI:26078 biolink:NamedThing phosphoric acid A phosphorus oxoacid that consists of one oxo and three hydroxy groups joined covalently to a central phosphorus atom. FYPO_relaxed.owl CHEBI:59698 biolink:NamedThing phosphoric acids Compounds containing one or more phosphoric acid units. FYPO_relaxed.owl CHEBI:36359 biolink:NamedThing phosphorus oxoacid derivative FYPO_relaxed.owl CHEBI:26087 biolink:NamedThing photosynthetic electron-transport chain inhibitor FYPO_relaxed.owl CHEBI:26089 biolink:NamedThing photosystem-II inhibitor FYPO_relaxed.owl CHEBI:26124 biolink:NamedThing phytosteroid FYPO_relaxed.owl CHEBI:26130 biolink:NamedThing biological pigment An endogenous molecular entity that results in a colour of an organism as the consequence of the selective absorption of light. FYPO_relaxed.owl CHEBI:26155 biolink:NamedThing plant growth regulator A chemical, natural or artificial, that can affect the rate of growth of a plant. FYPO_relaxed.owl CHEBI:26179 biolink:NamedThing polyether antibiotic FYPO_relaxed.owl CHEBI:36309 biolink:NamedThing cyclic tetrapyrrole FYPO_relaxed.owl CHEBI:26216 biolink:NamedThing potassium atom FYPO_relaxed.owl CHEBI:26708 biolink:NamedThing sodium atom FYPO_relaxed.owl CHEBI:30514 biolink:NamedThing caesium atom FYPO_relaxed.owl CHEBI:26217 biolink:NamedThing potassium molecular entity FYPO_relaxed.owl CHEBI:33296 biolink:NamedThing alkali metal molecular entity A molecular entity containing one or more atoms of an alkali metal. FYPO_relaxed.owl CHEBI:26712 biolink:NamedThing sodium molecular entity FYPO_relaxed.owl CHEBI:37128 biolink:NamedThing caesium molecular entity FYPO_relaxed.owl CHEBI:37247 biolink:NamedThing elemental potassium FYPO_relaxed.owl CHEBI:26714 biolink:NamedThing sodium salt Any alkali metal salt having sodium(1+) as the cation. FYPO_relaxed.owl CHEBI:46773 biolink:NamedThing hydroxypyrrolidine FYPO_relaxed.owl CHEBI:26932 biolink:NamedThing tetrapyrrole A natural pigment containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next. FYPO_relaxed.owl CHEBI:38179 biolink:NamedThing monocyclic heteroarene FYPO_relaxed.owl CHEBI:26509 biolink:NamedThing quinoline alkaloid FYPO_relaxed.owl CHEBI:38958 biolink:NamedThing indole alkaloid An alkaloid containing an indole skeleton. FYPO_relaxed.owl CHEBI:67606 biolink:NamedThing sampangine A copyrine alkaloid with formula C15H8N2O, extracted from several plants including the stem bark of Cananga odorata. It is a heme biosynthesis inhibitor and exhibits antifungal and anticancer properties. FYPO_relaxed.owl CHEBI:26389 biolink:NamedThing purine deoxyribonucleoside triphosphate FYPO_relaxed.owl CHEBI:67203 biolink:NamedThing N,N'-(p-xylylidene)bis(aminoguanidine) A guanidine derivative comprised of two carbamimidamido (guanidino) groups, each linked via one of their amino nitrogens to the imino nitrogens of 1,4-phenylenedimethanimine. FYPO_relaxed.owl CHEBI:84338 biolink:NamedThing synthalin A A member of the class of guanidines that is decane having guanidino groups at the 1- and 10-positions. FYPO_relaxed.owl CHEBI:38314 biolink:NamedThing pyrazines FYPO_relaxed.owl CHEBI:52717 biolink:NamedThing bortezomib L-Phenylalaninamide substituted at the amide nitrogen by a 1-(dihydroxyboranyl)-3-methylbutyl group and at N(alpha) by a pyrazin-2-ylcarbonyl group. It is a dipeptidyl boronic acid that reversibly inhibits the 26S proteasome. FYPO_relaxed.owl CHEBI:26390 biolink:NamedThing purine 2'-deoxyribonucleotide FYPO_relaxed.owl CHEBI:26436 biolink:NamedThing pyrimidine 2'-deoxyribonucleotide FYPO_relaxed.owl CHEBI:26400 biolink:NamedThing purine ribonucleotide Any ribonucleotide that has a purine nucleobase. FYPO_relaxed.owl CHEBI:61292 biolink:NamedThing guanyl nucleotide A nucleotide having guanine as the base. FYPO_relaxed.owl CHEBI:61293 biolink:NamedThing adenyl nucleotide A nucleotide having adenine as the base. FYPO_relaxed.owl CHEBI:26396 biolink:NamedThing purine ribonucleoside diphosphate FYPO_relaxed.owl CHEBI:26442 biolink:NamedThing pyrimidine ribonucleoside diphosphate FYPO_relaxed.owl CHEBI:26446 biolink:NamedThing pyrimidine ribonucleotide FYPO_relaxed.owl CHEBI:37015 biolink:NamedThing ribonucleoside 5'-phosphate FYPO_relaxed.owl CHEBI:39447 biolink:NamedThing pyrimidines Any compound having a pyrimidine as part of its structure. FYPO_relaxed.owl CHEBI:26433 biolink:NamedThing pyrimidine 2'-deoxyribonucleoside diphosphate FYPO_relaxed.owl CHEBI:26435 biolink:NamedThing pyrimidine deoxyribonucleoside triphosphate FYPO_relaxed.owl CHEBI:26438 biolink:NamedThing pyrimidine nucleoside monophosphate FYPO_relaxed.owl CHEBI:26558 biolink:NamedThing ribonucleoside monophosphate FYPO_relaxed.owl CHEBI:26443 biolink:NamedThing pyrimidine ribonucleoside monophosphate FYPO_relaxed.owl CHEBI:37010 biolink:NamedThing ribonucleoside 5'-monophosphate FYPO_relaxed.owl CHEBI:59137 biolink:NamedThing (8xi)-cinchonan Cinchonan or its (8S)-epimer. FYPO_relaxed.owl CHEBI:37293 biolink:NamedThing 1-ribosylimidazole FYPO_relaxed.owl CHEBI:26588 biolink:NamedThing 1,3,5-triazines Any compound with a 1,3,5-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 3 and 5 of the core benzene ring structure. FYPO_relaxed.owl CHEBI:39410 biolink:NamedThing 1,2,4-triazines Any compound with a 1,2,4-triazine skeleton, in which nitrogen atoms replace carbon at positions 1, 2 and 4 of the core benzene ring structure. FYPO_relaxed.owl CHEBI:26629 biolink:NamedThing selenoamino acid FYPO_relaxed.owl CHEBI:37142 biolink:NamedThing organoiodine compound An organoiodine compound is a compound containing at least one carbon-iodine bond. FYPO_relaxed.owl CHEBI:38830 biolink:NamedThing 1-benzofurans A member of the class of benzofurans consisting of a 1-benzofuran skeleton and its substituted derivatives thereof. FYPO_relaxed.owl CHEBI:26677 biolink:NamedThing silicon molecular entity FYPO_relaxed.owl CHEBI:33585 biolink:NamedThing lead molecular entity FYPO_relaxed.owl CHEBI:26710 biolink:NamedThing sodium chloride An inorganic chloride salt having sodium(1+) as the counterion. FYPO_relaxed.owl CHEBI:32588 biolink:NamedThing potassium chloride A metal chloride salt with a K(+) counterion. FYPO_relaxed.owl CHEBI:6636 biolink:NamedThing magnesium dichloride A magnesium salt comprising of two chlorine atoms bound to a magnesium atom. FYPO_relaxed.owl CHEBI:278547 biolink:NamedThing sodium azide The sodium salt of hydrogen azide (hydrazoic acid). FYPO_relaxed.owl CHEBI:29678 biolink:NamedThing sodium arsenite An inoganic sodium salt with formula with formula NaAsO2. FYPO_relaxed.owl CHEBI:35607 biolink:NamedThing trisodium vanadate An inorganic sodium salt of formula Na3VO4 containing the tetrahedral VO4(3-) FYPO_relaxed.owl CHEBI:37246 biolink:NamedThing elemental sodium FYPO_relaxed.owl CHEBI:37826 biolink:NamedThing sulfuric acid derivative FYPO_relaxed.owl CHEBI:87113 biolink:NamedThing antibiotic antifungal drug Any antibiotic antifungal agent used to treat fungal infections in humans or animals. FYPO_relaxed.owl CHEBI:33402 biolink:NamedThing sulfur oxoacid FYPO_relaxed.owl CHEBI:33424 biolink:NamedThing sulfur oxoacid derivative FYPO_relaxed.owl CHEBI:48343 biolink:NamedThing disulfide Compounds of structure RSSR'. FYPO_relaxed.owl CHEBI:26836 biolink:NamedThing sulfuric acid A sulfur oxoacid that consists of two oxo and two hydroxy groups joined covalently to a central sulfur atom. FYPO_relaxed.owl CHEBI:29214 biolink:NamedThing sulfonic acid FYPO_relaxed.owl CHEBI:48854 biolink:NamedThing sulfurous acid FYPO_relaxed.owl CHEBI:47882 biolink:NamedThing cyclic polypyrrole FYPO_relaxed.owl CHEBI:26961 biolink:NamedThing thiophenes Compounds containing at least one thiophene ring. FYPO_relaxed.owl CHEBI:36688 biolink:NamedThing heterotricyclic compound FYPO_relaxed.owl CHEBI:75763 biolink:NamedThing eukaryotic metabolite Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms. FYPO_relaxed.owl CHEBI:75787 biolink:NamedThing prokaryotic metabolite Any metabolite produced during a metabolic reaction in prokaryotes, the taxon that include members of domains such as the bacteria and archaea. FYPO_relaxed.owl CHEBI:76206 biolink:NamedThing xenobiotic metabolite Any metabolite produced by metabolism of a xenobiotic compound. FYPO_relaxed.owl CHEBI:76507 biolink:NamedThing marine metabolite Any metabolite produced during a metabolic reaction in marine macro- and microorganisms. FYPO_relaxed.owl CHEBI:78675 biolink:NamedThing fundamental metabolite Any metabolite produced by all living cells. FYPO_relaxed.owl CHEBI:50910 biolink:NamedThing neurotoxin A poison that interferes with the functions of the nervous system. FYPO_relaxed.owl CHEBI:61015 biolink:NamedThing nephrotoxin A poison that interferes with the function of the kidneys. FYPO_relaxed.owl CHEBI:27027 biolink:NamedThing micronutrient Any nutrient required in small quantities by organisms throughout their life in order to orchestrate a range of physiological functions. FYPO_relaxed.owl CHEBI:33284 biolink:NamedThing nutrient A nutrient is a food component that an organism uses to survive and grow. FYPO_relaxed.owl CHEBI:33937 biolink:NamedThing macronutrient Any nutrient required in large quantities by organisms throughout their life in order to orchestrate a range of physiological functions. Macronutrients are usually chemical elements (carbon, hydrogen, nitrogen, oxygen, phosphorus and sulfur) that humans consume in the largest quantities. Calcium, sodium, magnesium and potassium are sometimes included as macronutrients because they are required in relatively large quantities compared with other vitamins and minerals. FYPO_relaxed.owl CHEBI:27086 biolink:NamedThing tributylstannane FYPO_relaxed.owl CHEBI:27134 biolink:NamedThing trimethylxanthine FYPO_relaxed.owl CHEBI:37838 biolink:NamedThing carboacyl group A carboacyl group is a group formed by loss of at least one OH from the carboxy group of a carboxylic acid. FYPO_relaxed.owl CHEBI:27273 biolink:NamedThing vanadic acid FYPO_relaxed.owl CHEBI:35166 biolink:NamedThing vanadium coordination entity FYPO_relaxed.owl CHEBI:30528 biolink:NamedThing vanadium oxoanion FYPO_relaxed.owl CHEBI:36265 biolink:NamedThing transition element oxoacid FYPO_relaxed.owl CHEBI:27275 biolink:NamedThing vanadium molecular entity FYPO_relaxed.owl CHEBI:33746 biolink:NamedThing vanadium group molecular entity FYPO_relaxed.owl CHEBI:37253 biolink:NamedThing elemental zinc FYPO_relaxed.owl CHEBI:27369 biolink:NamedThing zwitterion A neutral compound having formal unit electrical charges of opposite sign on non-adjacent atoms. Sometimes referred to as inner salts, dipolar ions (a misnomer). FYPO_relaxed.owl CHEBI:51150 biolink:NamedThing ylide A compound in which an anionic site Y(-) is attached directly to a heteroatom X(+) (usually nitrogen, phosphorus or sulfur) carrying a formal positive charge. FYPO_relaxed.owl CHEBI:47901 biolink:NamedThing alkanesulfonic acid Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an alkyl group. FYPO_relaxed.owl CHEBI:27380 biolink:NamedThing (1->6)-beta-D-glucan FYPO_relaxed.owl CHEBI:37671 biolink:NamedThing (1->3)-beta-D-glucan A beta-D-glucan in which the glucose units are connected by (1->3) linkages. FYPO_relaxed.owl CHEBI:27504 biolink:NamedThing mitomycin C FYPO_relaxed.owl CHEBI:30968 biolink:NamedThing azetidine FYPO_relaxed.owl CHEBI:35356 biolink:NamedThing dicarboximide An imide in which the two acyl substituents on nitrogen are carboacyl groups. FYPO_relaxed.owl CHEBI:5435 biolink:NamedThing piperidine-2,6-dione A dicarboximide that is piperidine which is substituted by oxo groups at positions 2 and 6. FYPO_relaxed.owl CHEBI:49318 biolink:NamedThing piperidine antibiotic FYPO_relaxed.owl CHEBI:87114 biolink:NamedThing antibiotic fungicide Any antibiotic antifungal agent that has been used as a fungicide. FYPO_relaxed.owl CHEBI:75885 biolink:NamedThing 2-pyranones A pyranone based on the structure of 2H-pyran-2-one and its substituted derivatives. FYPO_relaxed.owl CHEBI:51323 biolink:NamedThing cinchona alkaloid An alkaloid based on a cinchonan skeleton. FYPO_relaxed.owl CHEBI:27666 biolink:NamedThing actinomycin D FYPO_relaxed.owl CHEBI:27680 biolink:NamedThing galactomannan A heteroglycan consisting of a mannan backbone with galactose side groups. FYPO_relaxed.owl CHEBI:61298 biolink:NamedThing D-glucose- and/or D-galactose-substituted mannan A heteroglycan in which a backbone composed of D-mannose units is substituted with D-glucose and/or D-galactose units. FYPO_relaxed.owl CHEBI:27698 biolink:NamedThing vanadium atom FYPO_relaxed.owl CHEBI:33347 biolink:NamedThing vanadium group element atom FYPO_relaxed.owl CHEBI:27732 biolink:NamedThing caffeine A trimethylxanthine in which the three methyl groups are located at positions 1, 3, and 7. A purine alkaloid that occurs naturally in tea and coffee. FYPO_relaxed.owl CHEBI:35195 biolink:NamedThing surfactant A substance which lowers the surface tension of the medium in which it is dissolved, and/or the interfacial tension with other phases, and, accordingly, is positively adsorbed at the liquid/vapour and/or at other interfaces. FYPO_relaxed.owl CHEBI:27822 biolink:NamedThing 2-aminobenzimidazole A member of the class of benzimidazoles that is benzimidazole in which the hydrogen at position 2 is replaced by an amino group. FYPO_relaxed.owl CHEBI:36622 biolink:NamedThing benzimidazole A mancude organic heterobicyclic parent that is a heterocyclic organic compound comprising fused benzene and imidazole rings. FYPO_relaxed.owl CHEBI:87036 biolink:NamedThing benzimidazole fungicide Compounds that contain a benzimidazole moiety as a key feature of their structure and which have been used as fungicides. FYPO_relaxed.owl CHEBI:87064 biolink:NamedThing benzimidazolylcarbamate fungicide Any carbamate fungicide that contains a benzimidazolyl group attached to the nitrogen of the carbamate moiety. FYPO_relaxed.owl CHEBI:27899 biolink:NamedThing cisplatin A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups). FYPO_relaxed.owl CHEBI:51214 biolink:NamedThing diamminedichloroplatinum FYPO_relaxed.owl CHEBI:35852 biolink:NamedThing transplatin A diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a trans planar configuration around the central platinum ion. Unlike its cis-isomer, cisplatin, it does not exhibit any useful pharmacological effect and is toxic. FYPO_relaxed.owl CHEBI:27955 biolink:NamedThing streptamine An amino cyclitol consisting of scyllo-inositol with the hydroxy groups at positions 1 and 3 replaced by unsubstituted amino groups. FYPO_relaxed.owl CHEBI:27961 biolink:NamedThing 1,8-cineole FYPO_relaxed.owl CHEBI:28073 biolink:NamedThing chromium atom A chromium group element atom that has atomic number 24. FYPO_relaxed.owl CHEBI:33350 biolink:NamedThing chromium group element atom FYPO_relaxed.owl CHEBI:28685 biolink:NamedThing molybdenum atom FYPO_relaxed.owl CHEBI:28694 biolink:NamedThing copper atom FYPO_relaxed.owl CHEBI:36773 biolink:NamedThing camphor A cyclic monoterpene ketone that is bornane bearing an oxo substituent at position 2. A naturally occurring monoterpenoid. FYPO_relaxed.owl CHEBI:28100 biolink:NamedThing (1->3)-alpha-D-glucan An alpha-D-glucan in which the glucose units are connected by (1->3) linkages. FYPO_relaxed.owl CHEBI:28163 biolink:NamedThing iron(III) hydroxamate A complex between iron(III) and three hydroxamic acid groups, used for iron transport. FYPO_relaxed.owl CHEBI:5975 biolink:NamedThing iron chelate FYPO_relaxed.owl CHEBI:84734 biolink:NamedThing Fe(III)-complexed siderophore Any iron chelate that consists of a siderophore complexed to iron(III) FYPO_relaxed.owl CHEBI:28201 biolink:NamedThing rotenone A member of the class of rotenones that consists of 1,2,12,12a-tetrahydrochromeno[3,4-b]furo[2,3-h]chromen-6(6aH)-one substituted at position 2 by a prop-1-en-2-yl group and at positions 8 and 9 by methoxy groups (the 2R,6aS,12aS-isomer). A non-systemic insecticide, it is the principal insecticidal constituent of derris (the dried rhizome and root of Derris elliptica). FYPO_relaxed.owl CHEBI:28494 biolink:NamedThing cardiolipin A phosphatidylglycerol composed of two molecules of phosphatidic acid covalently linked to a molecule of glycerol. FYPO_relaxed.owl CHEBI:28545 biolink:NamedThing valinomycin A twelve-membered cyclodepsipeptide composed of three repeating D-alpha-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl units joined in sequence. An antibiotic found in several Streptomyces strains. FYPO_relaxed.owl CHEBI:51026 biolink:NamedThing macrocycle A cyclic compound containing nine or more atoms as part of the cyclic system. FYPO_relaxed.owl CHEBI:28575 biolink:NamedThing L-glutamate methyl ester A L-glutamyl ester that is the alpha-methyl ester derivative of L-glutamic acid. FYPO_relaxed.owl CHEBI:28592 biolink:NamedThing ricinoleic acid A (9Z)-12-hydroxyoctadec-9-enoic acid in which the 12-hydroxy group has R-configuration.. FYPO_relaxed.owl CHEBI:28593 biolink:NamedThing quinidine A cinchona alkaloid consisting of cinchonine with the hydrogen at the 6-position of the quinoline ring substituted by methoxy. FYPO_relaxed.owl CHEBI:35933 biolink:NamedThing cinchonan FYPO_relaxed.owl CHEBI:28976 biolink:NamedThing carbonic acid FYPO_relaxed.owl CHEBI:33366 biolink:NamedThing copper group element atom FYPO_relaxed.owl CHEBI:30512 biolink:NamedThing silver atom FYPO_relaxed.owl CHEBI:28741 biolink:NamedThing sodium fluoride A metal fluoride salt with a Na(+) counterion. FYPO_relaxed.owl CHEBI:49322 biolink:NamedThing anthracycline antibiotic An organic compound that has a tetrahydronaphthacenedione ring structure attached by a glycosidic linkage to the amino sugar daunosamine and which exhibits antibiotic activity. FYPO_relaxed.owl CHEBI:28749 biolink:NamedThing aryl beta-D-glucoside FYPO_relaxed.owl CHEBI:28794 biolink:NamedThing coumarin A chromenone having the keto group located at the 2-position. FYPO_relaxed.owl CHEBI:28869 biolink:NamedThing menadione A member of the class of 1,4-naphthoquinones that is 1,4-naphthoquinone which is substituted at position 2 by a methyl group. It is used as a nutritional supplement and for the treatment of hypoprothrombinemia. FYPO_relaxed.owl CHEBI:62749 biolink:NamedThing 2-acylglycerophosphoinositol A glycerophosphoinositol acylated at O(2) of the glycerol moiety. FYPO_relaxed.owl CHEBI:64931 biolink:NamedThing lysophosphatidyl-1D-myo-inositol A glycerophosphoinositol resulting from partial hydrolysis of a phosphatidyl-1D-myo-inositol, which removes one of the fatty acid groups. The structure is depicted in the image where R(1) = acyl, R(2) = H or where R(1) = H, R(2) = acyl. FYPO_relaxed.owl CHEBI:28907 biolink:NamedThing 2,3-bisphosphoglyceric acid A bisphosphoglyceric acid that is glyceric acid carrying two phospho substituents at positions 2 and 3. FYPO_relaxed.owl CHEBI:63455 biolink:NamedThing tetronic acid derivative An aldonic acid derivative that is formally obtained from a tetronic acid. FYPO_relaxed.owl CHEBI:28938 biolink:NamedThing ammonium An onium cation obtained by protonation of ammonia. FYPO_relaxed.owl CHEBI:29449 biolink:NamedThing hydrogen azide FYPO_relaxed.owl CHEBI:30096 biolink:NamedThing diazene FYPO_relaxed.owl CHEBI:30103 biolink:NamedThing diazenide FYPO_relaxed.owl CHEBI:50155 biolink:NamedThing triazane FYPO_relaxed.owl CHEBI:50313 biolink:NamedThing onium cation Mononuclear cations derived by addition of a hydron to a mononuclear parent hydride of the pnictogen, chalcogen and halogen families. FYPO_relaxed.owl CHEBI:50314 biolink:NamedThing fluoronium FYPO_relaxed.owl CHEBI:50315 biolink:NamedThing chloronium FYPO_relaxed.owl CHEBI:50316 biolink:NamedThing bromonium FYPO_relaxed.owl CHEBI:29101 biolink:NamedThing sodium(1+) A monoatomic monocation obtained from sodium. FYPO_relaxed.owl CHEBI:29103 biolink:NamedThing potassium(1+) A monoatomic monocation obtained from potassium. FYPO_relaxed.owl CHEBI:49713 biolink:NamedThing lithium(1+) FYPO_relaxed.owl CHEBI:28997 biolink:NamedThing 2'-deoxyinosine A purine 2'-deoxyribonucleoside that is inosine in which the hydroxy group at position 2' is replaced by a hydrogen. FYPO_relaxed.owl CHEBI:29032 biolink:NamedThing (R)-pantothenate A pantothenate that is the conjugate base of (R)-pantothenic acid, obtained by deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:46905 biolink:NamedThing (R)-pantothenic acid A pantothenic acid having R-configuration. FYPO_relaxed.owl CHEBI:33504 biolink:NamedThing alkali metal cation FYPO_relaxed.owl CHEBI:39123 biolink:NamedThing calcium cation FYPO_relaxed.owl CHEBI:29125 biolink:NamedThing arsenate(3-) An arsenate ion resulting from the removal of three protons from arsenic acid. FYPO_relaxed.owl CHEBI:48597 biolink:NamedThing arsenate(2-) An arsenate ion resulting from the removal of two protons from arsenic acid. FYPO_relaxed.owl CHEBI:48600 biolink:NamedThing arsenate(1-) An arsenate ion resulting from the removal of one proton from arsenic acid. FYPO_relaxed.owl CHEBI:37750 biolink:NamedThing chlorine oxide FYPO_relaxed.owl CHEBI:29277 biolink:NamedThing dinitride(2-) FYPO_relaxed.owl CHEBI:33266 biolink:NamedThing diatomic nitrogen FYPO_relaxed.owl CHEBI:29281 biolink:NamedThing alkyl sulfate FYPO_relaxed.owl CHEBI:29321 biolink:NamedThing sodium nitroprusside An organic sodium salt that is the disodium salt of nitroprusside. FYPO_relaxed.owl CHEBI:38700 biolink:NamedThing organic sodium salt FYPO_relaxed.owl CHEBI:50011 biolink:NamedThing Calcofluor White FYPO_relaxed.owl CHEBI:64103 biolink:NamedThing sodium butyrate An organic sodium salt resulting from the replacement of the proton from the carboxy group of butyric acid by a sodium ion. FYPO_relaxed.owl CHEBI:87192 biolink:NamedThing phloxine B An organic sodium salt that is the disodium salt of 2,3,4,5-tetrachloro-6-(2,4,5,7-tetrabromo-6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid. It is used in the hematoxylin phloxine saffron (HPS) stain, stains paneth cell granules in Lendrum's phloxine-tartrazine method, and can be used to demonstrate alcoholic hyaline. FYPO_relaxed.owl CHEBI:8984 biolink:NamedThing sodium dodecyl sulfate An organic sodium salt that is the sodium salt of dodecyl hydrogen sulfate. FYPO_relaxed.owl CHEBI:29369 biolink:NamedThing peroxy group FYPO_relaxed.owl CHEBI:33246 biolink:NamedThing inorganic group Any substituent group which does not contain carbon. FYPO_relaxed.owl CHEBI:29785 biolink:NamedThing nitro group FYPO_relaxed.owl CHEBI:29792 biolink:NamedThing hydroperoxy group FYPO_relaxed.owl CHEBI:29917 biolink:NamedThing thiol group FYPO_relaxed.owl CHEBI:29922 biolink:NamedThing sulfo group FYPO_relaxed.owl CHEBI:30106 biolink:NamedThing azo group FYPO_relaxed.owl CHEBI:35801 biolink:NamedThing nitroso group FYPO_relaxed.owl CHEBI:43176 biolink:NamedThing hydroxy group FYPO_relaxed.owl CHEBI:46629 biolink:NamedThing oxo group FYPO_relaxed.owl CHEBI:3259 biolink:NamedThing CCCP A member of the class of monochlorobenzenes that is benzene substituted by 2-(1,3-dinitrilopropan-2-ylidene)hydrazinyl and chloro groups at positions 1 and 3, respectively. It is a mitochondrial depolarizing agent that induces reactive oxygen species mediated cell death. FYPO_relaxed.owl CHEBI:3764 biolink:NamedThing clotrimazole A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to a nitrogen is replaced by a monochlorotrityl group. FYPO_relaxed.owl CHEBI:35843 biolink:NamedThing arsine oxides H3As=O and its hydrocarbyl derivatives. FYPO_relaxed.owl CHEBI:29699 biolink:NamedThing tunicamycin A mixture of antiviral nucleoside antibiotics produced by Streptomyces lysosuperificus. It contains at least 10 homologues comprising uracil, N-acetylglucosamine, an 11-carbon aminodialdose called tunicamine, and a fatty acid linked to the amino group of the tunicamine. The homologues vary in the composition of the fatty acid moiety. FYPO_relaxed.owl CHEBI:60004 biolink:NamedThing mixture A mixture is a chemical substance composed of multiple molecules, at least two of which are of a different kind. FYPO_relaxed.owl CHEBI:75044 biolink:NamedThing phleomycin A mixture of glycopeptide antibiotics originally isolated from the bacterium Streptomyces verticillus whose components all contain a thiazolinylthiazole moiety and can form complexes with redox-active metals such as Co, Cu, and Fe. (Bleomycins are very similar to phleomycins, but have a bithiazole moiety in place of the thiazolinylthiazole moiety). FYPO_relaxed.owl CHEBI:76359 biolink:NamedThing butylated hydroxyanisole A mixture of 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole. Is is used as an antioxidant and preservative in food, cosmetics, pharmaceuticals, rubber and petroleum products. FYPO_relaxed.owl CHEBI:83630 biolink:NamedThing essential oil A mixture that is a concentrated hydrophobic liquid containing volatile aroma compounds obtained from plants, commonly by distillation (particularly steam distillation), but also by solvent extraction, or by crushing of seeds or fruits in a press. FYPO_relaxed.owl CHEBI:51144 biolink:NamedThing nitrogen group FYPO_relaxed.owl CHEBI:29986 biolink:NamedThing D-glutamate(1-) An alpha-amino-acid anion that is the conjugate base of D-glutamic acid, having anionic carboxy groups and a cationic amino group FYPO_relaxed.owl CHEBI:29988 biolink:NamedThing L-glutamate(2-) An L-alpha-amino acid anion that is the dianion obtained by the deprotonation of the both the carboxy groups of L-glutamic acid. FYPO_relaxed.owl CHEBI:29989 biolink:NamedThing D-glutamate(2-) FYPO_relaxed.owl CHEBI:29993 biolink:NamedThing L-aspartate(2-) An aspartate(2-) that is the conjugate base of L-aspartate(1-). FYPO_relaxed.owl CHEBI:32431 biolink:NamedThing L-alaninate The L-enantiomer of alaninate. FYPO_relaxed.owl CHEBI:32442 biolink:NamedThing L-cysteinate(1-) The L-enantiomer of cysteinate(1-). FYPO_relaxed.owl CHEBI:32486 biolink:NamedThing L-phenylalaninate An optically active form of phenylalaninate having L-configuration. FYPO_relaxed.owl CHEBI:32550 biolink:NamedThing L-lysinate An optically active form of lysinate having L-configuration. FYPO_relaxed.owl CHEBI:32604 biolink:NamedThing L-isoleucinate The L-enantiomer of isoleucinate. FYPO_relaxed.owl CHEBI:32619 biolink:NamedThing L-leucinate The L-enantiomer of leucinate. FYPO_relaxed.owl CHEBI:32650 biolink:NamedThing L-asparaginate An optically active form of asparaginate having L-configuration. FYPO_relaxed.owl CHEBI:32665 biolink:NamedThing L-glutaminate An optically active form of glutaminate having L-configuration. FYPO_relaxed.owl CHEBI:32681 biolink:NamedThing L-argininate An L-alpha-amino acid anion that is the conjugate base of L-arginine; obtained by deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32702 biolink:NamedThing L-tryptophanate The L-enantiomer of tryptophanate. FYPO_relaxed.owl CHEBI:32760 biolink:NamedThing L-tyrosinate(1-) An optically active form of tyrosinate having L-configuration. FYPO_relaxed.owl CHEBI:32820 biolink:NamedThing L-threoninate An L-alpha-amino acid anion that is the conjugate base of L-threonine, arising from deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32836 biolink:NamedThing L-serinate A serinate that is the conjugate base of L-serine, obtained by deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:32851 biolink:NamedThing L-valinate The L-enantiomer of valinate. FYPO_relaxed.owl CHEBI:32862 biolink:NamedThing L-prolinate An optically active form of prolinate having L-configuration. FYPO_relaxed.owl CHEBI:46914 biolink:NamedThing L-ornithinate An L-alpha-amino acid anion that is the conjugate base of L-ornithine. FYPO_relaxed.owl CHEBI:67009 biolink:NamedThing S-adenosyl-L-homocysteinate A L-alpha-amino acid anion obtained by deprotonation of S-adenosyl-L-homocysteine. FYPO_relaxed.owl CHEBI:29990 biolink:NamedThing D-aspartate(1-) An aspartate(1-) that is the conjugate base of D-aspartic acid. FYPO_relaxed.owl CHEBI:35391 biolink:NamedThing aspartate(1-) An alpha-amino-acid anion that is the conjugate base of aspartic acid. FYPO_relaxed.owl CHEBI:29995 biolink:NamedThing aspartate(2-) A C4-dicarboxylate that is the dianion obtained by the deprotonation of both the carboxy groups of aspartic acid. FYPO_relaxed.owl CHEBI:29994 biolink:NamedThing D-aspartate(2-) An aspartate(2-) that is the conjugate base of D-aspartate(1-). FYPO_relaxed.owl CHEBI:30031 biolink:NamedThing succinate(2-) A dicarboxylic acid dianion resulting from the removal of a proton from both of the carboxy groups of succinic acid. FYPO_relaxed.owl CHEBI:36180 biolink:NamedThing butenedioate FYPO_relaxed.owl CHEBI:30779 biolink:NamedThing succinate(1-) A dicarboxylic acid monoanion resulting from the removal of a proton from one of the carboxy groups of succinic acid. FYPO_relaxed.owl CHEBI:30087 biolink:NamedThing guanidinium FYPO_relaxed.owl CHEBI:60251 biolink:NamedThing guanidinium ion R = C or H. The iminium ion resulting from the protonation of one of the imine nitrogens of guanidine or its derivatives. FYPO_relaxed.owl CHEBI:84339 biolink:NamedThing synthalin A(2+) FYPO_relaxed.owl CHEBI:3392 biolink:NamedThing carbendazim A member of the class of benzimidazoles that is 2-aminobenzimidazole in which the primary amino group is substituted by a methoxycarbonyl group. A fungicide, carbendazim controls Ascomycetes, Fungi Imperfecti, and Basidiomycetes on a wide variety of crops, including bananas, cereals, cotton, fruits, grapes, mushrooms, ornamentals, peanuts, sugarbeet, soybeans, tobacco, and vegetables. FYPO_relaxed.owl CHEBI:30347 biolink:NamedThing ethylenediamine An alkane-alpha,omega-diamine in which the alkane is ethane. FYPO_relaxed.owl CHEBI:35411 biolink:NamedThing alkane-alpha,omega-diamine A primary diamine that is ethane or a higher alkane in which a hydrogen of each of the terminal methyl groups has been replaced by an amino group. H2NCH2(CH2)nCH2NH2, where n = 0, 1, 2, etc. FYPO_relaxed.owl CHEBI:30351 biolink:NamedThing 2,2'-bipyridine A bipyridine in which the two pyridine moieties are linked by a bond between positions C-2 and C-2'. FYPO_relaxed.owl CHEBI:35545 biolink:NamedThing bipyridine FYPO_relaxed.owl CHEBI:30985 biolink:NamedThing 4,4'-bipyridine A bipyridine in which the two pyridine moieties are linked by a bond between positions C-4 and C-4'. FYPO_relaxed.owl CHEBI:41808 biolink:NamedThing decane A straight-chain alkane with 10 carbon atoms. FYPO_relaxed.owl CHEBI:83563 biolink:NamedThing long-chain alkane Any alkane having a chain length of at least 13 carbon atoms. FYPO_relaxed.owl CHEBI:30413 biolink:NamedThing heme A heme is any tetrapyrrolic chelate of iron. FYPO_relaxed.owl CHEBI:33892 biolink:NamedThing iron coordination entity FYPO_relaxed.owl CHEBI:7596 biolink:NamedThing nitroprusside FYPO_relaxed.owl CHEBI:30465 biolink:NamedThing tellurous acid FYPO_relaxed.owl CHEBI:33519 biolink:NamedThing tellurium oxoacid FYPO_relaxed.owl CHEBI:30477 biolink:NamedThing tellurite FYPO_relaxed.owl CHEBI:33520 biolink:NamedThing tellurium oxoanion FYPO_relaxed.owl CHEBI:4735 biolink:NamedThing ethylenediaminetetraacetic acid FYPO_relaxed.owl CHEBI:46786 biolink:NamedThing diether A polyether in which the number of ether linkages is 2. FYPO_relaxed.owl CHEBI:39417 biolink:NamedThing branched-chain saturated fatty acid Any saturated fatty acid with a carbon side-chain or isopropyl termination. FYPO_relaxed.owl CHEBI:30916 biolink:NamedThing 2-oxoglutarate(1-) A dicarboxylic acid monoanion resulting from selective deprotonation of the 1-carboxy group of 2-oxoglutaric acid. FYPO_relaxed.owl CHEBI:30920 biolink:NamedThing 3-hydroxy-3-methylglutarate(1-) A dicarboxylic acid monoanion resulting from the removal of a proton from one of the carboxylic acid groups of 3-hydroxy-3-methylglutaric acid. FYPO_relaxed.owl CHEBI:35907 biolink:NamedThing glutarate(1-) A dicarboxylic acid monoanion that is the conjugate base of glutaric acid. FYPO_relaxed.owl CHEBI:37155 biolink:NamedThing hydrogen butenedioate FYPO_relaxed.owl CHEBI:50680 biolink:NamedThing methotrexate(1-) FYPO_relaxed.owl CHEBI:30780 biolink:NamedThing maleate(2-) A C4-dicarboxylate that is the Z-isomer of but-2-enedioate(2-) FYPO_relaxed.owl CHEBI:37156 biolink:NamedThing maleate(1-) A hydrogen butenedioate that is the conjugate base of maleic acid. FYPO_relaxed.owl CHEBI:30816 biolink:NamedThing vanillic acid A monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3. FYPO_relaxed.owl CHEBI:30823 biolink:NamedThing oleate A C18, long straight-chain monounsaturated fatty acid anion; and the conjugate base of oleic acid, arising from deprotonation of the carboxylic acid group. FYPO_relaxed.owl CHEBI:30911 biolink:NamedThing glucitol FYPO_relaxed.owl CHEBI:30915 biolink:NamedThing 2-oxoglutaric acid An oxo dicarboxylic acid that consists of glutaric acid bearing an oxo substituent at position 2. It is an intermediate metabolite in Krebs cycle. FYPO_relaxed.owl CHEBI:78128 biolink:NamedThing fatty acid anion 24:0 Any saturated fatty acid anion containing 24 carbons. Formed by deprotonation of the carboxylic acid moiety. Major species at pH 7.3. FYPO_relaxed.owl CHEBI:31669 biolink:NamedThing hexestrol FYPO_relaxed.owl CHEBI:31941 biolink:NamedThing oxaliplatin A platinum coordination entity that is a commonly used chemothrepeutic drug for treatment of colorectal cancer. FYPO_relaxed.owl CHEBI:33862 biolink:NamedThing platinum coordination entity FYPO_relaxed.owl CHEBI:85609 biolink:NamedThing satraplatin A platinum coordination entity that consists of a central platunum atom bound to chloro (x2), acetate (x2), amino, and cyclohexylamino groups. Used for treatment of advanced prostate cancer. FYPO_relaxed.owl CHEBI:85610 biolink:NamedThing JM335 A platinum coordination entity that consists of a central platinum atom bound to chloro (x2), hydroxy (x2), amino, and cyclohexylamino groups. FYPO_relaxed.owl CHEBI:85611 biolink:NamedThing triplatin tetranitrate A trinuclear platinum coordination entity that is the tetranitrate salt of triplatin. FYPO_relaxed.owl CHEBI:32435 biolink:NamedThing D-alaninate The D-enantiomer of alaninate. FYPO_relaxed.owl CHEBI:32432 biolink:NamedThing L-alaninium The L-enantiomer of alaninium. FYPO_relaxed.owl CHEBI:32436 biolink:NamedThing D-alaninium An alaninium that is the conjugate acid of D-alanine. FYPO_relaxed.owl CHEBI:32449 biolink:NamedThing D-cysteinate(1-) The D-enantiomer of cysteinate(1-). FYPO_relaxed.owl CHEBI:32443 biolink:NamedThing L-cysteinate(2-) The L-enantiomer of cysteinate(2-). FYPO_relaxed.owl CHEBI:32450 biolink:NamedThing D-cysteinate(2-) The D-enantiomer of cysteinate(2-). FYPO_relaxed.owl CHEBI:32445 biolink:NamedThing L-cysteinium The L-enantiomer of cysteinium. FYPO_relaxed.owl CHEBI:32451 biolink:NamedThing D-cysteinium The D-enantiomer of cysteinium. FYPO_relaxed.owl CHEBI:32494 biolink:NamedThing D-phenylalaninate The D-enantiomer of phenylalaninate. FYPO_relaxed.owl CHEBI:32487 biolink:NamedThing L-phenylalaninium An optically active form of phenylalaninium having L-configuration. FYPO_relaxed.owl CHEBI:32495 biolink:NamedThing D-phenylalaninium An optically active form of phenylalaninium having D-configuration. FYPO_relaxed.owl CHEBI:32496 biolink:NamedThing L-phenylalanyl group FYPO_relaxed.owl CHEBI:32500 biolink:NamedThing D-phenylalanyl group FYPO_relaxed.owl CHEBI:33716 biolink:NamedThing N-terminal proteinogenic amino-acid residue FYPO_relaxed.owl CHEBI:32510 biolink:NamedThing L-histidinate(1-) The L-enantiomer of histidinate(1-), FYPO_relaxed.owl CHEBI:32523 biolink:NamedThing D-histidinate(1-) The D-enantiomer of histidinate(1-). FYPO_relaxed.owl CHEBI:32511 biolink:NamedThing L-histidinate(2-) The L-enantiomer of histidinate(2-). FYPO_relaxed.owl CHEBI:32524 biolink:NamedThing D-histidinate(2-) The D-enantiomer of histidinate(2-). FYPO_relaxed.owl CHEBI:32512 biolink:NamedThing L-histidinium(2+) The L-enantiomer of histidinium(2+). FYPO_relaxed.owl CHEBI:32527 biolink:NamedThing D-histidinium(2+) The D-enantiomer of histidinium(2+). FYPO_relaxed.owl CHEBI:32513 biolink:NamedThing L-histidinium(1+) The L-enantiomer of histidinium(1+). FYPO_relaxed.owl CHEBI:32526 biolink:NamedThing D-histidinium(1+) The D-enantiomer of histidinium(1+). FYPO_relaxed.owl CHEBI:32556 biolink:NamedThing D-lysinate An optically active form of lysinate having D-configuration. FYPO_relaxed.owl CHEBI:32557 biolink:NamedThing D-lysinium(1+) An optically active form of lysinium having D-configuration. FYPO_relaxed.owl CHEBI:32552 biolink:NamedThing L-lysinium(2+) The L-enantiomer of lysinium(2+). FYPO_relaxed.owl CHEBI:32558 biolink:NamedThing D-lysinium(2+) The D-enantiomer of lysinium(2+). FYPO_relaxed.owl CHEBI:33189 biolink:NamedThing hydrazonomalononitrile FYPO_relaxed.owl CHEBI:51308 biolink:NamedThing dinitrile A dinitrile is a compound containing two nitrile groups. FYPO_relaxed.owl CHEBI:80291 biolink:NamedThing aliphatic nitrile Any nitrile derived from an aliphatic compound. FYPO_relaxed.owl CHEBI:32600 biolink:NamedThing tetracene An acene that consists of four ortho-fused benzene rings in a rectilinear arrangement. FYPO_relaxed.owl CHEBI:35297 biolink:NamedThing acene A polycyclic aromatic hydrocarbon consisting of fused benzene rings in a rectilinear arrangement. FYPO_relaxed.owl CHEBI:51270 biolink:NamedThing tetracenes Compounds containing a tetracene skeleton. FYPO_relaxed.owl CHEBI:32608 biolink:NamedThing D-isoleucinate The D-enantiomer of isoleucinate. FYPO_relaxed.owl CHEBI:32605 biolink:NamedThing L-isoleucinium The L-enantiomer of isoleucinium. FYPO_relaxed.owl CHEBI:32609 biolink:NamedThing D-isoleucinium The D-enantiomer of isoleucinium. FYPO_relaxed.owl CHEBI:32623 biolink:NamedThing D-leucinate The D-enantiomer of leucinate. FYPO_relaxed.owl CHEBI:32620 biolink:NamedThing L-leucinium The L-enantiomer of leucinium. FYPO_relaxed.owl CHEBI:32624 biolink:NamedThing D-leucinium The D-enantiomer of leucinium. FYPO_relaxed.owl CHEBI:32631 biolink:NamedThing L-methioninate The L-enantiomer of methioninate. FYPO_relaxed.owl CHEBI:32637 biolink:NamedThing D-methioninate The D-enantiomer of methioninate. FYPO_relaxed.owl CHEBI:32632 biolink:NamedThing L-methioninium The L-enantiomer of methioninium. FYPO_relaxed.owl CHEBI:32638 biolink:NamedThing D-methioninium The D-enantiomer of methioninium. FYPO_relaxed.owl CHEBI:32656 biolink:NamedThing D-asparaginate FYPO_relaxed.owl CHEBI:32651 biolink:NamedThing L-asparaginium FYPO_relaxed.owl CHEBI:32657 biolink:NamedThing D-asparaginium FYPO_relaxed.owl CHEBI:32664 biolink:NamedThing asparagine residue FYPO_relaxed.owl CHEBI:33710 biolink:NamedThing alpha-amino-acid residue FYPO_relaxed.owl CHEBI:33700 biolink:NamedThing proteinogenic amino-acid residue FYPO_relaxed.owl CHEBI:33715 biolink:NamedThing N-terminal alpha-amino-acid residue FYPO_relaxed.owl CHEBI:32672 biolink:NamedThing D-glutaminate An optically active form of glutaminate having D-configuration. FYPO_relaxed.owl CHEBI:32666 biolink:NamedThing L-glutaminium An optically active form of glutaminium having L-configuration. FYPO_relaxed.owl CHEBI:32673 biolink:NamedThing D-glutaminium An optically active form of glutaminium having D-configuration. FYPO_relaxed.owl CHEBI:32688 biolink:NamedThing D-argininate FYPO_relaxed.owl CHEBI:32682 biolink:NamedThing L-argininium(1+) The L-enantiomer of argininium(1+). FYPO_relaxed.owl CHEBI:32689 biolink:NamedThing D-argininium(1+) The D-enantiomer of argininium(1+). FYPO_relaxed.owl CHEBI:32683 biolink:NamedThing L-argininium(2+) FYPO_relaxed.owl CHEBI:32690 biolink:NamedThing D-argininium(2+) FYPO_relaxed.owl CHEBI:32716 biolink:NamedThing D-tryptophanate The D-enantiomer of tryptophanate. FYPO_relaxed.owl CHEBI:32704 biolink:NamedThing L-tryptophanium The L-enantiomer of tryptophanium. FYPO_relaxed.owl CHEBI:32717 biolink:NamedThing D-tryptophanium The D-enantiomer of tryptophanium. FYPO_relaxed.owl CHEBI:32773 biolink:NamedThing D-tyrosinate(1-) An optically active form of tyrosinate(1-) having D-configuration. FYPO_relaxed.owl CHEBI:32761 biolink:NamedThing L-tyrosinate(2-) The L-enantiomer of tyrosinate(2-). FYPO_relaxed.owl CHEBI:32774 biolink:NamedThing D-tyrosinate(2-) The D-enantiomer of tyrosinate(2-). FYPO_relaxed.owl CHEBI:32762 biolink:NamedThing L-tyrosinium An optically active form of tyrosinium having L-configuration. FYPO_relaxed.owl CHEBI:32775 biolink:NamedThing D-tyrosinium An optically active form of tyrosinium having D-configuration. FYPO_relaxed.owl CHEBI:32805 biolink:NamedThing cis-aconitic acid The cis-isomer of aconitic acid. FYPO_relaxed.owl CHEBI:32827 biolink:NamedThing D-threoninate The D-enantiomer of threoninate. FYPO_relaxed.owl CHEBI:32822 biolink:NamedThing L-threoninium The L-enantiomer of threoninium. FYPO_relaxed.owl CHEBI:32828 biolink:NamedThing D-threoninium The D-enantiomer of threoninium. FYPO_relaxed.owl CHEBI:32840 biolink:NamedThing D-serinate The D-enantiomer of serinate. FYPO_relaxed.owl CHEBI:32837 biolink:NamedThing L-serinium A serinium that is the conjugate acid of L-serine, obtained by protonation of the amino group. FYPO_relaxed.owl CHEBI:32841 biolink:NamedThing D-serinium The D-enantiomer of serinium. FYPO_relaxed.owl CHEBI:32855 biolink:NamedThing D-valinate The D-enantiomer of valinate. FYPO_relaxed.owl CHEBI:32852 biolink:NamedThing L-valinium The L-enantiomer of valinium. FYPO_relaxed.owl CHEBI:32856 biolink:NamedThing D-valinium The D-enantiomer of valinium. FYPO_relaxed.owl CHEBI:32867 biolink:NamedThing D-prolinate An optically active form of prolinate having D-configuration. FYPO_relaxed.owl CHEBI:32864 biolink:NamedThing L-prolinium An optically active form of prolinium having L-configuration. FYPO_relaxed.owl CHEBI:32868 biolink:NamedThing D-prolinium An optically active form of prolinium having D-configuration. FYPO_relaxed.owl CHEBI:40235 biolink:NamedThing 9H-purine-2,6-diamine A member of the class of 2,6-diaminopurines that is 9H-purine in which the hydrogens at positions 2 and 6 are replaced by amino groups. FYPO_relaxed.owl CHEBI:32878 biolink:NamedThing alkene An acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n. Acyclic branched or unbranched hydrocarbons having more than one double bond are alkadienes, alkatrienes, etc. FYPO_relaxed.owl CHEBI:33645 biolink:NamedThing acyclic olefin Acyclic branched or unbranched hydrocarbons having one or more carbon-carbon double bond. FYPO_relaxed.owl CHEBI:32926 biolink:NamedThing octadecane A straight-chain alkane carrying 18 carbon atoms. FYPO_relaxed.owl CHEBI:33007 biolink:NamedThing chromium(6+) FYPO_relaxed.owl CHEBI:33423 biolink:NamedThing monoatomic hexacation FYPO_relaxed.owl CHEBI:33145 biolink:NamedThing boron oxoacid FYPO_relaxed.owl CHEBI:33484 biolink:NamedThing chalcogen oxoacid FYPO_relaxed.owl CHEBI:33173 biolink:NamedThing benzimidazolide FYPO_relaxed.owl CHEBI:33186 biolink:NamedThing malononitrile A dinitrile that is methane substituted by two cyano groups. FYPO_relaxed.owl CHEBI:33187 biolink:NamedThing oxomalononitrile FYPO_relaxed.owl CHEBI:51852 biolink:NamedThing alpha-ketonitrile A ketonitrile where the ketone and nitrile functionalities are on adjacent atoms. FYPO_relaxed.owl CHEBI:33198 biolink:NamedThing D-gluconic acid A gluconic acid having D-configuration. FYPO_relaxed.owl CHEBI:86359 biolink:NamedThing L-gluconic acid A gluconic acid having L-configuration. FYPO_relaxed.owl CHEBI:33216 biolink:NamedThing bisphenol A A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups. FYPO_relaxed.owl CHEBI:33233 biolink:NamedThing fundamental particle A particle not known to have substructure. FYPO_relaxed.owl CHEBI:36342 biolink:NamedThing subatomic particle A particle smaller than an atom. FYPO_relaxed.owl CHEBI:36340 biolink:NamedThing fermion Particle of half-integer spin quantum number following Fermi-Dirac statistics. Fermions are named after Enrico Fermi. FYPO_relaxed.owl CHEBI:36343 biolink:NamedThing composite particle A subatomic particle known to have substructure (i.e. consisting of smaller particles). FYPO_relaxed.owl CHEBI:36347 biolink:NamedThing nuclear particle A nucleus or any of its constituents in any of their energy states. FYPO_relaxed.owl CHEBI:33434 biolink:NamedThing elemental halogen FYPO_relaxed.owl CHEBI:85541 biolink:NamedThing elemental bismuth FYPO_relaxed.owl CHEBI:37175 biolink:NamedThing organic hydride FYPO_relaxed.owl CHEBI:36823 biolink:NamedThing pseudohalo group FYPO_relaxed.owl CHEBI:64766 biolink:NamedThing cationic group A group that carries an overall positive charge. FYPO_relaxed.owl CHEBI:33249 biolink:NamedThing organyl group Any organic substituent group, regardless of functional type, having one free valence at a carbon atom. FYPO_relaxed.owl CHEBI:46883 biolink:NamedThing carboxy group FYPO_relaxed.owl CHEBI:33252 biolink:NamedThing atomic nucleus A nucleus is the positively charged central portion of an atom, excluding the orbital electrons. FYPO_relaxed.owl CHEBI:33253 biolink:NamedThing nucleon Heavy nuclear particle: proton or neutron. FYPO_relaxed.owl CHEBI:36339 biolink:NamedThing baryon Baryon is a fermion that does experience the strong force (strong interaction). The term is derived from the Greek betaalpharhoupsilonsigma (heavy). FYPO_relaxed.owl CHEBI:78295 biolink:NamedThing food component A physiological role played by any substance that is distributed in foodstuffs. It includes materials derived from plants or animals, such as vitamins or minerals, as well as environmental contaminants. FYPO_relaxed.owl CHEBI:33287 biolink:NamedThing fertilizer A fertilizer is any substance that is added to soil or water to assist the growth of plants. FYPO_relaxed.owl CHEBI:86328 biolink:NamedThing antifungal agrochemical Any substance used in acriculture, horticulture, forestry, etc. for its fungicidal properties. FYPO_relaxed.owl CHEBI:33561 biolink:NamedThing d-block element atom FYPO_relaxed.owl CHEBI:33362 biolink:NamedThing nickel group element atom FYPO_relaxed.owl CHEBI:33364 biolink:NamedThing platinum FYPO_relaxed.owl CHEBI:33365 biolink:NamedThing platinum group metal atom FYPO_relaxed.owl CHEBI:33384 biolink:NamedThing L-serine zwitterion A serine zwitterion obtained by transfer of a proton from the carboxy to the amino group of L-serine. FYPO_relaxed.owl CHEBI:35243 biolink:NamedThing serine zwitterion An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of serine. FYPO_relaxed.owl CHEBI:35247 biolink:NamedThing D-serine zwitterion A serine zwitterion obtained by transfer of a proton from the carboxy to the amino group of D-serine. FYPO_relaxed.owl CHEBI:33457 biolink:NamedThing phosphorus oxoacid A pnictogen oxoacid which contains phosphorus and oxygen, at least one hydrogen atom bound to oxygen, and forms an ion by the loss of one or more protons. FYPO_relaxed.owl CHEBI:36829 biolink:NamedThing polyatomic monoanion FYPO_relaxed.owl CHEBI:36892 biolink:NamedThing elemental fluorine FYPO_relaxed.owl CHEBI:36894 biolink:NamedThing elemental bromine FYPO_relaxed.owl CHEBI:39124 biolink:NamedThing calcium ion FYPO_relaxed.owl CHEBI:60252 biolink:NamedThing lead cation A lead atom having a positive net electric charge. FYPO_relaxed.owl CHEBI:63062 biolink:NamedThing aluminium cation An aluminium atom having a positive net electric charge. FYPO_relaxed.owl CHEBI:33508 biolink:NamedThing glyceric acid A trionic acid that consists of propionic acid substituted at positions 2 and 3 by hydroxy groups. FYPO_relaxed.owl CHEBI:33754 biolink:NamedThing trionic acid FYPO_relaxed.owl CHEBI:33552 biolink:NamedThing sulfonic acid derivative FYPO_relaxed.owl CHEBI:33555 biolink:NamedThing arenesulfonic acid Organic derivatives of sulfonic acid in which the sulfo group is linked directly to carbon of an aryl group. FYPO_relaxed.owl CHEBI:50010 biolink:NamedThing 4,4'-bis({4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino)stilbene-2,2'-disulfonic acid An organosulfonic acid comprising stilbene having 4-anilino-6-[bis(2-hydroxyethyl)amino]-1,3,5-triazin-2-yl}amino groups at the 4 and 4'-positions and sulfo groups at the 2- and 2'-positions. FYPO_relaxed.owl CHEBI:33566 biolink:NamedThing catechols Any compound containing an o-diphenol component. FYPO_relaxed.owl CHEBI:33595 biolink:NamedThing cyclic compound Any molecule that consists of a series of atoms joined together to form a ring. FYPO_relaxed.owl CHEBI:33597 biolink:NamedThing homocyclic compound A cyclic compound having as ring members atoms of the same element only. FYPO_relaxed.owl CHEBI:33635 biolink:NamedThing polycyclic compound FYPO_relaxed.owl CHEBI:33636 biolink:NamedThing bicyclic compound A molecule that features two fused rings. FYPO_relaxed.owl CHEBI:33655 biolink:NamedThing aromatic compound A cyclically conjugated molecular entity with a stability (due to delocalization) significantly greater than that of a hypothetical localized structure (e.g. Kekule structure) is said to possess aromatic character. FYPO_relaxed.owl CHEBI:33661 biolink:NamedThing monocyclic compound FYPO_relaxed.owl CHEBI:36820 biolink:NamedThing ring assembly Two or more cyclic systems (single rings or fused systems) which are directly joined to each other by double or single bonds are named ring assemblies when the number of such direct ring junctions is one less than the number of cyclic systems involved. FYPO_relaxed.owl CHEBI:35295 biolink:NamedThing homopolycyclic compound FYPO_relaxed.owl CHEBI:33599 biolink:NamedThing spiro compound A compound having one atom as the only common member of two rings. FYPO_relaxed.owl CHEBI:35293 biolink:NamedThing fused compound FYPO_relaxed.owl CHEBI:35990 biolink:NamedThing bridged compound A polycyclic compound in which two rings have two or more atoms in common. FYPO_relaxed.owl CHEBI:33637 biolink:NamedThing ortho-fused compound A polycyclic compound in which two rings have two, and only two, atoms in common. Such compounds have n common faces and 2n common atoms. FYPO_relaxed.owl CHEBI:33642 biolink:NamedThing cyclic olefin The inclusive term for any cyclic hydrocarbon having any number of double bonds. FYPO_relaxed.owl CHEBI:48121 biolink:NamedThing polyene An olefin that contains more than one carbon-carbon double bond. FYPO_relaxed.owl CHEBI:35294 biolink:NamedThing carbopolycyclic compound A polyclic compound in which all of the ring members are carbon atoms. FYPO_relaxed.owl CHEBI:49319 biolink:NamedThing carbocyclic antibiotic FYPO_relaxed.owl CHEBI:33664 biolink:NamedThing monocyclic hydrocarbon FYPO_relaxed.owl CHEBI:33666 biolink:NamedThing polycyclic hydrocarbon FYPO_relaxed.owl CHEBI:33662 biolink:NamedThing annulene A mancude monocyclic hydrocarbon without side chains of the general formula CnHn (n is an even number) or CnHn+1 (n is an odd number). In systematic nomenclature an annulene with seven or more carbon atoms may be named [n]annulene, where n is the number of carbon atoms. FYPO_relaxed.owl CHEBI:33676 biolink:NamedThing d-block molecular entity A d-block molecular entity is a molecular entity containing one or more atoms of a d-block element. FYPO_relaxed.owl CHEBI:33747 biolink:NamedThing nickel group molecular entity FYPO_relaxed.owl CHEBI:33703 biolink:NamedThing amino-acid cation FYPO_relaxed.owl CHEBI:33712 biolink:NamedThing N-terminal amino-acid residue The residue in a peptide that has an amino group that is free, or at least not acylated by another amino-acid residue, is called N-terminal. FYPO_relaxed.owl PR:000025513 biolink:NamedThing modified amino-acid residue An organic group that results from covalent modification or chemical alteration to the side chain or backbone atoms of an amino acid residue or derivative thereof, where such alteration maintains the integrity of the amino acid chain containing the residue. FYPO_relaxed.owl CHEBI:33749 biolink:NamedThing platinum molecular entity FYPO_relaxed.owl CHEBI:33755 biolink:NamedThing tetronic acid FYPO_relaxed.owl CHEBI:33760 biolink:NamedThing hexonate FYPO_relaxed.owl CHEBI:33791 biolink:NamedThing canonical nucleoside residue FYPO_relaxed.owl CHEBI:33792 biolink:NamedThing canonical ribonucleoside residue FYPO_relaxed.owl CHEBI:33793 biolink:NamedThing canonical deoxyribonucleoside residue FYPO_relaxed.owl CHEBI:47017 biolink:NamedThing tetrahydrofuranol FYPO_relaxed.owl CHEBI:338412 biolink:NamedThing (-)-anisomycin An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system. FYPO_relaxed.owl CHEBI:46777 biolink:NamedThing monohydroxypyrrolidine FYPO_relaxed.owl CHEBI:33847 biolink:NamedThing monocyclic arene A monocyclic aromatic hydrocarbon. FYPO_relaxed.owl CHEBI:33848 biolink:NamedThing polycyclic arene A polycyclic aromatic hydrocarbon. FYPO_relaxed.owl CHEBI:33966 biolink:NamedThing elemental silver FYPO_relaxed.owl CHEBI:33973 biolink:NamedThing elemental magnesium FYPO_relaxed.owl CHEBI:33975 biolink:NamedThing magnesium salt FYPO_relaxed.owl CHEBI:33976 biolink:NamedThing magnesium coordination entity FYPO_relaxed.owl CHEBI:34653 biolink:NamedThing Congo Red An indicator dye that is blue-violet at pH 3.0 and red at pH 5.0. FYPO_relaxed.owl CHEBI:48960 biolink:NamedThing bis(azo) compound Any azo compound containing two -N=N- groups. FYPO_relaxed.owl CHEBI:34656 biolink:NamedThing cumene An alkylbenzene that is benzene carrying an isopropyl group. FYPO_relaxed.owl CHEBI:34779 biolink:NamedThing glyoxal The dialdehyde that is the smallest possible and which consists of ethane having oxo groups on both carbons. FYPO_relaxed.owl CHEBI:87632 biolink:NamedThing statin (naturally occurring) Any statin that occurs in nature. The class includes compactin (also known as mevastatin), isolated from a fermentation broth of Penicillium citrinum, and lovastatin, isolated from Aspergillus terreus. FYPO_relaxed.owl CHEBI:35155 biolink:NamedThing elemental calcium FYPO_relaxed.owl CHEBI:35219 biolink:NamedThing plant growth retardant FYPO_relaxed.owl CHEBI:35235 biolink:NamedThing L-cysteine zwitterion FYPO_relaxed.owl CHEBI:35237 biolink:NamedThing cysteine zwitterion FYPO_relaxed.owl CHEBI:35236 biolink:NamedThing D-cysteine zwitterion FYPO_relaxed.owl CHEBI:35238 biolink:NamedThing amino acid zwitterion The zwitterionic form of an amino acid having a negatively charged carboxyl group and a positively charged amino group. FYPO_relaxed.owl CHEBI:405237 biolink:NamedThing L-canavanine zwitterion L-Canavanine in zwitterionic form. FYPO_relaxed.owl CHEBI:57305 biolink:NamedThing glycine zwitterion An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of glycine. FYPO_relaxed.owl CHEBI:57427 biolink:NamedThing L-leucine zwitterion Zwitterionic form of L-leucine. FYPO_relaxed.owl CHEBI:57476 biolink:NamedThing L-homoserine zwitterion Zwitterionic form of L-homoserine. FYPO_relaxed.owl CHEBI:57610 biolink:NamedThing N(alpha),N(alpha)-dimethyl-L-histidine zwitterion An amino acid zwitterion of N(alpha),N(alpha)-dimethyl-L-histidine having an anionic carboxy group and a protonated amino group. FYPO_relaxed.owl CHEBI:57743 biolink:NamedThing L-citrulline zwitterion Zwitterionic form of L-citrulline having an anionic carboxy group and a protonated amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57856 biolink:NamedThing S-adenosyl-L-homocysteine zwitterion Zwitterionic form of S-adenosyl-L-homocysteine arising from migration of a proton from the carboxy group to the alpha-amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57926 biolink:NamedThing L-threonine zwitterion Zwitterionic form of L-threonine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57966 biolink:NamedThing beta-alanine zwitterion Zwitterionic form of beta-alanine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58000 biolink:NamedThing D-glutamine zwitterion Zwitterionic form of D-glutamine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58048 biolink:NamedThing L-asparagine zwitterion Zwitterionic form of L-asparagine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58065 biolink:NamedThing homocysteine zwitterion An amino acid zwitterion of homocysteine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58095 biolink:NamedThing L-phenylalanine zwitterion An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of L-phenylalanine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58315 biolink:NamedThing L-tyrosine zwitterion An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of L-tyrosine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58717 biolink:NamedThing S-substituted L-cysteine zwitterion The zwitterionic form of an S-substituted L-cysteine. FYPO_relaxed.owl CHEBI:58773 biolink:NamedThing L-methionine (R)-S-oxide zwitterion Zwitterionic form of L-methionine (R)-S-oxide. FYPO_relaxed.owl CHEBI:60039 biolink:NamedThing L-proline zwitterion The zwitterion formed from L-proline by proton transfer from the carboxy group to the ring nitrogen. It is the predominant species at physiological pH. FYPO_relaxed.owl CHEBI:61512 biolink:NamedThing N(2)-acetyl-L-lysine zwitterion An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of N(2)-acetyl-L-lysine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:64554 biolink:NamedThing tryptophan zwitterion An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of tryptophan; major species at pH 7.3. FYPO_relaxed.owl CHEBI:64558 biolink:NamedThing methionine zwitterion An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of methionine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:66916 biolink:NamedThing alanine zwitterion An amino acid zwitterion arising from transfer of a proton from the carboxy to the amino group of alanine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:76042 biolink:NamedThing aromatic amino-acid zwitterion An amino acid zwitterion obtained by transfer of a proton from the carboxy to the amino group of any aromatic amino-acid. FYPO_relaxed.owl CHEBI:86139 biolink:NamedThing N-methyl-L-alpha-amino acid zwitterion An amino acid zwitterion obtained by transfer of a proton from the amino to the carboxy group of any N-methyl-L-alpha-amino acid; major species at pH 7.3. FYPO_relaxed.owl CHEBI:35281 biolink:NamedThing onium betaine Neutral molecules having charge-separated forms with an onium atom which bears no hydrogen atoms and that is not adjacent to the anionic atom. FYPO_relaxed.owl CHEBI:72823 biolink:NamedThing glycerophosphoethanolamine zwitterion A zwitterion obtained by transfer of a proton from the phosphate to the amino group of any glycerophosphoethanolamine. FYPO_relaxed.owl CHEBI:77932 biolink:NamedThing tetracycline zwitterion A zwitterion obtained by transfer of a proton from the 2-hydroxy group to the 1-amino group of tetracycline. It is the major microspecies at pH 7.3 (according to Marvin v 6.2.0.). FYPO_relaxed.owl CHEBI:35296 biolink:NamedThing ortho-fused polycyclic arene FYPO_relaxed.owl CHEBI:35427 biolink:NamedThing ortho-fused polycyclic hydrocarbon FYPO_relaxed.owl CHEBI:35337 biolink:NamedThing central nervous system stimulant Any drug that enhances the activity of the central nervous system. FYPO_relaxed.owl CHEBI:35471 biolink:NamedThing psychotropic drug A loosely defined grouping of drugs that have effects on psychological function. FYPO_relaxed.owl CHEBI:35488 biolink:NamedThing central nervous system depressant A loosely defined group of drugs that tend to reduce the activity of the central nervous system. FYPO_relaxed.owl CHEBI:35410 biolink:NamedThing primary diamine A primary diamine is a compound derived from a hydrocarbon by replacing two hydrogen atoms by amino groups. FYPO_relaxed.owl CHEBI:48218 biolink:NamedThing antiseptic drug A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body). FYPO_relaxed.owl CHEBI:35444 biolink:NamedThing antinematodal drug A substance used in the treatment or control of nematode infestations. FYPO_relaxed.owl CHEBI:35469 biolink:NamedThing antidepressant Antidepressants are mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. FYPO_relaxed.owl CHEBI:35473 biolink:NamedThing tranquilizing drug A traditional grouping of drugs said to have a soothing or calming effect on mood, thought or behaviour. FYPO_relaxed.owl CHEBI:35623 biolink:NamedThing anticonvulsant A drug used to prevent seizures or reduce their severity. FYPO_relaxed.owl CHEBI:35717 biolink:NamedThing sedative A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. FYPO_relaxed.owl CHEBI:35476 biolink:NamedThing antipsychotic agent Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. FYPO_relaxed.owl CHEBI:35477 biolink:NamedThing antimanic drug Antimanic drugs are agents used to treat bipolar disorders or mania associated with other affective disorders. FYPO_relaxed.owl CHEBI:60832 biolink:NamedThing tubulin modulator Any substance that interacts with tubulin to inhibit or promote polymerisation of microtubules. FYPO_relaxed.owl CHEBI:64911 biolink:NamedThing antimitotic Any compound that inhibits cell division (mitosis). FYPO_relaxed.owl CHEBI:35481 biolink:NamedThing non-narcotic analgesic A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors. FYPO_relaxed.owl CHEBI:35486 biolink:NamedThing maleate ester Compounds of the general formula ROOC-CH=CH-COOR' where R and R' are organyl groups FYPO_relaxed.owl CHEBI:35505 biolink:NamedThing hydrate An addition compound that contains water in weak chemical combination with another compound. FYPO_relaxed.owl CHEBI:35506 biolink:NamedThing alkaloid fundamental parent FYPO_relaxed.owl CHEBI:35550 biolink:NamedThing 1H-1,2,4-triazole FYPO_relaxed.owl CHEBI:35560 biolink:NamedThing 1,2,4-triazole FYPO_relaxed.owl CHEBI:35561 biolink:NamedThing 3H-1,2,4-triazole FYPO_relaxed.owl CHEBI:46077 biolink:NamedThing 4H-1,2,4-triazole FYPO_relaxed.owl CHEBI:35571 biolink:NamedThing mancude organic heterocyclic parent FYPO_relaxed.owl CHEBI:38597 biolink:NamedThing triazole FYPO_relaxed.owl CHEBI:36388 biolink:NamedThing saturated organic heterocyclic parent FYPO_relaxed.owl CHEBI:36624 biolink:NamedThing naphthyridine Any one of eight organic heterobicyclic compounds that have a naphthalene skeleton in which two of the carbons are replaced by nitrogens. A 'closed' class. FYPO_relaxed.owl CHEBI:35608 biolink:NamedThing EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor which interferes with the activity of the enzyme protein tyrosine phosphatases (PTPs), EC 3.1.3.48, involved in the removal of phosphate groups from phosphorylated tyrosine residues on proteins. FYPO_relaxed.owl CHEBI:76775 biolink:NamedThing EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of any phosphoric monoester hydrolase (EC 3.1.3.*). FYPO_relaxed.owl CHEBI:37153 biolink:NamedThing EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor Any EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of phosphoprotein phosphatase (EC 3.1.3.16). FYPO_relaxed.owl CHEBI:63332 biolink:NamedThing EC 3.1.3.1 (alkaline phosphatase) inhibitor An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of alkaline phosphatase (EC 3.1.3.1). FYPO_relaxed.owl CHEBI:77024 biolink:NamedThing EC 3.1.3.41 (4-nitrophenylphosphatase) inhibitor An EC 3.1.3.* (phosphoric monoester hydrolase) inhibitor that interferes with the action of 4-nitrophenylphosphatase (EC 3.1.3.41). FYPO_relaxed.owl CHEBI:35617 biolink:NamedThing flavouring agent A food additive that is used to added improve the taste or odour of a food. FYPO_relaxed.owl CHEBI:64049 biolink:NamedThing food acidity regulator A food additive that is used to change or otherwise control the acidity or alkalinity of foods. They may be acids, bases, neutralising agents or buffering agents. FYPO_relaxed.owl CHEBI:64577 biolink:NamedThing flour treatment agent A food additive which is added to flour or dough to improve baking quality and/or colour. FYPO_relaxed.owl CHEBI:65255 biolink:NamedThing food preservative Substances which are added to food in order to prevent decomposition caused by microbial growth or by undesirable chemical changes. FYPO_relaxed.owl CHEBI:77182 biolink:NamedThing food colouring A food additive that imparts colour to food. In European countries, E-numbers for permitted food colours are from E 100 to E 199, divided into yellows (E 100-109), oranges (E 110-119), reds (E 120-129), blues and violets (E 130-139), greens (E 140-149), browns and blacks (E 150-159), and others (E 160-199). FYPO_relaxed.owl CHEBI:78017 biolink:NamedThing food propellant A propellant that is used to expel foods from an aerosol container. FYPO_relaxed.owl CHEBI:46774 biolink:NamedThing polyether Any ether that contains more than one ether linkage. FYPO_relaxed.owl CHEBI:35704 biolink:NamedThing N(2)-acetyl-L-lysine An acetyl-L-lysine where the acetyl group is located at the N(2)-posiiton. FYPO_relaxed.owl CHEBI:35705 biolink:NamedThing immunosuppressive agent An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. FYPO_relaxed.owl CHEBI:50847 biolink:NamedThing immunological adjuvant A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity. FYPO_relaxed.owl CHEBI:38780 biolink:NamedThing N-nitro compound A compound having the nitro group (-NO2) attached to a nitrogen atom. FYPO_relaxed.owl CHEBI:35779 biolink:NamedThing dicarboxylic acid diamide FYPO_relaxed.owl CHEBI:35818 biolink:NamedThing coccidiostat An agent useful in the treatment or prevention of coccidiosis in man or animals. FYPO_relaxed.owl CHEBI:36335 biolink:NamedThing trypanocidal drug A drug used to treat or prevent infections caused by protozoal organisms belonging to the suborder Trypanosomatida. FYPO_relaxed.owl CHEBI:64915 biolink:NamedThing antiplasmodial drug An antiparasitic drug which is effective against Apicomplexan parasites in the genus Plasmodium. The genus contains over 200 species and includes those responsible for malaria. FYPO_relaxed.owl CHEBI:36047 biolink:NamedThing antibacterial drug A drug used to treat or prevent bacterial infections. FYPO_relaxed.owl CHEBI:35821 biolink:NamedThing anticholesteremic drug A substance used to lower plasma cholesterol levels. FYPO_relaxed.owl CHEBI:35856 biolink:NamedThing lipoxygenase inhibitor A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes. FYPO_relaxed.owl CHEBI:76837 biolink:NamedThing EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor An EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor that inhibits the action of any oxidoreductase incorporating 2 atoms of oxygen (EC 1.13.11.*). FYPO_relaxed.owl CHEBI:38514 biolink:NamedThing quinoline alkaloid fundamental parent FYPO_relaxed.owl CHEBI:35983 biolink:NamedThing 7-oxo monocarboxylic acid FYPO_relaxed.owl CHEBI:36094 biolink:NamedThing organic chloride salt FYPO_relaxed.owl CHEBI:51069 biolink:NamedThing organic halide salt FYPO_relaxed.owl CHEBI:48369 biolink:NamedThing organic bromide salt FYPO_relaxed.owl CHEBI:36219 biolink:NamedThing alpha-lactose The alpha-anomer of lactose. FYPO_relaxed.owl CHEBI:36344 biolink:NamedThing hadron Hadron is a subatomic particle which experiences the strong force. FYPO_relaxed.owl CHEBI:36401 biolink:NamedThing cycloalkadiene An unsaturated monocyclic hydrocarbon having two endocyclic double bonds. FYPO_relaxed.owl CHEBI:36403 biolink:NamedThing monocyclic olefin A monocyclic hydrocarbon having any number of double bonds. FYPO_relaxed.owl CHEBI:37932 biolink:NamedThing phenothiazine FYPO_relaxed.owl CHEBI:51245 biolink:NamedThing phenanthridines Any dibenzopyridine based on the skeleton of phenanthridine and its substituted derivatives thereof. FYPO_relaxed.owl CHEBI:42478 biolink:NamedThing ethidium The fluorescent compound widely used in experimental cell biology and biochemistry to reveal double-stranded DNA and RNA. FYPO_relaxed.owl CHEBI:3752 biolink:NamedThing clomiphene FYPO_relaxed.owl CHEBI:36608 biolink:NamedThing acyclic acid anhydride FYPO_relaxed.owl CHEBI:36623 biolink:NamedThing 4H-benzimidazole FYPO_relaxed.owl CHEBI:36639 biolink:NamedThing 2H-benzimidazole FYPO_relaxed.owl CHEBI:36641 biolink:NamedThing 3aH-benzimidazole FYPO_relaxed.owl CHEBI:36628 biolink:NamedThing 1,8-naphthyridine A naphthyridine in which the nitrogens are situated at positions 1 and 8. FYPO_relaxed.owl CHEBI:36807 biolink:NamedThing hydrochloride A salt formally resulting from the reaction of hydrochloric acid with an organic base. FYPO_relaxed.owl CHEBI:41688 biolink:NamedThing crystal violet An organic chloride salt that is the monochloride salt of crystal violet cation. It has been used in creams for the topical treatment of bacterial and fungal infections, being effective against some Gram-positive bacteria (notably Staphylococcus species) and some pathogenic fungi (including Candida species) but use declined following reports of animal carcinogenicity. It has also been used for dying wood, silk, and paper, as well as a histological stain. FYPO_relaxed.owl CHEBI:37075 biolink:NamedThing ribonucleoside 5'-diphosphate FYPO_relaxed.owl CHEBI:57865 biolink:NamedThing uridine 5'-monophosphate(2-) A pyrimidine nucleoside 5'-monophosphate(2-) that results from the removal of two protons from the phosphate group of UMP. FYPO_relaxed.owl CHEBI:37070 biolink:NamedThing 2-methylbutyric acid A methylbutyric acid comprising a butyric acid core carrying a 2-methyl substituent. Produced from amino acid leucine during nutrient starvation in bacteria. FYPO_relaxed.owl CHEBI:37193 biolink:NamedThing elemental lead FYPO_relaxed.owl CHEBI:37237 biolink:NamedThing elemental molybdenum FYPO_relaxed.owl CHEBI:37334 biolink:NamedThing diagnostic imaging agent A substance administered to enhance contrast in images of the inside of the body obtained using X-rays, gamma-rays, sound waves, radio waves (MRI), or radioactive particles in order to diagnose disease. FYPO_relaxed.owl CHEBI:37335 biolink:NamedThing MRI contrast agent FYPO_relaxed.owl CHEBI:37338 biolink:NamedThing radioopaque medium A substance having the property of absorbing, and therefore being opaque to, electromagnetic radiation, particularly X-rays. FYPO_relaxed.owl CHEBI:37568 biolink:NamedThing dTTP(4-) A 2'-deoxyribonucleoside 5'-triphosphate(4-) obtained by deprotonation of the four triphosphate OH groups of dTTP; major species at pH 7.3. FYPO_relaxed.owl CHEBI:61560 biolink:NamedThing 2'-deoxyribonucleoside 5'-triphosphate(4-) A 2'-deoxyribonucleoside triphosphate oxoanion being the tetraanion formed by global deprotonation of the triphosphate group. FYPO_relaxed.owl CHEBI:61404 biolink:NamedThing dATP(4-) A 2'-deoxyribonucleoside 5'-triphosphate(4-) that is the tetraanion of 2'-deoxyadenosine 5'-triphosphate (dATP), arising from deprotonation of the four triphosphate OH groups; major species at pH 7.3. FYPO_relaxed.owl CHEBI:61429 biolink:NamedThing dGTP(4-) A 2'-deoxyribonucleoside 5'-triphosphate(4-) that is the tetraanion of 2'-deoxyguanosine 5'-triphosphate (dGTP), arising from deprotonation of the four triphosphate OH groups; major species at pH 7.3. FYPO_relaxed.owl CHEBI:61481 biolink:NamedThing dCTP(4-) A 2'-deoxyribonucleoside 5'-triphosphate(4-) arising from deprotonation of the triphosphate OH groups of 2'-deoxycytidine 5'-triphosphate (dCTP); major species at pH 7.3. FYPO_relaxed.owl CHEBI:37604 biolink:NamedThing cis-octadec-9-ene FYPO_relaxed.owl CHEBI:37605 biolink:NamedThing octadec-9-ene FYPO_relaxed.owl CHEBI:37606 biolink:NamedThing octadecene An alkene that is octadecane containing one double bond at unspecified position. FYPO_relaxed.owl CHEBI:37627 biolink:NamedThing L-glucopyranose The L-enantiomer of glucopyranose. FYPO_relaxed.owl CHEBI:37631 biolink:NamedThing beta-L-glucose A L-glucopyranose with a beta-configuration at the anomeric position. FYPO_relaxed.owl CHEBI:87069 biolink:NamedThing imidazole antifungal drug Any imidazole antifungal agent that has been used for the treatment of fungal infections in humans or animals. FYPO_relaxed.owl CHEBI:87071 biolink:NamedThing conazole antifungal drug Any conazole antifungal agent that has been used for the treatment of fungal infections in animals or humans. FYPO_relaxed.owl CHEBI:37670 biolink:NamedThing protease inhibitor A compound which inhibits or antagonizes the biosynthesis or actions of proteases (endopeptidases). FYPO_relaxed.owl CHEBI:60258 biolink:NamedThing EC 3.4.* (hydrolases acting on peptide bond) inhibitor A hydrolase inhibitor that interferes with the action of any hydrolase acting on peptide bonds (peptidase), EC 3.4.*.*). FYPO_relaxed.owl CHEBI:5924 biolink:NamedThing EC 3.4.21.* (serine endopeptidase) inhibitor Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that inhibits the activity of a serine endopeptidase (EC 3.4.21.*). FYPO_relaxed.owl CHEBI:37699 biolink:NamedThing protein kinase inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases. FYPO_relaxed.owl CHEBI:76668 biolink:NamedThing EC 2.7.* (P-containing group transferase) inhibitor A transferase inhibitor that inhibits the action of a phosphorus-containing group transferase (EC 2.7.*.*). FYPO_relaxed.owl CHEBI:50916 biolink:NamedThing lipid kinase inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of lipid kinases. FYPO_relaxed.owl CHEBI:76815 biolink:NamedThing EC 2.7.7.* (nucleotidyltransferase) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any nucleotidyltransferase (EC 2.7.7.*). FYPO_relaxed.owl CHEBI:76816 biolink:NamedThing EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with any enzyme in the EC 2.7.8.* (transferases for other substituted phosphate groups) category. FYPO_relaxed.owl CHEBI:76881 biolink:NamedThing EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any phosphotransferase with an alcohol group as acceptor (EC 2.7.1.*). FYPO_relaxed.owl CHEBI:37700 biolink:NamedThing EC 2.7.11.13 (protein kinase C) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13). FYPO_relaxed.owl CHEBI:76812 biolink:NamedThing EC 2.7.11.* (protein-serine/threonine kinase) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-serine/threonine kinase (EC 2.7.11.*). FYPO_relaxed.owl CHEBI:50925 biolink:NamedThing EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of non-specific serine/threonine protein kinase (EC 2.7.11.1), a kinase enzyme involved in phosphorylation of hydroxy group of serine or threonine. FYPO_relaxed.owl CHEBI:78763 biolink:NamedThing EC 2.7.11.18 (myosin-light-chain kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of myosin-light-chain kinase (EC 2.7.11.18). FYPO_relaxed.owl CHEBI:79091 biolink:NamedThing EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of mitogen-activated protein kinase (EC 2.7.11.24). FYPO_relaxed.owl CHEBI:85094 biolink:NamedThing EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cAMP-dependent protein kinase (EC 2.7.11.11). FYPO_relaxed.owl CHEBI:85113 biolink:NamedThing EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitor An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of cGMP-dependent protein kinase (EC 2.7.11.12). FYPO_relaxed.owl CHEBI:37786 biolink:NamedThing acyclic phosphorus acid anhydride FYPO_relaxed.owl CHEBI:37887 biolink:NamedThing adrenergic antagonist An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists. FYPO_relaxed.owl CHEBI:37962 biolink:NamedThing adrenergic agent Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter. FYPO_relaxed.owl CHEBI:48539 biolink:NamedThing alpha-adrenergic drug Any drug that acts on an alpha-adrenergic receptor. FYPO_relaxed.owl CHEBI:37890 biolink:NamedThing alpha-adrenergic antagonist An agent that binds to but does not activate alpha-adrenergic receptors thereby blocking the actions of endogenous or exogenous alpha-adrenergic agonists. alpha-Adrenergic antagonists are used in the treatment of hypertension, vasospasm, peripheral vascular disease, shock, and pheochromocytoma. FYPO_relaxed.owl CHEBI:38835 biolink:NamedThing xanthenes FYPO_relaxed.owl CHEBI:37930 biolink:NamedThing phenothiazine antipsychotic drug FYPO_relaxed.owl CHEBI:65190 biolink:NamedThing first generation antipsychotic Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased. FYPO_relaxed.owl CHEBI:37931 biolink:NamedThing 10H-phenothiazine The 10H-tautomer of phenothiazine. FYPO_relaxed.owl CHEBI:37933 biolink:NamedThing 4aH-phenothiazine FYPO_relaxed.owl CHEBI:37934 biolink:NamedThing 1H-phenothiazine FYPO_relaxed.owl CHEBI:37935 biolink:NamedThing 3H-phenothiazine FYPO_relaxed.owl CHEBI:38323 biolink:NamedThing cholinergic drug Any drug used for its actions on cholinergic systems. Included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons. FYPO_relaxed.owl CHEBI:48560 biolink:NamedThing dopaminergic agent A drug used for its effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. FYPO_relaxed.owl CHEBI:50103 biolink:NamedThing excitatory amino acid agonist An agent that binds to and activates excitatory amino acid receptors. FYPO_relaxed.owl CHEBI:51374 biolink:NamedThing GABA agent A substance, such as agonists, antagonists, degradation or uptake inhibitors, depleters, precursors, and modulators of receptor function, used for its pharmacological actions on GABAergic systems. FYPO_relaxed.owl CHEBI:37963 biolink:NamedThing pyranone Any of a class of cyclic chemical compounds that contain an unsaturated six-membered ring with one ring oxygen atom and an oxo substituent. FYPO_relaxed.owl CHEBI:38068 biolink:NamedThing antimalarial A drug used in the treatment of malaria. Antimalarials are usually classified on the basis of their action against Plasmodia at different stages in their life cycle in the human. FYPO_relaxed.owl CHEBI:38109 biolink:NamedThing (R)-azetidine-2-carboxylic acid FYPO_relaxed.owl CHEBI:6198 biolink:NamedThing (S)-azetidine-2-carboxylic acid The (S)-enantiomer of azetidine-2-carboxylic acid. FYPO_relaxed.owl CHEBI:38128 biolink:NamedThing monothiocarbamic ester A thiocarbamic ester formally derived from a monothiocarbamic acid. FYPO_relaxed.owl CHEBI:38131 biolink:NamedThing lactol Cyclic hemiacetals formed by intramolecular addition of a hydroxy group to an aldehydic or ketonic carbonyl group. They are thus 1-oxacycloalkan-2-ols or unsaturated analogues. FYPO_relaxed.owl CHEBI:59772 biolink:NamedThing hemiketal A hemiacetal having the structure RR(1)C(OH)OR(2) (R, R(1), R(2) =/= H), derived from a ketone by formal addition of an alcohol to the carbonyl group. FYPO_relaxed.owl CHEBI:38809 biolink:NamedThing ryanodine receptor modulator FYPO_relaxed.owl CHEBI:38216 biolink:NamedThing 3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonate) FYPO_relaxed.owl CHEBI:38217 biolink:NamedThing 3,3'-(biphenyl-4,4'-diyldidiazene-2,1-diyl)bis(4-aminonaphthalene-1-sulfonic acid) FYPO_relaxed.owl CHEBI:38234 biolink:NamedThing DNA polymerase inhibitor Any inhibitor of a DNA polymerase. FYPO_relaxed.owl CHEBI:38267 biolink:NamedThing boronic acid The simplest boronic acid, consisting of borane with two of the hydrogens substituted by hydroxy groups. FYPO_relaxed.owl CHEBI:38269 biolink:NamedThing boronic acids Compounds having the structure RB(OH)2. FYPO_relaxed.owl CHEBI:38355 biolink:NamedThing hex-4-enoic acid A hexenoic acid with the double bond at position 4. FYPO_relaxed.owl CHEBI:38462 biolink:NamedThing EC 3.1.1.7 (acetylcholinesterase) inhibitor An EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that interferes with the action of enzyme acetylcholinesterase (EC 3.1.1.7), which helps breaking down of acetylcholine into choline and acetic acid. FYPO_relaxed.owl CHEBI:76773 biolink:NamedThing EC 3.1.1.* (carboxylic ester hydrolase) inhibitor An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a carboxylic ester hydrolase (EC 3.1.1.*). FYPO_relaxed.owl CHEBI:65001 biolink:NamedThing EC 3.1.1.3 (triacylglycerol lipase) inhibitor Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of triacylglycerol lipase (EC 3.1.1.3). FYPO_relaxed.owl CHEBI:78444 biolink:NamedThing EC 3.1.1.1 (carboxylesterase) inhibitor Any EC 3.1.1.* (carboxylic ester hydrolase) inhibitor that inhibits the action of carboxylesterase (EC 3.1.1.1 ). FYPO_relaxed.owl CHEBI:76870 biolink:NamedThing EC 1.9.3.* (oxidoreductase acting on donor heme group, oxygen as acceptor) inhibitor An EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.9.3.*). FYPO_relaxed.owl CHEBI:76866 biolink:NamedThing EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor An EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor that interferes with the action of any such enzyme using a quinone or similar as acceptor (EC 1.6.5.*). FYPO_relaxed.owl CHEBI:50390 biolink:NamedThing EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor An EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor that interferes with the action of NAD(P)H dehydrogenase (quinone), EC 1.6.5.2. FYPO_relaxed.owl CHEBI:38582 biolink:NamedThing difluorobenzene Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying two fluorine atoms. FYPO_relaxed.owl CHEBI:83575 biolink:NamedThing monofluorobenzenes Any member of the class of fluorobenzenes containing a mono- or poly-substituted benzene ring carrying a single fluorine substitutent. FYPO_relaxed.owl CHEBI:38584 biolink:NamedThing 1,3-difluorobenzene A difluorobenzene carrying fluoro groups at positions 1 and 3. FYPO_relaxed.owl CHEBI:86426 biolink:NamedThing triazole antifungal agent A member of the class of triazole that has significant antifungal properties. FYPO_relaxed.owl CHEBI:38633 biolink:NamedThing sodium channel blocker An agent that inhibits sodium influx through cell membranes. FYPO_relaxed.owl CHEBI:38637 biolink:NamedThing tyrosine kinase inhibitor Any protein kinase inhibitor that interferes with the action of tyrosine kinase. FYPO_relaxed.owl CHEBI:68481 biolink:NamedThing mTOR inhibitor A protein kinase inhibitor of the mammalian target of rapamycin (mTOR), a protein that regulates cell growth, cell proliferation, cell motility, cell survival, protein synthesis and transcription. mTOR inhibitors are used to prevent transplant rejection and in treatment of cancer. FYPO_relaxed.owl CHEBI:70770 biolink:NamedThing Aurora kinase inhibitor Any protein kinase inhibitor that inhibits the action of an Aurora kinase (a group of serine/threonine kinases that are essential for cell proliferation). FYPO_relaxed.owl CHEBI:76817 biolink:NamedThing EC 2.7.10.* (protein-tyrosine kinase) inhibitor An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of any protein-tyrosine kinase (EC 2.7.10.*). FYPO_relaxed.owl CHEBI:39867 biolink:NamedThing valproic acid A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem. FYPO_relaxed.owl CHEBI:62499 biolink:NamedThing methyl-branched fatty acid Any branched-chain fatty acid containing methyl branches only. FYPO_relaxed.owl CHEBI:38655 biolink:NamedThing (S)-2-methylbutyric acid The (S)-enantiomer of 2-methylbutanoic acid. FYPO_relaxed.owl CHEBI:45525 biolink:NamedThing (R)-2-methylbutyric acid The (R)-enantiomer of 2-methylbutanoic acid. FYPO_relaxed.owl CHEBI:83635 biolink:NamedThing guanidinium salt An organic salt in which the cation has the structure (RN)2C=N(+)R2. FYPO_relaxed.owl CHEBI:38785 biolink:NamedThing morpholines Any compound containing morpholine as part of its structure. FYPO_relaxed.owl CHEBI:38934 biolink:NamedThing purvalanol FYPO_relaxed.owl CHEBI:39128 biolink:NamedThing magnesium ion FYPO_relaxed.owl CHEBI:39146 biolink:NamedThing trichostatin FYPO_relaxed.owl CHEBI:39158 biolink:NamedThing (R)-trichostatic acid FYPO_relaxed.owl CHEBI:39159 biolink:NamedThing (S)-trichostatic acid FYPO_relaxed.owl CHEBI:39179 biolink:NamedThing nitroguanidine An N-nitro compound that is guanidine in which one of the hydrogens is replaced by a nitro group. It can exist in distinct tautomeric forms, as 1-nitroguanidine (a nitroimine) or 2-nitroguanidine (a nitroamine); in both solid and in solution, the nitroimine form predominates. FYPO_relaxed.owl CHEBI:39442 biolink:NamedThing fluorescent probe A role played by a fluorescent molecular entity used to study the microscopic environment by fluorescence spectroscopy. FYPO_relaxed.owl CHEBI:67265 biolink:NamedThing beta-diketone A diketone in which the two keto groups are separated by a single carbon atom. FYPO_relaxed.owl CHEBI:87657 biolink:NamedThing octanoate ester Any fatty acid ester in which the carboxylic acid component is octanoic acid (caprylic acid). FYPO_relaxed.owl CHEBI:616459 biolink:NamedThing carbamimidoylazanium FYPO_relaxed.owl CHEBI:4139 biolink:NamedThing D-galactopyranose A galactopyranose having D-configuration. FYPO_relaxed.owl CHEBI:41981 biolink:NamedThing dideuterium oxide FYPO_relaxed.owl CHEBI:76107 biolink:NamedThing deuterated compound Any isotopically modified compound that has one or more hydrogen atoms replaced by deuterium. FYPO_relaxed.owl CHEBI:41983 biolink:NamedThing 4'-epidoxorubicinium An anthracycline cation resulting from the protonation of the amino group of 4'-epidoxorubicin. FYPO_relaxed.owl CHEBI:64816 biolink:NamedThing doxorubicin(1+) An anthracycline cation that is the conjugate acid of doxorubicin, arising from protonation of the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:42191 biolink:NamedThing EDTA(4-) A tetracarboxylic acid anion formed by deprotonation of all four carboxy groups in ethylenediaminetetraacetic acid (EDTA). FYPO_relaxed.owl CHEBI:63131 biolink:NamedThing EDTA(3-) A tetracarboxylic acid anion formed by deprotonation of three of the four carboxy groups in ethylenediaminetetraacetic acid (EDTA). FYPO_relaxed.owl CHEBI:64755 biolink:NamedThing EDTA(2-) A tetracarboxylic acid anion formed by deprotonation of two of the four carboxy groups in ethylenediaminetetraacetic acid (EDTA). FYPO_relaxed.owl CHEBI:44658 biolink:NamedThing okadaic acid A polycyclic ether that is produced by several species of dinoflagellates, and is known to accumulate in both marine sponges and shellfish. A polyketide, polyether derivative of a C38 fatty acid, it is one of the primary causes of diarrhetic shellfish poisoning (DSP). It is a potent inhibitor of specific protein phosphatases and is known to have a variety of negative effects on cells. FYPO_relaxed.owl CHEBI:7569 biolink:NamedThing nigericin A polyether antibiotic which affects ion transport and ATPase activity in mitochondria. It is produced by Streptomyces hygroscopicus. FYPO_relaxed.owl CHEBI:44667 biolink:NamedThing L-ornithinium(2+) The L-enantiomer of ornithinium(2+). FYPO_relaxed.owl CHEBI:45506 biolink:NamedThing alpha-D-ribose FYPO_relaxed.owl CHEBI:47013 biolink:NamedThing D-ribofuranose A ribofuranose having D-configuration. FYPO_relaxed.owl CHEBI:47002 biolink:NamedThing beta-D-ribose A D-ribofuranose in which the anomeric centre has beta-configuration. FYPO_relaxed.owl CHEBI:45599 biolink:NamedThing dodecyl hydrogen sulfate FYPO_relaxed.owl CHEBI:456216 biolink:NamedThing ADP(3-) A nucleoside 5'-diphosphate(3-) arising from deprotonation of all three diphosphate OH groups of adenosine 5'-diphosphate (ADP); major species present at pH 7.3. FYPO_relaxed.owl CHEBI:58069 biolink:NamedThing CDP(3-) A nucleoside 5'-diphosphate(3-) arising from deprotonation of the three triphosphate OH groups of cytidine 5'-diphosphate (CDP); major species at pH 7.3. FYPO_relaxed.owl CHEBI:58223 biolink:NamedThing UDP(3-) A nucleoside 5'-diphosphate(3-) arising from deprotonation of the diphosphate OH groups of uridine 5'-diphosphate (UDP); major species at pH 7.3. FYPO_relaxed.owl CHEBI:45716 biolink:NamedThing vorinostat A dicarboxylic acid diamide comprising suberic (octanedioic) acid coupled to aniline and hydroxylamine. A histone deacetylase inhibitor, it is marketed under the name Zolinza for the treatment of cutaneous T cell lymphoma (CTCL). FYPO_relaxed.owl CHEBI:46024 biolink:NamedThing trichostatin A FYPO_relaxed.owl CHEBI:46920 biolink:NamedThing N-methylpiperazine FYPO_relaxed.owl CHEBI:87101 biolink:NamedThing triazole antifungal drug Any triazole antifungal agent that has been used for the treatment of fungal infections in humans or animals. FYPO_relaxed.owl CHEBI:46245 biolink:NamedThing coenzyme Q10 A ubiquinone having a side chain of 10 isoprenoid units. In the naturally occurring isomer, all isoprenyl double bonds are in the E- configuration. FYPO_relaxed.owl CHEBI:46812 biolink:NamedThing 1,3-oxazoles FYPO_relaxed.owl CHEBI:7916 biolink:NamedThing pantothenic acid A member of the class of pantothenic acids that is an amide formed from pantoic acid and beta-alanine. FYPO_relaxed.owl CHEBI:84410 biolink:NamedThing sphingoid base(1+) A cationic sphingoid obtained by protonation of the amino group of any 2-amino-1,3-dihydroxysphingoid base. FYPO_relaxed.owl CHEBI:47000 biolink:NamedThing L-ribofuranose An ribofuranose having L-configuration. FYPO_relaxed.owl CHEBI:47004 biolink:NamedThing alpha-L-ribose FYPO_relaxed.owl CHEBI:47005 biolink:NamedThing beta-L-ribose FYPO_relaxed.owl CHEBI:87633 biolink:NamedThing statin (semi-synthetic) A statin that is derived from a naturally occurring statin by partial chemical synthesis. FYPO_relaxed.owl CHEBI:47518 biolink:NamedThing (2S,4R)-ketoconazole A cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2S,4R)-configuration. FYPO_relaxed.owl CHEBI:86411 biolink:NamedThing cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine Either of the two diastereoisomers of 1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine in which the imidazol-1-ylmethyl group and the aryloxymethyl group are in a cis relationship to each other - i.e. they are both on the same side of the plane of the dioxolane ring. The antifungal drug ketoconazole is a racemic mixture of the two cis diastereoisomers. FYPO_relaxed.owl CHEBI:48336 biolink:NamedThing (2R,4S)-ketoconazole A cis-1-acetyl-4-(4-{[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazine which dioxolane moiety has (2R,4S)-configuration. FYPO_relaxed.owl CHEBI:47600 biolink:NamedThing purvalanol A FYPO_relaxed.owl CHEBI:48353 biolink:NamedThing serine proteinase inhibitor An exogenous or endogenous compound which inhibits serine endopeptidases. FYPO_relaxed.owl CHEBI:59107 biolink:NamedThing EC 3.4.24.* (metalloendopeptidase) inhibitor Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*). FYPO_relaxed.owl CHEBI:64926 biolink:NamedThing serine protease inhibitor Any protease inhibitor that restricts the action of a serine protease. FYPO_relaxed.owl CHEBI:76779 biolink:NamedThing EC 3.4.21.26 (prolyl oligopeptidase) inhibitor Any EC 3.4.21.* (serine endopeptidase) inhibitor that interferes with the action of prolyl oligopeptidase (EC 3.4.21.26). FYPO_relaxed.owl CHEBI:48354 biolink:NamedThing polar solvent A solvent that is composed of polar molecules. Polar solvents can dissolve ionic compounds or ionisable covalent compounds. FYPO_relaxed.owl CHEBI:48355 biolink:NamedThing non-polar solvent FYPO_relaxed.owl CHEBI:48357 biolink:NamedThing aprotic solvent FYPO_relaxed.owl CHEBI:48358 biolink:NamedThing polar aprotic solvent A solvent with a comparatively high relative permittivity (or dielectric constant), greater than ca. 15, and a sizable permanent dipole moment, that cannot donate suitably labile hydrogen atoms to form strong hydrogen bonds. FYPO_relaxed.owl CHEBI:48359 biolink:NamedThing protophilic solvent Solvent that is capable of acting as a hydron (proton) acceptor. FYPO_relaxed.owl CHEBI:48360 biolink:NamedThing amphiprotic solvent Self-ionizing solvent possessing both characteristics of Bronsted acids and bases. FYPO_relaxed.owl CHEBI:48379 biolink:NamedThing isourea A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives. FYPO_relaxed.owl CHEBI:51039 biolink:NamedThing dopamine uptake inhibitor A dopaminergic agent that blocks the transport of dopamine into axon terminals or into storage vesicles within terminals. Most of the adrenergic uptake inhibitors also inhibit dopamine uptake. FYPO_relaxed.owl CHEBI:48578 biolink:NamedThing radical scavenger A role played by a substance that can react readily with, and thereby eliminate, radicals. FYPO_relaxed.owl CHEBI:48819 biolink:NamedThing cyano group FYPO_relaxed.owl CHEBI:4883 biolink:NamedThing ethidium bromide The organic bromide salt of ethidium. FYPO_relaxed.owl CHEBI:53233 biolink:NamedThing 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide The bromide salt of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium. FYPO_relaxed.owl CHEBI:48861 biolink:NamedThing 2-trans,6-trans,10-trans-geranylgeranyl diphosphate The all-trans-isomer of geranylgeranyl diphosphate. FYPO_relaxed.owl CHEBI:48873 biolink:NamedThing cholinergic antagonist Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists. FYPO_relaxed.owl CHEBI:48876 biolink:NamedThing muscarinic antagonist A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists. FYPO_relaxed.owl CHEBI:48891 biolink:NamedThing thiazolidinone FYPO_relaxed.owl CHEBI:48923 biolink:NamedThing erythromycin Any of several wide-spectrum macrolide antibiotics obtained from actinomycete Saccharopolyspora erythraea (formerly known as Streptomyces erythraeus). FYPO_relaxed.owl CHEBI:48958 biolink:NamedThing 1,1'-azobis(N,N-dimethylformamide) FYPO_relaxed.owl CHEBI:48959 biolink:NamedThing monoazo compound Compounds containing single -N=N- group. FYPO_relaxed.owl CHEBI:49032 biolink:NamedThing L-methionine (R)-S-oxide The (R)-oxido diastereomer of L-methionine S-oxide. FYPO_relaxed.owl CHEBI:49036 biolink:NamedThing D-methionine (S)-S-oxide FYPO_relaxed.owl CHEBI:88066 biolink:NamedThing dioctanoylglycerol A diglyceride obtained by acylation of any two hydroxy groups of glycerol by octanoic acid. Formula C19H36O5. For the structure shown, either R1 = H and R2 = octanoyl or R1 = octanoyl and R2 = H. FYPO_relaxed.owl CHEBI:49200 biolink:NamedThing EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H(+)/K(+)-exchanging ATPase, EC 3.6.3.10. Such compounds are also known as proton pump inhibitors. FYPO_relaxed.owl CHEBI:73214 biolink:NamedThing EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of H(+)-transporting two-sector ATPase inhibitor (EC 3.6.3.14). FYPO_relaxed.owl CHEBI:77748 biolink:NamedThing EC 3.6.3.44 (xenobiotic-transporting ATPase) inhibitor An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that interferes with the action of xenobiotic-transporting ATPase (EC 3.6.3.44). FYPO_relaxed.owl CHEBI:49323 biolink:NamedThing contraceptive drug A chemical substance that prevents or reduces the probability of conception. FYPO_relaxed.owl CHEBI:50691 biolink:NamedThing abortifacient A chemical substance that interrupts pregnancy after implantation. FYPO_relaxed.owl CHEBI:495505 biolink:NamedThing dATP(3-) A 2'-deoxyribonucleoside triphosphate oxoanion that is the trianion of 2'-deoxyadenosine 5'-triphosphate, arising from deprotonation of three of the four triphosphate OH groups. FYPO_relaxed.owl CHEBI:57724 biolink:NamedThing dCTP(3-) A 2'-deoxyribonucleoside triphosphate oxoanion that is a trianion of 2'-deoxycytidine 5'-triphosphate, arising from deprotonation of three of the four triphosphate OH groups. FYPO_relaxed.owl CHEBI:57794 biolink:NamedThing dGTP(3-) A 2'-deoxyribonucleoside triphosphate oxoanion that is a trianion of dGTP, arising from deprotonation of three of the four triphosphate OH groups. FYPO_relaxed.owl CHEBI:58370 biolink:NamedThing dTTP(3-) A 2'-deoxyribonucleoside triphosphate oxoanion obtained from thymidine 5'-triphosphate by deprotonation of three of the four triphosphate OH groups. FYPO_relaxed.owl CHEBI:50112 biolink:NamedThing sex hormone Any hormone that is responsible for controlling sexual characteristics and reproductive function. FYPO_relaxed.owl CHEBI:50114 biolink:NamedThing estrogen A hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals by binding to oestrogen receptors. The oestrogens are named for their importance in the oestrous cycle. The oestrogens that occur naturally in the body, notably estrone, estradiol, estriol, and estetrol are steroids. Other compounds with oestrogenic activity are produced by plants (phytoestrogens) and fungi (mycoestrogens); synthetic compounds with oestrogenic activity are known as xenoestrogens. FYPO_relaxed.owl CHEBI:87134 biolink:NamedThing morpholine fungicide Any morpholine antifungal agent used as a fungicide. FYPO_relaxed.owl CHEBI:50146 biolink:NamedThing (S)-fenpropimorph A 4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine in which the methyl substituents on the morpholine ring are in a cis relationship to each other and in which the remaining stereocentre has S configuration. FYPO_relaxed.owl CHEBI:50148 biolink:NamedThing 4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine A member of the class of morpholines that is 2,6-dimethylmorpholine in which the hydrogen attached to the nitrogen is replaced by a 3-(p-tert-butylphenyl)-2-methylpropyl group. FYPO_relaxed.owl CHEBI:50147 biolink:NamedThing (R)-fenpropimorph A 4-[3-(4-tert-butylphenyl)-2-methylpropyl]-2,6-dimethylmorpholine in which the methyl substituents on the morpholine ring are in a cis relationship to each other and in which the remaining stereocentre has R configuration. FYPO_relaxed.owl CHEBI:87132 biolink:NamedThing morpholine antifungal agent A member of the class of morpholines that has significant antifungal properties. FYPO_relaxed.owl CHEBI:50176 biolink:NamedThing keratolytic drug A drug that softens, separates, and causes desquamation of the cornified epithelium or horny layer of skin. Keratolytic drugs are used to expose mycelia of infecting fungi or to treat corns, warts, and certain other skin diseases. FYPO_relaxed.owl CHEBI:50183 biolink:NamedThing P450 inhibitor An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. FYPO_relaxed.owl CHEBI:76898 biolink:NamedThing EC 1.14.14.1 (unspecific monooxygenase) inhibitor An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor that interferes with the action of an unspecified monooxygenase (EC 1.14.14.1). FYPO_relaxed.owl CHEBI:50218 biolink:NamedThing EC 3.1.4.* (phosphoric diester hydrolase) inhibitor An EC 3.1.* (ester hydrolase) inhibitor that interferes with the action of a phosphoric diester hydrolase (EC 3.1.4.*). FYPO_relaxed.owl CHEBI:76760 biolink:NamedThing EC 3.1.* (ester hydrolase) inhibitor A hydrolase inhibitor that interferes with the action of any ester hydrolase (EC 3.1.*.*). FYPO_relaxed.owl CHEBI:50249 biolink:NamedThing anticoagulant An agent that prevents blood clotting. FYPO_relaxed.owl CHEBI:50427 biolink:NamedThing platelet aggregation inhibitor A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. FYPO_relaxed.owl CHEBI:50276 biolink:NamedThing EC 5.99.1.2 (DNA topoisomerase) inhibitor A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. FYPO_relaxed.owl CHEBI:70727 biolink:NamedThing topoisomerase inhibitor An EC 5.99.1.* (miscellaneous isomerase) inhibitor that interferes with the action of any of the topoisomerases (enzymes that regulate the overwinding or underwinding of DNA). FYPO_relaxed.owl CHEBI:50750 biolink:NamedThing EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (also known as topoisomerase II and as DNA gyrase), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. FYPO_relaxed.owl CHEBI:50297 biolink:NamedThing canonical nucleotide residue FYPO_relaxed.owl CHEBI:50298 biolink:NamedThing canonical deoxyribonucleotide residue FYPO_relaxed.owl CHEBI:50299 biolink:NamedThing canonical ribonucleotide residue FYPO_relaxed.owl CHEBI:50505 biolink:NamedThing sweetening agent Substance that sweeten food, beverages, medications, etc. FYPO_relaxed.owl CHEBI:50509 biolink:NamedThing potassium channel blocker An agent that inhibits cell membrane glycoproteins that are selectively permeable to potassium ions. FYPO_relaxed.owl CHEBI:50526 biolink:NamedThing phenolate A phenolate anion that is the conjugate base of phenol obtained by deprotonation of the OH group. FYPO_relaxed.owl CHEBI:50683 biolink:NamedThing EC 1.5.1.3 (dihydrofolate reductase) inhibitor An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3). FYPO_relaxed.owl CHEBI:73913 biolink:NamedThing antifolate An antimetabolite that impairs the action of folic acids FYPO_relaxed.owl CHEBI:76863 biolink:NamedThing EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD(+) or NADP(+) as acceptor) inhibitor An EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.5.1.*). FYPO_relaxed.owl CHEBI:50772 biolink:NamedThing 2-decaprenyl-6-methoxy-3-methyl-1,4-benzoquinone A polyprenylbenzoquinone that is 2-decaprenyl-1,4-benzoquinone carrying additional methyl and methoxy substituents at positions 3 and 6 respectively. FYPO_relaxed.owl CHEBI:50837 biolink:NamedThing estrogen antagonist A compound which inhibits or antagonises the biosynthesis or actions of estrogens. FYPO_relaxed.owl CHEBI:50903 biolink:NamedThing carcinogenic agent A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. FYPO_relaxed.owl CHEBI:50904 biolink:NamedThing allergen A chemical compound, or part thereof, which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. FYPO_relaxed.owl CHEBI:50905 biolink:NamedThing teratogenic agent A role played by a chemical compound in biological systems with adverse consequences in embryo developments, leading to birth defects, embryo death or altered development, growth retardation and functional defect. FYPO_relaxed.owl CHEBI:50908 biolink:NamedThing hepatotoxic agent A role played by a chemical compound exihibiting itself through the ability to induce damage to the liver in animals. FYPO_relaxed.owl CHEBI:50909 biolink:NamedThing nephrotoxic agent A role played by a chemical compound exihibiting itself through the ability to induce damage to the kidney in animals. FYPO_relaxed.owl PATO:0000001 biolink:NamedThing quality A dependent entity that inheres in a bearer by virtue of how the bearer is related to other entities FYPO_relaxed.owl PATO:0000068 biolink:NamedThing qualitative FYPO_relaxed.owl PATO:0001236 biolink:NamedThing process quality A quality which inheres in an process. FYPO_relaxed.owl PATO:0001241 biolink:NamedThing physical object quality A quality which inheres in a continuant. FYPO_relaxed.owl PATO:0002300 biolink:NamedThing increased quality A quality that has a value that is increased compared to normal or average. FYPO_relaxed.owl PATO:0002301 biolink:NamedThing decreased quality A quality that has a value that is decreased compared to normal or average. FYPO_relaxed.owl CHEBI:50914 biolink:NamedThing EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor An inhibitor of phosphatidylinositol 3-kinase, EC 2.7.1.137, a family of related enzymes capable of phosphorylating the 3 position hydroxy group of the inositol ring of a phosphatidylinositol. FYPO_relaxed.owl CHEBI:78366 biolink:NamedThing EC 2.7.1.1 (hexokinase) inhibitor An EC 2.7.1.* (phosphotransferases with an alcohol group as acceptor) inhibitor that interferes with the action of hexokinase, EC 2.7.1.1, an enzyme that phosphorylates hexoses forming hexose phosphate. FYPO_relaxed.owl CHEBI:61774 biolink:NamedThing inositol phosphorylceramide synthase inhibitor An enzyme inhibitor that inhibits the action of inositol phosphorylceramide synthase. FYPO_relaxed.owl CHEBI:51085 biolink:NamedThing organic nitrate salt FYPO_relaxed.owl CHEBI:51121 biolink:NamedThing fluorescent dye FYPO_relaxed.owl CHEBI:77178 biolink:NamedThing histological dye A dye used in microscopic or electron microscopic examination of cells and tissues to give contrast and to highlight particular features of interest, such as nuclei and cytoplasm. FYPO_relaxed.owl CHEBI:51153 biolink:NamedThing phosphorus ylide A compound where a formally positive phosphorus atom is bound to a formally negative carbon atom. FYPO_relaxed.owl CHEBI:51217 biolink:NamedThing fluorochrome A fluorescent dye used to stain biological specimens. FYPO_relaxed.owl CHEBI:51234 biolink:NamedThing magnesium halide FYPO_relaxed.owl CHEBI:51373 biolink:NamedThing GABA agonist A drug that binds to and activates gamma-aminobutyric acid receptors. FYPO_relaxed.owl CHEBI:51659 biolink:NamedThing dihydrofuran Compounds containing a mono-unsaturated furan ring skeleton. FYPO_relaxed.owl CHEBI:51839 biolink:NamedThing alpha-haloketone A haloketone in which the halogen and oxo substituents are on adjacent carbon atoms. FYPO_relaxed.owl CHEBI:51842 biolink:NamedThing bromoketone A ketone containing a bromo substituent. FYPO_relaxed.owl CHEBI:51841 biolink:NamedThing alpha-chloroketone A chloroketone in which the chlorine and oxo substituents are on adjacent carbon atoms. FYPO_relaxed.owl CHEBI:51843 biolink:NamedThing alpha-bromoketone A bromoketone in which the bromine and oxo substituents are on adjacent carbon atoms. FYPO_relaxed.owl CHEBI:52310 biolink:NamedThing 1-NA-PP1 FYPO_relaxed.owl CHEBI:52641 biolink:NamedThing polyphosphoric acid A polymerized phosphorus oxoacid of general formula HO[PO2OH]nH formed by condensation of orthophosphoric acid molecules and containing a backbone chain consisting of alternating P and O atoms covalently bonded together. FYPO_relaxed.owl CHEBI:52646 biolink:NamedThing leptomycin B A leptomycin having a (2E,10E,12E,16Z,18E)-double bond configuration as well as an ethyl substituent at position 17. FYPO_relaxed.owl CHEBI:53019 biolink:NamedThing glycan G00008 A dolichyl diphosphooligosaccharide compound consisting of a branched tetradecasaccharide attached to the dolichyl chain via a diphosphate linkage. FYPO_relaxed.owl CHEBI:53121 biolink:NamedThing adenosine A2A receptor antagonist An antagonist at the A2A receptor. FYPO_relaxed.owl CHEBI:70725 biolink:NamedThing adenosine A3 receptor antagonist An antagonist at the A3 receptor. FYPO_relaxed.owl CHEBI:5717 biolink:NamedThing high-mannose oligosaccharide Any oligosaccharide derivative which typically contains unsubstituted terminal mannose sugars with between five and nine mannose residues attached to the chitobiose [(GlcNAc)2] core. FYPO_relaxed.owl CHEBI:57288 biolink:NamedThing acetyl-CoA(4-) An acyl-CoA(4-) that is the tetraanion of acetyl-CoA, arising from deprotonation of the phosphate and diphosphate OH groups. FYPO_relaxed.owl CHEBI:77636 biolink:NamedThing fatty acyl-CoA(4-) An acyl-CoA(4-) arising from deprotonation of the phosphate and diphosphate OH groups of any fatty acyl-CoA; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57378 biolink:NamedThing glutaryl-CoA(5-) An acyl-CoA oxoanion that is the pentaanion of glutaryl-CoA arising from deprotonation of phosphate, diphosphate and carboxylic acid functions. FYPO_relaxed.owl CHEBI:57416 biolink:NamedThing D-alanine zwitterion Zwitterionic form of D-alanine. FYPO_relaxed.owl CHEBI:57972 biolink:NamedThing L-alanine zwitterion Zwitterionic form of L-alanine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57603 biolink:NamedThing ethanolaminium(1+) A primary aliphatic ammonium ion that is the conjugate acid of ethanolamine arising from protonation of the primary amino function. FYPO_relaxed.owl CHEBI:57613 biolink:NamedThing phosphatidylethanolamine zwitterion The zwitterion of a phosphatidylethanolamine compound formed by proton transfer from the phosphate to the primary amino group. FYPO_relaxed.owl CHEBI:78201 biolink:NamedThing monoacylglycero-3-phosphoethanolamine zwitterion A glycerophosphoethanolamine zwitterion obtained by transfer of a proton from the phosphate to the amino group of any monoacylglycero-3-phosphoethanolamine; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57658 biolink:NamedThing 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate(5-) An organophosphate oxoanion obtained via global deprotonation of the phosphate OH groups of 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate. FYPO_relaxed.owl CHEBI:57836 biolink:NamedThing 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-) The heptaanion of a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58456 biolink:NamedThing 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate(5-) The pentaanion of a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate. FYPO_relaxed.owl CHEBI:57705 biolink:NamedThing UDP-N-acetyl-alpha-D-glucosamine(2-) Dianion of UDP-N-acetyl-alpha-D-glucosamine arising from deprotonation of both free diphosphate OH groups; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57719 biolink:NamedThing D-tryptophan zwitterion Zwitterionic form of D-tryptophan having an anionic carboxy group and a protonated alpha-amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57817 biolink:NamedThing sphinganine(1+) A cationic sphingoid obtained by protonation of the amino group of sphinganine. FYPO_relaxed.owl CHEBI:64124 biolink:NamedThing phytosphingosine(1+) A cationic sphingoid that is the conjugate acid of phytosphingosine, obtained by protonation of the primary amino function; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57844 biolink:NamedThing L-methionine zwitterion Zwitterionic form of L-methionine having a anionic carboxy group and a cationic amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57932 biolink:NamedThing D-methionine zwitterion Zwitterionic form of D-methionine arising from transfer of a proton from the carboxy to the amino group; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57880 biolink:NamedThing 1-phosphatidyl-1D-myo-inositol(1-) The conjugate base of a 1-phosphatidyl-1D-myo-inositol; major species at pH 7.3. FYPO_relaxed.owl CHEBI:57939 biolink:NamedThing sphinganine 1-phosphate(1-) The anion resulting from the addition of a proton to the amino group and the removal of the two acidic protons from the phosphate group of sphinganine 1-phosphate. FYPO_relaxed.owl CHEBI:58104 biolink:NamedThing nucleoside 5'-triphoshate(3-) Trianion of nucleoside triphosphate arising from deprotonation of three of the four free triphosphate OH groups. FYPO_relaxed.owl CHEBI:61557 biolink:NamedThing nucleoside 5'-triphoshate(4-) A ribonucleoside triphosphate oxoanion arising from global deprotonation of the triphosphate groups of any nucleoside triphosphate; major species at pH 7.3. FYPO_relaxed.owl CHEBI:58436 biolink:NamedThing phosphatidyl-L-serine(1-) The conjugate base of a phosphatidyl-L-serine compound. FYPO_relaxed.owl CHEBI:58451 biolink:NamedThing pyridoxamine 5'-phosphate(1-) An organophosphate oxoanion that is the conjugate base of pyridoxamine 5'-phosphate. FYPO_relaxed.owl CHEBI:58496 biolink:NamedThing N-acetyl-D-amino acid anion The conjugate base of an N-acetyl-D-amino acid. FYPO_relaxed.owl CHEBI:58756 biolink:NamedThing 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) Trianion of 2-trans,6-trans,10-trans-geranylgeranyl diphosphate. FYPO_relaxed.owl CHEBI:58942 biolink:NamedThing amino-acid cation residue An amino-acid residue protonated on nitrogen. FYPO_relaxed.owl CHEBI:64769 biolink:NamedThing organic cationic group A cationic group that contains carbon. FYPO_relaxed.owl CHEBI:58943 biolink:NamedThing alpha-amino-acid cation residue An amino-acid cation residue in which the site of protonation is on the alpha-amino nitrogen. FYPO_relaxed.owl CHEBI:67013 biolink:NamedThing methyl-branched fatty acid anion Any branched-chain fatty acid anion containing methyl branches only. FYPO_relaxed.owl CHEBI:59063 biolink:NamedThing polymyxin B2 A polymyxin having a 6-methylheptanoyl group at the amino terminus. FYPO_relaxed.owl CHEBI:59080 biolink:NamedThing N-{alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->6)]-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue An N-glycan residue involved in post-translational modification of proteins. FYPO_relaxed.owl CHEBI:59082 biolink:NamedThing N-{alpha-Glc-(1->3)-alpha-Glc-(1->3)-alpha-Man-(1->2)-alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->3)-[alpha-Man-(1->2)-alpha-Man-(1->6)]-alpha-Man-(1->6)]-beta-Man-(1->4)-beta-GlcNAc-(1->4)-beta-GlcNAc}-L-Asn residue An N-glycan residue involved in post-translational modification of proteins. FYPO_relaxed.owl CHEBI:59163 biolink:NamedThing biomarker A substance used as an indicator of a biological state. FYPO_relaxed.owl CHEBI:59285 biolink:NamedThing EC 1.14.13.132 (squalene monooxygenase) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of squalene monooxygenase (EC 1.14.13.132). FYPO_relaxed.owl CHEBI:76841 biolink:NamedThing EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using NADH or NADPH as one donor (EC 1.14.13.*). FYPO_relaxed.owl CHEBI:61908 biolink:NamedThing EC 1.14.13.39 (nitric oxide synthase) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of nitric oxide synthase (EC 1.14.13.39). FYPO_relaxed.owl CHEBI:77781 biolink:NamedThing EC 1.14.13.181 (13-deoxydaunorubicin hydroxylase) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of 13-deoxydaunorubicin hydroxylase (EC 1.14.13.181). FYPO_relaxed.owl CHEBI:77884 biolink:NamedThing EC 1.14.13.70 (sterol 14alpha-demethylase) inhibitor An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of EC 1.14.13.70 (sterol 14alpha-demethylase). FYPO_relaxed.owl CHEBI:59579 biolink:NamedThing Man(a1-2)Man(a1-2)Man(a1-3)[Man(a1-2)Man(a1-3)[Man(a1-2)Man(a1-6)]Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc A branched N-glycan derivative that is an undecasaccharide derivative consisting of nine D-mannosyl residues and two N-acetylglucosamine residues (one at the reducing end). FYPO_relaxed.owl CHEBI:71275 biolink:NamedThing N-glycan derivative The term used to refer to the 'carbohydrate' portion of N-glycoproteins when attached to a nitrogen from asparagine or arginine side-chains, when this portion is a carbohydrate derivative. FYPO_relaxed.owl CHEBI:59647 biolink:NamedThing EC 2.3.1.50 (serine C-palmitoyltransferase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of serine palmitoyltransferase (EC 2.3.1.50). FYPO_relaxed.owl CHEBI:76878 biolink:NamedThing EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor An EC 2.3.* (acyltransferase) inhibitor that inhibits the action of any acyltransferase transferring groups other than amino-acyl groups (EC 2.3.1.*). FYPO_relaxed.owl CHEBI:63158 biolink:NamedThing EC 2.3.1.21 (carnitine O-palmitoyltransferase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of mitochondrial carnitine O-palmitoyltransferase (EC 2.3.1.21). FYPO_relaxed.owl CHEBI:71476 biolink:NamedThing EC 2.3.1.85 (fatty acid synthase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of fatty acid synthase (EC 2.3.1.85), a multi-enzyme protein involved in fatty acid synthesis. FYPO_relaxed.owl CHEBI:76395 biolink:NamedThing EC 2.3.1.48 (histone acetyltransferase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the function of histone acetyltransferase (EC 2.3.1.48). FYPO_relaxed.owl CHEBI:78691 biolink:NamedThing EC 2.3.1.97 (glycylpeptide N-tetradecanoyltransferase) inhibitor An EC 2.3.1.* (acyltransferase transferring other than amino-acyl group) inhibitor that interferes with the action of glycylpeptide N-tetradecanoyltransferase (EC 2.3.1.97). FYPO_relaxed.owl CHEBI:59777 biolink:NamedThing ketal An acetal of formula R2C(OR)2 (R =/= H) derived from a ketone by replacement of the oxo group by two hydrocarbyloxy groups. The class name 'ketals', once abandoned by IUPAC, has been reinstated as a subclass of acetals. FYPO_relaxed.owl CHEBI:77181 biolink:NamedThing crystal violet cation An iminium ion that is malachite green cation in which the hydrogen at the para- psition of the monosubstituted phenyl group is replaced by a dimethylamino group. FYPO_relaxed.owl CHEBI:76759 biolink:NamedThing EC 3.* (hydrolase) inhibitor Any enzyme inhibitor that interferes with the action of a hydrolase (EC 3.*.*.*). FYPO_relaxed.owl CHEBI:76764 biolink:NamedThing EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor Any hydrolase inhibitor that interferes with the action of a hydrolase acting on C-N bonds, other than peptide bonds (EC 3.5.*.*). FYPO_relaxed.owl CHEBI:60643 biolink:NamedThing NMDA receptor antagonist Any substance that inhibits the action of N-methyl-D-aspartate (NMDA) receptors. They tend to induce a state known as dissociative anesthesia, marked by catalepsy, amnesia, and analgesia, while side effects can include hallucinations, nightmares, and confusion. Due to their psychotomimetic effects, many NMDA receptor antagonists are used as recreational drugs. FYPO_relaxed.owl CHEBI:61049 biolink:NamedThing tacrolimus (anhydrous) A macrolide lactam containing a 23-membered lactone ring, originally isolated from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. FYPO_relaxed.owl CHEBI:61050 biolink:NamedThing alkyl hydroperoxide A peroxol R-OOH where the substituent R is an alkyl group. FYPO_relaxed.owl CHEBI:78673 biolink:NamedThing cumene hydroperoxide A peroxol that is cumene in which the alpha-hydrogen is replaced by a hydroperoxy group. FYPO_relaxed.owl CHEBI:61057 biolink:NamedThing tacrolimus hydrate A hydrate that is the monohydrate form of tacrolimus. FYPO_relaxed.owl CHEBI:61115 biolink:NamedThing EC 3.5.1.98 (histone deacetylase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC 3.5.1.98). FYPO_relaxed.owl CHEBI:76807 biolink:NamedThing EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor An EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor that interferes with the action of any non-peptide linear amide C-N hydrolase (EC 3.5.1.*). FYPO_relaxed.owl CHEBI:77941 biolink:NamedThing EC 3.5.1.4 (amidase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of amidase (EC 3.5.1.4). FYPO_relaxed.owl CHEBI:84264 biolink:NamedThing EC 3.5.1.19 (nicotinamidase) inhibitor An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the action of nicotinamidase (EC 3.5.1.19). FYPO_relaxed.owl CHEBI:84688 biolink:NamedThing Fe(III)-complexed hydroxamate siderophore Any iron(III) hydroxamate in which the hydroxamate component is a siderophore. FYPO_relaxed.owl CHEBI:61778 biolink:NamedThing triterpenoid saponin A terpene glycoside in which the terpene moiety is a triterpenoid. FYPO_relaxed.owl CHEBI:61951 biolink:NamedThing microtubule-destabilising agent Any substance that interacts with tubulin to inhibit polymerisation of microtubules. FYPO_relaxed.owl CHEBI:62237 biolink:NamedThing cardiolipin(2-) The organophosphate oxoanion that is the dianion formed from the phosphatidylglycerol cardiolipin by loss of an electron from each of the phospho groups. FYPO_relaxed.owl CHEBI:62434 biolink:NamedThing EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that interferes with the action of receptor protein-tyrosine kinase (EC 2.7.10.1). FYPO_relaxed.owl CHEBI:76617 biolink:NamedThing EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor An EC 2.7.10.* (protein-tyrosine kinase) inhibitor that specifically blocks the action of non-specific protein-tyrosine kinase (EC 2.7.10.2). FYPO_relaxed.owl CHEBI:62872 biolink:NamedThing EC 1.2.3.1 (aldehyde oxidase) inhibitor An EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor which interferes with the action of aldehyde oxidase (EC 1.2.3.1). FYPO_relaxed.owl CHEBI:76853 biolink:NamedThing EC 1.2.3.* (oxidoreductase acting on donor aldehyde/oxo group with oxygen as acceptor) inhibitor An EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.2.3.*). FYPO_relaxed.owl CHEBI:62913 biolink:NamedThing EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor An EC 2.4.2.* (pentosyltransferase) inhibitor that interferes with the action of a NAD(+) ADP-ribosyltransferase (EC 2.4.2.30). FYPO_relaxed.owl CHEBI:76790 biolink:NamedThing EC 2.4.2.* (pentosyltransferase) inhibitor An EC 2.4.* (glycosyltransferase) inhibitor that interferes with the action of any pentosyltransferase (EC 2.4.2.*). FYPO_relaxed.owl CHEBI:63070 biolink:NamedThing beta-alaninate A beta-amino-acid anion that is the conjugate base of beta-alanine. FYPO_relaxed.owl CHEBI:63156 biolink:NamedThing EC 1.1.3.13 (alcohol oxidase) inhibitor An EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor that interferes with the action of alcohol oxidase (EC 1.1.3.13). FYPO_relaxed.owl CHEBI:76836 biolink:NamedThing EC 1.1.3.* (oxidoreductase acting on donor CH-OH group, oxygen as acceptor) inhibitor An EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor that interferes with the action of any such enzyme using oxygen as acceptor (EC 1.1.3.*). FYPO_relaxed.owl CHEBI:63157 biolink:NamedThing EC 4.2.1.22 (cystathionine beta-synthase) inhibitor An EC 4.2.1.* (hydro-lyases) inhibitor that interferes with the action of cystathionine beta-synthase (EC 4.2.1.22). FYPO_relaxed.owl CHEBI:76907 biolink:NamedThing EC 4.2.1.* (hydro-lyases) inhibitor An EC 4.2.* (C-O lyase) inhibitor that interferes with the action of any hydro-lyase (EC 4.2.1.*). FYPO_relaxed.owl CHEBI:63384 biolink:NamedThing ketoheptose derivative A heptose derivative that is formally obtained from a ketoheptose. FYPO_relaxed.owl CHEBI:63441 biolink:NamedThing aldonic acid derivative A carbohydrate acid derivative that is formally obtained from an aldonic acid. FYPO_relaxed.owl CHEBI:64603 biolink:NamedThing diadenosyl polyphosphate A dinucleotide that consists of two adenosine moieties bridge by a chain of a variable number (from two to six) of phosphate units. FYPO_relaxed.owl CHEBI:64018 biolink:NamedThing protein kinase C agonist An agonist that selectively binds to and activates a protein kinase C receptor FYPO_relaxed.owl CHEBI:64090 biolink:NamedThing tert-butyl hydroperoxide An alkyl hydroperoxide in which the alkyl group is tert-butyl. It is widely used in a variety of oxidation processes. FYPO_relaxed.owl CHEBI:64133 biolink:NamedThing EC 2.5.1.58 (protein farnesyltransferase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of protein farnesyltransferase (EC 2.5.1.58), one of the three enzymes in the prenyltransferase group. FYPO_relaxed.owl CHEBI:76663 biolink:NamedThing EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor A transferase inhibitor that inhibits the transfer of an alkyl (other than methyl) or aryl group (EC 2.5.1.*). FYPO_relaxed.owl CHEBI:76797 biolink:NamedThing EC 2.5.1.18 (glutathione transferase) inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of a glutathione transferase (EC 2.5.1.18). FYPO_relaxed.owl CHEBI:85618 biolink:NamedThing EC 2.5.1.31 {ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]} inhibitor An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific]. FYPO_relaxed.owl CHEBI:64237 biolink:NamedThing EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins. FYPO_relaxed.owl CHEBI:64416 biolink:NamedThing EC 1.3.1.43 (arogenate dehydrogenase) inhibitor An EC 1.3.1.* (oxidoreductase acting on CH-CH group of donor, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of arogenate dehydrogenase (EC 1.3.1.43). FYPO_relaxed.owl CHEBI:76857 biolink:NamedThing EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor An EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.3.1.*). FYPO_relaxed.owl CHEBI:78377 biolink:NamedThing EC 1.3.1.8 [acyl-CoA dehydrogenase (NADP(+))] inhibitor An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of acyl-CoA dehydrogenase (NADP(+)), EC 1.3.1.8. FYPO_relaxed.owl CHEBI:83319 biolink:NamedThing EC 1.3.1.70 (Delta(14)-sterol reductase) inhibitor An EC 1.3.1.* (oxidoreductase acting on donor CH-CH group, NAD(+) or NADP(+) as acceptor) inhibitor that interferes with the action of Delta(14)-sterol reductase (EC 1.3.1.70). FYPO_relaxed.owl CHEBI:64570 biolink:NamedThing EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor An EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor that interferes with the action of glycine hydroxymethyltransferase (EC 2.1.2.1). FYPO_relaxed.owl CHEBI:76874 biolink:NamedThing EC 2.1.2.* (hydroxymethyl-, formyl- and related transferases) inhibitor An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any hydroxymethyl-, formyl- and related transferase (EC 2.1.2.*). FYPO_relaxed.owl CHEBI:64571 biolink:NamedThing NMDA receptor agonist An excitatory amino acid agonist which binds to NMDA receptors and triggers a response. FYPO_relaxed.owl CHEBI:64670 biolink:NamedThing EC 1.8.1.9 (thioredoxin reductase) inhibitor An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of thioredoxin reductase (EC 1.8.1.9). FYPO_relaxed.owl CHEBI:76869 biolink:NamedThing EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD(+) or NADP(+) as acceptor) inhibitor An EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor that interferes with the action of any such enzyme using NAD(+) or NADP(+) as acceptor (EC 1.8.1.*). FYPO_relaxed.owl CHEBI:77402 biolink:NamedThing EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor An EC 1.8.1.* (oxidoreductase acting on sulfur group of donors, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of trypanothione-disulfide reductase (EC 1.8.1.12). FYPO_relaxed.owl CHEBI:64763 biolink:NamedThing EC 3.1.4.11 (phosphoinositide phospholipase C) inhibitor An EC 3.1.4.* (phosphoric diester hydrolase) inhibitor that interferes with the action of phosphatidylinositol-specific phospholipase C (EC 3.1.4.11). FYPO_relaxed.owl CHEBI:64872 biolink:NamedThing 2-acyl-sn-glycero-3-phospho-1D-myo-inositol(1-) An anionic phospholipid obtained by deprotonation of the phosphate OH group of any 2-acyl-sn-glycero-3-phospho-D-myo-inositol; major species at pH 7.3. FYPO_relaxed.owl CHEBI:68498 biolink:NamedThing lysophosphatidyl-1D-myo-inositol(1-) An anionic phospholipid obtained by deprotonation of the phosphate OH group of any lysophosphatidyl-1D-myo-inositol; major species at pH 7.3. FYPO_relaxed.owl CHEBI:78233 biolink:NamedThing 2-acylglycero-3-phospho-1-inositol(1-) An anionic phospholipid that is the conjugate base of a 2-acylglycero-3-phospho-1-inositol; major species at pH 7.3. FYPO_relaxed.owl CHEBI:64947 biolink:NamedThing anti-HIV-1 agent An anti-HIV agent that destroys or inhibits the replication of HIV-1, the more infective and more virulent of the two types of HIV virus. FYPO_relaxed.owl CHEBI:64996 biolink:NamedThing EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor A lipoxygenase inhibitor that interferes with the action of arachidonate 15-lipoxygenase (EC 1.13.11.33). FYPO_relaxed.owl CHEBI:65053 biolink:NamedThing EC 4.1.1.19 (arginine decarboxylase) inhibitor An EC 4.1.1.* (carboxy-lyase) inhibitor that interferes with the action of arginine decarboxylase (EC 4.1.1.19). FYPO_relaxed.owl CHEBI:76906 biolink:NamedThing EC 4.1.1.* (carboxy-lyase) inhibitor An EC 4.1.* (C-C lyase) inhibitor that interferes with the action of any carboxy-lyase (EC 4.1.1.*). FYPO_relaxed.owl CHEBI:65064 biolink:NamedThing EC 2.1.1.79 (cyclopropane-fatty-acyl-phospholipid synthase) inhibitor An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of cyclopropane fatty acid synthase (EC 2.1.1.79). FYPO_relaxed.owl CHEBI:76871 biolink:NamedThing EC 2.1.1.* (methyltransferases) inhibitor An EC 2.1.* (C1-transferase) inhibitor that interferes with the action of any methyltransferase (EC 2.1.1.*). FYPO_relaxed.owl CHEBI:65065 biolink:NamedThing EC 2.1.1.72 [site-specific DNA-methyltransferase (adenine-specific)] inhibitor An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of site-specific DNA-methyltransferase (adenine-specific), EC 2.1.1.72. FYPO_relaxed.owl CHEBI:77115 biolink:NamedThing EC 2.1.1.122 [(S)-tetrahydroprotoberberine N-methyltransferase] inhibitor An EC 2.1.1.* (methyltransferases) inhibitor that interferes with the action of (S)-tetrahydroprotoberberine N-methyltransferase (EC 2.1.1.122). FYPO_relaxed.owl CHEBI:65102 biolink:NamedThing 3-hydroxy fatty acyl-CoA(4-) An acyl-CoA(4-) oxoanion arising from deprotonation of the phosphate and diphosphate OH groups of any 3-hydroxy fatty acyl-CoA; major species at pH 7.3. FYPO_relaxed.owl CHEBI:67040 biolink:NamedThing S-adenosyl-L-methioninate A sulfonium betaine that is a conjugate base of S-adenosyl-L-methionine obtained by the deprotonation of the carboxy group. FYPO_relaxed.owl CHEBI:67114 biolink:NamedThing ryanodine receptor agonist A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction. FYPO_relaxed.owl CHEBI:67202 biolink:NamedThing N,N'-(p-xylylidene)bis(aminoguanidine) dihydrochloride The hydrochloride salt of N,N'-(p-xylylidene)bis(aminoguanidine) [ratio HCl : N,N'-(p-xylylidene)bis(aminoguanidine) = 2:1]. FYPO_relaxed.owl CHEBI:84333 biolink:NamedThing synthalin A hydrochloride resulting from the reaction of decamethylenediguanidine with 2 mol eq. of hydrogen chloride. FYPO_relaxed.owl CHEBI:67274 biolink:NamedThing lysophosphatidylethanolamine zwitterion A zwitterion obtained by transfer of a proton from the phosphate to the amino group of any lysophosphatidylethanolamine. The structure is depicted in the image where R(1) = acyl, R(2) = H or where R(1) = H, R(2) = acyl. FYPO_relaxed.owl CHEBI:68508 biolink:NamedThing diethyl maleate A maleate ester resulting from the formal condensation of both carboxy groups of maleic acid with ethanol. A colourless liquid at room temperature (m.p. -10degreeC) with boiling point 220degreeC at 1 atm., it is commonly used as a dienophile for Diels-Alder-type cycloaddition reactions in organic synthesis. FYPO_relaxed.owl CHEBI:9642 biolink:NamedThing N-tosyl-L-phenylalanyl chloromethyl ketone The N-tosyl derivative of L-phenylalanyl chloromethyl ketone. FYPO_relaxed.owl CHEBI:76830 biolink:NamedThing EC 5.99.1.* (miscellaneous isomerase) inhibitor An EC 5.99.* (other isomerases) inhibitor that interferes with the activity of any enzyme in the EC 5.99.1.* class. FYPO_relaxed.owl CHEBI:71181 biolink:NamedThing Sir2 inhibitor An EC 3.5.1.98 (histone deacetylase) inhibitor that interferes with the action of Sir2. FYPO_relaxed.owl CHEBI:71543 biolink:NamedThing rotenoid Members of the class of tetrahydrochromenochromene that consists of a cis-fused tetrahydrochromeno[3,4-b]chromene skeleton and its substituted derivatives. The term was originally restricted to natural products, but is now also used to describe semi-synthetic and fully synthetic compounds. FYPO_relaxed.owl CHEBI:71300 biolink:NamedThing EC 2.* (transferase) inhibitor An enzyme inhibitor that inhibits the action of a transferase (EC 2.*) FYPO_relaxed.owl CHEBI:75596 biolink:NamedThing EC 5.* (isomerase) inhibitor An enzyme inhibitor that inhibits the action of an isomerase (EC 5.*.*.*). FYPO_relaxed.owl CHEBI:75603 biolink:NamedThing EC 6.* (ligase) inhibitor Any enzyme inhibitor that interferes with the action of a ligase (EC 6.*.*.*). Ligases are enzymes that catalyse the joining of two molecules with concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. FYPO_relaxed.owl CHEBI:76710 biolink:NamedThing EC 4.* (lyase) inhibitor An enzyme inhibitor which interferes with the action of a lyase (EC 4.*.*.*). Lyases are enzymes cleaving C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation. FYPO_relaxed.owl CHEBI:76725 biolink:NamedThing EC 1.* (oxidoreductase) inhibitor An enzyme inhibitor which interferes with the action of an oxidoreductase (EC 1.*.*.*). FYPO_relaxed.owl CHEBI:72579 biolink:NamedThing tetrahydrochromenochromene Any chromenochromene resulting from the formal cis-fusion of two dihydro chromene rings, together with their substituted derivatives. FYPO_relaxed.owl CHEBI:73398 biolink:NamedThing indole skeleton A mancude heterobicyclic organic group consisting of a benzene ring fused to a pyrrole ring. FYPO_relaxed.owl CHEBI:73541 biolink:NamedThing organic heterobicyclic ring A bicyclic organic group that contains both carbon and hetero atoms. FYPO_relaxed.owl CHEBI:74213 biolink:NamedThing EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that inhibits the action of ribonucleoside-diphosphate reductase (EC 1.17.4.1). FYPO_relaxed.owl CHEBI:76848 biolink:NamedThing EC 1.17.4.* (oxidoreductase acting on CH or CH2 with a disulfide as acceptor) inhibitor An EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor that interferes with the activity of any such enzyme that uses a disulfide as acceptor (EC 1.17.4.*). FYPO_relaxed.owl CHEBI:74529 biolink:NamedThing antidote to paracetamol poisoning A role borne by a molecule that acts to counteract or neutralize the deleterious effects of paracetamol (acetaminophen). FYPO_relaxed.owl CHEBI:74530 biolink:NamedThing antidote to curare poisoning A role borne by a molecule that acts to counteract or neutralize the deleterious effects of curare. FYPO_relaxed.owl CHEBI:75190 biolink:NamedThing EC 5.4.3.2 (lysine 2,3-aminomutase) inhibitor An EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor that interferes with the action of lysine 2,3-aminomutase (EC 5.4.3.2). FYPO_relaxed.owl CHEBI:76829 biolink:NamedThing EC 5.4.3.* (intramolecular transferase transferring amino groups) inhibitor An EC 5.4.* (intramolecular transferase) inhibitor that interferes with the activity of any intramolecular transferase transferring amino groups (EC 5.4.3.*). FYPO_relaxed.owl CHEBI:75253 biolink:NamedThing phenylarsine oxide An arsine oxide derived from phenylarsine. FYPO_relaxed.owl CHEBI:75282 biolink:NamedThing ergosterol biosynthesis inhibitor Any compound that inhibits one or more steps in the pathway leading to the synthesis of ergosterol. FYPO_relaxed.owl CHEBI:75380 biolink:NamedThing EC 1.11.1.6 (catalase) inhibitor An inhibitor of peroxidases (EC 1.11.1.*) that inhibits the action of catalase (EC 1.11.1.6). FYPO_relaxed.owl CHEBI:75381 biolink:NamedThing EC 1.11.1.* (peroxidases) inhibitor An EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor that interferes with the action of any of the peroxidases (EC 1.11.1.*). FYPO_relaxed.owl CHEBI:76738 biolink:NamedThing EC 1.11.* (oxidoreductase acting on peroxide as donors) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on peroxide as donors (EC 1.11.*.*). FYPO_relaxed.owl CHEBI:75600 biolink:NamedThing EC 6.3.* (C-N bond-forming ligase) inhibitor A ligase inhibitor that interferes with the action of a C-N bond-forming ligase (EC 6.3.*.*). FYPO_relaxed.owl CHEBI:75767 biolink:NamedThing animal metabolite Any eukaryotic metabolite produced during a metabolic reaction in animals that include diverse creatures from sponges, insects to mammals. FYPO_relaxed.owl CHEBI:84735 biolink:NamedThing algal metabolite Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae. FYPO_relaxed.owl CHEBI:75768 biolink:NamedThing mammalian metabolite Any animal metabolite produced during a metabolic reaction in mammals. FYPO_relaxed.owl CHEBI:83039 biolink:NamedThing crustacean metabolite An animal metabolite produced by arthropods such as crabs, lobsters, crayfish, shrimps and krill. FYPO_relaxed.owl CHEBI:75771 biolink:NamedThing mouse metabolite Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus). FYPO_relaxed.owl CHEBI:77746 biolink:NamedThing human metabolite Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens). FYPO_relaxed.owl CHEBI:76282 biolink:NamedThing suberate(2-) A dicarboxylic acid dianion obtained by deprotonation of both carboxy groups of suberic acid; major species at pH 7.3. FYPO_relaxed.owl CHEBI:76655 biolink:NamedThing EC 2.1.* (C1-transferase) inhibitor A transferase inhibitor inhibiting the action of transferase of a one-carbon-containing group (EC 2.1.*.*). FYPO_relaxed.owl CHEBI:76661 biolink:NamedThing EC 2.3.* (acyltransferase) inhibitor A transferase inhibitor that interferes with the action of an acyltransferase (EC 2.3.*.*). FYPO_relaxed.owl CHEBI:76662 biolink:NamedThing EC 2.4.* (glycosyltransferase) inhibitor A transferase inhibitor inhibiting the action of a glycosyltransferase (EC 2.4.*.*). FYPO_relaxed.owl CHEBI:76834 biolink:NamedThing EC 2.5.* (non-methyl-alkyl or aryl transferase) inhibitor An EC 2.5.* (transferase) inhibitor that inhibits the action of any transferase that transfers an alkyl (other than methyl) or aryl group (EC 2.5.*). FYPO_relaxed.owl CHEBI:76694 biolink:NamedThing EC 5.3.* (intramolecular oxidoreductase) inhibitor An isomerase inhibitor that interferes with the action of an intramolecular oxidoreductase (EC 5.3.*.*). FYPO_relaxed.owl CHEBI:76695 biolink:NamedThing EC 5.4.* (intramolecular transferase) inhibitor An isomerase inhibitor that interferes with the action of an intramolecular transferase (EC 5.4.*.*). FYPO_relaxed.owl CHEBI:76697 biolink:NamedThing EC 5.99.* (other isomerases) inhibitor An isomerase inhibitor that interferes with the action of any member of the group of 'other isomerases' (EC 5.99.*.*). FYPO_relaxed.owl CHEBI:76711 biolink:NamedThing EC 4.1.* (C-C lyase) inhibitor A lyase inhibitor which inhibits the action of a C-C lyase (EC 4.1.*.*). FYPO_relaxed.owl CHEBI:76712 biolink:NamedThing EC 4.2.* (C-O lyase) inhibitor A lyase inhibitor which inhibits the action of a C-O lyase (EC 4.2.*.*). FYPO_relaxed.owl CHEBI:76713 biolink:NamedThing EC 4.3.* (C-N lyase) inhibitor A lyase inhibitor which inhibits the action of a C-N lyase (EC 4.3.*.*). FYPO_relaxed.owl CHEBI:76726 biolink:NamedThing EC 1.1.* (oxidoreductase acting on donor CH-OH group) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-OH group of donors (EC 1.1.*.*). FYPO_relaxed.owl CHEBI:76727 biolink:NamedThing EC 1.2.* (oxidoreductase acting on donor aldehyde/oxo group) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the aldehyde or oxo group of donors (EC 1.2.*.*). FYPO_relaxed.owl CHEBI:76729 biolink:NamedThing EC 1.3.* (oxidoreductase acting on donor CH-CH group) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-CH group of donors (EC 1.3.*.*). FYPO_relaxed.owl CHEBI:76731 biolink:NamedThing EC 1.5.* (oxidoreductase acting on donor CH-NH group) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on the CH-NH group of donors (EC 1.5.*.*). FYPO_relaxed.owl CHEBI:76733 biolink:NamedThing EC 1.6.* (oxidoreductase acting on NADH or NADPH) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on NADH or NADPH (EC 1.6.*.*). FYPO_relaxed.owl CHEBI:76735 biolink:NamedThing EC 1.8.* (oxidoreductase acting on sulfur group of donors) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase of class EC 1.8.*.* (acting on a sulfur group of donors). FYPO_relaxed.owl CHEBI:76736 biolink:NamedThing EC 1.9.* (oxidoreductase acting on donor heme group) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on a heme group of donors (EC 1.9.*.*). FYPO_relaxed.owl CHEBI:76740 biolink:NamedThing EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases), EC 1.13.*.*. FYPO_relaxed.owl CHEBI:76741 biolink:NamedThing EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on hydrogen as donors (EC 1.14.*.*). FYPO_relaxed.owl CHEBI:76744 biolink:NamedThing EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor An oxidoreductase inhibitor which interferes with the action of an oxidoreductase acting on CH or CH2 (EC 1.17.*.*). FYPO_relaxed.owl CHEBI:76832 biolink:NamedThing EC 4.3.1.* (ammonia-lyase) inhibitor An EC 4.3.* (C-N lyase) inhibitor that interferes with the action of any ammonia-lyase (EC 4.3.1.*). FYPO_relaxed.owl CHEBI:76838 biolink:NamedThing EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor An EC 1.14.* (oxidoreductase acting on paired donors, with incorporation or reduction of molecular oxygen) inhibitor that interferes with the action of any such enzyme incorporating one atom of oxygen and using reduced flavin or flavoprotein as donor (EC 1.14.14.*). FYPO_relaxed.owl CHEBI:76967 biolink:NamedThing human xenobiotic metabolite Any human metabolite produced by metabolism of a xenobiotic compound in humans. FYPO_relaxed.owl CHEBI:83399 biolink:NamedThing marine xenobiotic metabolite Any metabolite produced by metabolism of a xenobiotic compound in marine macro- and microorganisms. FYPO_relaxed.owl CHEBI:84087 biolink:NamedThing human urinary metabolite Any metabolite (endogenous or exogenous) found in human urine samples. FYPO_relaxed.owl CHEBI:85234 biolink:NamedThing human blood serum metabolite Any metabolite (endogenous or exogenous) found in human blood serum samples. FYPO_relaxed.owl CHEBI:76979 biolink:NamedThing 1,2-dioctanoyl-sn-glycerol 1,2-diacyl-sn-glycerol in which both the 1- and 2-acyl groups are specified as octanoyl. Formula C19H36O5. FYPO_relaxed.owl CHEBI:76982 biolink:NamedThing 2,3-dioctanoyl-sn-glycerol A 2,3-diacyl-sn-glycerol in which both the 2- and 3-acyl groups are specified as octanoyl. FYPO_relaxed.owl CHEBI:76988 biolink:NamedThing xenoestrogen A synthetic or semi-synthetic compound that has oestrogenic activity. FYPO_relaxed.owl CHEBI:76990 biolink:NamedThing mycoestrogen Any compound produced by a fungus that happens to have estrogenic activity. FYPO_relaxed.owl CHEBI:77090 biolink:NamedThing EC 4.3.1.10 (serine-sulfate ammonia-lyase) inhibitor An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of serine-sulfate ammonia-lyase (EC 4.3.1.10). FYPO_relaxed.owl CHEBI:77703 biolink:NamedThing EC 4.3.1.3 (histidine ammonia-lyase) inhibitor An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of histidine ammonia-lyase (EC 4.3.1.3). FYPO_relaxed.owl CHEBI:77881 biolink:NamedThing EC 4.3.1.15 (diaminopropionate ammonia-lyase) inhibitor An EC 4.3.1.* (ammonia-lyase) inhibitor that interferes with the action of diaminopropionate ammonia-lyase (EC 4.3.1.15). FYPO_relaxed.owl CHEBI:77255 biolink:NamedThing EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor An EC 3.4.24.* (metalloendopeptidase) inhibitor that interferes with the action of anthrax lethal factor endopeptidase (EC 3.4.24.83). FYPO_relaxed.owl CHEBI:78597 biolink:NamedThing N-terminal alpha-amino-acid(1+) residue An alpha-amino-acid cation residue obtained by protonation of the amino function of any N-terminal alpha-amino-acid residue; major species at pH 7.3. FYPO_relaxed.owl CHEBI:78682 biolink:NamedThing D-fructose 1,6-bisphosphate A ketohexose bisphosphate that is D-fructose substituted by phosphate groups at positions 1 and 6. It is an intermediate in the glycolysis metabolic pathway. FYPO_relaxed.owl CHEBI:81667 biolink:NamedThing 2-hydroxy-5-methylquinone A member of the class of monohydroxy-1,4-benzoquinones that is 2-hydroxy-1,4-benzoquinone carrying an additional methyl substituent at position 5. FYPO_relaxed.owl CHEBI:87067 biolink:NamedThing conazole fungicide Any conazole antifungal agent that has been used as a fungicide. FYPO_relaxed.owl CHEBI:87100 biolink:NamedThing triazole fungicide Any triazole antifungal agent that has been used as a fungicide. FYPO_relaxed.owl CHEBI:82872 biolink:NamedThing (S)-econazole A 1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole that is the (S)-enantiomer of econazole. FYPO_relaxed.owl CHEBI:82877 biolink:NamedThing (R)-econazole A 1-{2-(4-chlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl}imidazole that is the (R)-enantiomer of econazole. FYPO_relaxed.owl CHEBI:82894 biolink:NamedThing (R)-miconazole A 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole that has R configuration. FYPO_relaxed.owl CHEBI:82897 biolink:NamedThing (S)-miconazole A 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]imidazole that has S) configuration. FYPO_relaxed.owl CHEBI:82980 biolink:NamedThing (2R,4S)-terconazole A 1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine in which positions 2 and 4 of the 1,3-dioxolane moiety have R and S configuration, respectively. FYPO_relaxed.owl CHEBI:82981 biolink:NamedThing (2S,4R)-terconazole A 1-(4-{[2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)-4-isopropylpiperazine in which positions 2 and 4 of the 1,3-dioxolane moiety have S and R configuration, respectively. FYPO_relaxed.owl CHEBI:83038 biolink:NamedThing Daphnia galeata metabolite A Daphnia metabolite produced by the species Daphnia galeata. FYPO_relaxed.owl CHEBI:83057 biolink:NamedThing Daphnia metabolite A crustacean metabolite produced by the genus of small planktonic arthropods, Daphnia FYPO_relaxed.owl CHEBI:83056 biolink:NamedThing Daphnia magna metabolite A Daphnia metabolite produced by the species Daphnia magna. FYPO_relaxed.owl CHEBI:83146 biolink:NamedThing Daphnia tenebrosa metabolite A Daphnia metabolite produced by the species Daphnia tenebrosa. FYPO_relaxed.owl CHEBI:83243 biolink:NamedThing 1-stearoyl-2-arachidonoyl-sn-glycero-3-phospho-(1D-myo-inositol 3,4,5-triphosphate)(7-) A 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-) in which the phosphatidyl acyl groups at positions 1 and 2 are specified as stearoyl and arachidonoyl respectively. FYPO_relaxed.owl CHEBI:83629 biolink:NamedThing tea tree oil An essential oil consisting of approximately one hundred hydrocarbon and terpenoid components obtained by steam distillation from the leaves and terminal branchlets of the tea tree, Melaleuca alternifolia; the yield of oil is typically 1-2% of wet plant material weight. The main components are 4-terpineol (40%), gamma-terpinene (23%), alpha-terpinene (10%), 1,8-cineole (5%), terpinolene (3%), and p-cymene (3%). FYPO_relaxed.owl CHEBI:83780 biolink:NamedThing (S)-tebuconazole The (S)-enantiomer of 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol. FYPO_relaxed.owl CHEBI:83781 biolink:NamedThing (R)-tebuconazole The (R)-enantiomer of 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol. FYPO_relaxed.owl CHEBI:84058 biolink:NamedThing ophthalmic acid A L-glutamine derivative that is L-glutamine substituted by a 1-[(carboxymethyl)amino]-1-oxobutan-2-yl at the terminal amino nitrogen atom. FYPO_relaxed.owl CHEBI:84139 biolink:NamedThing myo-inositol phosphate(2-) An inositol phosphate oxoanion resulting from the removal of both of the protons from the phosphate group of a myo-inositol monophosphate. FYPO_relaxed.owl CHEBI:85046 biolink:NamedThing skin lightening agent Any cosmetic used to lighten the colour of skin by reducing the concentration of melanin. FYPO_relaxed.owl CHEBI:85613 biolink:NamedThing 2-bromo-2-{[(4-methylphenyl)sulfonyl]methyl}-1-indanone A member of the class of indanones that is 1-indanone substituted at position 2 by bromo and [(4-methylphenyl)sulfonyl]methyl groups. FYPO_relaxed.owl CHEBI:86383 biolink:NamedThing EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor An EC 5.3.* (intramolecular oxidoreductase) inhibitor that inhibits the action of any such enzyme that transposes C=C bonds (EC 5.3.3.*). FYPO_relaxed.owl CHEBI:86385 biolink:NamedThing EC 5.3.3.5 (cholestenol Delta-isomerase) inhibitor An EC 5.3.3.* (intramolecular oxidase transposing C=C bonds) inhibitor that interferes with the action of a cholestenol Delta-isomerase (EC 5.3.3.5). FYPO_relaxed.owl CHEBI:88685 biolink:NamedThing 1-(11Z)-icosenoyl-sn-glycero-3-phosphocholine A 1-icosenoyl-sn-glycero-3-phosphocholine in which the the double bond of the icosenoyl group is at the 11-12 position and has Z configuration. FYPO_relaxed.owl CHEBI:88868 biolink:NamedThing Phenylglyoxal FYPO_relaxed.owl CHEBI:9457 biolink:NamedThing terpinolene A p-menthadiene with double bonds at positions 1 and 4(8). FYPO_relaxed.owl CHEBI:9602 biolink:NamedThing Tingenone FYPO_relaxed.owl CHEBI:9620 biolink:NamedThing tolnaftate A monothiocarbamic ester that is the methyl(3-tolyl)carbamothioate ester of 2-naphthol. A synthetic anti-fungal agent used to treat jock itch, athlete's foot and ringworm. FYPO_relaxed.owl CL:0000000 biolink:NamedThing cell A material entity of anatomical origin (part of or deriving from an organism) that has as its parts a maximally connected cell compartment surrounded by a plasma membrane. FYPO_relaxed.owl CL:0000225 biolink:NamedThing anucleate cell A cell that lacks a nucleus. FYPO_relaxed.owl CL:0000226 biolink:NamedThing single nucleate cell A cell with a single nucleus. FYPO_relaxed.owl CL:0000227 biolink:NamedThing binucleate cell FYPO_relaxed.owl CL:0000228 biolink:NamedThing multinucleate cell A cell with more than one nucleus. FYPO_relaxed.owl CL:0001061 biolink:NamedThing abnormal cell A cell found in an organism or derived from an organism exhibiting a phenotype that deviates from the expected phenotype of any native cell type of that organism. Abnormal cells are typically found in disease states or disease models. FYPO_relaxed.owl CL:0002242 biolink:NamedThing nucleate cell A cell containing at least one nucleus. FYPO_relaxed.owl CL:0000154 biolink:NamedThing protein secreting cell FYPO_relaxed.owl CL:0000334 biolink:NamedThing vegetative cell (sensu Fungi) FYPO_relaxed.owl CL:0000521 biolink:NamedThing fungal cell FYPO_relaxed.owl CL:0002369 biolink:NamedThing fungal spore A differentiated form of a fungus produced during or as a result of an asexual or sexual reproductive process; usually a cell with a thick cell wall that stores and protects one or more nuclei. Spores may be produced in response to, and are characteristically resistant to, adverse environmental conditions. FYPO_relaxed.owl CL:0002674 biolink:NamedThing H minus A S. pombe mating type determined by the mat1-Mc and mat1-Mi on the mat1 locus. FYPO_relaxed.owl CL:0002675 biolink:NamedThing H plus A S. pombe cell type determined by mat1-Pc and mat1-Pi on the mat1 locus. FYPO_relaxed.owl CL:0000255 biolink:NamedThing eukaryotic cell FYPO_relaxed.owl CL:0000596 biolink:NamedThing sexual spore A spore formed following meiosis. Sometimes following meiosis, prospores may undergo one or more rounds of mitosis before they are fully mature. FYPO_relaxed.owl CL:0017505 biolink:NamedThing increased nucleus size A nucleus size quality which is relatively high compared to the amount of cytoplasm present in the same cell. FYPO_relaxed.owl GO:0005634 biolink:NamedThing nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. FYPO_relaxed.owl GO:1905754 biolink:NamedThing ascospore-type prospore nucleus Any nucleus that is part of a ascospore-type prospore. FYPO_relaxed.owl FYPO:0000002 biolink:NamedThing cell phenotype A phenotype that is observed at the level of an individual cell. FYPO_relaxed.owl FYPO:0000001 biolink:NamedThing phenotype Any of the set of observable characteristics of an organism resulting from the interaction of its genotype with the environment. FYPO_relaxed.owl FYPO:0000003 biolink:NamedThing cell population phenotype A phenotype that is observed at the level of a population of cells. FYPO_relaxed.owl FYPO:0000257 biolink:NamedThing normal phenotype A phenotype that shows no detectable differences from normal. In fission yeast, the characteristics of wild type cells of the sequenced strain (972 h-) or the isogenic h+ or h90 strains are regarded as normal. FYPO_relaxed.owl FYPO:0000300 biolink:NamedThing biological process phenotype A phenotype that affects a biological process. FYPO_relaxed.owl FYPO:0000652 biolink:NamedThing molecular function phenotype A phenotype that affects a molecular function such as binding or catalytic activity. FYPO_relaxed.owl FYPO:0001985 biolink:NamedThing abnormal phenotype A phenotype that shows detectable differences from normal. In fission yeast, the characteristics of wild type cells of the sequenced strain (972 h-) or the isogenic h+ or h90 strains are regarded as normal. FYPO_relaxed.owl FYPO:0000004 biolink:NamedThing cell viability A cell phenotype that consists of the cell's disposition to survive and develop normally. FYPO_relaxed.owl FYPO:0000136 biolink:NamedThing cellular physical quality phenotype A phenotype that affects any physical object quality, such as morphology, number, location, etc., of a cell or a cellular component. FYPO_relaxed.owl FYPO:0000128 biolink:NamedThing auxotrophy A phenotype in which a cell requires a particular organic compound, which is not required by a wild-type cell for its growth. Auxotrophy usually results from a cell's inability to synthesize the compound. FYPO_relaxed.owl FYPO:0001321 biolink:NamedThing cellular physical quality phenotype during vegetative growth A phenotype that affects any physical object quality, such as morphology, number, location, etc., of a cell or a cellular component in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0002069 biolink:NamedThing mislocalized nucleus A physical cellular phenotype in which a cell has a nucleus in an abnormal location. The normal location is at the midpoint of the long axis of the cell. FYPO_relaxed.owl FYPO:0002731 biolink:NamedThing mononucleate A physical cellular phenotype in which a cell contains a single nucleus. FYPO_relaxed.owl FYPO:0003546 biolink:NamedThing increased DNA damage A cell phenotype in which the amount of DNA damage measured in a cell is greater than normal. The number, extent, or both of damage sites may be increased. FYPO_relaxed.owl FYPO:0004638 biolink:NamedThing abnormal cellular physical quality phenotype A phenotype in which any physical object quality, such as morphology, number, location, etc., of a cell or a cellular component is abnormal. FYPO_relaxed.owl FYPO:0006420 biolink:NamedThing normal duration of Rad51 focus presence during meiotic cell cycle A cell phenotype in which sites at which the protein Rad51 accumulates remain present for a normal (i.e. indistinguishable from wild type) amount of time during the meiotic cell cycle. Normally, Rad51 foci form during prophase I but disappear before metaphase I. FYPO_relaxed.owl FYPO:0006771 biolink:NamedThing mislocalized actin cortical patches A physical cellular phenotype in which a cell has actin cortical patches in one or more abnormal locations. FYPO_relaxed.owl FYPO:0007723 biolink:NamedThing normal cellular physical quality phenotype A phenotype in which a physical object quality, such as morphology, number, location, etc., of a cell or a cellular component is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0009108 biolink:NamedThing abnormal spindle pole body orientation during mitotic telophase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the spindle pole bodies (SPBs) of daughter nuclei are misoriented during mitotic telophase. Normally, SPBs face the cell tips at the end of anaphase when the spindle disassembles, but as microtubules are nucleated from SPBs and telophase nuclear positioning proceeds, the SPBs tend to face the cell equator. FYPO_relaxed.owl FYPO:0000005 biolink:NamedThing abnormal cell morphology A cell phenotype characterized by altered cell morphology, i.e. the size, shape, or structure of the cell is abnormal. FYPO_relaxed.owl FYPO:0003037 biolink:NamedThing abnormal cell phenotype A phenotype that shows detectable differences from normal at the level of an individual cell. In fission yeast, the characteristics of wild type cells of the sequenced strain (972 h-) or the isogenic h+ or h90 strains are regarded as normal. FYPO_relaxed.owl FYPO:0000628 biolink:NamedThing abnormal cellular process A phenotype in which a specific cellular process is abnormal. FYPO_relaxed.owl FYPO:0000989 biolink:NamedThing altered level of substance in cell A cell phenotype in which the amount of a specific substance measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0001859 biolink:NamedThing increased minichromosome loss A cell phenotype in which minichromosomes are lost at a higher frequency than normal. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation. FYPO_relaxed.owl FYPO:0003038 biolink:NamedThing abnormal RNA stability A cell phenotype in which RNA stability is abnormal. RNA molecules may be more or less likely to degrade over a given time period than in wild type. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0003452 biolink:NamedThing mislocalized protein A cell phenotype in which a protein is observed in a particular location where it is not normally found. FYPO_relaxed.owl FYPO:0003755 biolink:NamedThing abnormal vegetative cell phenotype A phenotype that shows detectable differences from normal at the level of an individual cell, when the cell is in the vegetative growth phase of the cell cycle. In fission yeast, the characteristics of wild type cells of the sequenced strain (972 h-) or the isogenic h+ or h90 strains are regarded as normal. FYPO_relaxed.owl FYPO:0003846 biolink:NamedThing spores sensitive to acetone A cell phenotype in which spores germinate to a lower extent than wild type following exposure to acetone. FYPO_relaxed.owl FYPO:0003879 biolink:NamedThing delayed onset of age-related vacuolar changes A cell phenotype in which changes in vacuolar morphology or function associated with cell aging begin later than normal. As cells age, vacuoles become fragmented and vacuolar acidity decreases. In a mutant, these changes may occur to a lesser extent as well as later than in wild type. FYPO_relaxed.owl FYPO:0003929 biolink:NamedThing spores sensitive to ionizing radiation A cell phenotype in which spores germinate to a lower extent than wild type following exposure to ionizing radiation. FYPO_relaxed.owl FYPO:0004782 biolink:NamedThing spores resistant to ionizing radiation A cell phenotype in which spores germinate to a greater extent than wild type following exposure to ionizing radiation. FYPO_relaxed.owl FYPO:0005130 biolink:NamedThing spores sensitive to heat A cell phenotype in which spores germinate to a lower extent than wild type following exposure to heat. FYPO_relaxed.owl FYPO:0005131 biolink:NamedThing spores sensitive to ethanol A cell phenotype in which spores germinate to a lower extent than wild type following exposure to ethanol. FYPO_relaxed.owl FYPO:0005132 biolink:NamedThing spores sensitive to cell wall-degrading enzymes A cell phenotype in which spores germinate to a lower extent than wild type following exposure to an enzymes that degrades cell wall polysaccharides. FYPO_relaxed.owl FYPO:0005453 biolink:NamedThing abolished break-induced loss of heterozygosity via chromosomal translocation A cell phenotype observed in the vegetative growth phase of the life cycle in which chromosomal translocation that would result in the loss of one of two different alleles of a gene does not occur. FYPO_relaxed.owl FYPO:0000035 biolink:NamedThing growth auxotrophic for arginine Auxotrophy in which a cell is unable to synthesize arginine, and therefore requires arginine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0000036 biolink:NamedThing growth auxotrophic for asparagine Auxotrophy in which a cell is unable to synthesize asparagine, and therefore requires asparagine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0000038 biolink:NamedThing growth auxotrophic for ethanolamine Auxotrophy in which a cell is unable to synthesize ethanolamine, and therefore requires ethanolamine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0000039 biolink:NamedThing growth auxotrophic for lysine Auxotrophy in which a cell is unable to synthesize lysine, and therefore requires lysine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0000041 biolink:NamedThing growth auxotrophic for phenylalanine Auxotrophy in which a cell is unable to synthesize phenylalanine, and therefore requires phenylalanine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0000246 biolink:NamedThing growth auxotrophic for antioxidant A cell population phenotype in which a cell population grows only in the presence of an antioxidant in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000287 biolink:NamedThing abnormal subcellular component A physical cellular phenotype in which the amount, distribution, composition or morphology of a cell part is abnormal. FYPO_relaxed.owl FYPO:0000369 biolink:NamedThing vacuoles absent A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells do not contain vacuoles. FYPO_relaxed.owl FYPO:0000635 biolink:NamedThing growth auxotrophic for leucine Auxotrophy in which a cell is unable to synthesize leucine, and therefore requires leucine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0000747 biolink:NamedThing growth auxotrophic for adenine Auxotrophy in which a cell is unable to synthesize adenine, and therefore requires adenine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0000949 biolink:NamedThing aseptate A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell does not contain a septum. FYPO_relaxed.owl FYPO:0001012 biolink:NamedThing growth auxotrophic for uracil Auxotrophy in which a cell is unable to synthesize uracil, and therefore requires uracil in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0001907 biolink:NamedThing growth auxotrophic for thiamine Auxotrophy in which a cell is unable to synthesize thiamine, and therefore requires thiamine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0002068 biolink:NamedThing growth auxotrophic for histidine Auxotrophy in which a cell is unable to synthesize histidine, and therefore requires histidine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0002271 biolink:NamedThing growth auxotrophic for glutamine Auxotrophy in which a cell is unable to synthesize glutamine, and therefore requires glutamine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0002787 biolink:NamedThing small vacuoles A cell phenotype in which vacuoles are smaller than normal. FYPO_relaxed.owl FYPO:0002790 biolink:NamedThing vacuoles present in increased numbers A physical cellular phenotype in which cells contain more vacuoles than normal. FYPO_relaxed.owl FYPO:0002793 biolink:NamedThing vacuoles present in decreased numbers during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer vacuoles than normal. FYPO_relaxed.owl FYPO:0002794 biolink:NamedThing abnormal vacuole A physical cellular phenotype in which the number, distribution, or morphology of all or part of the vacuole(s) is abnormal. FYPO_relaxed.owl FYPO:0003355 biolink:NamedThing growth auxotrophic for sulfur-containing amino acid Auxotrophy in which a cell is unable to synthesize sulfur-containing amino acids, and therefore requires one or more sulfur-containing amino acids (e.g. cysteine or methionine) in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0003367 biolink:NamedThing growth auxotrophic for pyridoxine Auxotrophy in which a cell is unable to synthesize pyridoxine, and therefore requires pyridoxine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0004107 biolink:NamedThing normal protein level during mitotic G2 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G2 phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004555 biolink:NamedThing growth auxotrophic for choline Auxotrophy in which a cell is unable to synthesize choline, and therefore requires choline in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0004639 biolink:NamedThing abnormal cellular physical quality phenotype during vegetative growth A phenotype observed in the vegetative growth phase of the life cycle in which any physical object quality, such as morphology, number, location, etc., of a cell or a cellular component is abnormal. FYPO_relaxed.owl FYPO:0004708 biolink:NamedThing decreased cytosolic large:small ribosomal subunit ratio A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the ratio of large to small ribosomal subunits present in the cytosol is lower than normal.. FYPO_relaxed.owl FYPO:0004709 biolink:NamedThing increased number of Rad52 foci A cell phenotype in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal. FYPO_relaxed.owl FYPO:0005575 biolink:NamedThing growth auxotrophic for magnesium Auxotrophy in which a cell requires magnesium ions in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0005875 biolink:NamedThing growth auxotrophic for proline Auxotrophy in which a cell is unable to synthesize proline, and therefore requires proline in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0005876 biolink:NamedThing growth auxotrophic for tyrosine Auxotrophy in which a cell is unable to synthesize tyrosine, and therefore requires tyrosine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0005877 biolink:NamedThing growth auxotrophic for glutamate Auxotrophy in which a cell is unable to synthesize glutamate, and therefore requires glutamate in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0005878 biolink:NamedThing growth auxotrophic for tryptophan Auxotrophy in which a cell is unable to synthesize tryptophan, and therefore requires tryptophan in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0006053 biolink:NamedThing lipid droplets present in spore cytoplasm in decreased numbers, mislocalized to ascus epiplasm A physical cellular phenotype in which the spore cytoplasm contains fewer lipid droplets than normal. Some lipid droplets are present in the ascus epiplasm instead. FYPO_relaxed.owl FYPO:0006160 biolink:NamedThing decreased number of Rad51 foci during meiotic prophase I A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad51 accumulates is lower than normal during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006419 biolink:NamedThing increased duration of Rad51 focus presence during meiotic cell cycle A cell phenotype in which sites at which the protein Rad51 accumulates remain present for longer than normal during the meiotic cell cycle. Normally, Rad51 foci form during prophase I but disappear before metaphase I. FYPO_relaxed.owl FYPO:0006784 biolink:NamedThing tubular vacuole morphology during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which vacuoles tubule-shaped. FYPO_relaxed.owl FYPO:0007105 biolink:NamedThing increased duration of Rad52 focus presence during meiotic cell cycle A cell phenotype in which sites at which the protein Rad52 accumulates remain present for a longer time than normal during the meiotic cell cycle. Normally, Rad52 foci form during prophase I but disappear before metaphase I. FYPO_relaxed.owl FYPO:0007207 biolink:NamedThing growth auxotrophic for aspartate Auxotrophy in which a cell is unable to synthesize aspartate, and therefore requires aspartate in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0007355 biolink:NamedThing increased number of Smp foci A cell phenotype in which the cell contains more Smp foci than normal. FYPO_relaxed.owl FYPO:0007686 biolink:NamedThing increased number of nuclear exosome foci A cell phenotype in which the cell contains more nuclear exosome foci than normal. FYPO_relaxed.owl FYPO:0007990 biolink:NamedThing growth auxotrophic for isoleucine Auxotrophy in which a cell is unable to synthesize isoleucine, and therefore requires isoleucine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0007991 biolink:NamedThing growth auxotrophic for valine Auxotrophy in which a cell is unable to synthesize valine, and therefore requires leucine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0008094 biolink:NamedThing increased number of Rpa2 foci during vegetative growth A cell phenotype in which the number of sites at which the protein Rpa2 accumulates is greater than normal during vegetative growth. FYPO_relaxed.owl FYPO:0008163 biolink:NamedThing increased number of nuclear foci A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of nuclear foci are increased. FYPO_relaxed.owl FYPO:0008168 biolink:NamedThing abolished nuclear foci A cell phenotype observed in the vegetative growth phase of the life cycle in which the nuclear foci are absent. FYPO_relaxed.owl FYPO:0000006 biolink:NamedThing abnormal mitotic DNA damage checkpoint A cell cycle checkpoint phenotype in which any mitotic DNA damage checkpoint is abnormal. A mitotic DNA damage checkpoint normally regulates progression through the mitotic cell cycle in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0000157 biolink:NamedThing abnormal response to DNA damage stimulus during vegetative growth A stress response phenotype observed in the vegetative growth phase of the life cycle in which the response to DNA damage is abnormal. FYPO_relaxed.owl FYPO:0000188 biolink:NamedThing abnormal DNA repair during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which DNA repair is abnormal. FYPO_relaxed.owl FYPO:0000643 biolink:NamedThing abnormal mitotic DNA integrity checkpoint A cell cycle checkpoint phenotype in which a mitotic DNA integrity checkpoint is abnormal. A DNA integrity checkpoint normally regulates cell cycle progression in response to changes in DNA structure. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0000173 biolink:NamedThing abnormal mitotic cell cycle DNA replication checkpoint A cell cycle checkpoint phenotype in which the DNA replication checkpoint in a mitotic cell cycle is abnormal. The DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0000007 biolink:NamedThing abnormal S-phase DNA damage checkpoint A mitotic cell cycle checkpoint phenotype in which the S phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is abnormal. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0001707 biolink:NamedThing increased mitotic DNA damage checkpoint activation A cell cycle checkpoint phenotype in which the incidence of mitotic cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0002341 biolink:NamedThing increased duration of mitotic DNA damage checkpoint A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type. FYPO_relaxed.owl FYPO:0002900 biolink:NamedThing abnormal mitotic DNA damage checkpoint during cellular response to UV A cell cycle checkpoint phenotype in which any mitotic DNA damage checkpoint is abnormal when the cell is exposed to ultraviolet light. A DNA damage checkpoint normally regulates progression through the cell cycle in response to DNA damage. FYPO_relaxed.owl FYPO:0004371 biolink:NamedThing decreased duration of S-phase DNA damage checkpoint A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by the S-phase DNA damage checkpoint is lower than in wild type. FYPO_relaxed.owl FYPO:0004373 biolink:NamedThing abnormal mitotic G2 DNA damage checkpoint A cell cycle checkpoint phenotype in which the mitotic G2 DNA damage checkpoint is abnormal. The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0005603 biolink:NamedThing increased duration of mitotic DNA damage checkpoint during cellular response to methyl methanesulfonate A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type during a cellular response to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0000008 biolink:NamedThing abnormal meiotic recombination A cellular process phenotype in which reciprocal meiotic recombination is abnormal. Meiotic recombination is a cellular process in which double strand breaks are formed and repaired through a double Holliday junction intermediate, resulting in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. FYPO_relaxed.owl FYPO:0000063 biolink:NamedThing abnormal DNA recombination A cellular process phenotype in which DNA recombination is abnormal. DNA recombination is a process that results in reassortment of genes, producing gene combinations different from those that were present in the parents. FYPO_relaxed.owl FYPO:0001345 biolink:NamedThing abnormal DNA recombination during vegetative growth A cellular process phenotype in which DNA recombination is abnormal in the vegetative growth phase of the life cycle. DNA recombination is a process that results in reassortment of genes, producing gene combinations different from those that were present in the parents. FYPO_relaxed.owl FYPO:0002712 biolink:NamedThing decreased DNA recombination A cellular process phenotype in which the occurrence of DNA recombination is decreased. FYPO_relaxed.owl FYPO:0005399 biolink:NamedThing abolished double-strand break repair via homologous recombination A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair via homologous recombination does not occur. FYPO_relaxed.owl FYPO:0005406 biolink:NamedThing increased DNA recombination at telomere following meiotic cell cycle A cellular process phenotype in which the occurrence of DNA recombination is increased in telomeric regions in haploid cells that have undergone meiosis, sporulation and spore germination. FYPO_relaxed.owl FYPO:0005407 biolink:NamedThing increased DNA recombination at telomere during nitrogen starvation A cellular process phenotype in which the occurrence of DNA recombination is increased in telomeric regions when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006417 biolink:NamedThing increased duration of resolution of meiotic recombination intermediates A cellular process phenotype in which the duration of the cleavage and rejoining of intermediates formed during meiotic recombination is longer than normal. All intermediates or a subset (such as a specific type or configuration of intermediate) may remain present for longer than normal. FYPO_relaxed.owl FYPO:0006686 biolink:NamedThing decreased DNA double-strand break processing A cellular process phenotype in which DNA double-strand break resection is decreased. DNA double-strand break resection is the process by which long-tract single-stranded 3'-end DNA is generated by removal of bases from a 5' end from which SPO11/Rec12-oligonucleotide complexes have been removed. FYPO_relaxed.owl FYPO:0000860 biolink:NamedThing abnormal metabolic process A cellular process phenotype in which a cellular metabolic process is abnormal. A metabolic process is any set of chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. FYPO_relaxed.owl FYPO:0000181 biolink:NamedThing abolished crossover A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which reciprocal DNA recombination does not occur. FYPO_relaxed.owl FYPO:0000217 biolink:NamedThing abnormal DNA replication A cellular process phenotype in which DNA replication is abnormal. FYPO_relaxed.owl FYPO:0000526 biolink:NamedThing decreased peroxisome degradation A cellular process phenotype in which the occurrence of pexophagy is decreased. FYPO_relaxed.owl FYPO:0000527 biolink:NamedThing decreased rate of peroxisome degradation A cellular process phenotype in which the rate, or speed, of pexophagy is decreased. FYPO_relaxed.owl FYPO:0000528 biolink:NamedThing delayed onset of peroxisome degradation A cellular process phenotype in which pexophagy begins later than normal. FYPO_relaxed.owl FYPO:0001305 biolink:NamedThing abnormal long-chain fatty acid-CoA ligase activity A molecular function phenotype in which the observed rate of any long-chain fatty acid-CoA ligase activity is abnormal. FYPO_relaxed.owl FYPO:0001363 biolink:NamedThing abnormal metabolic process during vegetative growth A cellular process phenotype in which a cellular metabolic process is abnormal in the vegetative growth phase of the life cycle. A metabolic process is any set of chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. FYPO_relaxed.owl FYPO:0001935 biolink:NamedThing abnormal proton-transporting ATP synthase activity, rotational mechanism A molecular function phenotype in which the observed rate of proton-transporting ATP synthase activity by a rotational mechanism is abnormal. FYPO_relaxed.owl FYPO:0001937 biolink:NamedThing abnormal cytochrome-c oxidase activity A molecular function phenotype in which the observed rate of cytochrome-c oxidase activity is abnormal. FYPO_relaxed.owl FYPO:0001939 biolink:NamedThing abnormal ubiquinol-cytochrome-c reductase activity A molecular function phenotype in which the observed rate of ubiquinol-cytochrome-c reductase activity is abnormal. FYPO_relaxed.owl FYPO:0002036 biolink:NamedThing abnormal endodeoxyribonuclease activity A molecular function phenotype in which the observed rate of an endodeoxyribonuclease activity is abnormal. FYPO_relaxed.owl FYPO:0002274 biolink:NamedThing abnormal protein metabolic process A cellular process phenotype in which a protein metabolic process is abnormal. A protein metabolic process is a series of chemical reactions and pathways involving a specific protein. FYPO_relaxed.owl FYPO:0002491 biolink:NamedThing abnormal DNA 5'-adenosine monophosphate hydrolase activity A molecular function phenotype in which the observed rate of DNA 5'-adenosine monophosphate hydrolase activity is abnormal. FYPO_relaxed.owl FYPO:0002754 biolink:NamedThing abnormal cysteine synthase activity A molecular function phenotype in which the observed rate of cysteine synthase activity is abnormal. FYPO_relaxed.owl FYPO:0002856 biolink:NamedThing abnormal glutathione synthase activity A molecular function phenotype in which the observed rate of glutathione synthase activity is abnormal. FYPO_relaxed.owl FYPO:0003070 biolink:NamedThing abnormal single-stranded DNA 5'-3' exodeoxyribonuclease activity A molecular function phenotype in which the observed rate of a single-stranded DNA 5'-3' exodeoxyribonuclease activity is abnormal. FYPO_relaxed.owl FYPO:0003229 biolink:NamedThing abnormal hydrogen peroxide catabolism A cellular process phenotype in which the chemical breakdown of hydrogen peroxide is abnormal. FYPO_relaxed.owl FYPO:0003281 biolink:NamedThing abnormal superoxide dismutase activity A molecular function phenotype in which the observed rate of superoxide dismutase activity is abnormal. FYPO_relaxed.owl FYPO:0003320 biolink:NamedThing abnormal NADH dehydrogenase (ubiquinone) activity A molecular function phenotype in which the observed rate of NADH dehydrogenase (ubiquinone) activity is abnormal. FYPO_relaxed.owl FYPO:0003403 biolink:NamedThing abnormal glyoxalase III activity A molecular function phenotype in which the observed rate of glyoxalase III activity is abnormal. FYPO_relaxed.owl FYPO:0003433 biolink:NamedThing abnormal ornithine carbamoyltransferase activity A molecular function phenotype in which the observed rate of ornithine carbamoyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0003485 biolink:NamedThing abolished DNA synthesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the biosynthesis of DNA does not occur. FYPO_relaxed.owl FYPO:0003640 biolink:NamedThing abnormal adenylate kinase activity A molecular function phenotype in which the observed rate of adenylate kinase activity is abnormal. FYPO_relaxed.owl FYPO:0004519 biolink:NamedThing abnormal DNA-directed DNA polymerase activity A molecular function phenotype in which the observed rate or other catalytic property of a DNA-directed DNA polymerase activity is abnormal. FYPO_relaxed.owl FYPO:0004851 biolink:NamedThing abnormal RNA metabolic process A cellular process phenotype in which a protein metabolic process is abnormal. An RNA metabolic process is a series of chemical reactions and pathways involving any type of RNA. FYPO_relaxed.owl FYPO:0005539 biolink:NamedThing abnormal telomerase RNA reverse transcriptase activity A molecular function phenotype in which the observed rate of telomerase RNA reverse transcriptase activity is abnormal. FYPO_relaxed.owl FYPO:0005542 biolink:NamedThing abnormal telomerase template activity A molecular function phenotype in which telomerase template activity is abnormal. FYPO_relaxed.owl FYPO:0006551 biolink:NamedThing abnormal gene expression A cellular process phenotype in which gene expression is abnormal. One or more parts of gene expression, such as transcription or translation, may be affected, and all genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0006567 biolink:NamedThing abnormal DNA repair A cellular process phenotype in which DNA repair is abnormal. FYPO_relaxed.owl FYPO:0007296 biolink:NamedThing abolished UDP-galactose biosynthetic process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the biosynthesis of UDP-galactose does not occur. FYPO_relaxed.owl FYPO:0007363 biolink:NamedThing abnormal pyruvate kinase activity A molecular function phenotype in which the observed rate of pyruvate kinase activity is abnormal. FYPO_relaxed.owl FYPO:0007415 biolink:NamedThing abnormal telomere maintenance A cellular process phenotype in which telomere maintenance, i.e. any process that contributes to the maintenance of proper telomeric length and structure, is abnormal. FYPO_relaxed.owl FYPO:0007904 biolink:NamedThing abnormal glucan synthesis A cellular process phenotype in which glucan biosynthesis is abnormal. FYPO_relaxed.owl FYPO:0008082 biolink:NamedThing abnormal autophagy A cellular process phenotype in which autophagy is abnormal. Autophagy is the pathway by which cells digest parts of their own cytoplasm. FYPO_relaxed.owl FYPO:0003603 biolink:NamedThing abnormal meiosis I A cellular process phenotype in which the first meiotic nuclear division is abnormal. FYPO_relaxed.owl FYPO:0000197 biolink:NamedThing abnormal horsetail movement A cellular process phenotype in which horsetail movement is abnormal. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I. FYPO_relaxed.owl FYPO:0003378 biolink:NamedThing abolished meiosis I A cellular process phenotype in which the first meiotic nuclear division, in which homologous chromosomes are normally paired and segregated from each other, does not occur. FYPO_relaxed.owl FYPO:0004159 biolink:NamedThing abnormal homologous chromosome segregation A cellular process phenotype in which homologous chromosome segregation is abnormal. Homologous chromosome segregation is the process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. FYPO_relaxed.owl FYPO:0005599 biolink:NamedThing increased duration of meiosis I A cellular process phenotype in which the duration of the first meiotic nuclear division is longer than normal. FYPO_relaxed.owl FYPO:0006770 biolink:NamedThing abnormal kinetochore disassembly during meiotic prophase I A cellular process phenotype in which kinetochore disassembly is abnormal during prophase of meiosis I. Normally, outer kinetochore components delocalize from the centromere during bouquet formation in meiotic prophase I. FYPO_relaxed.owl FYPO:0007080 biolink:NamedThing abnormal initial meiotic spindle pole body separation in meiosis I A cellular process phenotype in which the initial release of duplicated spindle pole bodies that begins with the nucleation of microtubules from each SPB within the nucleus, and occurs as part of the first meiotic nuclear division, is abnormal. FYPO_relaxed.owl FYPO:0007083 biolink:NamedThing meiotic spindle collapse A cell phenotype in which a short meiotic spindle assembles, and may begin elongation, but does not elongate normally or completely, and eventually collapses. Upon collapse the spindle may break or shrink. FYPO_relaxed.owl FYPO:0007752 biolink:NamedThing spindle regression during meiosis I A cell phenotype in which a short spindle assembles during the first meiotic nuclear division, and may begin elongation, but then become shorter instead of continuing or resuming elongation. FYPO_relaxed.owl FYPO:0000009 biolink:NamedThing abnormal cell adhesion during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which adhesion of a cell to a substrate or another cell is abnormal. FYPO_relaxed.owl FYPO:0001362 biolink:NamedThing abnormal cellular process during vegetative growth A phenotype in which a specific cellular process is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000026 biolink:NamedThing abnormal vegetative cell polarity A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment or maintenance of cell polarity is abnormal. FYPO_relaxed.owl FYPO:0000147 biolink:NamedThing abnormal NETO A regulation phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) is abnormal. FYPO_relaxed.owl FYPO:0000186 biolink:NamedThing abnormal cell division A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell division is abnormal. FYPO_relaxed.owl FYPO:0000207 biolink:NamedThing abnormal cellular response to caffeine A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to caffeine is abnormal. FYPO_relaxed.owl FYPO:0000208 biolink:NamedThing abnormal cellular response to cadmium ion A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to cadmium ions is abnormal. FYPO_relaxed.owl FYPO:0000213 biolink:NamedThing abnormal vesicle-mediated transport during vegetative growth A transport phenotype observed in the vegetative growth phase of the life cycle in which vesicle-mediated transport is abnormal. FYPO_relaxed.owl FYPO:0000360 biolink:NamedThing abnormal RNA localization during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA localization is abnormal. FYPO_relaxed.owl FYPO:0000394 biolink:NamedThing abnormal mitotic G1/S phase transition A cellular process phenotype in which the G1/S transition of the mitotic cell cycle is abnormal. FYPO_relaxed.owl FYPO:0000399 biolink:NamedThing abnormal mitotic G2/M phase transition A cellular process phenotype in which the G2/M transition of the mitotic cell cycle is abnormal. FYPO_relaxed.owl FYPO:0000518 biolink:NamedThing abnormal nuclear transport during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear transport is abnormal. FYPO_relaxed.owl FYPO:0000522 biolink:NamedThing abnormal peroxisomal transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisomal transport is abnormal. FYPO_relaxed.owl FYPO:0000534 biolink:NamedThing abnormal mitotic spindle pole body localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body localization is abnormal. Spindle pole body localization is the process in which a whole spindle pole body is transported to, or maintained in, a specific location. FYPO_relaxed.owl FYPO:0000540 biolink:NamedThing abnormal protein transport during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport is abnormal. FYPO_relaxed.owl FYPO:0000591 biolink:NamedThing abnormal transposition A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transposition is abnormal. FYPO_relaxed.owl FYPO:0000597 biolink:NamedThing abnormal vacuolar transport during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuolar transport is abnormal. FYPO_relaxed.owl FYPO:0000721 biolink:NamedThing abnormal cellular response to pH A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to a pH stimulus is abnormal. FYPO_relaxed.owl FYPO:0000741 biolink:NamedThing increased cellular pigment accumulation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular pigment accumulation is increased. FYPO_relaxed.owl FYPO:0000931 biolink:NamedThing abnormal protein localization to microtubule cytoskeleton during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0001073 biolink:NamedThing abnormal myo-inositol import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of myo-inositol into the cell is abnormal. FYPO_relaxed.owl FYPO:0001129 biolink:NamedThing abnormal protein localization to nucleus during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abnormal. FYPO_relaxed.owl FYPO:0001341 biolink:NamedThing abnormal cellular response to stress during vegetative growth A cellular response phenotype in which a cellular response to stress is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001353 biolink:NamedThing abnormal cellular component organization during vegetative growth A cellular process phenotype in which any process of cellular component organization at the cellular level is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001361 biolink:NamedThing abnormal amino acid import during vegetative growth A cellular process phenotype in which the import of one or more amino acids into the cell is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001401 biolink:NamedThing abnormal protein localization to cell division site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is abnormal. FYPO_relaxed.owl FYPO:0001484 biolink:NamedThing abnormal cellular response to nutrient A chemical response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to a nutrient is abnormal. FYPO_relaxed.owl FYPO:0001584 biolink:NamedThing abnormal protein localization to cell tip during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is abnormal. FYPO_relaxed.owl FYPO:0001713 biolink:NamedThing abnormal malate import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of malate into the cell is abnormal. FYPO_relaxed.owl FYPO:0001715 biolink:NamedThing abnormal succinate import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of succinate into the cell is abnormal. FYPO_relaxed.owl FYPO:0001717 biolink:NamedThing abnormal malonic acid import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of malonic acid into the cell is abnormal. FYPO_relaxed.owl FYPO:0001721 biolink:NamedThing abnormal sodium export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of sodium ions out of a cell is abnormal. FYPO_relaxed.owl FYPO:0001737 biolink:NamedThing abnormal pantothenate import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of pantothenate into the cell is abnormal. FYPO_relaxed.owl FYPO:0001744 biolink:NamedThing abnormal biotin import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of biotin into the cell is abnormal. FYPO_relaxed.owl FYPO:0001747 biolink:NamedThing abnormal nickel import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of nickel ions into a cell is abnormal. FYPO_relaxed.owl FYPO:0001807 biolink:NamedThing abnormal adenine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of adenine into the cell is abnormal. FYPO_relaxed.owl FYPO:0001809 biolink:NamedThing abnormal guanine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of guanine into the cell is abnormal. FYPO_relaxed.owl FYPO:0001827 biolink:NamedThing abnormal glucose import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glucose into the cell is abnormal. FYPO_relaxed.owl FYPO:0001849 biolink:NamedThing abnormal ferric iron import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of ferric iron ions into a cell is abnormal. FYPO_relaxed.owl FYPO:0001930 biolink:NamedThing abnormal cellular response to gamma radiation A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to gamma radiation is abnormal. FYPO_relaxed.owl FYPO:0001932 biolink:NamedThing abnormal cellular response to hydroxyurea A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to hydroxyurea is abnormal. FYPO_relaxed.owl FYPO:0001951 biolink:NamedThing abnormal calcium export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of calcium ions out of a cell is abnormal. FYPO_relaxed.owl FYPO:0001953 biolink:NamedThing abnormal calcium import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of calcium ions into a cell is abnormal. FYPO_relaxed.owl FYPO:0002750 biolink:NamedThing abnormal sulfate import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of sulfate ions into the cell is abnormal. FYPO_relaxed.owl FYPO:0002814 biolink:NamedThing abnormal protein localization to cell surface A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is abnormal. The cell surface refers to the external part of the cell wall and/or plasma membrane. FYPO_relaxed.owl FYPO:0002838 biolink:NamedThing abnormal protein localization to chromosome during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a specific location on a chromosome is abnormal. FYPO_relaxed.owl FYPO:0003079 biolink:NamedThing abnormal genetic imprinting at mating-type locus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which genetic imprinting at the mating-type locus is abnormal. FYPO_relaxed.owl FYPO:0003154 biolink:NamedThing abnormal vegetative cell growth A cellular process phenotype in which cell growth is abnormal in the vegetative growth phase of the life cycle. Cell growth is the irreversible increase in size over time by accretion and biosynthetic production of matter similar to that already present. FYPO_relaxed.owl FYPO:0003283 biolink:NamedThing abnormal copper import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of copper ions into a cell is abnormal. FYPO_relaxed.owl FYPO:0003292 biolink:NamedThing abnormal UDP-galactose transmembrane transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UDP-galactose transmembrane transport is abnormal. FYPO_relaxed.owl FYPO:0003365 biolink:NamedThing abnormal pyridoxine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of pyridoxine into the cell is abnormal. FYPO_relaxed.owl FYPO:0003479 biolink:NamedThing constitutively activated MAPK cascade involved in cell wall organization or biogenesis A signal transduction phenotype in which the MAPK cascade involved in cell wall organization or biogenesis is activated continuously. FYPO_relaxed.owl FYPO:0003777 biolink:NamedThing abnormal protein localization to endoplasmic reticulum during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is abnormal. FYPO_relaxed.owl FYPO:0003936 biolink:NamedThing abnormal protein localization to Golgi apparatus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is abnormal. FYPO_relaxed.owl FYPO:0004179 biolink:NamedThing decreased protein aggregate fusion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which small aggregates of misfolded protein fuse into larger aggregates to a lower extent than normal. FYPO_relaxed.owl FYPO:0004336 biolink:NamedThing abnormal protein localization to mitochondrion A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion is abnormal. FYPO_relaxed.owl FYPO:0005017 biolink:NamedThing abnormal ribosome biogenesis A cell phenotype observed in the vegetative growth phase of the life cycle in which ribosome biogenesis is abnormal. FYPO_relaxed.owl FYPO:0005043 biolink:NamedThing abnormal regulation of translation in response to UV A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to ultraviolet light is abnormal. FYPO_relaxed.owl FYPO:0005161 biolink:NamedThing delayed onset of cell cycle progression following cellular response to hydroxyurea A cellular process phenotype in which cell cycle progression resumes after a longer time than normal after exposure to hydroxyurea. FYPO_relaxed.owl FYPO:0005165 biolink:NamedThing abnormal spatio-temporal regulation of replication fork localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the spatio-temporal pattern of localization of replication forks into nuclear foci is abnormal. Normally, replication forks appear organized into foci outside the nucleolus in early S phase. As S phase progresses, the number of foci first increases, then decreases, and the remaining foci concentrate within the nucleolus or at the nucleolar periphery. The last replication foci remaining at the end of S phase are one or two large spots at the nucleolar border. FYPO_relaxed.owl FYPO:0005170 biolink:NamedThing abnormal uracil import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of uracil into the cell is abnormal. FYPO_relaxed.owl FYPO:0005461 biolink:NamedThing abnormal microtubule-based movement during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule-based movement is abnormal. FYPO_relaxed.owl FYPO:0005490 biolink:NamedThing abnormal protein localization to vacuole A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuole is abnormal. FYPO_relaxed.owl FYPO:0005557 biolink:NamedThing decreased mitotic cohesin unloading A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin unloading is decreased during the mitotic cell cycle. Cohesin unloading is the topological unlinking of a cohesin ring complex from chromatin, which negatively regulates sister chromatid cohesion. FYPO_relaxed.owl FYPO:0005570 biolink:NamedThing abnormal protein localization to cell periphery during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell periphery is abnormal. FYPO_relaxed.owl FYPO:0005800 biolink:NamedThing abnormal protein movement within plasma membrane during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of one or more proteins within the plasma membrane is abnormal. FYPO_relaxed.owl FYPO:0005962 biolink:NamedThing abnormal sodium import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of sodium ions into a cell is abnormal. FYPO_relaxed.owl FYPO:0005964 biolink:NamedThing abnormal lithium import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of lithium ions into a cell is abnormal. FYPO_relaxed.owl FYPO:0005966 biolink:NamedThing abnormal potassium import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of potassium ions into a cell is abnormal. FYPO_relaxed.owl FYPO:0005982 biolink:NamedThing abnormal potassium export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of potassium ions out of a cell is abnormal. FYPO_relaxed.owl FYPO:0006223 biolink:NamedThing abnormal ferrous iron import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of ferrous iron ions into a cell is abnormal. FYPO_relaxed.owl FYPO:0006252 biolink:NamedThing abnormal tRNA folding A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the folding of tRNAs into the correct tertiary structure is abnormal. All tRNA folding may be abnormal, or the aminoacylation of one or more specific tRNAs may be affected. FYPO_relaxed.owl FYPO:0006267 biolink:NamedThing increased telomere clustering and tethering at nuclear periphery during mitotic metaphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere clustering and tethering at the nuclear periphery is increased during mitotic metaphase. FYPO_relaxed.owl FYPO:0006306 biolink:NamedThing abnormal actin filament-based process A cell phenotype observed in the vegetative growth phase of the life cycle in which an actin filament-based process, i.e. any process that depends upon or alters the actin cytoskeleton, is abnormal. FYPO_relaxed.owl FYPO:0006329 biolink:NamedThing abnormal organelle localization A cell phenotype observed in the vegetative growth phase of the life cycle in which organelle localization, i.e. any process in which an organelle is transported to, and/or maintained in, a specific location, is abnormal. FYPO_relaxed.owl FYPO:0006477 biolink:NamedThing abnormal mitotic metaphase/anaphase transition A cellular process phenotype in which the metaphase/anaphase transition of the mitotic cell cycle is abnormal. FYPO_relaxed.owl FYPO:0006901 biolink:NamedThing cell deflation and reinflation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a cell shrinks temporarily, but then recovers its original size. FYPO_relaxed.owl FYPO:0006922 biolink:NamedThing abnormal DNA clamp unloading A cell phenotype observed in the vegetative growth phase of the life cycle in which the removal of a sliding clamp such as PCNA from DNA during replication is abnormal. FYPO_relaxed.owl FYPO:0007395 biolink:NamedThing abnormal heme import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of heme into the cell is abnormal. FYPO_relaxed.owl FYPO:0007396 biolink:NamedThing decreased heme import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of heme into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007397 biolink:NamedThing abolished heme import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of heme into the cell is abolished. FYPO_relaxed.owl FYPO:0007440 biolink:NamedThing abnormal intracellular sterol transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the directed movement of sterols within cells is abnormal. FYPO_relaxed.owl FYPO:0007549 biolink:NamedThing coalescence of partially separated nuclei A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the two DNA masses separated by mitotic anaphase remain linked by the nuclear bridge, and then merge back into a single nucleus. FYPO_relaxed.owl FYPO:0007569 biolink:NamedThing abnormal septation initiation network signaling A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septation initiation network signaling is abnormal SIN signaling is mediated by the small GTPase Ras, and results in the initiation of contraction of the contractile ring at the beginning of cytokinesis and cell division by septum formation. FYPO_relaxed.owl FYPO:0007578 biolink:NamedThing abnormal protein localization to actin cytoskeleton during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actin cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0007587 biolink:NamedThing abnormal protein localization to endosome A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endosome(s) is abnormal. FYPO_relaxed.owl FYPO:0007672 biolink:NamedThing transcription scaling with nuclear size decoupled from cell size A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of transcription scales linearly with nuclear size instead of total cell size. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0007783 biolink:NamedThing abolished geometry scaling A cell phenotype in which cellular geometry scaling, by which cells normally maintain a fairly constant length:diameter (width) ratio upon changes in cell volume, does not occur. FYPO_relaxed.owl FYPO:0008132 biolink:NamedThing increased calcium signaling A cellular process phenotype observed in the vegetative growth phase of the life cycle in which calcium signaling is increased. FYPO_relaxed.owl FYPO:0001872 biolink:NamedThing abnormal cell adhesion A cellular process phenotype in which adhesion of a cell to a substrate or another cell is abnormal. FYPO_relaxed.owl FYPO:0001871 biolink:NamedThing increased agglutination A cell adhesion phenotype in which cells adhere to other cells of compatible mating type more strongly or to a greater extent than normal. FYPO_relaxed.owl FYPO:0003709 biolink:NamedThing decreased agglutination A cell adhesion phenotype in which cells adhere to other cells of compatible mating type less strongly or to a lower extent than normal. FYPO_relaxed.owl FYPO:0005504 biolink:NamedThing abolished galactose-specific flocculation A phenotype in which galactose-specific flocculation does not occur. Galactose-specific flocculation is the non-sexual aggregation of single cells, mediated by the binding of cell wall proteins on one cell to galactose residues on the other. FYPO_relaxed.owl FYPO:0000010 biolink:NamedThing abolished cell-substrate adhesion A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which cells fail to adhere to a substrate. FYPO_relaxed.owl FYPO:0001403 biolink:NamedThing increased cell-substrate adhesion A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which cells adhere to a substrate more strongly or to a greater extent than normal. FYPO_relaxed.owl FYPO:0005760 biolink:NamedThing increased cell-cell adhesion A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which cells adhere to each other more strongly or to a greater extent than normal. FYPO_relaxed.owl FYPO:0009112 biolink:NamedThing abolished flocculation during vegetative growth A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which flocculation does not occur in conditions where wild-type cells floculate. Flocculation is the non-sexual aggregation of cells. FYPO_relaxed.owl FYPO:0005449 biolink:NamedThing abolished cellular process A phenotype in which a specific cellular process does not occur. FYPO_relaxed.owl FYPO:0000371 biolink:NamedThing abolished RNA modification A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA modification does not occur. All RNA modification may be abolished, or one or more specific RNA modifications may be selectively affected. FYPO_relaxed.owl FYPO:0000375 biolink:NamedThing abolished apoptotic process A cellular process phenotype in which programmed cell death by apoptosis does not occur. Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. FYPO_relaxed.owl FYPO:0000380 biolink:NamedThing abolished macroautophagy A cellular process phenotype in which macroautophagy does not occur. FYPO_relaxed.owl FYPO:0000386 biolink:NamedThing abolished biofilm formation A cellular process phenotype in which biofilm formation does not occur. FYPO_relaxed.owl FYPO:0000413 biolink:NamedThing abolished cell fusion during mating A cellular process phenotype in which plasma membrane fusion involved in cytogamy does not occur. FYPO_relaxed.owl FYPO:0000417 biolink:NamedThing abolished cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic cytokinesis does not occur. FYPO_relaxed.owl FYPO:0000421 biolink:NamedThing abolished endocytosis during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis does not occur. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0000428 biolink:NamedThing abolished entry into G0 A cellular process phenotype in which the G1 to G0 transition does not occur. FYPO_relaxed.owl FYPO:0000431 biolink:NamedThing abolished fermentation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which fermentation does not occur. FYPO_relaxed.owl FYPO:0000474 biolink:NamedThing abolished meiosis A cellular process phenotype in which one or both meiotic nuclear division(s) does not occur. FYPO_relaxed.owl FYPO:0000484 biolink:NamedThing abolished meiotic recombination A cellular process phenotype in which reciprocal meiotic recombination does not occur. FYPO_relaxed.owl FYPO:0000491 biolink:NamedThing abolished mitochondrial genome maintenance A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial genome maintenance does not occur. FYPO_relaxed.owl FYPO:0000499 biolink:NamedThing abolished mitophagy A cellular process phenotype in which mitophagy does not occur. FYPO_relaxed.owl FYPO:0000507 biolink:NamedThing abolished nuclear export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear export does not occur. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected. FYPO_relaxed.owl FYPO:0000511 biolink:NamedThing abolished nuclear fusion during mating A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion does not occur. FYPO_relaxed.owl FYPO:0000514 biolink:NamedThing abolished nuclear import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear import does not occur. Nuclear import is the directed movement of any substance into the nucleus; import of all substances or a specific substance may be affected. FYPO_relaxed.owl FYPO:0000523 biolink:NamedThing abolished peroxisomal transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisomal transport does not occur. FYPO_relaxed.owl FYPO:0000525 biolink:NamedThing abolished peroxisome degradation A cellular process phenotype in which pexophagy does not occur. FYPO_relaxed.owl FYPO:0000537 biolink:NamedThing abolished protein secretion during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein secretion does not occur. FYPO_relaxed.owl FYPO:0000551 biolink:NamedThing pseudohyphal growth abolished A cellular process phenotype in which pseudohyphal growth does not occur. FYPO_relaxed.owl FYPO:0000556 biolink:NamedThing abolished re-entry into mitotic cell cycle after pheromone arrest A cellular process phenotype in which re-entry into the mitotic cell cycle after pheromone arrest does not occur. FYPO_relaxed.owl FYPO:0000562 biolink:NamedThing abolished cellular respiration A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular respiration does not occur. FYPO_relaxed.owl FYPO:0000569 biolink:NamedThing abolished shmoo formation A cellular process phenotype in which mating projection assembly does not occur. FYPO_relaxed.owl FYPO:0000583 biolink:NamedThing abolished sporulation A cellular process phenotype in which ascospore formation does not occur. FYPO_relaxed.owl FYPO:0000586 biolink:NamedThing abolished ascospore wall assembly A cellular process phenotype in which ascospore wall assembly does not occur. FYPO_relaxed.owl FYPO:0000592 biolink:NamedThing abolished transposition A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transposition does not occur. FYPO_relaxed.owl FYPO:0000907 biolink:NamedThing abolished mitochondrion inheritance during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion inheritance is abolished, resulting in the formation of a daughter cell that lacks mitochondria. FYPO_relaxed.owl FYPO:0000927 biolink:NamedThing abolished horsetail movement A cellular process phenotype in which horsetail movement does not occur. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I. FYPO_relaxed.owl FYPO:0001009 biolink:NamedThing abolished actomyosin contractile ring assembly A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of actin filaments and associated proteins does not occur, resulting in the failure to form an actomyosin contractile ring. FYPO_relaxed.owl FYPO:0001010 biolink:NamedThing abolished actin filament organization A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of cytoskeletal structures comprising actin filaments does not occur. FYPO_relaxed.owl FYPO:0001018 biolink:NamedThing abolished NETO A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) does not occur. FYPO_relaxed.owl FYPO:0001277 biolink:NamedThing abolished MCM complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which MCM complex assembly is abolished. FYPO_relaxed.owl FYPO:0001371 biolink:NamedThing abolished protein localization to medial cortex A cell phenotype in which the localization of a protein to the medial cortex is abolished. FYPO_relaxed.owl FYPO:0001585 biolink:NamedThing abolished protein localization to cell tip during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is abolished. FYPO_relaxed.owl FYPO:0001678 biolink:NamedThing abolished protein localization to chromatin A cell phenotype in which the localization of a protein to chromatin is abolished. FYPO_relaxed.owl FYPO:0001683 biolink:NamedThing abolished mitotic spindle assembly A cell phenotype in which mitotic spindle assembly does not occur. FYPO_relaxed.owl FYPO:0001734 biolink:NamedThing abolished mitotic spindle pole body separation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which duplicated mitotic spindle pole bodies do not separate. FYPO_relaxed.owl FYPO:0001746 biolink:NamedThing abolished biotin import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of biotin into the cell is abolished. FYPO_relaxed.owl FYPO:0001792 biolink:NamedThing abolished mitotic spindle pole body duplication A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle pole body duplication does not occur, leaving the cell with a single spindle pole body later in the cell cycle than normal. FYPO_relaxed.owl FYPO:0001826 biolink:NamedThing abolished sodium export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of sodium ions out of a cell does not occur. FYPO_relaxed.owl FYPO:0001828 biolink:NamedThing abolished glucose import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of guanine into the cell does not occur. FYPO_relaxed.owl FYPO:0001880 biolink:NamedThing abolished protein localization to cell division site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is abolished. FYPO_relaxed.owl FYPO:0001915 biolink:NamedThing abolished prospore membrane formation A cellular process phenotype in which prospore membrane formation does not occur. FYPO_relaxed.owl FYPO:0001946 biolink:NamedThing abolished mitotic sister chromatid separation A cellular process phenotype in which mitotic sister chromatid separation does not occur. FYPO_relaxed.owl FYPO:0002041 biolink:NamedThing abolished deadenylation-independent decapping of nuclear-transcribed mRNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which deadenylation-independent decapping of nuclear-transcribed mRNA does not occur. All RNA decapping may be abolished, or one or more specific RNA molecules may be selectively affected. FYPO_relaxed.owl FYPO:0002044 biolink:NamedThing abolished premeiotic DNA replication A cellular process phenotype in which premeiotic DNA replication does not occur. FYPO_relaxed.owl FYPO:0002348 biolink:NamedThing abolished stress granule assembly during vegetative growth A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly does not occur. FYPO_relaxed.owl FYPO:0002518 biolink:NamedThing abolished response to mitotic cell cycle checkpoint signaling A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to cell cycle checkpoint signaling does not occur. Abolished arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal. FYPO_relaxed.owl FYPO:0002678 biolink:NamedThing abolished protein phosphorylation A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur. FYPO_relaxed.owl FYPO:0002708 biolink:NamedThing abolished prospore formation A cellular process phenotype in which prospore formation does not occur. In prospore formation, each haploid nucleus becomes encapsulated by a double membrane. FYPO_relaxed.owl FYPO:0002759 biolink:NamedThing abolished protein localization to pre-autophagosomal structure A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the pre-autophagosomal structure is abolished. FYPO_relaxed.owl FYPO:0002815 biolink:NamedThing abolished protein localization to cell surface A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is abolished. The cell surface refers to the external part of the cell wall and/or plasma membrane. FYPO_relaxed.owl FYPO:0002841 biolink:NamedThing abolished protein localization to chromosome during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a specific location on a chromosome is abolished. FYPO_relaxed.owl FYPO:0002877 biolink:NamedThing abolished transcription A cellular process phenotype in which transcription does not occur. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0003084 biolink:NamedThing abolished replication fork arrest at mating-type locus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the mating-type locus does not occur. FYPO_relaxed.owl FYPO:0003181 biolink:NamedThing abolished meiotic DNA double-strand break formation A cellular process phenotype in which generation of double-strand breaks at defined hotspots throughout the genome during meiosis I does not occur. FYPO_relaxed.owl FYPO:0003182 biolink:NamedThing sister chromatid nondisjunction at meiosis II A cellular process phenotype in which sister chromatids are not segregated equally to the two spindle poles in the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0003253 biolink:NamedThing abolished amino acid import during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of one or more amino acids into the cell is abolished. FYPO_relaxed.owl FYPO:0003442 biolink:NamedThing abolished protein localization to actin cable A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more actin cables does not occur. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts. FYPO_relaxed.owl FYPO:0003450 biolink:NamedThing abolished protein localization to nucleus A cell phenotype in which the localization of a protein to the nucleus is abolished. FYPO_relaxed.owl FYPO:0003597 biolink:NamedThing abolished snRNA 3'-end processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of an snRNA molecule is abolished. FYPO_relaxed.owl FYPO:0003602 biolink:NamedThing abolished mRNA splicing, via spliceosome A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mRNA splicing via the spliceosome is abolished. FYPO_relaxed.owl FYPO:0003630 biolink:NamedThing abolished U2-type prespliceosome assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which U2-type prespliceosome assembly is abolished. The U2-type prespliceosome is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP, and also contains other proteins. FYPO_relaxed.owl FYPO:0003639 biolink:NamedThing abolished cell wall biogenesis A cellular process phenotype in which cell wall biogenesis is abolished. FYPO_relaxed.owl FYPO:0003655 biolink:NamedThing abolished tRNA splicing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the splicing tRNA substrates does not occur. FYPO_relaxed.owl FYPO:0003814 biolink:NamedThing abolished response to S-phase DNA damage checkpoint signaling A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the S phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) does not occur. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0003829 biolink:NamedThing abolished mitotic spindle elongation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle elongation does not occur. FYPO_relaxed.owl FYPO:0003838 biolink:NamedThing abolished actomyosin contractile ring contraction A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction does not occur. Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts. FYPO_relaxed.owl FYPO:0003844 biolink:NamedThing abolished mitotic chromosome condensation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation does not occur over all or part of the chromosomes. FYPO_relaxed.owl FYPO:0003887 biolink:NamedThing abolished endocytosis during meiotic cell cycle A cellular process phenotype in which endocytosis does not occur during a meiotic cell cycle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0003934 biolink:NamedThing abolished nuclear mRNA catabolic process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an RNA catabolic process that degrades mRNA encoded in the nucleus does not occur. Total mRNA or a specific mRNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0004060 biolink:NamedThing abolished endocytosis during meiotic interphase II A cellular process phenotype in which endocytosis does not occur during meiotic interphase II, i.e. the phase between the end of meiosis I cytokinesis the beginning of meiosis II prophase. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0004091 biolink:NamedThing abolished protein localization to microtubule cytoskeleton A cell phenotype in which the localization of a protein to the microtubule cytoskeleton is abolished. FYPO_relaxed.owl FYPO:0004259 biolink:NamedThing abolished mitotic G2 DNA damage checkpoint A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the mitotic G2 DNA damage checkpoint does not occur under conditions that normally trigger the checkpoint signaling and response. Normally, the mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage. FYPO_relaxed.owl FYPO:0004274 biolink:NamedThing abolished ascospore release from ascus A cellular process phenotype in which ascospore release from an ascus does not occur. FYPO_relaxed.owl FYPO:0004318 biolink:NamedThing abolished mitotic spindle assembly checkpoint A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the mitotic cell cycle spindle assembly checkpoint does not occur under conditions that normally trigger the checkpoint signaling and response. Normally, the mitotic spindle assembly checkpoint delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. FYPO_relaxed.owl FYPO:0004337 biolink:NamedThing abolished protein localization to mitochondrion A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion does not occur. FYPO_relaxed.owl FYPO:0004359 biolink:NamedThing abolished mitotic cell cycle DNA replication checkpoint A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the mitotic cell cycle DNA replication checkpoint does not occur under conditions that normally trigger the checkpoint signaling and response. The DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete. FYPO_relaxed.owl FYPO:0004484 biolink:NamedThing abolished protein localization to prospore membrane A cell phenotype in which the localization of a protein to the prospore membrane is abolished. FYPO_relaxed.owl FYPO:0004530 biolink:NamedThing abolished mitochondrial translation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial translation does not occur. FYPO_relaxed.owl FYPO:0004622 biolink:NamedThing abolished mitotic spindle disassembly A cell phenotype in which mitotic spindle disassembly does not occur. FYPO_relaxed.owl FYPO:0004623 biolink:NamedThing abolished astral microtubule anchoring at mitotic spindle pole body A cell phenotype in which astral microtubule anchoring at the mitotic spindle pole body does not occur. FYPO_relaxed.owl FYPO:0004624 biolink:NamedThing abolished eMTOC assembly A cell phenotype observed in the vegetative growth phase of the life cycle in which equatorial microtubule organizing center (eMTOC) assembly does not occur. eMTOC assembly is the aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center. FYPO_relaxed.owl FYPO:0004671 biolink:NamedThing abolished protein localization to vacuole during nitrogen starvation A cell phenotype in which the localization of a protein to the vacuole is abolished when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0004746 biolink:NamedThing abolished heterochromatin assembly involved in chromatin silencing at centromere outer repeat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly involved in chromatin silencing at the centromere outer repeat region does not occur. FYPO_relaxed.owl FYPO:0004763 biolink:NamedThing abolished protein localization to kinetochore during meiosis I A cell phenotype in which the localization of a protein to the kinetochore of a chromosome does not occur during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0004804 biolink:NamedThing abolished actin fusion focus assembly A cellular process phenotype in which actin fusion focus assembly does not occur. An actin fusion focus normally forms during mating at the site where the two cells will fuse. FYPO_relaxed.owl FYPO:0004839 biolink:NamedThing abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm, during glucose starvation A cell phenotype observed in which the localization of a protein to the plasma membrane is abolished when the cell is subject to glucose starvation, and the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0004889 biolink:NamedThing abolished protein localization to telomere during meiotic cell cycle A cell phenotype in which the localization of a protein to the telomere of a chromosome does not occur during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0004911 biolink:NamedThing abolished glutathione import into vacuole A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutathione into the vacuole does not occur. FYPO_relaxed.owl FYPO:0005140 biolink:NamedThing abolished meiotic recombination double-strand break repair A cellular process phenotype in which the repair of double-strand breaks formed as part of meiotic recombination does not occur. FYPO_relaxed.owl FYPO:0005174 biolink:NamedThing abolished uracil import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of uracil into the cell does not occur. FYPO_relaxed.owl FYPO:0005272 biolink:NamedThing abolished microtubule plus-end directed mitotic chromosome migration A cellular process phenotype in which microtubule plus-end directed mitotic chromosome migration does not occur. In microtubule plus-end directed mitotic chromosome migration, chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. FYPO_relaxed.owl FYPO:0005344 biolink:NamedThing abolished mitotic spindle midzone assembly A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which formation of the mitotic spindle midzone, the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap, does not occur. FYPO_relaxed.owl FYPO:0005356 biolink:NamedThing abolished site-specific DNA replication termination at RTS1 barrier A cellular process phenotype observed in the vegetative growth phase of the life cycle in which site-specific DNA replication termination at RTS1 barrier in the mating type region does not occur. FYPO_relaxed.owl FYPO:0005436 biolink:NamedThing abolished double-strand break repair A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair does not occur. FYPO_relaxed.owl FYPO:0005571 biolink:NamedThing abolished protein localization to cell periphery during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell periphery does not occur. FYPO_relaxed.owl FYPO:0005695 biolink:NamedThing abolished astral microtubule nucleation during mitosis A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of astral microtubules from the spindle pole body does not occur during mitosis. FYPO_relaxed.owl FYPO:0005696 biolink:NamedThing abolished cytoplasmic microtubule nucleation from iMTOC A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules from the interphase microtubule organizing center does not occur. Normally, microtubules are nucleated from interphase microtubule organizing centers (iMTOCs) and from the cytoplasmic face of the spindle pole body (SPB). FYPO_relaxed.owl FYPO:0005713 biolink:NamedThing abolished cytokinesis checkpoint A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the mitotic cytokinesis checkpoint does not occur under conditions that normally trigger the checkpoint signaling and response. Normally, the cytokinesis checkpoint normally delays the G2/M transition of a mitotic cell cycle if cytokinesis was not completed correctly in the previous cell cycle. FYPO_relaxed.owl FYPO:0005757 biolink:NamedThing abolished protein localization to membrane during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more membranes does not occur. FYPO_relaxed.owl FYPO:0005988 biolink:NamedThing abolished microtubule anchoring at cell cortex of cell tip during meiotic cell cycle A cell phenotype in which microtubule anchoring at the cell cortex of the cell tip does not occur during the meiotic cell cycle. Normally, anchoring maintains the localization of microtubules with their plus ends at the cell cortex. FYPO_relaxed.owl FYPO:0006001 biolink:NamedThing abolished protein localization to P-bodies A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to P-bodies does not occur. FYPO_relaxed.owl FYPO:0006067 biolink:NamedThing abolished microtubule polymerization A cell phenotype in which microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule, does not occur. FYPO_relaxed.owl FYPO:0006274 biolink:NamedThing abolished protein localization via NVT pathway A transport phenotype observed in the vegetative growth phase of the life cycle in which the localization of soluble cytosolic proteins to the vacuole lumen via the NVT pathway does not occur. FYPO_relaxed.owl FYPO:0006313 biolink:NamedThing abolished meiotic G2/MI transition A cell phenotype in which progression from meiotic G2 phase to M phase of meiosis I does not occur. FYPO_relaxed.owl FYPO:0006315 biolink:NamedThing abolished homologous chromosome segregation A cellular process phenotype in which homologous chromosome segregation does not occur. Homologous chromosome segregation is the process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. FYPO_relaxed.owl FYPO:0006343 biolink:NamedThing abolished microtubule bundle formation A cellular process phenotype in which microtubule bundle formation, which normally results in a parallel arrangement of microtubules, does not occur. FYPO_relaxed.owl FYPO:0006358 biolink:NamedThing abolished chromatin remodeling during glucose starvation A cellular process phenotype in which chromatin remodeling, i.e. any dynamic structural change to chromatin, does not occur when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0006366 biolink:NamedThing abolished meiotic telomere clustering A meiosis phenotype in which meiotic telomere clustering does not occur. Meiotic telomere clustering is the dynamic reorganization of telomeres in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. FYPO_relaxed.owl FYPO:0006424 biolink:NamedThing abolished meiotic sister chromatid cohesion at centromere during meiosis I A cellular process phenotype in which cohesion between sister chromatids does not occur in centromeric regions during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006427 biolink:NamedThing abolished attachment of spindle microtubules to kinetochore during meiosis I A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during the first meiotic nuclear division does not occur. FYPO_relaxed.owl FYPO:0006505 biolink:NamedThing abolished protein localization to shmoo tip A cell phenotype in which the localization of a protein to the tip of a shmoo, or mating projection, does not occur. FYPO_relaxed.owl FYPO:0006530 biolink:NamedThing abolished protein localization to centromere during meiotic prophase II A cell phenotype in which the localization of a protein to the centromere of a chromosome is abolished during prophase of the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0006534 biolink:NamedThing abolished protein localization to cell periphery during nitrogen starvation A cell phenotype in which the localization of a protein to the cell periphery does not occur when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006557 biolink:NamedThing abolished cell separation after cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis does not occur. FYPO_relaxed.owl FYPO:0006558 biolink:NamedThing abolished septum disassembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septum disassembly does not occur. FYPO_relaxed.owl FYPO:0006655 biolink:NamedThing abolished G-quadruplex DNA unwinding A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the unwinding of G-quadruplex DNA structures does not occur. FYPO_relaxed.owl FYPO:0006719 biolink:NamedThing abolished mitochondrial fission during cellular response to osmotic stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission does not occur during a cellular response to osmotic stress. Normally, mitochondria undergo fission when the cell is exposed to hyperosmotic conditions. FYPO_relaxed.owl FYPO:0006727 biolink:NamedThing abolished mitotic DNA replication elongation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which DNA strand elongation involved in mitotic nuclear DNA replication does not occur. FYPO_relaxed.owl FYPO:0006728 biolink:NamedThing abolished mitotic DNA replication initiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication does not occur at one or more origins. FYPO_relaxed.owl FYPO:0006763 biolink:NamedThing abolished meiotic cell cycle DNA replication checkpoint A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the meiotic cell cycle DNA replication checkpoint does not occur under conditions that normally trigger the checkpoint signaling and response. The meiotic DNA replication checkpoint normally prevents the initiation of meiotic nuclear division until pre-meiotic DNA replication is complete. FYPO_relaxed.owl FYPO:0007081 biolink:NamedThing abolished initial meiotic spindle pole body separation in meiosis I A cellular process phenotype in which the initial release of duplicated spindle pole bodies that begins with the nucleation of microtubules from each SPB within the nucleus, and normally occurs as part of the first meiotic nuclear division, does not occur. FYPO_relaxed.owl FYPO:0007165 biolink:NamedThing abolished protein localization to cell cortex during meiotic cell cycle A cell phenotype in which the localization of a protein to the cell cortex does not occur during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0007175 biolink:NamedThing abolished protein localization to plasma membrane at cell division site during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell division site is abolished during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007176 biolink:NamedThing abolished protein localization to plasma membrane at cell division site during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell division site is abolished during mitosis. FYPO_relaxed.owl FYPO:0007192 biolink:NamedThing abolished spindle pole body-led chromosome movement during mitotic interphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which rapid, back-and-forth movement of the mitotic spindle pole body (SPB), and associated chromosome movement, do not occur. Normally, SPB oscillation occurs during mitotic interphase (as well as prophase) but is restricted to a small space. FYPO_relaxed.owl FYPO:0007206 biolink:NamedThing abolished replication fork arrest at rDNA repeats A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at abnormal replication fork arrest at sites within the eukaryotic rDNA repeat spacer does not occur. FYPO_relaxed.owl FYPO:0007300 biolink:NamedThing abolished protein aggregate center formation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein aggregate center formation does not occur. Protein aggregate centers are composed of chaperones and misfolded proteins, and are reversibly formed in the nucleus and cytosol to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding. FYPO_relaxed.owl FYPO:0007343 biolink:NamedThing abolished lipid droplet formation A cellular process phenotype in which the occurrence of lipid droplet formation does not occur. FYPO_relaxed.owl FYPO:0007400 biolink:NamedThing abolished protein localization to kinetochore during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome does not occur during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007609 biolink:NamedThing abolished tRNA guanosine 7-methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 7-methylguanosine does not occur. FYPO_relaxed.owl FYPO:0007651 biolink:NamedThing abolished protein localization to pericentric heterochromatin during mitosis A cell phenotype in which the localization of a protein to pericentric heterochromatin is abolished during mitosis. FYPO_relaxed.owl FYPO:0007663 biolink:NamedThing abolished protein localization to kinetochore during meiosis II A cell phenotype in which the localization of a protein to the kinetochore of a chromosome does not occur during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0007851 biolink:NamedThing abolished spindle assembly during meiosis I A cell phenotype in which spindle assembly does not occur during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0000011 biolink:NamedThing abnormal cell cycle A cellular process phenotype in which a cell does not proceed normally through a cell cycle. FYPO_relaxed.owl FYPO:0000162 biolink:NamedThing abnormal cellular response to stress A cellular response phenotype in which a cellular response to stress is abnormal. FYPO_relaxed.owl FYPO:0000174 biolink:NamedThing abnormal cell wall biogenesis A cellular process phenotype in which cell wall biogenesis is abnormal. FYPO_relaxed.owl FYPO:0000302 biolink:NamedThing abnormal response to pheromone A conjugation phenotype in which a cell's response to mating pheromone is abnormal. FYPO_relaxed.owl FYPO:0000305 biolink:NamedThing abnormal spore germination A cellular process phenotype in which spore germination is abnormal. FYPO_relaxed.owl FYPO:0000335 biolink:NamedThing abnormal cellular component organization A cellular process phenotype in which any process of cellular component organization at the cellular level is abnormal. FYPO_relaxed.owl FYPO:0000517 biolink:NamedThing abnormal nucleus positioning A cellular process phenotype in which nucleus localization is abnormal. FYPO_relaxed.owl FYPO:0000629 biolink:NamedThing abnormal apoptotic process A cellular process phenotype in which programmed cell death by apoptosis is abnormal. Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. FYPO_relaxed.owl FYPO:0000630 biolink:NamedThing abnormal biofilm formation A cellular process phenotype in which biofilm formation is abnormal. FYPO_relaxed.owl FYPO:0001104 biolink:NamedThing abnormal catalase activity A molecular function phenotype in which the observed rate of catalase activity is abnormal. FYPO_relaxed.owl FYPO:0001106 biolink:NamedThing abnormal glutathione-disulfide reductase activity A molecular function phenotype in which the observed rate of glutathione-disulfide reductase activity is abnormal. FYPO_relaxed.owl FYPO:0001370 biolink:NamedThing abnormal protein localization A cell phenotype in which the localization of a protein in a cell is abnormal. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. FYPO_relaxed.owl FYPO:0001720 biolink:NamedThing abnormal transport A phenotype in which a specific transport process is abnormal. FYPO_relaxed.owl FYPO:0002517 biolink:NamedThing abnormal response to mitotic cell cycle checkpoint signaling A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to mitotic cell cycle checkpoint signaling is abnormal (does not occur, or occurs abnormally). Abnormal arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal. FYPO_relaxed.owl FYPO:0002862 biolink:NamedThing abnormal cell growth A cellular process phenotype in which cell growth is abnormal. Cell growth is the irreversible increase in size over time by accretion and biosynthetic production of matter similar to that already present. FYPO_relaxed.owl FYPO:0003025 biolink:NamedThing decreased homologous chromosome pairing A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased. Synapsis is the process in which the side by side pairing and physical juxtaposition of homologous chromosomes is established and maintained. Pairing may be assayed globally or at one or more specific loci. FYPO_relaxed.owl FYPO:0003026 biolink:NamedThing delayed onset of homologous chromosome pairing A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) begins later than normal. Synapsis is the process in which the side by side pairing and physical juxtaposition of homologous chromosomes is established and maintained. Pairing may be assayed globally or at one or more specific loci. FYPO_relaxed.owl FYPO:0003057 biolink:NamedThing abnormal RNA localization A cell phenotype in which the localization of an RNA in a cell is abnormal. An RNA may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. FYPO_relaxed.owl FYPO:0003363 biolink:NamedThing abolished cytogamy A cellular process phenotype in which cytogamy does not occur. Cytogamy is the process that creates a single cell from two cells of complementary mating types. FYPO_relaxed.owl FYPO:0003943 biolink:NamedThing abnormal thioredoxin peroxidase activity A molecular function phenotype in which the observed rate of thioredoxin peroxidase activity is abnormal. FYPO_relaxed.owl FYPO:0004035 biolink:NamedThing abnormal thioredoxin-disulfide reductase activity A molecular function phenotype in which the observed rate of thioredoxin-disulfide reductase activity is abnormal. FYPO_relaxed.owl FYPO:0004048 biolink:NamedThing abnormal glutathione peroxidase activity A molecular function phenotype in which the observed rate of glutathione peroxidase activity is abnormal. FYPO_relaxed.owl FYPO:0005568 biolink:NamedThing abnormal cell polarity A cellular process phenotype in which the establishment or maintenance of cell polarity is abnormal. FYPO_relaxed.owl FYPO:0005791 biolink:NamedThing abnormal shmoo directionality A cellular process phenotype in which a shmoo forms with normal morphology, but in an abnormal location. FYPO_relaxed.owl FYPO:0006380 biolink:NamedThing normal protein localization to vacuole during nitrogen starvation A cell phenotype in which the localization of a protein to the vacuole is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006525 biolink:NamedThing premature sister kinetochore separation during stationary phase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which sister kinetochores of a replicated chromosome separate prematurely when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0007163 biolink:NamedThing abnormal microtubule-based movement A cellular process phenotype in which microtubule-based movement is abnormal. FYPO_relaxed.owl FYPO:0007260 biolink:NamedThing abnormal cellular process during meiotic cell cycle A phenotype in which a specific cellular process is abnormal in the meiotic cell cycle. FYPO_relaxed.owl FYPO:0007768 biolink:NamedThing abnormal heterochromatin tethering at nuclear periphery A cellular process phenotype in which heterochromatin tethering at the nuclear periphery is abnormal. Normally, heterochromatic parts of chromosomes, such as centromeres and telomeres, are maintained at the nuclear periphery by tethering to the nuclear envelope during all or part of the cell cycle. FYPO_relaxed.owl FYPO:0007823 biolink:NamedThing abnormal quorum sensing A biological process phenotype in which any aspect of quorum sensing is abnormal. FYPO_relaxed.owl FYPO:0000631 biolink:NamedThing cell cycle phenotype A cellular process phenotype that affects progression of the mitotic or meiotic cell cycle, or regulation of cell cycle progression. FYPO_relaxed.owl FYPO:0000137 biolink:NamedThing mitotic cell cycle checkpoint phenotype A cell phenotype that affects any mitotic cell cycle checkpoint. FYPO_relaxed.owl FYPO:0001024 biolink:NamedThing cell cycle arrest phenotype A cell cycle phenotype that affects or involves the normal or abnormal occurrence of cell cycle arrest. In cell cycle arrest, progression through the cell cycle is halted during one of the normal phases (G1, S, G2, or M). FYPO_relaxed.owl FYPO:0005511 biolink:NamedThing meiotic cell cycle checkpoint phenotype A cell phenotype that affects any meiotic cell cycle checkpoint. FYPO_relaxed.owl FYPO:0000012 biolink:NamedThing mitotic G2/M phase transition delay A cell cycle phenotype in which the G2/M transition of the mitotic cell cycle begins later than normal. The duration of G2 phase is thus longer than normal. FYPO_relaxed.owl FYPO:0000166 biolink:NamedThing abnormal regulation of G2/M transition of mitotic cell cycle A regulation phenotype in which negative regulation of the G2 to M transition of the mitotic cell cycle is abnormal. FYPO_relaxed.owl FYPO:0000402 biolink:NamedThing increased mitotic G2/M phase transition A cellular process phenotype in which the occurrence of progression through the G2/M transition of the mitotic cell cycle is increased. FYPO_relaxed.owl FYPO:0002516 biolink:NamedThing premature mitotic G2/M phase transition A cell cycle phenotype in which the G2/M transition of the mitotic cell cycle begins earlier than normal. The duration of G2 phase is thus shorter than normal. The mitotic G2/M transition is the point at which a cell commits to entering M phase, and begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. FYPO_relaxed.owl FYPO:0000409 biolink:NamedThing delayed cell cycle phase transition A cellular process phenotype in which one or more cell cycle phase transitions begins later than normal. FYPO_relaxed.owl FYPO:0000324 biolink:NamedThing mitotic metaphase/anaphase transition delay A cell cycle phenotype in which the onset of anaphase of the mitotic cell cycle begins later than normal. FYPO_relaxed.owl FYPO:0000333 biolink:NamedThing mitotic G1/S phase transition delay A cell cycle phenotype in which the G1/S transition of the mitotic cell cycle begins later than normal. The duration of G1 phase is thus longer than normal. FYPO_relaxed.owl FYPO:0005384 biolink:NamedThing meiosis I metaphase/anaphase transition delay A cell cycle phenotype in which the onset of anaphase of the first meiotic nuclear division begins later than normal. FYPO_relaxed.owl FYPO:0005510 biolink:NamedThing meiosis II metaphase/anaphase transition delay A cell cycle phenotype in which the onset of anaphase of the second meiotic nuclear division begins later than normal. FYPO_relaxed.owl FYPO:0000563 biolink:NamedThing abnormal mitotic G2 phase progression A cellular process phenotype in which progression through the G2 phase of the mitotic cell cycle is abnormal. FYPO_relaxed.owl FYPO:0001069 biolink:NamedThing increased duration of mitotic cell cycle phase A cellular process phenotype in which the duration of one or more mitotic cell cycle phases is longer than normal. FYPO_relaxed.owl FYPO:0000274 biolink:NamedThing increased duration of mitotic M phase A cell cycle phenotype in which the duration of M phase of the mitotic cell cycle is longer than normal. FYPO_relaxed.owl FYPO:0000614 biolink:NamedThing increased duration of mitotic S phase A cellular process phenotype in which the duration of progression through S phase of the mitotic cell cycle is longer than normal. FYPO_relaxed.owl FYPO:0000618 biolink:NamedThing increased duration of mitotic anaphase A cellular process phenotype in which the duration of progression through anaphase of mitosis is longer than normal. FYPO_relaxed.owl FYPO:0005304 biolink:NamedThing increased duration of mitotic interphase A cellular process phenotype in which the duration of progression through interphase of the mitotic cell cycle is longer than normal. FYPO_relaxed.owl FYPO:0005683 biolink:NamedThing increased duration of mitotic prophase A cellular process phenotype in which the duration of progression through prophase of mitosis is longer than normal. FYPO_relaxed.owl FYPO:0000013 biolink:NamedThing T-shaped vegetative cell with normal cell length A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which cell length is normal, and a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T. FYPO_relaxed.owl FYPO:0007379 biolink:NamedThing T-shaped vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T. FYPO_relaxed.owl FYPO:0002848 biolink:NamedThing T-shaped cell during recovery from stationary phase A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T, when the cell population has been in stationary phase and is then placed in conditions that allow recovery. FYPO_relaxed.owl FYPO:0007380 biolink:NamedThing elongated T-shaped vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is longer than normal, and a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T. FYPO_relaxed.owl FYPO:0000014 biolink:NamedThing tapered cell A cell morphology phenotype in which the cell tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell. FYPO_relaxed.owl FYPO:0001126 biolink:NamedThing abnormal cell shape A cell morphology phenotype in which a cell has an abnormal shape. FYPO_relaxed.owl FYPO:0000015 biolink:NamedThing branched vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a daughter cell begins to grow from the lateral portion of the long axis of the cell, and at an angle to the septum or cell division site of the mother cell, resulting in the formation of a single cell that has a branch. FYPO_relaxed.owl FYPO:0000020 biolink:NamedThing pear-shaped cell A cell morphology phenotype in which a cell is shaped in the form of a pear. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell. FYPO_relaxed.owl FYPO:0000224 biolink:NamedThing lemon-shaped cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell grows in the form of a lemon. A lemon shape is defined mathematically as having a quadric surface in three dimensions obtained by rotating less than half of a circular arc about an axis passing through the endpoints of the arc. FYPO_relaxed.owl FYPO:0000358 biolink:NamedThing shmoo absent A physical cellular phenotype in which cells do not form mating projections. FYPO_relaxed.owl FYPO:0001879 biolink:NamedThing thin cell A cell morphology phenotype in which a cell has a smaller diameter (thickness; width) than normal. FYPO_relaxed.owl FYPO:0001955 biolink:NamedThing spheroid cell A cell morphology phenotype in which a cell is shaped in the form of a spheroid. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged. FYPO_relaxed.owl FYPO:0002196 biolink:NamedThing abnormal vegetative cell shape A cell phenotype in which cell shape is altered in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0002427 biolink:NamedThing inviable spore with abnormal shape A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and has an abnormal shape. An inviable spore does not germinate. FYPO_relaxed.owl FYPO:0002467 biolink:NamedThing abnormal spore shape A cell phenotype in which a spore has an abnormal shape. FYPO_relaxed.owl FYPO:0004807 biolink:NamedThing narrow cell fusion site following mating A cell morphology phenotype in which the cell is narrower than normal at the point where cell fusion occurred during mating. Normally, the cell expands at the fusion site after fusion takes place. FYPO_relaxed.owl FYPO:0005566 biolink:NamedThing T-shaped cell A cell morphology phenotype in which a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T. Cell length is normal. FYPO_relaxed.owl FYPO:0005793 biolink:NamedThing bent cell A cell morphology phenotype in which a cell is bent along the long axis. In a bent cell, the long axis has one or more angles, rather than following a straight line. FYPO_relaxed.owl FYPO:0006615 biolink:NamedThing increased cell diameter A cell morphology phenotype in which a cell has a greater diameter (thickness; width) than normal. FYPO_relaxed.owl FYPO:0006633 biolink:NamedThing increased cell length A cell morphology phenotype in which cell length, i.e. the maximum distance between the cell ends, is greater than normal. FYPO_relaxed.owl FYPO:0007230 biolink:NamedThing spindle-shaped cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell grows in the form of a spindle, i.e. both cell tips are narrower and more pointed than normal. FYPO_relaxed.owl FYPO:0001118 biolink:NamedThing abnormal vegetative cell morphology A cell phenotype in which cell morphology (i.e. the size, shape, or structure of the cell) is altered in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000021 biolink:NamedThing spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged. FYPO_relaxed.owl FYPO:0000648 biolink:NamedThing viable small vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable but has an abnormally low volume. Note that small viable cells may result from a cell cycle size regulation defect. FYPO_relaxed.owl FYPO:0000951 biolink:NamedThing inviable small vegetative cell A cell morphology phenotype in which a vegetative cell is inviable and has an abnormally low volume. FYPO_relaxed.owl FYPO:0002273 biolink:NamedThing inviable vegetative cell with abnormal cell morphology A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has abnormal morphology (i.e. size, shape, or structure) and is inviable. FYPO_relaxed.owl FYPO:0002377 biolink:NamedThing viable swollen vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0002414 biolink:NamedThing inviable swollen vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0003595 biolink:NamedThing S-shaped cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell grows in a shape that consists of two curves in opposite directions. FYPO_relaxed.owl FYPO:0004257 biolink:NamedThing swollen multinucleate vegetative cell A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one nucleus and has a larger volume than normal. FYPO_relaxed.owl FYPO:0005475 biolink:NamedThing swollen vegetative cell with normal cell length A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is normal length but has a larger volume than normal. FYPO_relaxed.owl FYPO:0007136 biolink:NamedThing small mononucleate vegetative cell A cell phenotype in which a cell contains one nucleus and has an abnormally low volume. FYPO_relaxed.owl FYPO:0007137 biolink:NamedThing small multinucleate vegetative cell A cell morphology phenotype in which a vegetative cell has an abnormally low volume and contains more than one nucleus. FYPO_relaxed.owl FYPO:0000016 biolink:NamedThing curved vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0000024 biolink:NamedThing stubby vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which the cell diameter is larger than normal and the cell length is shorter than normal. FYPO_relaxed.owl FYPO:0000060 biolink:NamedThing mononucleate vegetative cell A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a single nucleus. FYPO_relaxed.owl FYPO:0000129 biolink:NamedThing spherical vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is formed in the shape of a sphere. FYPO_relaxed.owl FYPO:0000455 biolink:NamedThing increased number of double-strand break sites during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites of double-strand breaks in DNA is greater than normal. FYPO_relaxed.owl FYPO:0000645 biolink:NamedThing small vegetative cell A cell morphology phenotype in which a vegetative cell has an abnormally low volume. FYPO_relaxed.owl FYPO:0000646 biolink:NamedThing swollen vegetative cell A cell morphology phenotype in which a vegetatively growing cell has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0001313 biolink:NamedThing normal subcellular component during vegetative growth A cell phenotype in which the amount, distribution, or morphology of a cell part is normal (i.e. indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001315 biolink:NamedThing normal vegetative cell morphology A cell phenotype characterized by normal cell morphology (i.e. size, shape, and structure indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001316 biolink:NamedThing normal level of substance in cell during vegetative growth A cell phenotype in which the amount of a specific substance measured in a cell is normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001322 biolink:NamedThing abnormal subcellular component during vegetative growth A physical cellular phenotype in which the amount, distribution, morphology, or other physical characteristic of a cell part is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0002071 biolink:NamedThing mislocalized nucleus during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a nucleus in an abnormal location. The normal location of a single nucleus is at the midpoint of the long axis of the cell (during mitotic telophase, daughter nuclei normally move away from the cell division site). FYPO_relaxed.owl FYPO:0003988 biolink:NamedThing mislocalized actin cortical patches during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has actin cortical patches in one or more abnormal locations. FYPO_relaxed.owl FYPO:0004296 biolink:NamedThing septated cell A physical cellular phenotype in which the cell contains one or more septa. FYPO_relaxed.owl FYPO:0004700 biolink:NamedThing bent vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is bent along the long axis. In a bent cell, the long axis has one or more angles, rather than following a straight line. FYPO_relaxed.owl FYPO:0006634 biolink:NamedThing increased vegetative cell length A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which cell length, i.e. the maximum distance between the cell ends, is greater than normal. FYPO_relaxed.owl FYPO:0007328 biolink:NamedThing normal number of Rad52 foci during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008171 biolink:NamedThing increased nuclear pore complex clustering A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear pore complexes are more clustered together than normal. FYPO_relaxed.owl FYPO:0000945 biolink:NamedThing swollen spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0001119 biolink:NamedThing tapered vegetative cell A cell morphology phenotype in which the cell tapers at one end to a diameter smaller than the other in the vegetative growth phase of the life cycle. The cell diameter at the narrow end is smaller than that of a wild-type cell. FYPO_relaxed.owl FYPO:0001120 biolink:NamedThing pear-shaped vegetative cell A cell morphology phenotype in which a cell is shaped in the form of a pear in the vegetative growth phase of the life cycle. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell. FYPO_relaxed.owl FYPO:0001121 biolink:NamedThing vegetative cell, abnormal cell shape, normal cell size A cell phenotype in which cell shape is altered, but cell size remains normal, in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001122 biolink:NamedThing elongated vegetative cell A cell phenotype in which a cell is longer, and has a greater length:diameter ratio, than normal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0002084 biolink:NamedThing swollen stubby vegetative cell A cell morphology phenotype in which a vegetative cell has a larger volume and cell diameter, but shorter cell length, than normal. FYPO_relaxed.owl FYPO:0002197 biolink:NamedThing viable vegetative cell with abnormal cell shape A cell phenotype in which a cell is viable, and cell shape is altered in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0002421 biolink:NamedThing inviable after spore germination, single or double cell division, abnormal cell shape A phenotype in which a spore germinates to produce a cell that has an abnormal shape and undergoes one or two rounds of cell division. FYPO_relaxed.owl FYPO:0002451 biolink:NamedThing inviable vegetative cell with abnormal cell shape A cell phenotype in which a cell is inviable and cell shape is altered in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0005149 biolink:NamedThing septated spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid and has one or more septa. FYPO_relaxed.owl FYPO:0006616 biolink:NamedThing viable vegetative cell with increased cell diameter A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable and has a diameter greater than normal. Cell volume may or may not be increased. FYPO_relaxed.owl FYPO:0000017 biolink:NamedThing elongated cell A cell morphology phenotype in which cells are longer than normal, and the length:diameter ratio is greater than normal. FYPO_relaxed.owl FYPO:0001123 biolink:NamedThing elongated spore A cell phenotype in which a spore is longer than normal. FYPO_relaxed.owl FYPO:0001429 biolink:NamedThing swollen elongated cell A cell morphology phenotype in which a cell has a larger volume, greater length, greater diameter, and greater length:diameter ratio than normal. FYPO_relaxed.owl FYPO:0003342 biolink:NamedThing elongated multinucleate cell A cell phenotype in which a cell contains more than one nucleus, is longer than normal, and has a greater length:diameter ratio than normal. FYPO_relaxed.owl FYPO:0008096 biolink:NamedThing increased cell size A cell size phenotype in which a cell has a volume that is larger than normal. FYPO_relaxed.owl FYPO:0000025 biolink:NamedThing swollen cell A cell morphology phenotype in which a cell has a larger volume than normal. In a swollen cell, both length and diameter are greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0008095 biolink:NamedThing increased cell size during G0 A cell size phenotype in which a cell has a volume that is larger than normal during G0. FYPO_relaxed.owl FYPO:0008106 biolink:NamedThing increased cell size during stationary phase A cell size phenotype in which a cell has a volume that is larger than normal during stationary phase. FYPO_relaxed.owl FYPO:0001956 biolink:NamedThing spherical cell A cell morphology phenotype in which a cell is formed in the shape of a sphere. FYPO_relaxed.owl FYPO:0002193 biolink:NamedThing inviable normal volume septated spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, contains one or more septa, is shaped in the form of a spheroid, and has a normal volume. FYPO_relaxed.owl FYPO:0002941 biolink:NamedThing swollen spheroid cell A cell morphology phenotype in which a cell is shaped in the form of a spheroid, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged. FYPO_relaxed.owl FYPO:0006538 biolink:NamedThing spheroid cell during cellular response to pheromone A cell morphology phenotype in which a cell is shaped in the form of a spheroid during a cellular response to a pheromone. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged. FYPO_relaxed.owl FYPO:0000022 biolink:NamedThing shmoo with long tip A cell morphology phenotype in which a cell forms a mating projection with a longer tip than normal. FYPO_relaxed.owl FYPO:0000357 biolink:NamedThing abnormal shmoo morphology A physical cellular phenotype in which the size, shape, or structure of the mating projection is abnormal. FYPO_relaxed.owl FYPO:0007658 biolink:NamedThing shmoo with flat tip A cell morphology phenotype in which a cell forms a mating projection with a flatter (less rounded) tip than normal. FYPO_relaxed.owl FYPO:0000023 biolink:NamedThing small cell A cell morphology phenotype in which a cell has an abnormally low volume. FYPO_relaxed.owl FYPO:0001127 biolink:NamedThing abnormal cell size A cell morphology phenotype in which a cell has a volume or dimensions that differ from normal. FYPO_relaxed.owl FYPO:0007910 biolink:NamedThing increased vegetative cell shrinkage A cell size phenotype in which a vegetative cell has a reduced volume or dimensions compared to a size previously observed for the same cell. FYPO_relaxed.owl FYPO:0005569 biolink:NamedThing abnormal cell polarity during G0 to G1 transition A cellular process phenotype in which the establishment or maintenance of cell polarity is abnormal when the cell undergoes transition from G0 phase to G1. FYPO_relaxed.owl FYPO:0000027 biolink:NamedThing abnormal cell wall during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the cell wall is abnormal. FYPO_relaxed.owl FYPO:0000050 biolink:NamedThing abnormal kinetochore morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the kinetochore is abnormal. FYPO_relaxed.owl FYPO:0000055 biolink:NamedThing long microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form microtubules that are longer than normal. FYPO_relaxed.owl FYPO:0000057 biolink:NamedThing mitochondrial nucleoid enlarged A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitochondrial nucleoid is larger than normal. FYPO_relaxed.owl FYPO:0000058 biolink:NamedThing mitochondrial nucleoids present in decreased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer mitochondrial nucleoids than normal. FYPO_relaxed.owl FYPO:0000061 biolink:NamedThing multinucleate vegetative cell A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one nucleus. FYPO_relaxed.owl FYPO:0000062 biolink:NamedThing abnormal nuclear morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the nucleus is abnormal. FYPO_relaxed.owl FYPO:0000118 biolink:NamedThing multiseptate vegetative cell A physical cellular phenotype observed in the vegetative growth phase of the life cycle characterized by the presence of more than one septum in a cell. FYPO_relaxed.owl FYPO:0000338 biolink:NamedThing abnormal mitotic spindle A physical cellular phenotype in which the position or morphology of the mitotic spindle is abnormal. FYPO_relaxed.owl FYPO:0000356 biolink:NamedThing abnormal lipid droplet morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of lipid droplets is abnormal. FYPO_relaxed.owl FYPO:0000361 biolink:NamedThing abnormal nucleolar morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the nucleolus is abnormal. FYPO_relaxed.owl FYPO:0000362 biolink:NamedThing abnormal peroxisomal morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the peroxisome is abnormal. FYPO_relaxed.owl FYPO:0000363 biolink:NamedThing peroxisomes absent A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells do not contain peroxisomes. FYPO_relaxed.owl FYPO:0001008 biolink:NamedThing actomyosin contractile ring absent A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the actomyosin contractile ring is absent from the cell. FYPO_relaxed.owl FYPO:0001011 biolink:NamedThing filamentous actin absent A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells do not contain filamentous actin structures, such as cortical patches or dots, or rings. FYPO_relaxed.owl FYPO:0001474 biolink:NamedThing abnormal mitotic spindle pole body morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the mitotic spindle pole body is abnormal. FYPO_relaxed.owl FYPO:0001581 biolink:NamedThing vacuolated A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are more visible (usually by microscopy) than normal. A vacuolated phenotype may be due to the presence of more vacuoles in a cell than normal, or to vacuoles located nearer the cell surface (and hence more visible) than normal. FYPO_relaxed.owl FYPO:0001895 biolink:NamedThing P-bodies present in increased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more cytoplasmic mRNA processing bodies (P-bodies) than normal. FYPO_relaxed.owl FYPO:0001896 biolink:NamedThing enlarged P-bodies A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic mRNA processing bodies (P-bodies) are larger than normal. FYPO_relaxed.owl FYPO:0001897 biolink:NamedThing P-bodies present in decreased numbers during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer cytoplasmic mRNA processing bodies (P-bodies) than normal. FYPO_relaxed.owl FYPO:0001901 biolink:NamedThing small P-bodies during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic mRNA processing bodies (P-bodies) are smaller than normal. FYPO_relaxed.owl FYPO:0002250 biolink:NamedThing inviable curved vacuolated vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is curved along the long axis, and in which vacuoles are more visible (usually by microscopy) than normal. FYPO_relaxed.owl FYPO:0002254 biolink:NamedThing abnormal telomere morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the telomere is abnormal. FYPO_relaxed.owl FYPO:0002404 biolink:NamedThing abnormal endomembrane system A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the endomembrane system is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0002410 biolink:NamedThing inviable vacuolated vegetative cell, abnormal cell shape, normal cell size A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, cell shape is altered, and cell size remains normal, and in which vacuoles are more visible (usually by microscopy) than normal. FYPO_relaxed.owl FYPO:0002449 biolink:NamedThing signal recognition particles present in decreased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer signal recognition particles (SRPs) than normal. FYPO_relaxed.owl FYPO:0002455 biolink:NamedThing abnormal septum during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the position or morphology of all or part of the septum is abnormal. FYPO_relaxed.owl FYPO:0002476 biolink:NamedThing viable vacuolated vegetative cell, abnormal cell shape, normal cell size A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, cell shape is altered, and cell size remains normal, and in which vacuoles are more visible (usually by microscopy) than normal. FYPO_relaxed.owl FYPO:0002478 biolink:NamedThing viable curved vacuolated vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable and is curved along the long axis, and in which vacuoles are more visible (usually by microscopy) than normal. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0002552 biolink:NamedThing lipid droplets present in decreased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer lipid droplets than normal. FYPO_relaxed.owl FYPO:0002639 biolink:NamedThing increased interkinetochore distance before mitotic anaphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between sister kinetochores is greater than normal before the onset of mitotic anaphase. FYPO_relaxed.owl FYPO:0002654 biolink:NamedThing enlarged exocytic vesicles A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which exocytic vesicles are larger than normal. FYPO_relaxed.owl FYPO:0002760 biolink:NamedThing short cytoplasmic microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are shorter than normal. FYPO_relaxed.owl FYPO:0003278 biolink:NamedThing abnormal plasma membrane during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the position, morphology, or physical characteristics of all or part of the plasma membrane is abnormal. FYPO_relaxed.owl FYPO:0003328 biolink:NamedThing misoriented interphase microtubules A microtubule organization phenotype observed in the vegetative growth phase of the life cycle in which the orientation of cytoplasmic microtubules within a cell is abnormal during interphase of the mitotic cell cycle. The normal orientation is parallel to the long axis of the cell. FYPO_relaxed.owl FYPO:0003416 biolink:NamedThing cytoplasmic vesicles present in increased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more cytoplasmic membrane-bounded vesicles than normal. FYPO_relaxed.owl FYPO:0003448 biolink:NamedThing viable swollen vacuolated spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, is shaped in the form of a spheroid, has a larger volume than normal, and in which vacuoles are more visible (usually by microscopy) than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0003711 biolink:NamedThing lateral cortical nodes absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain any detectable Skb1-containing lateral cortical nodes. FYPO_relaxed.owl FYPO:0003712 biolink:NamedThing lateral cortical nodes present in increased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more Skb1-containing lateral cortical nodes than normal. FYPO_relaxed.owl FYPO:0003820 biolink:NamedThing mitochondria present in decreased numbers during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer mitochondria than normal. FYPO_relaxed.owl FYPO:0004747 biolink:NamedThing actin cortical patches present in increased numbers at cell tip during early mitosis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more actin cortical patches at one or both cell tips than normal during early mitosis (before anaphase). FYPO_relaxed.owl FYPO:0004790 biolink:NamedThing abnormal telomere-nuclear envelope distance during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between one or more telomeres and the nuclear envelope is abnormal (i.e. greater or less than the distance in wild type cells). FYPO_relaxed.owl FYPO:0004862 biolink:NamedThing curved microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form microtubules that are curved, i.e. follow a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0004863 biolink:NamedThing long curved microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form microtubules that are longer than normal and are curved, i.e. follow a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0004943 biolink:NamedThing abnormal mitochondrion A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, morphology, or other physical characteristic of the mitochondrion is abnormal. FYPO_relaxed.owl FYPO:0005425 biolink:NamedThing curved elongated vegetative cell with long curved interphase microtubules A cell morphology phenotype in which a vegetatively growing cell is elongated, is curved along the long axis, and contains cytoplasmic microtubules that are longer than normal and curved. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0005860 biolink:NamedThing Mei2 nuclear dot present in cell during vegetative growth A cell phenotype in which the cell contains a detectable Mei2 nuclear dot complex during the vegetative growth phase of the life cycle. Normally the Mei2 nuclear dot is only present during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0006018 biolink:NamedThing decreased nuclear pore density A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer nuclear pore complexes than normal. FYPO_relaxed.owl FYPO:0006027 biolink:NamedThing actin cables present in increased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more actin cables than normal. FYPO_relaxed.owl FYPO:0006047 biolink:NamedThing decreased interkinetochore distance before mitotic anaphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between sister kinetochores is smaller than normal before the onset of mitotic anaphase. FYPO_relaxed.owl FYPO:0006196 biolink:NamedThing short misoriented interphase microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are shorter than normal and have abnormal orientation. The normal orientation is parallel to the long axis of the cell. FYPO_relaxed.owl FYPO:0006215 biolink:NamedThing actin cables present in decreased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer actin cables than normal. FYPO_relaxed.owl FYPO:0006399 biolink:NamedThing abnormal septin ring morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of the septin ring is abnormal. FYPO_relaxed.owl FYPO:0006801 biolink:NamedThing spindle pole bodies present in increased numbers during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more spindle pole bodies (SPBs) than normal. In this phenotype, extra SPBs typically contain normal components but seldom attach to spindle microtubules. FYPO_relaxed.owl FYPO:0007194 biolink:NamedThing mitochondria present in increased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more mitochondria than normal. FYPO_relaxed.owl FYPO:0007195 biolink:NamedThing large mitochondria A cell phenotype observed in the vegetative growth phase of the life cycle in which mitochondria are larger than normal. FYPO_relaxed.owl FYPO:0007262 biolink:NamedThing abnormal eisosome A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, morphology, or other physical characteristic of the eisosome is abnormal. The eisosome consists of a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. FYPO_relaxed.owl FYPO:0007516 biolink:NamedThing decreased DNA volume A cell phenotype observed in the vegetative growth phase of the life cycle in which DNA occupies a smaller portion of the total nuclear volume than normal. The nuclear volume itself may be normal. FYPO_relaxed.owl FYPO:0007610 biolink:NamedThing decreased mitochondrial volume A cell phenotype observed in the vegetative growth phase of the life cycle in which the total volume of all mitochondria in the cell is lower than normal. FYPO_relaxed.owl FYPO:0007712 biolink:NamedThing mitochondria absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain any detectable mitochondria. FYPO_relaxed.owl FYPO:0007713 biolink:NamedThing large ERMES foci present in decreased numbers A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer, but larger, ERMES foci than normal. An ERMES focus is a site that contains one or more ERMES complex(es). FYPO_relaxed.owl FYPO:0000029 biolink:NamedThing abnormal chromosome segregation A cellular process phenotype in which chromosome segregation is abnormal. Chromosome segregation begins with the alignment of chromosomes at the metaphase plate, includes sister chromatid separation, and ends when chromosomes have completed movement to the spindle poles. FYPO_relaxed.owl FYPO:0002734 biolink:NamedThing abnormal cell cycle process A cellular process phenotype in which a cell does not execute a cell cycle process normally. A cell cycle process is any of the processes that form part of the cell cycle, and thereby ensures successive accurate and complete genome replication and chromosome segregation. FYPO_relaxed.owl FYPO:0000427 biolink:NamedThing abnormal G1 to G0 transition A cellular process phenotype in which the G1 to G0 transition is abnormal. FYPO_relaxed.owl FYPO:0000555 biolink:NamedThing abnormal re-entry into mitotic cell cycle after pheromone arrest A cellular process phenotype in which re-entry into the mitotic cell cycle after pheromone arrest is abnormal. FYPO_relaxed.owl FYPO:0000773 biolink:NamedThing abnormal pre-replicative complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which pre-replicative complex assembly is abnormal. FYPO_relaxed.owl FYPO:0002092 biolink:NamedThing abnormal meiotic sister chromatid cohesion A cellular process phenotype in which cohesion between sister chromatids is abnormal during meiosis. FYPO_relaxed.owl FYPO:0002737 biolink:NamedThing abnormal mitotic cell cycle process A cellular process phenotype in which a cell does not execute a mitotic cell cycle process normally. A mitotic cell cycle process is any of the processes that form part of the mitotic cell cycle, and thereby ensures successive accurate and complete genome replication and chromosome segregation during the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0002739 biolink:NamedThing abnormal meiotic cell cycle process A cellular process phenotype in which a cell does not execute a meiotic cell cycle process normally. A meiotic cell cycle process is any of the processes that form part of the meiotic cell cycle, and thereby ensures successive accurate and complete genome replication and meiotic chromosome segregation. FYPO_relaxed.owl FYPO:0002955 biolink:NamedThing abnormal G0 to G1 transition A cellular process phenotype in which the transition from G0 phase (quiescence) to G1 is abnormal. FYPO_relaxed.owl FYPO:0003560 biolink:NamedThing abnormal spindle pole body organization A cell phenotype in which spindle pole body organization is abnormal. Spindle pole body organization is a process that results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). FYPO_relaxed.owl FYPO:0004620 biolink:NamedThing abnormal spindle disassembly A cellular process phenotype in which spindle disassembly is abnormal. Spindle disassembly is the controlled breakdown of the spindle. FYPO_relaxed.owl FYPO:0004738 biolink:NamedThing abnormal actomyosin contractile ring organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin contractile ring organization is abnormal. The process normally results in the assembly, arrangement of constituent parts, or disassembly of the actomyosin contractile ring. FYPO_relaxed.owl FYPO:0005273 biolink:NamedThing abnormal cell cycle phase transition A cellular process phenotype in which a cell does not execute a cell cycle phase transition normally. FYPO_relaxed.owl FYPO:0006479 biolink:NamedThing abnormal cohesin loading A cell phenotype in which cohesin loading is abnormal. Cohesin loading is the topological linking of a cohesin ring complex to chromatin. FYPO_relaxed.owl FYPO:0006521 biolink:NamedThing abnormal mitotic sister chromatid cohesion A cellular process phenotype in which mitotic sister chromatid cohesion is abnormal. Mitotic sister chromatid cohesion is the process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. FYPO_relaxed.owl FYPO:0007860 biolink:NamedThing spindle pole body separation in absence of mitotic spindle A cellular process phenotype in which the spindle pole body (SPB) duplicates normally, and the SPBs separate, in a cell that does not form a mitotic spindle or undergo cytokinesis. The DNA and nucleus may go on to divide in the absence of a spindle, with each DNA mass associated with an SPB. FYPO_relaxed.owl FYPO:0007861 biolink:NamedThing sister chromatid separation during nuclear fission A cellular process phenotype in which sister chromatids become physically detached in a cell that does not form a mitotic spindle or undergo cytokinesis. The DNA and nucleus may go on to divide in the absence of a spindle, with sister chromatids segregated to separate DNA masses. FYPO_relaxed.owl FYPO:0007862 biolink:NamedThing centromere clustering at nuclear periphery during nuclear division in absence of mitotic spindle A cellular process phenotype in which centromeres and kinetochores remain associated with the spindle pole body during nuclear division in a that does not form a mitotic spindle or undergo cytokinesis. FYPO_relaxed.owl FYPO:0000030 biolink:NamedThing abnormal mitotic chromosome congression A cellular process phenotype in which chromosome congression is abnormal during mitosis. Chromosome congression is the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle. FYPO_relaxed.owl FYPO:0000141 biolink:NamedThing abnormal mitotic sister chromatid segregation A cellular process phenotype in which mitotic sister chromatid segregation is abnormal. Mitotic sister chromatid segregation is the entire process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. FYPO_relaxed.owl FYPO:0000131 biolink:NamedThing abnormal mitotic spindle elongation A spindle phenotype in which mitotic spindle elongation, i.e. the process of lengthening the distance between poles of the mitotic spindle, is abnormal. FYPO_relaxed.owl FYPO:0000177 biolink:NamedThing abnormal mitotic spindle assembly A cellular process phenotype in which assembly of the mitotic spindle is abnormal. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle. FYPO_relaxed.owl FYPO:0000214 biolink:NamedThing abnormal mitotic chromosome condensation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation is abnormal. FYPO_relaxed.owl FYPO:0000227 biolink:NamedThing chromosome loss during mitotic chromosome segregation A chromosome segregation phenotype observed in the vegetative growth phase of the life cycle in which one or more chromosome or minichromosome is not correctly segregated to either daughter cells during mitosis. FYPO_relaxed.owl FYPO:0000228 biolink:NamedThing lagging mitotic chromosomes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which sister chromatids do not move towards the spindle poles at the same time during mitosis, but instead one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated. Mitotic sister chromatid segregation may stop before completing separation of chromosomes, or may eventually be completed. FYPO_relaxed.owl FYPO:0000229 biolink:NamedThing cut An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes septation despite abnormal mitotic nuclear division, such that the septum physically divides the nucleus into two parts, giving rise to inviable daughter cells. FYPO_relaxed.owl FYPO:0000283 biolink:NamedThing mitotic chromosome fragmentation upon segregation A chromosome segregation phenotype in which chromosomes are broken during mitotic chromosome segregation. FYPO_relaxed.owl FYPO:0000415 biolink:NamedThing decreased mitotic sister chromatid segregation A cellular process phenotype in which the occurrence of mitotic sister chromatid segregation is decreased. FYPO_relaxed.owl FYPO:0000670 biolink:NamedThing abnormal mitotic sister chromatid separation A cellular process phenotype in which mitotic sister chromatid separation is abnormal. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis. FYPO_relaxed.owl FYPO:0003241 biolink:NamedThing unequal mitotic sister chromatid segregation A cellular process phenotype in which mitotic sister chromatid segregation fails to separate chromosomes into two equal masses. Unequal mitotic sister chromatid separation may be complete, with two distinct unequal DNA masses located at or near the ends of an elongated mitotic spindle, or incomplete. FYPO_relaxed.owl FYPO:0003757 biolink:NamedThing incomplete mitotic sister chromatid segregation A cellular process phenotype in which mitotic sister chromatid segregation stops before completing separation of chromosomes; some, but not all, DNA may be moved towards the ends of an elongated mitotic spindle. FYPO_relaxed.owl FYPO:0003760 biolink:NamedThing inviable after spore germination, single or double cell division, arrest with cut A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and all cells produced arrest the cell cycle with a cut phenotype, and then die. FYPO_relaxed.owl FYPO:0003843 biolink:NamedThing inviable following spore germination, single cell division, unequal chromosome segregation A phenotype in which a spore germinates to produce a cell that undergoes a single round of cell division during which chromosomes segregate unequally, and then dies. FYPO_relaxed.owl FYPO:0006524 biolink:NamedThing premature sister kinetochore separation during mitotic G2 phase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which sister kinetochores separate during G2 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0000489 biolink:NamedThing abnormal mitochondrial distribution A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion distribution is abnormal. FYPO_relaxed.owl FYPO:0000521 biolink:NamedThing abnormal peroxisome localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisome localization is abnormal. FYPO_relaxed.owl FYPO:0001338 biolink:NamedThing abnormal nucleus positioning during vegetative growth A cellular process phenotype in which nucleus localization is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001515 biolink:NamedThing abnormal telomere tethering at nuclear periphery during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere tethering at the nuclear periphery is abnormal. FYPO_relaxed.owl FYPO:0001778 biolink:NamedThing abnormal centromere localization A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of one or more centromere(s) is abnormal. FYPO_relaxed.owl FYPO:0002872 biolink:NamedThing abnormal endoplasmic reticulum localization A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of the endoplasmic reticulum (ER) is abnormal. In fission yeast, the ER is normally located in the cell cortex and tethered to the plasma membrane. FYPO_relaxed.owl FYPO:0005348 biolink:NamedThing abnormal spindle pole body-led chromosome movement during mitotic interphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body (SPB)-led chromosome movement is abnormal. SPB-led chromosome movement is a microtubule-based process in which chromosomes migrate as a result of rapid spindle pole body (SPB) and centrosome oscillations during mitotic interphase. FYPO_relaxed.owl FYPO:0006330 biolink:NamedThing decreased endoplasmic reticulum-plasma membrane tethering A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the attachment of an endoplasmic reticulum membrane to the plasma membrane via molecular tethers occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007128 biolink:NamedThing abnormal mitotic chromosome movement towards spindle pole A cellular process phenotype in which movement of chromosomes from the center of the mitotic spindle towards the spindle poles is abnormal. This normally takes place during mitotic anaphase A. FYPO_relaxed.owl FYPO:0008009 biolink:NamedThing abnormal interphase mitotic telomere clustering during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere clustering is abnormal. Telomere clustering gathers telomeres during or prior to tethering to the nuclear periphery during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0008127 biolink:NamedThing ribosome mislocalized to nucleoplasm A cell phenotype where a ribosome is mislocalized to the nucleoplasm in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000031 biolink:NamedThing abnormal mating A cellular process phenotype in which conjugation is abnormal. Conjugation, also known as mating, is a process that results in the union of cellular and genetic information from cells of compatible mating types. FYPO_relaxed.owl FYPO:0000301 biolink:NamedThing mating phenotype A biological process phenotype that affects conjugation. FYPO_relaxed.owl FYPO:0000760 biolink:NamedThing normal mating A cellular process phenotype in which conjugation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005447 biolink:NamedThing abnormal biological process A phenotype in which a specific biological process is abnormal. FYPO_relaxed.owl FYPO:0000154 biolink:NamedThing abnormal negative regulation of G0 to G1 transition A regulation phenotype in which negative regulation of the G0 to G1 transition is abnormal. FYPO_relaxed.owl FYPO:0000165 biolink:NamedThing abnormal regulation of mating A regulation phenotype in which regulation of conjugation is abnormal. FYPO_relaxed.owl FYPO:0000178 biolink:NamedThing abnormal regulation of cytokinesis A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of cytokinesis is abnormal. FYPO_relaxed.owl FYPO:0000184 biolink:NamedThing abnormal regulation of pseudohyphal growth A regulation phenotype in which regulation of pseudohyphal growth is abnormal. FYPO_relaxed.owl FYPO:0000191 biolink:NamedThing abnormal regulation of establishment or maintenance of cell polarity A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of the establishment or maintenance of cell polarity is abnormal. FYPO_relaxed.owl FYPO:0000202 biolink:NamedThing abnormal regulation of cytokinetic cell separation A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of cytokinetic cell separation is abnormal. FYPO_relaxed.owl FYPO:0000468 biolink:NamedThing abnormal mating type switching A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mating type switching is abnormal. FYPO_relaxed.owl FYPO:0000680 biolink:NamedThing abnormal ascus development A developmental process phenotype in which ascus development is abnormal. FYPO_relaxed.owl FYPO:0000682 biolink:NamedThing abnormal regulation of molecular function A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of a molecular function is abnormal. FYPO_relaxed.owl FYPO:0001184 biolink:NamedThing abnormal maltase activity A molecular function phenotype in which the observed rate of maltose alpha-glucosidase (also known as maltase) activity is abnormal. FYPO_relaxed.owl FYPO:0001356 biolink:NamedThing abnormal vegetative cell population growth A cellular process phenotype in which vegetative cell population growth is abnormal. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide. FYPO_relaxed.owl FYPO:0001392 biolink:NamedThing abnormal regulation of cell growth A regulation phenotype in which regulation of vegetative cell growth is abnormal. FYPO_relaxed.owl FYPO:0002261 biolink:NamedThing abnormal N-glycan processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which N-glycan processing is abnormal. FYPO_relaxed.owl FYPO:0004526 biolink:NamedThing abnormal regulation of transcription A transcription regulation phenotype in which any process of regulation of transcription is abnormal. FYPO_relaxed.owl FYPO:0004756 biolink:NamedThing abnormal regulation of DNA replication initiation A regulation phenotype in which regulation of the initiation of DNA-dependent DNA replication is abnormal. FYPO_relaxed.owl FYPO:0005448 biolink:NamedThing abolished biological process A phenotype in which a specific biological process does not occur. FYPO_relaxed.owl FYPO:0006201 biolink:NamedThing abnormal regulation of adenine biosynthetic process A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of an adenine biosynthetic process is abnormal. FYPO_relaxed.owl FYPO:0006474 biolink:NamedThing abnormal regulation of translation in response to amino acid starvation A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to starvation for one or more amino acids is abnormal. FYPO_relaxed.owl FYPO:0006790 biolink:NamedThing meiotic drive suppression A biological process phenotype in which meiotic drive occurs to a lower extent than normal, or does not occur at all, despite the presence of a gene or allele that normally causes drive. Meiotic drive results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to such that are unequally represented (i.e. the "driver" is overrepresented) among the surviving products of meiosis. FYPO_relaxed.owl FYPO:0006793 biolink:NamedThing altered meiotic drive suppression specificity A biological process phenotype in which the specificity between a meiotic driver gene and a drive suppressor gene differs from that observed when both genes are wild type. Meiotic drive results in the unequal transmission of alleles, haplotypes, or chromosomes from a parental genome to such that are unequally represented (i.e. the "driver" is overrepresented) among the surviving products of meiosis. FYPO_relaxed.owl FYPO:0007418 biolink:NamedThing abnormal telomere localization A cellular process phenotype in which telomere localization, a process in which a telomere is transported to, and/or maintained in, a specific location, is abnormal. FYPO_relaxed.owl FYPO:0000032 biolink:NamedThing abnormal cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytokinesis is abnormal. Cytokinesis is part of the cell cycle and results in the division of the cytoplasm of a cell and its separation into two daughter cells. FYPO_relaxed.owl FYPO:0000164 biolink:NamedThing abnormal cell separation after cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis is abnormal. Cell separation is the process of physically separating progeny cells after cytokinesis is complete, and involves enzymatic digestion of septum components. FYPO_relaxed.owl FYPO:0000337 biolink:NamedThing abnormal mitosis A cellular process phenotype in which mitosis is abnormal. FYPO_relaxed.owl FYPO:0002029 biolink:NamedThing abnormal cell division, large and small daughter cells A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a cell divides asymmetrically, resulting in the formation of daughter cells that are not the same size. FYPO_relaxed.owl FYPO:0001026 biolink:NamedThing abnormal occurrence of normal mitotic cell cycle arrest A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs is abnormal (does not occur, or occurs abnormally). FYPO_relaxed.owl FYPO:0001343 biolink:NamedThing abnormal mitotic DNA replication A cellular process phenotype in which DNA replication is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001704 biolink:NamedThing abnormal mitotic cell cycle checkpoint A cell cycle phenotype in which a specific mitotic cell cycle checkpoint is abnormal. A cell cycle checkpoint normally controls cell cycle progression by monitoring the timing and integrity of specific cell cycle events. In a mutant, the checkpoint may fail to activate under appropriate conditions, or may occur to a greater or lesser extent than wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0001779 biolink:NamedThing abnormal centromere clustering at nuclear periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of centromeres and associated kinetochores into a cluster at the nuclear periphery is abnormal. Centromere-kinetochore complexes normally cluster near the old spindle pole body during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0001791 biolink:NamedThing abnormal mitotic spindle pole body duplication A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle pole body duplication is abnormal. FYPO_relaxed.owl FYPO:0003567 biolink:NamedThing abnormal mitotic spindle pole body insertion into nuclear envelope A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the insertion of the mitotic spindle pole body localization into the nuclear envelope is abnormal. FYPO_relaxed.owl FYPO:0004621 biolink:NamedThing abnormal mitotic spindle disassembly A cellular process phenotype in which disassembly of the mitotic spindle is abnormal. FYPO_relaxed.owl FYPO:0005275 biolink:NamedThing abnormal mitotic cell cycle phase transition A cellular process phenotype in which a cell does not execute a mitotic cell cycle phase transition normally. FYPO_relaxed.owl FYPO:0005556 biolink:NamedThing abolished mitotic cohesin loading A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin loading does not occur during the mitotic cell cycle. Cohesin loading is the topological linking of a cohesin ring complex to chromatin. FYPO_relaxed.owl FYPO:0007127 biolink:NamedThing abnormal actomyosin contractile ring maturation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin contractile ring maturation is abnormal. FYPO_relaxed.owl FYPO:0000033 biolink:NamedThing abnormal actomyosin contractile ring localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring localization is abnormal. Actomyosin contractile ring localization is the part of cytokinesis in which the actomyosin contractile ring is assembled and/or maintained in a specific location. FYPO_relaxed.owl FYPO:0000117 biolink:NamedThing abnormal septum assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septum assembly is abnormal. FYPO_relaxed.owl FYPO:0000161 biolink:NamedThing abnormal actomyosin contractile ring assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring assembly is abnormal. Contractile ring assembly is the part of cytokinesis in which the actomyosin contractile ring is formed of actin, myosin, and associated proteins. FYPO_relaxed.owl FYPO:0000230 biolink:NamedThing abnormal actomyosin contractile ring actin filament organization A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of actin filaments and associated proteins does not occur normally, resulting in the formation of an abnormal actomyosin contractile ring in which actin is absent or mislocalized. FYPO_relaxed.owl FYPO:0000231 biolink:NamedThing abnormal actomyosin contractile ring myosin filament organization A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which myosin filaments are not localized normally within the actomyosin contractile ring. FYPO_relaxed.owl FYPO:0000418 biolink:NamedThing decreased cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitotic cytokinesis is decreased. FYPO_relaxed.owl FYPO:0000419 biolink:NamedThing decreased rate of cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic cytokinesis is decreased. FYPO_relaxed.owl FYPO:0000420 biolink:NamedThing delayed onset of cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic cytokinesis begins later than normal. FYPO_relaxed.owl FYPO:0001364 biolink:NamedThing abnormal actomyosin contractile ring contraction A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction is abnormal. Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts. FYPO_relaxed.owl FYPO:0001904 biolink:NamedThing premature actomyosin contractile ring disassembly A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the contractile ring collapses or disassembles upon initiation of contraction during anaphase B. Septum formation typically does not occur in cells in which the contractile ring has collapsed. FYPO_relaxed.owl FYPO:0002560 biolink:NamedThing abnormal protein localization to actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is abnormal. FYPO_relaxed.owl FYPO:0003013 biolink:NamedThing abnormal actomyosin contractile ring disassembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring disassembly is abnormal. Contractile ring disassembly is the part of cytokinesis in which the actomyosin contractile ring is disaggregated into its constituent components. FYPO_relaxed.owl FYPO:0003443 biolink:NamedThing decreased medial cortical node movement during contractile ring assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which medial cortical nodes move less frequently, and over shorter distances, than normal. During contractile ring assembly, medial cortical nodes normally move towards the cell center, and condense into a ring. FYPO_relaxed.owl FYPO:0003444 biolink:NamedThing abnormal medial cortical node condensation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which medial cortical nodes move in random directions such that they do not undergo an overall movement towards the cell center. During contractile ring assembly, medial cortical nodes normally move towards the cell center, and condense into a ring. FYPO_relaxed.owl FYPO:0004428 biolink:NamedThing increased rate of cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic cytokinesis is increased. FYPO_relaxed.owl FYPO:0004882 biolink:NamedThing cytokinesis in presence of assembled mitotic spindle A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytokinesis takes place before the mitotic spindle has disassembled. As a result, the contractile ring cuts through the spindle. FYPO_relaxed.owl FYPO:0005289 biolink:NamedThing actomyosin contractile ring sliding A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the maintenance of the mitotic actomyosin contractile ring in the correct location is abnormal. FYPO_relaxed.owl FYPO:0005839 biolink:NamedThing increased rate of medial membrane band assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of medial membrane band assembly is increased. Medial membrane band assembly is the assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring. FYPO_relaxed.owl FYPO:0005874 biolink:NamedThing decreased rate of medial membrane band assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of medial membrane band assembly is decreased. Medial membrane band assembly is the assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring. FYPO_relaxed.owl FYPO:0001337 biolink:NamedThing localization phenotype during vegetative growth A cell phenotype that affects the localization of a structure or substance in a cell in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000190 biolink:NamedThing abnormal actin cortical patch localization during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch localization is abnormal. FYPO_relaxed.owl FYPO:0000443 biolink:NamedThing abnormal protein localization during vegetative growth A cell phenotype that affects the localization of a protein in a cell in the vegetative growth phase of the life cycle. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. FYPO_relaxed.owl FYPO:0000644 biolink:NamedThing normal protein localization during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular protein localization is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001336 biolink:NamedThing transport phenotype during vegetative growth A cell process phenotype that affects a transport process in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001870 biolink:NamedThing normal centromere clustering at nuclear periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of centromeres and associated kinetochores into a cluster at the nuclear periphery is normal (i.e. indistinguishable from wild type). Centromere-kinetochore complexes normally cluster near the old spindle pole body during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004924 biolink:NamedThing normal telomere tethering at nuclear periphery A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere tethering at the nuclear periphery is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006005 biolink:NamedThing normal actomyosin contractile ring localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring localization is normal (i.e. indistinguishable from wild type). Actomyosin contractile ring localization is the part of cytokinesis in which the actomyosin contractile ring is assembled and/or maintained in a specific location. FYPO_relaxed.owl FYPO:0006121 biolink:NamedThing abnormal membrane raft distribution A cell phenotype observed in the vegetative growth phase of the life cycle in which membrane raft distribution, i.e. the process that establishes the spatial arrangement of membrane rafts within a cellular membrane, is abnormal. FYPO_relaxed.owl FYPO:0006216 biolink:NamedThing normal establishment of actomyosin contractile ring localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which establishment of actomyosin contractile ring localization is normal (i.e. indistinguishable from wild type). Establishment of actomyosin contractile ring localization is the part of cytokinesis in which the actomyosin contractile ring is assembled in a specific location. FYPO_relaxed.owl FYPO:0006545 biolink:NamedThing abnormal membrane lipid distribution A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of one or more lipids in a cellular membrane is abnormal. FYPO_relaxed.owl FYPO:0006546 biolink:NamedThing normal membrane lipid distribution A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of one or more lipids in a cellular membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007269 biolink:NamedThing normal interphase mitotic telomere clustering during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere clustering is normal (i.e. indistinguishable from wild type). Telomere clustering gathers telomeres during or prior to tethering to the nuclear periphery during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007913 biolink:NamedThing normal organelle localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which organelle localization is normal. FYPO_relaxed.owl FYPO:0000034 biolink:NamedThing abnormal endocytosis during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis is abnormal. Endocytosis is a vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0000171 biolink:NamedThing abnormal late endosome to vacuole transport A transport phenotype observed in the vegetative growth phase of the life cycle in which late endosome to vacuole transport is abnormal. FYPO_relaxed.owl FYPO:0002089 biolink:NamedThing abnormal exocytosis during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which exocytosis is abnormal. Exocytosis is the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. A phenotype may affect exocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0007056 biolink:NamedThing abnormal post-Golgi vesicle-mediated transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of substances via vesicles from the Golgi to other parts of the cell is abnormal.. FYPO_relaxed.owl FYPO:0007057 biolink:NamedThing abnormal recycling endosome to Golgi transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of substances via vesicles from recycling endosomes to the Golgi is abnormal. FYPO_relaxed.owl FYPO:0007721 biolink:NamedThing abnormal protein recycling from late endosome to Golgi A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of proteins via vesicles from late endosomes to the Golgi is abnormal. This process is normally mediated by the retromer complex. FYPO_relaxed.owl FYPO:0003886 biolink:NamedThing abnormal endocytosis A cellular process phenotype in which endocytosis is abnormal. Endocytosis is a vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0004446 biolink:NamedThing decreased endocytosis during meiotic cell cycle A cellular process phenotype in which the occurrence of endocytosis is decreased during the meiotic cell cycle. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0006384 biolink:NamedThing decreased rate of endocytosis during nitrogen starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of endocytosis is decreased when the cell is subject to nitrogen starvation. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0000042 biolink:NamedThing growth auxotrophic for sulfite Auxotrophy in which a cell requires sulfite in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0003270 biolink:NamedThing growth auxotrophic for glutathione Auxotrophy in which a cell is unable to synthesize glutathione, and therefore requires glutathione in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0003816 biolink:NamedThing growth auxotrophic for histidine or lysine Auxotrophy in which a cell requires histidine or lysine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0008092 biolink:NamedThing growth auxotrophic for para-hydroxy benzoic acid Auxotrophy in which a cell is unable to synthesize para-hydroxy benzoic acid and therefore requires para-hydroxy benzoic acid in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0000037 biolink:NamedThing growth auxotrophic for cysteine Auxotrophy in which a cell is unable to synthesize cysteine, and therefore requires cysteine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0000040 biolink:NamedThing growth auxotrophic for methionine Auxotrophy in which a cell is unable to synthesize methionine, and therefore requires methionine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0000043 biolink:NamedThing abnormal glucan synthesis during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which glucan biosynthesis is abnormal. FYPO_relaxed.owl FYPO:0001331 biolink:NamedThing cellular process phenotype during vegetative growth A phenotype that affects a cellular process in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000739 biolink:NamedThing cellular pigment accumulation phenotype A cellular process phenotype that affects the occurrence of pigment accumulation in a cell. FYPO_relaxed.owl FYPO:0001319 biolink:NamedThing normal cellular process during vegetative growth A phenotype in which a specific cellular process is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001334 biolink:NamedThing regulation phenotype during vegetative growth A cellular process phenotype that affects the regulation of a molecular function, biological process, or biological quality in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001342 biolink:NamedThing cellular response phenotype during vegetative growth A cellular process phenotype that affects a response to a stimulus in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001348 biolink:NamedThing cellular metabolism phenotype during vegetative growth A cellular process phenotype that affects metabolism in the cell in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0004683 biolink:NamedThing unequal nucleolus inheritance A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the nucleolus is partitioned to daughter cells unequally during cell division. FYPO_relaxed.owl FYPO:0007905 biolink:NamedThing abnormal beta-glucan synthesis A cellular process phenotype in which beta-glucan biosynthesis is abnormal. FYPO_relaxed.owl FYPO:0000044 biolink:NamedThing abnormal negative regulation of transcription by glucose A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by glucose (glucose repression) is abnormal. For example, specific genes that are normally not transcribed in the presence of glucose may be transcribed in the mutant. FYPO_relaxed.owl FYPO:0000624 biolink:NamedThing abnormal negative regulation of transcription during vegetative growth A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which any process of negative regulation of transcription is abnormal. FYPO_relaxed.owl FYPO:0000144 biolink:NamedThing abnormal chromatin silencing A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is abnormal. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core). FYPO_relaxed.owl FYPO:0002893 biolink:NamedThing decreased repression of transcription during cellular response to cAMP A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription from RNA polymerase II promoter occurs to a lower extent than normal during a cellular response to cAMP. Specific genes are more highly transcribed in the presence of cAMP in the mutant than in wild type. FYPO_relaxed.owl FYPO:0003008 biolink:NamedThing decreased repression of transcription during cellular response to zinc A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription from RNA polymerase II promoter occurs to a lower extent than normal during a cellular response to zinc. Specific genes are more highly transcribed in the presence of zinc in the mutant than in wild type. FYPO_relaxed.owl FYPO:0007091 biolink:NamedThing increased negative regulation of transcription by zinc A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by zinc occurs to a greater extent than normal. Specific genes that are normally not transcribed in the presence of zinc ions are not derepressed in the mutant under conditions that derepress transcription in wild type cells. FYPO_relaxed.owl FYPO:0001481 biolink:NamedThing alpha,alpha-trehalase activity increase abolished during cellular response to nutrient A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity does not increase as a result of a nutrient stimulus. FYPO_relaxed.owl FYPO:0002663 biolink:NamedThing alpha,alpha-trehalase activity increase abolished during cellular response to hydrogen peroxide A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity does not increase as a result of a hydrogen peroxide stimulus. FYPO_relaxed.owl FYPO:0000045 biolink:NamedThing abnormal cell population growth A cell population phenotype in which a population of cells grow abnormally. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide. FYPO_relaxed.owl FYPO:0000139 biolink:NamedThing cell population growth phenotype A cell phenotype that affects the rate or extent of cell population growth. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide. FYPO_relaxed.owl FYPO:0000047 biolink:NamedThing normal cell population growth A cell population phenotype in which a population of cells grow normally (i.e. indistinguishably from wild type). Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide. FYPO_relaxed.owl FYPO:0001358 biolink:NamedThing vegetative cell population growth phenotype A cell phenotype that affects the rate or extent of cell population growth in the vegetative growth phase of the life cycle. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide. FYPO_relaxed.owl FYPO:0000114 biolink:NamedThing cellular process phenotype A phenotype that affects a cellular process. FYPO_relaxed.owl FYPO:0000155 biolink:NamedThing increased flocculation A cell population phenotype that reflects increased occurrence of flocculation. Flocculation is the non-sexual aggregation of single cells. FYPO_relaxed.owl FYPO:0000679 biolink:NamedThing developmental process phenotype A phenotype that affects a developmental process. FYPO_relaxed.owl FYPO:0007790 biolink:NamedThing normal hyphal growth A phenotype in which hyphal growth is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000150 biolink:NamedThing abnormal colony morphology A cell population phenotype in which the morphology, i.e. the size, shape, or structure, of a colony growing on a solid surface is abnormal. FYPO_relaxed.owl FYPO:0000240 biolink:NamedThing abnormal filament morphology A cell population phenotype in which the size, shape, or structure of invasively growing filaments is abnormal. FYPO_relaxed.owl FYPO:0000244 biolink:NamedThing loss of viability upon nutrient depletion A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells are deprived of nutrients such as carbon or nitrogen. FYPO_relaxed.owl FYPO:0000245 biolink:NamedThing loss of viability in stationary phase A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after entering stationary phase. FYPO_relaxed.owl FYPO:0000303 biolink:NamedThing decreased conjugation frequency A cell population phenotype in which a smaller than normal proportion of cells in the population undergoes conjugation. FYPO_relaxed.owl FYPO:0000376 biolink:NamedThing decreased frequency of apoptosis A cell population phenotype in which the frequency of occurrence of apoptosis is decreased. Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. FYPO_relaxed.owl FYPO:0000377 biolink:NamedThing increased frequency of apoptosis A cell population phenotype in which the frequency of occurrence of apoptosis is increased. Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. FYPO_relaxed.owl FYPO:0000476 biolink:NamedThing decreased frequency of meiosis A cell population phenotype in which the frequency of occurrence of one or both meiotic nuclear division(s) is decreased. FYPO_relaxed.owl FYPO:0000581 biolink:NamedThing decreased spore germination frequency A cell population phenotype in which the frequency of occurrence of spore germination is decreased. FYPO_relaxed.owl FYPO:0000584 biolink:NamedThing decreased sporulation frequency A cell population phenotype in which the frequency of occurrence of ascospore formation is decreased. FYPO_relaxed.owl FYPO:0000588 biolink:NamedThing increased sporulation frequency A cell population phenotype in which the frequency of occurrence of ascospore formation is increased. FYPO_relaxed.owl FYPO:0000650 biolink:NamedThing increased septation index A cell population phenotype in which the septation index is higher than normal. The septation index is the proportion of the population undergoing septation at any given time, and is usually around 10% (varying between 7-15%) for wild type. FYPO_relaxed.owl FYPO:0000707 biolink:NamedThing abnormal molecular function A phenotype in which a specific molecular function is abnormal. FYPO_relaxed.owl FYPO:0000708 biolink:NamedThing decreased mating efficiency A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is lower than normal. FYPO_relaxed.owl FYPO:0000761 biolink:NamedThing increased conjugation frequency A cell population phenotype in which a larger than normal proportion of cells in the population undergoes conjugation. FYPO_relaxed.owl FYPO:0001043 biolink:NamedThing increased mating efficiency A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is higher than normal. FYPO_relaxed.owl FYPO:0001128 biolink:NamedThing decreased septation index A cell population phenotype in which the septation index is lower than normal. The septation index is the proportion of the population undergoing septation at any given time, and is usually around 10% (varying between 7-15%) for wild type. FYPO_relaxed.owl FYPO:0001155 biolink:NamedThing altered effect on growth medium A phenotype in which the changes that take place in growth medium, due to metabolism, secretion, etc. by a cell or population of cells, differs from normal. FYPO_relaxed.owl FYPO:0001187 biolink:NamedThing decreased cell density in stationary phase A cell population phenotype in which a population reaches stationary phase at, and maintains, a lower cell density than wild type. FYPO_relaxed.owl FYPO:0001309 biolink:NamedThing increased viability in stationary phase A cell population phenotype in which a larger than normal proportion of cells in the population remains viable after entering stationary phase. FYPO_relaxed.owl FYPO:0001387 biolink:NamedThing loss of viability at high temperature A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells are grown at a temperature higher than standard. FYPO_relaxed.owl FYPO:0001821 biolink:NamedThing increased number of heterothallic h+ cells A cell population phenotype in which a greater than normal number of cells in an originally homothallic (h90) population express P-specific information from the mat1 locus. FYPO_relaxed.owl FYPO:0001942 biolink:NamedThing increased duration of lag phase A cell population phenotype in which a population in a culture remains in lag phase longer than normal. The onset of exponential growth is thus delayed. FYPO_relaxed.owl FYPO:0001974 biolink:NamedThing increased number of cells with 1C DNA content A cell population phenotype in which a greater than normal number of cells contain 1C DNA content. This may result from cell cycle arrest or delay. FYPO_relaxed.owl FYPO:0002929 biolink:NamedThing abnormal poly(A) tail length A phenotype in which polyadenylated RNA molecules have poly(A) tails of abnormal length. FYPO_relaxed.owl FYPO:0003048 biolink:NamedThing abnormal transcript length A phenotype in which a transcript, i.e. an RNA molecule synthesized on a DNA template by RNA polymerase, has an abnormal length. FYPO_relaxed.owl FYPO:0003093 biolink:NamedThing increased Argonaute-associated RNA length A phenotype in which small RNA molecules physically associated with the Argonaute protein (Ago1) are longer than normal. FYPO_relaxed.owl FYPO:0003290 biolink:NamedThing abnormal glycoprotein glycan structure A phenotype in which the structure of the glycan moiety of a glycoprotein differs from wild type. FYPO_relaxed.owl FYPO:0003306 biolink:NamedThing decreased mitotic index A cell population phenotype in which the mitotic index is lower than normal. The mitotic index is the proportion of the population undergoing mitosis at any given time. FYPO_relaxed.owl FYPO:0003307 biolink:NamedThing increased mitotic index A cell population phenotype in which the mitotic index is higher than normal. The mitotic index is the proportion of the population undergoing mitosis at any given time. FYPO_relaxed.owl FYPO:0003324 biolink:NamedThing altered cytochrome absorption spectrum A phenotype in which the spectrum of light absorption observed in whole cells or isolated mitochondria, and attributed to cytochromes present, differs from wild type. FYPO_relaxed.owl FYPO:0003427 biolink:NamedThing decreased queuosine level in tRNA A phenotype in which one or more transfer RNA (tRNA) molecules contains fewer queuosine residues than normal. FYPO_relaxed.owl FYPO:0003532 biolink:NamedThing increased monopolar index A cell population phenotype in which the monopolar index is higher than normal. The monopolar index is the proportion of the population undergoing monopolar growth at any given time. FYPO_relaxed.owl FYPO:0003533 biolink:NamedThing increased bipolar index A cell population phenotype in which the bipolar index is higher than normal. The bipolar index is the proportion of the population undergoing bipolar growth at any given time. FYPO_relaxed.owl FYPO:0003534 biolink:NamedThing decreased monopolar index A cell population phenotype in which the monopolar index is lower than normal. The monopolar index is the proportion of the population undergoing monopolar growth at any given time. FYPO_relaxed.owl FYPO:0003535 biolink:NamedThing decreased bipolar index A cell population phenotype in which the bipolar index is lower than normal. The bipolar index is the proportion of the population undergoing bipolar growth at any given time. FYPO_relaxed.owl FYPO:0003903 biolink:NamedThing loss of viability at low temperature A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells are grown at a temperature lower than standard. FYPO_relaxed.owl FYPO:0004087 biolink:NamedThing increased number of cells with astral spindle microtubules A cell population phenotype in which astral microtubules are present in a greater than normal proportion of the cells that have mitotic spindles. FYPO_relaxed.owl FYPO:0004874 biolink:NamedThing decreased glucose consumption A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of glucose consumed by cells in a given time is lower than normal. FYPO_relaxed.owl FYPO:0004914 biolink:NamedThing abnormal telomeric repeat sequence A phenotype in which the sequence of the telomeric repeating unit differs from normal. FYPO_relaxed.owl FYPO:0004988 biolink:NamedThing abnormal RNA level oscillation during mitotic cell cycle A gene expression phenotype in which RNA levels that normally vary over the course of the mitotic cell cycle do not vary, or change in a pattern different from normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0005153 biolink:NamedThing increased number of heterothallic h- cells A cell population phenotype in which a greater than normal number of cells in an originally homothallic (h90) population express M-specific information from the mat1 locus. FYPO_relaxed.owl FYPO:0005156 biolink:NamedThing abnormal ascus morphology A phenotype characterized by altered ascus morphology, i.e. the size, shape, or structure of the ascus is abnormal. FYPO_relaxed.owl FYPO:0005259 biolink:NamedThing increased cell density in stationary phase A cell population phenotype in which a population reaches stationary phase at, and maintains, a higher cell density than wild type. FYPO_relaxed.owl FYPO:0005456 biolink:NamedThing decreased number of cells with 1C DNA content A cell population phenotype in which a lower than normal number of cells contain 1C DNA content. FYPO_relaxed.owl FYPO:0005704 biolink:NamedThing loss of viability following cellular response to hydroxyurea A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after exposure to hydroxyurea. FYPO_relaxed.owl FYPO:0005705 biolink:NamedThing loss of viability following cellular response to UV A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after exposure to ultraviolet light. FYPO_relaxed.owl FYPO:0005939 biolink:NamedThing decreased replicative lifespan A cell population phenotype in which the replicative lifespan of a cell population, i.e. the number of divisions cells in the population undergo before death, is lower than normal. FYPO_relaxed.owl FYPO:0005940 biolink:NamedThing increased replicative lifespan A cell population phenotype in which the replicative lifespan of a cell population, i.e. the number of divisions cells in the population undergo before death, is higher than normal. FYPO_relaxed.owl FYPO:0006297 biolink:NamedThing increased 5.8S rRNA length A phenotype in which the processed 5.8S ribosomal RNA is longer than normal. FYPO_relaxed.owl FYPO:0006323 biolink:NamedThing loss of viability following replication fork stalling A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after stalled replication forks accumulate. FYPO_relaxed.owl FYPO:0006522 biolink:NamedThing loss of viability following cell cycle arrest at mitotic G2/M phase transition A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after arrest at the mitotic G2/M phase transition of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006537 biolink:NamedThing loss of viability following cellular response to pheromone A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after exposure to a pheromone. FYPO_relaxed.owl FYPO:0006736 biolink:NamedThing stationary phase viability unaffected by tschimganine A cell population phenotype in which the proportion of cells in the population remains viable after entering stationary phase does not change in the presence of tschimganine. Normally, wild-type cell populations survive longer in the presence of tschimganine than in its absence. FYPO_relaxed.owl FYPO:0006737 biolink:NamedThing stationary phase viability unaffected by alpha-hibitakanine A cell population phenotype in which the proportion of cells in the population remains viable after entering stationary phase does not change in the presence of alpha-hibitakanine. Normally, wild-type cell populations survive longer in the presence of alpha-hibitakanine than in its absence. FYPO_relaxed.owl FYPO:0006738 biolink:NamedThing stationary phase viability unaffected by beta-hibitakanine A cell population phenotype in which the proportion of cells in the population remains viable after entering stationary phase does not change in the presence of beta-hibitakanine. Normally, wild-type cell populations survive longer in the presence of beta-hibitakanine than in its absence. FYPO_relaxed.owl FYPO:0006863 biolink:NamedThing loss of viability following cellular response to bleomycin A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after exposure to bleomycin. FYPO_relaxed.owl FYPO:0006902 biolink:NamedThing loss of viability following cellular response to 4-nitroquinoline N-oxide A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after exposure to 4-nitroquinoline N-oxide. FYPO_relaxed.owl FYPO:0007135 biolink:NamedThing increased level of AP sites in DNA A phenotype in which the number of apurinic and ayprimidinic (collectively, AP) sites detected in DNA is greater than normal. An AP is a deoxyribose sugar with a missing base, and is formed by the enzymatic removal of a damaged base. FYPO_relaxed.owl FYPO:0007142 biolink:NamedThing loss of viability following cellular response to ionizing radiation A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after exposure to ionizing radiation. FYPO_relaxed.owl FYPO:0007172 biolink:NamedThing stationary phase viability unaffected by micafungin A cell population phenotype in which the proportion of cells in the population remains viable after entering stationary phase does not change in the presence of micafungin. Normally, wild-type cell populations survive longer in the presence of micafungin than in its absence. FYPO_relaxed.owl FYPO:0007394 biolink:NamedThing abnormal RNA structure A phenotype in which the structure of one or more RNA molecules differs from normal. FYPO_relaxed.owl FYPO:0007431 biolink:NamedThing altered mutation rate A cell phenotype observed in the vegetative growth phase of the life cycle in which mutations occur at a higher or lower rate than normal. FYPO_relaxed.owl FYPO:0007477 biolink:NamedThing abnormal epigenetic heterochromatin inheritance A phenotype in which the stable inheritance of heterochromatic structure is abnormal in regions of the genome where heterochromatin is normally maintained over successive generations. FYPO_relaxed.owl FYPO:0007479 biolink:NamedThing normal epigenetic heterochromatin inheritance A phenotype in which the assembly and stable inheritance of heterochromatic structure is normal (i.e. indistinguishable from wild type) in regions of the genome where heterochromatin is normally maintained over successive generations. FYPO_relaxed.owl FYPO:0007765 biolink:NamedThing abnormal protein level oscillation during mitotic cell cycle A gene expression phenotype in which protein levels that normally vary over the course of the mitotic cell cycle do not vary, or change in a pattern different from normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0000046 biolink:NamedThing decreased cell population growth A cell population phenotype in which cell population growth is decreased relative to normal. Decreased growth may reflect a reduced growth rate (i.e. slower growth), growth that occurs to a lesser extent than normal, or both. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide. FYPO_relaxed.owl FYPO:0002046 biolink:NamedThing resistance to stress A phenotype in which cells in a population show decreased sensitivity to a stress. Typically, a cell population is deemed resistant to a stress if cells in the population grow and divide when exposed to the stress at an intensity at which wild-type cells stop growing (and may die). FYPO_relaxed.owl FYPO:0002549 biolink:NamedThing sensitive to stress A phenotype in which cells in a population show increased sensitivity to a stress. Typically, a cell population is deemed sensitive to a stress if cells in the population stop growing (and may die) when exposed to the stress at an intensity that allows a population of wild type cells to grow and divide. FYPO_relaxed.owl FYPO:0002682 biolink:NamedThing increased resistance to chemical A phenotype in which cells in a population show increased resistance to a chemical stimulus. Resistance to a chemical is usually measured by determining the maximum concentration of the chemical at which a population of cells grow and divide, and cells are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type cells to grow. FYPO_relaxed.owl FYPO:0002683 biolink:NamedThing increased sensitivity to chemical A phenotype in which cells in a population show decreased resistance to a chemical stimulus. Resistance to a chemical is measured by determining the maximum concentration of the chemical at which a population of cells grow and divide. Typically, cells are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003937 biolink:NamedThing increased cell population growth A cell population phenotype in which cell population growth is increased relative to normal. Increased growth may reflect an increased growth rate (i.e. faster growth), growth that occurs to a greater extent than normal, or both. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide. FYPO_relaxed.owl FYPO:0002058 biolink:NamedThing viable cell population A cell population phenotype in which cells in the population are viable. FYPO_relaxed.owl FYPO:0001419 biolink:NamedThing normal cell population growth rate A cell population phenotype in which a population of cells grows at the same rate as wild type. FYPO_relaxed.owl FYPO:0002060 biolink:NamedThing viable vegetative cell population A cell population phenotype in which cells in the population are viable in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0003612 biolink:NamedThing viable spore population A cell population phenotype in which cells in a population of spores are viable. FYPO_relaxed.owl FYPO:0000627 biolink:NamedThing normal cellular process A phenotype in which a specific cellular process is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000706 biolink:NamedThing normal molecular function A phenotype in which a specific molecular function is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001004 biolink:NamedThing viable upon G0 to G1 transition A cell phenotype in which cells to resume growth normally upon exiting G0 phase. FYPO_relaxed.owl FYPO:0001147 biolink:NamedThing normal mating efficiency A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is normal (i.e. the same as in wild-type cells). FYPO_relaxed.owl FYPO:0001310 biolink:NamedThing normal viability in stationary phase A cell population phenotype in which a normal proportion of cells in the population remains viable after entering stationary phase. FYPO_relaxed.owl FYPO:0001312 biolink:NamedThing normal vegetative phenotype A normal phenotype that is observed when cells are in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001903 biolink:NamedThing normal septation index A cell population phenotype in which the septation index is normal (i.e. indistinguishable from wild type). The septation index is the proportion of the population undergoing septation at any given time, and is usually around 10% (varying between 7-15%) for vegetatively growing wild type cell populations, and less for stationary populations. FYPO_relaxed.owl FYPO:0002052 biolink:NamedThing normal sporulation frequency A cell population phenotype in which the frequency of occurrence of ascospore formation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002928 biolink:NamedThing normal poly(A) tail length A phenotype in which polyadenylated RNA molecules have poly(A) tails of normal (i.e. indistinguishable from wild type) length. FYPO_relaxed.owl FYPO:0003736 biolink:NamedThing normal mitotic index A cell population phenotype in which the mitotic index is normal (i.e. indistinguishable from wild type). The mitotic index is the proportion of the population undergoing mitosis at any given time. FYPO_relaxed.owl FYPO:0003861 biolink:NamedThing normal acidification of growth medium in stationary phase A cell population phenotype in which the pH of a growth medium in which a cell population grows to stationary phase decreases to a normal (i.e. indistinguishable from wild type) extent. FYPO_relaxed.owl FYPO:0004165 biolink:NamedThing normal glucose consumption A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of glucose consumed by cells in a given time is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004235 biolink:NamedThing normal RNA level oscillation during mitotic cell cycle A gene expression phenotype in which RNA levels vary over the course of the mitotic cell cycle normally (i.e. levels are indistinguishable from wild type at any assayed point). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0004662 biolink:NamedThing normal viability following cellular response to UV A cell population phenotype in which a normal proportion of cells in the population remains viable after exposure to ultraviolet light. FYPO_relaxed.owl FYPO:0004663 biolink:NamedThing normal viability following cellular response to methyl methanesulfonate A cell population phenotype in which a normal proportion of cells in the population remains viable after exposure to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0004693 biolink:NamedThing normal viability following cellular response to hydroxyurea A cell population phenotype in which a normal proportion of cells in the population remains viable after exposure to hydroxyurea. FYPO_relaxed.owl FYPO:0004720 biolink:NamedThing normal viability following cellular response to heat shock A cell population phenotype in which a normal proportion of cells in the population remains viable after exposure to heat shock. Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature. FYPO_relaxed.owl FYPO:0004915 biolink:NamedThing normal telomeric repeat sequence A phenotype in which the sequence of the telomeric repeating unit is normal (i.e. identical to that found in wild type). FYPO_relaxed.owl FYPO:0004919 biolink:NamedThing normal regulation of molecular function A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of a molecular function is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004942 biolink:NamedThing normal galactose:mannose ratio in glycoprotein glycan A phenotype in which the glycan moiety of a glycoprotein contains galactose and mannose residues in a normal (i.e. indistinguishable from wild type) ratio. In wild-type cells, glycoprotein glycans contain mannose and galactose residues in a 1:1.2 ratio, and the galactose residues are connected by alpha-1,2 linkages. FYPO_relaxed.owl FYPO:0004993 biolink:NamedThing normal spore germination frequency A cell population phenotype in which spore germination occurs at a normal (i.e. indistinguishable from wild type) frequency. FYPO_relaxed.owl FYPO:0005032 biolink:NamedThing normal mutation rate A cell phenotype observed in the vegetative growth phase of the life cycle in which mutations occur at a normal (i.e. indistinguishable from wild type) frequency. FYPO_relaxed.owl FYPO:0005157 biolink:NamedThing normal ascus morphology A phenotype characterized by normal ascus morphology, i.e. the size, shape, and structure of the ascus are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005549 biolink:NamedThing normal viability upon nitrogen starvation A cell population phenotype in which a normal proportion of cells in the population remains viable when cells in a culture are deprived of nitrogen. FYPO_relaxed.owl FYPO:0006565 biolink:NamedThing normal viability upon phosphate starvation A cell population phenotype in which a normal proportion of cells in the population remains viable under conditions of phosphate starvation. FYPO_relaxed.owl FYPO:0006566 biolink:NamedThing normal viability upon sulfur starvation A cell population phenotype in which a normal proportion of cells in the population remains viable under conditions of sulfur starvation. FYPO_relaxed.owl FYPO:0007170 biolink:NamedThing normal number of nuclei in ascus A phenotype an ascus contains four nuclei, as in wild type. FYPO_relaxed.owl FYPO:0007491 biolink:NamedThing normal O-linked glycoprotein glycan structure A phenotype in which the structure of an O-linked glycan moiety of a nascent or mature glycoprotein is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000049 biolink:NamedThing inviable cell A viability phenotype in which a cell is unable to survive under conditions in which wild type cells survive. FYPO_relaxed.owl FYPO:0000124 biolink:NamedThing viable cell A viability phenotype in which a cell is able to survive under the specified conditions. FYPO_relaxed.owl FYPO:0005646 biolink:NamedThing abnormal kinetochore morphology A physical cellular phenotype in which the size, shape, or structure of the kinetochore is abnormal. FYPO_relaxed.owl FYPO:0005647 biolink:NamedThing split kinetochore A physical cellular phenotype in which the kinetochore is divided into two or more parts. FYPO_relaxed.owl FYPO:0000051 biolink:NamedThing abnormal meiosis A cellular process phenotype in which meiosis is abnormal. Meiosis refers specifically to the nuclear division phases of a meiotic cell cycle. FYPO_relaxed.owl FYPO:0000336 biolink:NamedThing abnormal cellular component assembly A cellular process phenotype in which any process of cellular component assembly at the cellular level is abnormal. FYPO_relaxed.owl FYPO:0000510 biolink:NamedThing abnormal nuclear fusion during mating A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion is abnormal. FYPO_relaxed.owl FYPO:0000641 biolink:NamedThing abnormal chromosome organization A cellular process phenotype in which any process of chromosome organization is abnormal. Chromosome organization results in the assembly, arrangement of constituent parts, or disassembly of chromosomes. FYPO_relaxed.owl FYPO:0000802 biolink:NamedThing abnormal cytoskeleton organization A cellular process phenotype in which cytoskeleton organization is abnormal. FYPO_relaxed.owl FYPO:0001013 biolink:NamedThing abnormal membrane organization A cellular process phenotype in which cellular membrane organization is abnormal. Cellular membrane organization results in the assembly, arrangement of constituent parts, or disassembly of a lipid bilayer membrane, such as the plasma membrane or an organelle membrane. FYPO_relaxed.owl FYPO:0002803 biolink:NamedThing abnormal vacuole organization A cellular process phenotype in which vacuole organization is abnormal. Vacuole organization results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. FYPO_relaxed.owl FYPO:0004805 biolink:NamedThing abnormal cell wall organization A cellular process phenotype in which cell wall organization is abnormal. Cell wall organization results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall. FYPO_relaxed.owl FYPO:0006054 biolink:NamedThing decreased lipid droplet formation A cellular process phenotype in which the occurrence of lipid droplet formation is decreased. FYPO_relaxed.owl FYPO:0006945 biolink:NamedThing increased lipid droplet formation A cellular process phenotype in which the occurrence of lipid droplet formation is increased. FYPO_relaxed.owl FYPO:0007274 biolink:NamedThing abnormal mitochondrion inheritance A cellular process phenotype in which mitochondrion inheritance is abnormal. Mitochondrion inheritance is a cellular process that results in the distribution of mitochondria into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton. FYPO_relaxed.owl FYPO:0007590 biolink:NamedThing abnormal mitophagy A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, is abnormal. FYPO_relaxed.owl FYPO:0008083 biolink:NamedThing abnormal reticulophagy A cellular process phenotype in which autophagic degradation of the endoplasmic reticulum is abnormal. FYPO_relaxed.owl FYPO:0008089 biolink:NamedThing abnormal mitochondrial fusion A cellular process phenotype in which mitochondrion fusion is abnormal. FYPO_relaxed.owl FYPO:0000121 biolink:NamedThing abnormal sporulation A cellular process phenotype in which ascospore formation is abnormal. FYPO_relaxed.owl FYPO:0000625 biolink:NamedThing abnormal premeiotic DNA replication A cellular process phenotype in which premeiotic DNA replication is abnormal. FYPO_relaxed.owl FYPO:0002771 biolink:NamedThing abnormal protein localization to meiotic spindle pole body A cell phenotype in which the localization of a protein to the meiotic spindle pole body is abnormal. FYPO_relaxed.owl FYPO:0004272 biolink:NamedThing abnormal ascospore release from ascus A cellular process phenotype in which ascospore release from an ascus is abnormal. FYPO_relaxed.owl FYPO:0005274 biolink:NamedThing abnormal meiotic cell cycle phase transition A cellular process phenotype in which a cell does not execute a meiotic cell cycle phase transition normally. FYPO_relaxed.owl FYPO:0006388 biolink:NamedThing abnormal meiotic spindle pole body organization during meiosis I A cell phenotype in which meiotic spindle pole body organization is abnormal during the first meiotic nuclear division. Meiotic spindle pole body organization is a process that results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body (SPB). FYPO_relaxed.owl FYPO:0006394 biolink:NamedThing abnormal meiotic spindle localization A cellular process phenotype in which localization of the meiotic spindle is abnormal during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0006568 biolink:NamedThing abnormal meiotic mismatch repair A cellular process phenotype in which meiotic mismatch repair is abnormal. Meiotic mismatch repair is the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. FYPO_relaxed.owl FYPO:0006759 biolink:NamedThing abnormal meiotic chromosome organization A cellular process phenotype in which chromosome organization is abnormal during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0000052 biolink:NamedThing abnormal meiotic cell cycle A cellular process phenotype in which a cell does not proceed normally through a meiotic cell cycle. FYPO_relaxed.owl FYPO:0000059 biolink:NamedThing abnormal mitotic cell cycle A cellular process phenotype in which a cell does not proceed normally through a mitotic cell cycle. FYPO_relaxed.owl FYPO:0000407 biolink:NamedThing abnormally arrested cell cycle progression A cellular process phenotype in which cell cycle progression is arrested under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0000827 biolink:NamedThing premature cell cycle phase transition A cellular process phenotype in which one or more cell cycle phase transitions begins earlier than normal. FYPO_relaxed.owl FYPO:0002735 biolink:NamedThing abnormal cell cycle phase A cellular process phenotype in which a cell does not proceed normally through a specific cell cycle phase. A cell cycle phase is any of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. FYPO_relaxed.owl FYPO:0000054 biolink:NamedThing abnormal microtubule cytoskeleton organization A phenotype that affects the organization of the microtubule cytoskeleton. Microtubule cytoskeleton organization is a cellular process that results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. FYPO_relaxed.owl FYPO:0000297 biolink:NamedThing microtubule cytoskeleton organization phenotype A cellular process phenotype that affects the organization of the microtubule cytoskeleton. Microtubule cytoskeleton organization results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and associated proteins. FYPO_relaxed.owl FYPO:0001328 biolink:NamedThing abnormal cytoskeleton organization during vegetative growth A cellular process phenotype in which cytoskeleton organization is abnormal in the vegetative growth phase of the cell cycle. FYPO_relaxed.owl FYPO:0004803 biolink:NamedThing abnormal actin cytoskeleton organization A cellular process phenotype in which actin cytoskeleton organization is abnormal. FYPO_relaxed.owl FYPO:0001418 biolink:NamedThing abnormal microtubule cytoskeleton morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the microtubule cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0003625 biolink:NamedThing abnormal microtubule cytoskeleton morphology during mitotic interphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the microtubule cytoskeleton is abnormal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004317 biolink:NamedThing abnormal post-anaphase array morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the post-anaphase array of microtubules is abnormal. FYPO_relaxed.owl FYPO:0006397 biolink:NamedThing cytoplasmic microtubules detached from nuclear envelope A cell phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubules become detached from the nuclear envelope (NE). Normally, some cytoplasmic microtubules are nucleated at the NE and remain attached. FYPO_relaxed.owl FYPO:0000056 biolink:NamedThing mitochondria fused A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which mitochondria have fused into fewer and larger structures than normal, or failed to undergo fission. FYPO_relaxed.owl FYPO:0000359 biolink:NamedThing abnormal mitochondrial morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the mitochondrion is abnormal. FYPO_relaxed.owl FYPO:0003807 biolink:NamedThing net-like mitochondrial morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which mitochondria form branched structures. FYPO_relaxed.owl FYPO:0007193 biolink:NamedThing small fragmented mitochondria A cell phenotype observed in the vegetative growth phase of the life cycle in which mitochondria are smaller than normal. FYPO_relaxed.owl FYPO:0002732 biolink:NamedThing mononucleate cell with increased DNA content during stationary phase A physical cellular phenotype in which a cell contains a single nucleus, and more DNA than normal, when the cell is in a culture in stationary phase. FYPO_relaxed.owl FYPO:0003989 biolink:NamedThing inviable stubby mononucleate vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable and has one nucleus, and the cell diameter is larger than normal and the cell length is shorter than normal. FYPO_relaxed.owl FYPO:0003341 biolink:NamedThing multinucleate A physical cellular phenotype in which a cell contains more than one nucleus. FYPO_relaxed.owl FYPO:0004497 biolink:NamedThing small binucleate cell during stationary phase A cell morphology phenotype in which a cell is smaller than normal and contains two nuclei, when the cell is in a culture in stationary phase. FYPO_relaxed.owl FYPO:0005277 biolink:NamedThing multinucleate multiseptate cell A cell morphology phenotype in which a cell has two or more nuclei and more than one septum per cell. FYPO_relaxed.owl FYPO:0002256 biolink:NamedThing abnormal nuclear morphology A physical cellular phenotype in which the size, shape, or structure of the nucleus is abnormal. FYPO_relaxed.owl FYPO:0002255 biolink:NamedThing enlarged nucleus A physical cellular phenotype in which the nucleus is larger than normal. FYPO_relaxed.owl FYPO:0006661 biolink:NamedThing fragmented nucleus A cell phenotype in which the nucleus is broken into multiple small fragments that are smaller than a normal nucleus. FYPO_relaxed.owl FYPO:0006667 biolink:NamedThing abnormal nuclear morphology during G0 A physical cellular phenotype observed during G0 phase in which the size, shape, or structure of the nucleus is abnormal. FYPO_relaxed.owl FYPO:0008242 biolink:NamedThing abnormal nuclear morphology during meiotic cell cycle A physical cellular phenotype in which the size, shape, or structure of the nucleus is abnormal during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0000293 biolink:NamedThing DNA metabolism phenotype A cellular process phenotype that affects any DNA metabolic process. FYPO_relaxed.owl FYPO:0001346 biolink:NamedThing DNA metabolism phenotype during vegetative growth A cellular process phenotype that affects any DNA metabolic process in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0007606 biolink:NamedThing decreased DNA degradation during nitrogen starvation A cellular process phenotype in which the breakdown of DNA occurs to a lower extent than normal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0000064 biolink:NamedThing resistance to 2-deoxyglucose An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 2-deoxyglucose than normal. FYPO_relaxed.owl FYPO:0000126 biolink:NamedThing increased resistance to chemical during vegetative growth A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased resistance to a chemical stimulus. Resistance to a chemical is usually measured by determining the maximum concentration of the chemical at which a population of cells grow and divide, and cells are deemed resistant to a chemical if they survive at a concentration of the chemical that does not allow wild type cells to grow. FYPO_relaxed.owl FYPO:0000065 biolink:NamedThing resistance to 5-azacytidine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 5-azacytidine than normal. FYPO_relaxed.owl FYPO:0000066 biolink:NamedThing resistance to L-azetidine-2-carboxylic acid An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of L-azetidine-2-carboxylic acid than normal. FYPO_relaxed.owl FYPO:0000067 biolink:NamedThing resistance to brefeldin A An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of brefeldin A than normal. FYPO_relaxed.owl FYPO:0000068 biolink:NamedThing resistance to K-252a An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of K-252a than normal. FYPO_relaxed.owl FYPO:0000069 biolink:NamedThing resistance to thiabendazole An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of thiabendazole than normal. FYPO_relaxed.owl FYPO:0000070 biolink:NamedThing resistance to amphotericin B An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of amphotericin B than normal. FYPO_relaxed.owl FYPO:0000071 biolink:NamedThing resistance to aureobasidin A An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of aureobasidin A than normal. FYPO_relaxed.owl FYPO:0000072 biolink:NamedThing resistance to benomyl An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of benomyl than normal. FYPO_relaxed.owl FYPO:0000073 biolink:NamedThing resistance to caffeine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of caffeine than normal. FYPO_relaxed.owl FYPO:0000075 biolink:NamedThing resistance to lovastatin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of lovastatin than normal. FYPO_relaxed.owl FYPO:0000076 biolink:NamedThing resistance to nystatin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of nystatin than normal. FYPO_relaxed.owl FYPO:0000077 biolink:NamedThing resistance to rapamycin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of rapamycin than normal. FYPO_relaxed.owl FYPO:0000125 biolink:NamedThing resistance to amiloride An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of amiloride than normal. FYPO_relaxed.owl FYPO:0000264 biolink:NamedThing resistance to microtubule-destabilizing substance An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of a microtubule-destabilizing substance than normal. FYPO_relaxed.owl FYPO:0000327 biolink:NamedThing resistance to trichostatin A An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of trichostatin A than normal. FYPO_relaxed.owl FYPO:0000441 biolink:NamedThing resistance to antimycin A An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of antimycin than normal. FYPO_relaxed.owl FYPO:0000724 biolink:NamedThing resistance to N-methyl-N'-nitro-N-nitrosoguanidine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of N-methyl-N'-nitro-N-nitrosoguanidine than normal. FYPO_relaxed.owl FYPO:0000725 biolink:NamedThing resistance to methyl methanesulfonate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of methyl methanesulfonate than normal. FYPO_relaxed.owl FYPO:0000752 biolink:NamedThing resistance to selenate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of selenate ions than normal. FYPO_relaxed.owl FYPO:0000763 biolink:NamedThing resistance to cadmium An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cadmium ions than normal. FYPO_relaxed.owl FYPO:0000764 biolink:NamedThing resistance to cycloheximide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cycloheximide than normal. FYPO_relaxed.owl FYPO:0000765 biolink:NamedThing resistance to leptomycin B An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of leptomycin B than normal. FYPO_relaxed.owl FYPO:0000766 biolink:NamedThing resistance to N-ethylmaleimide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of N-ethylmaleimide than normal. FYPO_relaxed.owl FYPO:0000767 biolink:NamedThing resistance to staurosporine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of staurosporine than normal. FYPO_relaxed.owl FYPO:0000768 biolink:NamedThing resistance to valinomycin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of valinomycin than normal. FYPO_relaxed.owl FYPO:0000829 biolink:NamedThing resistance to cisplatin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cisplatin than normal. FYPO_relaxed.owl FYPO:0000830 biolink:NamedThing resistance to vanadate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of vanadate ions (VO4(3-)) than normal. FYPO_relaxed.owl FYPO:0000831 biolink:NamedThing resistance to actinomycin D An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of actinomycin D than normal. FYPO_relaxed.owl FYPO:0000924 biolink:NamedThing resistance to anisomycin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of anisomycin than normal. FYPO_relaxed.owl FYPO:0001029 biolink:NamedThing resistance to canavanine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of canavanine than normal. FYPO_relaxed.owl FYPO:0001032 biolink:NamedThing resistance to camptothecin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of camptothecin than normal. FYPO_relaxed.owl FYPO:0001034 biolink:NamedThing resistance to tunicamycin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tunicamycin than normal. FYPO_relaxed.owl FYPO:0001103 biolink:NamedThing resistance to hydrogen peroxide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of hydrogen peroxide than normal. FYPO_relaxed.owl FYPO:0001109 biolink:NamedThing resistance to menadione An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of menadione than normal. FYPO_relaxed.owl FYPO:0001379 biolink:NamedThing resistance to tacrolimus An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tacrolimus than normal. FYPO_relaxed.owl FYPO:0001431 biolink:NamedThing resistance to Dio-9 An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of the antibiotic Dio-9 than normal. FYPO_relaxed.owl FYPO:0001432 biolink:NamedThing resistance to ethidium bromide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethidium bromide than normal. FYPO_relaxed.owl FYPO:0001433 biolink:NamedThing resistance to decamethylenediguanidine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of decamethylenediguanidine than normal. FYPO_relaxed.owl FYPO:0001434 biolink:NamedThing resistance to N,N'-(p-xylylidene)bis-aminoguanidine 2HCl An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of N,N'-(p-xylylidene)bis-aminoguanidine 2HCl than normal. FYPO_relaxed.owl FYPO:0001453 biolink:NamedThing resistance to ethanol An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethanol than normal. FYPO_relaxed.owl FYPO:0001499 biolink:NamedThing resistance to cytochalasin B An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cytochalasin B than normal. FYPO_relaxed.owl FYPO:0001516 biolink:NamedThing resistance to mercury An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of mercury ions than normal. FYPO_relaxed.owl FYPO:0001517 biolink:NamedThing resistance to aluminium An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of aluminium ions than normal. FYPO_relaxed.owl FYPO:0001518 biolink:NamedThing resistance to diethyl maleate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of diethyl maleate than normal. FYPO_relaxed.owl FYPO:0001524 biolink:NamedThing resistance to L-thialysine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of L-thialysine than normal. FYPO_relaxed.owl FYPO:0001557 biolink:NamedThing resistance to ethionine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethionine than normal. FYPO_relaxed.owl FYPO:0001583 biolink:NamedThing resistance to lithium An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of lithium ions than normal. FYPO_relaxed.owl FYPO:0001882 biolink:NamedThing resistance to cell wall-degrading enzymes An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of one or more enzymes that degrades cell wall polysaccharides than normal. FYPO_relaxed.owl FYPO:0001884 biolink:NamedThing resistance to Calcofluor White An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of Calcofluor White than normal. FYPO_relaxed.owl FYPO:0001941 biolink:NamedThing resistance to cerulenin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cerulenin than normal. FYPO_relaxed.owl FYPO:0001963 biolink:NamedThing resistance to papulacandin B An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of papulacandin B than normal. FYPO_relaxed.owl FYPO:0001964 biolink:NamedThing resistance to aculeacin A An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of aculeacin A than normal. FYPO_relaxed.owl FYPO:0001965 biolink:NamedThing resistance to papulacandin D An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of papulacandin D than normal. FYPO_relaxed.owl FYPO:0001986 biolink:NamedThing resistance to 5-fluorouracil An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 5-fluorouracil than normal. FYPO_relaxed.owl FYPO:0002162 biolink:NamedThing resistance to cilofungin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cilofungin than normal. FYPO_relaxed.owl FYPO:0002578 biolink:NamedThing resistance to hydroxyurea An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of hydroxyurea than normal. FYPO_relaxed.owl FYPO:0002588 biolink:NamedThing resistance to nickel An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of nickel ions than normal. FYPO_relaxed.owl FYPO:0002589 biolink:NamedThing resistance to zinc An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of zinc ions than normal. FYPO_relaxed.owl FYPO:0002634 biolink:NamedThing resistance to cobalt An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cobalt ions than normal. FYPO_relaxed.owl FYPO:0002693 biolink:NamedThing resistance to diamide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) than normal. FYPO_relaxed.owl FYPO:0002694 biolink:NamedThing resistance to hygromycin B An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of hygromycin B than normal. FYPO_relaxed.owl FYPO:0002706 biolink:NamedThing resistance to cordycepin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cordycepin than normal. FYPO_relaxed.owl FYPO:0002757 biolink:NamedThing resistance to quinidine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of quinidine than normal. FYPO_relaxed.owl FYPO:0002758 biolink:NamedThing resistance to 4-nitroquinoline N-oxide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 4-nitroquinoline N-oxide than normal. FYPO_relaxed.owl FYPO:0002766 biolink:NamedThing resistance to clotrimazole An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of clotrimazole than normal. FYPO_relaxed.owl FYPO:0002767 biolink:NamedThing resistance to terbinafine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of terbinafine than normal. FYPO_relaxed.owl FYPO:0002864 biolink:NamedThing resistance to 5-fluoroorotic acid An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 5-fluoroorotic acid than normal. FYPO_relaxed.owl FYPO:0003022 biolink:NamedThing resistance to nocodazole An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of nocodazole than normal. FYPO_relaxed.owl FYPO:0003113 biolink:NamedThing resistance to sodium nitroprusside An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of sodium nitroprusside than normal. FYPO_relaxed.owl FYPO:0003115 biolink:NamedThing resistance to L-methionine (R)-S-oxide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of L-methionine (R)-S-oxide than normal. FYPO_relaxed.owl FYPO:0003325 biolink:NamedThing resistance to methotrexate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of methotrexate than normal. FYPO_relaxed.owl FYPO:0003368 biolink:NamedThing resistance to sodium fluoride An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of sodium fluoride than normal. FYPO_relaxed.owl FYPO:0003383 biolink:NamedThing resistance to tert-butyl hydroperoxide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tert-butyl hydroperoxide (TBHP or t-BOOH) than normal. FYPO_relaxed.owl FYPO:0003396 biolink:NamedThing resistance to ricinoleic acid An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ricinoleic acid than normal. FYPO_relaxed.owl FYPO:0003406 biolink:NamedThing resistance to methylglyoxal An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of methylglyoxal than normal. FYPO_relaxed.owl FYPO:0003407 biolink:NamedThing resistance to glyoxal An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of glyoxal than normal. FYPO_relaxed.owl FYPO:0003492 biolink:NamedThing resistance to beta-glucanase An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of beta-glucanase, any enzyme that degrades cell wall polysaccharides by hydrolyzing beta-glucan linkages, than normal. FYPO_relaxed.owl FYPO:0003493 biolink:NamedThing resistance to hypothemycin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of hypothemycin than normal. FYPO_relaxed.owl FYPO:0003646 biolink:NamedThing resistance to pyrithiamine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of pyrithiamine than normal. FYPO_relaxed.owl FYPO:0003824 biolink:NamedThing resistance to caffeine and rapamycin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of caffeine and rapamycin than normal. FYPO_relaxed.owl FYPO:0003860 biolink:NamedThing resistance to miconazole An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of miconazole than normal. FYPO_relaxed.owl FYPO:0003895 biolink:NamedThing resistance to rotenone An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of rotenone than normal. FYPO_relaxed.owl FYPO:0003902 biolink:NamedThing resistance to etoposide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of etoposide than normal. FYPO_relaxed.owl FYPO:0004025 biolink:NamedThing resistance to carbendazim An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of the tubulin poison carbendazim (mecarzole; MBC) than normal. FYPO_relaxed.owl FYPO:0004135 biolink:NamedThing resistance to copper An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of copper ions than normal. FYPO_relaxed.owl FYPO:0004398 biolink:NamedThing resistance to phenylarsine oxide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of phenylarsine oxide than normal. FYPO_relaxed.owl FYPO:0004403 biolink:NamedThing resistance to JM216 An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of JM216 (also called satraplatin) than normal. FYPO_relaxed.owl FYPO:0004454 biolink:NamedThing resistance to calcium An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of calcium ions than normal. FYPO_relaxed.owl FYPO:0004513 biolink:NamedThing resistance to latrunculin A An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of latrunculin A than normal. FYPO_relaxed.owl FYPO:0004561 biolink:NamedThing resistance to BE49385A An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of BE49385A (a GPI synthesis inhibitor, also called YW3548) than normal. FYPO_relaxed.owl FYPO:0004751 biolink:NamedThing resistance to G418 An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of G418 than normal. FYPO_relaxed.owl FYPO:0004752 biolink:NamedThing resistance to phleomycin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of phleomycin than normal. FYPO_relaxed.owl FYPO:0004875 biolink:NamedThing resistance to allyl alcohol An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of allyl alcohol than normal. FYPO_relaxed.owl FYPO:0004945 biolink:NamedThing resistance to nigericin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of nigericin than normal. FYPO_relaxed.owl FYPO:0005150 biolink:NamedThing resistance to enfumafungin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of enfumafungin than normal. FYPO_relaxed.owl FYPO:0005151 biolink:NamedThing resistance to pneumocandin B0 An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of pneumocandin B0 than normal. FYPO_relaxed.owl FYPO:0005152 biolink:NamedThing resistance to caspofungin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of caspofungin than normal. FYPO_relaxed.owl FYPO:0005186 biolink:NamedThing resistance to hexavalent chromium An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of hexavalent chromium ions (Cr6+) than normal. FYPO_relaxed.owl FYPO:0005193 biolink:NamedThing resistance to torin1 An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of torin1 than normal. FYPO_relaxed.owl FYPO:0005248 biolink:NamedThing resistance to tellurite An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tellurite (TeO3(2-)) ions than normal. FYPO_relaxed.owl FYPO:0005249 biolink:NamedThing resistance to caesium An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of caesium ions than normal. FYPO_relaxed.owl FYPO:0005253 biolink:NamedThing resistance to tamoxifen An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tamoxifen than normal. FYPO_relaxed.owl FYPO:0005264 biolink:NamedThing resistance to dithiothreitol An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of dithiothreitol than normal. FYPO_relaxed.owl FYPO:0005265 biolink:NamedThing resistance to lead An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of lead ions than normal. FYPO_relaxed.owl FYPO:0005266 biolink:NamedThing resistance to sodium dodecyl sulfate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of sodium dodecyl sulfate (SDS) than normal. FYPO_relaxed.owl FYPO:0005645 biolink:NamedThing resistance to Cutin-1 An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of Cutin-1 (N-carbamoyl-2-(triphenyl-lambda-5-phosphanylidene)acetamide) than normal. FYPO_relaxed.owl FYPO:0005968 biolink:NamedThing resistance to sodium chloride An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of sodium chloride than normal. FYPO_relaxed.owl FYPO:0005969 biolink:NamedThing resistance to magnesium chloride An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of magnesium chloride than normal. FYPO_relaxed.owl FYPO:0006580 biolink:NamedThing resistance to amiodarone An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of amiodarone than normal. FYPO_relaxed.owl FYPO:0006735 biolink:NamedThing resistance to tschimganine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tschimganine than normal. FYPO_relaxed.owl FYPO:0006779 biolink:NamedThing resistance to spermidine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of spermidine than normal. FYPO_relaxed.owl FYPO:0006781 biolink:NamedThing resistance to Rbin-1 An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of Rbin-1 than normal. FYPO_relaxed.owl FYPO:0006932 biolink:NamedThing resistance to butylated hydroxyanisole An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of butylated hydroxyanisole than normal. FYPO_relaxed.owl FYPO:0006933 biolink:NamedThing resistance to butylated hydroxytoluene An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of butylated hydroxytoluene (dibutylhydroxytoluene; BHT) than normal. FYPO_relaxed.owl FYPO:0007033 biolink:NamedThing resistance to fluconazole An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of fluconazole than normal. FYPO_relaxed.owl FYPO:0007034 biolink:NamedThing resistance to phenylglyoxal An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of phenylglyoxal than normal. FYPO_relaxed.owl FYPO:0007359 biolink:NamedThing resistance to heavy water An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of heavy water (D2O) than normal. FYPO_relaxed.owl FYPO:0007372 biolink:NamedThing resistance to chlorpromazine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of chlorpromazine than normal. FYPO_relaxed.owl FYPO:0007521 biolink:NamedThing resistance to tacrolimus and magnesium chloride An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of tacrolimus and magnesium chloride than normal. FYPO_relaxed.owl FYPO:0007716 biolink:NamedThing resistance to tebuconazole An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tebuconazole than normal. FYPO_relaxed.owl FYPO:0007808 biolink:NamedThing resistance to valproic acid An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of valproic acid than normal. FYPO_relaxed.owl FYPO:0008215 biolink:NamedThing resistance to Rho GTPase inhibitor O1 An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of GTPase inhibitor O1 than normal. FYPO_relaxed.owl FYPO:0009030 biolink:NamedThing resistance to amitrole An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of amitrole than normal. FYPO_relaxed.owl FYPO:0009031 biolink:NamedThing resistance to bleomycin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of bleomycin than normal. FYPO_relaxed.owl FYPO:0009032 biolink:NamedThing resistance to bortezomib An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of bortezomib than normal. FYPO_relaxed.owl FYPO:0009033 biolink:NamedThing resistance to dihydrocoumarin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of dihydrocoumarin than normal. FYPO_relaxed.owl FYPO:0009034 biolink:NamedThing resistance to ethylenediaminetetraacetic acid An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethylenediaminetetraacetic acid than normal. FYPO_relaxed.owl FYPO:0009035 biolink:NamedThing resistance to formamide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of formamide than normal. FYPO_relaxed.owl FYPO:0009036 biolink:NamedThing resistance to benzamidine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of benzamidine than normal. FYPO_relaxed.owl FYPO:0009037 biolink:NamedThing resistance to phloxine B An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of phloxine B than normal. FYPO_relaxed.owl FYPO:0009038 biolink:NamedThing resistance to egtazic acid An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of egtazic acid than normal. FYPO_relaxed.owl FYPO:0009039 biolink:NamedThing resistance to potassium chloride An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of potassium chloride than normal. FYPO_relaxed.owl FYPO:0009040 biolink:NamedThing resistance to tea tree oil An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tea tree oil than normal. FYPO_relaxed.owl FYPO:0009041 biolink:NamedThing resistance to 2,2′-dipyridyl An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of 2,2′-dipyridyl than normal. FYPO_relaxed.owl FYPO:0009042 biolink:NamedThing resistance to sorbitol An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of sorbitol than normal. FYPO_relaxed.owl FYPO:0009043 biolink:NamedThing resistance to potassium chloride and sodium dodecyl sulfate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of potassium chloride and sodium dodecyl sulfate than normal. FYPO_relaxed.owl FYPO:0009044 biolink:NamedThing resistance to sodium chloride and methyl methanesulfonate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of sodium chloride and methyl methanesulfonate than normal. FYPO_relaxed.owl FYPO:0009045 biolink:NamedThing resistance to calcofluor and potassium chloride An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of calcofluor and potassium chloride than normal. FYPO_relaxed.owl FYPO:0009046 biolink:NamedThing resistance to phloxine B and hydrogen peroxide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of phloxine B and hydrogen peroxide than normal. FYPO_relaxed.owl FYPO:0009047 biolink:NamedThing resistance to dimethyl sulfoxide An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of dimethyl sulfoxide than normal. FYPO_relaxed.owl FYPO:0009048 biolink:NamedThing resistance to cysteine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of cysteine than normal. FYPO_relaxed.owl FYPO:0009049 biolink:NamedThing resistance to methionine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of methionine than normal. FYPO_relaxed.owl FYPO:0009050 biolink:NamedThing resistance to hydroxyurea and methyl methanesulfonate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of hydroxyurea and methyl methanesulfonate than normal. FYPO_relaxed.owl FYPO:0009055 biolink:NamedThing resistance to ethyl methanesulfonate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ethyl methanesulfonate than normal. FYPO_relaxed.owl FYPO:0009060 biolink:NamedThing resistance to wortmannin An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of wortmannin than normal. FYPO_relaxed.owl FYPO:0009065 biolink:NamedThing resistance to X-rays and rapamycin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased resistance to a combination of X-rays and ramapycin. FYPO_relaxed.owl FYPO:0009066 biolink:NamedThing resistance to amorolfine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of amorolfine than normal. FYPO_relaxed.owl FYPO:0009068 biolink:NamedThing resistance to ciclopirox olamine An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of ciclopirox olamine than normal. FYPO_relaxed.owl FYPO:0009070 biolink:NamedThing resistance to itraconazole An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of itraconazole than normal. FYPO_relaxed.owl FYPO:0009079 biolink:NamedThing resistance to calcofluor and sodium dodecyl sulfate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of calcofluor and sodium dodecyl sulfate than normal. FYPO_relaxed.owl FYPO:0009081 biolink:NamedThing resistance to potassium chloride and methyl methanesulfonate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of potassium chloride and methyl methanesulfonate than normal. FYPO_relaxed.owl FYPO:0009083 biolink:NamedThing resistance to lithium chloride and methyl methanesulfonate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of lithium chloride and methyl methanesulfonate than normal. FYPO_relaxed.owl FYPO:0009085 biolink:NamedThing resistance to lithium chloride and sodium dodecyl sulfate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of lithium chloride and sodium dodecyl sulfate than normal. FYPO_relaxed.owl FYPO:0009087 biolink:NamedThing resistance to magnesium chloride and sodium dodecyl sulfate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of magnesium chloride and sodium dodecyl sulfate than normal. FYPO_relaxed.owl FYPO:0009089 biolink:NamedThing resistance to sodium chloride and sodium dodecyl sulfate An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of higher concentrations of sodium chloride and sodium dodecyl sulfate than normal. FYPO_relaxed.owl FYPO:0000078 biolink:NamedThing abnormal cellular respiration A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular respiration is abnormal. FYPO_relaxed.owl FYPO:0000122 biolink:NamedThing abnormal telomere maintenance during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere maintenance, i.e. any process that contributes to the maintenance of proper telomeric length and structure, is abnormal. FYPO_relaxed.owl FYPO:0000203 biolink:NamedThing abnormal ergosterol biosynthetic process A metabolism phenotype observed in the vegetative growth phase of the life cycle in which ergosterol biosynthesis is abnormal. FYPO_relaxed.owl FYPO:0000204 biolink:NamedThing abnormal mRNA export from nucleus A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of mRNA from the nucleus is abnormal. FYPO_relaxed.owl FYPO:0000328 biolink:NamedThing abnormal protein metabolic process during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle that affects protein metabolism in the cell. FYPO_relaxed.owl FYPO:0000370 biolink:NamedThing abnormal RNA modification A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA modification is abnormal. All RNA modification may be abnormal, or one or more specific RNA modifications may be selectively affected. FYPO_relaxed.owl FYPO:0000430 biolink:NamedThing abnormal fermentation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which fermentation is abnormal. FYPO_relaxed.owl FYPO:0000481 biolink:NamedThing abnormal mitotic recombination A cellular process phenotype in which mitotic recombination is abnormal. FYPO_relaxed.owl FYPO:0001553 biolink:NamedThing abnormal RNA processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA processing is abnormal. RNA processing is the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. FYPO_relaxed.owl FYPO:0001735 biolink:NamedThing abnormal iron-sulfur cluster transfer A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein is abnormal. FYPO_relaxed.owl FYPO:0001797 biolink:NamedThing abnormal translation A metabolism phenotype observed in the vegetative growth phase of the life cycle in which translation is abnormal. Translation is the synthesis of a protein using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. FYPO_relaxed.owl FYPO:0002136 biolink:NamedThing abnormal RNA catabolic process during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an RNA catabolic process is abnormal. FYPO_relaxed.owl FYPO:0002614 biolink:NamedThing abnormal protein localization to pre-autophagosomal structure A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the pre-autophagosomal structure is abnormal. FYPO_relaxed.owl FYPO:0002631 biolink:NamedThing abnormal dTTP biosynthetic process A metabolism phenotype observed in the vegetative growth phase of the life cycle in which dTTP biosynthesis is abnormal. FYPO_relaxed.owl FYPO:0003088 biolink:NamedThing abnormal replication fork arrest A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest is abnormal. FYPO_relaxed.owl FYPO:0003586 biolink:NamedThing abnormal replication fork processing A cell phenotype observed in the vegetative growth phase of the life cycle in which replication fork processing is abnormal. Replication fork processing is process in which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired and replication is restarted. FYPO_relaxed.owl FYPO:0003953 biolink:NamedThing abnormal triglyceride biosynthetic process A metabolism phenotype observed in the vegetative growth phase of the life cycle in which triglyceride biosynthesis is abnormal. FYPO_relaxed.owl FYPO:0004064 biolink:NamedThing abnormal transcription during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription of RNA from one or more DNA templates is abnormal. FYPO_relaxed.owl FYPO:0004269 biolink:NamedThing abnormal cell septum edging catabolic process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dissolution of the cell septum edging material is abnormal; may result in the formation of chains of attached cells. FYPO_relaxed.owl FYPO:0005355 biolink:NamedThing abnormal site-specific DNA replication termination at RTS1 barrier A cellular process phenotype observed in the vegetative growth phase of the life cycle in which site-specific DNA replication termination at RTS1 barrier in the mating type region is abnormal. FYPO_relaxed.owl FYPO:0005956 biolink:NamedThing abnormal protein dephosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dephosphorylation of one or more specific proteins is abnormal. FYPO_relaxed.owl FYPO:0007445 biolink:NamedThing abnormal reticulophagy during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which autophagic degradation of the endoplasmic reticulum is abnormal. FYPO_relaxed.owl FYPO:0000079 biolink:NamedThing sensitive to caspofungin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to caspofungin. Cells stop growing (and may die) at a concentration of caspofungin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007947 biolink:NamedThing sensitive to echinocandin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to echinocandin. Cells stop growing (and may die) at a concentration of echinocandin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001189 biolink:NamedThing sensitive to cilofungin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cilofungin. Cells stop growing (and may die) at a concentration of cilofungin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002641 biolink:NamedThing sensitive to micafungin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to micafungin. Cells stop growing (and may die) at a concentration of micafungin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000080 biolink:NamedThing decreased cell population growth at low temperature A vegetative cell population growth phenotype in which cell growth is decreased relative to normal at a low temperature. FYPO_relaxed.owl FYPO:0001355 biolink:NamedThing decreased vegetative cell population growth A cell population phenotype in which the growth of a population of cells is decreased relative to normal in the vegetative growth phase of the life cycle. Decreased growth may reflect a reduced growth rate (i.e. slower growth), growth that occurs to a lesser extent than normal, or both. FYPO_relaxed.owl FYPO:0000082 biolink:NamedThing decreased cell population growth at high temperature A cell population phenotype in which the growth of a population of cells is decreased relative to normal in the vegetative growth phase of the life cycle at high temperatures. FYPO_relaxed.owl FYPO:0000249 biolink:NamedThing decreased cell population growth on ammonia nitrogen source A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing ammonia as the nitrogen source. FYPO_relaxed.owl FYPO:0000250 biolink:NamedThing decreased cell population growth on proline nitrogen source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-proline as the nitrogen source. FYPO_relaxed.owl FYPO:0000251 biolink:NamedThing decreased cell population growth on galactose carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing galactose as the carbon source. FYPO_relaxed.owl FYPO:0000442 biolink:NamedThing decreased cell population growth on glycerol/ethanol carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing glycerol and ethanol as the carbon sources. FYPO_relaxed.owl FYPO:0000684 biolink:NamedThing decreased cell population growth on glycerol carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing glycerol as the carbon source. FYPO_relaxed.owl FYPO:0001162 biolink:NamedThing decreased cell population growth on raffinose carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal under aerobic conditions and in a medium containing raffinose as the carbon source. FYPO_relaxed.owl FYPO:0001176 biolink:NamedThing decreased cell population growth on sucrose carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing sucrose as the carbon source. FYPO_relaxed.owl FYPO:0001177 biolink:NamedThing decreased cell population growth on trehalose carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing trehalose as the carbon source. FYPO_relaxed.owl FYPO:0001407 biolink:NamedThing decreased cell population growth on glucose carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing glucose as the carbon source. FYPO_relaxed.owl FYPO:0001575 biolink:NamedThing abolished vegetative cell population growth A cellular process phenotype in which vegetative cell population growth does not occur, although cells remain viable. FYPO_relaxed.owl FYPO:0001830 biolink:NamedThing decreased cell population growth on gluconate carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing gluconate as the carbon source. FYPO_relaxed.owl FYPO:0002924 biolink:NamedThing decreased cell population growth on maltose carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing maltose as the carbon source. FYPO_relaxed.owl FYPO:0003238 biolink:NamedThing decreased anaerobic cell population growth A vegetative cell population growth phenotype in which cell growth is decreased relative to normal under anaerobic conditions. FYPO_relaxed.owl FYPO:0003271 biolink:NamedThing decreased cell population growth on methionine sulfur source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-methionine as the sole sulfur source. FYPO_relaxed.owl FYPO:0003743 biolink:NamedThing decreased cell population growth during glucose starvation A cell growth phenotype in which cell population growth is decreased relative to normal under conditions of glucose starvation. FYPO_relaxed.owl FYPO:0003805 biolink:NamedThing decreased cell population growth on non-fermentable carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing one or more non-fermentable substance(s) as the only carbon source(s). FYPO_relaxed.owl FYPO:0004968 biolink:NamedThing decreased vegetative cell population growth during phosphate starvation A cell growth phenotype in which vegetative cell population growth is decreased relative to normal under conditions of phosphate starvation. FYPO_relaxed.owl FYPO:0005242 biolink:NamedThing decreased cell population growth on glutamine nitrogen source A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing glutamine as the nitrogen source. FYPO_relaxed.owl FYPO:0005244 biolink:NamedThing decreased cell population growth on arabinose carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing arabinose as the carbon source. FYPO_relaxed.owl FYPO:0005246 biolink:NamedThing decreased cell population growth on melibiose carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing melibiose as the carbon source. FYPO_relaxed.owl FYPO:0005393 biolink:NamedThing progressively decreasing vegetative cell population growth rate A cell population phenotype in which vegetative cell population growth is slower than normal, and the population growth rate decreases over successive generations. FYPO_relaxed.owl FYPO:0005394 biolink:NamedThing progressively decreasing vegetative cell population growth rate followed by return to normal growth rate A cell population phenotype in which vegetative cell population growth is slower than normal for several generations, with the population growth rate decreasing over successive generations, after which the population resumes growing at a normal or near-normal rate. FYPO_relaxed.owl FYPO:0007562 biolink:NamedThing decreased cell population growth on serine nitrogen source A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing serine as the nitrogen source. FYPO_relaxed.owl FYPO:0007726 biolink:NamedThing decreased cell population growth on phenylalanine nitrogen source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-phenylalanine as the nitrogen source. FYPO_relaxed.owl FYPO:0008020 biolink:NamedThing decreased cell population growth on leucine nitrogen source A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing leucine as the nitrogen source. FYPO_relaxed.owl FYPO:0008021 biolink:NamedThing decreased cell population growth on alanine nitrogen source A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing alanine as the nitrogen source. FYPO_relaxed.owl FYPO:0008081 biolink:NamedThing decreased vegetative cell population growth when co-cultured with wild-type cells A cell population phenotype in which the growth of a population of cells is decreased relative to normal in the vegetative growth phase of the life cycle when the population is co-cultured with wild-type cells. Decreased growth may reflect a reduced growth rate (i.e. slower growth), growth that occurs to a lesser extent than normal, or both. FYPO_relaxed.owl FYPO:0008128 biolink:NamedThing decreased vegetative cell population growth on low glucose A vegetative cell population phenotype in which cell growth is decreased relative to normal in a medium containing low glucose. This term refers to situations where glucose is below 0.2%. FYPO_relaxed.owl FYPO:0009009 biolink:NamedThing decreased cell population growth on arginine nitrogen source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing arginine as the nitrogen source. FYPO_relaxed.owl FYPO:0009021 biolink:NamedThing decreased cell population growth on cysteine nitrogen source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-cysteine as the nitrogen source. FYPO_relaxed.owl FYPO:0009022 biolink:NamedThing decreased cell population growth on isoleucine nitrogen source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-isoleucine as the nitrogen source. FYPO_relaxed.owl FYPO:0009023 biolink:NamedThing decreased cell population growth on methionine nitrogen source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-methionine as the nitrogen source. FYPO_relaxed.owl FYPO:0009053 biolink:NamedThing decreased cell population growth on glutamate nitrogen source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing L-glutamate as the nitrogen source. FYPO_relaxed.owl FYPO:0009073 biolink:NamedThing decreased cell population growth on lysine nitrogen source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing lysine as the nitrogen source. FYPO_relaxed.owl FYPO:0009075 biolink:NamedThing decreased cell population growth on fructose carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing fructose as the carbon source. FYPO_relaxed.owl FYPO:0009078 biolink:NamedThing decreased cell population growth on ethanol carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing ethanol as the carbon source. FYPO_relaxed.owl FYPO:0009091 biolink:NamedThing decreased cell population growth on lysine and proline nitrogen source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing lysine and proline as nitrogen sources. FYPO_relaxed.owl FYPO:0009092 biolink:NamedThing decreased cell population growth on lysine and serine nitrogen source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing lysine and serine as nitrogen sources. FYPO_relaxed.owl FYPO:0009097 biolink:NamedThing decreased cell population growth on xylose carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing xylose as the carbon source. FYPO_relaxed.owl FYPO:0009099 biolink:NamedThing decreased cell population growth on mannitol carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing mannitol as the carbon source. FYPO_relaxed.owl FYPO:0009100 biolink:NamedThing decreased cell population growth on glycerol and galactose carbon source A vegetative cell population growth phenotype in which cell growth is decreased relative to normal in a medium containing glycerol and galactose carbon sources. FYPO_relaxed.owl FYPO:0009109 biolink:NamedThing decreased vegetative cell population growth after short incubation in hydroxyurea A cell growth phenotype in which cell population growth is decreased relative to normal after short incubation in hydroxyurea. FYPO_relaxed.owl FYPO:0000081 biolink:NamedThing sensitive to high osmolarity A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to conditions of high osmolarity. FYPO_relaxed.owl FYPO:0000270 biolink:NamedThing sensitive to osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to osmotic stress. FYPO_relaxed.owl FYPO:0000271 biolink:NamedThing sensitive to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a salt stress. FYPO_relaxed.owl FYPO:0002077 biolink:NamedThing sensitive to low osmolarity A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to conditions of low osmolarity. FYPO_relaxed.owl FYPO:0002811 biolink:NamedThing sensitive to non-ionic osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a non-ionic osmotic stress. FYPO_relaxed.owl FYPO:0000083 biolink:NamedThing sensitive to enfumafungin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to enfumafungin. Cells stop growing (and may die) at a concentration of enfumafungin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000127 biolink:NamedThing increased sensitivity to chemical during vegetative growth A phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased resistance to a chemical stimulus. Resistance to a chemical is measured by determining the maximum concentration of the chemical at which a population of cells grow and divide. Typically, cells are deemed sensitive to a chemical if they stop growing (and may die) at a concentration of the chemical that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000084 biolink:NamedThing sensitive to 6-azauracil A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 6-azauracil. Cells stop growing (and may die) at a concentration of 6-azauracil that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000085 biolink:NamedThing sensitive to camptothecin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to camptothecin. Cells stop growing (and may die) at a concentration of camptothecin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000086 biolink:NamedThing sensitive to tacrolimus A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tacrolimus. Cells stop growing (and may die) at a concentration of tacrolimus that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000087 biolink:NamedThing sensitive to hydrogen peroxide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hydrogen peroxide. Cells stop growing (and may die) at a concentration of hydrogen peroxide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000088 biolink:NamedThing sensitive to hydroxyurea A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hydroxyurea. Cells stop growing (and may die) at a concentration of hydroxyurea that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000089 biolink:NamedThing sensitive to methyl methanesulfonate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to methyl methanesulfonate. Cells stop growing (and may die) at a concentration of methyl methanesulfonate that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000090 biolink:NamedThing sensitive to N-ethylmaleimide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to N-ethylmaleimide. Cells stop growing (and may die) at a concentration of N-ethylmaleimide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000091 biolink:NamedThing sensitive to thiabendazole A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to thiabendazole. Cells stop growing (and may die) at a concentration of thiabendazole that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000092 biolink:NamedThing sensitive to amiodarone A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to amiodarone. Cells stop growing (and may die) at a concentration of amiodarone that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000093 biolink:NamedThing sensitive to arsenic A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to an arsenic-containing substance. Cells stop growing (and may die) at a concentration of arsenic that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000094 biolink:NamedThing sensitive to benomyl A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to benomyl. Cells stop growing (and may die) at a concentration of benomyl that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000095 biolink:NamedThing sensitive to bleomycin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bleomycin. Cells stop growing (and may die) at a concentration of bleomycin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000096 biolink:NamedThing sensitive to cadmium A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cadmium. Cells stop growing (and may die) at a concentration of cadmium ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000097 biolink:NamedThing sensitive to caffeine during vegetative growth A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to caffeine. Cells stop growing (and may die) at a concentration of caffeine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000098 biolink:NamedThing sensitive to calcium A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to calcium. Cells stop growing (and may die) at a concentration of calcium ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000099 biolink:NamedThing sensitive to canavanine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to canavanine. Cells stop growing (and may die) at a concentration of canavanine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000100 biolink:NamedThing sensitive to chloramphenicol A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to chloramphenicol. Cells stop growing (and may die) at a concentration of chloramphenicol that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000101 biolink:NamedThing sensitive to chlorpropham A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to chlorpropham. Cells stop growing (and may die) at a concentration of chlorpropham that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000102 biolink:NamedThing sensitive to cisplatin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cisplatin. Cells stop growing (and may die) at a concentration of cisplatin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000103 biolink:NamedThing sensitive to copper A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to copper ions. Cells stop growing (and may die) at a concentration of copper ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000104 biolink:NamedThing sensitive to cycloheximide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cycloheximide. Cells stop growing (and may die) at a concentration of cycloheximide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000105 biolink:NamedThing sensitive to cyclosporin A A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cyclosporin A. Cells stop growing (and may die) at a concentration of cyclosporin A that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000106 biolink:NamedThing sensitive to hygromycin B A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hygromycin B. Cells stop growing (and may die) at a concentration of hygromycin B that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000107 biolink:NamedThing sensitive to latrunculin A A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to latrunculin A. Cells stop growing (and may die) at a concentration of latrunculin A that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000108 biolink:NamedThing sensitive to menadione A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to menadione. Cells stop growing (and may die) at a concentration of menadione that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000109 biolink:NamedThing sensitive to papulacandin B A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to papulacandin B. Cells stop growing (and may die) at a concentration of papulacandin B that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000110 biolink:NamedThing sensitive to pravastatin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to pravastatin. Cells stop growing (and may die) at a concentration of pravastatin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000111 biolink:NamedThing sensitive to rapamycin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to rapamycin. Cells stop growing (and may die) at a concentration of rapamycin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000112 biolink:NamedThing sensitive to sorbitol A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sorbitol. Cells stop growing (and may die) at a concentration of sorbitol that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000113 biolink:NamedThing sensitive to staurosporine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to staurosporine. Cells stop growing (and may die) at a concentration of staurosporine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000115 biolink:NamedThing sensitive to valproic acid A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to valproic acid. Cells stop growing (and may die) at a concentration of valproic acid that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000116 biolink:NamedThing sensitive to zinc A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to zinc ions. Cells stop growing (and may die) at a concentration of zinc ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000266 biolink:NamedThing sensitive to DNA damaging agents A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a genotoxin, any chemical compound that can act to induce direct or indirect DNA damage. Cells stop growing (and may die) at a concentration of a DNA damaging agent that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000269 biolink:NamedThing sensitive to microtubule depolymerizing drugs A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a microtubule-destabilizing substance. Cells stop growing (and may die) at a concentration of a microtubule-depolymerizing drug that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000440 biolink:NamedThing sensitive to antimycin A A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to antimycin A. Cells stop growing (and may die) at a concentration of antimycin A that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000633 biolink:NamedThing sensitive to G418 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to G418. Cells stop growing (and may die) at a concentration of G418 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000714 biolink:NamedThing sensitive to leptomycin B A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to leptomycin B. Cells stop growing (and may die) at a concentration of leptomycin B that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000715 biolink:NamedThing sensitive to K-252a A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to K-252a. Cells stop growing (and may die) at a concentration of K-252a that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000716 biolink:NamedThing sensitive to valinomycin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to valinomycin. Cells stop growing (and may die) at a concentration of valinomycin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000717 biolink:NamedThing sensitive to actinomycin D A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to actinomycin D. Cells stop growing (and may die) at a concentration of actinomycin D that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000748 biolink:NamedThing sensitive to mercury A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mercury ions. Cells stop growing (and may die) at a concentration of mercury ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000749 biolink:NamedThing sensitive to selenite ion A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to selenite ((SeO3)2-) ions. Cells stop growing (and may die) at a concentration of selenite ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000750 biolink:NamedThing sensitive to silver ions A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to silver ions. Cells stop growing (and may die) at a concentration of silver ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000751 biolink:NamedThing sensitive to nickel A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nickel ions. Cells stop growing (and may die) at a concentration of nickel ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000756 biolink:NamedThing sensitive to bafilomycin A1 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bafilomycin A1. Cells stop growing (and may die) at a concentration of bafilomycin A1 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000757 biolink:NamedThing sensitive to nigericin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nigericin. Cells stop growing (and may die) at a concentration of nigericin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000758 biolink:NamedThing sensitive to bismuth A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bismuth ions. Cells stop growing (and may die) at a concentration of bismuth that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000759 biolink:NamedThing sensitive to lead A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to lead ions. Cells stop growing (and may die) at a concentration of lead ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000785 biolink:NamedThing sensitive to formamide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to formamide. Cells stop growing (and may die) at a concentration of formamide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000789 biolink:NamedThing sensitive to 1-NA-PP1 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 1-NA-PP1. Cells stop growing (and may die) at a concentration of 1-NA-PP1 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000797 biolink:NamedThing sensitive to tert-butyl hydroperoxide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tert-butyl hydroperoxide (TBHP or t-BOOH). Cells stop growing (and may die) at a concentration of tert-butyl hydroperoxide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000798 biolink:NamedThing sensitive to anisomycin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to anisomycin. Cells stop growing (and may die) at a concentration of anisomycin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000799 biolink:NamedThing sensitive to diamide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide, also known as diamide. Cells stop growing (and may die) at a concentration of diamide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000841 biolink:NamedThing sensitive to sodium dodecyl sulfate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium dodecyl sulfate (SDS). Cells stop growing (and may die) at a concentration of SDS that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000842 biolink:NamedThing sensitive to ethanol during vegetative growth A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ethanol. Cells stop growing (and may die) at a concentration of ethanol that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000843 biolink:NamedThing sensitive to dithiothreitol A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 1,4-dithiothreitol (DTT). Cells stop growing (and may die) at a concentration of dithiothreitol that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000844 biolink:NamedThing sensitive to mercaptoethanol A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mercaptoethanol. Cells stop growing (and may die) at a concentration of mercaptoethanol that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000970 biolink:NamedThing sensitive to mitomycin C A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mitomycin C. Cells stop growing (and may die) at a concentration of mitomycin C that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001097 biolink:NamedThing sensitive to amitrole A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to amitrole. Cells stop growing (and may die) at a concentration of amitrole that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001098 biolink:NamedThing sensitive to 4-nitroquinoline N-oxide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 4-nitroquinoline N-oxide. Cells stop growing (and may die) at a concentration of 4-nitroquinoline N-oxide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001150 biolink:NamedThing sensitive to methylamine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to methylamine. Cells stop growing (and may die) at a concentration of methylamine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001188 biolink:NamedThing sensitive to Calcofluor White A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Calcofluor White. Cells stop growing (and may die) at a concentration of Calcofluor White that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001190 biolink:NamedThing sensitive to cell wall-degrading enzymes A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to one or more enzymes that degrades cell wall polysaccharides. Cells stop growing (and may die) at a concentration of such enzymes that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001207 biolink:NamedThing sensitive to raffinose A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to raffinose. Cells stop growing (and may die) at a concentration of raffinose that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001214 biolink:NamedThing sensitive to potassium chloride A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to potassium chloride. Cells stop growing (and may die) at a concentration of potassium chloride that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001245 biolink:NamedThing sensitive to cobalt A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cobalt ions. FYPO_relaxed.owl FYPO:0001414 biolink:NamedThing sensitive to sulfide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sulfide (S2-). Cells stop growing (and may die) at a concentration of sulfide ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001457 biolink:NamedThing sensitive to tunicamycin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tunicamycin. Cells stop growing (and may die) at a concentration of tunicamycin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001488 biolink:NamedThing sensitive to protamine sulfate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to protamine sulfate. A protamine is any of a group of simple proteins that yield basic amino acids on hydrolysis, and forms a complex with heparin. Cells stop growing (and may die) at a concentration of protamine sulfate that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001498 biolink:NamedThing sensitive to cytochalasin B A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cytochalasin B. Cells stop growing (and may die) at a concentration of cytochalasin B that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001501 biolink:NamedThing sensitive to brefeldin A A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to brefeldin A. Cells stop growing (and may die) at a concentration of brefeldin A that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001525 biolink:NamedThing sensitive to L-thialysine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to L-thialysine. Cells stop growing (and may die) at a concentration of L-thialysine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001692 biolink:NamedThing sensitive to purvalanol A A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to purvalanol A. Cells stop growing (and may die) at a concentration of purvalanol A that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001693 biolink:NamedThing sensitive to reversine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to reversine. Cells stop growing (and may die) at a concentration of reversine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001694 biolink:NamedThing sensitive to hesperadin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hesperadin. Cells stop growing (and may die) at a concentration of hesperadin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001695 biolink:NamedThing sensitive to protease inhibitor A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a protease inhibitor. Cells stop growing (and may die) at a concentration of a protease inhibitor that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001696 biolink:NamedThing sensitive to protein kinase inhibitor A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a protein kinase inhibitor. Cells stop growing (and may die) at a concentration of a protein kinase inhibitor that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001697 biolink:NamedThing sensitive to topoisomerase inhibitor A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a topoisomerase inhibitor. Cells stop growing (and may die) at a concentration of a topoisomerase inhibitor that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001698 biolink:NamedThing sensitive to capsazepine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to capsazepine. Cells stop growing (and may die) at a concentration of capsazepine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001699 biolink:NamedThing sensitive to PPT A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 4,4',4''-(4-propylpyrazole-1,3,5-triyl)trisphenol (PPT). Cells stop growing (and may die) at a concentration of PPT that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001700 biolink:NamedThing sensitive to GW 7647 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to the receptor agonist GW 7647. Cells stop growing (and may die) at a concentration of GW 7647 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001701 biolink:NamedThing sensitive to bortezomib A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bortezomib. Cells stop growing (and may die) at a concentration of bortezomib that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001702 biolink:NamedThing sensitive to nocodazole A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nocodazole. Cells stop growing (and may die) at a concentration of nocodazole that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001719 biolink:NamedThing sensitive to lithium A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to lithium ions. Cells stop growing (and may die) at a concentration of lithium ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001813 biolink:NamedThing sensitive to N-methyl-N'-nitro-N-nitrosoguanidine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to N-methyl-N'-nitro-N-nitrosoguanidine. Cells stop growing (and may die) at a concentration of N-methyl-N'-nitro-N-nitrosoguanidine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001823 biolink:NamedThing sensitive to chlorpromazine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to chlorpromazine. Cells stop growing (and may die) at a concentration of chlorpromazine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001824 biolink:NamedThing sensitive to trifluoperazine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to trifluoperazine. Cells stop growing (and may die) at a concentration of trifluoperazine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001843 biolink:NamedThing sensitive to rhizoxin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to rhizoxin. Cells stop growing (and may die) at a concentration of rhizoxin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001844 biolink:NamedThing sensitive to ansamitocin P-3 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ansamitocin P-3. Cells stop growing (and may die) at a concentration of ansamitocin P-3 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001966 biolink:NamedThing sensitive to aculeacin A A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to aculeacin A. Cells stop growing (and may die) at a concentration of aculeacin A that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002016 biolink:NamedThing sensitive to oxygen A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to oxygen. Cells stop growing (and may die) at a level of oxygen that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002167 biolink:NamedThing sensitive to ethyl methanesulfonate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ethyl methanesulfonate. Cells stop growing (and may die) at a concentration of ethyl methanesulfonate that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002237 biolink:NamedThing sensitive to cerulenin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cerulenin. Cells stop growing (and may die) at a concentration of cerulenin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002328 biolink:NamedThing sensitive to terbinafine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to terbinafine. Cells stop growing (and may die) at a concentration of terbinafine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002344 biolink:NamedThing sensitive to phleomycin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity phleomycin. Cells stop growing (and may die) at a concentration of phleomycin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002345 biolink:NamedThing sensitive to oxaliplatin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to oxaliplatin. Cells stop growing (and may die) at a concentration of oxaliplatin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002526 biolink:NamedThing sensitive to latrunculin B A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to latrunculin B. Cells stop growing (and may die) at a concentration of latrunculin B that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002546 biolink:NamedThing sensitive to trichostatin A A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to trichostatin A. Cells stop growing (and may die) at a concentration of trichostatin A that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002547 biolink:NamedThing sensitive to nicotinamide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nicotinamide. Cells stop growing (and may die) at a concentration of nicotinamide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002617 biolink:NamedThing sensitive to sodium butyrate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium butyrate. Cells stop growing (and may die) at a concentration of sodium butyrate that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002640 biolink:NamedThing sensitive to clotrimazole A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to clotrimazole. Cells stop growing (and may die) at a concentration of clotrimazole that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002642 biolink:NamedThing sensitive to amphotericin B A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to amphotericin B. Cells stop growing (and may die) at a concentration of amphotericin B that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002689 biolink:NamedThing sensitive to cumene hydroperoxide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cumene hydroperoxide. Cells stop growing (and may die) at a concentration of cumene hydroperoxide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002692 biolink:NamedThing sensitive to paraquat A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to paraquat. Cells stop growing (and may die) at a concentration of paraquat that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002701 biolink:NamedThing sensitive to torin1 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to torin1. Cells stop growing (and may die) at a concentration of torin1 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002705 biolink:NamedThing sensitive to methionine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to methionine. Cells stop growing (and may die) at a concentration of methionine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002865 biolink:NamedThing sensitive to polypeptone A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to polypeptone. Cells stop growing (and may die) at a concentration of polypeptone that allows wild type cells to grow. Polypeptone is a mixture of peptones made up of equal parts of pancreatic digest of casein and peptic digest of animal used in media. FYPO_relaxed.owl FYPO:0002866 biolink:NamedThing sensitive to tryptone A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tryptone. Cells stop growing (and may die) at a concentration of tryptone that allows wild type cells to grow. Tryptone is a mixture of peptides produced by digestion of casein with trypsin. FYPO_relaxed.owl FYPO:0002988 biolink:NamedThing sensitive to ammonium A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ammonium. Cells stop growing (and may die) at a concentration of ammonium that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003021 biolink:NamedThing sensitive to EPC A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ethyl N-phenylcarbamate (EPC). Cells stop growing (and may die) at a concentration of EPC that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003110 biolink:NamedThing sensitive to caffeine and rapamycin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of caffeine and rapamycin. Cells stop growing (and may die) at concentrations of caffeine and rapamycin that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0003116 biolink:NamedThing sensitive to plumbagin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to plumbagin. Cells stop growing (and may die) at a concentration of plumbagin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003222 biolink:NamedThing sensitive to zearalenone A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to zearalenone. Cells stop growing (and may die) at a concentration of zearalenone that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003275 biolink:NamedThing sensitive to nitrite A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nitrite ions. Cells stop growing (and may die) at a concentration of nitrite ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003276 biolink:NamedThing sensitive to sodium hypochlorite A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium hypochlorite. Cells stop growing (and may die) at a concentration of sodium hypochlorite that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003357 biolink:NamedThing sensitive to filipin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to filipin. Cells stop growing (and may die) at a concentration of filipin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003358 biolink:NamedThing sensitive to miconazole A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to miconazole. Cells stop growing (and may die) at a concentration of miconazole that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003359 biolink:NamedThing sensitive to myriocin during vegetative growth A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to myriocin. Cells stop growing (and may die) at a concentration of myriocin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003369 biolink:NamedThing sensitive to sodium fluoride A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium fluoride. Cells stop growing (and may die) at a concentration of sodium fluoride that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003384 biolink:NamedThing sensitive to chromium A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to chromium ions. Cells stop growing (and may die) at a concentration of chromium ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003408 biolink:NamedThing sensitive to methylglyoxal A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to methylglyoxal. Cells stop growing (and may die) at a concentration of methylglyoxal that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003494 biolink:NamedThing sensitive to L-azetidine-2-carboxylic acid A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to L-azetidine-2-carboxylic acid. Cells stop growing (and may die) at a concentration of L-azetidine-2-carboxylic acid that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003559 biolink:NamedThing sensitive to doxorubicin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to doxorubicin. Cells stop growing (and may die) at a concentration of doxorubicin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003616 biolink:NamedThing sensitive to fluphenazine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to fluphenazine. Cells stop growing (and may die) at a concentration of fluphenazine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003617 biolink:NamedThing sensitive to cytochalasin D A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cytochalasin D. Cells stop growing (and may die) at a concentration of cytochalasin D that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003656 biolink:NamedThing sensitive to vanadate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to vanadate ions (VO4(3-)). Cells stop growing (and may die) at a concentration of vanadate ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003670 biolink:NamedThing sensitive to mycophenolic acid A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mycophenolic acid. Cells stop growing (and may die) at a concentration of mycophenolic acid that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003679 biolink:NamedThing sensitive to epirubicin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to epirubicin. Cells stop growing (and may die) at a concentration of epirubicin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003705 biolink:NamedThing sensitive to trapoxin A A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to trapoxin A. Cells stop growing (and may die) at a concentration of trapoxin A that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003718 biolink:NamedThing sensitive to tributyltin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tributyltin. Cells stop growing (and may die) at a concentration of tributyltin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003840 biolink:NamedThing sensitive to carbendazim A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to carbendazim (mecarzole; MBC). Cells stop growing (and may die) at a concentration of carbendazim that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003848 biolink:NamedThing sensitive to hydrazinocurcumin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hydrazinocurcumin. Cells stop growing (and may die) at a concentration of hydrazinocurcumin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003853 biolink:NamedThing sensitive to fluconazole A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to fluconazole. Cells stop growing (and may die) at a concentration of fluconazole that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003854 biolink:NamedThing sensitive to oligomycin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to an oligomycin antibiotic. Cells stop growing (and may die) at a concentration of oligomycin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003855 biolink:NamedThing sensitive to MTT A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide). Cells stop growing (and may die) at a concentration of MTT that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003856 biolink:NamedThing sensitive to FR901464 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to FR901464. Cells stop growing (and may die) at a concentration of FR901464 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003857 biolink:NamedThing sensitive to mevastatin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mevastatin. Cells stop growing (and may die) at a concentration of mevastatin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003858 biolink:NamedThing sensitive to etoposide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to etoposide. Cells stop growing (and may die) at a concentration of etoposide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003859 biolink:NamedThing sensitive to wortmannin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to wortmannin. Cells stop growing (and may die) at a concentration of wortmannin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003878 biolink:NamedThing sensitive to monensin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to monensin. Cells stop growing (and may die) at a concentration of monensin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003894 biolink:NamedThing sensitive to rotenone A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to rotenone. Cells stop growing (and may die) at a concentration of rotenone that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003907 biolink:NamedThing sensitive to okadaic acid A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to okadaic acid. Cells stop growing (and may die) at a concentration of okadaic acid that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004184 biolink:NamedThing sensitive to papuamide B during vegetative growth A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to papuamide B. Cells stop growing (and may die) at a concentration of papuamide B that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004325 biolink:NamedThing sensitive to 5-fluorouracil A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 5-fluorouracil. Cells stop growing (and may die) at a concentration of 5-fluorouracil that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004375 biolink:NamedThing sensitive to Ku-0063794 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Ku-0063794. Cells stop growing (and may die) at a concentration of Ku-0063794 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004402 biolink:NamedThing sensitive to JM216 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to JM216 (also called satraplatin). Cells stop growing (and may die) at a concentration of JM216 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004405 biolink:NamedThing sensitive to JM335 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to JM335. Cells stop growing (and may die) at a concentration of JM335 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004407 biolink:NamedThing sensitive to triplatin tetranitrate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to triplatin tetranitrate (also called BBR 3464). Cells stop growing (and may die) at a concentration of triplatin tetranitrate that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004409 biolink:NamedThing sensitive to tetraplatin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tetraplatin. Cells stop growing (and may die) at a concentration of tetraplatin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004431 biolink:NamedThing sensitive to 2-bromo-2-(((4-methylphenyl)sulfonyl)methyl)-1-indanone A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 2-bromo-2-(((4-methylphenyl)sulfonyl)methyl)-1-indanone. Cells stop growing (and may die) at a concentration of 2-bromo-2-(((4-methylphenyl)sulfonyl)methyl)-1-indanone that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004432 biolink:NamedThing sensitive to 2-bromo-1-(4-methoxyphenyl)-3-((4-methylphenyl)sulfonyl)-1-propanone A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 2-bromo-1-(4-methoxyphenyl)-3-((4-methylphenyl)sulfonyl)-1-propanone. Cells stop growing (and may die) at a concentration of 2-bromo-1-(4-methoxyphenyl)-3-((4-methylphenyl)sulfonyl)-1-propanone that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004433 biolink:NamedThing sensitive to viridicatumtoxin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to viridicatumtoxin. Cells stop growing (and may die) at a concentration of viridicatumtoxin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004434 biolink:NamedThing sensitive to 4-amino-1-methyl-1H-imidazole-5-carboselenoamide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 4-amino-1-methyl-1H-imidazole-5-carboselenoamide. Cells stop growing (and may die) at a concentration of 4-amino-1-methyl-1H-imidazole-5-carboselenoamide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004435 biolink:NamedThing sensitive to tingenone A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tingenone. Cells stop growing (and may die) at a concentration of tingenone that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004512 biolink:NamedThing sensitive to EGTA A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to EGTA. Cells stop growing (and may die) at a concentration of EGTA that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004560 biolink:NamedThing sensitive to BE49385A A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to BE49385A (a GPI synthesis inhibitor, also called YW3548). Cells stop growing (and may die) at a concentration of BE49385A that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004586 biolink:NamedThing sensitive to caffeine and hydroxyurea A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of caffeine and hydroxyurea. Cells stop growing (and may die) at concentrations of caffeine and hydroxyurea that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0004669 biolink:NamedThing sensitive to ferrozine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ferrozine. Cells stop growing (and may die) at a concentration of ferrozine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004674 biolink:NamedThing sensitive to dimethyl sulfoxide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to dimethyl sulfoxide. Cells stop growing (and may die) at a concentration of dimethyl sulfoxide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004685 biolink:NamedThing sensitive to radicicol A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to radicicol. Cells stop growing (and may die) at a concentration of radicicol that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004686 biolink:NamedThing sensitive to streptothricin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to streptothricin. Cells stop growing (and may die) at a concentration of streptothricin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004687 biolink:NamedThing sensitive to lovastatin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to lovastatin. Cells stop growing (and may die) at a concentration of lovastatin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004696 biolink:NamedThing sensitive to fatty acid A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to one or more fatty acids (usually supplied as the corresponding anions). Cells stop growing (and may die) at a concentration of fatty acid that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004697 biolink:NamedThing sensitive to 1,2-dioctanoyl-sn-glycerol A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 1,2-dioctanoyl-sn-glycerol (DiC8 DAG). Cells stop growing (and may die) at a concentration of 1,2-dioctanoyl-sn-glycerol that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004913 biolink:NamedThing sensitive to nalidixic acid A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nalidixic acid. Cells stop growing (and may die) at a concentration of nalidixic acid that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004946 biolink:NamedThing sensitive to potassium ionophore A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to one or more potassium ionophores. A potassium ionophore is any compound that can carry potassium ions through membranes of cells or organelles. FYPO_relaxed.owl FYPO:0004983 biolink:NamedThing sensitive to vorinostat A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to vorinostat. Cells stop growing (and may die) at a concentration of vorinostat that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004987 biolink:NamedThing sensitive to sunitinib A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sunitinib. Cells stop growing (and may die) at a concentration of sunitinib that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005067 biolink:NamedThing sensitive to 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane (DETA NONOate). Cells stop growing (and may die) at a concentration of 1,1-bis(2-aminoethyl)-2-hydroxy-3-oxotriazane that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005078 biolink:NamedThing sensitive to canavanine and rapamycin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of canavanine and rapamycin. Cells stop growing (and may die) at concentrations of canavanine and rapamycin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005203 biolink:NamedThing sensitive to ethionine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ethionine. Cells stop growing (and may die) at a concentration of ethionine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005250 biolink:NamedThing sensitive to caesium A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to caesium ions. Cells stop growing (and may die) at a concentration of caesium ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005251 biolink:NamedThing sensitive to tellurite A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tellurite (TeO3(2-)) ions. Cells stop growing (and may die) at a concentration of tellurite ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005252 biolink:NamedThing sensitive to tamoxifen A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tamoxifen. Cells stop growing (and may die) at a concentration of tamoxifen that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005267 biolink:NamedThing sensitive to aluminium A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to aluminium ions. Cells stop growing (and may die) at a concentration of aluminium ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005712 biolink:NamedThing sensitive to Cutin-1 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Cutin-1 (N-carbamoyl-2-(triphenyl-lambda-5-phosphanylidene)acetamide). Cells stop growing (and may die) at a concentration of Cutin-1 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005750 biolink:NamedThing sensitive to Zeocin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Zeocin (phleomycin D1). Cells stop growing (and may die) at a concentration of Zeocin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005775 biolink:NamedThing sensitive to acetaldehyde A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to acetaldehyde. Cells stop growing (and may die) at a concentration of acetaldehyde that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005825 biolink:NamedThing sensitive to iron A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to iron ions. Cells stop growing (and may die) at a concentration of iron ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005885 biolink:NamedThing sensitive to myxothiazol A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to myxothiazol. Cells stop growing (and may die) at a concentration of myxothiazol that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005889 biolink:NamedThing sensitive to sodium chloride A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium chloride. Cells stop growing (and may die) at a concentration of sodium chloride that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005919 biolink:NamedThing sensitive to TOP-53 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to TOP-53. Cells stop growing (and may die) at a concentration of TOP-53 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005984 biolink:NamedThing sensitive to Congo Red A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to the dye Congo Red. Cells stop growing (and may die) at a concentration of Congo Red that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005985 biolink:NamedThing sensitive to acetic acid A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to acetic acid. Cells stop growing (and may die) at a concentration of acetic acid that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006016 biolink:NamedThing sensitive to urea A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to urea. Cells stop growing (and may die) at a concentration of urea that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006118 biolink:NamedThing sensitive to 5-fluoroorotic acid A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 5-fluoroorotic acid (5-FOA). Cells stop growing (and may die) at a concentration of 5-FOA that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006149 biolink:NamedThing sensitive to idarubicin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to idarubicin. Cells stop growing (and may die) at a concentration of idarubicin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006225 biolink:NamedThing sensitive to tetramethylammonium A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tetramethylammonium. Cells stop growing (and may die) at a concentration of tetramethylammonium that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006226 biolink:NamedThing sensitive to spermidine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to spermidine. Cells stop growing (and may die) at a concentration of spermidine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006271 biolink:NamedThing sensitive to floxuridine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to floxuridine (5-fluoro-2'-deoxyuridine). Cells stop growing (and may die) at a concentration of floxuridine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006347 biolink:NamedThing sensitive to mechlorethamine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to mechlorethamine. Cells stop growing (and may die) at a concentration of mechlorethamine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006579 biolink:NamedThing sensitive to manganese A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to manganese. Cells stop growing (and may die) at a concentration of manganese ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006581 biolink:NamedThing sensitive to fenpropimorph A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to fenpropimorph. Cells stop growing (and may die) at a concentration of fenpropimorph that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006680 biolink:NamedThing sensitive to bisphenol A A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to bisphenol A. Cells stop growing (and may die) at a concentration of bisphenol A that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006780 biolink:NamedThing sensitive to Rbin-1 A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Rbin-1. Cells stop growing (and may die) at a concentration of Rbin-1 that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006826 biolink:NamedThing sensitive to 4-fluorophenylalanine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 4-fluorophenylalanine. Cells stop growing (and may die) at a concentration of 4-fluorophenylalanine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006836 biolink:NamedThing sensitive to magnesium chloride A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to magnesium chloride. Cells stop growing (and may die) at a concentration of magnesium chloride that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006929 biolink:NamedThing sensitive to silver nanoparticles A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to silver nanoparticles. Cells stop growing (and may die) at a concentration of silver nanoparticles that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006930 biolink:NamedThing sensitive to butylated hydroxyanisole A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to butylated hydroxyanisole (BHA). Cells stop growing (and may die) at a concentration of butylated hydroxyanisole that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006931 biolink:NamedThing sensitive to butylated hydroxytoluene A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to butylated hydroxytoluene (dibutylhydroxytoluene; BHT). Cells stop growing (and may die) at a concentration of butylated hydroxytoluene that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007037 biolink:NamedThing sensitive to phenylglyoxal A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to phenylglyoxal. Cells stop growing (and may die) at a concentration of phenylglyoxal that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007148 biolink:NamedThing sensitive to transplatin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to transplatin. Cells stop growing (and may die) at a concentration of transplatin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007152 biolink:NamedThing sensitive to camphor A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to camphor. Cells stop growing (and may die) at a concentration of camphor that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007189 biolink:NamedThing sensitive to sampangine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sampangine. Cells stop growing (and may die) at a concentration of sampangine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007330 biolink:NamedThing sensitive to formaldehyde A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to formaldehyde. Cells stop growing (and may die) at a concentration of formaldehyde that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007358 biolink:NamedThing sensitive to heavy water A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to heavy water (D2O). Cells stop growing (and may die) at a concentration of heavy water that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007461 biolink:NamedThing sensitive to histidine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to histidine. Cells stop growing (and may die) at a concentration of histidine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007514 biolink:NamedThing sensitive to manumycin A A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to manumycin A. Cells stop growing (and may die) at a concentration of manumycin A that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007522 biolink:NamedThing sensitive to tacrolimus and magnesium chloride A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of tacrolimus and magnesium chloride. Cells stop growing (and may die) at concentrations of tacrolimus and magnesium chloride that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0007538 biolink:NamedThing sensitive to paromomycin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to paromomycin. Cells stop growing (and may die) at a concentration of paromomycin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007554 biolink:NamedThing sensitive to tolnaftate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tolnaftate. Cells stop growing (and may die) at a concentration of tolnaftate that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007555 biolink:NamedThing sensitive to econazole A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to econazole. Cells stop growing (and may die) at a concentration of econazole that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007556 biolink:NamedThing sensitive to diethylstilbestrol A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to diethylstilbestrol. Cells stop growing (and may die) at a concentration of diethylstilbestrol that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007560 biolink:NamedThing sensitive to arginine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to L-arginine. Cells stop growing (and may die) at a concentration of L-arginine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007561 biolink:NamedThing sensitive to chaetoglobosin D A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to chaetoglobosin D. Cells stop growing (and may die) at a concentration of chaetoglobosin D that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007616 biolink:NamedThing sensitive to diuron A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to diuron. Cells stop growing (and may die) at a concentration of diuron that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007617 biolink:NamedThing sensitive to sodium azide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium azide (NaN3). Cells stop growing (and may die) at a concentration of sodium azide that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007717 biolink:NamedThing sensitive to potassium nitrate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to potassium chloride. Cells stop growing (and may die) at a concentration of potassium nitrate that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007812 biolink:NamedThing sensitive to stavudine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to stavudine. Cells stop growing (and may die) at a concentration of stavudine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007868 biolink:NamedThing sensitive to actin polymerization inhibitor A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a substance that inhibits actin polymerization. Cells stop growing (and may die) at a concentration of an actin polymerization inhibitor that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007921 biolink:NamedThing sensitive to benzamidine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to benzamidine. Cells stop growing (and may die) at a concentration of benzamidine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007922 biolink:NamedThing sensitive to cysteine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cysteine above normal physiological concentrations. Cells stop growing (and may die) at a concentration of cysteine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007924 biolink:NamedThing sensitive to potassium chloride and sodium dodecyl sulfate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of potassium chloride and sodium dodecyl sulfate. Cells stop growing (and may die) at concentrations of potassium chloride and sodium dodecyl sulfate that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0007925 biolink:NamedThing sensitive to sodium chloride and methyl methanesulfonate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of sodium chloride and methyl methanesulfonate. Cells stop growing (and may die) at concentrations of sodium chloride and methyl methanesulfonate that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0007926 biolink:NamedThing sensitive to calcofluor and potassium chloride A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of calcofluor and potassium chloride. Cells stop growing (and may die) at concentrations of calcofluor and potassium chloride that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0007927 biolink:NamedThing sensitive to dihydrocoumarin A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to dihydrocoumarin. Cells stop growing (and may die) at a concentration of dihydrocoumarin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007928 biolink:NamedThing sensitive to ethylenediaminetetraacetic acid A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ethylenediaminetetraacetic acid (EDTA). Cells stop growing (and may die) at a concentration of ethylenediaminetetraacetic acid (EDTA) that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007929 biolink:NamedThing sensitive to phloxine B A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to phloxine B. Cells stop growing (and may die) at a concentration of phloxine B that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007930 biolink:NamedThing sensitive to phloxine B and hydrogen peroxide A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of phloxine B and hydrogen peroxide. Cells stop growing (and may die) at concentrations of phloxine B and hydrogen peroxide that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0007931 biolink:NamedThing sensitive to egtazic acid A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to egtazic acid. Cells stop growing (and may die) at a concentration of egtazic acid that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007932 biolink:NamedThing sensitive to hydroxyurea and methyl methanesulfonate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of hydroxyurea and methyl methanesulfonate. Cells stop growing (and may die) at concentrations of hydroxyurea and methyl methanesulfonate that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0007933 biolink:NamedThing sensitive to 2,2′-dipyridyl A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 2,2′-dipyridyl. Cells stop growing (and may die) at a concentration of 2,2′-dipyridyl that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0007938 biolink:NamedThing sensitive to tea tree oil A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tea tree oil. Cells stop growing (and may die) at a concentration of tea tree oil that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0008114 biolink:NamedThing sensitive to amiloride A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to amiloride. Cells stop growing (and may die) at a concentration of amiloride that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0008167 biolink:NamedThing sensitivite to trolox A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to trolox. Cells stop growing (and may die) at a concentration of trolox that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0008194 biolink:NamedThing sensitive to trolox A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to Trolox (antioxidant). Cells stop growing (and may die) at a concentration of Trolox that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0008229 biolink:NamedThing sensitive to phosphate (Pi) A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to phosphate (Pi). Cells stop growing (and may die) at a concentration of phosphate that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0008287 biolink:NamedThing sensitive to 1-chloro-2,4-dinitrobenzene A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to 1-chloro-2,4-dinitrobenzene (CDNB). Cells stop growing (and may die) at a concentration of 1-chloro-2,4-dinitrobenzene that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0009064 biolink:NamedThing sensitive to X-rays and rapamycin during vegetative growth. A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of X-rays and ramapycin. FYPO_relaxed.owl FYPO:0009067 biolink:NamedThing sensitive to amorolfine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to amorolfine. Cells stop growing (and may die) at a concentration of amorolfine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0009069 biolink:NamedThing sensitive to ciclopirox olamine A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ciclopirox olamine. Cells stop growing (and may die) at a concentration of ciclopirox olamine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0009071 biolink:NamedThing sensitive to itraconazole A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to itraconazole. Cells stop growing (and may die) at a concentration of itraconazole that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0009080 biolink:NamedThing sensitive to calcofluor and sodium dodecyl sulfate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of calcofluor and sodium dodecyl sulfate. Cells stop growing (and may die) at concentrations of calcofluor and sodium dodecyl sulfate that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0009082 biolink:NamedThing sensitive to potassium chloride and methyl methanesulfonate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of potassium chloride and methyl methanesulfonate. Cells stop growing (and may die) at concentrations of potassium chloride and methyl methanesulfonate that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0009084 biolink:NamedThing sensitive to lithium chloride and methyl methanesulfonate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of lithium chloride and methyl methanesulfonate. Cells stop growing (and may die) at concentrations of lithium chloride and methyl methanesulfonate that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0009086 biolink:NamedThing sensitive to lithium chloride and sodium dodecyl sulfate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of lithium chloride and sodium dodecyl sulfate. Cells stop growing (and may die) at concentrations of lithium chloride and sodium dodecyl sulfate that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0009088 biolink:NamedThing sensitive to magnesium chloride and sodium dodecyl sulfate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of magnesium chloride and sodium dodecyl sulfate. Cells stop growing (and may die) at concentrations of magnesium chloride and sodium dodecyl sulfate that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0009090 biolink:NamedThing sensitive to sodium chloride and sodium dodecyl sulfate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a combination of sodium chloride and sodium dodecyl sulfate. Cells stop growing (and may die) at concentrations of sodium chloride and sodium dodecyl sulfate that allow wild type cells to grow. FYPO_relaxed.owl FYPO:0000726 biolink:NamedThing sensitive to oxidative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to oxidative stress. FYPO_relaxed.owl FYPO:0001320 biolink:NamedThing vegetative cell phenotype A phenotype that is observed at the level of an individual cell, when the cell is in the vegetative growth phase of the cell cycle. FYPO_relaxed.owl FYPO:0001790 biolink:NamedThing normal plasmid loss A cell phenotype in which plasmids are lost at the same frequency as in wild-type cells. Plasmid loss occurs when one or both daughter cells do not inherit copies of a plasmid from the mother cell, and may result from failure of plasmid replication or segregation. FYPO_relaxed.owl FYPO:0007773 biolink:NamedThing abnormal hyphal growth A phenotype in which any aspect of hyphal growth is abnormal. FYPO_relaxed.owl FYPO:0001354 biolink:NamedThing abnormal cellular component assembly during vegetative growth A cellular process phenotype in which any process of cellular component assembly at the cellular level is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000447 biolink:NamedThing abnormal protein complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which any process of protein complex assembly at the cellular level is abnormal. FYPO_relaxed.owl FYPO:0000790 biolink:NamedThing abnormal actin cortical patch organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch organization is abnormal. The process normally results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch. FYPO_relaxed.owl FYPO:0002030 biolink:NamedThing abnormal actin cable organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cable organization is abnormal. The process normally results in the assembly, arrangement of constituent parts, or disassembly of an actin cable. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts. FYPO_relaxed.owl FYPO:0002347 biolink:NamedThing abnormal stress granule assembly during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly is abnormal. FYPO_relaxed.owl FYPO:0002351 biolink:NamedThing abnormal stress granule disassembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule disassembly is abnormal. FYPO_relaxed.owl FYPO:0003409 biolink:NamedThing abnormal CENP-A containing chromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the formation of chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) is abnormal. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions. FYPO_relaxed.owl FYPO:0003583 biolink:NamedThing increased rate of Sad1 focus formation during response to DNA damage A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of formation of foci containing the protein Sad1 is increased during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0003628 biolink:NamedThing abnormal ribonucleoprotein complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which any process of ribonucleoprotein complex assembly is abnormal. FYPO_relaxed.owl FYPO:0004614 biolink:NamedThing abnormal microtubule polymerization during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule, is abnormal. FYPO_relaxed.owl FYPO:0005454 biolink:NamedThing abnormal telomere assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere assembly, i.e. the aggregation, arrangement and bonding together of a set of components to form a telomere at a double-stranded DNA end, is abnormal. FYPO_relaxed.owl FYPO:0005690 biolink:NamedThing abnormal eMTOC assembly A cellular process phenotype in which equatorial microtubule organizing center (eMTOC) assembly is abnormal. eMTOC assembly is the aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center. FYPO_relaxed.owl FYPO:0005692 biolink:NamedThing abnormal microtubule nucleation during vegetative growth A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of microtubules from one or more microtubule organizing centers (MTOCs) is abnormal. FYPO_relaxed.owl FYPO:0006061 biolink:NamedThing abnormal septin ring assembly during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septin ring assembly is abnormal. FYPO_relaxed.owl FYPO:0006064 biolink:NamedThing abnormal septin ring disassembly during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septin ring disassembly is abnormal. FYPO_relaxed.owl FYPO:0006094 biolink:NamedThing abnormal actin filament bundle assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin filament bundles is abnormal. FYPO_relaxed.owl FYPO:0006396 biolink:NamedThing abnormal iMTOC assembly A cellular process phenotype in which interphase microtubule organizing center (iMTOC) assembly is abnormal. iMTOC assembly is the aggregation, arrangement and bonding together of a set of components to form an interphase microtubule organizing center. FYPO_relaxed.owl FYPO:0007298 biolink:NamedThing abnormal protein aggregate center formation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein aggregate center formation is abnormal. Protein aggregate centers are composed of chaperones and misfolded proteins, and are reversibly formed in the nucleus and cytosol to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding. FYPO_relaxed.owl FYPO:0002342 biolink:NamedThing septated vegetative cell A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the cell contains one or more septa. FYPO_relaxed.owl FYPO:0000315 biolink:NamedThing inviable after spore germination, without cell division, with elongated, septated germ tube A phenotype in which a spore germinates to produce an elongated germ tube, and undergoes septation, but does not go on to form a viable dividing cell. FYPO_relaxed.owl FYPO:0001225 biolink:NamedThing monoseptate A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a single septum. FYPO_relaxed.owl FYPO:0002200 biolink:NamedThing inviable stubby septated vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable and has one or more septa, and the cell diameter is larger than normal and the cell length is shorter than normal. FYPO_relaxed.owl FYPO:0002406 biolink:NamedThing viable curved stubby septated vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable, contains one or more septa, and is curved along the long axis, and the cell diameter is larger than normal and the cell length is shorter than normal. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0002452 biolink:NamedThing inviable septated vegetative cell with abnormal cell morphology A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell contains one or more septa, has abnormal morphology (i.e. size, shape, or structure) and is inviable. FYPO_relaxed.owl FYPO:0003166 biolink:NamedThing monoseptate vegetative cell with binucleate and anucleate compartments A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and one septum, but both nuclei are in a single compartment on one side of the septum. Arises when a cell undergoes septation despite abnormal chromosome segregation, producing inviable daughter cells, and in which the septum forms in a position that partitions both nuclei into one compartment. Cell separation may or may not be completed. FYPO_relaxed.owl FYPO:0003171 biolink:NamedThing binucleate monoseptate cell with mitotic cell cycle arrest before cell separation A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and the mitotic cell cycle is arrested after the septum has formed, but before cells have separated. FYPO_relaxed.owl FYPO:0004750 biolink:NamedThing elongated septated vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated and has one or more septa. FYPO_relaxed.owl FYPO:0007646 biolink:NamedThing septated mononucleate vegetative cell with mislocalized nucleus and anucleate compartment A cell phenotype in which a vegetatively growing cell has one or more septa, and one nucleus that is not in the normal location. The cell also has one or more compartments with no nucleus. FYPO_relaxed.owl FYPO:0007664 biolink:NamedThing mononucleate monoseptate vegetative cell with anucleate compartment A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains one nucleus and one septum. The septum divides the cell into two compartments, one of which contains the nucleus. FYPO_relaxed.owl FYPO:0004295 biolink:NamedThing multiseptate cell A physical cellular phenotype characterized by the presence of more than one septum in a cell. FYPO_relaxed.owl FYPO:0004297 biolink:NamedThing multiseptate cell in stationary phase A cell phenotype in which a cell contains more than one septum when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0004496 biolink:NamedThing small multiseptate cell during stationary phase A cell morphology phenotype in which a cell is smaller than normal and contains more than one septum, when the cell is in a culture in stationary phase. FYPO_relaxed.owl FYPO:0006015 biolink:NamedThing multiseptate cell with shmoo A cell phenotype in which a cell has more than one septum, and forms a mating projection. FYPO_relaxed.owl FYPO:0006539 biolink:NamedThing multiseptate cell during cellular response to pheromone A cell phenotype in which a cell contains more than one septum during a cellular response to a pheromone. FYPO_relaxed.owl FYPO:0000119 biolink:NamedThing abnormal spindle assembly A cellular process phenotype in which spindle assembly is abnormal. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle. FYPO_relaxed.owl FYPO:0000151 biolink:NamedThing abnormal meiotic chromosome segregation A cellular process phenotype in which meiotic chromosome segregation is abnormal. Meiotic chromosome segregation is the entire process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle. FYPO_relaxed.owl FYPO:0000159 biolink:NamedThing abnormal chromosome condensation A cellular process phenotype in which chromosome condensation is abnormal. Chromosome condensation is the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division. FYPO_relaxed.owl FYPO:0000325 biolink:NamedThing abnormal attachment of spindle microtubules to kinetochore A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during a mitotic or meiotic nuclear division is abnormal. FYPO_relaxed.owl FYPO:0002090 biolink:NamedThing lagging chromosomes A cellular process phenotype in which homologous chromosomes or sister chromatids do not move towards the spindle poles at the same time during nuclear division, but instead one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated. Segregation may stop before completing separation of chromosomes, or may eventually be completed. FYPO_relaxed.owl FYPO:0007645 biolink:NamedThing abnormal chromosome segregation during G1 to G0 transition A cellular process phenotype in which chromosome segregation is abnormal during one or both of the cell divisions that a cell undergoes prior to entering quiescence (G0). FYPO_relaxed.owl FYPO:0001350 biolink:NamedThing abnormal microtubule cytoskeleton organization during vegetative growth A phenotype that affects the organization of the microtubule cytoskeleton in the vegetative growth phase of the life cycle. Microtubule cytoskeleton organization is a cellular process that results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. FYPO_relaxed.owl FYPO:0002761 biolink:NamedThing abnormal microtubule bundle formation A cellular process phenotype in which microtubule bundle formation, which normally results in a parallel arrangement of microtubules, is abnormal. FYPO_relaxed.owl FYPO:0003561 biolink:NamedThing abnormal prospore-specific spindle pole body remodeling A cell phenotype in which prospore-specific spindle pole body remodeling is abnormal. Prospore-specific spindle pole body remodeling takes place during the second meiotic nuclear division during ascospore formation and results in the structural reorganization of the SPB, including the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP). FYPO_relaxed.owl FYPO:0007082 biolink:NamedThing normal spindle elongation in meiosis II A cellular process phenotype in which the lengthening of the distance between poles of the meiotic spindle that occurs as part of the second meiotic nuclear division is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007099 biolink:NamedThing normal spindle elongation in meiosis I A cellular process phenotype in which the lengthening of the distance between poles of the meiotic spindle that occurs as part of the first meiotic nuclear division is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007111 biolink:NamedThing abnormal microtubule depolymerization A cellular process phenotype in which microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, is abnormal. FYPO_relaxed.owl FYPO:0007113 biolink:NamedThing abnormal microtubule cytoskeleton organization during meiotic cell cycle A phenotype that affects the organization of the microtubule cytoskeleton during all or part of the meiotic cell cycle. Microtubule cytoskeleton organization is a cellular process that results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. FYPO_relaxed.owl FYPO:0007484 biolink:NamedThing abnormal microtubule nucleation A microtubule cytoskeleton organization phenotype in which nucleation of microtubules from one or more microtubule organizing centers (MTOCs) is abnormal. FYPO_relaxed.owl FYPO:0000175 biolink:NamedThing abnormal ascospore wall assembly A sporulation phenotype in which ascospore wall assembly is abnormal. FYPO_relaxed.owl FYPO:0000196 biolink:NamedThing abnormal prospore formation A sporulation phenotype in which prospore formation is abnormal. In prospore formation, each haploid nucleus becomes encapsulated by a double membrane. FYPO_relaxed.owl FYPO:0000568 biolink:NamedThing abnormal shmoo formation A cellular process phenotype in which mating projection assembly is abnormal. FYPO_relaxed.owl FYPO:0000900 biolink:NamedThing abnormal linear element assembly A cellular process phenotype in which linear element assembly is abnormal. Linear element assembly includes the assembly of LinE complexes and their close association with chromatin to form a proteinaceous scaffold (related to the synaptonemal complex) on chromosomes during meiotic prophase. FYPO_relaxed.owl FYPO:0003000 biolink:NamedThing abolished actin filament polymerization A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin filaments from actin monomers does not occur. FYPO_relaxed.owl FYPO:0007258 biolink:NamedThing abnormal meiotic spindle pole body duplication A cellular process phenotype in which meiotic spindle pole body duplication is abnormal. FYPO_relaxed.owl FYPO:0007318 biolink:NamedThing abnormal stress granule assembly A cellular process phenotype in which stress granule assembly is abnormal. FYPO_relaxed.owl FYPO:0000120 biolink:NamedThing abnormal spindle A physical cellular phenotype in which the presence, distribution, or morphology of the mitotic or meiotic spindle is abnormal. FYPO_relaxed.owl FYPO:0002399 biolink:NamedThing abnormal microtubule cytoskeleton A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the microtubule cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0001417 biolink:NamedThing mislocalized eMTOC A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms an equatorial microtubule organizing center in an abnormal location. The normal location is at the center of the cell. FYPO_relaxed.owl FYPO:0003064 biolink:NamedThing abnormal microtubule cytoskeleton morphology A physical cellular phenotype in which the size, shape, or structure of the microtubule cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0003430 biolink:NamedThing microtubules present in decreased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer microtubules than normal. FYPO_relaxed.owl FYPO:0004315 biolink:NamedThing abnormal microtubule cytoskeleton during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, or morphology of all or part of the microtubule cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0004538 biolink:NamedThing microtubules present in increased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more microtubules than normal. FYPO_relaxed.owl FYPO:0005558 biolink:NamedThing abnormal microtubule bundle A physical cellular phenotype in which the amount, distribution, or morphology of microtubule bundles is abnormal. FYPO_relaxed.owl FYPO:0000148 biolink:NamedThing abnormal regulation of mitotic cell cycle A regulation phenotype in which regulation of the mitotic cell cycle is abnormal. FYPO_relaxed.owl FYPO:0001333 biolink:NamedThing gene expression regulation phenotype during vegetative growth A regulation phenotype that affects the regulation of gene expression in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001395 biolink:NamedThing normal activation of monopolar cell growth A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth, i.e. the initiation of growth at the old end of a cell following cell division, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001396 biolink:NamedThing normal NETO A regulation phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001928 biolink:NamedThing normal regulation of mitotic cell cycle A regulation phenotype in which regulation of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002995 biolink:NamedThing normal regulation of DNA replication A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of DNA replication is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004498 biolink:NamedThing normal positive regulation of DNA-directed DNA polymerase activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of DNA-directed DNA polymerase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004502 biolink:NamedThing normal positive regulation of ATPase activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of an ATPase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005352 biolink:NamedThing normal attachment of mitotic spindle microtubules to kinetochore A cellular process phenotype in which the physical attachment of sister chromatids to mitotic spindle microtubules is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006095 biolink:NamedThing normal actin filament bundle assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin filament bundles is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002905 biolink:NamedThing normal telomere maintenance A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere maintenance, i.e. any process that contributes to the maintenance of proper telomeric length and structure, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003286 biolink:NamedThing decreased mitotic chromosome condensation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004099 biolink:NamedThing normal mitotic chromosome condensation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005424 biolink:NamedThing decreased mitotic chromosome condensation during telophase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation occurs to a lower extent than normal during telophase of mitosis. FYPO_relaxed.owl FYPO:0000132 biolink:NamedThing abnormal septum disassembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum disassembly is abnormal; may result in the formation of chains of attached cells. FYPO_relaxed.owl FYPO:0000182 biolink:NamedThing abnormal cell wall organization during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell wall organization is abnormal. Cell wall organization results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall. FYPO_relaxed.owl FYPO:0000804 biolink:NamedThing abnormal endomembrane system organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endomembrane system organization is abnormal. Endomembrane system organization results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system, which encompasses the endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. FYPO_relaxed.owl FYPO:0000807 biolink:NamedThing abnormal kinetochore organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which kinetochore organization is abnormal. Kinetochore organization results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, the chromosomal attachment point for the spindle microtubules. FYPO_relaxed.owl FYPO:0000808 biolink:NamedThing abnormal lipid droplet organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which lipid droplet organization is abnormal. Lipid droplet organization results in the assembly, arrangement of constituent parts, or disassembly of a lipid droplet. FYPO_relaxed.owl FYPO:0000809 biolink:NamedThing abnormal mitochondrion organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion organization is abnormal. Mitochondrion organization results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion, and includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome, as well as synthesis of new mitochondrial components. FYPO_relaxed.owl FYPO:0000810 biolink:NamedThing abnormal nucleus organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleus organization is abnormal. Nucleus organization results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. FYPO_relaxed.owl FYPO:0000811 biolink:NamedThing abnormal peroxisome organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which peroxisome organization is abnormal. Peroxisome organization results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. FYPO_relaxed.owl FYPO:0000812 biolink:NamedThing abnormal vacuole organization during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole organization is abnormal. Vacuole organization results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. FYPO_relaxed.owl FYPO:0001351 biolink:NamedThing abnormal membrane organization during vegetative growth A cellular process phenotype in which cellular membrane organization is abnormal in the vegetative growth phase of the life cycle. Cellular membrane organization results in the assembly, arrangement of constituent parts, or disassembly of a lipid bilayer membrane, such as the plasma membrane or an organelle membrane. FYPO_relaxed.owl FYPO:0003089 biolink:NamedThing abnormal replication fork arrest at rDNA repeats A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at sites within the eukaryotic rDNA repeat spacer is abnormal. FYPO_relaxed.owl FYPO:0007402 biolink:NamedThing abnormal protein complex organization during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which any process of protein complex organization is abnormal. FYPO_relaxed.owl FYPO:0007739 biolink:NamedThing delayed onset of nucleolar ring disassembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleolar ring disassembly begins later than normal. Nucleolar rings are structures located at the nucleolar periphery where several nuclear factors are reversibly aggregated and sequestered during acute heat stress. They normally disassemble upon removal of heat stress. FYPO_relaxed.owl FYPO:0007416 biolink:NamedThing abnormal telomere maintenance during G0 A cellular process phenotype in which telomere maintenance, i.e. any process that contributes to the maintenance of proper telomeric length and structure, is abnormal during G0 phase. FYPO_relaxed.owl FYPO:0000123 biolink:NamedThing large vacuoles during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are larger than normal. FYPO_relaxed.owl FYPO:0007821 biolink:NamedThing large vacuoles A physical cellular phenotype in which vacuoles are larger than normal. FYPO_relaxed.owl FYPO:0007822 biolink:NamedThing large vacuoles during G0 A physical cellular phenotype in which vacuoles are larger than normal in G0 phase. FYPO_relaxed.owl FYPO:0000304 biolink:NamedThing sensitive to stress during vegetative growth A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to a stress. Typically, a cell population is deemed sensitive to a stress if cells in the population stop growing (and may die) when exposed to the stress at an intensity that allows a population of wild type cells to grow and divide. FYPO_relaxed.owl FYPO:0000850 biolink:NamedThing resistance to stress during vegetative growth A phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to a stress. Typically, a cell population is deemed resistant to a stress if cells in the population grow and divide when exposed to the stress at an intensity at which wild-type cells stop growing (and may die). FYPO_relaxed.owl FYPO:0001357 biolink:NamedThing normal vegetative cell population growth A cell population phenotype in which a population of cells grows normally (i.e. indistinguishably from wild type) in the vegetative growth phase of the life cycle. Cell population growth refers to an increase in the number of cells in the population as individual cells grow and divide. FYPO_relaxed.owl FYPO:0002684 biolink:NamedThing sensitive to phlorizin during spore germination A phenotype in which germinating spores show increased sensitivity to phlorizin. Cells stop growing (and may die) at a concentration of phlorizin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0003356 biolink:NamedThing sensitive to papuamide B during mating A phenotype in which cells show increased sensitivity to papuamide B during mating. Cells stop growing (and may die) at a concentration of papuamide B that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004185 biolink:NamedThing sensitive to myriocin during mating A phenotype in which cells show increased sensitivity to myriocin during mating. Cells stop growing (and may die) at a concentration of myriocin that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0004566 biolink:NamedThing sensitive to caffeine during meiosis II A phenotype in which cells show increased sensitivity to caffeine during the second meiotic nuclear division. Cells stop growing (and may die) at a concentration of caffeine that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0008000 biolink:NamedThing increased sensitivity to chemical in stationary phase A phenotype in which cells show increased sensitivity to a chemical when the cell population is in stationary phase. Cells stop growing (and may die) at a concentration of that chemical that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000946 biolink:NamedThing normal volume spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid, and has a normal volume. FYPO_relaxed.owl FYPO:0002380 biolink:NamedThing viable spheroid vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable, and shaped in the form of a spheroid. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged. FYPO_relaxed.owl FYPO:0002482 biolink:NamedThing inviable spheroid vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable, and shaped in the form of a spheroid. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged. FYPO_relaxed.owl FYPO:0000130 biolink:NamedThing short spindle A spindle phenotype in which the spindle is shorter than normal. FYPO_relaxed.owl FYPO:0003607 biolink:NamedThing abnormal spindle morphology A physical cellular phenotype in which the size, shape, or structure of the mitotic or meiotic spindle is abnormal. FYPO_relaxed.owl FYPO:0000730 biolink:NamedThing long spindle A spindle phenotype in which the spindle is longer than normal. FYPO_relaxed.owl FYPO:0005652 biolink:NamedThing abnormal spindle morphology during meiosis I A physical cellular phenotype in which the size, shape, or structure of the spindle is abnormal during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0005959 biolink:NamedThing multipolar spindle A physical cellular phenotype in which a spindle forms with microtubules emanating from three or more poles. FYPO_relaxed.owl FYPO:0006351 biolink:NamedThing mitotic spindle microtubules detached from spindle pole body A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle microtubules become disconnected from the spindle pole body. FYPO_relaxed.owl FYPO:0007486 biolink:NamedThing monopolar spindle during meiosis II A physical cellular phenotype in which the spindle forms with microtubules emanating from only one pole during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0000901 biolink:NamedThing abnormal microtubule dynamics during vegetative growth A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which microtubule growth (polymerization), catastrophe (the transition from growth to shrinkage), shrinkage (depolymerization), or rescue (the transition from shrinkage to growth) is abnormal. FYPO_relaxed.owl FYPO:0000904 biolink:NamedThing decreased microtubule polymerization or depolymerization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization or depolymerization, by the addition or removal of tubulin dimers respectively, occurs to a lesser extent than normal. Microtubules are thus less dynamic than normal. FYPO_relaxed.owl FYPO:0003417 biolink:NamedThing increased microtubule dwell time at cell tip A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule plus ends remain in contact with the cell cortex at cell tips for a longer time than normal. FYPO_relaxed.owl FYPO:0004625 biolink:NamedThing abnormal post-anaphase microtubule array organization A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which post-anaphase microtubule array organization is abnormal. Post-anaphase microtubule array organization is a cellular process that results in the assembly, arrangement of constituent parts, or disassembly of the post-anaphase microtubule array. FYPO_relaxed.owl FYPO:0004727 biolink:NamedThing cytoplasmic microtubule formation from nuclear microtubules A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubules are formed from existing nuclear microtubules. Normally, cytoplasmic microtubules are nucleated from microtubule organizing centers in the cytoplasm. FYPO_relaxed.owl FYPO:0005799 biolink:NamedThing decreased microtubule dwell time at cell tip A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule plus ends remain in contact with the cell cortex at cell tips for a shorter time than normal. FYPO_relaxed.owl FYPO:0006387 biolink:NamedThing abnormal mitotic spindle pole body organization A cell phenotype in which mitotic spindle pole body organization is abnormal. Mitotic spindle pole body organization is a process that results in the assembly, arrangement of constituent parts, or disassembly of the mitotic spindle pole body (SPB). FYPO_relaxed.owl FYPO:0007126 biolink:NamedThing abnormal microtubule bundle formation during mitotic spindle assembly A cellular process phenotype in which microtubule bundle formation that takes place as part of mitotic spindle assembly, and which normally results in a parallel arrangement of microtubules, is abnormal. FYPO_relaxed.owl FYPO:0007984 biolink:NamedThing abolished eMTOC disassembly A cellular process phenotype in which equatorial microtubule organizing center (eMTOC) disassembly does not take place after cell division. FYPO_relaxed.owl FYPO:0001971 biolink:NamedThing abnormal cell separation after cytokinesis resulting in chained cells A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis is abnormal, and results in the formation of a chain of cells. Cells in the chain visually resemble wild-type cells, except that they remain connected, often via remnants of septum edging material, and may continue to undergo normal mitosis and septum formation. FYPO_relaxed.owl FYPO:0001972 biolink:NamedThing abnormal cell separation after cytokinesis resulting in septated cell A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis is abnormal, and results in the formation of a septated cell. Nuclear division, contractile ring formation and constriction, and septum assembly are apparently normal, but the septum does not degrade. Additional rounds of nuclear division and cytokinesis may take place, resulting in the formation of a multiseptate cell. FYPO_relaxed.owl FYPO:0003213 biolink:NamedThing explosive cytokinetic cell separation resulting in vegetative cell lysis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation is instantaneous and asymmetrical, with a ripped primary septum. Explosive cell separation takes a few seconds (rather than 5-6 minutes as in wild type) and involves asymmetrical degradation and/or breakage of the septum edging followed by an abrupt tear of a weak primary septum and an instantaneous curvature of the secondary septum. FYPO_relaxed.owl FYPO:0003971 biolink:NamedThing inviable after spore germination, multiple cell divisions, with abnormal cytokinetic cell separation and increased septum thickness A phenotype in which a spore germinates to produce a cell of that undergoes two or more rounds of cell division in which cells do not completely separate upon cytokinesis, form septa that are thicker than normal, and then die. FYPO_relaxed.owl FYPO:0005628 biolink:NamedThing decreased rate of cell separation after cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of cell separation after cytokinesis is decreased. FYPO_relaxed.owl FYPO:0006797 biolink:NamedThing delayed onset of cell separation after cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis begins later than normal. FYPO_relaxed.owl FYPO:0006899 biolink:NamedThing asymmetric cell separation after cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis is abnormally asymmetric, i.e. cells separate asymmetrically by usually detaching one side of the new ends before the other. Normally, separate symmetrically by detaching both sides of the new ends from each other simultaneously. FYPO_relaxed.owl FYPO:0000133 biolink:NamedThing elongated multinucleate vegetative cell A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one nucleus, is longer than normal, and has a greater length:diameter ratio than normal. FYPO_relaxed.owl FYPO:0001222 biolink:NamedThing binucleate vegetative cell A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains two nuclei. FYPO_relaxed.owl FYPO:0001252 biolink:NamedThing multinucleate multiseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two or more nuclei and more than one septum per cell. FYPO_relaxed.owl FYPO:0002816 biolink:NamedThing inviable after spore germination, without cell division, multinucleate cell with elongated germ tube A phenotype in which a spore germinates to produce an elongated germ tube, and in which the nucleus divides at least once to produce a multinucleate cell. The cell does not divide, and eventually dies. FYPO_relaxed.owl FYPO:0002912 biolink:NamedThing inviable after spore germination, without cell division, elongated multinucleate cell A phenotype in which a spore germinates to produce an inviable cell that does not divide, is elongated, and contains more than one nucleus. FYPO_relaxed.owl FYPO:0002987 biolink:NamedThing inviable after spore germination, without cell division, swollen binucleate cell with central constriction A phenotype in which a spore germinates to produce an inviable cell that does not divide, contains two nuclei, has a larger diameter and volume than normal, and has an abnormal shape featuring a constriction at the center of the cell, corresponding to the cell division site. In some such cells, the diameter at the ends is much greater than in wild-type cells. FYPO_relaxed.owl FYPO:0004043 biolink:NamedThing tetranucleate vegetative cell A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains four nuclei. FYPO_relaxed.owl FYPO:0004044 biolink:NamedThing elongated tetranucleate vegetative cell A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains four nuclei and is elongated. FYPO_relaxed.owl FYPO:0004046 biolink:NamedThing tetranucleate vegetative cell with fragmented septum A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains four nuclei and pieces of a septum that does not completely bisect the cell. FYPO_relaxed.owl FYPO:0004106 biolink:NamedThing inviable multinucleate aseptate vegetative cell A cell morphology phenotype in which a vegetative cell is inviable, has no septum, and contains more than one nucleus. FYPO_relaxed.owl FYPO:0006199 biolink:NamedThing inviable stubby multinucleate vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable and has more than one nucleus, and the cell diameter is larger than normal and the cell length is shorter than normal. FYPO_relaxed.owl FYPO:0000950 biolink:NamedThing elongated aseptate vegetative cell A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell does not contain a septum and is elongated. FYPO_relaxed.owl FYPO:0001490 biolink:NamedThing inviable elongated vegetative cell A cell morphology phenotype in which a vegetative cell is inviable and longer than normal, and has a greater length:diameter ratio than normal. FYPO_relaxed.owl FYPO:0001492 biolink:NamedThing viable elongated vegetative cell A cell morphology phenotype in which a vegetative cell is viable and longer than normal, and has a greater length:diameter ratio than normal. FYPO_relaxed.owl FYPO:0001512 biolink:NamedThing branched, elongated cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is branched and elongated. FYPO_relaxed.owl FYPO:0001916 biolink:NamedThing elongated mononucleate vegetative cell A cell phenotype in which a cell contains one nucleus, is longer than normal, and has a greater length:diameter ratio than normal. FYPO_relaxed.owl FYPO:0002251 biolink:NamedThing inviable swollen elongated vegetative cell A cell morphology phenotype in which a vegetative cell is inviable and has a larger volume, and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0002479 biolink:NamedThing viable swollen elongated vegetative cell A cell morphology phenotype in which a vegetative cell is viable and has a larger volume, and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0002724 biolink:NamedThing inviable after spore germination, single or double cell division, elongated cell A phenotype in which a spore germinates to produce a cell that is elongated and undergoes one or two rounds of cell division. FYPO_relaxed.owl FYPO:0003710 biolink:NamedThing swollen pear-shaped vegetative cell A cell morphology phenotype in which a cell is shaped in the form of a pear, and has a larger volume than normal, in the vegetative growth phase of the life cycle. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell. FYPO_relaxed.owl FYPO:0005002 biolink:NamedThing elongated vegetative cell with oscillating nucleus A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated, and the nucleus undergoes oscillatory movement around its normal location. FYPO_relaxed.owl FYPO:0005103 biolink:NamedThing curved elongated vegetative cell A cell morphology phenotype in which a vegetatively growing cell is elongated, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0005115 biolink:NamedThing elongated vegetative cell with central constriction A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated and has an abnormal shape featuring a constriction at the center of the cell, corresponding to the cell division site. In some such cells, the diameter at the ends is much greater than in wild-type cells. FYPO_relaxed.owl FYPO:0005440 biolink:NamedThing swollen elongated cell with enlarged nucleus A cell morphology phenotype in which a vegetative cell is swollen, is elongated, and in which the nucleus is larger than normal. The cell contains one nucleus and no septum. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0007668 biolink:NamedThing elongated vegetative cell with cell cycle arrest in mitotic G1 phase A cell phenotype in which a vegetative cell is elongated and progression through the mitotic cell cycle is arrested in G1 phase. FYPO_relaxed.owl FYPO:0003343 biolink:NamedThing elongated multinucleate multiseptate cell, single septa between nuclei A cell morphology phenotype in which a cell is elongated, has two or more nuclei and more than one septum, and the septa not grouped together, but are located so as to form separate compartments with a single nucleus in each. FYPO_relaxed.owl FYPO:0007948 biolink:NamedThing elongated multinucleate multiseptate spore A cell phenotype in which a spore is longer than normal, is multinucleate and multiseptate. FYPO_relaxed.owl FYPO:0000134 biolink:NamedThing branched, elongated, multiseptate cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell forms one or more branches near a septum, is elongated, and has more than one septum. FYPO_relaxed.owl FYPO:0000223 biolink:NamedThing elongated multiseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is longer, and has a greater length:diameter ratio, than normal, and has more than one septum. FYPO_relaxed.owl FYPO:0001494 biolink:NamedThing inviable elongated multiseptate vegetative cell A cell morphology phenotype in which a vegetative cell is inviable, is elongated, and contains more than one septum. FYPO_relaxed.owl FYPO:0001496 biolink:NamedThing viable elongated multiseptate vegetative cell A cell morphology phenotype in which a vegetative cell is viable, is elongated, and contain more than one septum. FYPO_relaxed.owl FYPO:0004902 biolink:NamedThing curved, elongated, multinucleate multiseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated, has more than one septum and more than one nucleus, and is curved along the long axis. FYPO_relaxed.owl FYPO:0007436 biolink:NamedThing swollen elongated multiseptate vegetative cell A cell morphology phenotype in which a vegetative cell is swollen, is elongated, and contains more than one septum. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0004594 biolink:NamedThing branched, elongated, septated cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is branched, septated and elongated. FYPO_relaxed.owl FYPO:0002459 biolink:NamedThing viable branched, elongated vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, branched, septated, and elongated. FYPO_relaxed.owl FYPO:0002462 biolink:NamedThing inviable branched, elongated vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, branched, septated, and elongated. FYPO_relaxed.owl FYPO:0003610 biolink:NamedThing branched, elongated cell with branch forming adjacent to septum A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated and a branch forms adjacent to an existing septum. FYPO_relaxed.owl FYPO:0000135 biolink:NamedThing abnormal plasma membrane sterol distribution A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in the plasma membrane is abnormal. FYPO_relaxed.owl FYPO:0000813 biolink:NamedThing abnormal plasma membrane organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which plasma membrane organization is abnormal. Plasma membrane organization results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. FYPO_relaxed.owl FYPO:0007872 biolink:NamedThing abolished plasma membrane flow from cell pole to lateral region A cell phenotype observed in the vegetative growth phase of the life cycle in which bulk plasma membrane flow from the cell poles to lateral regions does not occur. FYPO_relaxed.owl FYPO:0007677 biolink:NamedThing abnormal sterol distribution A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in cellular membranes is abnormal. FYPO_relaxed.owl FYPO:0003478 biolink:NamedThing signal transduction phenotype A cellular process phenotype that affects signal transduction. Signal transduction is the process in which a signal is conveyed to trigger a change in the activity or state of a cell. It begins with reception of a signal and ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. A phenotype may affect one or more steps in one or more signal transduction pathways. FYPO_relaxed.owl FYPO:0000138 biolink:NamedThing localization phenotype A cell phenotype that affects the localization of a structure or substance in a cell. FYPO_relaxed.owl FYPO:0000140 biolink:NamedThing cellular metabolism phenotype A cellular process phenotype that affects metabolism in the cell. FYPO_relaxed.owl FYPO:0000145 biolink:NamedThing regulation phenotype A cellular process phenotype that affects the regulation of a molecular function, biological process, or biological quality. FYPO_relaxed.owl FYPO:0000298 biolink:NamedThing cellular response phenotype A cellular process phenotype that affects a response to a stimulus. FYPO_relaxed.owl FYPO:0000334 biolink:NamedThing cellular component organization phenotype A phenotype that affects a process of cellular component organization, i.e. the assembly, arrangement of constituent parts, or disassembly of a cellular component, that occurs at the cellular level. FYPO_relaxed.owl FYPO:0002114 biolink:NamedThing transmembrane transporter activity phenotype A phenotype that affects a transmembrane transporter activity. FYPO_relaxed.owl FYPO:0002057 biolink:NamedThing cell population viability A cell population phenotype that reflects the proportion of the population that survive and develop normally. FYPO_relaxed.owl FYPO:0004701 biolink:NamedThing abolished cell division timing change upon nitrogen source shift A phenotype in which a cell does not alter the timing or rate of cell division when shifted from one nitrogen source to another. Normally, cell division is delayed upon shifting from a poor to a rich nitrogen source, and accelerated upon shifting from a rich to a poor nitrogen source. FYPO_relaxed.owl FYPO:0007474 biolink:NamedThing variable cell size at division A cell population phenotype in which cells in a population do not divide at a uniform size, although each cell divides to form equal-size daughter cells. Within one population, some cells may be larger and others smaller than normal (i.e. compared to wild-type cells under the same conditions). FYPO_relaxed.owl FYPO:0008046 biolink:NamedThing decreased sexual agglutination in response to blue light A cell population phenotype that reflects decreased occurrence of sexual agglutination in response to blue light. FYPO_relaxed.owl FYPO:0009019 biolink:NamedThing increased vegetative cell population binucleate index A vegetative cell population phenotype in which the poportion of cells with two nuclei is higher than normal. FYPO_relaxed.owl FYPO:0009020 biolink:NamedThing decreased vegetative cell population binucleate index A vegetative cell population phenotype in which the poportion of cells with two nuclei is lower than normal. FYPO_relaxed.owl FYPO:0001204 biolink:NamedThing mistimed mitosis A cellular process phenotype in which cells enter mitosis earlier or later than normal, relative to cell size or DNA integrity checkpoint status. FYPO_relaxed.owl FYPO:0003972 biolink:NamedThing abnormal exit from mitosis A cellular process phenotype in which exit from mitosis is abnormal. FYPO_relaxed.owl FYPO:0004588 biolink:NamedThing abnormal mitosis following normal mitosis A cellular process phenotype in which mitosis takes place abnormally after the cell has undergone a normal mitotic nuclear division and passed through the subsequent mitotic interphase. FYPO_relaxed.owl FYPO:0005811 biolink:NamedThing abnormal nuclear membrane biogenesis involved in mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the biogenesis of nuclear membrane that normally forms part of mitosis is abnormal. FYPO_relaxed.owl FYPO:0007859 biolink:NamedThing nuclear division in absence of mitotic spindle A cellular process phenotype in which the nucleus divides into two or more fragments, each enclosed by nuclear envelope and containing a DNA mass, in a cell that does not form a mitotic spindle or undergo cytokinesis. In these cells, the nucleus does not elongate into a dumbbell shape, but instead the nuclear envelope takes on a ruffled aspect and then eventually pinches into two nuclear masses. FYPO_relaxed.owl FYPO:0000642 biolink:NamedThing abnormal chromatin organization A cellular process phenotype in which any process of chromatin organization is abnormal. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. FYPO_relaxed.owl FYPO:0001740 biolink:NamedThing increased gross chromosomal rearrangement A cell phenotype in which large chromosomal rearrangements occur more frequently than in wild type cells. Chromosomal rearrangements may include deletions, duplications, inversions, and translocations. FYPO_relaxed.owl FYPO:0001822 biolink:NamedThing mating cassette duplication A cell phenotype in which one or more of the mating cassettes is duplicated. FYPO_relaxed.owl FYPO:0002100 biolink:NamedThing abnormal 3'-5' DNA helicase activity A molecular function phenotype in which the observed rate of an 3'-5' DNA helicase activity is abnormal. FYPO_relaxed.owl FYPO:0003817 biolink:NamedThing abnormal 5'-3' DNA helicase activity A molecular function phenotype in which the observed rate of 5'-3' DNA helicase activity is abnormal. FYPO_relaxed.owl FYPO:0006656 biolink:NamedThing decreased G-quadruplex DNA unwinding A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the unwinding of G-quadruplex DNA structures occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006754 biolink:NamedThing decreased promoter-enhancer looping during glucose starvation A cellular process phenotype in which promoter-enhancer looping occurs to a lower extent than normal when the cell is subject to glucose starvation. Promoter-enhancer looping is mediated by interactions between proteins bound to DNA at promoters and at enhancers, or by a single protein binding at both sites. FYPO_relaxed.owl FYPO:0006810 biolink:NamedThing decreased gross chromosomal rearrangement A cell phenotype in which large chromosomal rearrangements occur less frequently than in wild type cells. Chromosomal rearrangements may include deletions, duplications, inversions, and translocations. FYPO_relaxed.owl FYPO:0008097 biolink:NamedThing separation of sister chromatids in stationary phase A cellular process phenotype in which sister chromatids partially separate in G2 arrest after glucose starvation (i.e. stationary phase). FYPO_relaxed.owl FYPO:0000142 biolink:NamedThing gene expression phenotype A cellular process phenotype that affects gene expression. Gene expression includes transcription, RNA processing, and, for protein-coding genes, translation and protein maturation. FYPO_relaxed.owl FYPO:0000292 biolink:NamedThing nucleic acid metabolism phenotype A cellular process phenotype that affects any nucleic acid metabolic process. FYPO_relaxed.owl FYPO:0004901 biolink:NamedThing increased oxygen consumption during stationary phase A cellular process phenotype in which the amount of oxygen consumed by cells in a given time is higher than in wild type when the population in which the cells are found is in stationary phase. FYPO_relaxed.owl FYPO:0000143 biolink:NamedThing transcription regulation phenotype A gene expression phenotype that affects the regulation of DNA-dependent transcription. FYPO_relaxed.owl FYPO:0000288 biolink:NamedThing gene expression regulation phenotype A regulation phenotype that affects the regulation of gene expression. FYPO_relaxed.owl FYPO:0000289 biolink:NamedThing translation regulation phenotype A gene expression phenotype that affects the regulation of translation. FYPO_relaxed.owl FYPO:0000574 biolink:NamedThing abnormal gene silencing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gene silencing is abnormal. FYPO_relaxed.owl FYPO:0000575 biolink:NamedThing abolished gene silencing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gene silencing does not occur. FYPO_relaxed.owl FYPO:0000576 biolink:NamedThing decreased gene silencing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of gene silencing is decreased. FYPO_relaxed.owl FYPO:0000577 biolink:NamedThing increased gene silencing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of gene silencing is increased. FYPO_relaxed.owl FYPO:0000146 biolink:NamedThing abnormal chromatin silencing at centromere A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is abnormal in centromeric regions. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core). FYPO_relaxed.owl FYPO:0000156 biolink:NamedThing abnormal chromatin silencing at silent mating-type cassette A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the silent mating-type cassettes is abnormal. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin. FYPO_relaxed.owl FYPO:0000169 biolink:NamedThing abnormal chromatin silencing at subtelomere A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at subtelomeric regions is abnormal. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin. FYPO_relaxed.owl FYPO:0000187 biolink:NamedThing abnormal heterochromatin assembly by small RNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which assembly of heterochromatin mediated by small RNA is abnormal. Small RNA-mediated heterochromatin assembly results in transcriptional silencing. FYPO_relaxed.owl FYPO:0000206 biolink:NamedThing abnormal chromatin silencing at rDNA A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at ribosomal DNA repeats is abnormal. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin. FYPO_relaxed.owl FYPO:0002353 biolink:NamedThing decreased chromatin silencing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is decreased. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core). FYPO_relaxed.owl FYPO:0004540 biolink:NamedThing increased chromatin silencing A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is incrsasd. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core). FYPO_relaxed.owl FYPO:0007598 biolink:NamedThing abolished chromatin silencing at ectopic tethering site A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing does not occur at a site where silencing can normally be triggered by the ectopic tethering of a protein. FYPO_relaxed.owl FYPO:0007599 biolink:NamedThing increased chromatin silencing at ectopic tethering site A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is increased at a site where silencing can be triggered by the ectopic tethering of a protein. FYPO_relaxed.owl FYPO:0001393 biolink:NamedThing abnormal activation of monopolar cell growth A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth, i.e. the initiation of growth at the old end of a cell following cell division, is abnormal. FYPO_relaxed.owl FYPO:0000502 biolink:NamedThing abnormally arrested mitotic cell cycle progression A cellular process phenotype in which progression through the mitotic cell cycle is arrested under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0002736 biolink:NamedThing abnormal mitotic cell cycle phase A cellular process phenotype in which a cell does not proceed normally through a specific mitotic cell cycle phase. A mitotic cell cycle phase is any of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. FYPO_relaxed.owl FYPO:0005955 biolink:NamedThing increased duration of mitotic cell cycle A cellular process phenotype in which the duration of the entire mitotic cell cycle is longer than normal. FYPO_relaxed.owl FYPO:0000149 biolink:NamedThing transport phenotype A cell process phenotype that affects a transport process. FYPO_relaxed.owl FYPO:0002333 biolink:NamedThing protein localization phenotype A cell phenotype that affects the localization of a protein in a cell. FYPO_relaxed.owl FYPO:0004853 biolink:NamedThing RNA localization phenotype A cell phenotype that affects the localization of an RNA in a cell. FYPO_relaxed.owl FYPO:0006393 biolink:NamedThing localization phenotype during meiotic cell cycle A cell phenotype that affects the localization of a structure or substance in a cell during a meiotic cell cycle. FYPO_relaxed.owl FYPO:0000475 biolink:NamedThing abnormally arrested meiosis A cellular process phenotype in which one or both meiotic nuclear division(s) is arrested under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0000477 biolink:NamedThing delayed onset of meiosis A cellular process phenotype in which one or both meiotic nuclear division(s) begins later than normal. FYPO_relaxed.owl FYPO:0000479 biolink:NamedThing premature meiosis A cellular process phenotype in which one or both meiotic nuclear division(s) begins earlier than normal. FYPO_relaxed.owl FYPO:0002773 biolink:NamedThing third meiotic division A cellular process phenotype in which a cell undergoes an abnormal nuclear division after meiosis II is complete. FYPO_relaxed.owl FYPO:0003606 biolink:NamedThing decreased duration of meiotic prophase I A cellular process phenotype in which the duration of prophase of the first meiotic nuclear division is shorter than normal. FYPO_relaxed.owl FYPO:0004610 biolink:NamedThing increased duration of meiotic prophase I A cellular process phenotype in which the duration of prophase of the first meiotic nuclear division is longer than normal. FYPO_relaxed.owl FYPO:0006526 biolink:NamedThing abnormal meiosis II A cellular process phenotype in which the second meiotic nuclear division is abnormal. FYPO_relaxed.owl FYPO:0000152 biolink:NamedThing abnormal cellular response to nitrogen starvation A stress response phenotype in which the response to nitrogen starvation is abnormal. FYPO_relaxed.owl FYPO:0000713 biolink:NamedThing abnormal cellular response to starvation A stress response phenotype in which the response to starvation for one or more nutrients is abnormal. FYPO_relaxed.owl FYPO:0001339 biolink:NamedThing abnormal cellular response to starvation during vegetative growth A stress response phenotype in which the response to starvation for one or more nutrients is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0003340 biolink:NamedThing decreased re-entry into mitotic cell cycle during recovery from stationary phase A cellular process phenotype in which the occurrence of re-entry into the mitotic cell cycle is decreased when the cell is in a population that has been in stationary phase and is then placed in conditions that allow recovery. FYPO_relaxed.owl FYPO:0003570 biolink:NamedThing normal attachment of spindle microtubules to kinetochore A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during a mitotic or meiotic nuclear division is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007553 biolink:NamedThing normal G1 to G0 transition A cellular process phenotype in which the G1 to G0 transition is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000193 biolink:NamedThing abnormal cellular response to osmotic stress A stress response phenotype observed in the vegetative growth phase of the life cycle in which a cellular response to osmotic stress is abnormal. FYPO_relaxed.owl FYPO:0000212 biolink:NamedThing abnormal cellular response to heat A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to heat is abnormal. FYPO_relaxed.owl FYPO:0001332 biolink:NamedThing abnormal regulation of translation in response to stress during vegetative growth A gene expression phenotype in which regulation of translation in response to stress is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001340 biolink:NamedThing abnormal cellular response to oxidative stress during vegetative growth A stress response phenotype in which a cellular response to oxidative stress is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000158 biolink:NamedThing DNA content increased during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of DNA in a cell is greater than normal. FYPO_relaxed.owl FYPO:0001330 biolink:NamedThing increased level of substance in cell during vegetative growth A cell phenotype in which the amount of a specific substance measured in a cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000825 biolink:NamedThing increased RNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0001041 biolink:NamedThing increased cellular thiamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of thiamine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001083 biolink:NamedThing increased polysaccharide level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell is greater than normal. FYPO_relaxed.owl FYPO:0001111 biolink:NamedThing increased cellular glutathione disulfide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione disulfide (GSSG) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001154 biolink:NamedThing increased cellular methylamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of methylamine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001198 biolink:NamedThing increased cellular calcium level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001288 biolink:NamedThing increased phospholipid level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phospholipid measured in a cell is higher than normal. A phospholipid is any lipid containing phosphoric acid as a mono- or di-ester. FYPO_relaxed.owl FYPO:0001327 biolink:NamedThing increased protein level during vegetative growth A cell phenotype in which the amount of protein measured in a cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001413 biolink:NamedThing increased cellular sulfide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-, also called acid labile sulfide) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001444 biolink:NamedThing increased cellular trehalose level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001521 biolink:NamedThing increased cellular glutathione level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione (GSH) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001552 biolink:NamedThing increased cellular zinc level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001568 biolink:NamedThing increased cellular glutamate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001661 biolink:NamedThing increased cellular cAMP level A cell phenotype in which the amount of cyclic AMP measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001730 biolink:NamedThing increased level of substance in vacuole A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the vacuole is higher than normal. FYPO_relaxed.owl FYPO:0001812 biolink:NamedThing increased 5-phosphoribosyl diphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5-phosphoribosyl diphosphate measured in a cell is greater than normal. FYPO_relaxed.owl FYPO:0001815 biolink:NamedThing increased level of Okazaki fragments A cell phenotype observed in the vegetative growth phase of the life cycle in which Okazaki fragments, the DNA segments produced by discontinuous synthesis of the lagging strand during DNA replication, are present at greater levels than normal. FYPO_relaxed.owl FYPO:0001948 biolink:NamedThing increased level of substance in cytosol A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cytosol is higher than normal. FYPO_relaxed.owl FYPO:0002006 biolink:NamedThing increased cellular iron level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of iron ions measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002227 biolink:NamedThing increased cellular triglyceride level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more triglycerides measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002235 biolink:NamedThing increased cellular sterol ester level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more sterol esters measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002317 biolink:NamedThing increased cellular squalene level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of squalene measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002318 biolink:NamedThing increased cellular ergosterol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ergosterol measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002319 biolink:NamedThing increased cellular lanosterol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of lanosterol measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002327 biolink:NamedThing increased cellular sterol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a sterol measured in a cell is higher than normal. A sterol is any natural product derived from the steroid skeleton and containing a hydroxy group in the 3 position, closely related to cholestan-3-ol. FYPO_relaxed.owl FYPO:0002548 biolink:NamedThing increased cellular 4'-phosphopantothenate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 4'-phosphopantothenate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002569 biolink:NamedThing increased cellular dCTP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dCTP measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002633 biolink:NamedThing increased cellular dTTP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dTTP measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002658 biolink:NamedThing increased cellular trehalose 6-phosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose 6-phosphate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002675 biolink:NamedThing increased cellular dTDP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dTDP measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002867 biolink:NamedThing increased cellular OMP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of orotidine 5'-phosphate (orotidine monophosphate; OMP) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002868 biolink:NamedThing increased cellular orotidine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of orotidine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003114 biolink:NamedThing increased cellular nitric oxide level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nitric oxide measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003117 biolink:NamedThing increased cellular reactive oxygen species level during cellular response to plumbagin A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal during a cellular response to plumbagin. FYPO_relaxed.owl FYPO:0003381 biolink:NamedThing increased cellular glycerol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003382 biolink:NamedThing increased cellular acetate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of acetate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003385 biolink:NamedThing increased cellular cadmium level during cellular response to cadmium ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cadmium ions measured in a cell is higher than normal during a cellular response to cadmium ion. FYPO_relaxed.owl FYPO:0003517 biolink:NamedThing increased cellular L-selenoneine level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-selenoneine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003519 biolink:NamedThing increased cellular hercynylcysteine sulfoxide level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of hercynylcysteine sulfoxide measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003520 biolink:NamedThing increased cellular hercynylselenocysteine level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of hercynylselenocysteine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003678 biolink:NamedThing increased cellular doxorubicin level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of doxorubicin measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003691 biolink:NamedThing increased cellular 5-demethoxyubiquinone-10 level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5-demethoxyubiquinone-10 ()2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone, an intermediate in ubiquinone biosynthesis) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003726 biolink:NamedThing increased cellular inositol pentakisphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any myo-inositol pentakisphosphate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003986 biolink:NamedThing increased cellular amino acid level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of an amino acid measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0004143 biolink:NamedThing increased cellular nitrite level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nitrite (NO2-) ions measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0004152 biolink:NamedThing increased cellular pyridoxal level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of pyridoxal measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0004695 biolink:NamedThing increased cellular diglyceride level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more diglycerides measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0005155 biolink:NamedThing increased cellular ergosta-5,7,22,24(28)-tetraen-3beta-ol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ergosta-5,7,22,24(28)-tetraen-3beta-ol measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0005729 biolink:NamedThing increased cellular ferrichrome level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more ferrichromes measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0005752 biolink:NamedThing increased cellular dNTP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more 2'-deoxyribonucleoside triphosphates (dNTPs) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0005882 biolink:NamedThing increased cellular gamma-glutamyl-2-aminobutyrate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of gamma-glutamyl-2-aminobutyrate (also called gamma-Glu-Abu) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006131 biolink:NamedThing increased cellular gluconate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of gluconate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006132 biolink:NamedThing increased cellular mevalonate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mevalonate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006133 biolink:NamedThing increased cellular phytosphingosine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phytosphingosine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006135 biolink:NamedThing increased cellular citrate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of citrate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006136 biolink:NamedThing increased cellular 2,3-butanediol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 2,3-butanediol measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006138 biolink:NamedThing increased cellular cis-aconitate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cis-aconitate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006577 biolink:NamedThing increased cellular P(1),P(4)-bis(5'-adenosyl) tetraphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of P(1),P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006713 biolink:NamedThing increased cellular malonyl-CoA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of malonyl-CoA measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006714 biolink:NamedThing increased cellular free fatty acid level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more free fatty acids measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006949 biolink:NamedThing increased cellular S-methyl-L-ergothioneine level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of S-methyl-L-ergothioneine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006950 biolink:NamedThing increased cellular myo-inositol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of myo-inositol measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006952 biolink:NamedThing increased cellular N2-acetyl-L-lysine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of N2-acetyl-L-lysine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006956 biolink:NamedThing increased cellular deferrichrome level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of deferrichrome measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006957 biolink:NamedThing increased cellular histidinol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidinol measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006958 biolink:NamedThing increased cellular 2-oxoglutarate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 2-oxoglutarate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006959 biolink:NamedThing increased cellular succinate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of succinate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006960 biolink:NamedThing increased cellular adenosine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of adenosine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006961 biolink:NamedThing increased cellular inosine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of inosine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006962 biolink:NamedThing increased cellular UDP-N-acetylglucosamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of UDP-N-acetylglucosamine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006963 biolink:NamedThing increased cellular 1-methyladenosine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 1-methyladenosine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006964 biolink:NamedThing increased cellular coenzyme A level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of coenzyme A measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006965 biolink:NamedThing increased cellular HMG-CoA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of HMG-CoA measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006966 biolink:NamedThing increased cellular acetyl-CoA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of acetyl-CoA measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006979 biolink:NamedThing increased cellular coenzyme Q10 level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of coenzyme Q10 measured in the cell is higher than normal. FYPO_relaxed.owl FYPO:0007186 biolink:NamedThing increased cellular reactive oxygen species level during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0007367 biolink:NamedThing increased cellular fructose 1,6-bisphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of fructose 1,6-bisphosphate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0007622 biolink:NamedThing increased cellular reactive oxygen species level during cellular response to oxidative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal when the cell is subject to oxidative stress. FYPO_relaxed.owl FYPO:0007816 biolink:NamedThing increased cellular polyphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyphosphate measured in a cell (total or free) is higher than normal. FYPO_relaxed.owl FYPO:0008225 biolink:NamedThing increased cellular phosphate (Pi) level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphate (Pi) measured in a cell (total or free) is higher than normal. FYPO_relaxed.owl FYPO:0008288 biolink:NamedThing increased cellular ceramide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a ceramide measured in a cell higher than normal. FYPO_relaxed.owl FYPO:0002729 biolink:NamedThing DNA content increased A cell phenotype in which the total amount of DNA in a cell is greater than normal. FYPO_relaxed.owl FYPO:0002730 biolink:NamedThing DNA content increased during stationary phase A cell phenotype in which the total amount of DNA in a cell is greater than normal when the cell is in a culture in stationary phase. FYPO_relaxed.owl FYPO:0004321 biolink:NamedThing altered DNA level during vegetative growth A cell phenotype in which the amount of DNA measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000453 biolink:NamedThing DNA content decreased during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of DNA in a cell is lower than normal. FYPO_relaxed.owl FYPO:0000160 biolink:NamedThing fragmented DNA A cell phenotype in which DNA is broken into small fragments. FYPO_relaxed.owl FYPO:0001229 biolink:NamedThing abnormal cell cortex morphology A physical cellular phenotype in which the size, shape, or structure of all or part of the cell cortex is abnormal. The cell cortex is the region of a cell that lies just beneath the plasma membrane. FYPO_relaxed.owl FYPO:0001898 biolink:NamedThing P-bodies present in decreased numbers A physical cellular phenotype in which cells contain fewer cytoplasmic mRNA processing bodies (P-bodies) than normal. FYPO_relaxed.owl FYPO:0001900 biolink:NamedThing small P-bodies A physical cellular phenotype in which cytoplasmic mRNA processing bodies (P-bodies) are smaller than normal. FYPO_relaxed.owl FYPO:0002397 biolink:NamedThing abnormal cytoskeleton A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0002403 biolink:NamedThing abnormal nucleus A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the nucleus is abnormal. FYPO_relaxed.owl FYPO:0002709 biolink:NamedThing spindle pole body absent from cell A cell phenotype in which the cell does not contain a detectable spindle pole body. FYPO_relaxed.owl FYPO:0002946 biolink:NamedThing abnormal cell wall A physical cellular phenotype in which the cell wall is abnormal. FYPO_relaxed.owl FYPO:0003056 biolink:NamedThing Mei2 nuclear dot absent from cell A cell phenotype in which the cell does not contain a detectable Mei2 nuclear dot complex. FYPO_relaxed.owl FYPO:0003868 biolink:NamedThing mitochondria present in decreased numbers during G0 A physical cellular phenotype in which a cell contains fewer mitochondria than normal during G0 phase. FYPO_relaxed.owl FYPO:0004292 biolink:NamedThing abnormal septum A physical cellular phenotype in which the position or morphology of all or part of the septum is abnormal. FYPO_relaxed.owl FYPO:0004585 biolink:NamedThing abnormal linear element morphology A physical cellular phenotype in which the size, shape, or structure of linear elements is abnormal. FYPO_relaxed.owl FYPO:0004607 biolink:NamedThing abnormal spindle pole body morphology A physical cellular phenotype in which the size, shape, or structure of the spindle pole body is abnormal. FYPO_relaxed.owl FYPO:0004609 biolink:NamedThing spindle pole bodies present in increased numbers during meiosis A physical cellular phenotype in which cells contain more spindle pole bodies (SPBs) than normal during one or both meiotic nuclear divisions. In this phenotype, extra SPBs typically contain normal components but seldom attach to spindle microtubules. FYPO_relaxed.owl FYPO:0004823 biolink:NamedThing abnormal rDNA copy number A physical cellular phenotype in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is abnormal (significantly greater or less than the range in wild type cells). FYPO_relaxed.owl FYPO:0004953 biolink:NamedThing abnormal prospore membrane A physical cellular phenotype in which the presence, distribution, or morphology of the prospore membrane is abnormal. FYPO_relaxed.owl FYPO:0005003 biolink:NamedThing abnormal protein complex composition A physical cellular phenotype in which the composition of a protein complex differs from normal. FYPO_relaxed.owl FYPO:0005600 biolink:NamedThing abnormal chromosome morphology A physical cellular phenotype in which the size, shape, or structure of one or more chromosomes is abnormal. FYPO_relaxed.owl FYPO:0005859 biolink:NamedThing multiple Mei2 nuclear dots present in cell A cell phenotype in which the cell contains two or more detectable Mei2 nuclear dot complexes instead of one. FYPO_relaxed.owl FYPO:0005986 biolink:NamedThing linear elements present in decreased numbers A physical cellular phenotype in which cells contain fewer linear elements than normal. FYPO_relaxed.owl FYPO:0007357 biolink:NamedThing Smp focus absent from cell A cell phenotype in which the cell does not contain a detectable Smp focus. FYPO_relaxed.owl FYPO:0007876 biolink:NamedThing decreased plasma membrane waviness at shmoo tip A cell phenotype in which the plasma membrane is smoother than normal at the shmoo tip. Normally, the plasma membrane of one of a pair of mating cells is slack shmoo tip, forming waves instead of a smooth arc. FYPO_relaxed.owl FYPO:0006188 biolink:NamedThing decreased rate of protein exchange in actomyosin contractile ring A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein exchange in the actomyosin contractile ring is decreased. Normally, proteins including actin and myosin are turned over between the contractile ring and elsewhere in the cytoplasm; exchange is faster during than before ring constriction. FYPO_relaxed.owl FYPO:0006866 biolink:NamedThing increased rate of protein exchange in actomyosin contractile ring A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein exchange in the actomyosin contractile ring is increased. Normally, proteins including actin and myosin are turned over between the contractile ring and elsewhere in the cytoplasm; exchange is faster during than before ring constriction. FYPO_relaxed.owl FYPO:0000953 biolink:NamedThing normal cellular response to chemical stimulus A cellular response phenotype in which the cellular response to a chemical stimulus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005191 biolink:NamedThing normal cellular response to stress A cellular response phenotype in which a cellular response to stress is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008031 biolink:NamedThing abnormal blue light response A cellular process phenotype in which the cellular response to blue light stimulus is abnormal. FYPO_relaxed.owl FYPO:0000163 biolink:NamedThing abnormal macroautophagy A cellular process phenotype in which macroautophagy is abnormal. Macroautophagy is the major pathway by which cells digest parts of their own cytoplasm. FYPO_relaxed.owl FYPO:0000200 biolink:NamedThing abnormal regulation of mitotic metaphase/anaphase transition A regulation phenotype in which regulation of the mitotic metaphase to anaphase transition is abnormal. FYPO_relaxed.owl FYPO:0000390 biolink:NamedThing premature passage through START of mitotic cell cycle A cellular process phenotype in which traversing the start control point of the mitotic cell cycle begins earlier than normal. FYPO_relaxed.owl FYPO:0000530 biolink:NamedThing abnormal mitotic cell cycle arrest in response to pheromone A cellular process phenotype in which the mitotic cell cycle arrest that normally occurs in response to pheromone is abnormal. FYPO_relaxed.owl FYPO:0000711 biolink:NamedThing decreased cell cycle arrest in mitotic G1 phase in response to nitrogen starvation A cellular process phenotype in which cell cycle arrest in response to nitrogen starvation occurs in G1 phase, but its occurrence is decreased. FYPO_relaxed.owl FYPO:0000712 biolink:NamedThing delayed onset of cell cycle arrest in mitotic G1 phase in response to nitrogen starvation A cellular process phenotype in which the occurrence of cell cycle arrest in response to nitrogen starvation occurs in G1 phase, but begins later than normal. FYPO_relaxed.owl FYPO:0001248 biolink:NamedThing abnormal regulation of mitotic DNA replication initiation A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of the initiation of mitotic DNA replication is abnormal. FYPO_relaxed.owl FYPO:0001933 biolink:NamedThing abnormal mitotic cell cycle regulation during cellular response to hydroxyurea A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to hydroxyurea is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to hydroxyurea. The most common abnormality is for the cell cycle to progress as in the absence of hydroxyurea. FYPO_relaxed.owl FYPO:0002017 biolink:NamedThing abnormal cell cycle arrest in mitotic interphase before NETO A cellular process phenotype in which the mitotic cell cycle is arrested during G2 phase, before new end take-off (NETO) has occurred, under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0003402 biolink:NamedThing abnormal mitotic cell cycle regulation during cellular response to osmotic stress A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to osmotic stress is abnormal. FYPO_relaxed.owl FYPO:0003489 biolink:NamedThing abnormal mitotic cell cycle regulation during cellular response to ionizing radiation A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ionizing radiation is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to ionizing radiation. The most common abnormality is for the cell cycle to progress as in the absence of ionizing radiation. FYPO_relaxed.owl FYPO:0004254 biolink:NamedThing abnormal mitotic cell cycle regulation during cellular response to UV A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ultraviolet light (UV) is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to UV. The most common abnormality is for the cell cycle to progress as in the absence of UV exposure. FYPO_relaxed.owl FYPO:0005201 biolink:NamedThing abnormal mitotic cell cycle regulation during cellular response to heat stress A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to heat stress is abnormal. FYPO_relaxed.owl FYPO:0005202 biolink:NamedThing abnormal mitotic cell cycle regulation during cellular response to rapamycin A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to rapamycin is abnormal. FYPO_relaxed.owl FYPO:0005206 biolink:NamedThing abnormal mitotic cell cycle regulation upon nitrogen source shift A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle when cells are shifted from one nitrogen source to another. Normally, cell division is delayed upon shifting from a poor to a rich nitrogen source, and accelerated upon shifting from a rich to a poor nitrogen source. FYPO_relaxed.owl FYPO:0005268 biolink:NamedThing abnormal mitotic cell cycle regulation during cellular response to methyl methanesulfonate A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to methyl methanesulfonate (MMS) is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to MMS. The most common abnormality is for the cell cycle to progress as in the absence of MMS. FYPO_relaxed.owl FYPO:0005400 biolink:NamedThing abnormal mitotic cell cycle regulation during cellular response to DNA double-strand break A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to the presence of DNA double-strand breaks is abnormal. FYPO_relaxed.owl FYPO:0000167 biolink:NamedThing increased DNA recombination at mitotic DNA replication fork barriers A cellular process phenotype in which the frequency of DNA recombination at replication fork barriers is increased. FYPO_relaxed.owl FYPO:0002340 biolink:NamedThing decreased DNA recombination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of DNA recombination is decreased. FYPO_relaxed.owl FYPO:0003352 biolink:NamedThing decreased DNA double-strand break formation at mating-type locus A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which DNA double-strand break formation occurs to a lower extent than normal during gene conversion at the mating-type locus. FYPO_relaxed.owl FYPO:0005391 biolink:NamedThing increased DNA recombination during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of DNA recombination is increased during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0005405 biolink:NamedThing increased DNA recombination at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of DNA recombination is increased in telomeric regions. FYPO_relaxed.owl FYPO:0005788 biolink:NamedThing increased gene conversion during vegetative growth A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which gene conversion occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006920 biolink:NamedThing decreased DNA recombination at mitotic DNA replication fork barriers A cellular process phenotype in which the frequency of DNA recombination at replication fork barriers is decreased. FYPO_relaxed.owl FYPO:0007005 biolink:NamedThing decreased DNA recombination downstream of mitotic DNA replication fork barriers A cellular process phenotype in which the frequency of DNA recombination downstream of replication fork barriers is decreased. FYPO_relaxed.owl FYPO:0007006 biolink:NamedThing increased DNA recombination downstream of mitotic DNA replication fork barriers A cellular process phenotype in which the frequency of DNA recombination downstream of replication fork barriers is increased. FYPO_relaxed.owl FYPO:0000168 biolink:NamedThing abnormal mitotic spindle assembly checkpoint A cell cycle checkpoint phenotype in which the spindle assembly checkpoint of a mitotic cell cycle is abnormal. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0003830 biolink:NamedThing abnormal cytokinesis checkpoint A cell cycle checkpoint phenotype in which the cytokinesis checkpoint of a mitotic cell cycle is abnormal. The cytokinesis checkpoint normally delays the G2/M transition of a mitotic cell cycle if cytokinesis was not completed correctly in the previous cell cycle. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0000598 biolink:NamedThing decreased vacuolar transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of vacuolar transport is decreased. FYPO_relaxed.owl FYPO:0000599 biolink:NamedThing decreased rate of vacuolar transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of vacuolar transport is decreased. FYPO_relaxed.owl FYPO:0000600 biolink:NamedThing delayed onset of vacuolar transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuolar transport begins later than normal. FYPO_relaxed.owl FYPO:0000676 biolink:NamedThing abnormal protein targeting to vacuole A transport phenotype observed in the vegetative growth phase of the life cycle in which protein targeting to the vacuole is abnormal. FYPO_relaxed.owl FYPO:0004370 biolink:NamedThing decreased cadmium ion import into vacuole A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of cadmium ions into the vacuole occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005508 biolink:NamedThing abnormal plasma membrane to vacuole transport A cellular process phenotype in which the transport of a substance from the plasma membrane to the vacuole is abnormal. Transport normally occurs in two stages, plasma membrane to endosome followed by endosome to vacuole transport. FYPO_relaxed.owl FYPO:0000172 biolink:NamedThing abnormal meiotic telomere clustering A meiosis phenotype in which meiotic telomere clustering is abnormal. Meiotic telomere clustering is the dynamic reorganization of telomeres in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. FYPO_relaxed.owl FYPO:0000678 biolink:NamedThing unequal homologous chromosome segregation A cellular process phenotype in which homologous chromosomes are not segregated equally to the two spindle poles in the first meiotic nuclear division. For example, both homologs of one or more chromosomes may be segregated to the same spindle pole. FYPO_relaxed.owl FYPO:0003024 biolink:NamedThing abnormal homologous chromosome pairing A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is abnormal. Synapsis is the process in which the side by side pairing and physical juxtaposition of homologous chromosomes is established and maintained. Pairing may be assayed globally or at one or more specific loci. FYPO_relaxed.owl FYPO:0003177 biolink:NamedThing abnormal meiotic homologous chromosome biorientation A cellular process phenotype in which homologous chromosome biorientation is abnormal during meiosis. Homologous chromosome biorientation is the process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, ensuring that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I. FYPO_relaxed.owl FYPO:0004393 biolink:NamedThing lagging chromosomes during meiosis I A cellular process phenotype in which homologous chromosomes or sister chromatids do not move towards the spindle poles at the same time during meiosis I, but instead one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated. Segregation may stop before completing separation of chromosomes, or may eventually be completed. FYPO_relaxed.owl FYPO:0004668 biolink:NamedThing premature homologous chromosome segregation A cellular process phenotype in which homologous chromosome segregation begins earlier than normal. FYPO_relaxed.owl FYPO:0005641 biolink:NamedThing abnormal chromosome segregation during meiosis I with premature sister kinetochore separation, lagging chromosomes, and normal chromosome separation A cellular process phenotype in which kinetochores become separated during the first meiotic nuclear division, and in which homologous chromosomes do not move towards the spindle poles at the same time during anaphase, but are eventually separated normally. FYPO_relaxed.owl FYPO:0007104 biolink:NamedThing abnormal homologous chromosome arm segregation A cellular process phenotype in which homologous chromosome segregation is abnormal along the chromosome arms. FYPO_relaxed.owl FYPO:0007756 biolink:NamedThing abnormal homologous chromosome segregation with collapsed spindle A cell phenotype in which homologous chromosome segregation is abnormal, and the meiotic spindle collapses. FYPO_relaxed.owl FYPO:0008098 biolink:NamedThing abnormal chromosome oscillation at meiotic metaphase I A cellular process phenotype in which the oscillations of homologous chromosomes which occurs at meiotic metaphase I is reduced. FYPO_relaxed.owl FYPO:0008099 biolink:NamedThing abolished homologous chromosome movement at anaphase A A cellular process phenotype in which the homologous chromosomes do not migrate toward the spindle pole in spindle elongation phase I (anaphase A). FYPO_relaxed.owl FYPO:0004093 biolink:NamedThing normal meiotic telomere clustering A meiosis phenotype in which meiotic telomere clustering is normal (i.e. indistinguishable from wild type). Meiotic telomere clustering is the dynamic reorganization of telomeres in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. FYPO_relaxed.owl FYPO:0007146 biolink:NamedThing abolished protein localization to nucleus, with protein mislocalized to cytoplasm, during meiotic cell cycle A cell phenotype in which the localization of a protein to the nucleus is abolished, and the protein is present in the cytoplasm instead, during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0004086 biolink:NamedThing abnormal meiotic centromere clustering A cellular process phenotype in which centromere clustering is abnormal during one or both meiotic nuclear divisions. Centromeres are normally located in one or two clusters away from the spindle pole body during meiosis. FYPO_relaxed.owl FYPO:0004583 biolink:NamedThing abnormal meiotic chromosome condensation A cellular process phenotype in which meiotic chromosome condensation is abnormal. FYPO_relaxed.owl FYPO:0005509 biolink:NamedThing abnormal meiotic sister chromatid segregation A cellular process phenotype in which meiotic sister chromatid segregation is abnormal. Meiotic sister chromatid segregation is the process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle. FYPO_relaxed.owl FYPO:0006760 biolink:NamedThing abnormal centromere detachment from spindle pole body during meiotic chromosome organization A cellular process phenotype in which centromeres do not detach properly from the spindle pole body (SPB) during the meiotic cell cycle. Normally, centromeres are located at the SPB during mitotic interphase, and upon entering meiosis, telomeres cluster at the SPB, followed by centromere detachment from the SPB. FYPO_relaxed.owl FYPO:0007943 biolink:NamedThing abnormal chromatin organization during meiotic cell cycle A cellular process phenotype in which any process of chromatin organization is abnormal during the meiotic cell cycle. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. FYPO_relaxed.owl FYPO:0007419 biolink:NamedThing decreased telomere tethering at nuclear periphery during G0 A cellular process phenotype in which telomere tethering at the nuclear periphery is decreased during G0 phase. FYPO_relaxed.owl FYPO:0000580 biolink:NamedThing abnormal ascospore wall biogenesis A cellular process phenotype in which ascospore wall biogenesis is abnormal. FYPO_relaxed.owl FYPO:0000585 biolink:NamedThing abolished ascospore wall biogenesis A cellular process phenotype in which ascospore wall biogenesis does not occur. FYPO_relaxed.owl FYPO:0006382 biolink:NamedThing abnormal cell wall organization during nitrogen starvation A cellular process phenotype in which cell wall organization is abnormal when the cell is subject to nitrogen starvation. Cell wall organization results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall. FYPO_relaxed.owl FYPO:0006499 biolink:NamedThing abnormal cell wall disassembly at cell fusion site A cellular process phenotype in which disassembly of the cell wall at the site of cell-cell fusion during mating is abnormal. FYPO_relaxed.owl FYPO:0000176 biolink:NamedThing abnormal DNA replication initiation A cellular process phenotype in which the initiation of DNA replication is abnormal. FYPO_relaxed.owl FYPO:0001981 biolink:NamedThing decreased rate of DNA replication A cellular process phenotype in which the rate, or speed, of DNA replication is decreased. FYPO_relaxed.owl FYPO:0003995 biolink:NamedThing abnormal DNA primase activity A molecular function phenotype in which the observed rate of DNA primase activity is abnormal. FYPO_relaxed.owl FYPO:0000737 biolink:NamedThing abnormal meiotic spindle assembly A cellular process phenotype in which assembly of the meiotic spindle is abnormal. FYPO_relaxed.owl FYPO:0006173 biolink:NamedThing abolished mitotic spindle elongation during prophase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle elongation does not occur during prophase. Normally, the spindle elongates immediately following assembly during prophase, remains at a static length during metaphase and anaphase A, and elongates further during anaphase B. FYPO_relaxed.owl FYPO:0000179 biolink:NamedThing abnormal protein targeting via MVB pathway A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein targeting to the vacuole via the multivesicular sorting pathway, leading to ubiquitin-dependent protein degradation, is abnormal. FYPO_relaxed.owl FYPO:0005547 biolink:NamedThing decreased protein targeting to vacuole, with protein secreted A cell phenotype observed in the vegetative growth phase of the life cycle in which protein targeting to the vacuole occurs to a lower extent than normal, and some of the protein is secreted. FYPO_relaxed.owl FYPO:0000845 biolink:NamedThing abnormal protein degradation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is abnormal. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0000846 biolink:NamedThing decreased protein degradation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased. FYPO_relaxed.owl FYPO:0000847 biolink:NamedThing increased protein degradation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is increased. FYPO_relaxed.owl FYPO:0003593 biolink:NamedThing abolished anaphase-promoting complex-dependent protein catabolic process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of ubiquitin-dependent protein degradation with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome, is abolished. FYPO_relaxed.owl FYPO:0004198 biolink:NamedThing decreased protein degradation during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased during mitosis. FYPO_relaxed.owl FYPO:0004332 biolink:NamedThing delayed onset of protein degradation during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation begins later than normal during mitosis. FYPO_relaxed.owl FYPO:0004734 biolink:NamedThing decreased misfolded protein degradation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of degradation of misfolded or incompletely synthesized protein is decreased. FYPO_relaxed.owl FYPO:0005182 biolink:NamedThing decreased protein degradation during cellular response to UV A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased when the cell is exposed to ultraviolet light. FYPO_relaxed.owl FYPO:0005194 biolink:NamedThing decreased protein degradation during mitotic S phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005631 biolink:NamedThing decreased rate of protein degradation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein degradation is decreased. FYPO_relaxed.owl FYPO:0006519 biolink:NamedThing decreased protein degradation during mitotic G1 phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007429 biolink:NamedThing abolished protein degradation during cellular response to DNA damage A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation does not occur during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0007878 biolink:NamedThing decreased protein degradation during cellular response to methyl methanesulfonate A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased during a cellular response to methyl methanesulfonate. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0007879 biolink:NamedThing abolished protein degradation during cellular response to methyl methanesulfonate A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation does not occur during a cellular response to methyl methanesulfonate. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0005376 biolink:NamedThing abnormal proteolysis A cellular process phenotype in which proteolysis is abnormal. Proteolysis is the hydrolysis of one or more peptide bonds within a protein. FYPO_relaxed.owl FYPO:0005377 biolink:NamedThing abolished proteolysis during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the hydrolysis of peptide bonds within a protein does not occur. All proteolysis may be affected, or only cleavage of specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0006374 biolink:NamedThing abnormal protein processing A cellular process phenotype in which protein processing is abnormal. Protein processing is the cleavage of one or more bonds within a protein that leads to the formation of mature, fully functional protein. FYPO_relaxed.owl FYPO:0006527 biolink:NamedThing decreased proteolysis A cellular process phenotype in which the occurrence of hydrolysis of peptide bonds within a protein is decreased. All proteolysis may be affected, or only cleavage of specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0000180 biolink:NamedThing abnormal cellular response to oxidative stress A stress response phenotype in which a cellular response to oxidative stress is abnormal. FYPO_relaxed.owl FYPO:0000263 biolink:NamedThing abnormal regulation of translation in response to stress A gene expression phenotype in which regulation of translation in response to stress is abnormal. FYPO_relaxed.owl FYPO:0000183 biolink:NamedThing abnormal poly(A)+ mRNA export from nucleus A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of polyadenylated mRNA from the nucleus is abnormal. FYPO_relaxed.owl FYPO:0000185 biolink:NamedThing decreased gene conversion during vegetative growth A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which gene conversion occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0000482 biolink:NamedThing decreased mitotic recombination A cellular process phenotype in which the occurrence of mitotic recombination is decreased. FYPO_relaxed.owl FYPO:0003912 biolink:NamedThing decreased double-strand break repair via homologous recombination A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair via homologous recombination occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0003044 biolink:NamedThing abnormal heterochromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly is abnormal. Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent. FYPO_relaxed.owl FYPO:0003098 biolink:NamedThing abnormal heterochromatin assembly at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly is abnormal in centromere outer repeat regions. Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent. FYPO_relaxed.owl FYPO:0005849 biolink:NamedThing decreased spatial extent of heterochromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a smaller portion of the chromosome than normal. FYPO_relaxed.owl FYPO:0007953 biolink:NamedThing increased spatial extent of heterochromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger portion of the chromosome than normal. FYPO_relaxed.owl FYPO:0005139 biolink:NamedThing abnormal meiotic recombination double-strand break repair A cellular process phenotype in which the repair of double-strand breaks formed as part of meiotic recombination is abnormal. FYPO_relaxed.owl FYPO:0000189 biolink:NamedThing abnormal mRNA splicing, via spliceosome A cellular process phenotype in which mRNA splicing via the spliceosome is abnormal. FYPO_relaxed.owl FYPO:0002915 biolink:NamedThing abnormal RNA splicing A cellular process phenotype in which RNA splicing is abnormal. All RNA splicing may be abnormal, or one splicing of or more specific RNA molecules may be selectively affected. FYPO_relaxed.owl FYPO:0002916 biolink:NamedThing increased RNA splicing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA splicing is increased. All RNA splicing may be increased, or splicing of one or more specific RNA molecules may be selectively affected. FYPO_relaxed.owl FYPO:0003040 biolink:NamedThing decreased RNA splicing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA splicing is decreased. All RNA splicing may be increased, or splicing of one or more specific RNA molecules may be selectively affected. FYPO_relaxed.owl FYPO:0003467 biolink:NamedThing altered splice site specificity A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA splice site specificity differs from normal. For example, different exons may be included or excluded, or introns in which the normally recognized 3' splice site AG nucleotides are mutated may be spliced. FYPO_relaxed.owl FYPO:0000801 biolink:NamedThing abnormal actin cytoskeleton organization during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cytoskeleton organization is abnormal. FYPO_relaxed.owl FYPO:0000198 biolink:NamedThing abnormal establishment or maintenance of actin cytoskeleton polarity during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment or maintenance of actin cytoskeleton polarity is abnormal. FYPO_relaxed.owl FYPO:0000727 biolink:NamedThing abnormal actin filament organization during vegetative growth A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of cytoskeletal structures comprising actin filaments does not occur normally. FYPO_relaxed.owl FYPO:0003524 biolink:NamedThing abnormal actin cytoskeleton organization at cell tip A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cytoskeleton organization is abnormal at one or both cell tips. FYPO_relaxed.owl FYPO:0000194 biolink:NamedThing abnormal cellular response to hydrogen peroxide A stress response phenotype observed in the vegetative growth phase of the life cycle in which a cellular response to hydrogen peroxide is abnormal. FYPO_relaxed.owl FYPO:0000236 biolink:NamedThing abnormal regulation of translation in response to oxidative stress A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to oxidative stress is abnormal. Translation may be down-regulated to a greater extent than normal, and may not be restored to normal levels post-stress. FYPO_relaxed.owl FYPO:0007793 biolink:NamedThing delayed onset of increase in RNA level during cellular response to oxidative stress A cell phenotype in which an increase in RNA level that occurs as part of a cellular response to oxidative stress begins later than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0000587 biolink:NamedThing delayed onset of sporulation A cellular process phenotype in which ascospore formation begins later than normal. FYPO_relaxed.owl FYPO:0000589 biolink:NamedThing increased rate of sporulation A cellular process phenotype in which the rate, or speed, of ascospore formation is increased, i.e. sporulation takes place more rapidly than in wild type. FYPO_relaxed.owl FYPO:0000913 biolink:NamedThing abnormal sporulation resulting in formation of ascus containing non-uniform spores A sporulation phenotype that results in the formation of an ascus that contains spores of non-uniform size and DNA content. FYPO_relaxed.owl FYPO:0001894 biolink:NamedThing abnormal sporulation resulting in formation of ascus with more or fewer than four spores A sporulation phenotype in which asci that contain more or fewer than four spores form following conjugation and subsequent sporulation. FYPO_relaxed.owl FYPO:0002711 biolink:NamedThing abnormal nuclear separation after meiosis A cellular process phenotype in which the haploid nuclei formed by meiotic nuclear division do not separate normally. Nuclei may be closer together than normal, or remain attached by an incompletely separated outer nuclear membrane, or both. FYPO_relaxed.owl FYPO:0003139 biolink:NamedThing abnormal sporulation resulting in formation of ascus containing anucleate spores A sporulation phenotype that results in the formation of an ascus that contains spore-like bodies that do not contain nuclei. FYPO_relaxed.owl FYPO:0006083 biolink:NamedThing abnormal sporulation resulting in formation of ascus with four spores A sporulation phenotype in which asci that contain four spores form following conjugation and subsequent sporulation, but sporulation is not entirely normal. FYPO_relaxed.owl FYPO:0000942 biolink:NamedThing abnormal nucleus positioning in prospore A cellular process phenotype in which nucleus localization is abnormal in a prospore. FYPO_relaxed.owl FYPO:0003062 biolink:NamedThing abnormal nuclear congression during mating A cellular process phenotype in which nuclear migration involved in conjugation with cellular fusion is abnormal. FYPO_relaxed.owl FYPO:0000464 biolink:NamedThing decreased intracellular transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of intracellular transport is decreased. FYPO_relaxed.owl FYPO:0001057 biolink:NamedThing abnormal amino acid import A cellular process phenotype in which the import of one or more amino acids into the cell is abnormal. FYPO_relaxed.owl FYPO:0002116 biolink:NamedThing abnormal transmembrane transporter activity A molecular function phenotype in which the observed rate of a specified transmembrane transporter activity is abnormal. FYPO_relaxed.owl FYPO:0003578 biolink:NamedThing abnormal vacuolar transport A cellular process phenotype in which vacuolar transport is abnormal. FYPO_relaxed.owl FYPO:0003647 biolink:NamedThing decreased sorbose import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of sorbose into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005573 biolink:NamedThing abnormal nuclear transport A cellular process phenotype in which nuclear transport is abnormal. FYPO_relaxed.owl FYPO:0005744 biolink:NamedThing abnormal protein transport A cellular process phenotype in which protein transport is abnormal. FYPO_relaxed.owl FYPO:0005971 biolink:NamedThing abnormal proton transport A cellular process phenotype in which proton transport is abnormal. FYPO_relaxed.owl FYPO:0005973 biolink:NamedThing abnormal transport during vegetative growth A phenotype in which a specific transport process is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0007873 biolink:NamedThing abnormal exocytosis A cellular process phenotype in which exocytosis is abnormal. Exocytosis is the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. A phenotype may affect exocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0007164 biolink:NamedThing decreased microtubule sliding A cellular process phenotype in which the occurrence of microtubule sliding, i.e. movement of one microtubule along another microtubule, is decreased. FYPO_relaxed.owl FYPO:0001264 biolink:NamedThing abnormal cell polarity during cellular hyperosmotic response A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment or maintenance of cell polarity is abnormal during a cellular hyperosmotic response. FYPO_relaxed.owl FYPO:0000199 biolink:NamedThing increased long tract gene conversion A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of long tract gene conversion is increased. FYPO_relaxed.owl FYPO:0006476 biolink:NamedThing premature mitotic metaphase/anaphase transition A cellular process phenotype in which the onset of anaphase of the mitotic cell cycle begins earlier than normal. FYPO_relaxed.owl FYPO:0000201 biolink:NamedThing abnormal histone deacetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone deacetylation is abnormal. FYPO_relaxed.owl FYPO:0000330 biolink:NamedThing abnormal histone modification during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle that affects histone modification. FYPO_relaxed.owl FYPO:0000456 biolink:NamedThing abnormal histone acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone acetylation is abnormal. FYPO_relaxed.owl FYPO:0000457 biolink:NamedThing abnormal histone methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation is abnormal. All histone methylation may be affected, or methylation of specific sites on specific histones may be altered. FYPO_relaxed.owl FYPO:0002591 biolink:NamedThing abnormal histone phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone phosphorylation is abnormal. All histone phosphorylation may be affected, or phosphorylation of specific sites on specific histones may be altered. FYPO_relaxed.owl FYPO:0002599 biolink:NamedThing abnormal histone H2A phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is abnormal. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be altered. FYPO_relaxed.owl FYPO:0002921 biolink:NamedThing abnormal histone ubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone ubiquitination is abnormal. FYPO_relaxed.owl FYPO:0004485 biolink:NamedThing abnormal protein deacetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the deacetylation of one or more specific proteins is abnormal. FYPO_relaxed.owl FYPO:0004486 biolink:NamedThing abolished protein deacetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the deacetylation of one or more specific proteins, or of specific protein sites, does not occur. FYPO_relaxed.owl FYPO:0000506 biolink:NamedThing abnormal nuclear export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear export is abnormal. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected. FYPO_relaxed.owl FYPO:0000345 biolink:NamedThing abnormal protein export from nucleus during vegetative growth A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of protein from the nucleus is abnormal. Export of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0000508 biolink:NamedThing decreased nuclear export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of nuclear export is decreased. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected. FYPO_relaxed.owl FYPO:0003188 biolink:NamedThing abnormal protein import into nucleus during vegetative growth A transport phenotype observed in the vegetative growth phase of the life cycle in which the import of protein into the nucleus is abnormal. Import of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007608 biolink:NamedThing abnormal RNA localization during meiotic cell cycle A cell phenotype in which the localization of an RNA in a cell is abnormal during the meiotic cell cycle. An RNA may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. FYPO_relaxed.owl FYPO:0005502 biolink:NamedThing abnormal transcription A cellular process phenotype in which transcription is abnormal in extent, timing, start or termination site, etc. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0006548 biolink:NamedThing increased gene expression A cellular process phenotype in which gene expression occurs to a greater extent than normal. One or more parts of gene expression, such as transcription or translation, may be affected, and all genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0006549 biolink:NamedThing decreased gene expression A cellular process phenotype in which gene expression occurs to a lower extent than normal. One or more parts of gene expression, such as transcription or translation, may be affected, and all genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0000968 biolink:NamedThing normal cellular response to stress during vegetative growth A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to a stress is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001318 biolink:NamedThing normal cellular response to chemical stimulus during vegetative growth A cellular response phenotype in which the cellular response to a chemical stimulus is normal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0004726 biolink:NamedThing normal mitotic spindle orientation correction A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle orientation correction is normal (i.e. indistinguishable from wild type). Spindle orientation correction is the process by which a spindle that has formed in, or moved into, an incorrect orientation is restored to the correct orientation (parallel to the long axis of the cell). FYPO_relaxed.owl FYPO:0005213 biolink:NamedThing normal regulation of translation in response to stress during vegetative growth A gene expression phenotype in which regulation of translation in response to stress is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0005230 biolink:NamedThing normal regulation of translation in response to UV A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to ultraviolet light is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007090 biolink:NamedThing abnormal regulation of transcription by nutrient A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription as a consequence of the presence of one or more specific nutrient(s) is abnormal. For example, specific genes that are normally not transcribed in the presence of the nutrient may be transcribed in the mutant, or vice versa. FYPO_relaxed.owl FYPO:0007134 biolink:NamedThing normal septation initiation network signaling A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septation initiation network signaling is normal (i.e. indistinguishable from wild type). SIN signaling is mediated by the small GTPase Ras, and results in the initiation of contraction of the contractile ring at the beginning of cytokinesis and cell division by septum formation. FYPO_relaxed.owl FYPO:0000209 biolink:NamedThing abnormal attachment of spindle microtubules to kinetochore during meiosis I A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during the first meiotic nuclear division is abnormal. FYPO_relaxed.owl FYPO:0000925 biolink:NamedThing unequal meiotic chromosome segregation A cellular process phenotype in which chromosomes are not segregated equally to the two spindle poles in a meiotic nuclear division. FYPO_relaxed.owl FYPO:0002091 biolink:NamedThing lagging meiotic chromosomes A cellular process phenotype in which homologous chromosomes or sister chromatids do not move towards the spindle poles at the same time during meiosis I or meiosis II, but instead one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated. Segregation may stop before completing separation of chromosomes, or may eventually be completed. FYPO_relaxed.owl FYPO:0005648 biolink:NamedThing sister kinetochore dissociation in meiotic metaphase I A physical cellular phenotype in which sister kinetochores separate during the first meiotic nuclear division. Normally sister kinetochores remain together until meiosis II. FYPO_relaxed.owl FYPO:0006372 biolink:NamedThing incomplete meiotic chromosome segregation, with chromosomal bridge A cellular process phenotype in which homologous chromosomes or sister chromatids do not separate completely during meiosis I or meiosis II, and partially separated DNA masses are connected by one or more bridges formed of chromatin. FYPO_relaxed.owl FYPO:0002651 biolink:NamedThing merotelic kinetochore attachment A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during a mitotic or meiotic nuclear division results in the connection of a single kinetochore to both spindle poles. FYPO_relaxed.owl FYPO:0004213 biolink:NamedThing abnormal attachment of mitotic spindle microtubules to kinetochore A cellular process phenotype in which the physical attachment of sister chromatids to mitotic spindle microtubules is abnormal. FYPO_relaxed.owl FYPO:0000495 biolink:NamedThing abnormal mitochondrial transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial transport is abnormal. FYPO_relaxed.owl FYPO:0005972 biolink:NamedThing decreased proton export during cellular response to glucose stimulus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of proton export is decreased during a cellular response to glucose stimulus. FYPO_relaxed.owl FYPO:0008228 biolink:NamedThing abnormal phosphate export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of phosphate ions (Pi) out of a cell is abnormal. FYPO_relaxed.owl FYPO:0000215 biolink:NamedThing abnormal intracellular protein transport during vegetative growth A transport phenotype observed in the vegetative growth phase of the life cycle in which intracellular protein transport is abnormal. FYPO_relaxed.owl FYPO:0000536 biolink:NamedThing abnormal protein secretion during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein secretion is abnormal. FYPO_relaxed.owl FYPO:0000541 biolink:NamedThing decreased protein transport during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein transport is decreased. FYPO_relaxed.owl FYPO:0000542 biolink:NamedThing increased rate of protein transport during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein transport is increased. FYPO_relaxed.owl FYPO:0000216 biolink:NamedThing abnormal negative regulation of mitotic DNA replication initiation A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is abnormal. May result in re-replication of all or part of the genome. FYPO_relaxed.owl FYPO:0001249 biolink:NamedThing increased origin firing efficiency A regulation phenotype observed in the vegetative growth phase of the life cycle in which the probability that a DNA replication will initiate at a particular replication origin is higher than in wild type. In cells with increased origin firing efficiency, genomic DNA replication initiates from more origins than wild type, and is completed in more, smaller segments, than wild type. FYPO_relaxed.owl FYPO:0001250 biolink:NamedThing decreased origin firing efficiency A regulation phenotype observed in the vegetative growth phase of the life cycle in which the probability that a DNA replication will initiate at a particular replication origin is lower than in wild type. In cells with decreased origin firing efficiency, genomic DNA replication initiates from fewer origins than wild type, and is completed in fewer, larger segments, than wild type. FYPO_relaxed.owl FYPO:0004597 biolink:NamedThing replication origin firing during mitotic G2 phase A regulation phenotype observed in the vegetative growth phase of the life cycle in which DNA replication is initiated at one or more origins during G2 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005758 biolink:NamedThing abnormal regulation of mitotic DNA replication initiation from late origin A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of the initiation of mitotic DNA replication from late-firing origins is abnormal. FYPO_relaxed.owl FYPO:0007232 biolink:NamedThing abnormal regulation of mitotic DNA replication initiation from early origin A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of the initiation of mitotic DNA replication from early-firing origins is abnormal. FYPO_relaxed.owl FYPO:0004757 biolink:NamedThing abnormal negative regulation of DNA replication initiation A regulation phenotype in which negative regulation of the initiation of DNA-dependent DNA replication is abnormal. May result in re-replication of all or part of the genome. FYPO_relaxed.owl FYPO:0004758 biolink:NamedThing abnormal negative regulation of premeiotic DNA replication initiation A regulation phenotype in which negative regulation of the initiation of premeiotic DNA replication is abnormal. May result in re-replication of all or part of the genome. FYPO_relaxed.owl FYPO:0000218 biolink:NamedThing decreased Mre11 complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of Mre11 complex assembly is decreased. FYPO_relaxed.owl FYPO:0000448 biolink:NamedThing abnormal MCM complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which MCM complex assembly is abnormal. FYPO_relaxed.owl FYPO:0004595 biolink:NamedThing abnormal gamma-tubulin complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gamma-tubulin complex assembly is abnormal. FYPO_relaxed.owl FYPO:0005053 biolink:NamedThing abnormal RITS complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RITS complex assembly is abnormal. FYPO_relaxed.owl FYPO:0005075 biolink:NamedThing decreased anaphase-promoting complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of anaphase-promoting complex assembly is decreased. FYPO_relaxed.owl FYPO:0005220 biolink:NamedThing abnormal protein oligomerization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein oligomerization is abnormal. FYPO_relaxed.owl FYPO:0005387 biolink:NamedThing decreased eukaryotic translation initiation factor 2B complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of eukaryotic translation initiation factor 2B complex assembly is decreased. FYPO_relaxed.owl FYPO:0006463 biolink:NamedThing abnormal mRNA cleavage and polyadenylation specificity factor complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mRNA cleavage and polyadenylation specificity factor complex assembly is abnormal. FYPO_relaxed.owl FYPO:0006563 biolink:NamedThing abolished MBF complex assembly during mitotic G1 phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which MBF complex assembly is abolished during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007062 biolink:NamedThing decreased Atg1/ULK1 kinase complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of Atg1/ULK1 kinase complex assembly is decreased. FYPO_relaxed.owl FYPO:0007122 biolink:NamedThing decreased mitochondrial respiratory chain complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of assembly of one or more mitochondrial respiratory chain complexes is decreased. FYPO_relaxed.owl FYPO:0007718 biolink:NamedThing abnormal SMN complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which SMN complex assembly is abnormal. FYPO_relaxed.owl FYPO:0008117 biolink:NamedThing abnormal de novo SAGA complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which de novo assembly of the SAGA complex is abnormal. FYPO_relaxed.owl FYPO:0008235 biolink:NamedThing abolished nuclear RNA-directed RNA polymerase complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of the nuclear RNA-directed RNA polymerase complex is abolished. FYPO_relaxed.owl FYPO:0000219 biolink:NamedThing increased protein oxidation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidation of one or more specific proteins, or of specific protein sites, is increased, resulting in the accumulation of proteins with oxidative modifications including carbonylated proteins. FYPO_relaxed.owl FYPO:0000547 biolink:NamedThing increased protein modification during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein modification is increased. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0001038 biolink:NamedThing increased protein phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0002510 biolink:NamedThing increased protein palmitoylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the palmitoylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0003863 biolink:NamedThing increased protein oxidation A cellular process phenotype in which the occurrence of oxidation of one or more specific proteins, or of specific protein sites, is increased, resulting in the accumulation of proteins with oxidative modifications including carbonylated proteins. FYPO_relaxed.owl FYPO:0003862 biolink:NamedThing increased protein oxidation in stationary phase A cellular process phenotype in which the occurrence of oxidation of one or more specific proteins, or of specific protein sites, is increased, resulting in the accumulation of proteins with oxidative modifications including carbonylated proteins, in cells in a population in stationary phase. FYPO_relaxed.owl FYPO:0000220 biolink:NamedThing increased centromeric outer repeat transcript level A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere outer repeat region are present at greater levels than normal. FYPO_relaxed.owl FYPO:0004982 biolink:NamedThing increased centromeric transcript level A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromeric region are present at greater levels than normal. FYPO_relaxed.owl FYPO:0004689 biolink:NamedThing increased cenH-derived RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from cenH measured in a cell is higher than normal. cenH is a region located between mat2-P and mat3-M that is homologous to centromeric repeats, and that produces non-coding RNAs and small interfering RNAs. FYPO_relaxed.owl FYPO:0006353 biolink:NamedThing increased centromere central core transcript level A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere central core are present at greater levels than normal. Normally, the central core is not transcribed. FYPO_relaxed.owl FYPO:0008176 biolink:NamedThing increased centromeric inner repeat transcript level A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere inner repeat region are present at greater levels than normal. FYPO_relaxed.owl FYPO:0002002 biolink:NamedThing multiseptate vegetative cell, septa grouped A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has one or more nuclei and more than one septum, and the septa are grouped together between two compartments, one or more of which may contain one or multiple nuclei. FYPO_relaxed.owl FYPO:0004076 biolink:NamedThing inviable after spore germination, single or double cell division, elongated multiseptate cell A phenotype in which a spore germinates to produce a cell that is elongated, has more than one septum, and undergoes one or two rounds of cell division. FYPO_relaxed.owl FYPO:0004657 biolink:NamedThing inviable mononucleate multiseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, and has one nucleus and more than one septum. FYPO_relaxed.owl FYPO:0004843 biolink:NamedThing multiseptate vegetative cell with binucleate and anucleate compartments A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and more than one septum, and the septa are grouped together between two compartments, one contains both nuclei. FYPO_relaxed.owl FYPO:0005027 biolink:NamedThing inviable after spore germination, without cell division, swollen binucleate multiseptate cell with central constriction A phenotype in which a spore germinates to produce an inviable cell that does not divide, has a larger diameter and volume than normal, contains two nuclei and more than one septum, and has an abnormal shape featuring a constriction at the center of the cell, corresponding to the cell division site. In some such cells, the diameter at the ends is much greater than in wild-type cells. FYPO_relaxed.owl FYPO:0005855 biolink:NamedThing inviable after spore germination, single cell division, multiseptate cell A phenotype in which a spore germinates to produce a cell that undergoes a single round of cell division to produce daughter cells that have two or more septa apiece, which then die. FYPO_relaxed.owl FYPO:0005869 biolink:NamedThing inviable stubby multiseptate vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable and has one nucleus and more than one septum, and the cell diameter is larger than normal and the cell length is shorter than normal. FYPO_relaxed.owl FYPO:0006117 biolink:NamedThing multiseptate spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid and has two or more septa. FYPO_relaxed.owl FYPO:0007138 biolink:NamedThing inviable small multiseptate vegetative cell A cell morphology phenotype in which a vegetative cell is inviable, has an abnormally low volume, and contains more than one septum. FYPO_relaxed.owl FYPO:0007584 biolink:NamedThing multiseptate vegetative cell with normal cell length A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which cell length is normal, and the cell contains more than one septum. FYPO_relaxed.owl FYPO:0002845 biolink:NamedThing inviable swollen elongated septated vegetative cell A cell morphology phenotype in which a vegetative cell is inviable, is swollen, is elongated, and contains one or more septa. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0004979 biolink:NamedThing elongated monoseptate vegetative cell A cell phenotype in which a cell contains one septum, is longer than normal, and has a greater length:diameter ratio than normal. FYPO_relaxed.owl FYPO:0005023 biolink:NamedThing inviable elongated septated mononucleate vegetative cell A cell phenotype in which a cell is inviable, contains one nucleus and one or more septa and is elongated. Cells with this phenotype are inviable, and the nucleus is not in the normal location. FYPO_relaxed.owl FYPO:0000225 biolink:NamedThing snowman-shaped spore A cell morphology phenotype in which a spore assumes a snowman shape, having two connected parts, roughly spherical, of different sizes. FYPO_relaxed.owl FYPO:0001489 biolink:NamedThing inviable vegetative cell A cell phenotype in which a cell is inviable in the phase of the life cycle during which wild type cells undergo vegetative growth. FYPO_relaxed.owl FYPO:0000316 biolink:NamedThing inviable after spore germination A viability phenotype in which a spore germinates but fails to produce dividing cells that can survive under normal conditions. FYPO_relaxed.owl FYPO:0000647 biolink:NamedThing vegetative cell lysis An inviable phenotype in which a vegetative cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised. FYPO_relaxed.owl FYPO:0002105 biolink:NamedThing inviable vegetative cell with normal cell shape A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal shape but is inviable. FYPO_relaxed.owl FYPO:0002199 biolink:NamedThing inviable vegetative cell with normal cell morphology A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal morphology (i.e. size, shape, and structure) but is inviable. FYPO_relaxed.owl FYPO:0003931 biolink:NamedThing inviable aseptate vegetative cell A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell has no septum and is inviable. FYPO_relaxed.owl FYPO:0003976 biolink:NamedThing inviable vegetative cell with fragmented nuclear envelope during mitotic telophase A cell morphology phenotype in which a vegetatively growing cell is inviable, and has a nuclear envelope that is broken into multiple small fragments during mitotic telophase. FYPO_relaxed.owl FYPO:0003977 biolink:NamedThing inviable vegetative cell with nuclear pore aggregation in cytoplasm during mitotic telophase A cell morphology phenotype in which a vegetatively growing cell is inviable, and one or more clusters of nuclear pores are present in the cytoplasm during mitotic telophase. FYPO_relaxed.owl FYPO:0004658 biolink:NamedThing inviable binucleate multiseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, and has two nuclei and more than one septum. FYPO_relaxed.owl FYPO:0004827 biolink:NamedThing inviable vegetative cell with cell death during mitosis A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell dies as it goes through mitosis, usually as a result of abnormal chromosome and spindle dynamics. FYPO_relaxed.owl FYPO:0006430 biolink:NamedThing inviable mononucleate vegetative cell A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, and contains a single nucleus. FYPO_relaxed.owl FYPO:0003250 biolink:NamedThing premature septum assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septum assembly begins earlier than normal, e.g. before metaphase is complete. FYPO_relaxed.owl FYPO:0007743 biolink:NamedThing premature septum assembly during mitotic interphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septum assembly begins during interphase of the mitotic cell cycle. Septum assembly normally begins during M phase. FYPO_relaxed.owl FYPO:0005979 biolink:NamedThing abnormal actin filament bundle organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin filament bundle organization is abnormal. The process normally results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle. Actin filament bundles are assemblies of actin filaments organized along a single axis. FYPO_relaxed.owl FYPO:0006029 biolink:NamedThing decreased actin filament depolymerization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin filament depolymerization, i.e. the removal of actin monomers from a filament, occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006207 biolink:NamedThing decreased rate of actin filament depolymerization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin filament depolymerization, i.e. the removal of actin monomers from a filament, is decreased. FYPO_relaxed.owl FYPO:0007060 biolink:NamedThing decreased actin filament depolymerization involved in actomyosin contractile ring assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin filament polymerization, i.e. the addition of actin monomers to a filament, occurs to a lower extent than normal as part of contractile ring assembly during cytokinesis. FYPO_relaxed.owl FYPO:0000232 biolink:NamedThing split actomyosin contractile ring A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the actomyosin contractile ring splits upon initiation of contraction during anaphase B, resulting in the formation of a primary ring that undergoes constriction and a secondary ring that does not constrict. FYPO_relaxed.owl FYPO:0003338 biolink:NamedThing abnormal actomyosin contractile ring morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the actomyosin contractile ring is abnormal. FYPO_relaxed.owl FYPO:0000233 biolink:NamedThing long cytoplasmic microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are longer than normal. FYPO_relaxed.owl FYPO:0003787 biolink:NamedThing long mitotic spindle microtubules protruding beyond spindle pole body A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form mitotic spindle microtubules that are longer than normal, and extend beyond the spindle pole body. The protruding spindle microtubules are surrounded by an extension of the nuclear envelope. FYPO_relaxed.owl FYPO:0004021 biolink:NamedThing long polar microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form polar microtubules that are longer than normal. Polar microtubules are the spindle microtubules that come from each pole and overlap at the spindle midzone. FYPO_relaxed.owl FYPO:0004724 biolink:NamedThing long nuclear microtubules protruding through nuclear envelope during interphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form nuclear microtubules during interphase of the mitotic cell cycle that are longer than normal, and are partially or completely surrounded by an extension of the nuclear envelope. These microtubules usually have one end in close proximity to a spindle pole body, and may puncture the nuclear envelope to extent into the cytoplasm. FYPO_relaxed.owl FYPO:0006044 biolink:NamedThing long mitotic kinetochore microtubules with kinetochore at tip of nuclear envelope protrusion A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form mitotic spindle microtubules that are longer than normal, and the protruding kinetochore microtubules are surrounded by an extension of the nuclear envelope, with the kinetochore-attached end at the distal tip of the protrusion. FYPO_relaxed.owl FYPO:0000234 biolink:NamedThing abnormal cytoplasmic interphase microtubule nucleation A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules is abnormal during interphase of the mitotic cell cycle. Normally, microtubules are nucleated from interphase microtubule organizing centers (iMTOCs) and from the cytoplasmic face of the spindle pole body (SPB). FYPO_relaxed.owl FYPO:0005693 biolink:NamedThing abolished cytoplasmic microtubule nucleation A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules from one or more microtubule organizing centers (MTOCs) is does not occur. FYPO_relaxed.owl FYPO:0006335 biolink:NamedThing decreased microtubule nucleation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleation of microtubules from one or more microtubule organizing centers (MTOCs) occurs to a lesser extent than normal. FYPO_relaxed.owl FYPO:0007422 biolink:NamedThing abolished mitotic spindle microtubule nucleation from spindle pole body A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of spindle microtubules from the spindle pole body (SPB) does not occur. FYPO_relaxed.owl FYPO:0007428 biolink:NamedThing delayed onset of mitotic spindle microtubule nucleation from old spindle pole body A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the nucleation of microtubules from the old mitotic spindle pole body begins later than normal. FYPO_relaxed.owl FYPO:0000235 biolink:NamedThing abnormal regulation of translation in response to osmotic stress A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to osmotic stress is abnormal. Translation may be down-regulated to a greater extent than normal, and may not be restored to normal levels post-stress. FYPO_relaxed.owl FYPO:0000237 biolink:NamedThing abnormal regulation of translation in response to nitrogen starvation A gene expression phenotype in which regulation of translation in response to nitrogen starvation is abnormal. Translation may be down-regulated to a greater extent than normal, and may not be restored to normal levels upon prolonged nitrogen starvation. FYPO_relaxed.owl FYPO:0000238 biolink:NamedThing inviable cell upon G0 to G1 transition A cell phenotype in which a cell fails to resume growth after several days in G0 phase. The inviable cells show some features characteristic of apoptosis, including loss of DNA. FYPO_relaxed.owl FYPO:0001165 biolink:NamedThing inviable cell following anaerobic growth A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell that is exposed to anaerobic conditions fails to grow upon being returned to aerobic conditions, and eventually dies. FYPO_relaxed.owl FYPO:0002109 biolink:NamedThing inviable tapered cell A cell morphology phenotype in which a cell is inviable, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell. FYPO_relaxed.owl FYPO:0002151 biolink:NamedThing inviable spore A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive. An inviable spore does not germinate. FYPO_relaxed.owl FYPO:0002488 biolink:NamedThing cell lysis An inviable phenotype in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised. FYPO_relaxed.owl FYPO:0000239 biolink:NamedThing increased transcription from MCB promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more MluI cell cycle box factor elements (MCBs) occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000780 biolink:NamedThing increased transcription during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0001460 biolink:NamedThing increased transcription from CDRE promoter in response to calcium ion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a calcineurin-dependent response element (CDRE)-containing promoter is increased following a calcium ion stimulus. FYPO_relaxed.owl FYPO:0001854 biolink:NamedThing increased transcription during cellular response to iron A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal during a cellular response to iron ions. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002781 biolink:NamedThing increased transcription during cellular response to nitric oxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal during a cellular response to nitric oxide. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002782 biolink:NamedThing increased transcription during cellular response to salt stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal during a cellular response to a salt stress. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002895 biolink:NamedThing increased transcription during cellular response to calcium ion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal during a cellular response to calcium ions. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002908 biolink:NamedThing increased transcription at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal in telomeric regions. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002913 biolink:NamedThing increased antisense RNA transcription A cellular process phenotype observed in the vegetative growth phase of the life cycle in which antisense RNA transcription occurs to a greater extent than normal. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002914 biolink:NamedThing increased intergenic transcription A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal in intergenic regions. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0004565 biolink:NamedThing increased transcription of pheromone response gene mRNA during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription of pheromone response genes is increased. Pheromone response genes are normally transcribed in response to a pheromone stimulus. FYPO_relaxed.owl FYPO:0005495 biolink:NamedThing increased transcription from CRE promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005886 biolink:NamedThing increased transcription from HSE promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more heat shock elements (HSEs) occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006761 biolink:NamedThing increased transcription during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a greater extent than normal during a cellular response to hydroxyurea. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0007297 biolink:NamedThing increased transcription from SRE promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more SRE elements occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007612 biolink:NamedThing increased transcription from STREP promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more STREP motifs occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000242 biolink:NamedThing normal growth on ammonia nitrogen source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing ammonia as the nitrogen source. FYPO_relaxed.owl FYPO:0000243 biolink:NamedThing normal growth on proline nitrogen source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing L-proline as the nitrogen source. FYPO_relaxed.owl FYPO:0000674 biolink:NamedThing normal cell population growth at high temperature A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) at a high temperature. FYPO_relaxed.owl FYPO:0000954 biolink:NamedThing normal growth on nickel cation A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing nickel cations. FYPO_relaxed.owl FYPO:0000955 biolink:NamedThing normal growth on lead ion A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing lead ions. FYPO_relaxed.owl FYPO:0000956 biolink:NamedThing normal growth on bismuth A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing bismuth ions. FYPO_relaxed.owl FYPO:0000957 biolink:NamedThing normal growth on methyl methanesulfonate A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing methyl methanesulfonate. FYPO_relaxed.owl FYPO:0000958 biolink:NamedThing normal growth on mercaptoethanol A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mercaptoethanol. FYPO_relaxed.owl FYPO:0000959 biolink:NamedThing normal growth on sodium dodecyl sulfate A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sodium dodecyl sulfate (SDS. FYPO_relaxed.owl FYPO:0000960 biolink:NamedThing normal growth on ethanol A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing ethanol. FYPO_relaxed.owl FYPO:0000961 biolink:NamedThing normal growth on sorbitol A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sorbitol. FYPO_relaxed.owl FYPO:0000962 biolink:NamedThing normal growth on hydrogen peroxide A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing hydrogen peroxide. FYPO_relaxed.owl FYPO:0000963 biolink:NamedThing normal growth on hydroxyurea A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing hydroxyurea. FYPO_relaxed.owl FYPO:0000964 biolink:NamedThing normal growth on thiabendazole A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing thiabendazole. FYPO_relaxed.owl FYPO:0000969 biolink:NamedThing normal growth during cellular response to UV A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to ultraviolet light. FYPO_relaxed.owl FYPO:0000978 biolink:NamedThing normal growth on mevastatin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mevastatin. FYPO_relaxed.owl FYPO:0000979 biolink:NamedThing normal growth on miconazole A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing miconazole. FYPO_relaxed.owl FYPO:0000980 biolink:NamedThing normal growth on amphotericin B A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing amphotericin B. FYPO_relaxed.owl FYPO:0001016 biolink:NamedThing normal growth on actinomycin D A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing actinomycin D. FYPO_relaxed.owl FYPO:0001020 biolink:NamedThing normal growth on calcium A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing calcium ions. FYPO_relaxed.owl FYPO:0001021 biolink:NamedThing normal growth during cellular response to osmotic stress A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to osmotic stress. FYPO_relaxed.owl FYPO:0001023 biolink:NamedThing normal growth on cisplatin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cisplatin. FYPO_relaxed.owl FYPO:0001030 biolink:NamedThing normal growth on dithiothreitol A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing dithiothreitol. FYPO_relaxed.owl FYPO:0001075 biolink:NamedThing normal growth on papulacandin B A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing papulacandin B. FYPO_relaxed.owl FYPO:0001099 biolink:NamedThing normal growth on CCCP A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing carbonyl cyanide m-chlorophenyl hydrazone (CCCP). FYPO_relaxed.owl FYPO:0001100 biolink:NamedThing normal growth on Gentian violet A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing Gentian violet (also known as crystal violet). FYPO_relaxed.owl FYPO:0001148 biolink:NamedThing normal growth on amiloride A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing amiloride. FYPO_relaxed.owl FYPO:0001149 biolink:NamedThing normal growth on methylamine A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing methylamine. FYPO_relaxed.owl FYPO:0001164 biolink:NamedThing normal growth on glucose carbon source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing glucose as the carbon source. FYPO_relaxed.owl FYPO:0001166 biolink:NamedThing normal growth on fructose carbon source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing fructose as the carbon source. FYPO_relaxed.owl FYPO:0001174 biolink:NamedThing normal growth on sucrose carbon source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing sucrose as the carbon source. FYPO_relaxed.owl FYPO:0001175 biolink:NamedThing normal growth on maltose carbon source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing maltose as the carbon source. FYPO_relaxed.owl FYPO:0001192 biolink:NamedThing normal growth on cell wall-degrading enzymes A cell phenotype observed in the vegetative growth phase of the life cycle in which vegetative cell growth is normal (i.e. indistinguishable from wild type) in a medium containing one or more enzymes that degrades cell wall polysaccharides. FYPO_relaxed.owl FYPO:0001236 biolink:NamedThing normal growth on cycloheximide A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cycloheximide. FYPO_relaxed.owl FYPO:0001237 biolink:NamedThing normal growth on cadmium A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cadmium ions. FYPO_relaxed.owl FYPO:0001238 biolink:NamedThing normal growth on staurosporine A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing staurosporine. FYPO_relaxed.owl FYPO:0001239 biolink:NamedThing normal growth on tert-butyl hydroperoxide A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tert-butyl hydroperoxide (t-BOOH, TBHP). FYPO_relaxed.owl FYPO:0001240 biolink:NamedThing normal growth on diamide A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide, also known as diamide. FYPO_relaxed.owl FYPO:0001241 biolink:NamedThing normal growth on anisomycin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing anisomycin. FYPO_relaxed.owl FYPO:0001409 biolink:NamedThing normal growth on glycerol carbon source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing glycerol as the carbon source. FYPO_relaxed.owl FYPO:0001420 biolink:NamedThing normal vegetative cell population growth rate A cell population phenotype in which a population of cells grow at the same rate as wild type in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001435 biolink:NamedThing normal growth on erythromycin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing erythromycin. FYPO_relaxed.owl FYPO:0001436 biolink:NamedThing normal growth on trichodermin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing trichodermin. FYPO_relaxed.owl FYPO:0001437 biolink:NamedThing normal growth on antimycin A A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing antimycin A. FYPO_relaxed.owl FYPO:0001438 biolink:NamedThing normal growth on tetracycline A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tetracycline. FYPO_relaxed.owl FYPO:0001439 biolink:NamedThing normal growth on chloramphenicol A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing chloramphenicol. FYPO_relaxed.owl FYPO:0001454 biolink:NamedThing normal growth during cellular response to freezing A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to freezing conditions. FYPO_relaxed.owl FYPO:0001470 biolink:NamedThing normal growth on tacrolimus A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tacrolimus. FYPO_relaxed.owl FYPO:0001500 biolink:NamedThing normal growth on cytochalasin B A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cytochalasin B. FYPO_relaxed.owl FYPO:0001522 biolink:NamedThing normal growth on caffeine A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing caffeine. FYPO_relaxed.owl FYPO:0001523 biolink:NamedThing normal growth on leptomycin B A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing leptomycin B. FYPO_relaxed.owl FYPO:0001526 biolink:NamedThing normal growth on L-thialysine A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing L-thialysine. FYPO_relaxed.owl FYPO:0001545 biolink:NamedThing normal growth on L-canavanine A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing L-canavanine. FYPO_relaxed.owl FYPO:0001578 biolink:NamedThing normal growth on dipeptide nitrogen source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing a dipeptide such as Leu-Ala as the nitrogen source. FYPO_relaxed.owl FYPO:0001579 biolink:NamedThing normal growth on tetrapeptide nitrogen source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing a tetrapeptide such as Leu-Ser-Lys-Leu as the nitrogen source. FYPO_relaxed.owl FYPO:0001580 biolink:NamedThing normal growth on leucine nitrogen source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing leucine as the nitrogen source. FYPO_relaxed.owl FYPO:0001582 biolink:NamedThing normal growth on glutathione A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing glutathione. FYPO_relaxed.owl FYPO:0001686 biolink:NamedThing normal growth on carbendazim A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing the tubulin poison carbendazim (mecarzole; MBC). FYPO_relaxed.owl FYPO:0001687 biolink:NamedThing normal growth on benomyl A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing benomyl. FYPO_relaxed.owl FYPO:0001688 biolink:NamedThing normal growth on brefeldin A A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing brefeldin A. FYPO_relaxed.owl FYPO:0001689 biolink:NamedThing normal growth on 4-nitroquinoline N-oxide A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing 4-nitroquinoline N-oxide. FYPO_relaxed.owl FYPO:0001690 biolink:NamedThing normal growth on camptothecin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing camptothecin. FYPO_relaxed.owl FYPO:0001691 biolink:NamedThing normal growth on paraquat A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing paraquat. FYPO_relaxed.owl FYPO:0001795 biolink:NamedThing normal growth on purvalanol A A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing purvalanol A. FYPO_relaxed.owl FYPO:0001820 biolink:NamedThing normal growth on lithium A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing lithium ions. FYPO_relaxed.owl FYPO:0001829 biolink:NamedThing normal growth on gluconate carbon source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing gluconate as the carbon source. FYPO_relaxed.owl FYPO:0001835 biolink:NamedThing normal growth on acidic medium A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium that is more acidic than standard fission yeast media (about 5.8). FYPO_relaxed.owl FYPO:0001918 biolink:NamedThing normal growth on trifluoperazine A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing trifluoperazine. FYPO_relaxed.owl FYPO:0001975 biolink:NamedThing normal growth on nocodazole A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing nocodazole. FYPO_relaxed.owl FYPO:0001988 biolink:NamedThing normal cell population growth at high pH A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) at a pH higher than that of standard S. pombe growth medium (abut 5.8). FYPO_relaxed.owl FYPO:0001990 biolink:NamedThing normal cell population growth at low pH A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) at a pH lower than that of standard S. pombe growth medium (abut 5.8). FYPO_relaxed.owl FYPO:0001995 biolink:NamedThing normal growth on polymyxin B A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing polymyxin B. FYPO_relaxed.owl FYPO:0002081 biolink:NamedThing normal growth on TPCK A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing N-tosyl-L-phenylalanyl chloromethyl ketone (TPCK). FYPO_relaxed.owl FYPO:0002141 biolink:NamedThing normal cell population growth at low temperature A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) at a low temperature. FYPO_relaxed.owl FYPO:0002161 biolink:NamedThing normal growth on Calcofluor White A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing Calcofluor White. FYPO_relaxed.owl FYPO:0002168 biolink:NamedThing normal growth on ethyl methanesulfonate A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing ethyl methanesulfonate. FYPO_relaxed.owl FYPO:0002238 biolink:NamedThing normal growth on cerulenin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cerulenin. FYPO_relaxed.owl FYPO:0002329 biolink:NamedThing normal growth on pravastatin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing pravastatin. FYPO_relaxed.owl FYPO:0002343 biolink:NamedThing normal growth on terbinafine A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing terbinafine. FYPO_relaxed.owl FYPO:0002618 biolink:NamedThing normal growth on valproic acid A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing valproic acid. FYPO_relaxed.owl FYPO:0002619 biolink:NamedThing normal growth on sodium butyrate A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sodium butyrate. FYPO_relaxed.owl FYPO:0002620 biolink:NamedThing normal growth on trichostatin A A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing trichostatin A. FYPO_relaxed.owl FYPO:0002637 biolink:NamedThing normal growth on hygromycin B A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing hygromycin B. FYPO_relaxed.owl FYPO:0002643 biolink:NamedThing normal growth on clotrimazole A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing clotrimazole. FYPO_relaxed.owl FYPO:0002672 biolink:NamedThing normal growth on rapamycin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing rapamycin. FYPO_relaxed.owl FYPO:0002673 biolink:NamedThing normal growth on torin1 A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing torin1. FYPO_relaxed.owl FYPO:0002690 biolink:NamedThing normal growth on cumene hydroperoxide A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cumene hydroperoxide. FYPO_relaxed.owl FYPO:0002691 biolink:NamedThing normal growth on menadione A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing menadione. FYPO_relaxed.owl FYPO:0002707 biolink:NamedThing normal growth on cordycepin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cordycepin. FYPO_relaxed.owl FYPO:0003023 biolink:NamedThing normal growth on EPC A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing ethyl N-phenylcarbamate (EPC). FYPO_relaxed.owl FYPO:0003183 biolink:NamedThing normal growth on phleomycin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing phleomycin. FYPO_relaxed.owl FYPO:0003272 biolink:NamedThing normal growth on sodium hypochlorite A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sodium hypochlorite. FYPO_relaxed.owl FYPO:0003273 biolink:NamedThing normal growth on nitrite A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing nitrite ions. FYPO_relaxed.owl FYPO:0003274 biolink:NamedThing normal growth on GSNO A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing S-nitrosoglutathione (GSNO). FYPO_relaxed.owl FYPO:0003295 biolink:NamedThing normal growth on amitrole A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing amitrole. FYPO_relaxed.owl FYPO:0003370 biolink:NamedThing normal growth on sodium fluoride A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sodium fluoride. FYPO_relaxed.owl FYPO:0003506 biolink:NamedThing normal growth on copper A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing copper ions. FYPO_relaxed.owl FYPO:0003507 biolink:NamedThing normal growth on zinc A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing zinc ions. FYPO_relaxed.owl FYPO:0003508 biolink:NamedThing normal growth on mercury A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mercury ions. FYPO_relaxed.owl FYPO:0003509 biolink:NamedThing normal growth on selenite ion A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing selenite ions. FYPO_relaxed.owl FYPO:0003510 biolink:NamedThing normal growth on silver ions A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing silver ions. FYPO_relaxed.owl FYPO:0003618 biolink:NamedThing normal growth on aculeacin A A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing aculeacin A. FYPO_relaxed.owl FYPO:0003680 biolink:NamedThing normal growth on epirubicin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing epirubicin. FYPO_relaxed.owl FYPO:0003706 biolink:NamedThing normal growth on K-252a A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing K-252a. FYPO_relaxed.owl FYPO:0003707 biolink:NamedThing normal growth on valinomycin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing valinomycin. FYPO_relaxed.owl FYPO:0003719 biolink:NamedThing normal growth on tributyltin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tributyltin. FYPO_relaxed.owl FYPO:0003721 biolink:NamedThing normal growth on G418 A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing G418. FYPO_relaxed.owl FYPO:0003731 biolink:NamedThing normal growth on galactose carbon source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing galactose as the carbon source. FYPO_relaxed.owl FYPO:0003804 biolink:NamedThing normal growth on non-fermentable carbon source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing one or more non-fermentable substance(s) as the only carbon source(s). FYPO_relaxed.owl FYPO:0003809 biolink:NamedThing normal growth on latrunculin A A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing latrunculin A. FYPO_relaxed.owl FYPO:0003849 biolink:NamedThing normal growth on fluconazole A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing fluconazole. FYPO_relaxed.owl FYPO:0003850 biolink:NamedThing normal growth on oligomycin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing an oligomycin antibiotic. FYPO_relaxed.owl FYPO:0003851 biolink:NamedThing normal growth on MTT A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide). FYPO_relaxed.owl FYPO:0003852 biolink:NamedThing normal growth on FR901464 A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing FR901464. FYPO_relaxed.owl FYPO:0003898 biolink:NamedThing normal growth on glycerol/ethanol carbon source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing glycerol and ethanol as the carbon sources. FYPO_relaxed.owl FYPO:0003906 biolink:NamedThing normal growth on bleomycin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing bleomycin. FYPO_relaxed.owl FYPO:0004078 biolink:NamedThing normal growth on cyclosporin A A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cyclosporin A. FYPO_relaxed.owl FYPO:0004182 biolink:NamedThing normal vegetative growth on papuamide B A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing papuamide B. FYPO_relaxed.owl FYPO:0004186 biolink:NamedThing normal vegetative growth on myriocin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing myriocin. FYPO_relaxed.owl FYPO:0004229 biolink:NamedThing normal growth during cellular response to ionizing radiation A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0004285 biolink:NamedThing normal growth on mitomycin C A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mitomycin C. FYPO_relaxed.owl FYPO:0004348 biolink:NamedThing normal growth on methylglyoxal A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing methylglyoxal. FYPO_relaxed.owl FYPO:0004368 biolink:NamedThing normal growth on arsenic A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing an arsenic-containing substance. FYPO_relaxed.owl FYPO:0004399 biolink:NamedThing normal growth on KT5720 A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing the protein kinase inhibitor KT5720. FYPO_relaxed.owl FYPO:0004400 biolink:NamedThing normal growth on KT5823 A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing the protein kinase inhibitor KT5823. FYPO_relaxed.owl FYPO:0004401 biolink:NamedThing normal growth on KT5926 A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing the protein kinase inhibitor KT5926. FYPO_relaxed.owl FYPO:0004404 biolink:NamedThing normal growth on JM216 A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing JM216 (also called satraplatin). FYPO_relaxed.owl FYPO:0004406 biolink:NamedThing normal growth on JM335 A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing JM335. FYPO_relaxed.owl FYPO:0004408 biolink:NamedThing normal growth on triplatin tetranitrate A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing triplatin tetranitrate (also called BBR 3464). FYPO_relaxed.owl FYPO:0004410 biolink:NamedThing normal growth on tetraplatin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tetraplatin. FYPO_relaxed.owl FYPO:0004411 biolink:NamedThing normal growth on oxaliplatin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing oxaliplatin. FYPO_relaxed.owl FYPO:0004675 biolink:NamedThing normal growth on dimethyl sulfoxide A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing dimethyl sulfoxide. FYPO_relaxed.owl FYPO:0004858 biolink:NamedThing normal growth on Congo Red A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing Congo Red. FYPO_relaxed.owl FYPO:0004892 biolink:NamedThing normal growth on echinocandin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing an echinocandin. FYPO_relaxed.owl FYPO:0004940 biolink:NamedThing normal growth on chloroacetaldehyde A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing chloroacetaldehyde. FYPO_relaxed.owl FYPO:0004969 biolink:NamedThing normal vegetative cell population growth during phosphate starvation A cell growth phenotype in which vegetative cell population growth is cell population growth is normal (i.e. indistinguishable from wild type) under conditions of phosphate starvation. FYPO_relaxed.owl FYPO:0005228 biolink:NamedThing normal growth on doxorubicin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing doxorubicin. FYPO_relaxed.owl FYPO:0005254 biolink:NamedThing normal growth on tamoxifen A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tamoxifen. FYPO_relaxed.owl FYPO:0005450 biolink:NamedThing normal growth on okadaic acid A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing okadaic acid. FYPO_relaxed.owl FYPO:0005517 biolink:NamedThing normal growth on 6-azauracil A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing 6-azauracil. FYPO_relaxed.owl FYPO:0005751 biolink:NamedThing normal growth on Zeocin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing Zeocin (phleomycin D1). FYPO_relaxed.owl FYPO:0005776 biolink:NamedThing normal growth on acetaldehyde A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing v. FYPO_relaxed.owl FYPO:0005884 biolink:NamedThing normal growth on myxothiazol A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing myxothiazol. FYPO_relaxed.owl FYPO:0005947 biolink:NamedThing normal growth on potassium chloride A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing potassium chloride. FYPO_relaxed.owl FYPO:0005970 biolink:NamedThing normal growth on magnesium chloride A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing magnesium chloride. FYPO_relaxed.owl FYPO:0006017 biolink:NamedThing normal growth on urea A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing urea. FYPO_relaxed.owl FYPO:0006150 biolink:NamedThing normal growth on etoposide A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing etoposide. FYPO_relaxed.owl FYPO:0006219 biolink:NamedThing normal cell population growth during potassium ion starvation A cell growth phenotype in which vegetative cell population growth is cell population growth is normal (i.e. indistinguishable from wild type) under conditions of potassium ion starvation. FYPO_relaxed.owl FYPO:0006348 biolink:NamedThing normal growth on mechlorethamine A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mechlorethamine. FYPO_relaxed.owl FYPO:0006679 biolink:NamedThing normal growth on chromium A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing chromium ions. FYPO_relaxed.owl FYPO:0006717 biolink:NamedThing normal growth on sodium chloride A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sodium chloride, usually at a higher level than in standard media. FYPO_relaxed.owl FYPO:0006785 biolink:NamedThing normal growth on cobalt A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cobalt ions. FYPO_relaxed.owl FYPO:0006786 biolink:NamedThing normal growth on manganese A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing manganese ions. FYPO_relaxed.owl FYPO:0006854 biolink:NamedThing normal growth on EGTA A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing EGTA. FYPO_relaxed.owl FYPO:0006910 biolink:NamedThing normal growth on vanoxerine A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing vanoxerine. FYPO_relaxed.owl FYPO:0006911 biolink:NamedThing normal growth on hexestrol A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing hexestrol. FYPO_relaxed.owl FYPO:0006912 biolink:NamedThing normal growth on clomiphene A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing clomiphene. FYPO_relaxed.owl FYPO:0006913 biolink:NamedThing normal growth on ketoconazole A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing ketoconazole. FYPO_relaxed.owl FYPO:0006914 biolink:NamedThing normal growth on terconazole A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing terconazole. FYPO_relaxed.owl FYPO:0007035 biolink:NamedThing normal growth on 5-fluorouracil A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing 5-fluorouracil. FYPO_relaxed.owl FYPO:0007036 biolink:NamedThing normal growth on phenylglyoxal A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing phenylglyoxal. FYPO_relaxed.owl FYPO:0007074 biolink:NamedThing normal growth on mycophenolic acid A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing mycophenolic acid. FYPO_relaxed.owl FYPO:0007098 biolink:NamedThing normal growth on vanadate A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing vanadate ions (VO4(3-)). FYPO_relaxed.owl FYPO:0007121 biolink:NamedThing normal growth on iron A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing iron ions. FYPO_relaxed.owl FYPO:0007149 biolink:NamedThing normal growth on N-methyl-N'-nitro-N-nitrosoguanidine A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). FYPO_relaxed.owl FYPO:0007188 biolink:NamedThing normal growth on sampangine A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing sampangine. FYPO_relaxed.owl FYPO:0007331 biolink:NamedThing normal growth on formaldehyde A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing formaldehyde. FYPO_relaxed.owl FYPO:0007346 biolink:NamedThing normal growth during cellular response to DNA damage A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0007557 biolink:NamedThing normal growth on tolnaftate A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tolnaftate. FYPO_relaxed.owl FYPO:0007558 biolink:NamedThing normal growth on econazole A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing econazole. FYPO_relaxed.owl FYPO:0007559 biolink:NamedThing normal growth on diethylstilbestrol A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing diethylstilbestrol. FYPO_relaxed.owl FYPO:0007813 biolink:NamedThing normal growth on stavudine A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing stavudine. FYPO_relaxed.owl FYPO:0008017 biolink:NamedThing normal growth on glutamate nitrogen source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing glutamate as the nitrogen source. FYPO_relaxed.owl FYPO:0008018 biolink:NamedThing normal growth on glutamine nitrogen source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing glutamine as the nitrogen source. FYPO_relaxed.owl FYPO:0008019 biolink:NamedThing normal growth on arginine nitrogen source A vegetative cell population growth phenotype in which cells grow normally (i.e. indistinguishably from wild type) in a medium containing arginine as the nitrogen source. FYPO_relaxed.owl FYPO:0009110 biolink:NamedThing normal vegetative cell population growth after short incubation in hydroxyurea A cell growth phenotype in which cell population growth is normal after short incubation in hydroxyurea. FYPO_relaxed.owl FYPO:0002059 biolink:NamedThing inviable cell population A cell population phenotype in which none of the cells in the population are viable. FYPO_relaxed.owl FYPO:0003927 biolink:NamedThing decreased population viability in presence of persistent double-strand breaks A cell population phenotype in which a smaller than normal proportion of cells in the population is viable when double-strand breaks in DNA are continually made (for example, by constitutive expression of a nuclease). FYPO_relaxed.owl FYPO:0004163 biolink:NamedThing increased viability upon glucose starvation A cell population phenotype in which a larger than normal proportion of cells in the population remains viable when cells the population are subject to glucose starvation. FYPO_relaxed.owl FYPO:0004344 biolink:NamedThing increased viability upon nitrogen starvation A cell population phenotype in which a larger than normal proportion of cells in the population remains viable when cells the population are subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0005283 biolink:NamedThing increased viability upon inositol starvation A cell population phenotype in which a larger than normal proportion of cells in the population remains viable when cells the population are subject to inositol starvation. FYPO_relaxed.owl FYPO:0007629 biolink:NamedThing normal viability during G0 A cell population phenotype in which a normal proportion of cells in the population remains viable during G0 phase. FYPO_relaxed.owl FYPO:0009007 biolink:NamedThing decreased vegetative cell population viability A vegetative cell population phenotype in which a lower than normal proportion of cells is viable. In High Throughput Phenotyping this is typically assessed using phloxine as a dye. FYPO_relaxed.owl FYPO:0009008 biolink:NamedThing increased vegetative cell population viability A vegetative cell population phenotype in which a larger than normal proportion of cells is viable. In High Throughput Phenotyping this is typically assessed using phloxine as a dye. FYPO_relaxed.owl FYPO:0000252 biolink:NamedThing increased spontaneous diploidization A cell phenotype observed in the vegetative growth phase of the life cycle in which heterothallic haploid cells spontaneously form cells with diploid DNA content at a higher frequency than normal. FYPO_relaxed.owl FYPO:0000340 biolink:NamedThing haploinsufficient A cell phenotype observed in the vegetative growth phase of the life cycle in which a single functional copy of a gene does not provide sufficient normal function in a diploid cell. FYPO_relaxed.owl FYPO:0000341 biolink:NamedThing haplosufficient A cell phenotype observed in the vegetative growth phase of the life cycle in which a single functional copy of a gene provides sufficient normal function in a diploid cell. FYPO_relaxed.owl FYPO:0000786 biolink:NamedThing increased plasmid loss A cell phenotype observed in the vegetative growth phase of the life cycle in which plasmids are lost at a higher frequency than normal. Plasmid loss occurs when one or both daughter cells do not inherit copies of a plasmid from the mother cell, and may result from failure of plasmid replication or segregation. FYPO_relaxed.owl FYPO:0001159 biolink:NamedThing increased cellular pH A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured intracellular pH is higher than normal. FYPO_relaxed.owl FYPO:0001171 biolink:NamedThing decreased cellular pH A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured intracellular pH is lower than normal. FYPO_relaxed.owl FYPO:0001311 biolink:NamedThing decreased plasmid loss A cell phenotype observed in the vegetative growth phase of the life cycle in which plasmids are lost at a lower frequency than normal. Plasmid loss occurs when one or both daughter cells do not inherit copies of a plasmid from the mother cell, and may result from failure of plasmid replication or segregation. FYPO_relaxed.owl FYPO:0001386 biolink:NamedThing increased haploidization A cell phenotype in which non-sporulating diploid cells become haploid, without undergoing meiosis, at a higher frequency than normal. FYPO_relaxed.owl FYPO:0002334 biolink:NamedThing haploproficient A cell phenotype observed in the vegetative growth phase of the life cycle in which a diploid cell with a single functional copy of a gene grows faster than a diploid with two (on no) functional copies. FYPO_relaxed.owl FYPO:0003756 biolink:NamedThing multiple mitotic spindles with abolished sister chromatid separation A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell has more than one mitotic spindle, and mitotic sister chromatid separation does not occur. FYPO_relaxed.owl FYPO:0003913 biolink:NamedThing decreased minichromosome loss during vegetative growth A cell phenotype in which minichromosomes are lost at a lower frequency than normal during the vegetative growth phase of the life cycle. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation. FYPO_relaxed.owl FYPO:0003926 biolink:NamedThing increased number of converged replication forks A cell phenotype in which a cell contains a larger number of sites where replication forks have converged than normal. Additional converged forks are usually detected at sites that are normally replicated unidirectionally. FYPO_relaxed.owl FYPO:0004288 biolink:NamedThing decreased GT repeat stability A cell phenotype in which the number of GT dinucleotide microsatellite repeats present in a sequence varies more than normal. FYPO_relaxed.owl FYPO:0004418 biolink:NamedThing cut cell with decreased poly(A)+ mRNA export from nucleus A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes septation despite abnormal chromosome segregation, and in which the export of polyadenylated mRNA from the nucleus is decreased. The daughter cells produced by septation are both inviable. Export of all polyadenylated mRNAs or a specific mRNA may be affected. FYPO_relaxed.owl FYPO:0004580 biolink:NamedThing increased number of plasmid catenanes A cell phenotype in which a cell contains a larger number plasmid catenanes than normal. Plasmid catenanes are structures formed by two or more copies of a circular plasmid DNA molecule catenated together. FYPO_relaxed.owl FYPO:0004593 biolink:NamedThing abnormal vegetative cell phenotype following normal mitosis A phenotype that shows detectable differences from normal at the level of an individual cell, when the cell is in the vegetative growth phase of the cell cycle, and after it has undergone a normal mitotic nuclear division and passed through the subsequent mitotic interphase. FYPO_relaxed.owl FYPO:0005361 biolink:NamedThing increased level of large-Y replication intermediates A cell phenotype in which the level of large Y-shaped DNA replication intermediates is greater than normal. Large Y-shaped intermediates are formed late in the passive replication of a DNA region by a replication fork moving from outside the region. FYPO_relaxed.owl FYPO:0005451 biolink:NamedThing decreased break-induced loss of heterozygosity A cell phenotype observed in the vegetative growth phase of the life cycle in which one of two different alleles of a gene is lost less frequently than normal after a double-strand break forms nearby. FYPO_relaxed.owl FYPO:0005452 biolink:NamedThing increased break-induced loss of heterozygosity A cell phenotype observed in the vegetative growth phase of the life cycle in which one of two different alleles of a gene is lost more frequently than normal after a double-strand break forms nearby. FYPO_relaxed.owl FYPO:0005581 biolink:NamedThing short glycerophospholipids A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains glycerophospholipids that have shorter fatty acid chain residues than normal. FYPO_relaxed.owl FYPO:0005583 biolink:NamedThing increased fatty acid saturation A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains higher levels of saturated fatty acids, and lower levels of unsaturated fatty acids, than normal. FYPO_relaxed.owl FYPO:0005620 biolink:NamedThing increased SUMO chain length A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains sumoylated proteins that have longer poly-SUMO chains than normal. FYPO_relaxed.owl FYPO:0005621 biolink:NamedThing increased topoisomerase-DNA adduct level A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains more adducts formed between a topoisomerase and DNA than normal. FYPO_relaxed.owl FYPO:0005977 biolink:NamedThing prion formation A cell phenotype observed in the vegetative growth phase of the life cycle in which a soluble protein forms prions, by refolding and assembling into highly ordered, self-propagating detergent- and protease-resistant polymers. Phenotypes associated with prions are inherited in a non-Mendelian manner. FYPO_relaxed.owl FYPO:0006254 biolink:NamedThing abnormal ribosome footprint size distribution A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of ribosomal footprint lengths in a cell differs from wild type. Ribosomal footprints are RNA fragments protected by the ribosome, and normally range from 28-31 nucleotides long. FYPO_relaxed.owl FYPO:0006438 biolink:NamedThing alkylation damage repair intermediates absent A cell phenotype in which DNA molecules corresponding to alkylation damage repair intermediates are absent from the cell during DNA replication. FYPO_relaxed.owl FYPO:0006439 biolink:NamedThing increased level of X-shaped replication intermediates A cell phenotype in which the level of X-shaped DNA replication intermediates is greater than normal. X-shaped intermediates may be formed by replication forks moving bidirectionally from outside the region, or by the increased formation or persistence of Holliday junctions or similar recombination intermediates. FYPO_relaxed.owl FYPO:0007368 biolink:NamedThing increased energy charge A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell's energy charge higher than normal. Energy charge is a measure of energy available to the cell, as reflected in the ATP-ADP-AMP balance and defined as (ATP + 1/2 ADP)/(AMP + ADP + ATP). FYPO_relaxed.owl FYPO:0007369 biolink:NamedThing altered cellular redox status A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell's redox status differs from normal, as measured by the ratios of reduced to oxidized forms of one or more metabolites (e.g. NAD+:NADH). FYPO_relaxed.owl FYPO:0007392 biolink:NamedThing increased loss of disomic chromosome 3 A cell phenotype in which that are aneuploid due to the presence of an extra copy of chromosome 3 lose the extra chromosome, producing haploid daughter cells, at a higher frequency than in otherwise wild-type cells. FYPO_relaxed.owl FYPO:0007909 biolink:NamedThing increased vacuolar pH A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured vacuolar pH is higher than normal. FYPO_relaxed.owl FYPO:0008012 biolink:NamedThing cell sensitive to mechanical stress A cell phenotype in which a vegetative cell dies at a level of mechanical stress that wild-type cells can normally withstand. FYPO_relaxed.owl FYPO:0000253 biolink:NamedThing increased HMG-CoA reductase activity A molecular function phenotype in which the observed rate of hydroxymethylglutaryl-CoA reductase (NADPH) activity is increased. FYPO_relaxed.owl FYPO:0000662 biolink:NamedThing increased catalytic activity A molecular function phenotype in which the observed rate of a specified catalytic activity is increased. FYPO_relaxed.owl FYPO:0000667 biolink:NamedThing increased peptidase activity A molecular function phenotype in which the observed rate of a peptidase activity is increased. FYPO_relaxed.owl FYPO:0000796 biolink:NamedThing increased glycerol dehydrogenase activity A molecular function phenotype in which the observed rate of glycerol dehydrogenase activity is increased. FYPO_relaxed.owl FYPO:0000919 biolink:NamedThing increased citrate (Si)-synthase activity A molecular function phenotype in which the observed rate of citrate (Si)-synthase activity is increased. FYPO_relaxed.owl FYPO:0000921 biolink:NamedThing increased aconitate hydratase activity A molecular function phenotype in which the observed rate of aconitate hydratase (also known as aconitase) activity is increased. FYPO_relaxed.owl FYPO:0000923 biolink:NamedThing increased isocitrate dehydrogenase (NAD+) activity A molecular function phenotype in which the observed rate of isocitrate dehydrogenase (NAD+) activity is increased. FYPO_relaxed.owl FYPO:0001089 biolink:NamedThing increased glucosyltransferase activity A molecular function phenotype in which the observed rate of a glucosyltransferase activity is increased. FYPO_relaxed.owl FYPO:0001308 biolink:NamedThing increased long-chain fatty acid-CoA ligase activity A molecular function phenotype in which the observed rate of long-chain fatty acid-CoA ligase activity is increased. FYPO_relaxed.owl FYPO:0001478 biolink:NamedThing increased guanosine-diphosphatase activity A molecular function phenotype in which the observed rate of guanosine-diphosphatase activity is increased. FYPO_relaxed.owl FYPO:0001675 biolink:NamedThing increased L-aminoadipate-semialdehyde dehydrogenase activity A molecular function phenotype in which the observed rate of L-aminoadipate-semialdehyde dehydrogenase activity is increased. FYPO_relaxed.owl FYPO:0001751 biolink:NamedThing increased homocitrate synthase activity A molecular function phenotype in which the observed rate of homocitrate synthase activity is increased. FYPO_relaxed.owl FYPO:0001833 biolink:NamedThing increased phosphoglycerate mutase activity A molecular function phenotype in which the observed rate of phosphoglycerate mutase activity is increased. FYPO_relaxed.owl FYPO:0001842 biolink:NamedThing increased adenylyl cyclase activity A molecular function phenotype in which the observed rate of adenylyl cyclase activity is increased. FYPO_relaxed.owl FYPO:0001858 biolink:NamedThing increased fatty acid synthase activity A molecular function phenotype in which the observed rate of fatty acid synthase activity is increased. FYPO_relaxed.owl FYPO:0001999 biolink:NamedThing increased nucleoside diphosphate kinase activity A molecular function phenotype in which the observed rate of nucleoside diphosphate kinase activity is increased. FYPO_relaxed.owl FYPO:0002270 biolink:NamedThing increased glutamate-ammonia ligase activity A molecular function phenotype in which the observed rate of glutamate-ammonia ligase activity is increased. FYPO_relaxed.owl FYPO:0002524 biolink:NamedThing increased NADPH-hemoprotein reductase activity A molecular function phenotype in which the observed rate of NADPH-hemoprotein reductase activity is increased. FYPO_relaxed.owl FYPO:0002698 biolink:NamedThing increased methylenetetrahydrofolate reductase (NADPH) activity A molecular function phenotype in which the observed rate of methylenetetrahydrofolate reductase (NADPH) activity is increased. FYPO_relaxed.owl FYPO:0002700 biolink:NamedThing increased protein kinase activity A molecular function phenotype in which the observed rate of a protein kinase activity is increased. FYPO_relaxed.owl FYPO:0002756 biolink:NamedThing increased cysteine synthase activity A molecular function phenotype in which the observed rate of cysteine synthase activity is increased. FYPO_relaxed.owl FYPO:0002972 biolink:NamedThing increased ubiquitin ligase activity A molecular function phenotype in which the observed rate of ubiquitin ligase activity is increased. FYPO_relaxed.owl FYPO:0003112 biolink:NamedThing increased ubiquitinyl hydrolase activity A molecular function phenotype in which the observed rate of ubiquitinyl hydrolase activity is increased. FYPO_relaxed.owl FYPO:0003148 biolink:NamedThing increased UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity A molecular function phenotype in which the observed rate of UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity is increased. FYPO_relaxed.owl FYPO:0003285 biolink:NamedThing decreased alpha,alpha-trehalase activity during cellular response to nutrient A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is lower than normal during a cellular response to nutrient. FYPO_relaxed.owl FYPO:0003386 biolink:NamedThing increased superoxide dismutase activity A molecular function phenotype in which the observed rate of superoxide dismutase activity is increased. FYPO_relaxed.owl FYPO:0003419 biolink:NamedThing increased malate dehydrogenase (decarboxylating) (NAD+) activity A molecular function phenotype in which the observed rate of malate dehydrogenase (decarboxylating) (NAD+) activity is increased. FYPO_relaxed.owl FYPO:0003435 biolink:NamedThing increased ornithine carbamoyltransferase activity A molecular function phenotype in which the observed rate of ornithine carbamoyltransferase activity is increased. FYPO_relaxed.owl FYPO:0003497 biolink:NamedThing increased azetidine-2-carboxylic acid acetyltransferase activity A molecular function phenotype in which the observed rate of azetidine-2-carboxylic acid acetyltransferase activity is increased. FYPO_relaxed.owl FYPO:0003641 biolink:NamedThing increased adenylate kinase activity A molecular function phenotype in which the observed rate of adenylate kinase activity is increased. FYPO_relaxed.owl FYPO:0003725 biolink:NamedThing increased bis(5'-adenosyl)-hexaphosphatase activity A molecular function phenotype in which the observed rate of bis(5'-adenosyl)-hexaphosphatase activity is increased. FYPO_relaxed.owl FYPO:0003944 biolink:NamedThing increased thioredoxin peroxidase activity A molecular function phenotype in which the observed rate of thioredoxin peroxidase activity is increased. FYPO_relaxed.owl FYPO:0003960 biolink:NamedThing increased diacylglycerol O-acyltransferase activity A molecular function phenotype in which the observed rate of diacylglycerol O-acyltransferase activity is increased. FYPO_relaxed.owl FYPO:0003965 biolink:NamedThing increased glutathione disulfide oxidoreductase activity A molecular function phenotype in which the observed rate of a glutathione disulfide oxidoreductase activity is increased. FYPO_relaxed.owl FYPO:0003981 biolink:NamedThing increased glutathione transferase activity A molecular function phenotype in which the observed rate of glutathione transferase activity is increased. FYPO_relaxed.owl FYPO:0003983 biolink:NamedThing increased disulfide oxidoreductase activity A molecular function phenotype in which the observed rate of disulfide oxidoreductase activity is increased. FYPO_relaxed.owl FYPO:0003998 biolink:NamedThing increased DNA primase activity A molecular function phenotype in which the observed rate of DNA primase activity is increased. FYPO_relaxed.owl FYPO:0003999 biolink:NamedThing increased glutathione synthase activity A molecular function phenotype in which the observed rate of glutathione synthase activity is increased. FYPO_relaxed.owl FYPO:0004000 biolink:NamedThing increased glutamate-cysteine ligase activity A molecular function phenotype in which the observed rate of glutamate-cysteine ligase activity is increased. FYPO_relaxed.owl FYPO:0004036 biolink:NamedThing increased thioredoxin-disulfide reductase activity A molecular function phenotype in which the observed rate of thioredoxin-disulfide reductase activity is increased. FYPO_relaxed.owl FYPO:0004049 biolink:NamedThing increased glutathione peroxidase activity A molecular function phenotype in which the observed rate of glutathione peroxidase activity is increased. FYPO_relaxed.owl FYPO:0004131 biolink:NamedThing increased succinate dehydrogenase (ubiquinone) activity A molecular function phenotype in which the observed rate of succinate dehydrogenase (ubiquinone) activity is increased. FYPO_relaxed.owl FYPO:0004147 biolink:NamedThing increased pyridoxine:NADP 4-dehydrogenase activity A molecular function phenotype in which the observed rate of pyridoxine:NADP 4-dehydrogenase activity is increased. FYPO_relaxed.owl FYPO:0004415 biolink:NamedThing increased phosphatase activity A molecular function phenotype in which the observed rate of a phosphatase activity is increased. FYPO_relaxed.owl FYPO:0004564 biolink:NamedThing increased alpha-galactosidase activity A molecular function phenotype in which the observed rate of alpha-galactosidase activity is increased. FYPO_relaxed.owl FYPO:0004645 biolink:NamedThing increased bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity A molecular function phenotype in which the observed rate of bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity is increased. FYPO_relaxed.owl FYPO:0004857 biolink:NamedThing increased endo-1,6-beta-glucosidase activity A molecular function phenotype in which the observed rate of glucan endo-1,6-beta-glucosidase activity is increased. FYPO_relaxed.owl FYPO:0005175 biolink:NamedThing increased catalase activity A molecular function phenotype in which the observed rate of catalase activity is increased. FYPO_relaxed.owl FYPO:0005176 biolink:NamedThing increased ferric-chelate reductase activity A molecular function phenotype in which the observed rate of ferric-chelate reductase activity is increased. FYPO_relaxed.owl FYPO:0005724 biolink:NamedThing increased protein methyltransferase activity A molecular function phenotype in which the observed rate of protein methyltransferase activity is increased. FYPO_relaxed.owl FYPO:0006493 biolink:NamedThing increased chitin synthase activity A molecular function phenotype in which the observed rate of chitin synthase activity is increased. FYPO_relaxed.owl FYPO:0006652 biolink:NamedThing increased DNA/DNA annealing activity A molecular function phenotype in which the observed rate of a DNA/DNA annealing activity is increased. FYPO_relaxed.owl FYPO:0006894 biolink:NamedThing increased inositol hexakisphosphate kinase activity A molecular function phenotype in which the observed rate of inositol hexakisphosphate kinase activity is increased. FYPO_relaxed.owl FYPO:0007143 biolink:NamedThing increased 5'-deoxyribonuclease (pyrimidine dimer) activity A molecular function phenotype in which the observed rate of 5'-deoxyribonuclease (pyrimidine dimer) activity is increased. FYPO_relaxed.owl FYPO:0007364 biolink:NamedThing increased pyruvate kinase activity A molecular function phenotype in which the observed rate of pyruvate kinase activity is increased. FYPO_relaxed.owl FYPO:0007456 biolink:NamedThing increased 3' overhang single-stranded DNA endodeoxyribonuclease activity A molecular function phenotype in which the observed rate of 3' overhang single-stranded DNA endodeoxyribonuclease activity is increased. FYPO_relaxed.owl FYPO:0007674 biolink:NamedThing increased invertase activity A molecular function phenotype in which the observed rate of invertase activity (beta-fructofuranosidase activity) is increased. FYPO_relaxed.owl FYPO:0007840 biolink:NamedThing increased peptide alpha-N-acetyltransferase activity A molecular function phenotype in which the observed rate of peptide alpha-N-acetyltransferase activity is increased. FYPO_relaxed.owl FYPO:0008054 biolink:NamedThing decreased homocitrate synthase inhibition by L-lysine A molecular function phenotype in which the observed rate of homocitrate synthase is increased, due to the absence of lysine inhibition. FYPO_relaxed.owl FYPO:0008217 biolink:NamedThing increased DNA N-glycosylase activity A molecular function phenotype in which the observed rate of DNA N-glycosylase activity is increased. FYPO_relaxed.owl FYPO:0008231 biolink:NamedThing increased lactate dehydrogenase activity A molecular function phenotype in which the observed rate of lactate dehydrogenase activity is increased. FYPO_relaxed.owl FYPO:0000254 biolink:NamedThing increased protein processing during vegetative growth A cellular metabolism phenotype observed in the vegetative growth phase of the life cycle in which the observed occurrence of protein processing is increased. FYPO_relaxed.owl FYPO:0001421 biolink:NamedThing abnormal protein processing during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein processing is abnormal. Protein processing is the cleavage of one or more bonds within a protein that leads to the formation of mature, fully functional protein. FYPO_relaxed.owl FYPO:0001422 biolink:NamedThing decreased protein processing during vegetative growth A cellular metabolism phenotype observed in the vegetative growth phase of the life cycle in which the observed occurrence of protein processing is decreased. FYPO_relaxed.owl FYPO:0001669 biolink:NamedThing abolished protein processing during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the protein processing does not occur. Processing of all proteins or of one or more specific proteins may be affected. Protein processing is any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. FYPO_relaxed.owl FYPO:0006442 biolink:NamedThing constitutively activated sterol regulatory element binding protein cleavage A cellular process phenotype in which the proteolytic processing of sterol regulatory element binding protein (SREBP) into its transcriptionally active form is activated continuously. Normally, SREBP is cleaved only in response to altered levels of one or more lipids. FYPO_relaxed.owl FYPO:0000255 biolink:NamedThing increased nuclear protein level during vegetative growth A cell phenotype in which the amount of protein measured in the cell nucleus is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0000849 biolink:NamedThing increased cytoplasmic protein level during vegetative growth A cell phenotype in which the amount of protein measured in the cytoplasm of a cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001102 biolink:NamedThing increased protein level during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hydrogen peroxide is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001255 biolink:NamedThing increased protein level during cellular response to oxygen A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to the level of oxygen is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001551 biolink:NamedThing increased protein level during cellular response to zinc ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to zinc ion starvation is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0002010 biolink:NamedThing increased level of iron ion starvation-induced proteins A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein encoded by genes normally induced during iron ion starvation measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002011 biolink:NamedThing increased level of hydrogen peroxide-induced proteins during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein encoded by genes normally induced by exposure to hydrogen peroxide measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002354 biolink:NamedThing increased level of heterochromatin-encoded proteins A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein encoded by heterochromatic genes that are normally silenced is higher than normal. FYPO_relaxed.owl FYPO:0002703 biolink:NamedThing increased protein level in autophagosome A cell phenotype in which the amount of protein measured in autophagosomes is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0002774 biolink:NamedThing increased level of ubiquitinated protein in cell during vegetative growth A cell phenotype in which the amount of ubiquitinated protein measured in the cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003152 biolink:NamedThing increased protein level during cellular response to heat A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to heat is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003248 biolink:NamedThing increased level of histone H3 at centromere inner repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H3 measured at centromere inner repeat regions is higher than normal. FYPO_relaxed.owl FYPO:0003504 biolink:NamedThing increased protein level in plasma membrane A cell phenotype in which the amount of protein measured in the plasma membrane is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003966 biolink:NamedThing increased protein level during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to salt stress is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004108 biolink:NamedThing increased protein level during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G1 phase of the mitotic cell cycle is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004157 biolink:NamedThing increased protein level during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during mitosis is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004180 biolink:NamedThing increased cellular protein aggregate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein present as aggregates of misfolded protein is greater than normal. FYPO_relaxed.owl FYPO:0004189 biolink:NamedThing increased protein level during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hydroxyurea is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004503 biolink:NamedThing increased cellular HMW ubiquitin conjugate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein having high molecular mass due to polyubiquitin conjugation is greater than normal. FYPO_relaxed.owl FYPO:0005333 biolink:NamedThing increased protein level during cellular response to methyl methanesulfonate A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to methyl methanesulfonate is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005619 biolink:NamedThing increased level of sumoylated protein in cell A cell phenotype in which the amount of sumoylated protein measured in the cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005629 biolink:NamedThing increased cellular HMW SUMO conjugate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein having high molecular mass due to polySUMO conjugation is greater than normal. FYPO_relaxed.owl FYPO:0005893 biolink:NamedThing increased protein level in chromatin A cell phenotype in which the amount of protein found associated with chromatin is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0006114 biolink:NamedThing increased protein level during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during S phase of the mitotic cell cycle is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0006291 biolink:NamedThing increased protein level during mitotic G2 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G2 phase of the mitotic cell cycle is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0006847 biolink:NamedThing increased total protein level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of protein measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006886 biolink:NamedThing increased protein level at mitotic spindle A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured at or associated with the mitotic spindle is greater than normal. FYPO_relaxed.owl FYPO:0007052 biolink:NamedThing increased protein level during stress response to zinc ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular stress response to zinc ions is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007462 biolink:NamedThing increased filamentous actin level A cell phenotype in which the amount of filamentous actin measured the cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. The total actin level (globular and filamentous actin) may be normal or abnormal. FYPO_relaxed.owl FYPO:0007911 biolink:NamedThing increased level of GTP-bound protein A cell phenotype in which the amount of GTP-bound protein measured in the cell is higher than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0000256 biolink:NamedThing mutator A cell phenotype observed in the vegetative growth phase of the life cycle in which mutations occur at a higher frequency than normal. FYPO_relaxed.owl FYPO:0007432 biolink:NamedThing decreased transversion frequency A cell phenotype observed in the vegetative growth phase of the life cycle in which transversion mutations occur at a lower frequency than normal. FYPO_relaxed.owl FYPO:0000260 biolink:NamedThing abnormal G1/S phase transcription A gene expression phenotype in which regulation of transcription during the G1/S phase of the cell cycle is abnormal. FYPO_relaxed.owl FYPO:0001335 biolink:NamedThing transcription regulation phenotype during vegetative growth A gene expression phenotype that affects the regulation of DNA-dependent transcription in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000781 biolink:NamedThing decreased transcription during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0001865 biolink:NamedThing normal negative regulation of transcription by glucose A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by glucose (glucose repression) is normal. Transcription of specific genes is repressed in the presence of glucose, as in wild type. FYPO_relaxed.owl FYPO:0004527 biolink:NamedThing abnormal regulation of transcription during vegetative growth A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which any process of regulation of transcription is abnormal. FYPO_relaxed.owl FYPO:0000262 biolink:NamedThing abnormal cellular response to reactive oxygen species during G0 A cell phenotype in which cells do not respond normally to reactive oxygen species, resulting in accumulation of oxidative damage including DNA damage, during G0 phase. FYPO_relaxed.owl FYPO:0005044 biolink:NamedThing translation regulation phenotype during vegetative growth A gene expression phenotype that affects the regulation of translation in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000265 biolink:NamedThing sensitive to DNA damage A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to DNA damage. FYPO_relaxed.owl FYPO:0000267 biolink:NamedThing sensitive to ionizing radiation during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ionizing radiation. FYPO_relaxed.owl FYPO:0000268 biolink:NamedThing sensitive to UV during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ultraviolet light. FYPO_relaxed.owl FYPO:0000722 biolink:NamedThing sensitive to acidity A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to acidic pH. Cells stop growing (and may die) at a pH that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0000723 biolink:NamedThing sensitive to alkalinity A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to alkaline pH. Cells stop growing (and may die) at a pH that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001201 biolink:NamedThing sensitive to calcium ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to calcium ion starvation. FYPO_relaxed.owl FYPO:0001533 biolink:NamedThing sensitive to zinc starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to zinc starvation. FYPO_relaxed.owl FYPO:0001987 biolink:NamedThing sensitive to high pH A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to pH higher than that of standard S. pombe growth media (about 5.8). Cells stop growing (and may die) at a pH that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0001989 biolink:NamedThing sensitive to low pH A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to pH lower than that of standard S. pombe growth media (about 5.8). Cells stop growing (and may die) at a pH that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002015 biolink:NamedThing sensitive to iron ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to iron ion starvation. FYPO_relaxed.owl FYPO:0003146 biolink:NamedThing sensitive to hydrostatic pressure A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to hydrostatic pressure. FYPO_relaxed.owl FYPO:0005282 biolink:NamedThing sensitive to inositol starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to inositol starvation. FYPO_relaxed.owl FYPO:0006200 biolink:NamedThing sensitive to phosphate starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to phosphate starvation. FYPO_relaxed.owl FYPO:0006218 biolink:NamedThing sensitive to potassium ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to potassium ion starvation. FYPO_relaxed.owl FYPO:0006407 biolink:NamedThing sensitive to nitrosative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to nitrosative stress. FYPO_relaxed.owl FYPO:0002550 biolink:NamedThing sensitive to UV A cell phenotype in which cells show increased sensitivity to ultraviolet light. FYPO_relaxed.owl FYPO:0002551 biolink:NamedThing sensitive to UV during G0 A cell phenotype in which cells show increased sensitivity to ultraviolet light during G0 phase. FYPO_relaxed.owl FYPO:0000272 biolink:NamedThing abolished septum assembly A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell fails to form a septum. FYPO_relaxed.owl FYPO:0000567 biolink:NamedThing decreased duration of septum assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of septum assembly is shorter than normal. FYPO_relaxed.owl FYPO:0000639 biolink:NamedThing delayed onset of septum assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septum assembly begins later than normal. FYPO_relaxed.owl FYPO:0000651 biolink:NamedThing increased duration of septum assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of septum assembly is longer than normal. FYPO_relaxed.owl FYPO:0003202 biolink:NamedThing actomyosin contractile ring contraction uncoupled from septum assembly A cell phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction is not spatially and temporally coupled to division septum assembly as in wild type. The edges of the growing septum and the plasma membrane do not remain in contact, and septum assembly may be slower than ring contraction. FYPO_relaxed.owl FYPO:0003211 biolink:NamedThing abnormal secondary cell septum biogenesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which secondary cell septum biogenesis is abnormal. Secondary cell septum biogenesis results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of the secondary cell septum during cytokinesis. FYPO_relaxed.owl FYPO:0003890 biolink:NamedThing abnormal primary cell septum biogenesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum biogenesis is abnormal. Primary cell septum biogenesis results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of the primary cell septum during cytokinesis. FYPO_relaxed.owl FYPO:0000273 biolink:NamedThing centromeric outer repeat transcripts absent An RNA metabolism phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere outer repeat region are absent. FYPO_relaxed.owl FYPO:0003094 biolink:NamedThing decreased centromeric outer repeat transcript level A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere outer repeat region are present at lower levels than normal. FYPO_relaxed.owl FYPO:0004201 biolink:NamedThing decreased centromeric outer repeat transcript-derived siRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the centromere outer repeat region are present at lower levels than normal. FYPO_relaxed.owl FYPO:0004202 biolink:NamedThing decreased spliced cen-dg RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which spliced forms of RNAs transcribed from dg repeats in the centromere outer repeat region are present at lower levels than normal. FYPO_relaxed.owl FYPO:0000607 biolink:NamedThing abnormal mitotic M phase progression A cellular process phenotype in which progression through M phase of the mitotic cell cycle is abnormal. FYPO_relaxed.owl FYPO:0000608 biolink:NamedThing abnormal cell cycle arrest in mitotic M phase A cellular process phenotype in which progression through the mitotic cell cycle is arrested in M phase under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0000616 biolink:NamedThing abnormal mitotic anaphase progression A cellular process phenotype in which progression through mitotic anaphase is abnormal. FYPO_relaxed.owl FYPO:0000621 biolink:NamedThing delayed onset of mitotic metaphase A cellular process phenotype in which the onset of metaphase of mitosis begins later than normal. FYPO_relaxed.owl FYPO:0006490 biolink:NamedThing decreased duration of mitotic M phase A cell cycle phenotype in which the duration of M phase of the mitotic cell cycle is shorter than normal. FYPO_relaxed.owl FYPO:0000276 biolink:NamedThing monopolar mitotic spindle A physical cellular phenotype in which the mitotic spindle forms with microtubules emanating from only one pole. FYPO_relaxed.owl FYPO:0001574 biolink:NamedThing abnormal bipolar mitotic spindle A physical cellular phenotype in which the mitotic spindle has two poles but is otherwise structurally abnormal. FYPO_relaxed.owl FYPO:0002018 biolink:NamedThing mitotic spindle absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain a detectable mitotic spindle. FYPO_relaxed.owl FYPO:0003305 biolink:NamedThing separate mitotic half spindles present A spindle phenotype in which polar microtubules fail to interdigitate properly, and two partially or completely separated microtubule structures, usually V-shaped, each corresponding to one half of the spindle, are present. FYPO_relaxed.owl FYPO:0003754 biolink:NamedThing multiple mitotic spindles A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one mitotic spindle. FYPO_relaxed.owl FYPO:0003969 biolink:NamedThing mislocalized mitotic spindle A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a mitotic spindle in an abnormal location. The normal location is centered at the midpoint of, and parallel to, the long axis of the cell. FYPO_relaxed.owl FYPO:0004532 biolink:NamedThing abnormal cell cycle arrest in mitotic M phase with abnormal spindle A cellular process phenotype in which progression through the mitotic cell cycle is arrested in M phase under conditions where arrest does not normally occur, and the position or morphology of the mitotic spindle is abnormal. FYPO_relaxed.owl FYPO:0005960 biolink:NamedThing multipolar mitotic spindle A physical cellular phenotype in which a mitotic spindle forms with microtubules emanating from three or more poles. FYPO_relaxed.owl FYPO:0007388 biolink:NamedThing misoriented mitotic spindle A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle is assembled in an incorrect orientation. Normally, the spindle is parallel to the long axis of the cell. FYPO_relaxed.owl FYPO:0000278 biolink:NamedThing decreased cell population growth following spore germination A cell population phenotype in which cell population growth is decreased following spore germination, resulting in the formation of a smaller colony than normal in a given amount of time. FYPO_relaxed.owl FYPO:0000709 biolink:NamedThing decreased cell population growth during nitrogen starvation A cell growth phenotype in which cell population growth is decreased relative to normal under nitrogen starvation conditions, such as in nitrogen-deficient minimal medium. FYPO_relaxed.owl FYPO:0001235 biolink:NamedThing decreased extent of cell population growth A cellular process phenotype in which cell growth in a cell population occurs to a lower extent than normal, i.e. the population stops growing earlier than normal. FYPO_relaxed.owl FYPO:0000280 biolink:NamedThing sterile A cellular process phenotype in which conjugation does not occur. FYPO_relaxed.owl FYPO:0000412 biolink:NamedThing abnormal cell fusion during mating A cellular process phenotype in which plasma membrane fusion involved in cytogamy is abnormal. FYPO_relaxed.owl FYPO:0001864 biolink:NamedThing mating without glucose starvation A cellular process phenotype in which conjugation takes place in cells that are not subject to glucose starvation. FYPO_relaxed.owl FYPO:0003031 biolink:NamedThing mating without nitrogen starvation A cellular process phenotype in which conjugation takes place in cells that are not subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006010 biolink:NamedThing abolished shmoo contact with partner cell A cellular process phenotype in which a mating projection is assembled but does not meet a cell of the opposite mating type. FYPO_relaxed.owl FYPO:0006014 biolink:NamedThing promiscuous mating A cellular process phenotype in which one cell forms multiple mating projections that engage multiple partner cells. FYPO_relaxed.owl FYPO:0006669 biolink:NamedThing abnormal mating between three cells A cellular process phenotype in which one cell mates with two partners, leading to the fusion of three cells. The resulting zygote can then undergo sporulation to form an ascus containing more than four spores. FYPO_relaxed.owl FYPO:0007682 biolink:NamedThing abnormal cortical polarity patch dynamics during mating A cellular process phenotype in which assembly, exploratory movement, or disassembly of the Cdc42-containing cortical polarity patch is abnormal during mating. FYPO_relaxed.owl FYPO:0000469 biolink:NamedThing abolished mating type switching A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mating type switching does not occur. FYPO_relaxed.owl FYPO:0000531 biolink:NamedThing abolished mitotic cell cycle arrest in response to pheromone A cellular process phenotype in which mitotic cell cycle arrest in response to pheromone does not occur. FYPO_relaxed.owl FYPO:0000912 biolink:NamedThing abolished protein ubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the ubiquitination of one or more specific proteins, or of specific protein sites, does not occur. FYPO_relaxed.owl FYPO:0002393 biolink:NamedThing abolished protein acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of one or more specific proteins, or of specific protein sites, does not occur. FYPO_relaxed.owl FYPO:0002504 biolink:NamedThing abolished protein palmitoylation A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, does not occur. FYPO_relaxed.owl FYPO:0002565 biolink:NamedThing abolished histone methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation does not occur. All histone methylation may be affected, or methylation of specific sites on specific histones may be abolished. FYPO_relaxed.owl FYPO:0003080 biolink:NamedThing abolished genetic imprinting at mating-type locus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which genetic imprinting at the mating-type locus does not occur. FYPO_relaxed.owl FYPO:0003228 biolink:NamedThing abolished protein oxidation during cellular response to hydrogen peroxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the oxidation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0003728 biolink:NamedThing abolished protein galactosylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the galactosylation of one or more specific proteins, or of specific protein sites, does not occur. Protein galactosylation is the addition of a galactose residue to a protein amino acid. FYPO_relaxed.owl FYPO:0004392 biolink:NamedThing abolished positive regulation of DNA-directed DNA polymerase activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of DNA-directed DNA polymerase activity does not occur. FYPO_relaxed.owl FYPO:0004488 biolink:NamedThing abolished protein lysine methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of one or more lysine residues in specific proteins, or at specific protein sites, does not occur. FYPO_relaxed.owl FYPO:0004918 biolink:NamedThing abolished positive regulation of protein kinase activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of a protein kinase activity does not occur. FYPO_relaxed.owl FYPO:0005719 biolink:NamedThing abolished mitotic metaphase chromosome recapture A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromosome recapture does not occur during metaphase of mitosis. Chromosome recapture is the reattachment of chromosomes which have become detached from the spindle. FYPO_relaxed.owl FYPO:0005726 biolink:NamedThing abolished deactivation of mitotic spindle assembly checkpoint A cell cycle checkpoint phenotype in which deactivation of the mitotic spindle assembly checkpoint does not occur. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. FYPO_relaxed.owl FYPO:0005934 biolink:NamedThing abolished protein sumoylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the sumoylation of one or more specific proteins, or of specific protein sites, does not occur. FYPO_relaxed.owl FYPO:0006123 biolink:NamedThing abolished asymmetric protein arginine dimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine in one or more specific proteins, or of specific protein sites, does not occur. FYPO_relaxed.owl FYPO:0006375 biolink:NamedThing abolished protein processing during nitrogen starvation A cell phenotype in which the protein processing does not occur when the cell is subject to nitrogen starvation. Processing of all proteins or of one or more specific proteins may be affected. Protein processing is any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. FYPO_relaxed.owl FYPO:0006572 biolink:NamedThing abolished protein degradation during cellular response to pheromone A cellular process phenotype in which protein degradation does not occur during a cellular response to a pheromone. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0006869 biolink:NamedThing abolished histone H3-K36 methylation A cellular process phenotype in which methylation of lysine at position 36 of histone H3 does not occur. FYPO_relaxed.owl FYPO:0007361 biolink:NamedThing abolished positive regulation of ATPase activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of an ATPase activity does not occur. FYPO_relaxed.owl FYPO:0007789 biolink:NamedThing abolished hyphal growth A phenotype in which hyphal growth does not occur. FYPO_relaxed.owl FYPO:0000281 biolink:NamedThing small vacuoles present in increased numbers during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more, but smaller, vacuoles than normal. FYPO_relaxed.owl FYPO:0000952 biolink:NamedThing vacuoles present in increased numbers during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more vacuoles than normal. FYPO_relaxed.owl FYPO:0002258 biolink:NamedThing small vacuoles present in increased numbers A cell phenotype in which a cell contains more, but smaller, vacuoles than normal. FYPO_relaxed.owl FYPO:0001003 biolink:NamedThing small vacuoles present in increased numbers during nitrogen starvation A cell phenotype in which a cell contains more, but smaller, vacuoles than normal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0002791 biolink:NamedThing small vacuoles present in increased numbers during stationary phase A cell phenotype in which a cell contains more, but smaller, vacuoles than normal when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0002792 biolink:NamedThing small vacuoles present in increased numbers during cellular hypotonic response A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more, but smaller, vacuoles than normal during a cellular response to a hypotonic environment. FYPO_relaxed.owl FYPO:0000284 biolink:NamedThing large and small daughter nuclei, with unequal mitotic sister chromatid segregation A mitosis phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes unequal mitotic sister chromatid segregation, and as a result the nucleus divides unequally to produce one daughter nucleus that is larger than the other. FYPO_relaxed.owl FYPO:0006715 biolink:NamedThing large and small daughter nuclei A mitosis phenotype observed in the vegetative growth phase of the life cycle in which the nucleus divides unequally to produce one daughter nucleus that is larger than the other. FYPO_relaxed.owl FYPO:0006716 biolink:NamedThing large and small daughter nuclei, with unequal nuclear envelope distribution A mitosis phenotype observed in the vegetative growth phase of the life cycle in which chromosomes segregate equally (i.e. normally), but the nuclear envelope is not distributed equally between daughter nuclei. As a result, the nucleus divides unequally to produce one daughter nucleus that is larger than the other. FYPO_relaxed.owl FYPO:0000286 biolink:NamedThing sensitive to manganese depletion A cell population phenotype observed in the vegetative growth phase of the life cycle in which a population of cells grow poorly in medium that has a low concentration of manganese (Mn2+). FYPO_relaxed.owl FYPO:0001234 biolink:NamedThing slow vegetative cell population growth A cell population phenotype in which vegetative cell population growth is slower than normal. FYPO_relaxed.owl FYPO:0000291 biolink:NamedThing translation phenotype A cellular process phenotype that affects translation. FYPO_relaxed.owl FYPO:0001980 biolink:NamedThing normal RNA processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA processing is normal (i.e. indistinguishable from wild type). RNA processing is the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. FYPO_relaxed.owl FYPO:0004847 biolink:NamedThing transcription phenotype A cellular process phenotype that affects DNA-dependent transcription. FYPO_relaxed.owl FYPO:0000290 biolink:NamedThing transcription phenotype during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle that affects DNA-dependent transcription. FYPO_relaxed.owl FYPO:0002882 biolink:NamedThing normal transcription A cellular process phenotype in which transcription occurs to is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0000859 biolink:NamedThing normal metabolic process during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a cellular metabolic process is normal (i.e. indistinguishable from wild type). A metabolic process is any set of chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. FYPO_relaxed.owl FYPO:0001347 biolink:NamedThing nucleic acid metabolism phenotype during vegetative growth A cellular process phenotype that affects any nucleic acid metabolic process in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0002009 biolink:NamedThing decreased oxygen consumption during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of oxygen consumed by cells in a given time is lower than in wild type. FYPO_relaxed.owl FYPO:0003455 biolink:NamedThing decreased arginine catabolic process to proline A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of the breakdown of arginine into other compounds, including proline, is decreased. FYPO_relaxed.owl FYPO:0003933 biolink:NamedThing decreased nuclear 5'-3' exonucleolytic mRNA catabolic process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an exonucleolytic RNA catabolic process that proceeds in the 5' to 3' direction to degrade mRNA encoded in the nucleus is decreased. FYPO_relaxed.owl FYPO:0003954 biolink:NamedThing decreased triglyceride biosynthetic process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which triglyceride biosynthesis is decreased. FYPO_relaxed.owl FYPO:0003955 biolink:NamedThing increased triglyceride biosynthetic process A cellular metabolism phenotype observed in the vegetative growth phase of the life cycle in which triglyceride biosynthesis is increased. FYPO_relaxed.owl FYPO:0004166 biolink:NamedThing increased oxygen consumption during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of oxygen consumed by cells in a given time is higher than in wild type. FYPO_relaxed.owl FYPO:0008274 biolink:NamedThing decreased glutamate biosynthesis A metabolism phenotype observed in the vegetative growth phase of the life cycle in which glutamate biosynthesis is abnormal. FYPO_relaxed.owl FYPO:0000294 biolink:NamedThing RNA metabolism phenotype A cellular process phenotype that affects any RNA metabolic process. FYPO_relaxed.owl FYPO:0000295 biolink:NamedThing cytoskeleton organization phenotype A cellular process phenotype that affects cytoskeleton organization. Cytoskeleton organization results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. FYPO_relaxed.owl FYPO:0006003 biolink:NamedThing normal cellular component organization A cellular process phenotype in which any process of cellular component organization at the cellular level is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000296 biolink:NamedThing actin cytoskeleton organization phenotype A cellular process phenotype that affects the organization of the actin cytoskeleton. Actin cytoskeleton organization results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and associated proteins. FYPO_relaxed.owl FYPO:0000307 biolink:NamedThing inviable small spore A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and is smaller than normal. An inviable spore does not germinate. FYPO_relaxed.owl FYPO:0000309 biolink:NamedThing inviable spore with abnormal morphology A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and has an abnormal morphology (i.e. size, shape, or structure). An inviable spore does not germinate. FYPO_relaxed.owl FYPO:0002207 biolink:NamedThing inviable swollen spore A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. An inviable spore does not germinate. FYPO_relaxed.owl FYPO:0000346 biolink:NamedThing small spores A cell morphology phenotype in which spores have an abnormally low volume. FYPO_relaxed.owl FYPO:0000348 biolink:NamedThing abnormal spore morphology A cell phenotype characterized by altered spore morphology, i.e. the size, shape, or structure of the spore is abnormal. FYPO_relaxed.owl FYPO:0000347 biolink:NamedThing swollen spore A cell morphology phenotype in which a spore has a larger volume than normal. In a swollen cell, both length and diameter are greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0000944 biolink:NamedThing inviable spore with normal morphology A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and has a normal morphology (i.e. size, shape, or structure). An inviable spore does not germinate. FYPO_relaxed.owl FYPO:0002489 biolink:NamedThing spore lysis An inviable phenotype in which a spore lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised. FYPO_relaxed.owl FYPO:0007391 biolink:NamedThing inviable aneuploid spore A viability phenotype in which an aneuploid spore is unable to survive under conditions in which wild type spores survive. An inviable spore does not germinate. FYPO_relaxed.owl FYPO:0000310 biolink:NamedThing inviable after spore germination, without cell division, with normal germ tube morphology A phenotype in which a spore germinates to produce a normal germ tube, but does not go on to form a viable dividing cell. FYPO_relaxed.owl FYPO:0001991 biolink:NamedThing inviable after spore germination, without cell division A phenotype in which a spore germinates to produce a cell that dies without completing cell division. FYPO_relaxed.owl FYPO:0000313 biolink:NamedThing inviable after spore germination, without cell division, with abnormal germ tube morphology A phenotype in which a spore germinates to produce a germ tube with abnormal morphology (i.e. size, shape, or structure), and does not go on to form a viable dividing cell. FYPO_relaxed.owl FYPO:0001924 biolink:NamedThing inviable after spore germination, without cell division, cell cycle arrest A phenotype in which a spore germinates to produce a cell that enters the cell cycle but then undergoes cell cycle arrest, and eventually dies without completing cell division. FYPO_relaxed.owl FYPO:0002423 biolink:NamedThing inviable after spore germination, without cell division, septated cells with abnormal cell shape A phenotype in which a spore germinates to produce an inviable cell that forms a septum but does not divide, and that has an abnormal shape. FYPO_relaxed.owl FYPO:0002762 biolink:NamedThing inviable after spore germination, without cell division, spheroid cell A phenotype in which a spore germinates to produce an inviable cell that does not divide, and that is shaped in the form of a spheroid. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. FYPO_relaxed.owl FYPO:0004113 biolink:NamedThing inviable after spore germination, without cell division, small cell A phenotype in which a spore germinates to produce an inviable cell that does not divide, and that is smaller than normal. FYPO_relaxed.owl FYPO:0004114 biolink:NamedThing inviable after spore germination, without cell division, abnormal septum morphology A phenotype in which a spore germinates to produce an inviable cell that does not divide, and that has a septum with abnormal size, shape, or structure. FYPO_relaxed.owl FYPO:0004116 biolink:NamedThing inviable after spore germination, without cell division, cell enlarged around nucleus A phenotype in which a spore germinates to produce an inviable cell that does not divide, and that has a diameter larger than normal only near the middle of the cell, around the nucleus. FYPO_relaxed.owl FYPO:0004117 biolink:NamedThing inviable after spore germination, without cell division, normal septum morphology A phenotype in which a spore germinates to produce an inviable cell that does not divide, and that has a septum with normal size, shape, or structure. FYPO_relaxed.owl FYPO:0004558 biolink:NamedThing inviable after spore germination, without cell division, with abnormal cell morphology and abnormal actin cortical patch localization A phenotype in which a spore germinates to produce an inviable cell that does not divide, has an abnormal morphology, and in which actin cortical patch localization is abnormal. FYPO_relaxed.owl FYPO:0004603 biolink:NamedThing inviable after spore germination, without cell division, elongated cell A phenotype in which a spore germinates to produce an inviable cell that does not divide and is elongated. FYPO_relaxed.owl FYPO:0005469 biolink:NamedThing inviable after spore germination, without cell division, lysed cell A phenotype in which a spore germinates to produce an inviable cell that does not divide, and eventually lyses. FYPO_relaxed.owl FYPO:0006211 biolink:NamedThing inviable after spore germination, before germ tube formation A phenotype in which a spore germinates but dies before forming a germ tube or dividing. Such spores exit dormancy and undergo isotropic swelling but the spore wall does not rupture and no germ tube emerges. FYPO_relaxed.owl FYPO:0000311 biolink:NamedThing inviable after spore germination with normal, unseptated germ tube morphology A phenotype in which a spore germinates to produce a normal germ tube, but does not septate or go on to form a viable dividing cell. FYPO_relaxed.owl FYPO:0000312 biolink:NamedThing inviable after spore germination with normal, septated germ tube morphology A phenotype in which a spore germinates to produce a normal germ tube, and undergoes septation, but does not go on to form a viable dividing cell. FYPO_relaxed.owl FYPO:0000314 biolink:NamedThing inviable after spore germination with elongated germ tube A phenotype in which a spore germinates to produce an elongated germ tube, and does not go on to give rise to a viable cell population. FYPO_relaxed.owl FYPO:0001054 biolink:NamedThing cut, elongated cell An inviable phenotype in which a cell enters mitosis when longer than wild type, and then septates to give rise to a cut phenotype. In a cut phenotype, a cell undergoes septation despite abnormal mitosis such that the septum physically divides the nucleus into two parts. FYPO_relaxed.owl FYPO:0001493 biolink:NamedThing inviable elongated multinucleate vegetative cell A cell morphology phenotype in which a vegetative cell is inviable, is elongated, and contains more than one nucleus apiece. FYPO_relaxed.owl FYPO:0001497 biolink:NamedThing inviable elongated cell with mitotic cell cycle arrest in interphase A cell morphology phenotype in which a vegetative cell is inviable and elongated, and progression through the mitotic cell cycle is arrested in interphase. The cell contains one nucleus and no septum. FYPO_relaxed.owl FYPO:0002066 biolink:NamedThing inviable elongated aseptate cell A cell phenotype in which a cell has no septum, is elongated, and is inviable. FYPO_relaxed.owl FYPO:0002242 biolink:NamedThing inviable elongated tapered vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell. FYPO_relaxed.owl FYPO:0002262 biolink:NamedThing inviable after spore germination, multiple cell divisions, elongated cell A phenotype in which a spore germinates to produce a cell that is elongated, and undergoes two or more rounds of cell division and then dies. FYPO_relaxed.owl FYPO:0002411 biolink:NamedThing inviable curved elongated vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0002889 biolink:NamedThing inviable elongated vegetative cell with abnormal septum A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, and contains one or more abnormal septa. FYPO_relaxed.owl FYPO:0003875 biolink:NamedThing inviable elongated cell with mitotic G2/M transition delay and cell cycle arrest in M phase A cell phenotype in which a cell is elongated and inviable, and prior to death the cell undergoes a mitotic G2/M transition that begins later than normal, followed by cell cycle arrest in M phase. FYPO_relaxed.owl FYPO:0004255 biolink:NamedThing inviable elongated mononucleate vegetative cell A cell phenotype in which a cell contains one nucleus, is elongated, and is inviable. FYPO_relaxed.owl FYPO:0004494 biolink:NamedThing inviable branched, swollen, elongated vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, branched, septated, and has a larger volume and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0004672 biolink:NamedThing inviable elongated vegetative cell with fragmented nucleus A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, and contains a nucleus that is broken into small fragments. FYPO_relaxed.owl FYPO:0002281 biolink:NamedThing inviable after spore germination with abnormal germ tube morphology A phenotype in which a spore germinates to produce a germ tube with abnormal size, shape, or structure. FYPO_relaxed.owl FYPO:0002379 biolink:NamedThing inviable after spore germination, without cell division, with elongated germ tube A phenotype in which a spore germinates to produce an elongated germ tube, but does not go on to form a viable dividing cell. FYPO_relaxed.owl FYPO:0002212 biolink:NamedThing inviable after spore germination, without cell division, with elongated, curved germ tube A phenotype in which a spore germinates to produce an elongated germ tube that is curved along the long axis, but does not go on to form a viable dividing cell. FYPO_relaxed.owl FYPO:0002294 biolink:NamedThing inviable after spore germination with elongated germ tube and cell lysis A phenotype in which a spore germinates to produce an elongated germ tube, but does not go on to form a viable dividing cell, and instead lyses. FYPO_relaxed.owl FYPO:0002515 biolink:NamedThing inviable after spore germination, without cell division, with branched, elongated germ tube A phenotype in which a spore germinates to produce an elongated, branched germ tube, but does not go on to form a viable dividing cell. FYPO_relaxed.owl FYPO:0002911 biolink:NamedThing inviable after spore germination, without cell division, with swollen elongated germ tube A phenotype in which a spore germinates to produce an elongated germ tube that has a larger diameter and volume than normal, and does not go on to form a viable dividing cell. FYPO_relaxed.owl FYPO:0003313 biolink:NamedThing inviable after spore germination, without cell division, mononucleate cell with elongated germ tube A phenotype in which a spore germinates to produce an elongated germ tube, and in which the nucleus does not divide. The cell does not divide, and eventually dies. FYPO_relaxed.owl FYPO:0000320 biolink:NamedThing inviable after spore germination, single cell division, normal cell morphology A phenotype in which a spore germinates to produce a cell of normal morphology (i.e. size, shape, and structure) that undergoes a single round of cell division, and then dies. FYPO_relaxed.owl FYPO:0001124 biolink:NamedThing normal vegetative cell size A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has normal volume and dimensions. FYPO_relaxed.owl FYPO:0001125 biolink:NamedThing normal vegetative cell shape A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal shape. FYPO_relaxed.owl FYPO:0002177 biolink:NamedThing viable vegetative cell with normal cell morphology A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell has normal volume, dimensions and shape, and is viable. FYPO_relaxed.owl FYPO:0002850 biolink:NamedThing normal cell morphology during recovery from stationary phase A cell phenotype characterized by normal cell morphology (i.e. size, shape, and structure) when the cell population has been in stationary phase and is then placed in conditions that allow recovery. FYPO_relaxed.owl FYPO:0002280 biolink:NamedThing inviable after spore germination, single cell division A phenotype in which a spore germinates to produce a cell that undergoes a single round of cell division, and then dies. FYPO_relaxed.owl FYPO:0002420 biolink:NamedThing inviable after spore germination, single cell division, abnormal cell shape A phenotype in which a spore germinates to produce cell that has an abnormal shape and undergoes a single round of cell division. FYPO_relaxed.owl FYPO:0003842 biolink:NamedThing inviable following spore germination, single cell division, abolished mitotic sister chromatid separation A phenotype in which a spore germinates to produce a cell that undergoes a single round of cell division in which mitotic sister chromatid separation does not occur, and then dies. FYPO_relaxed.owl FYPO:0004493 biolink:NamedThing inviable after spore germination, single cell division, small cell A phenotype in which a spore germinates to produce a cell that undergoes a single round of cell division to produce daughter cells that are smaller than normal, which then die. FYPO_relaxed.owl FYPO:0000326 biolink:NamedThing abnormal mitotic sister chromatid biorientation A cellular process phenotype in which the stable attachment of sister chromatids to microtubules emanating from opposite poles of the mitotic spindle during metaphase plate congression is abnormal. FYPO_relaxed.owl FYPO:0004366 biolink:NamedThing syntelic kinetochore attachment during mitosis A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during a mitotic nuclear division results in the connection of both sister kinetochores to microtubules from the same spindle pole. FYPO_relaxed.owl FYPO:0004381 biolink:NamedThing merotelic kinetochore attachment during mitosis A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during a mitotic nuclear division results in the connection of a single kinetochore to both spindle poles. FYPO_relaxed.owl FYPO:0004382 biolink:NamedThing meroterically attached lagging mitotic chromosomes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a single kinetochore becomes attached to both spindle poles, and sister chromatids do not move towards the spindle poles at the same time during mitosis prior to completion of chromosome segregation. FYPO_relaxed.owl FYPO:0005411 biolink:NamedThing increased number of unattached kinetochores A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore results in a larger number of kinetochores remaining unattached than normal. FYPO_relaxed.owl FYPO:0006179 biolink:NamedThing abnormal lateral attachment of mitotic spindle microtubules to kinetochore A cellular process phenotype in which the lateral attachment of sister chromatids to mitotic spindle microtubules is abnormal. Normally, sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate). FYPO_relaxed.owl FYPO:0002275 biolink:NamedThing abnormal protein degradation A cellular process phenotype in which protein degradation is abnormal. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0002494 biolink:NamedThing abnormal protein modification A cellular process phenotype in which protein modification is abnormal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0000329 biolink:NamedThing abnormal protein modification during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification is abnormal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0002497 biolink:NamedThing abolished protein modification A cellular process phenotype in which protein modification does not occur. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0002498 biolink:NamedThing decreased protein modification A cellular process phenotype in which the occurrence of protein modification is decreased. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0002499 biolink:NamedThing increased protein modification A cellular process phenotype in which the occurrence of protein modification is increased. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0002503 biolink:NamedThing abnormal protein palmitoylation A cellular process phenotype in which the palmitoylation of one or more specific proteins is abnormal. FYPO_relaxed.owl FYPO:0002677 biolink:NamedThing abnormal protein phosphorylation A cellular process phenotype in which the phosphorylation of one or more specific proteins is abnormal. FYPO_relaxed.owl FYPO:0004426 biolink:NamedThing abnormal protein dephosphorylation A cellular process phenotype in which the dephosphorylation of one or more specific proteins is abnormal. FYPO_relaxed.owl FYPO:0006458 biolink:NamedThing abnormal histone modification A cellular process phenotype that affects histone modification. FYPO_relaxed.owl FYPO:0006459 biolink:NamedThing abnormal protein modification during meiotic cell cycle A cellular process phenotype in which protein modification is abnormal during the meiotic cell cycle. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0006977 biolink:NamedThing abnormal protein ubiquitination A cellular process phenotype in which the ubiquitination of one or more specific proteins, or of specific protein sites, is abnormal. FYPO_relaxed.owl FYPO:0000544 biolink:NamedThing abolished protein modification during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification does not occur. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0000545 biolink:NamedThing decreased protein modification during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein modification is decreased. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0000546 biolink:NamedThing delayed onset of protein modification during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification begins later than normal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0000548 biolink:NamedThing increased duration of protein modification during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein modification processes is longer than normal. All modifications may be affected, or only modifications of a certain type, or on specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0000775 biolink:NamedThing abnormal protein phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, is abnormal. FYPO_relaxed.owl FYPO:0000905 biolink:NamedThing abnormal protein ubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the ubiquitination of one or more specific proteins, or of specific protein sites, is abnormal. FYPO_relaxed.owl FYPO:0001910 biolink:NamedThing abnormal protein glycosylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the glycosylation of one or more specific proteins, or of specific protein sites, is abnormal. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid. FYPO_relaxed.owl FYPO:0002392 biolink:NamedThing abnormal protein acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of one or more specific proteins is abnormal. FYPO_relaxed.owl FYPO:0002506 biolink:NamedThing abnormal protein palmitoylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the palmitoylation of one or more specific proteins is abnormal. FYPO_relaxed.owl FYPO:0002777 biolink:NamedThing abnormal protein sumoylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the sumoylation of one or more specific proteins, or of specific protein sites, is abnormal. FYPO_relaxed.owl FYPO:0004002 biolink:NamedThing increased duration of protein phosphorylation during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is longer than normal during a cellular response to hydroxyurea. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0004326 biolink:NamedThing increased duration of protein phosphorylation during cellular response to methylglyoxal A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is longer than normal during a cellular response to methylglyoxal. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0005093 biolink:NamedThing decreased duration of protein phosphorylation during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is shorter than normal during a cellular response to hydroxyurea. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0005819 biolink:NamedThing abnormal protein neddylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the neddylation of one or more specific proteins, or of specific protein sites, is abnormal. FYPO_relaxed.owl FYPO:0005851 biolink:NamedThing abnormal protein biotinylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the biotinylation of one or more specific proteins is abnormal. FYPO_relaxed.owl FYPO:0006122 biolink:NamedThing abnormal protein methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of one or more specific proteins is abnormal. FYPO_relaxed.owl FYPO:0006157 biolink:NamedThing increased duration of protein oxidation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of oxidation of one or more specific proteins, or of specific protein sites is longer than normal. FYPO_relaxed.owl FYPO:0006229 biolink:NamedThing increased duration of protein phosphorylation during cellular response to phosphate starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is longer than normal during a cellular response to phosphate starvation. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0006718 biolink:NamedThing increased duration of protein phosphorylation during cellular response to osmotic stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is longer than normal during a cellular response to osmotic stress. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0006870 biolink:NamedThing abnormal histone methylation A cellular process phenotype in which histone methylation is abnormal. All histone methylation may be affected, or methylation of specific sites on specific histones may be altered. FYPO_relaxed.owl FYPO:0007470 biolink:NamedThing abnormal histone modification during G0 A cellular process phenotype that affects histone modification during G0 phase. FYPO_relaxed.owl FYPO:0000331 biolink:NamedThing decreased histone acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone acetylation occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0000332 biolink:NamedThing increased histone acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone acetylation occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0002361 biolink:NamedThing abnormal histone H3 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3 acetylation is abnormal. FYPO_relaxed.owl FYPO:0002364 biolink:NamedThing abnormal histone H4 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H4 acetylation is abnormal. FYPO_relaxed.owl FYPO:0002394 biolink:NamedThing decreased protein acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004487 biolink:NamedThing increased protein acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000398 biolink:NamedThing premature mitotic G1/S phase transition A cellular process phenotype in which progression through the G1/S transition of the mitotic cell cycle begins earlier than normal. FYPO_relaxed.owl FYPO:0002991 biolink:NamedThing premature mitotic G1/S phase transition during cellular response to hydrogen peroxide A cellular process phenotype in which progression through the G1/S transition of the mitotic cell cycle begins earlier than normal, during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0002992 biolink:NamedThing premature mitotic G1/S phase transition during cellular response to methyl methanesulfonate A cellular process phenotype in which progression through the G1/S transition of the mitotic cell cycle begins earlier than normal, during a cellular response to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0003548 biolink:NamedThing abolished mitotic G1/S phase transition following nitrogen starvation-induced G1 phase arrest A cell cycle phenotype in which the G1/S transition of the mitotic cell cycle does not occur after the cell has been arrested in G1 phase due to nitrogen starvation. The cell remains arrested in G1. FYPO_relaxed.owl FYPO:0006909 biolink:NamedThing mitotic G1/S phase transition at small cell size A cell cycle phenotype in which the G1/S transition of the mitotic cell cycle occurs at a smaller cell size than normal after the cell has been arrested in G1 phase due to nitrogen starvation. The cell remains arrested in G1. FYPO_relaxed.owl FYPO:0000602 biolink:NamedThing abnormal mitotic G1 phase progression A cellular process phenotype in which progression through the G1 phase of the mitotic cell cycle is abnormal. FYPO_relaxed.owl FYPO:0000603 biolink:NamedThing decreased duration of mitotic G1 phase A cellular process phenotype in which the duration of G1 phase of a mitotic cell cycle is shorter than normal. FYPO_relaxed.owl FYPO:0000828 biolink:NamedThing premature mitotic G1 phase entry A cellular process phenotype in which entry into the G1 phase of the mitotic cell cycle (exit from mitosis) begins earlier than normal. FYPO_relaxed.owl FYPO:0003130 biolink:NamedThing premature mitotic G1 phase entry during cellular response to ionizing radiation A cellular process phenotype in which entry into the G1 phase of the mitotic cell cycle (exit from mitosis) begins earlier than normal during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0000734 biolink:NamedThing abnormal meiotic spindle A physical cellular phenotype in which the structure of the meiotic spindle is abnormal. FYPO_relaxed.owl FYPO:0000339 biolink:NamedThing mislocalized septum during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a septum in an abnormal location. The normal location is at the midpoint of the long axis of the cell. The site of septum assembly is normally determined by the location of the actomyosin contractile ring. FYPO_relaxed.owl FYPO:0001390 biolink:NamedThing misoriented septum during vegetative growth A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that is not perpendicular to the long axis of the cell. FYPO_relaxed.owl FYPO:0002023 biolink:NamedThing abnormal septum morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the septum is abnormal. FYPO_relaxed.owl FYPO:0002456 biolink:NamedThing viable curved vegetative cell with abnormal septum A cell morphology phenotype in which a vegetatively growing cell is viable, is curved along the long axis, and contains one or more abnormal septa. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0003204 biolink:NamedThing secondary cell septum absent from cell during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain a detectable secondary cell septum. FYPO_relaxed.owl FYPO:0004293 biolink:NamedThing mislocalized septum A physical cellular phenotype in which a cell or hypha has a septum in an abnormal location. The normal location during yeast-form growth is at the midpoint of the long axis of the cell. FYPO_relaxed.owl FYPO:0004294 biolink:NamedThing mislocalized septum in stationary phase A cell phenotype in which a cell has a septum in an abnormal location when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0007801 biolink:NamedThing mislocalized hyphal septum A physical cellular phenotype in which a dividing cell at the growith end of a hypha has a septum in an abnormal location. Normally, the septum forms in the cytosol-enriched portion of the cell, displaced slightly off-center toward the portion of the cell occupied by the vacuole. FYPO_relaxed.owl FYPO:0000342 biolink:NamedThing decreased cellular respiration A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular respiration is decreased. FYPO_relaxed.owl FYPO:0000564 biolink:NamedThing decreased rate of cellular respiration A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of cellular respiration is decreased. FYPO_relaxed.owl FYPO:0000565 biolink:NamedThing increased cellular respiration A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular respiration is increased. FYPO_relaxed.owl FYPO:0003393 biolink:NamedThing abnormal respiratory electron transport A metabolism phenotype observed in the vegetative growth phase of the life cycle in which electron transport involved in cellular respiration is abnormal. FYPO_relaxed.owl FYPO:0000343 biolink:NamedThing increased concentration of hydrogen sulfide in growth medium A phenotype in which the concentration of hydrogen sulfide released into the growth medium by cells is higher than normal. FYPO_relaxed.owl FYPO:0000800 biolink:NamedThing increased concentration of substance in growth medium A phenotype in which the concentration of a substance released into the growth medium by cells is higher than normal. FYPO_relaxed.owl FYPO:0000803 biolink:NamedThing increased concentration of DHA in growth medium A phenotype in which the concentration of glycerone (also called 1,3-dihydroxypropan-2-one, dihydroxyacetone, or DHA) released into the growth medium by cells is higher than normal. FYPO_relaxed.owl FYPO:0000817 biolink:NamedThing increased concentration of pheromone in growth medium A phenotype in which the concentration of a peptide pheromone released into the growth medium by cells is higher than normal. FYPO_relaxed.owl FYPO:0002264 biolink:NamedThing increased concentration of polysaccharide in growth medium A phenotype in which the concentration of one or more polysaccharides released into the growth medium by cells is higher than normal. FYPO_relaxed.owl FYPO:0002671 biolink:NamedThing increased concentration of protein in growth medium A phenotype in which the concentration of one or more proteins released into the growth medium by cells is higher than normal. FYPO_relaxed.owl FYPO:0000344 biolink:NamedThing enlarged nucleus during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is larger than normal. FYPO_relaxed.owl FYPO:0000365 biolink:NamedThing small nucleus A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is smaller than normal. FYPO_relaxed.owl FYPO:0000769 biolink:NamedThing abnormal nuclear envelope morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the nuclear envelope is abnormal. FYPO_relaxed.owl FYPO:0001782 biolink:NamedThing constricted nucleus A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is constricted in the middle, resembling a figure 8. FYPO_relaxed.owl FYPO:0001919 biolink:NamedThing fragmented nucleus during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is broken into multiple small fragments that are smaller than a normal nucleus. FYPO_relaxed.owl FYPO:0004100 biolink:NamedThing inviable after spore germination, without cell division, elongated cell with abnormal nuclear morphology A phenotype in which a spore germinates to produce an inviable cell that does not divide, is elongated, and contains a nucleus with abnormal morphology. FYPO_relaxed.owl FYPO:0005347 biolink:NamedThing pointed nucleus during mitotic interphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus has a pointed shape during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0000999 biolink:NamedThing enlarged nucleus during nitrogen starvation A physical cellular phenotype in which the nucleus is larger than normal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006663 biolink:NamedThing elongated nucleus A physical cellular phenotype in which the nucleus is longer than normal. FYPO_relaxed.owl FYPO:0000675 biolink:NamedThing abnormal protein targeting during vegetative growth A transport phenotype observed in the vegetative growth phase of the life cycle in which protein targeting is abnormal. FYPO_relaxed.owl FYPO:0003446 biolink:NamedThing decreased SRP-dependent cotranslational protein targeting to membrane during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of SRP-dependent cotranslational protein targeting to the ER membrane is decreased. FYPO_relaxed.owl FYPO:0005830 biolink:NamedThing abnormal protein transport along microtubule during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules is abnormal. Transport of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005745 biolink:NamedThing abnormal protein export from nucleus A transport phenotype in which the export of protein from the nucleus is abnormal. Export of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005746 biolink:NamedThing decreased protein export from nucleus during glucose starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein export from nucleus is decreased when the cell is subject to glucose starvation. Export of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0000995 biolink:NamedThing abnormal cell morphology during nitrogen starvation A cell phenotype in which cell morphology (i.e. the size, shape, or structure of the cell) is altered when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0000349 biolink:NamedThing abnormal Golgi morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the Golgi apparatus is abnormal. FYPO_relaxed.owl FYPO:0000353 biolink:NamedThing abnormal endomembrane system morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the endomembrane system is abnormal. FYPO_relaxed.owl FYPO:0000354 biolink:NamedThing abnormal endoplasmic reticulum morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the endoplasmic reticulum is abnormal. FYPO_relaxed.owl FYPO:0007727 biolink:NamedThing abnormal late endosome morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of late endosomes is abnormal. FYPO_relaxed.owl FYPO:0000350 biolink:NamedThing abnormal actin cytoskeleton morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the actin cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0000352 biolink:NamedThing abnormal cytoskeleton morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0002398 biolink:NamedThing abnormal actin cytoskeleton during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, or morphology of all or part of the actin cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0001369 biolink:NamedThing mislocalized actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms an actomyosin contractile ring in an abnormal location. The normal location is at the midpoint of, and perpendicular to, the long axis of the cell. FYPO_relaxed.owl FYPO:0002028 biolink:NamedThing multiple actomyosin contractile rings present A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one actomyosin contractile ring. FYPO_relaxed.owl FYPO:0002435 biolink:NamedThing abnormal actin cables A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, or morphology of actin cables is abnormal. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts. FYPO_relaxed.owl FYPO:0003001 biolink:NamedThing actin filaments present in increased numbers A physical cellular phenotype in which cells contain more actin filaments than normal. FYPO_relaxed.owl FYPO:0003987 biolink:NamedThing abnormal actin cortical patch A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, or morphology of actin cortical patches is abnormal. FYPO_relaxed.owl FYPO:0004736 biolink:NamedThing abnormal actomyosin contractile ring A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the position, composition or morphology of the actomyosin contractile ring is abnormal. FYPO_relaxed.owl FYPO:0006304 biolink:NamedThing medial F-actin spot present A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which F-actin forms a large spot in the medial region of the cell, instead of assembling into a contractile ring. FYPO_relaxed.owl FYPO:0000351 biolink:NamedThing abnormal cell wall morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the fungal-type cell wall is abnormal. FYPO_relaxed.owl FYPO:0002627 biolink:NamedThing altered level of substance in cell wall during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cell wall differs from normal. FYPO_relaxed.owl FYPO:0002947 biolink:NamedThing abnormal cell wall morphology A physical cellular phenotype in which the size, shape, or structure of the fungal-type cell wall is abnormal. FYPO_relaxed.owl FYPO:0002948 biolink:NamedThing delaminated cell wall A physical cellular phenotype in which the fungal-type cell wall is delaminated, i.e. one or more of its layers peels off. FYPO_relaxed.owl FYPO:0003138 biolink:NamedThing abnormal ascospore wall morphology A physical cellular phenotype in which the size, shape, or structure of the ascospore wall is abnormal. FYPO_relaxed.owl FYPO:0003063 biolink:NamedThing abnormal cytoskeleton morphology A physical cellular phenotype in which the size, shape, or structure of the cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0002652 biolink:NamedThing excess intracellular endomembrane system present A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more intracellular endomembrane system structures than normal. The endomembrane system includes the endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope; in this phenotype, excess plasma membrane does not accumulate, but increased amounts of one or more internal intracellular endomembrane system structures may be present. FYPO_relaxed.owl FYPO:0000355 biolink:NamedThing normal endoplasmic reticulum morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the endoplasmic reticulum is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001314 biolink:NamedThing normal cell cortex morphology during vegetative growth A physical cellular phenotype in which the size, shape, and structure of the cell cortex are normal when the cell is in the vegetative growth phase of the life cycle. The cell cortex is the region of a cell that lies just beneath the plasma membrane. FYPO_relaxed.owl FYPO:0001380 biolink:NamedThing normal nuclear morphology during vegetative growth A physical cellular phenotype in which the size, shape, or structure of the nucleus is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001399 biolink:NamedThing normal mitotic spindle A physical cellular phenotype in which the mitotic spindle is normal (i.e. indistinguishable from wild type) with respect to structure, composition, location, and orientation. FYPO_relaxed.owl FYPO:0001905 biolink:NamedThing normal mitotic spindle microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the number, structure, and orientation of microtubules in the mitotic spindle are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001976 biolink:NamedThing normal cytoplasmic microtubules during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, and morphology of cytoplasmic microtubules is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002022 biolink:NamedThing normal actin cortical patch morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of actin cortical patches are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002487 biolink:NamedThing normal actin cable morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of actin cables are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003137 biolink:NamedThing normal mitotic spindle pole body A physical cellular phenotype in which the mitotic spindle pole bodies are normal (i.e. indistinguishable from wild type) with respect to structure, composition, location, and orientation. FYPO_relaxed.owl FYPO:0003531 biolink:NamedThing normal peroxisome size A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which peroxisome size is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003702 biolink:NamedThing normal microtubule cytoskeleton morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the microtubule cytoskeleton is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003750 biolink:NamedThing normal nuclear pore density A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a normal number of nuclear pore complexes. FYPO_relaxed.owl FYPO:0003751 biolink:NamedThing normal nuclear envelope morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the nuclear envelope is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003780 biolink:NamedThing normal nuclear envelope morphology during mitosis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the nuclear envelope is normal (i.e. indistinguishable from wild type) during mitosis. FYPO_relaxed.owl FYPO:0003781 biolink:NamedThing normal nuclear envelope morphology during mitotic interphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the nuclear envelope is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0003808 biolink:NamedThing normal mitochondrial motility A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the movement of mitochondria is normal (i.e. indistinguishable from wild type). Mitochondria normally form tips that grow and shrink stochastically. FYPO_relaxed.owl FYPO:0004015 biolink:NamedThing mitochondria present in normal numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a normal number of mitochondria. FYPO_relaxed.owl FYPO:0004247 biolink:NamedThing normal vacuolar morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the fungal-type vacuole is normal (i.e. indistinguishable from wild type).. FYPO_relaxed.owl FYPO:0004722 biolink:NamedThing normal nuclear microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the morphology of nuclear microtubules is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004739 biolink:NamedThing normal actin cytoskeleton during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, or morphology of the actin cytoskeleton is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004740 biolink:NamedThing normal actomyosin contractile ring A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the position, composition or morphology of the of the actomyosin contractile ring is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004824 biolink:NamedThing normal rDNA copy number A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is normal (within the range in wild type cells). FYPO_relaxed.owl FYPO:0005445 biolink:NamedThing normal telomere 3' overhang length during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the length of the single-stranded telomeric 3' overhang is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006213 biolink:NamedThing normal septum morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of the septum is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006235 biolink:NamedThing normal level of macromolecular complex A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount of any macromolecular complex present in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006324 biolink:NamedThing normal septin ring morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of the septin ring is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006513 biolink:NamedThing normal telomere morphology during vegetative growth A physical cellular phenotype in which the size, shape, or structure of the telomere is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0006791 biolink:NamedThing lipid droplets present in normal numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a normal number of lipid droplets. FYPO_relaxed.owl FYPO:0006981 biolink:NamedThing normal cell wall polysaccharide composition during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the levels and proportions of polysaccharides in the cell wall are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006982 biolink:NamedThing normal cell wall morphology during vegetative growth A physical cellular phenotype in which the size, shape, and structure of the cell wall are normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0007030 biolink:NamedThing normal cell wall monosaccharide composition during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the levels and proportions of monosaccharides in the cell wall are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007106 biolink:NamedThing normal mitotic spindle morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the mitotic spindle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007208 biolink:NamedThing normal microtubule bundle length during mitotic interphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which microtubule bundle length is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007412 biolink:NamedThing normal mitotic spindle orientation A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the orientation of the mitotic spindle is normal (i.e. indistinguishable from wild type, parallel with the long axis of the cell). FYPO_relaxed.owl FYPO:0007519 biolink:NamedThing normal DNA volume A cell phenotype observed in the vegetative growth phase of the life cycle in which DNA occupies a normal (i.e. indistinguishable from wild type) portion of the total nuclear volume. The nuclear volume itself is also normal. FYPO_relaxed.owl FYPO:0004944 biolink:NamedThing decreased mitochondrial membrane potential A physical cellular phenotype in which the mitochondrial membrane potential, i.e. the electric potential existing across the mitochondrial membrane, is smaller than normal. FYPO_relaxed.owl FYPO:0004957 biolink:NamedThing altered level of substance in mitochondrion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the mitochondrion differs from normal. FYPO_relaxed.owl FYPO:0005419 biolink:NamedThing abnormal mitochondrial crista morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the mitochondrial cristae is abnormal. FYPO_relaxed.owl FYPO:0007737 biolink:NamedThing increased mitochondrial membrane potential A physical cellular phenotype in which the mitochondrial membrane potential, i.e. the electric potential existing across the mitochondrial membrane, is greater than normal. FYPO_relaxed.owl FYPO:0000364 biolink:NamedThing abnormal plasma membrane morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the plasma membrane is abnormal. FYPO_relaxed.owl FYPO:0003136 biolink:NamedThing excess plasma membrane present A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more plasma membrane than normal. Excess plasma membrane may appear as bubble-like structures inside the cell, and may be concentrated in the mating projection during conjugation. FYPO_relaxed.owl FYPO:0005824 biolink:NamedThing increased plasma membrane permeability A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the permeability of the plasma membrane to one or more substances is greater than normal. FYPO_relaxed.owl FYPO:0006227 biolink:NamedThing abnormal plasma membrane potential A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the plasma membrane potential, i.e. the electric potential existing across the plasma membrane, is abnormal. FYPO_relaxed.owl FYPO:0000366 biolink:NamedThing decreased RNA localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA localization is decreased. FYPO_relaxed.owl FYPO:0000368 biolink:NamedThing abnormal vacuolar morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the fungal-type vacuole is abnormal. FYPO_relaxed.owl FYPO:0002257 biolink:NamedThing abnormal vacuolar morphology A physical cellular phenotype in which the size, shape, or structure of the fungal-type vacuole is abnormal. FYPO_relaxed.owl FYPO:0005178 biolink:NamedThing abnormal vacuolar morphology during nitrogen starvation A physical cellular phenotype in which the size, shape, or structure of the fungal-type vacuole is abnormal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0002038 biolink:NamedThing abnormal deadenylation-independent decapping of nuclear-transcribed mRNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which deadenylation-independent decapping of nuclear-transcribed mRNA is abnormal. This decapping process is cleavage of the 5'-cap of a nuclear-transcribed mRNA, independent of poly(A) tail shortening. All RNA decapping may be abnormal, or one or more specific RNA molecules may be selectively affected. FYPO_relaxed.owl FYPO:0003468 biolink:NamedThing normal RNA splicing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA splicing is normal (i.e. indistinguishable from wild type). All RNA splicing may be normal, or one splicing of or more specific RNA molecules may be specifically assayed. FYPO_relaxed.owl FYPO:0003916 biolink:NamedThing abnormal nonsense-mediated decay A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the degradation of messenger RNA (mRNA) molecules that contain nonsense mutations is abnormal. FYPO_relaxed.owl FYPO:0003947 biolink:NamedThing normal nonsense-mediated decay A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the degradation of messenger RNA (mRNA) molecules that contain nonsense mutations is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006808 biolink:NamedThing abnormal deadenylation-dependent decay A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the degradation of messenger RNA (mRNA) molecules via the deadenylation-dependent pathway, which includes poly(A) tail shortening, is abnormal. FYPO_relaxed.owl FYPO:0003551 biolink:NamedThing abnormal RNA catabolic process A cellular process phenotype in which an RNA catabolic process is abnormal. FYPO_relaxed.owl FYPO:0006250 biolink:NamedThing abnormal tRNA aminoacylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA aminoacylation, the formation of an ester bond between a tRNA molecule and an amino acid specified by the tRNA anticodon, is abnormal. All tRNAs aminoacylation may be abnormal, or the aminoacylation of one or more specific tRNAs may be affected. FYPO_relaxed.owl FYPO:0000372 biolink:NamedThing decreased RNA modification A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA modification is decreased. All RNA modification may be decreased, or one or more specific RNA modifications may be selectively affected. FYPO_relaxed.owl FYPO:0000373 biolink:NamedThing decreased rate of RNA modification A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of RNA modification is decreased. FYPO_relaxed.owl FYPO:0000374 biolink:NamedThing increased RNA modification A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of RNA modification is increased. All RNA modification may be increased, or one or more specific RNA modifications may be selectively affected. FYPO_relaxed.owl FYPO:0001172 biolink:NamedThing abnormal 7-methylguanosine cap hypermethylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to form a 2,2,7-trimethylguanosine cap structure is abnormal. FYPO_relaxed.owl FYPO:0001765 biolink:NamedThing abnormal tRNA modification A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA modification, the covalent alteration of one or more nucleotides within a tRNA molecule, is abnormal. FYPO_relaxed.owl FYPO:0005015 biolink:NamedThing abnormal rRNA modification A cellular process phenotype observed in the vegetative growth phase of the life cycle in which rRNA modification, the covalent alteration of one or more nucleotides within an rRNA molecule, is abnormal. FYPO_relaxed.owl FYPO:0008111 biolink:NamedThing abnormal snRNA modification A cellular process phenotype observed in the vegetative growth phase of the life cycle in which snRNA modification is abnormal. All snRNA modification may be abnormal, or one or more specific snRNA modifications may be selectively affected. FYPO_relaxed.owl FYPO:0006275 biolink:NamedThing increased pyknosis during stationary phase A cellular process phenotype in which pyknosis, the form of chromatin condensation typical of cell death by apoptosis, occurs at a greater frequency than normal when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0006276 biolink:NamedThing increased karyorrhexis during stationary phase A cellular process phenotype in which karyorrhexis, the nuclear fragmentation typical of cell death by apoptosis, occurs at a greater frequency than normal when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0000378 biolink:NamedThing normal apoptosis A cellular process phenotype in which apoptosis is normal (i.e. indistinguishable from wild type). Apoptosis is a form of cell death characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. FYPO_relaxed.owl FYPO:0000411 biolink:NamedThing normal mitotic cell cycle A cellular process phenotype in which mitotic cell cycle progression is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000426 biolink:NamedThing normal endocytosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000472 biolink:NamedThing normal mating type switching A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mating type switching is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000494 biolink:NamedThing normal mitochondrial genome maintenance A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial genome maintenance is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000535 biolink:NamedThing normal mitotic spindle pole body localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body localization is normal (i.e. indistinguishable from wild type). Spindle pole body localization is the process in which a whole spindle pole body is transported to, or maintained in, a specific location. FYPO_relaxed.owl FYPO:0000578 biolink:NamedThing normal gene silencing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gene silencing is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000596 biolink:NamedThing normal transposition A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transposition is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000601 biolink:NamedThing normal vacuolar transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuolar transport is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000673 biolink:NamedThing normal septum assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septum assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000740 biolink:NamedThing normal cellular pigment accumulation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular pigment accumulation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000856 biolink:NamedThing normal nucleosome positioning A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning is normal (i.e. indistinguishable from wild type). Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another. FYPO_relaxed.owl FYPO:0000897 biolink:NamedThing normal mitochondrial fission A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission, the division of a mitochondrion into two or more separate compartments, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000898 biolink:NamedThing normal mitochondrial fusion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fusion, the merging of two or more separate mitochondria into a single compartment, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000899 biolink:NamedThing normal microtubule cytoskeleton organization during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule cytoskeleton organization is normal (i.e. indistinguishable from wild type). Microtubule cytoskeleton organization is the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. FYPO_relaxed.owl FYPO:0001072 biolink:NamedThing normal myo-inositol import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which myo-inositol import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001169 biolink:NamedThing normal proton transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which proton (H+) transport is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001215 biolink:NamedThing normal protein complex assembly during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of a protein complex at the cellular level is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001293 biolink:NamedThing normal cell wall biogenesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell wall biogenesis is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001294 biolink:NamedThing normal actin cortical patch localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch localization is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001366 biolink:NamedThing normal actin cytoskeleton organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cytoskeleton organization is normal (i.e. indistinguishable from wild type). Actin cytoskeleton organization is the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. FYPO_relaxed.owl FYPO:0001596 biolink:NamedThing normal amino acid import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which amino acid import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001668 biolink:NamedThing normal protein processing during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein processing is normal (i.e. indistinguishable from wild type). Protein processing is any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. FYPO_relaxed.owl FYPO:0001760 biolink:NamedThing normal cell separation after cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cell separation after cytokinesis is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001805 biolink:NamedThing normal adenine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which adenine import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001806 biolink:NamedThing normal guanine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which guanine import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001845 biolink:NamedThing normal kinetochore organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which kinetochore organization is normal (i.e. indistinguishable from wild type). Kinetochore organization is the assembly, arrangement of constituent parts, or disassembly of kinetochores and their associated proteins. FYPO_relaxed.owl FYPO:0002085 biolink:NamedThing normal vegetative cell growth A cellular process phenotype in which the growth of a cell is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle. Cell growth is the process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. FYPO_relaxed.owl FYPO:0002335 biolink:NamedThing normal chromatin silencing A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is normal (i.e. indistinguishable from wild type). Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core). FYPO_relaxed.owl FYPO:0002350 biolink:NamedThing normal stress granule assembly during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002390 biolink:NamedThing normal mitotic sister chromatid cohesion A cellular process phenotype in which mitotic sister chromatid cohesion is normal (i.e. indistinguishable from wild type). Mitotic sister chromatid cohesion is the process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. FYPO_relaxed.owl FYPO:0002716 biolink:NamedThing normal vacuole fusion during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole fusion, the merging of two vacuole membranes to form a single vacuole, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002805 biolink:NamedThing normal sodium import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which sodium ion import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003082 biolink:NamedThing normal genetic imprinting at mating-type locus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which genetic imprinting at the mating-type locus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003193 biolink:NamedThing normal rate of microtubule depolymerization during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003225 biolink:NamedThing normal rate of microtubule polymerization during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of microtubule polymerization, i.e. the addition of tubulin dimers to a microtubule, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003294 biolink:NamedThing normal UDP-galactose transmembrane transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UDP-galactose transmembrane transport is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003353 biolink:NamedThing normal DNA double-strand break formation at mating-type locus A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which DNA double-strand break formation is normal (i.e. indistinguishable from wild type) during gene conversion at the mating-type locus. FYPO_relaxed.owl FYPO:0003594 biolink:NamedThing normal anaphase-promoting complex-dependent protein catabolic process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of ubiquitin-dependent protein degradation with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004004 biolink:NamedThing normal pre-replicative complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which pre-replicative complex assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004267 biolink:NamedThing normal septum disassembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum disassembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004504 biolink:NamedThing normal proteasome localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which proteasome localization is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005019 biolink:NamedThing normal duration of septum assembly A cell cycle phenotype observed in the vegetative growth phase of the life cycle in which the duration of septum assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005110 biolink:NamedThing normal sodium export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of sodium ions out of a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005160 biolink:NamedThing normal cell cycle progression following cellular response to hydroxyurea A cellular process phenotype in which cell cycle progression is normal (i.e. indistinguishable from wild type) after exposure to hydroxyurea. FYPO_relaxed.owl FYPO:0005166 biolink:NamedThing normal spatio-temporal regulation of replication fork localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the spatio-temporal pattern of localization of replication forks into nuclear foci is normal (i.e. indistinguishable from wild type). Normally, replication forks appear organized into foci outside the nucleolus in early S phase. As S phase progresses, the number of foci first increases, then decreases, and the remaining foci concentrate within the nucleolus or at the nucleolar periphery. The last replication foci remaining at the end of S phase are one or two large spots at the nucleolar border. FYPO_relaxed.owl FYPO:0005313 biolink:NamedThing normal maintenance of mitotic sister chromatid cohesion A cellular process phenotype in which maintenance of mitotic sister chromatid cohesion is normal (i.e. indistinguishable from wild type). Maintenance of mitotic sister chromatid cohesion is the process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the mitotic spindle, and congress to the metaphase plate. FYPO_relaxed.owl FYPO:0005465 biolink:NamedThing normal cell polarity A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment or maintenance of cell polarity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005493 biolink:NamedThing normal endosome to Golgi transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the transport of proteins or other substances from the endosome to the Golgi is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005720 biolink:NamedThing normal mitotic metaphase chromosome recapture A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromosome recapture is normal (i.e. indistinguishable from wild type) during metaphase of mitosis. Chromosome recapture is the reattachment of chromosomes which have become detached from the spindle. FYPO_relaxed.owl FYPO:0005787 biolink:NamedThing normal spatial extent of double-strand break processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break processing extends for a normal (i.e. indistinguishable from wild type) distance from the break site. Double-strand break processing is the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang. FYPO_relaxed.owl FYPO:0005804 biolink:NamedThing normal protein movement within plasma membrane during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of one or more proteins within the plasma membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005816 biolink:NamedThing normal microtubule-based movement A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule-based movement is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005945 biolink:NamedThing normal frequency of break-induced loss of heterozygosity A cell phenotype observed in the vegetative growth phase of the life cycle in which chromosomal truncation that would result in the loss of one of two different alleles of a gene occurs at a normal (i.e. indistinguishable from wild type) frequency. FYPO_relaxed.owl FYPO:0005975 biolink:NamedThing normal lithium export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which lithium ion export from the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005994 biolink:NamedThing normal mRNA deadenylation A metabolism phenotype observed in the vegetative growth phase of the life cycle in which shortening of the poly(A) tail of a nuclear-transcribed mRNA is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006256 biolink:NamedThing normal mitotic cohesin unloading A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin unloading is normal (i.e. indistinguishable from wild type). Cohesin unloading is the topological unlinking of a cohesin ring complex from chromatin, which negatively regulates sister chromatid cohesion. FYPO_relaxed.owl FYPO:0006319 biolink:NamedThing normal extent of DNA resection during replication fork processing A cell phenotype observed in the vegetative growth phase of the life cycle in which the extent of DNA resection upstream of a stalled replication fork is normal (i.e. indistinguishable from wild type). DNA resection is the 5'-to-3' degradation of one strand of DNA, leaving a stretch of single-stranded DNA. FYPO_relaxed.owl FYPO:0006320 biolink:NamedThing normal replication slippage during replication fork processing A cell phenotype observed in the vegetative growth phase of the life cycle in which the increase in small deletions or duplications ("replication slippage") that normally results from processing arrested replication forks is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006733 biolink:NamedThing normal CMG complex progression from replication origin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which movement of the CMG complex away from replication origins during DNA replication is normal. FYPO_relaxed.owl FYPO:0006811 biolink:NamedThing normal gross chromosomal rearrangement frequency A cell phenotype in which large chromosomal rearrangements occur at a normal (i.e. indistinguishable from wild type) frequency. Chromosomal rearrangements may include deletions, duplications, inversions, and translocations. FYPO_relaxed.owl FYPO:0006923 biolink:NamedThing normal DNA recombination frequency at mitotic DNA replication fork barriers A regulation phenotype in which the frequency of DNA recombination is normal (i.e. indistinguishable from wild type) at DNA replication fork barriers. FYPO_relaxed.owl FYPO:0006986 biolink:NamedThing normal spatial extent of heterochromatin assembly to boundary element IRL A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled up to, but not beyond, the IRL boundary element in the silent mating-type cassette, as in wild type. FYPO_relaxed.owl FYPO:0007007 biolink:NamedThing normal DNA recombination frequency downstream of mitotic DNA replication fork barriers A regulation phenotype in which the frequency of DNA recombination is normal (i.e. indistinguishable from wild type) downstream of DNA replication fork barriers. FYPO_relaxed.owl FYPO:0007055 biolink:NamedThing normal endosome organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endosome organization is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007066 biolink:NamedThing normal 90S preribosome assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of the 90S preribosome is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007169 biolink:NamedThing normal microtubule bundle formation during mitotic spindle assembly A cellular process phenotype in which microtubule bundle formation that takes place as part of mitotic spindle assembly, and which normally results in a parallel arrangement of microtubules, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007254 biolink:NamedThing normal replication fork processing A cell phenotype observed in the vegetative growth phase of the life cycle in which replication fork processing is normal (i.e. indistinguishable from wild type). Replication fork processing is process in which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired and replication is restarted. FYPO_relaxed.owl FYPO:0007378 biolink:NamedThing normal spindle pole body-led chromosome movement during mitotic interphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which rapid, back-and-forth movement of the mitotic spindle pole body (SPB), and associated chromosome movement, is normal (i.e. indistinguishable from wild type). SPB oscillation occurs during mitotic interphase (as well as prophase) and is restricted to a small space. FYPO_relaxed.owl FYPO:0007671 biolink:NamedThing normal transcription scaling A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the coordination of transcription rates to scale linearly with cell size is normal (i.e. indistinguishable from wild type). Transcriptional scaling maintains biomolecule concentrations as cells grow and divide. Total RNA or a specific RNA may be measured. FYPO_relaxed.owl FYPO:0007676 biolink:NamedThing normal intracellular sterol transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the directed movement of sterols within cells is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007689 biolink:NamedThing normal cell growth polarization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cells can grow in a normally (i.e. as in wild type) polarized manner as in the presence of a polarity landmark. The landmark itself may be in a normal or abnormal location. FYPO_relaxed.owl FYPO:0007740 biolink:NamedThing normal nucleolar ring assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleolar ring assembly is normal (i.e. indistinguishable from wild type). Nucleolar rings are structures located at the nucleolar periphery where several nuclear factors are reversibly aggregated and sequestered during acute heat stress. FYPO_relaxed.owl FYPO:0007827 biolink:NamedThing normal actomyosin contractile ring organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin contractile ring organization is normal (i.e. indistinguishable from wild type). The process results in the assembly, arrangement of constituent parts, or disassembly of the actomyosin contractile ring. FYPO_relaxed.owl FYPO:0007940 biolink:NamedThing normal chromatin organization A cellular process phenotype in which any process of chromatin organization is normal (i.e. indistinguishable from wild type). Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. FYPO_relaxed.owl FYPO:0008138 biolink:NamedThing normal nucleocytoplasmic transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleocytoplasmic tranport is normal (i.e. indistinguishable from wild type). Nucleocytoplasmic transportport is the directed movement of any substance into or out of the nucleus; import or export of all substances or a specific substance may be affected. FYPO_relaxed.owl FYPO:0000381 biolink:NamedThing decreased macroautophagy A cellular process phenotype in which the occurrence of macroautophagy is decreased. FYPO_relaxed.owl FYPO:0000382 biolink:NamedThing decreased rate of macroautophagy A cellular process phenotype in which the rate, or speed, of macroautophagy is decreased. FYPO_relaxed.owl FYPO:0000383 biolink:NamedThing delayed onset of macroautophagy A cellular process phenotype in which macroautophagy begins later than normal. FYPO_relaxed.owl FYPO:0000384 biolink:NamedThing increased macroautophagy A cellular process phenotype in which the occurrence of macroautophagy is increased. FYPO_relaxed.owl FYPO:0004670 biolink:NamedThing abnormal macroautophagy during nitrogen starvation A cellular process phenotype in which macroautophagy is abnormal when the cell is subject to nitrogen starvation. Macroautophagy is the major pathway by which cells digest parts of their own cytoplasm. FYPO_relaxed.owl FYPO:0008085 biolink:NamedThing abnormal nucleophagy A cellular process phenotype in which autophagic degradation of the nucleus is abolished. FYPO_relaxed.owl FYPO:0000385 biolink:NamedThing normal macroautophagy A cellular process phenotype in which macroautophagy is normal (i.e. indistinguishable from wild type). Macroautophagy is the major pathway by which cells digest parts of their own cytoplasm. FYPO_relaxed.owl FYPO:0002496 biolink:NamedThing normal metabolic process A cellular process phenotype in which a cellular metabolic process is normal (i.e. indistinguishable from wild type). A metabolic process is any set of chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. FYPO_relaxed.owl FYPO:0000488 biolink:NamedThing normal meiotic recombination A cellular process phenotype in which reciprocal meiotic recombination is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000529 biolink:NamedThing normal peroxisome degradation A cellular process phenotype in which peroxisome degradation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004849 biolink:NamedThing normal protein metabolic process A cellular process phenotype in which a protein metabolic process is normal (i.e. indistinguishable from wild type). A protein metabolic process is a series of chemical reactions and pathways involving a specific protein. FYPO_relaxed.owl FYPO:0004850 biolink:NamedThing normal RNA metabolic process A cellular process phenotype in which a protein metabolic process is normal (i.e. indistinguishable from wild type). An RNA metabolic process is a series of chemical reactions and pathways involving any type of RNA. FYPO_relaxed.owl FYPO:0005136 biolink:NamedThing normal meiotic DNA double-strand break formation A cellular process phenotype in which generation of double-strand breaks at defined hotspots throughout the genome during meiosis I is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005138 biolink:NamedThing normal meiotic recombination double-strand break repair A cellular process phenotype in which the repair of double-strand breaks formed as part of meiotic recombination is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000387 biolink:NamedThing decreased biofilm formation A cellular process phenotype in which the occurrence of biofilm formation is decreased. FYPO_relaxed.owl FYPO:0000388 biolink:NamedThing increased biofilm formation A cellular process phenotype in which the occurrence of biofilm formation is increased. FYPO_relaxed.owl FYPO:0000389 biolink:NamedThing cell cycle arrest at mitotic START A cellular process phenotype in which traversing the start control point of the mitotic cell cycle is arrested. FYPO_relaxed.owl FYPO:0000444 biolink:NamedThing abnormal mitotic cell cycle arrest with replicated DNA A cellular process phenotype in which progression through the mitotic cell cycle is arrested when cells have replicated genomic DNA, under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0000839 biolink:NamedThing inviable elongated mononucleate aseptate cell A cell phenotype in which a cell contains one nucleus, has no septum, is elongated, and is inviable. Progression through the mitotic cell cycle is arrested in all inviable elongated mononucleate aseptate cells. FYPO_relaxed.owl FYPO:0001028 biolink:NamedThing abnormal cell cycle arrest in mitotic interphase A cellular process phenotype in which progression through the mitotic cell cycle is arrested in any part of interphase, under conditions where arrest is not a normal occurrence. FYPO_relaxed.owl FYPO:0001430 biolink:NamedThing abnormal mitotic cell cycle arrest with unreplicated DNA A cellular process phenotype in which progression through the mitotic cell cycle is arrested before cells have replicated genomic DNA, under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0002888 biolink:NamedThing mitotic cell cycle arrest before cell separation A cellular process phenotype in which the mitotic cell cycle is arrested after the septum has formed, but before cells have separated, under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0003738 biolink:NamedThing abnormal mitotic cell cycle arrest with condensed chromosomes A cellular process phenotype in which progression through the mitotic cell cycle is arrested when cells have condensed chromosomes, but show no other signs of having entered mitosis or M phase, under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0003759 biolink:NamedThing inviable after spore germination, single or double cell division, arrest with single nucleus A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and all cells produced arrest the cell cycle with a single nucleus and then die. FYPO_relaxed.owl FYPO:0005335 biolink:NamedThing abnormal cell cycle arrest at mitotic G2/M phase transition during glucose starvation A cellular process phenotype in which progression through mitotic cell cycle arrest at the mitotic G2/M phase transition occurs abnormally when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0000837 biolink:NamedThing cell cycle arrest in mitotic interphase A cellular process phenotype in which progression through the mitotic cell cycle is arrested in any part of interphase. Includes normal and abnormal occurrences of arrest. FYPO_relaxed.owl FYPO:0000445 biolink:NamedThing cell cycle arrest in mitotic G1 phase A cellular process phenotype in which progression through the mitotic cell cycle is arrested in G1 phase. FYPO_relaxed.owl FYPO:0000446 biolink:NamedThing cell cycle arrest at mitotic G2/M phase transition A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition. FYPO_relaxed.owl FYPO:0000391 biolink:NamedThing normal passage through START of mitotic cell cycle A cellular process phenotype in which traversing the start control point of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001927 biolink:NamedThing normal cell cycle regulation during cellular response to ionizing radiation A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ionizing radiation is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to ionizing radiation. FYPO_relaxed.owl FYPO:0001929 biolink:NamedThing normal cell cycle regulation during cellular response to hydroxyurea A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to hydroxyurea is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to hydroxyurea. FYPO_relaxed.owl FYPO:0002996 biolink:NamedThing normal negative regulation of DNA replication during cellular response to hydrogen peroxide A regulation phenotype in which regulation of DNA replication during the mitotic cell cycle is normal (i.e. indistinguishable from wild type) during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0004014 biolink:NamedThing normal mitotic cell cycle regulation during cellular response to UV A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ultraviolet light (UV) is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to UV. FYPO_relaxed.owl FYPO:0005054 biolink:NamedThing normal cell cycle regulation during cellular response to latrunculin A A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to latrunculin A is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to latrunculin A. FYPO_relaxed.owl FYPO:0005107 biolink:NamedThing normal regulation of mitotic DNA replication initiation A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of mitotic DNA replication initiation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005207 biolink:NamedThing normal mitotic cell cycle regulation upon nitrogen source shift A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle is normal (i.e. indistinguishable from wild type) when cells are shifted from one nitrogen source to another. Normally, cell division is delayed upon shifting from a poor to a rich nitrogen source, and accelerated upon shifting from a rich to a poor nitrogen source. FYPO_relaxed.owl FYPO:0005373 biolink:NamedThing normal mitotic cell cycle regulation during cellular response to methyl methanesulfonate A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to methyl methanesulfonate (MMS) is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to MMS. FYPO_relaxed.owl FYPO:0005728 biolink:NamedThing normal deactivation of mitotic spindle assembly checkpoint A cell cycle checkpoint phenotype in which deactivation of the mitotic spindle assembly checkpoint is normal (i.e. indistinguishable from wild type. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. FYPO_relaxed.owl FYPO:0006578 biolink:NamedThing normal mitotic G2 DNA damage checkpoint A cell cycle checkpoint phenotype in which the mitotic G2 DNA damage checkpoint is normal (i.e. indistinguishable from wild type). The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage. FYPO_relaxed.owl FYPO:0006720 biolink:NamedThing normal cell cycle regulation during cellular response to osmotic stress A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to osmotic stress is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to osmotic stress. FYPO_relaxed.owl FYPO:0006865 biolink:NamedThing normal mitotic DNA damage checkpoint during cellular response to streptonigrin A cell cycle checkpoint phenotype in which any mitotic DNA damage checkpoint is normal (i.e. indistinguishable from wild type) when the cell is exposed to streptonigrin. A DNA damage checkpoint normally regulates progression through the cell cycle in response to DNA damage. FYPO_relaxed.owl FYPO:0008218 biolink:NamedThing abnormal mitotic S/G2 phase transition A cellular process phenotype in which a cell does not execute a mitotic S/G2 cell cycle phase transition normally. FYPO_relaxed.owl FYPO:0000400 biolink:NamedThing abnormal cell cycle arrest at mitotic G2/M phase transition A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the G2/M transition, under conditions where arrest is not a normal occurrence. FYPO_relaxed.owl FYPO:0000611 biolink:NamedThing abnormal cell cycle arrest in mitotic S phase A cellular process phenotype in which progression through the mitotic cell cycle is abnormally arrested in S phase. FYPO_relaxed.owl FYPO:0003449 biolink:NamedThing abnormal cell cycle arrest at mitotic G1/S phase transition A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G1/S phase transition, under conditions where arrest is not a normal occurrence. FYPO_relaxed.owl FYPO:0005097 biolink:NamedThing abnormal cell cycle arrest in mitotic G1 phase A cellular process phenotype in which progression through the mitotic cell cycle is abnormally arrested during G1 phase. Arrest may either occur under conditions where arrest is not a normal occurrence, or may progress differently from normal under conditions where arrest normally does take place. FYPO_relaxed.owl FYPO:0000405 biolink:NamedThing normal mitotic G2/M phase transition A cellular process phenotype in which the G2/M transition of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002741 biolink:NamedThing normal mitotic cell cycle process A cellular process phenotype in which a cell executes a mitotic cell cycle process normally (i.e. indistinguishably from wild type). A mitotic cell cycle process is any of the processes that form part of the mitotic cell cycle, and thereby ensures successive accurate and complete genome replication and chromosome segregation. FYPO_relaxed.owl FYPO:0001007 biolink:NamedThing normal mitosis A cellular process phenotype in which mitosis is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001367 biolink:NamedThing normal cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytokinesis is normal (i.e. indistinguishable from wild type). Cytokinesis is part of the cell cycle and results in the division of the cytoplasm of a cell and its separation into two daughter cells. FYPO_relaxed.owl FYPO:0001513 biolink:NamedThing normal mitotic sister chromatid segregation A cellular process phenotype in which mitotic sister chromatid segregation is normal (i.e. indistinguishable from wild type). Mitotic sister chromatid segregation is the entire process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. FYPO_relaxed.owl FYPO:0001703 biolink:NamedThing normal mitotic cell cycle checkpoint A cell cycle phenotype in which a specific mitotic cell cycle checkpoint is normal (i.e. indistinguishable from wild type). A cell cycle checkpoint controls cell cycle progression by monitoring the timing and integrity of specific cell cycle events. FYPO_relaxed.owl FYPO:0001761 biolink:NamedThing normal mitotic G1/S phase transition A cellular process phenotype in which the G1/S transition of the mitotic cell cycle is normal. FYPO_relaxed.owl FYPO:0002559 biolink:NamedThing normal protein localization to actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003876 biolink:NamedThing normal cytokinesis checkpoint A cell cycle checkpoint phenotype in which the cytokinesis after mitosis checkpoint of a mitotic cell cycle is normal (i.e. indistinguishable from wild type). The cytokinesis after mitosis checkpoint normally delays the G2/M transition of a mitotic cell cycle if cytokinesis was not completed correctly in the previous cell cycle. FYPO_relaxed.owl FYPO:0004097 biolink:NamedThing normal actomyosin contractile ring contraction A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction is normal (i.e. indistinguishable from wild type). Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts. FYPO_relaxed.owl FYPO:0004301 biolink:NamedThing normal mitotic sister chromatid separation A cellular process phenotype in which mitotic sister chromatid separation is normal (i.e. indistinguishable from wild type). Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis. FYPO_relaxed.owl FYPO:0004367 biolink:NamedThing normal mitotic spindle assembly A cellular process phenotype in which assembly of the mitotic spindle is normal (i.e. indistinguishable from wild type). Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle. FYPO_relaxed.owl FYPO:0004396 biolink:NamedThing normal mitotic spindle elongation A spindle phenotype in which mitotic spindle elongation, i.e. the process of lengthening the distance between poles of the mitotic spindle, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004429 biolink:NamedThing normal rate of mitotic spindle elongation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004629 biolink:NamedThing normal mitotic DNA replication A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic DNA replication is normal. FYPO_relaxed.owl FYPO:0005312 biolink:NamedThing normal establishment of mitotic sister chromatid cohesion A cellular process phenotype in which establishment of mitotic sister chromatid cohesion is normal (i.e. indistinguishable from wild type). Establishment of mitotic sister chromatid cohesion is the process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005380 biolink:NamedThing normal mitotic spindle pole body duplication A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle pole body duplication is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006050 biolink:NamedThing normal rate of mitotic sister chromatid separation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic sister chromatid separation is normal (i.e. indistinguishable from wild type). Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis. FYPO_relaxed.owl FYPO:0006482 biolink:NamedThing normal mitotic cohesin ssDNA (lagging strand) loading A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin ssDNA (lagging strand) loading is normal (i.e. indistinguishable from wild type) during the mitotic cell cycle. Cohesin ssDNA (lagging strand) loading is the topological linking of a cohesin ring complex to single-stranded DNA, i.e. the lagging strand, in chromatin. FYPO_relaxed.owl FYPO:0006833 biolink:NamedThing normal onset of primary cell septum biogenesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum biogenesis begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events. FYPO_relaxed.owl FYPO:0006917 biolink:NamedThing normal onset of mitotic metaphase/anaphase transition A cellular process phenotype in which the metaphase/anaphase transition of mitosis begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events. FYPO_relaxed.owl FYPO:0006916 biolink:NamedThing normal cell cycle phase transition A cellular process phenotype in which a cell executes a cell cycle phase transition normally (i.e. indistinguishably from wild type). FYPO_relaxed.owl FYPO:0005637 biolink:NamedThing normal onset of metaphase/anaphase transition of meiosis I A cellular process phenotype in which the metaphase/anaphase transition of the first meiotic nuclear division begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events. FYPO_relaxed.owl FYPO:0004040 biolink:NamedThing mitotic cell cycle arrest phenotype A cell cycle phenotype that affects or involves the normal or abnormal occurrence of mitotic cell cycle arrest. In mitotic cell cycle arrest, progression through the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, or M). FYPO_relaxed.owl FYPO:0000408 biolink:NamedThing increased duration of cell cycle phase A cellular process phenotype in which the duration of one or more cell cycle phases is longer than normal. FYPO_relaxed.owl FYPO:0000410 biolink:NamedThing decreased duration of cell cycle phase A cellular process phenotype in which the duration of one or more cell cycle phases is shorter than normal. FYPO_relaxed.owl FYPO:0002738 biolink:NamedThing abnormal meiotic cell cycle phase A cellular process phenotype in which a cell does not proceed normally through a specific meiotic cell cycle phase. A meiotic cell cycle phase is any of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. FYPO_relaxed.owl FYPO:0003832 biolink:NamedThing normal cell cycle A cellular process phenotype in which cell cycle progression is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001025 biolink:NamedThing normally arrested mitotic cell cycle progression A cellular process phenotype in which mitotic cell cycle progression is arrested under conditions where arrest normally occurs. FYPO_relaxed.owl FYPO:0003833 biolink:NamedThing normal cell cycle phase A cellular process phenotype in which a cell proceeds normally through a specific cell cycle phase. A cell cycle phase is any of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. FYPO_relaxed.owl FYPO:0006915 biolink:NamedThing normal cell cycle process A cellular process phenotype in which a cell executes a cell cycle process normally (i.e. indistinguishably from wild type). A cell cycle process is any of the processes that form part of the cell cycle, and thereby ensures successive accurate and complete genome replication and chromosome segregation. FYPO_relaxed.owl FYPO:0001014 biolink:NamedThing abnormal membrane organization during nitrogen starvation A cellular process phenotype in which cellular membrane organization is abnormal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0001914 biolink:NamedThing abnormal prospore membrane formation A cellular process phenotype in which prospore membrane formation is abnormal. In prospore membrane formation, the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed. FYPO_relaxed.owl FYPO:0004525 biolink:NamedThing abnormal membrane organization during mating A cellular process phenotype in which cellular membrane organization is abnormal during mating. FYPO_relaxed.owl FYPO:0006671 biolink:NamedThing transient cell fusion during mating A cellular process phenotype in which cells fuse for a much shorter time than normal during mating, separate with incomplete exchange of cytosol contents, and the conjugation pore then reseals. FYPO_relaxed.owl FYPO:0007094 biolink:NamedThing increased duration of cell fusion during mating A cellular process phenotype in which cells fuse for a longer time than normal during mating. FYPO_relaxed.owl FYPO:0000416 biolink:NamedThing premature mitotic sister chromatid separation A cellular process phenotype in which mitotic sister chromatid separation begins before anaphase. FYPO_relaxed.owl FYPO:0000671 biolink:NamedThing abnormal rDNA separation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation at the rDNA repeat regions is abnormal. FYPO_relaxed.owl FYPO:0004507 biolink:NamedThing abolished centromeric DNA separation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation does not occur at the centromeric regions. The remainder of the sister chromatids may or may not separate. FYPO_relaxed.owl FYPO:0004705 biolink:NamedThing delayed onset of mitotic sister chromatid separation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation begins later than normal. FYPO_relaxed.owl FYPO:0005024 biolink:NamedThing abnormal mitotic sister chromatid arm separation A cellular process phenotype in which mitotic sister chromatid separation is abnormal along the chromosome arms. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis. FYPO_relaxed.owl FYPO:0005442 biolink:NamedThing abnormal telomeric DNA separation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation is abnormal at the telomeric regions. The remainder of the sister chromatids may or may not separate normally. FYPO_relaxed.owl FYPO:0007125 biolink:NamedThing mitotic sister chromatid separation in absence of mitotic spindle A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation begins when the mitotic spindle is not present. FYPO_relaxed.owl FYPO:0000422 biolink:NamedThing decreased endocytosis during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of endocytosis is decreased. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0000423 biolink:NamedThing decreased rate of endocytosis during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of endocytosis is decreased. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0000424 biolink:NamedThing delayed onset of endocytosis during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis begins later than normal. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0000425 biolink:NamedThing increased endocytosis during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of endocytosis is increased. A phenotype may affect endocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0006340 biolink:NamedThing endocytosis restricted to old cell end A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis occurs only at the old end of the cell during interphase of the mitotic cell cycle. Normally, endocytosis takes place at the old cell end throughout interphase, and also at the new end after NETO. FYPO_relaxed.owl FYPO:0006341 biolink:NamedThing abolished equatorial endocytosis during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endocytosis does not occur in the equatorial region of the cell during mitosis as in wild-type cells. FYPO_relaxed.owl FYPO:0006432 biolink:NamedThing normal vesicle-mediated transport during vegetative growth A transport phenotype observed in the vegetative growth phase of the life cycle in which vesicle-mediated transport is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001002 biolink:NamedThing abolished cell division prior to G0 entry A cellular process phenotype in which a cell does not undergo the normal two rounds of cell division prior to entering quiescence (G0). FYPO_relaxed.owl FYPO:0003877 biolink:NamedThing single cell division prior to G0 entry A cellular process phenotype in which a cell undergoes one round of cell division, instead of the normal two rounds, prior to entering quiescence (G0). FYPO_relaxed.owl FYPO:0000429 biolink:NamedThing delayed G0 to G1 transition A cellular process phenotype in which the G0 to G1 transition begins later than normal. FYPO_relaxed.owl FYPO:0000432 biolink:NamedThing decreased fermentation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of fermentation is decreased. FYPO_relaxed.owl FYPO:0000433 biolink:NamedThing increased fermentation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of fermentation is increased. FYPO_relaxed.owl FYPO:0000434 biolink:NamedThing normal fermentation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which fermentation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000503 biolink:NamedThing normal mitotic recombination A cellular process phenotype in which mitotic recombination is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000549 biolink:NamedThing normal protein modification during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein modification is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000566 biolink:NamedThing normal cellular respiration A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular respiration is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001133 biolink:NamedThing normal DNA replication A cellular process phenotype in which DNA replication is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001855 biolink:NamedThing normal transcription during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0002939 biolink:NamedThing normal nuclear mRNA catabolic process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an RNA catabolic process that degrades mRNA encoded in the nucleus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003653 biolink:NamedThing normal transcription elongation from RNA polymerase III promoter during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription elongation from an RNA polymerase III promoter occurs to a normal (i.e. indistinguishable from wild type) extent. FYPO_relaxed.owl FYPO:0004271 biolink:NamedThing normal cell septum edging catabolic process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dissolution of the cell septum edging material is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004529 biolink:NamedThing normal mitochondrial translation A metabolism phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial translation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005108 biolink:NamedThing normal rate of mitotic DNA replication elongation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA strand elongation involved in mitotic nuclear DNA replication is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005354 biolink:NamedThing normal site-specific DNA replication termination at RTS1 barrier A cellular process phenotype observed in the vegetative growth phase of the life cycle in which site-specific DNA replication termination at the RTS1 barrier in the mating type region is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005392 biolink:NamedThing normal DNA recombination frequency during cellular response to ionizing radiation A regulation phenotype in which the frequency of DNA recombination is normal (i.e. indistinguishable from wild type) during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0005541 biolink:NamedThing normal DNA recombination frequency at subtelomeric heterochromatin A regulation phenotype in which the frequency of DNA recombination is normal (i.e. indistinguishable from wild type) in subtelomeric regions. FYPO_relaxed.owl FYPO:0005993 biolink:NamedThing normal cytoplasmic translation A metabolism phenotype observed in the vegetative growth phase of the life cycle in which translation in the cytoplasm is normal (i.e. indistinguishable from wild type). Translation is the synthesis of a protein using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. FYPO_relaxed.owl FYPO:0006038 biolink:NamedThing normal cytoplasmic translational initiation A metabolism phenotype observed in the vegetative growth phase of the life cycle in which the initiation of translation in the cytoplasm is normal (i.e. indistinguishable from wild type). Translational initiation is he process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. FYPO_relaxed.owl FYPO:0006085 biolink:NamedThing normal snRNA pseudouridylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which intramolecular conversion of uridine to pseudouridine in an snRNA molecule is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006249 biolink:NamedThing normal tRNA aminoacylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA aminoacylation, the formation of an ester bond between a tRNA molecule and an amino acid specified by the tRNA anticodon, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006569 biolink:NamedThing normal DNA repair A cellular process phenotype observed in the vegetative growth phase of the life cycle in which DNA repair is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007153 biolink:NamedThing normal polyphosphate catabolism during cellular response to phosphate starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the breakdown of polyphosphate is normal (i.e. indistinguishable from wild type) during a cellular response to phosphate starvation. FYPO_relaxed.owl FYPO:0007154 biolink:NamedThing normal polyphosphate biosynthesis during cellular response to replete phosphate A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the biosynthesis of polyphosphate is normal (i.e. indistinguishable from wild type) during a cellular response to replete phosphate. FYPO_relaxed.owl FYPO:0007425 biolink:NamedThing normal gene conversion A DNA recombination phenotype observed in the vegetative growth phase of the life cycle in which gene conversion is normal (i.e. indistinguishably from wild type). FYPO_relaxed.owl FYPO:0007463 biolink:NamedThing normal transcription termination A cell phenotype observed in the vegetative growth phase of the life cycle in which the termination of RNA transcription from a DNA template is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008191 biolink:NamedThing normal replication fork arrest A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at a natural replication barrier is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000677 biolink:NamedThing abnormal protein localization to prospore membrane A transport phenotype in which protein localization to the prospore membrane is abnormal. FYPO_relaxed.owl FYPO:0001375 biolink:NamedThing abolished protein localization A cell phenotype in which a protein does not localize to, and is therefore absent from, a place where it is normally found. FYPO_relaxed.owl FYPO:0001440 biolink:NamedThing abnormal protein complex localization A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein complex is abnormal. FYPO_relaxed.owl FYPO:0002956 biolink:NamedThing abnormal protein localization to nucleus A cell phenotype in which the localization of a protein to the nucleus is abnormal. FYPO_relaxed.owl FYPO:0004090 biolink:NamedThing abnormal protein localization to microtubule cytoskeleton A cell phenotype in which the localization of a protein to the microtubule cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0004094 biolink:NamedThing abnormal protein localization during meiotic cell cycle A cell phenotype that affects the localization of a protein in a cell during the meiotic cell cycle. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. FYPO_relaxed.owl FYPO:0004996 biolink:NamedThing abnormal protein localization to chromosome A cell phenotype in which the localization of a protein to a specific location on a chromosome is abnormal. FYPO_relaxed.owl FYPO:0005987 biolink:NamedThing abnormal protein localization to cell tip A cell phenotype in which the localization of a protein to the cell tip is abnormal. FYPO_relaxed.owl FYPO:0005989 biolink:NamedThing abnormal protein localization during mating A cell phenotype that affects the localization of a protein in a cell during conjugation with cellular fusion. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. FYPO_relaxed.owl FYPO:0006377 biolink:NamedThing abnormal protein localization to endoplasmic reticulum A cell phenotype in which the localization of a protein to the endoplasmic reticulum is abnormal. FYPO_relaxed.owl FYPO:0006533 biolink:NamedThing abnormal protein localization to cell periphery A cell phenotype in which the localization of a protein to the cell periphery is abnormal. FYPO_relaxed.owl FYPO:0006606 biolink:NamedThing abnormal dynamic protein localization pattern A cell phenotype in which a protein that is normally dynamically localized to a specific place in the cell shows an abnormal temporal pattern of localization. For example, a protein may move to or from the location more or less frequently than normal. FYPO_relaxed.owl FYPO:0007577 biolink:NamedThing abnormal protein localization to actin cytoskeleton A cell phenotype in which the localization of a protein to the actin cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0007863 biolink:NamedThing abnormal protein localization to spindle A cell phenotype in which the localization of a protein to the mitotic or meiotic spindle is abnormal. FYPO_relaxed.owl FYPO:0007869 biolink:NamedThing abnormal protein localization to lateral cell cortex A cell phenotype in which the localization of a protein to the lateral cell cortex is abnormal. FYPO_relaxed.owl FYPO:0000902 biolink:NamedThing abnormal microtubule depolymerization during vegetative growth A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, is abnormal. FYPO_relaxed.owl FYPO:0001352 biolink:NamedThing abnormal chromatin organization during vegetative growth A cellular process phenotype in which any process of chromatin organization is abnormal in the vegetative growth phase of the life cycle. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. FYPO_relaxed.owl FYPO:0007403 biolink:NamedThing increased duration of anaphase-promoting complex presence A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the anaphase-promoting complex (APC) is present for longer than normal. The APC normally forms in prometaphase and disassembles before anaphase; in mutants it may remain present during anaphase. FYPO_relaxed.owl FYPO:0000449 biolink:NamedThing abnormal protein localization to centromere during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is abnormal. FYPO_relaxed.owl FYPO:0000452 biolink:NamedThing abnormal protein localization to chromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is abnormal. FYPO_relaxed.owl FYPO:0002839 biolink:NamedThing decreased protein localization to chromosome during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a specific location on a chromosome is decreased. FYPO_relaxed.owl FYPO:0002840 biolink:NamedThing increased protein localization to chromosome during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a specific location on a chromosome is increased. FYPO_relaxed.owl FYPO:0003108 biolink:NamedThing abnormal protein localization to telomere during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the telomere of a chromosome is abnormal. FYPO_relaxed.owl FYPO:0005597 biolink:NamedThing abnormal protein localization to centromere A cell phenotype in which the localization of a protein to the centromere of a chromosome is abnormal. FYPO_relaxed.owl FYPO:0005209 biolink:NamedThing abnormal protein localization to kinetochore A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is abnormal. FYPO_relaxed.owl FYPO:0006238 biolink:NamedThing decreased protein localization to centromere A cell phenotype in which the localization of a protein to the centromere of a chromosome is decreased. FYPO_relaxed.owl FYPO:0006239 biolink:NamedThing increased protein localization to centromere A cell phenotype in which the localization of a protein to the centromere of a chromosome is increased. FYPO_relaxed.owl FYPO:0006529 biolink:NamedThing abnormal protein localization to centromere during meiotic cell cycle A cell phenotype in which the localization of a protein to the centromere of a chromosome is abnormal during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0007648 biolink:NamedThing abnormal protein localization to pericentric heterochromatin A cell phenotype in which the localization of a protein to pericentric heterochromatin is abnormal. FYPO_relaxed.owl FYPO:0000450 biolink:NamedThing decreased protein localization to centromere during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is decreased. FYPO_relaxed.owl FYPO:0000451 biolink:NamedThing increased protein localization to centromere during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is increased. FYPO_relaxed.owl FYPO:0000634 biolink:NamedThing abolished protein localization to centromere during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome does not occur. FYPO_relaxed.owl FYPO:0001268 biolink:NamedThing abnormal protein localization to kinetochore during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is abnormal. FYPO_relaxed.owl FYPO:0002842 biolink:NamedThing decreased protein localization to centromere outer repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere outer repeat regions of a chromosome is decreased. FYPO_relaxed.owl FYPO:0003009 biolink:NamedThing increased protein localization to centromere outer repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere outer repeat regions of a chromosome is increased. FYPO_relaxed.owl FYPO:0004904 biolink:NamedThing decreased protein localization to centromere central core during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the central core of the centromeric regions is decreased. FYPO_relaxed.owl FYPO:0005306 biolink:NamedThing abnormal protein localization to centromeric chromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is abnormal. FYPO_relaxed.owl FYPO:0006175 biolink:NamedThing abnormal protein localization to centromere during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is abnormal during metaphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0002474 biolink:NamedThing decreased protein localization to double-strand break site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the region of a chromosome at which a DNA double-strand break has occurred is decreased. FYPO_relaxed.owl FYPO:0002909 biolink:NamedThing decreased protein localization to chromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is decreased. FYPO_relaxed.owl FYPO:0002925 biolink:NamedThing decreased protein localization to chromosome at CRE promoter A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to CRE promoter in a chromosome is decreased. FYPO_relaxed.owl FYPO:0003803 biolink:NamedThing decreased protein localization to telomere A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the telomere of a chromosome is decreased. FYPO_relaxed.owl FYPO:0003002 biolink:NamedThing decreased protein localization to centromere during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is decreased during metaphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004212 biolink:NamedThing decreased protein localization to kinetochore during meiosis I A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is decreased during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007760 biolink:NamedThing decreased protein localization to kinetochore during meiotic prophase II A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is decreased during prophase of the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0002475 biolink:NamedThing increased protein localization to double-strand break site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the region of a chromosome at which a DNA double-strand break has occurred is increased. FYPO_relaxed.owl FYPO:0003011 biolink:NamedThing increased protein localization to chromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased. FYPO_relaxed.owl FYPO:0003003 biolink:NamedThing increased protein localization to kinetochore during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is increased. FYPO_relaxed.owl FYPO:0005513 biolink:NamedThing increased protein localization to kinetochore during meiosis A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is increased during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0005598 biolink:NamedThing increased protein localization to centromere during meiotic cell cycle A cell phenotype in which the localization of a protein to the centromere of a chromosome is increased during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0005735 biolink:NamedThing increased protein localization to kinetochore during mitotic M phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is increased during mitotic M-phase. FYPO_relaxed.owl FYPO:0001679 biolink:NamedThing abnormal protein localization to chromatin A cell phenotype in which the localization of a protein to chromatin is abnormal. FYPO_relaxed.owl FYPO:0004718 biolink:NamedThing abnormal protein localization to heterochromatin A cell phenotype in which the localization of a protein to heterochromatin is abnormal. FYPO_relaxed.owl FYPO:0005051 biolink:NamedThing decreased protein localization to chromatin at RNA polymerase II-regulated genes during nitrogen starvation A cell phenotype in which the localization of a protein to regions of chromatin containing genes that can be transcribed by RNA polymerase II is decreased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006631 biolink:NamedThing decreased protein localization to chromatin A cell phenotype in which the localization of a protein to chromatin is decreased. FYPO_relaxed.owl FYPO:0001329 biolink:NamedThing decreased level of substance in cell during vegetative growth A cell phenotype in which the amount of a specific substance measured in a cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001080 biolink:NamedThing decreased polysaccharide level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001117 biolink:NamedThing decreased RNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0001197 biolink:NamedThing decreased cellular calcium level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001208 biolink:NamedThing substance absent from cell during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0001289 biolink:NamedThing decreased phospholipid level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phospholipid measured in a cell is lower than normal. A phospholipid is any lipid containing phosphoric acid as a mono- or di-ester. FYPO_relaxed.owl FYPO:0001324 biolink:NamedThing decreased protein level during vegetative growth A cell phenotype in which the amount of protein measured in a cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001412 biolink:NamedThing decreased cellular sulfide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-, also called acid labile sulfide) measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001534 biolink:NamedThing decreased cellular zinc level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001563 biolink:NamedThing decreased cellular glutamate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001570 biolink:NamedThing decreased cellular glutathione level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione (GSH) measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001602 biolink:NamedThing decreased level of substance in vacuole A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the vacuole is lower than normal. FYPO_relaxed.owl FYPO:0001605 biolink:NamedThing decreased level of substance in cytosol A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cytosol is lower than normal. FYPO_relaxed.owl FYPO:0001613 biolink:NamedThing decreased cellular aspartate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-aspartate measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0001644 biolink:NamedThing decreased cellular lithium level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of lithium ions measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0002234 biolink:NamedThing decreased cellular sterol ester level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more sterol esters measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0002320 biolink:NamedThing decreased cellular squalene level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of squalene measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0002321 biolink:NamedThing decreased cellular ergosterol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ergosterol measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0002323 biolink:NamedThing decreased cellular GGPP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of all-trans-geranylgeranyl diphosphate (GGPP) measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0002324 biolink:NamedThing decreased cellular lanosterol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of lanosterol measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0002326 biolink:NamedThing decreased cellular sterol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a sterol measured in a cell is lower than normal. A sterol is any natural product derived from the steroid skeleton and containing a hydroxy group in the 3 position, closely related to cholestan-3-ol. FYPO_relaxed.owl FYPO:0002628 biolink:NamedThing decreased level of substance in cell wall during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cell wall is lower than normal. FYPO_relaxed.owl FYPO:0002812 biolink:NamedThing decreased cellular glycerol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0002829 biolink:NamedThing decreased cellular phytochelatin level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phytochelatin measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0003127 biolink:NamedThing decreased cellular nitric oxide level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nitric oxide measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0003459 biolink:NamedThing decreased cellular trehalose level during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is lower than normal when the cell is subject to salt stress. FYPO_relaxed.owl FYPO:0003460 biolink:NamedThing decreased cellular trehalose level during cellular response to oxidative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is lower than normal when the cell is subject to oxidative stress. FYPO_relaxed.owl FYPO:0003985 biolink:NamedThing decreased cellular amino acid level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of an amino acid measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0004013 biolink:NamedThing decreased cell surface pyruvylated galactose level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 4,6-pyruvylated D-galactose (4,6-O-[(1R)-1-carboxyethylidene]-D-galactose) measured at the cell surface is lower than normal. The cell surface refers to the external part of the cell wall and/or plasma membrane. FYPO_relaxed.owl FYPO:0004150 biolink:NamedThing decreased cellular pyridoxamine 5'-phosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of pyridoxamine 5'-phosphate measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0004151 biolink:NamedThing decreased cellular pyridoxine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of pyridoxine measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0004556 biolink:NamedThing decreased cellular phosphatidylcholine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylcholine measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0005584 biolink:NamedThing decreased cellular diglyceride level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more diglycerides measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0005585 biolink:NamedThing decreased cellular triglyceride level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more triglycerides measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0005774 biolink:NamedThing decreased cellular magnesium level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of magnesium ions measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006144 biolink:NamedThing decreased cellular gluconate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of gluconate measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006401 biolink:NamedThing decreased cellular dNTP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more 2'-deoxyribonucleoside triphosphates (dNTPs) measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006695 biolink:NamedThing decreased cellular S-adenosyl-L-methionine level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of S-adenosyl-L-methionine (SAM) measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006699 biolink:NamedThing decreased cellular hercynylcysteine sulfoxide level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of hercynylcysteine sulfoxide measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006702 biolink:NamedThing decreased cellular adenine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of adenine measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006704 biolink:NamedThing decreased cellular sedoheptulose-7-phosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sedoheptulose-7-phosphate measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006705 biolink:NamedThing decreased cellular pentose phosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more pentose phosphates measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006881 biolink:NamedThing decreased cellular phytoceramide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phytoceramide measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006889 biolink:NamedThing decreased cellular iron level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of iron ion measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006969 biolink:NamedThing decreased cellular cytidine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cytidine measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006970 biolink:NamedThing decreased cellular bisphosphoglyceric acid level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of bisphosphoglyceric acid measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006971 biolink:NamedThing decreased cellular biotin level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of biotin measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006972 biolink:NamedThing decreased cellular S-adenosyl-L-cysteine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of S-adenosyl-L-cysteine measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006973 biolink:NamedThing decreased cellular L-glutamate methyl ester level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate methyl ester measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006978 biolink:NamedThing decreased cellular coenzyme Q10 level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of coenzyme Q10 measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0007187 biolink:NamedThing decreased cellular heme level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any heme measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0007291 biolink:NamedThing decreased cellular UDP-galactose level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of UDP-galactose measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0007365 biolink:NamedThing decreased cellular phosphoenolpyruvate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphoenolpyruvate measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0007917 biolink:NamedThing decreased cellular dihydroceramide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dihydroceramide measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0008024 biolink:NamedThing decreased cellular polyphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyphosphate measured in a cell (total or free) is lower than normal. FYPO_relaxed.owl FYPO:0008261 biolink:NamedThing decreased cellular mannosylinositol phosphorylceramide level A cell phenotype in which the amount of annosylinositol phosphorylceramide measured in a cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0008268 biolink:NamedThing decreased cellular phosphate (Pi) level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphate (Pi) measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0008280 biolink:NamedThing decreased cellular myo-inositol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of myo-inositol measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0003543 biolink:NamedThing increased number of double-strand break sites A cell phenotype in which the number of sites of double-strand breaks in DNA is greater than normal. FYPO_relaxed.owl FYPO:0003544 biolink:NamedThing increased number of double-strand break sites during meiotic cell cycle A cell phenotype in which the number of sites of double-strand breaks in DNA is greater than normal during a meiotic cell cycle. FYPO_relaxed.owl FYPO:0003547 biolink:NamedThing increased DNA damage during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage measured in a cell is greater than normal. The number, extent, or both of damage sites may be increased. FYPO_relaxed.owl FYPO:0003924 biolink:NamedThing increased DNA damage at stalled replication fork A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage measured at arrested replication forks in a cell is greater than normal. The number, extent, or both of damage sites may be increased. FYPO_relaxed.owl FYPO:0006591 biolink:NamedThing increased DNA damage during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage measured in a cell during S phase of the mitotic cell cycle is greater than normal. The number, extent, or both of damage sites may be increased. FYPO_relaxed.owl FYPO:0007329 biolink:NamedThing increased DNA damage at tRNA genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage measured at transfer RNA genes in a cell is greater than normal. The number, extent, or both of damage sites may be increased. FYPO_relaxed.owl FYPO:0007518 biolink:NamedThing increased transcription-induced DNA damage A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of DNA damage occurring as a side effect of transcription in a cell is greater than normal. The number, extent, or both of damage sites may be increased. FYPO_relaxed.owl FYPO:0006693 biolink:NamedThing decreased histone H3-K4 dimethylation during G0 A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 4 of histone H3 occurs to a lower extent than normal during G0 phase. FYPO_relaxed.owl FYPO:0006694 biolink:NamedThing decreased histone H3-K4 trimethylation during G0 A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 4 of histone H3 occurs to a lower extent than normal during G0 phase. FYPO_relaxed.owl FYPO:0006855 biolink:NamedThing abnormal histone H3-K37 methylation A cellular process phenotype in which methylation of lysine at position 37 of histone H3 is abnormal. FYPO_relaxed.owl FYPO:0007466 biolink:NamedThing abnormal histone H3-K9 methylation A cellular process phenotype in which methylation of lysine at position 9 of histone H3 is abnormal. FYPO_relaxed.owl FYPO:0000458 biolink:NamedThing abnormal histone H3-K9 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 is abnormal. FYPO_relaxed.owl FYPO:0000869 biolink:NamedThing increased histone methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation occurs to a greater extent than normal. All histone methylation may be affected, or methylation of specific sites on specific histones may be increased. FYPO_relaxed.owl FYPO:0000870 biolink:NamedThing decreased histone methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation occurs to a lower extent than normal. All histone methylation may be affected, or methylation of specific sites on specific histones may be decreased. FYPO_relaxed.owl FYPO:0002330 biolink:NamedThing abnormal histone H3-K4 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 4 of histone H3 is abnormal. FYPO_relaxed.owl FYPO:0002918 biolink:NamedThing abnormal histone H3-K36 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 36 of histone H3 is abnormal. FYPO_relaxed.owl FYPO:0004215 biolink:NamedThing abnormal histone H4-K20 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 20 of histone H4 is abnormal. FYPO_relaxed.owl FYPO:0007373 biolink:NamedThing abnormal histone methylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of histones in silent mating-type cassettes is abnormal. All histone methylation may be affected, or methylation of specific sites on specific histones may be altered. FYPO_relaxed.owl FYPO:0007374 biolink:NamedThing abnormal histone methylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of histones in centromeric regions is abnormal. All histone methylation may be affected, or methylation of specific sites on specific histones may be altered. FYPO_relaxed.owl FYPO:0007375 biolink:NamedThing abnormal histone methylation at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of histones in telomeric regions is abnormal. All histone methylation may be affected, or methylation of specific sites on specific histones may be altered. FYPO_relaxed.owl FYPO:0007467 biolink:NamedThing increased histone H3-K9 methylation during G0 A cellular process phenotype in which trimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal during G0 phase. FYPO_relaxed.owl FYPO:0000459 biolink:NamedThing abnormal mitotic centromeric sister chromatid cohesion A cellular process phenotype in which cohesion between centromeres of sister chromatids is abnormal during mitosis. FYPO_relaxed.owl FYPO:0007190 biolink:NamedThing increased sister chromatid cohesion along chromosome arms during mitotic interphase A cellular process phenotype in which cohesion between sister chromatids is increased along the length of the chromosome arms during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007209 biolink:NamedThing decreased sister chromatid cohesion along chromosome arms during mitotic interphase A cellular process phenotype in which cohesion between sister chromatids is decreased along the length of the chromosome arms during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007758 biolink:NamedThing increased duration of mitotic sister chromatid cohesion A cellular process phenotype in which mitotic sister chromatid cohesion lasts longer than normal, continuing into anaphase of mitosis. FYPO_relaxed.owl FYPO:0000460 biolink:NamedThing decreased mitotic centromeric sister chromatid cohesion A cellular process phenotype in which cohesion between centromeres of sister chromatids is decreased during mitosis. FYPO_relaxed.owl FYPO:0001056 biolink:NamedThing normal arginine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which L-arginine import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001559 biolink:NamedThing normal methionine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methionine import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002259 biolink:NamedThing normal leucine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which L-leucine import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002260 biolink:NamedThing normal glutamate import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which L-glutamate import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004848 biolink:NamedThing normal protein transport during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005574 biolink:NamedThing abnormal nuclear transport during meiosis A cellular process phenotype in which nuclear transport is abnormal during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0000470 biolink:NamedThing decreased mating type switching A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mating type switching is decreased. FYPO_relaxed.owl FYPO:0000471 biolink:NamedThing increased mating type switching A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mating type switching is increased. FYPO_relaxed.owl FYPO:0003659 biolink:NamedThing abnormal mating type switching resulting in duplication or deletion in mating-type region A cellular process phenotype observed in the vegetative growth phase of the life cycle in which all or part of the mating-type region is duplicated or deleted upon mating type switching. FYPO_relaxed.owl FYPO:0000473 biolink:NamedThing increased mitotic recombination A cellular process phenotype in which the occurrence of mitotic recombination is increased. FYPO_relaxed.owl FYPO:0000483 biolink:NamedThing increased rate of mitotic recombination A cellular process phenotype in which the rate, or speed, of mitotic recombination is increased. FYPO_relaxed.owl FYPO:0006280 biolink:NamedThing increased mitotic recombination with crossover formation at centromere A cellular process phenotype in which the occurrence of crossover formation as part of mitotic recombination is increased in centromeric regions. FYPO_relaxed.owl FYPO:0002224 biolink:NamedThing abnormally arrested meiotic cell cycle A cellular process phenotype in which progression through the meiotic cell cycle is arrested under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0003287 biolink:NamedThing abnormal cell cycle arrest in meiotic interphase before premeiotic DNA replication A cellular process phenotype in which progression through the meiotic cell cycle is arrested during the first meiotic interphase, before premeiotic DNA replication has taken place. FYPO_relaxed.owl FYPO:0000478 biolink:NamedThing normal meiosis A cellular process phenotype in which the meiotic nuclear divisions are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000573 biolink:NamedThing normal shmoo formation A cellular process phenotype in which mating projection assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000771 biolink:NamedThing normal nuclear pore localization A localization phenotype observed in the vegetative growth phase of the life cycle in which nuclear pore localization is normal (i.e. indistinguishable from wild type), resulting in a normal spatial arrangement of nuclear pores within the nuclear envelope. FYPO_relaxed.owl FYPO:0001216 biolink:NamedThing normal SAGA complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of a SAGA complex onto chromatin is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001278 biolink:NamedThing normal MCM complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which MCM complex assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002094 biolink:NamedThing normal meiotic sister chromatid cohesion A cellular process phenotype in which cohesion between sister chromatids is normal (i.e. indistinguishable from wild type) during meiosis. FYPO_relaxed.owl FYPO:0002448 biolink:NamedThing normal Dsc complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which Dsc E3 ubiquitin ligase complex assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002704 biolink:NamedThing normal autophagic vacuole docking A cellular process phenotype in which autophagic vacuole docking is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002826 biolink:NamedThing normal gamma-tubulin complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which gamma-tubulin complex assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002974 biolink:NamedThing normal origin recognition complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which origin recognition complex (ORC) assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003050 biolink:NamedThing normal homologous chromosome pairing A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type). Synapsis is the process in which the side by side pairing and physical juxtaposition of homologous chromosomes is established and maintained. Pairing may be assayed globally or at one or more specific loci. FYPO_relaxed.owl FYPO:0003176 biolink:NamedThing normal meiotic chromosome segregation A cellular process phenotype in which meiotic chromosome segregation is normal (i.e. indistinguishable from wild type). Meiotic chromosome segregation is the entire process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle. FYPO_relaxed.owl FYPO:0003541 biolink:NamedThing normal protein localization to meiotic spindle pole body A cell phenotype in which the localization of a protein to the meiotic spindle pole body is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003782 biolink:NamedThing normal nuclear pore localization during mitotic interphase A localization phenotype observed in the vegetative growth phase of the life cycle in which nuclear pore localization is normal (i.e. indistinguishable from wild type), resulting in a normal spatial arrangement of nuclear pores within the nuclear envelope, during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0003835 biolink:NamedThing normal horsetail movement A cellular process phenotype in which horsetail movement is normal (i.e. indistinguishable from wild type). Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I. FYPO_relaxed.owl FYPO:0004927 biolink:NamedThing normal prospore membrane formation A cellular process phenotype in which prospore formation assembly is normal (i.e. indistinguishable from wild type). In prospore formation, the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed. FYPO_relaxed.owl FYPO:0005221 biolink:NamedThing normal protein oligomerization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein oligomerization is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005322 biolink:NamedThing normal anaphase-promoting complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which anaphase-promoting complex assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005378 biolink:NamedThing normal spindle pole body organization A cell phenotype in which spindle pole body organization is normal (i.e. indistinguishable from wild type). Spindle pole body organization is a process that results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). FYPO_relaxed.owl FYPO:0005537 biolink:NamedThing normal telomerase holoenzyme complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomerase holoenzyme complex assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005538 biolink:NamedThing normal telomere-telomerase complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere-telomerase complex assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005783 biolink:NamedThing normal mitotic checkpoint complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic checkpoint complex assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006418 biolink:NamedThing normal resolution of meiotic recombination intermediates A cellular process phenotype in which the cleavage and rejoining of intermediates formed during meiotic recombination is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006426 biolink:NamedThing normal attachment of spindle microtubules to kinetochore during meiosis I A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during the first meiotic nuclear division is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006428 biolink:NamedThing normal mitotic sister chromatid biorientation A cellular process phenotype in which the stable attachment of sister chromatids to microtubules emanating from opposite poles of the mitotic spindle during metaphase plate congression is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006480 biolink:NamedThing normal cohesin loading A cell phenotype in which cohesin loading is normal (i.e. indistinguishable from wild type). Cohesin loading is the topological linking of a cohesin ring complex to chromatin. FYPO_relaxed.owl FYPO:0006726 biolink:NamedThing normal CMG complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which CMG complex assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006845 biolink:NamedThing normal histone methyltransferase activity (H3-K9 specific) activity A molecular function phenotype in which the observed rate of H3-K9 specific histone methyltransferase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006879 biolink:NamedThing normal cleavage furrow ingression A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cleavage furrow ingression is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007079 biolink:NamedThing normal initial meiotic spindle pole body separation in meiosis II A cellular process phenotype in which the initial release of duplicated spindle pole bodies that occurs as part of the second meiotic nuclear division, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007107 biolink:NamedThing normal microtubule cytoskeleton organization during meiosis I A cellular process phenotype in which microtubule cytoskeleton organization is normal (i.e. indistinguishable from wild type) during meiosis I. Microtubule cytoskeleton organization is the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. FYPO_relaxed.owl FYPO:0007109 biolink:NamedThing normal meiotic centromere clustering during meiotic prometaphase I A cellular process phenotype in which centromere clustering is normal (i.e. indistinguishable from wild type during meiotic prometaphase I. FYPO_relaxed.owl FYPO:0007205 biolink:NamedThing normal replication fork arrest at rDNA repeats A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at sites within the eukaryotic rDNA repeat spacer is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007225 biolink:NamedThing normal heterochromatin assembly by small RNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which assembly of heterochromatin mediated by small RNA is normal (i.e. indistinguishable from wild type). Small RNA-mediated heterochromatin assembly results in transcriptional silencing. FYPO_relaxed.owl FYPO:0007276 biolink:NamedThing normal mitochondrion inheritance during meiotic cell cycle A cellular process phenotype in which mitochondrion inheritance is normal (i.e. indistinguishable from wild type) during the meiotic cell cycle. Mitochondrion inheritance is a cellular process that results in the distribution of mitochondria into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton. FYPO_relaxed.owl FYPO:0007301 biolink:NamedThing normal protein aggregate center formation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein aggregate center formation is normal (i.e. indistinguishable from wild type). Protein aggregate centers are composed of chaperones and misfolded proteins, and are reversibly formed in the nucleus and cytosol to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding. FYPO_relaxed.owl FYPO:0007591 biolink:NamedThing normal mitophagy A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007666 biolink:NamedThing normal establishment or maintenance of actin cytoskeleton polarity during mating A cellular process phenotype in which the establishment or maintenance of actin cytoskeleton polarity is normal (i.e. indistinguishable from wild type) during conjugation with cellular fusion. FYPO_relaxed.owl FYPO:0007915 biolink:NamedThing normal endoplasmic reticulum localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which Endoplasmic Reticulum localization is normal. FYPO_relaxed.owl FYPO:0008108 biolink:NamedThing normal mitochondrial inheritance A phenotype in which mitochondrial is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007078 biolink:NamedThing normal meiotic cell cycle process A cellular process phenotype in which a cell executes a meiotic cell cycle process normally (i.e. indistinguishably from wild type). A meiotic cell cycle process is any of the processes that form part of the meiotic cell cycle, and thereby ensures successive accurate and complete genome replication and meiotic chromosome segregation. FYPO_relaxed.owl FYPO:0000590 biolink:NamedThing normal sporulation A cellular process phenotype in which ascospore formation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002043 biolink:NamedThing normal premeiotic DNA replication A cellular process phenotype in which premeiotic DNA replication is normal. FYPO_relaxed.owl FYPO:0003891 biolink:NamedThing normal intragenic meiotic recombination A cellular process phenotype in which the occurrence of intragenic meiotic recombination is normal (i.e. indistinguishable from wild type). Intragenic meiotic recombination can result in gene conversion events. FYPO_relaxed.owl FYPO:0005060 biolink:NamedThing normal meiotic DNA double-strand break resection A cellular process phenotype in which meiotic DNA double-strand break resection is normal (i.e. indistinguishable from wild type). Meiotic DNA double-strand break resection is the process by which long-tract single-stranded 3'-end DNA is generated by removal of bases from a 5' end from which SPO11/Rec12-oligonucleotide complexes have been removed. FYPO_relaxed.owl FYPO:0005578 biolink:NamedThing normal intergenic meiotic recombination A cellular process phenotype in which the occurrence of intergenic meiotic recombination is normal (i.e. indistinguishable from wild type). Intergenic meiotic recombination reflects crossovers between homologous chromosomes. FYPO_relaxed.owl FYPO:0005912 biolink:NamedThing normal meiosis-specific chromatin remodeling A cellular process phenotype in which chromatin remodeling that occurs as part of meiosis I is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005936 biolink:NamedThing normal intragenic meiotic recombination frequency A cellular process phenotype in which the frequency of occurrence of intragenic meiotic recombination is normal (i.e. indistinguishable from wild type). Intragenic meiotic recombination can result in gene conversion events. FYPO_relaxed.owl FYPO:0005941 biolink:NamedThing normal meiotic DNA double-strand break clipping A cellular process phenotype in which meiotic DNA double-strand break clipping is normal (i.e. indistinguishable from wild type). Meiotic DNA double-strand break clipping is the process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis. FYPO_relaxed.owl FYPO:0005942 biolink:NamedThing normal intergenic meiotic recombination frequency A cellular process phenotype in which the frequency of occurrence of intergenic meiotic recombination is normal (i.e. indistinguishable from wild type). Intergenic meiotic recombination reflects crossovers between homologous chromosomes. FYPO_relaxed.owl FYPO:0006389 biolink:NamedThing normal meiotic spindle pole body oscillation during prophase I A cellular process phenotype in which the meiotic spindle pole body (SPB) moves rapidly back and forth within the nuclear envelope to a normal (i.e. indistinguishable from wild type) extent during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0008078 biolink:NamedThing normal meiotic sister kinetochore association in meiotic metaphase I A cellular process phenotype in which meiotic sister kinetochore association in meiotic metaphase I, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008201 biolink:NamedThing normal meiotic cell cycle entry A cellular process phenotype in which a cell enters the meiotic cell cycle normally: i.e after conjugation with cellular fusion and karyogamy with nuclear fusion. FYPO_relaxed.owl FYPO:0000485 biolink:NamedThing decreased meiotic recombination A cellular process phenotype in which the occurrence of reciprocal meiotic recombination is decreased. FYPO_relaxed.owl FYPO:0000486 biolink:NamedThing delayed onset of meiotic recombination A cellular process phenotype in which reciprocal meiotic recombination begins later than normal. FYPO_relaxed.owl FYPO:0000487 biolink:NamedThing increased meiotic recombination A cellular process phenotype in which the occurrence of reciprocal meiotic recombination is increased. FYPO_relaxed.owl FYPO:0002486 biolink:NamedThing decreased meiotic strand displacement A cellular process phenotype in which the occurrence of meiotic strand displacement is decreased. Meiotic strand displacement is the part of meiotic recombination in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. FYPO_relaxed.owl FYPO:0003346 biolink:NamedThing abnormal meiotic recombination at silent mating-type cassette A cellular process phenotype in which reciprocal meiotic recombination is abnormal at the silent mating-type cassettes. Meiotic recombination is a cellular process in which double strand breaks are formed and repaired through a double Holliday junction intermediate, resulting in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. FYPO_relaxed.owl FYPO:0003564 biolink:NamedThing abnormal meiotic DNA double-strand break formation A cellular process phenotype in which generation of double-strand breaks at defined hotspots throughout the genome during meiosis I is abnormal. FYPO_relaxed.owl FYPO:0003615 biolink:NamedThing decreased meiotic DNA double-strand break formation A cellular process phenotype in which generation of double-strand breaks at defined hotspots throughout the genome during meiosis I is decreased. FYPO_relaxed.owl FYPO:0003792 biolink:NamedThing increased meiotic DNA double-strand break formation at silent mating-type cassette A cellular process phenotype in which generation of double-strand breaks at defined hotspots throughout the genome during meiosis I is increased at the silent mating-type cassettes. FYPO_relaxed.owl FYPO:0005057 biolink:NamedThing abolished meiotic DNA double-strand break clipping A cellular process phenotype in which meiotic DNA double-strand break clipping does not occur. Meiotic DNA double-strand break clipping is the process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis. FYPO_relaxed.owl FYPO:0005058 biolink:NamedThing decreased meiotic DNA double-strand break clipping A cellular process phenotype in which meiotic DNA double-strand break clipping is decreased. Meiotic DNA double-strand break clipping is the process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis. FYPO_relaxed.owl FYPO:0005059 biolink:NamedThing decreased meiotic DNA double-strand break resection A cellular process phenotype in which meiotic DNA double-strand break resection is decreased. Meiotic DNA double-strand break resection is the process by which long-tract single-stranded 3'-end DNA is generated by removal of bases from a 5' end from which SPO11/Rec12-oligonucleotide complexes have been removed. FYPO_relaxed.owl FYPO:0005658 biolink:NamedThing abnormal frequency of meiotic crossover associated with gene conversion A cellular process phenotype in which the frequency of crossover associated with a gene conversion event during meiotic recombination is abnormal. FYPO_relaxed.owl FYPO:0007238 biolink:NamedThing increased meiotic double crossover formation A cellular process phenotype in which the occurrence of two crossovers within a given interval during meiosis I is higher than normal. FYPO_relaxed.owl FYPO:0002713 biolink:NamedThing decreased DNA recombination at mating type locus A cellular process phenotype in which the occurrence of DNA recombination is decreased at the mating type locus. FYPO_relaxed.owl FYPO:0003775 biolink:NamedThing decreased transposon-derived cDNA recombination A cellular process phenotype in which the occurrence of DNA recombination between cDNAs derived from transposon-encoded genes is decreased. FYPO_relaxed.owl FYPO:0000490 biolink:NamedThing abnormal mitochondrial genome maintenance A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial genome maintenance is abnormal. FYPO_relaxed.owl FYPO:0004340 biolink:NamedThing abnormal mitochondrial fission A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission, the division of a mitochondrion into two or more separate compartments, is abnormal. FYPO_relaxed.owl FYPO:0000492 biolink:NamedThing decreased mitochondrial genome maintenance A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial genome maintenance is decreased. FYPO_relaxed.owl FYPO:0000493 biolink:NamedThing increased mitochondrial genome maintenance A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial genome maintenance is increased. FYPO_relaxed.owl FYPO:0000496 biolink:NamedThing decreased mitochondrial transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial transport is decreased. FYPO_relaxed.owl FYPO:0000515 biolink:NamedThing decreased nuclear import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of nuclear import is decreased. Nuclear import is the directed movement of any substance into the nucleus; import of all substances or a specific substance may be affected. FYPO_relaxed.owl FYPO:0000524 biolink:NamedThing decreased peroxisomal transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of peroxisomal transport is decreased. FYPO_relaxed.owl FYPO:0005526 biolink:NamedThing decreased transport along microtubule during vegetative growth A transport phenotype observed in the vegetative growth phase of the life cycle in which the transport of organelles or other particles along microtubules is decreased. FYPO_relaxed.owl FYPO:0006707 biolink:NamedThing decreased calcium ion transport from cytosol to endoplasmic reticulum A transport phenotype observed in the vegetative growth phase of the life cycle in which the movement of calcium ions from the cytosol to the endoplasmic reticulum is decreased. FYPO_relaxed.owl FYPO:0000497 biolink:NamedThing decreased rate of mitochondrial transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitochondrial transport is decreased. FYPO_relaxed.owl FYPO:0000498 biolink:NamedThing normal mitochondrial transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial transport is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001071 biolink:NamedThing normal transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transport is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001851 biolink:NamedThing normal ferrous iron import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ferrous iron import is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000500 biolink:NamedThing decreased mitophagy A cellular process phenotype in which the occurrence of mitophagy is decreased. FYPO_relaxed.owl FYPO:0000501 biolink:NamedThing increased mitophagy A cellular process phenotype in which the occurrence of mitophagy is increased. FYPO_relaxed.owl FYPO:0007593 biolink:NamedThing abnormal mitophagy during nitrogen starvation A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, is abnormal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0001217 biolink:NamedThing abnormal nuclear import A cellular process phenotype in which nuclear import is abnormal. Nuclear import is the directed movement of any substance out of the nucleus; import of all substances or a specific substance may be affected. FYPO_relaxed.owl FYPO:0000509 biolink:NamedThing normal nuclear export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear export is normal (i.e. indistinguishable from wild type). Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected. FYPO_relaxed.owl FYPO:0000516 biolink:NamedThing normal nuclear import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear import is normal (i.e. indistinguishable from wild type). Nuclear import is the directed movement of any substance into the nucleus; import of all substances or a specific substance may be affected. FYPO_relaxed.owl FYPO:0000513 biolink:NamedThing delayed onset of nuclear fusion during mating A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion begins later than normal. FYPO_relaxed.owl FYPO:0007162 biolink:NamedThing increased duration of nuclear fusion during mating A cellular process phenotype in which the duration of karyogamy involved in conjugation with cellular fusion is longer than normal. FYPO_relaxed.owl FYPO:0006890 biolink:NamedThing decreased heme export from vacuole A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of heme export from the vacuole to the cytoplasm is decreased. FYPO_relaxed.owl FYPO:0000519 biolink:NamedThing decreased oxidative phosphorylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidative phosphorylation is decreased. FYPO_relaxed.owl FYPO:0003394 biolink:NamedThing decreased mitochondrial electron transport, NADH to ubiquinone A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial electron transport from NADH to ubiquinone is decreased. FYPO_relaxed.owl FYPO:0004020 biolink:NamedThing decreased mitochondrial electron transport, succinate to ubiquinone A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial electron transport from succinate to ubiquinone is decreased. FYPO_relaxed.owl FYPO:0000520 biolink:NamedThing increased oxidative phosphorylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidative phosphorylation is increased. FYPO_relaxed.owl FYPO:0000984 biolink:NamedThing abnormal transcriptional response to pheromone A conjugation phenotype in which regulation of transcription in response to mating pheromone is abnormal. FYPO_relaxed.owl FYPO:0007120 biolink:NamedThing abolished cell cycle arrest in mitotic G1 phase in response to leucine starvation A cellular process phenotype in which the occurrence of cell cycle arrest in response to leucine starvation does not occur; arrest normally occurs in G1 phase. FYPO_relaxed.owl FYPO:0000532 biolink:NamedThing decreased mitotic cell cycle arrest in response to pheromone A cellular process phenotype in which the occurrence of mitotic cell cycle arrest in response to pheromone is decreased. FYPO_relaxed.owl FYPO:0004074 biolink:NamedThing delayed onset of cell cycle arrest in mitotic G1 phase in response to pheromone A cellular process phenotype in which the occurrence of cell cycle arrest in response to a pheromone occurs in G1 phase, but begins later than normal. FYPO_relaxed.owl FYPO:0007563 biolink:NamedThing cell cycle arrest in mitotic G1 phase in response to pheromone without starvation A cellular process phenotype in which the occurrence of cell cycle arrest in response to a pheromone occurs in G1 phase, but in the absence of starvation (i.e., in nutrient-rich conditions, under which wild-type fission yeast cells do not arrest). FYPO_relaxed.owl FYPO:0000533 biolink:NamedThing normal mitotic cell cycle arrest in response to pheromone A cellular process phenotype in which mitotic cell cycle arrest in response to pheromone is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001000 biolink:NamedThing normal cell cycle arrest in mitotic G1 phase during nitrogen starvation A cellular process phenotype in which progression through the mitotic cell cycle is arrested normally in G1 phase when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0001027 biolink:NamedThing normal cell cycle arrest at mitotic G2/M phase transition during glucose starvation A cellular process phenotype in which progression through the mitotic cell cycle is arrested normally at the mitotic G2/M phase transition when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0007089 biolink:NamedThing normal cell cycle arrest at mitotic G2/M phase transition during sulfur starvation A cellular process phenotype in which progression through the mitotic cell cycle is arrested normally at the mitotic G2/M phase transition when the cell is subject to sulfur starvation. FYPO_relaxed.owl FYPO:0000538 biolink:NamedThing decreased protein secretion during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein secretion is decreased. FYPO_relaxed.owl FYPO:0000539 biolink:NamedThing increased protein secretion during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein secretion is increased. FYPO_relaxed.owl FYPO:0001920 biolink:NamedThing decreased protein export from nucleus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein export from nucleus is decreased. Export of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003189 biolink:NamedThing decreased protein import into nucleus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein import into the nucleus is decreased. Import of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005494 biolink:NamedThing decreased protein transport along microtubule during vegetative growth A transport phenotype observed in the vegetative growth phase of the life cycle in which the transport of proteins along microtubules is decreased. Transport of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001179 biolink:NamedThing abolished protein localization during vegetative growth A cell phenotype in which a protein does not localize to, and is therefore absent from, a place where it is normally found in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0003839 biolink:NamedThing abnormal protein localization to nucleolus during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus is abnormal during mitotic nuclear division. FYPO_relaxed.owl FYPO:0005649 biolink:NamedThing increased duration of protein localization to telomere A cell phenotype observed in the vegetative growth phase of the life cycle in which the duration of localization of a protein to the telomere of a chromosome is longer than normal. FYPO_relaxed.owl FYPO:0005815 biolink:NamedThing abnormal protein localization to perinuclear region of cytoplasm during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the perinuclear region of the cytoplasm is abnormal during mitotic nuclear division. FYPO_relaxed.owl FYPO:0005992 biolink:NamedThing decreased protein localization to P-bodies A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to P-bodies is decreased. FYPO_relaxed.owl FYPO:0006098 biolink:NamedThing abnormal protein localization to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to all or part of the cytoplasm is abnormal. FYPO_relaxed.owl FYPO:0006360 biolink:NamedThing increased protein exchange at pericentric heterochromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of a protein in cis and trans between heterochromatin domains occurs to a greater extent than normal in regions of pericentric heterochromatin. FYPO_relaxed.owl FYPO:0006370 biolink:NamedThing decreased protein exchange at subtelomeric heterochromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of a protein in cis and trans between heterochromatin domains occurs to a lower extent than normal in regions of subtelomeric heterochromatin. FYPO_relaxed.owl FYPO:0006607 biolink:NamedThing abnormal intermittent protein localization to Cdr2 medial cortical node complex A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein that is normally localized intermittently to the Cdr2 medial cortical node complex shows an abnormal pattern of localization to the complex over time. FYPO_relaxed.owl FYPO:0006723 biolink:NamedThing decreased protein exit from Cdr2 medial cortical node complex during cellular response to osmotic stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein that normally moves away from Cdr2 medial cortical node complexes during a cellular response to osmotic stress instead remains predominantly in the nodes. FYPO_relaxed.owl FYPO:0007029 biolink:NamedThing decreased protein localization to polysome A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to polysomes is decreased. FYPO_relaxed.owl FYPO:0007784 biolink:NamedThing decreased protein localization to protein aggregate center A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to protein aggregate centers is decreased. Protein aggregate centers are composed of chaperones and misfolded proteins, and are reversibly formed in the nucleus and cytosol to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding. FYPO_relaxed.owl FYPO:0008184 biolink:NamedThing decreased protein localization to processome A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the processome is decreased. FYPO_relaxed.owl FYPO:0006503 biolink:NamedThing abnormal protein localization to actin fusion focus A cell phenotype in which the localization of a protein to the actin fusion focus is abnormal. FYPO_relaxed.owl FYPO:0002505 biolink:NamedThing decreased protein palmitoylation A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0002509 biolink:NamedThing increased protein palmitoylation A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0002495 biolink:NamedThing normal protein modification A cellular process phenotype in which protein modification is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002500 biolink:NamedThing normal protein palmitoylation A cellular process phenotype in which protein palmitoylation is normal (i.e. indistinguishable from wild type). Protein palmitoylation is the addition of a palmitoyl group to a protein amino acid. FYPO_relaxed.owl FYPO:0004422 biolink:NamedThing normal protein phosphorylation A cellular process phenotype in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006621 biolink:NamedThing normal H3-K4 deacetylation during recovery from glucose starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which deacetylation of lysine at position 4 of histone H3 is normal (i.e. indistinguishable from wild type) when the cell is returned to glucose-rich medium following glucose starvation. FYPO_relaxed.owl FYPO:0000550 biolink:NamedThing abnormal pseudohyphal growth A cellular process phenotype in which pseudohyphal growth is abnormal. FYPO_relaxed.owl FYPO:0004075 biolink:NamedThing decreased cell growth A cellular process phenotype in which cell growth is decreased. Cell growth is the irreversible increase in size over time by accretion and biosynthetic production of matter similar to that already present. FYPO_relaxed.owl FYPO:0006820 biolink:NamedThing abnormal cell growth rate A cellular process phenotype in which the rate of cell growth is abnormal. Cell growth is the irreversible increase in size over time by accretion and biosynthetic production of matter similar to that already present. FYPO_relaxed.owl FYPO:0000552 biolink:NamedThing decreased pseudohyphal growth A cellular process phenotype in which the occurrence of pseudohyphal growth is decreased. FYPO_relaxed.owl FYPO:0003776 biolink:NamedThing increased pseudohyphal growth A cellular process phenotype in which the occurrence of pseudohyphal growth is increased. FYPO_relaxed.owl FYPO:0004085 biolink:NamedThing decreased vegetative cell growth A cellular process phenotype in which cell growth is decreased during the vegetative growth phase of the life cycle. Cell growth is the irreversible increase in size over time by accretion and biosynthetic production of matter similar to that already present. FYPO_relaxed.owl FYPO:0000553 biolink:NamedThing increased pseudohyphal growth during cellular hyperosmotic response A cellular process phenotype in which the occurrence of pseudohyphal growth is increased during a cellular hyperosmotic response. FYPO_relaxed.owl FYPO:0000554 biolink:NamedThing normal pseudohyphal growth A cell population phenotype in which pseudohyphal growth is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002062 biolink:NamedThing normal cell growth A cellular process phenotype in which the growth of a cell is normal (i.e. indistinguishable from wild type). Cell growth is the process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. FYPO_relaxed.owl FYPO:0006819 biolink:NamedThing normal vegetative cell growth rate A cellular process phenotype in which cells elongate at a normal (i.e. indistinguishable from wild type) rate during the vegetative growth phase of the life cycle. Cell growth is the process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. FYPO_relaxed.owl FYPO:0000557 biolink:NamedThing decreased re-entry into mitotic cell cycle after pheromone arrest A cellular process phenotype in which the occurrence of re-entry into the mitotic cell cycle after pheromone arrest is decreased. FYPO_relaxed.owl FYPO:0000558 biolink:NamedThing increased re-entry into mitotic cell cycle after pheromone arrest A cellular process phenotype in which the occurrence of re-entry into the mitotic cell cycle after pheromone arrest is increased. FYPO_relaxed.owl FYPO:0000559 biolink:NamedThing increased rate of re-entry into mitotic cell cycle after pheromone arrest A cellular process phenotype in which the rate, or speed, of re-entry into the mitotic cell cycle after pheromone arrest is increased. FYPO_relaxed.owl FYPO:0000560 biolink:NamedThing normal re-entry into mitotic cell cycle after pheromone arrest A cellular process phenotype in which re-entry into the mitotic cell cycle after pheromone arrest is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006142 biolink:NamedThing normal G0 to G1 transition A cellular process phenotype in which the transition from G0 phase (quiescence) to G1 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000561 biolink:NamedThing normal mitotic G1 phase progression A cellular process phenotype in which progression through the G1 phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002740 biolink:NamedThing normal mitotic cell cycle phase A cellular process phenotype in which a cell proceeds normally through a specific mitotic cell cycle phase. A mitotic cell cycle phase is any of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events. FYPO_relaxed.owl FYPO:0001532 biolink:NamedThing normal duration of mitotic S phase A cell cycle phenotype in which the duration of S phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003246 biolink:NamedThing normal mitotic S phase progression A cellular process phenotype in which progression through S phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004310 biolink:NamedThing normal duration of mitotic M phase A cell cycle phenotype in which the duration of M phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004646 biolink:NamedThing normal duration of mitotic anaphase A cell cycle phenotype in which the duration of anaphase of mitosis normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005305 biolink:NamedThing normal duration of mitotic interphase A cell cycle phenotype in which the duration of interphase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006257 biolink:NamedThing normal duration of mitotic prophase A cell cycle phenotype in which the duration of prophase of mitosis normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000610 biolink:NamedThing abnormal mitotic S phase progression A cellular process phenotype in which progression through S phase of the mitotic cell cycle is abnormal. FYPO_relaxed.owl FYPO:0001070 biolink:NamedThing decreased duration of mitotic cell cycle phase A cellular process phenotype in which the duration of one or more mitotic cell cycle phases is shorter than normal. FYPO_relaxed.owl FYPO:0000570 biolink:NamedThing decreased shmoo formation A cellular process phenotype in which the occurrence of mating projection assembly is decreased. FYPO_relaxed.owl FYPO:0000571 biolink:NamedThing decreased rate of shmoo formation A cellular process phenotype in which the rate, or speed, of mating projection assembly is decreased. FYPO_relaxed.owl FYPO:0000572 biolink:NamedThing increased rate of shmoo formation A cellular process phenotype in which the rate, or speed, of mating projection assembly is increased. FYPO_relaxed.owl FYPO:0001867 biolink:NamedThing increased shmoo formation A cellular process phenotype in which the occurrence of mating projection assembly is increased. FYPO_relaxed.owl FYPO:0001873 biolink:NamedThing shmoo formation in absence of opposite mating type A cellular process phenotype in which mating projection assembly takes place despite the absence of cells of the opposite mating type. FYPO_relaxed.owl FYPO:0006011 biolink:NamedThing shmoo formation at cell side A cellular process phenotype in which mating projection assembly occurs along the lateral portion of the long axis of the cell instead of at one cell end. FYPO_relaxed.owl FYPO:0006108 biolink:NamedThing abnormal actin fusion focus assembly A cellular process phenotype in which actin fusion focus assembly is abnormal. An actin fusion focus normally forms during mating at the site where the two cells will fuse. FYPO_relaxed.owl FYPO:0006504 biolink:NamedThing multiple shmoo formation A cellular process phenotype in which a cell forms two or more shmoos, usually in succession, without fusing with a partner cell. Cell fusion may or may not subsequently occur. FYPO_relaxed.owl FYPO:0000579 biolink:NamedThing normal spore germination A cellular process phenotype in which spore germination is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003058 biolink:NamedThing normal RNA localization A cell phenotype in which the localization of an RNA in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003135 biolink:NamedThing normal agglutination A cell adhesion phenotype in which cells adhere to other cells of compatible mating type normally (i.e. agglutination is indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003627 biolink:NamedThing normal protein localization A cell phenotype in which the localization of a protein in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003845 biolink:NamedThing normal protein localization to prospore membrane A transport phenotype in which protein localization to the prospore membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004600 biolink:NamedThing normal transcriptional response to pheromone A conjugation phenotype in which regulation of transcription in response to mating pheromone is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004744 biolink:NamedThing normal heterochromatin maintenance involved in chromatin silencing at centromere outer repeat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin maintenance is normal (i.e. indistinguishable from wild type) in the context of chromatin silencing at centromere outer repeat regions. FYPO_relaxed.owl FYPO:0004973 biolink:NamedThing normal telomere localization A cellular process phenotype in which telomere localization, a process in which a telomere is transported to, and/or maintained in, a specific location, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005807 biolink:NamedThing normal protein movement within plasma membrane A cellular process phenotype in which the movement of one or more proteins within the plasma membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006052 biolink:NamedThing normal lipid droplet localization to prospore membrane leading edge A cellular process phenotype in which the localization of lipid droplets to the prospore membrane occurs to a normal (i.e. indistinguishable from wild type) extent. FYPO_relaxed.owl FYPO:0006764 biolink:NamedThing normal activation of meiotic cell cycle DNA replication checkpoint A cell cycle checkpoint phenotype in which the meiotic cell cycle DNA replication checkpoint is activated at a normal (i.e. indistinguishable from wild type) frequency, under conditions that cause checkpoint activation in wild-type cells. The meiotic DNA replication checkpoint delays the meiotic nuclear division until pre-meiotic DNA replication is complete. FYPO_relaxed.owl FYPO:0006839 biolink:NamedThing normal protein complex assembly A cellular process phenotype in which the assembly of a protein complex at the cellular level is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007277 biolink:NamedThing normal cellular process during meiotic cell cycle A phenotype in which a specific cellular process is normal (i.e. indistinguishable from wild type) in the meiotic cell cycle. FYPO_relaxed.owl FYPO:0007448 biolink:NamedThing normal reticulophagy during nitrogen starvation A cellular process phenotype in which autophagic degradation of the endoplasmic reticulum is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0008131 biolink:NamedThing normal growth site selection after cell division A phenotype in which the selection of the new growth site is at the old cell end . FYPO_relaxed.owl FYPO:0008136 biolink:NamedThing normal stop codon readthrough A metabolism phenotype observed in the vegetative growth phase of the life cycle in which translational readthough of a stop codon is normal (i.e. indistinguishable from wild-type) during cytoplasmic translation. FYPO_relaxed.owl FYPO:0000582 biolink:NamedThing decreased rate of spore germination A cellular process phenotype in which the rate, or speed, of spore germination is decreased. FYPO_relaxed.owl FYPO:0000593 biolink:NamedThing decreased transposition A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of transposition is decreased. FYPO_relaxed.owl FYPO:0000594 biolink:NamedThing increased transposition A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of transposition is increased. FYPO_relaxed.owl FYPO:0000595 biolink:NamedThing increased rate of transposition A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of transposition is increased. FYPO_relaxed.owl FYPO:0006104 biolink:NamedThing decreased retrotransposon integration A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of retrotransposon integration is decreased. FYPO_relaxed.owl FYPO:0003577 biolink:NamedThing abolished plasma membrane to vacuole transport after nitrogen starvation A cellular process phenotype in which the transport of a substance from the plasma membrane to the vacuole does not occur when the cell is subject to, or recovering from, nitrogen starvation. Transport normally occurs in two stages, plasma membrane to endosome followed by endosome to vacuole transport. FYPO_relaxed.owl FYPO:0000615 biolink:NamedThing decreased duration of mitotic S phase A cellular process phenotype in which the duration of progression through S phase of the mitotic cell cycle is shorter than normal. FYPO_relaxed.owl FYPO:0007072 biolink:NamedThing decreased duration of mitotic anaphase B A cellular process phenotype in which the duration of progression through anaphase B of mitosis is shorter than normal. Anaphase B is the stage of mitosis in which the polar microtubules elongate and the two poles of the spindle move farther apart. FYPO_relaxed.owl FYPO:0000619 biolink:NamedThing abnormal cell cycle arrest in mitotic anaphase A cellular process phenotype in which progression through the mitotic cell cycle is arrested in anaphase under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0000620 biolink:NamedThing abnormal cell cycle arrest in mitotic metaphase A cellular process phenotype in which progression through the mitotic cell cycle is arrested in metaphase under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0000622 biolink:NamedThing abnormal cell cycle arrest in mitotic telophase A cellular process phenotype in which progression through the mitotic cell cycle is arrested in telophase under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0003128 biolink:NamedThing inviable elongated mononucleate aseptate cell with cell cycle arrest in mitotic M phase A cell morphology phenotype in which a vegetative cell is inviable, contains one nucleus, has no septum, is elongated, and progression through the mitotic cell cycle is arrested in M phase. FYPO_relaxed.owl FYPO:0003145 biolink:NamedThing abnormal cell cycle arrest in mitotic prophase A cellular process phenotype in which progression through the mitotic cell cycle is arrested in prophase under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0003172 biolink:NamedThing abnormal cell cycle arrest in mitotic M phase without septation A cellular process phenotype in which progression through the mitotic cell cycle is arrested in M phase under conditions where arrest does not normally occur, and the cell does not form a septum. FYPO_relaxed.owl FYPO:0007647 biolink:NamedThing inviable elongated mononucleate aseptate cell with cell cycle arrest in mitotic M phase and normal nucleus localization A cell morphology phenotype in which a vegetative cell is inviable, contains one nucleus in the normal location, has no septum, and progression through the mitotic cell cycle is arrested in M phase. FYPO_relaxed.owl FYPO:0000623 biolink:NamedThing abnormal positive regulation of transcription A transcription regulation phenotype in which any process of positive regulation of transcription is abnormal. FYPO_relaxed.owl FYPO:0004276 biolink:NamedThing abnormal negative regulation of transcription during G0 A transcription regulation phenotype in which any process of negative regulation of transcription is abnormal during G0 phase. FYPO_relaxed.owl FYPO:0004305 biolink:NamedThing abnormal CTD phosphatase activity A molecular function phenotype in which the observed rate of CTD phosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0005089 biolink:NamedThing abolished RNA polymerase II carboxy-terminal domain kinase activity A molecular function phenotype in which RNA polymerase II carboxy-terminal domain kinase activity is absent. FYPO_relaxed.owl FYPO:0006675 biolink:NamedThing reversed parental genome-dependent asymmetric transcription A transcription regulation phenotype observed during conjugation in which a pattern of transcriptional regulation that normally differs between parental genomes has the opposite parental specificity compared to normal. For example, a gene that is normally transcribed first from the P (h+) parental genome is instead transcribed from the M (h-) genome earlier. FYPO_relaxed.owl FYPO:0000640 biolink:NamedThing abnormal chromatin silencing at centromere central core A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is abnormal at the centromere central core. Chromatin silencing is the observed effect of processes that repress transcription at the centromere central core, which is normally assembled into CENP-A-containing chromatin. FYPO_relaxed.owl FYPO:0006444 biolink:NamedThing abnormal transcriptional response to amino acid starvation A conjugation phenotype in which regulation of transcription in response to starvation for one or more amino acids is abnormal. FYPO_relaxed.owl FYPO:0007481 biolink:NamedThing attenuated increase in transcription during cellular response to stress in presence of small molecule A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an increase in the transcription of one or more target genes that would normally occur when cells are subjected to a stress in the presence of a specific small molecule occurs to a lower extent than normal under the same circumstances. FYPO_relaxed.owl FYPO:0000626 biolink:NamedThing abnormal initiation of premeiotic DNA replication A cellular process phenotype in which the initiation of premeiotic DNA replication is abnormal. FYPO_relaxed.owl FYPO:0001344 biolink:NamedThing abnormal mitotic DNA replication initiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication is abnormal. FYPO_relaxed.owl FYPO:0004628 biolink:NamedThing delayed onset of premeiotic DNA replication A cellular process phenotype in which premeiotic DNA replication begins later than normal. FYPO_relaxed.owl FYPO:0000632 biolink:NamedThing mitochondrial translation phenotype A cellular process phenotype that affects mitochondrial translation. FYPO_relaxed.owl FYPO:0003124 biolink:NamedThing abnormal cytoplasmic translation A metabolism phenotype observed in the vegetative growth phase of the life cycle in which translation in the cytoplasm is abnormal. Translation is the synthesis of a protein using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. FYPO_relaxed.owl FYPO:0000934 biolink:NamedThing abolished protein localization to microtubule cytoskeleton during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton does not occur. FYPO_relaxed.owl FYPO:0000938 biolink:NamedThing abolished protein localization to cortical microtubule cytoskeleton during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical microtubule cytoskeleton during interphase of the mitotic cell cycle does not occur. FYPO_relaxed.owl FYPO:0003277 biolink:NamedThing abolished protein localization to microtubule during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more microtubules does not occur during mitosis. FYPO_relaxed.owl FYPO:0004419 biolink:NamedThing abolished protein localization to cytoplasm with increased protein localization to nucleus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is abolished, and the protein is instead present in the nucleus at a greater level than normal. FYPO_relaxed.owl FYPO:0004472 biolink:NamedThing abolished protein localization to cytoplasm with protein mislocalized to nucleolus during cellular response to latrunculin B A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is abolished, and the protein is instead present in the nucleolus, during a cellular response to latrunculin B. FYPO_relaxed.owl FYPO:0004754 biolink:NamedThing abolished protein localization to mitotic spindle during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle does not occur during mitosis. FYPO_relaxed.owl FYPO:0005346 biolink:NamedThing abolished protein localization to cytoplasm, with protein mislocalized to nucleus during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is abolished, and the protein is instead present in the nucleus, during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006220 biolink:NamedThing abolished protein localization to septum A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell septum does not occur. FYPO_relaxed.owl FYPO:0006721 biolink:NamedThing abolished protein localization to Cdr2 medial cortical node complex A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Cdr2 medial cortical node complex does not occur. FYPO_relaxed.owl FYPO:0006825 biolink:NamedThing abolished protein localization to mitotic spindle pole body during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body does not occur during mitosis. FYPO_relaxed.owl FYPO:0001508 biolink:NamedThing abolished protein localization to chromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is abolished. FYPO_relaxed.owl FYPO:0003109 biolink:NamedThing abolished protein localization to telomere during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the telomere of a chromosome does not occur. FYPO_relaxed.owl FYPO:0003486 biolink:NamedThing abolished protein localization to double-strand break site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the region of a chromosome at which a DNA double-strand break has occurred is abolished. FYPO_relaxed.owl FYPO:0000636 biolink:NamedThing increased cell population growth rate A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal. FYPO_relaxed.owl FYPO:0003938 biolink:NamedThing increased cell population growth during glucose starvation A cell growth phenotype in which cell population growth is increased relative to normal under conditions of glucose starvation. FYPO_relaxed.owl FYPO:0004557 biolink:NamedThing increased vegetative cell population growth A cell growth phenotype in which vegetative cell population growth is increased relative to normal. Increased growth may reflect an increased growth rate (i.e. faster growth), growth that occurs to a greater extent than normal, or both. FYPO_relaxed.owl FYPO:0000637 biolink:NamedThing increased cell population growth rate on glucose carbon source A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal in a medium containing glucose as the carbon source. FYPO_relaxed.owl FYPO:0001157 biolink:NamedThing increased cell population growth rate at high pH A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal in a medium with higher than standard pH. Standard S. pombe growth media are approximately pH 5.6. FYPO_relaxed.owl FYPO:0007370 biolink:NamedThing increased cell population growth rate on fructose carbon source A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal in a medium containing fructose as the carbon source. FYPO_relaxed.owl FYPO:0007371 biolink:NamedThing increased cell population growth rate on sucrose carbon source A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal in a medium containing sucrose as the carbon source. FYPO_relaxed.owl FYPO:0007906 biolink:NamedThing increased cell population growth rate during amino acid starvation A cell population phenotype in which a cell population in the vegetative growth phase of the life cycle grows at a faster rate than normal during amino acid starvation. FYPO_relaxed.owl FYPO:0004167 biolink:NamedThing increased cell population growth on glycerol carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing glycerol as the carbon source. FYPO_relaxed.owl FYPO:0005243 biolink:NamedThing increased cell population growth on glutamine nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing glutamine as the nitrogen source. FYPO_relaxed.owl FYPO:0005245 biolink:NamedThing increased cell population growth on arabinose carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing arabinose as the carbon source. FYPO_relaxed.owl FYPO:0005247 biolink:NamedThing increased cell population growth on melibiose carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing melibiose as the carbon source. FYPO_relaxed.owl FYPO:0005258 biolink:NamedThing increased cell population growth at high temperature A cell population phenotype in which the growth of a population of cells is increased relative to normal in the vegetative growth phase of the life cycle at high temperatures. FYPO_relaxed.owl FYPO:0005260 biolink:NamedThing increased cell population growth at low temperature A vegetative cell population growth phenotype in which cell growth is increased relative to normal at a low temperature. FYPO_relaxed.owl FYPO:0005261 biolink:NamedThing increased cell population growth on galactose carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing galactose as the carbon source. FYPO_relaxed.owl FYPO:0005262 biolink:NamedThing increased cell population growth on maltose carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing maltose as the carbon source. FYPO_relaxed.owl FYPO:0006234 biolink:NamedThing increased cell population growth on gluconate carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing gluconate as the carbon source. FYPO_relaxed.owl FYPO:0007685 biolink:NamedThing increased vegetative cell population growth during nutrient starvation A cell growth phenotype in which vegetative cell population growth is increased relative to normal under conditions of starvation for one or more nutrients. FYPO_relaxed.owl FYPO:0008115 biolink:NamedThing increased cell population growth on sorbitol carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing sorbitol as the carbon source. FYPO_relaxed.owl FYPO:0008213 biolink:NamedThing increased vegetative cell population growth on lactate carbon source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing lactate as the carbon source. FYPO_relaxed.owl FYPO:0009024 biolink:NamedThing increased cell population growth on cysteine nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing cysteine as the nitrogen source. FYPO_relaxed.owl FYPO:0009025 biolink:NamedThing increased cell population growth on isoleucine nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing isoleucine as the nitrogen source. FYPO_relaxed.owl FYPO:0009026 biolink:NamedThing increased cell population growth on methionine nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing methionine as the nitrogen source. FYPO_relaxed.owl FYPO:0009027 biolink:NamedThing increased cell population growth on phenylalanine nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing phenylalanine as the nitrogen source. FYPO_relaxed.owl FYPO:0009028 biolink:NamedThing increased cell population growth on proline nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing proline as the nitrogen source. FYPO_relaxed.owl FYPO:0009029 biolink:NamedThing increased cell population growth on arginine nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing arginine as the nitrogen source. FYPO_relaxed.owl FYPO:0009051 biolink:NamedThing increased cell population growth on ammonium nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing ammonium as the nitrogen source. FYPO_relaxed.owl FYPO:0009052 biolink:NamedThing increased cell population growth on glutamate nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing glutamate as the nitrogen source. FYPO_relaxed.owl FYPO:0009072 biolink:NamedThing increased cell population growth on lysine nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing lysine as the nitrogen source. FYPO_relaxed.owl FYPO:0009074 biolink:NamedThing increased cell population growth on serine nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing serine as the nitrogen source. FYPO_relaxed.owl FYPO:0009076 biolink:NamedThing increased cell population growth on sucrose carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing sucrose as the carbon source. FYPO_relaxed.owl FYPO:0009077 biolink:NamedThing increased cell population growth on ethanol carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing ethanol as the carbon source. FYPO_relaxed.owl FYPO:0009093 biolink:NamedThing increased cell population growth on lysine and serine nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing lysine and serine as the nitrogen sources. FYPO_relaxed.owl FYPO:0009094 biolink:NamedThing increased cell population growth on lysine and proline nitrogen source A vegetative cell population phenotype in which cell growth is increased relative to normal in a medium containing lysine and proline as the nitrogen sources. FYPO_relaxed.owl FYPO:0009095 biolink:NamedThing increased cell population growth on fructose carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing fructose as the carbon source. FYPO_relaxed.owl FYPO:0009096 biolink:NamedThing increased cell population growth on xylose carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing xylose as the carbon source. FYPO_relaxed.owl FYPO:0009098 biolink:NamedThing increased cell population growth on mannitol carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing mannitol as the carbon source. FYPO_relaxed.owl FYPO:0009101 biolink:NamedThing increased cell population growth on glycerol and galactose carbon source A vegetative cell population growth phenotype in which cell growth is increased relative to normal in a medium containing glycerol and galactose carbon sources. FYPO_relaxed.owl FYPO:0003626 biolink:NamedThing normal protein localization to shmoo tip A cell phenotype in which the localization of a protein to the tip of a shmoo, or mating projection, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004095 biolink:NamedThing normal protein localization during meiotic cell cycle A cell phenotype in which the localization of a protein in a cell is normal (i.e. indistinguishable from wild type) during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0004096 biolink:NamedThing normal protein localization to cytoskeleton A cell phenotype in which the localization of a protein to the cytoskeleton is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004181 biolink:NamedThing normal protein localization to cell-cell contact point during mating A cell phenotype in which the localization of a protein to the region of contact between two cells undergoing conjugation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004997 biolink:NamedThing normal protein localization to chromosome A cell phenotype in which the localization of a protein to a region in a chromosome is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005747 biolink:NamedThing normal protein transport A cellular process phenotype in which protein transport is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006385 biolink:NamedThing normal protein localization to cell tip during nitrogen starvation A cell phenotype in which the localization of a protein to the cell tip is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006553 biolink:NamedThing normal protein localization to nucleus A cell phenotype in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006876 biolink:NamedThing normal protein localization to cell cortex of cell tip A cell phenotype in which the localization of a protein to the cell cortex of the cell tip is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007705 biolink:NamedThing normal protein localization to lateral cell cortex during glucose starvation A cell phenotype in which the localization of a protein to the cell cortex is normal (i.e. indistinguishable from wild type) when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0007865 biolink:NamedThing normal protein localization to spindle A cell phenotype in which the localization of a protein to the mitotic or meiotic spindle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008003 biolink:NamedThing normal protein localization to site of mechanical stress A cell phenotype in which the localization of a protein at a site of mechanical stress on the cell surface is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008002 biolink:NamedThing cell lysis during mating An inviable phenotype observed during mating in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost, during the process of cell fusion that occurs during mating. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised. FYPO_relaxed.owl FYPO:0008029 biolink:NamedThing cell lysis during hyphal growth phase An inviable phenotype observed during fungal hyphal growth phase in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. FYPO_relaxed.owl FYPO:0004531 biolink:NamedThing inviable after spore germination, single or double cell division, small cell A phenotype in which a spore germinates to produce a cell that is smaller than normal and undergoes one or two rounds of cell division. FYPO_relaxed.owl FYPO:0001491 biolink:NamedThing viable vegetative cell A cell phenotype in which a vegetatively growing cell is viable. FYPO_relaxed.owl FYPO:0002104 biolink:NamedThing viable vegetative cell with normal cell shape A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal shape and is viable. FYPO_relaxed.owl FYPO:0007665 biolink:NamedThing viable mononucleate monoseptate vegetative cell with anucleate compartment A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, and contains one nucleus and one septum. The septum divides the cell into two compartments, one of which contains the nucleus. FYPO_relaxed.owl FYPO:0000653 biolink:NamedThing DNA binding phenotype A phenotype that affects DNA binding. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001092 biolink:NamedThing binding phenotype A phenotype that affects the binding of a gene product to another substance. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0000702 biolink:NamedThing protein-protein interaction phenotype A phenotype that protein affects the binding of one protein to another. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0001527 biolink:NamedThing normal GTP binding A molecular function phenotype in which occurrence of GTP binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001528 biolink:NamedThing abnormal GTP binding A molecular function phenotype in which occurrence of GTP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001670 biolink:NamedThing abnormal GDP binding A molecular function phenotype in which occurrence of GDP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001708 biolink:NamedThing normal iron-sulfur cluster binding A molecular function phenotype in which occurrence of iron-sulfur cluster binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001709 biolink:NamedThing abnormal iron-sulfur cluster binding A molecular function phenotype in which occurrence of iron-sulfur cluster binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001863 biolink:NamedThing abolished leptomycin B binding A molecular function phenotype in which leptomycin B binding by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002131 biolink:NamedThing protein-RNA interaction phenotype A phenotype that affects an interaction between a protein and RNA. One of the relevant gene product may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0002245 biolink:NamedThing abnormal monosaccharide binding A molecular function phenotype in which occurrence of monosaccharide binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002306 biolink:NamedThing abnormal 5-phosphoribose 1-diphosphate binding A molecular function phenotype in which occurrence of 5-phosphoribose 1-diphosphate binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002308 biolink:NamedThing abnormal IMP binding A molecular function phenotype in which occurrence of IMP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002310 biolink:NamedThing abnormal GMP binding A molecular function phenotype in which occurrence of GMP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002388 biolink:NamedThing abnormal riboflavin binding A molecular function phenotype in which occurrence of riboflavin binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003375 biolink:NamedThing normal ubiquinone binding A molecular function phenotype in which occurrence of ubiquinone binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003391 biolink:NamedThing abnormal ubiquinone binding A molecular function phenotype in which occurrence of ubiquinone binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003637 biolink:NamedThing abnormal ADP binding A molecular function phenotype in which occurrence of ADP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003671 biolink:NamedThing abnormal ATP binding A molecular function phenotype in which occurrence of ATP binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003673 biolink:NamedThing normal ATP binding A molecular function phenotype in which occurrence of ATP binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003882 biolink:NamedThing increased cyclosporin A binding A molecular function phenotype in which occurrence of cyclosporin A binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003883 biolink:NamedThing increased sanglifehrin A binding A molecular function phenotype in which occurrence of sanglifehrin A binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0004499 biolink:NamedThing abnormal DNA polymerase processivity factor activity A molecular function phenotype in which the rate or occurrence of DNA polymerase processivity factor activity is abnormal. FYPO_relaxed.owl FYPO:0004501 biolink:NamedThing normal DNA polymerase processivity factor activity A molecular function phenotype in which the rate and occurrence of DNA polymerase processivity factor activity are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004698 biolink:NamedThing decreased heme binding A molecular function phenotype in which occurrence of heme binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005656 biolink:NamedThing abolished iron ion binding A molecular function phenotype in which iron ion binding by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006333 biolink:NamedThing decreased zinc ion binding A molecular function phenotype in which occurrence of zinc ion binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006435 biolink:NamedThing increased FAD binding A molecular function phenotype in which occurrence of FAD binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006942 biolink:NamedThing normal lipid binding A molecular function phenotype in which occurrence of lipid binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007168 biolink:NamedThing abolished microtubule attachment to cell cortex A cell phenotype in which the attachment of microtubules to the cell cortex does not occur. FYPO_relaxed.owl FYPO:0007250 biolink:NamedThing abnormal lipid binding A molecular function phenotype in which occurrence of lipid binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007525 biolink:NamedThing decreased ribosome binding A molecular function phenotype in which occurrence of ribosome binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007767 biolink:NamedThing decreased thiabendazole binding A molecular function phenotype in which occurrence of thiabendazole binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0008180 biolink:NamedThing decreased RNA polymerase II CTD binding A molecular function phenotype in which binding by a gene product to the RNA polymerase II CTD domain is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0008182 biolink:NamedThing decreased Spt5-CTD binding A molecular function phenotype in which binding by a gene product to the Spt5 CTD domain is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0000654 biolink:NamedThing catalytic activity phenotype A phenotype that affects a catalytic activity. FYPO_relaxed.owl FYPO:0007690 biolink:NamedThing catalytic activity regulator phenotype A phenotype that affects a molecular function which in turn binds to an enzyme and thereby directly regulates its catalytic activity. FYPO_relaxed.owl FYPO:0000655 biolink:NamedThing normal DNA binding A molecular function phenotype in which occurrence of DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0000656 biolink:NamedThing abnormal DNA binding A molecular function phenotype in which occurrence of DNA binding by a gene product is abnormal, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0000660 biolink:NamedThing normal catalytic activity A molecular function phenotype in which the observed rate and other catalytic properties of a specified catalytic activity are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000703 biolink:NamedThing normal protein-protein interaction A molecular function phenotype in which the binding of one protein to another is normal (i.e. indistinguishable from wild type). The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0002115 biolink:NamedThing normal transmembrane transporter activity A molecular function phenotype in which the observed rate of a specified transmembrane transporter activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002357 biolink:NamedThing normal protein-RNA interaction A molecular function phenotype in which an interaction between a protein and RNA is normal (i.e. indistinguishable from wild type). One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0007691 biolink:NamedThing normal DNA strand exchange activator activity A molecular function phenotype in which the activity of a DNA strand exchange activator is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007695 biolink:NamedThing normal DNA strand exchange inhibitor activity A molecular function phenotype in which the activity of a DNA strand exchange inhibitor is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007806 biolink:NamedThing normal endodeoxyribonuclease activator activity A molecular function phenotype in which the activity of a endodeoxyribonuclease activator is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008207 biolink:NamedThing normal microfilament motor activity A molecular function phenotype in which the observed rate or other property of a microfilament motor activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000661 biolink:NamedThing abnormal catalytic activity A molecular function phenotype in which the observed rate or other catalytic property of a specified catalytic activity is abnormal. FYPO_relaxed.owl FYPO:0000704 biolink:NamedThing abnormal protein-protein interaction A molecular function phenotype in which the binding of one protein to another is abnormal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0002132 biolink:NamedThing abnormal protein-RNA interaction A molecular function phenotype in which an interaction between a protein and RNA is abnormal. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0003591 biolink:NamedThing abnormal protein complex binding A molecular function phenotype in which the binding of one protein to a protein complex is abnormal. The protein whose binding to the protein complex is affected may be encoded by the mutated gene, or may be encoded by a different gene. FYPO_relaxed.owl FYPO:0005351 biolink:NamedThing increased guanyl-nucleotide exchange factor activity A molecular function phenotype in which the observed rate or other property of a guanyl-nucleotide exchange factor activity is abnormal. FYPO_relaxed.owl FYPO:0005446 biolink:NamedThing abolished molecular function A phenotype in which a specific molecular function is absent. FYPO_relaxed.owl FYPO:0006093 biolink:NamedThing abnormal microfilament motor activity A molecular function phenotype in which the observed rate or other property of a microfilament motor activity is abnormal. FYPO_relaxed.owl FYPO:0008030 biolink:NamedThing abnormal blue light photoreceptor activity A phenotype in which a blue light photoreceptor activity is abnormal. FYPO_relaxed.owl FYPO:0000657 biolink:NamedThing increased DNA binding A molecular function phenotype in which occurrence of DNA binding by a gene product is increased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0000658 biolink:NamedThing decreased DNA binding A molecular function phenotype in which occurrence of DNA binding by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0000659 biolink:NamedThing abolished DNA binding A molecular function phenotype in which DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003735 biolink:NamedThing altered DNA binding specificity A molecular function phenotype in which a gene product that normally binds to a specific DNA sequence instead binds to a different sequence when a gene is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005438 biolink:NamedThing abnormal DNA/DNA annealing activity A molecular function phenotype in which the observed rate of DNA/DNA annealing activity is abnormal. FYPO_relaxed.owl FYPO:0006555 biolink:NamedThing abnormal multiple protein binding to DNA A molecular function phenotype in which the binding of two or more proteins to DNA is abnormal. The proteins may bind simultaneously or sequentially, but both or all would normally be present together on DNA at some time. One affected gene product may be encoded by the mutated gene, or all may be encoded by different genes. FYPO_relaxed.owl FYPO:0000664 biolink:NamedThing abolished catalytic activity A molecular function phenotype in which a specified catalytic activity is absent. FYPO_relaxed.owl FYPO:0000705 biolink:NamedThing abolished protein-protein interaction A molecular function phenotype in which the binding of one protein to another does not occur. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0001093 biolink:NamedThing abolished chromatin binding A molecular function phenotype in which chromatin binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0002117 biolink:NamedThing abolished transporter activity A molecular function phenotype in which a specified transporter activity is absent. FYPO_relaxed.owl FYPO:0002133 biolink:NamedThing abolished protein-RNA interaction A molecular function phenotype in which an interaction between a protein and RNA does not occur. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0002785 biolink:NamedThing abolished riboflavin binding A molecular function phenotype in which riboflavin binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003297 biolink:NamedThing abolished ribosome binding A molecular function phenotype in which ribosome binding by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003633 biolink:NamedThing abolished U1 snRNP binding A molecular function phenotype in which U1 snRNP binding by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003635 biolink:NamedThing abolished U2 snRNP binding A molecular function phenotype in which U2 snRNP binding by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003672 biolink:NamedThing abolished ATP binding A molecular function phenotype in which ATP binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005143 biolink:NamedThing abolished proteasome core complex binding A molecular function phenotype in which proteasome core complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005145 biolink:NamedThing abolished proteasome regulatory particle binding A molecular function phenotype in which proteasome regulatory particle binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005234 biolink:NamedThing abolished MCM complex binding A molecular function phenotype in which MCM complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005418 biolink:NamedThing abolished ATPase activator activity A molecular function phenotype in which a gene product (usually a protein) that normally has ATPase activator activity has no activity in a mutant. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005861 biolink:NamedThing abolished CCR4-NOT complex binding A molecular function phenotype in which CCR4-NOT complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005862 biolink:NamedThing abolished MTREC complex binding A molecular function phenotype in which MTREC complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006937 biolink:NamedThing abolished lipid binding A molecular function phenotype in which lipid binding by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007070 biolink:NamedThing abolished NLS binding A molecular function phenotype in which binding to a nuclear localization sequence (NLS) in a protein by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007597 biolink:NamedThing abolished CLRC complex binding A molecular function phenotype in which CLRC complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007884 biolink:NamedThing abolished Lsm2-8 complex binding A molecular function phenotype in which Lms2-8 complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0008290 biolink:NamedThing abolished guanyl-nucleotide exchange factor activity A molecular function phenotype in which a guanyl-nucleotide exchange factor activity is absent. FYPO_relaxed.owl FYPO:0000683 biolink:NamedThing constitutive catalytic activity A regulation phenotype in which the basal activity of an enzyme is increased relative to normal. Basal enzyme activity is the activity observed in the absence of a regulator. Abnormally elevated basal activity may or may not reach the levels observed in the normal activated state. FYPO_relaxed.owl FYPO:0000663 biolink:NamedThing decreased catalytic activity A molecular function phenotype in which the observed rate of a specified catalytic activity is decreased. FYPO_relaxed.owl FYPO:0000666 biolink:NamedThing abnormal peptidase activity A molecular function phenotype in which the observed rate of a peptidase activity is abnormal. FYPO_relaxed.owl FYPO:0000687 biolink:NamedThing abnormal peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity A molecular function phenotype in which the observed rate of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity is abnormal. FYPO_relaxed.owl FYPO:0000689 biolink:NamedThing abnormal oxidoreductase activity A molecular function phenotype in which the observed rate of an oxidoreductase activity is abnormal. FYPO_relaxed.owl FYPO:0000720 biolink:NamedThing abnormal fatty acid synthase activity A molecular function phenotype in which the observed rate of fatty acid synthase activity is abnormal. FYPO_relaxed.owl FYPO:0000754 biolink:NamedThing abnormal glutathione gamma-glutamylcysteinyltransferase activity A molecular function phenotype in which the observed rate of glutathione gamma-glutamylcysteinyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0000917 biolink:NamedThing abnormal citrate (Si)-synthase activity A molecular function phenotype in which the observed rate of citrate (Si)-synthase activity is abnormal. FYPO_relaxed.owl FYPO:0000920 biolink:NamedThing abnormal aconitate hydratase activity A molecular function phenotype in which the observed rate of aconitate hydratase (also known as aconitase) activity is abnormal. FYPO_relaxed.owl FYPO:0001039 biolink:NamedThing abnormal thiamine diphosphokinase activity A molecular function phenotype in which the observed rate of thiamine diphosphokinase activity is abnormal. FYPO_relaxed.owl FYPO:0001087 biolink:NamedThing abnormal glucosyltransferase activity A molecular function phenotype in which the observed rate of a glucosyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0001167 biolink:NamedThing abnormal ATPase activity A molecular function phenotype in which the observed rate of ATPase activity is abnormal. FYPO_relaxed.owl FYPO:0001183 biolink:NamedThing abnormal alpha-glucosidase activity A molecular function phenotype in which the observed rate of an alpha-glucosidase activity is abnormal. FYPO_relaxed.owl FYPO:0001291 biolink:NamedThing abnormal CDP-diacylglycerol-serine O-phosphatidyltransferase activity A molecular function phenotype in which the observed rate of CDP-diacylglycerol-serine O-phosphatidyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0001381 biolink:NamedThing abnormal protein kinase activity A molecular function phenotype in which the observed rate of a protein kinase activity is abnormal. FYPO_relaxed.owl FYPO:0001476 biolink:NamedThing abnormal guanosine-diphosphatase activity A molecular function phenotype in which the observed rate of guanosine-diphosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0001479 biolink:NamedThing abnormal alpha,alpha-trehalase activity A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is abnormal. FYPO_relaxed.owl FYPO:0001530 biolink:NamedThing abnormal GTPase activity A molecular function phenotype in which the observed rate of GTPase activity is abnormal. FYPO_relaxed.owl FYPO:0001750 biolink:NamedThing abnormal homocitrate synthase activity A molecular function phenotype in which the observed rate of homocitrate synthase activity is abnormal. FYPO_relaxed.owl FYPO:0001771 biolink:NamedThing abnormal tRNA methyltransferase activity A molecular function phenotype in which the observed rate of a tRNA methyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0001816 biolink:NamedThing abnormal phosphoribosylamine-glycine ligase activity A molecular function phenotype in which the observed rate of phosphoribosylamine-glycine ligase activity is abnormal. FYPO_relaxed.owl FYPO:0001818 biolink:NamedThing abnormal phosphoribosylformylglycinamidine cyclo-ligase activity A molecular function phenotype in which the observed rate of phosphoribosylformylglycinamidine cyclo-ligase activity is abnormal. FYPO_relaxed.owl FYPO:0001831 biolink:NamedThing abnormal phosphoglycerate mutase activity A molecular function phenotype in which the observed rate of phosphoglycerate mutase activity is abnormal. FYPO_relaxed.owl FYPO:0001841 biolink:NamedThing abnormal adenylyl cyclase activity A molecular function phenotype in which the observed rate of adenylyl cyclase activity is abnormal. FYPO_relaxed.owl FYPO:0001912 biolink:NamedThing abnormal ubiquitin ligase activity A molecular function phenotype in which the observed rate of ubiquitin ligase activity is abnormal. FYPO_relaxed.owl FYPO:0001960 biolink:NamedThing abnormal DNA topoisomerase II activity A molecular function phenotype in which the observed rate of DNA topoisomerase II activity is abnormal. FYPO_relaxed.owl FYPO:0001997 biolink:NamedThing abnormal nucleoside diphosphate kinase activity A molecular function phenotype in which the observed rate of nucleoside diphosphate kinase activity is abnormal. FYPO_relaxed.owl FYPO:0002034 biolink:NamedThing abnormal DNA topoisomerase type I activity A molecular function phenotype in which the observed rate of DNA topoisomerase type I activity is abnormal. FYPO_relaxed.owl FYPO:0002267 biolink:NamedThing abnormal glutamate-ammonia ligase activity A molecular function phenotype in which the observed rate of glutamate-ammonia ligase activity is abnormal. FYPO_relaxed.owl FYPO:0002808 biolink:NamedThing abnormal 6,7-dimethyl-8-ribityllumazine synthase activity A molecular function phenotype in which the observed rate of 6,7-dimethyl-8-ribityllumazine synthase activity is abnormal. FYPO_relaxed.owl FYPO:0002853 biolink:NamedThing abnormal glutamate-cysteine ligase activity A molecular function phenotype in which the observed rate of glutamate-cysteine ligase activity is abnormal. FYPO_relaxed.owl FYPO:0002860 biolink:NamedThing abnormal poly(U) polymerase activity A molecular function phenotype in which the observed rate of polynucleotide uridylyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0003147 biolink:NamedThing abnormal UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity A molecular function phenotype in which the observed rate of UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity is abnormal. FYPO_relaxed.owl FYPO:0003163 biolink:NamedThing abnormal nuclease activity A molecular function phenotype in which the observed rate of a nuclease activity is abnormal. All nuclease activities may be abnormal, or a specific nuclease activity may be assayed. FYPO_relaxed.owl FYPO:0003167 biolink:NamedThing abnormal protein farnesyltransferase activity A molecular function phenotype in which the observed rate of protein farnesyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0003309 biolink:NamedThing abnormal IMP cyclohydrolase activity A molecular function phenotype in which the observed rate of IMP cyclohydrolase activity is abnormal. FYPO_relaxed.owl FYPO:0003311 biolink:NamedThing abnormal phosphoribosylaminoimidazolecarboxamide formyltransferase activity A molecular function phenotype in which the observed rate of phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR formyltransferase) activity is abnormal. FYPO_relaxed.owl FYPO:0003347 biolink:NamedThing altered substrate specificity A molecular function phenotype in which the substrate specificity of a catalytic activity differs from wild type. FYPO_relaxed.owl FYPO:0003495 biolink:NamedThing abnormal azetidine-2-carboxylic acid acetyltransferase activity A molecular function phenotype in which the observed rate of azetidine-2-carboxylic acid acetyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0003608 biolink:NamedThing abnormal dehydrodolichyl diphosphate synthase activity A molecular function phenotype in which the observed rate of dehydrodolichyl diphosphate synthase activity is abnormal. FYPO_relaxed.owl FYPO:0003642 biolink:NamedThing abnormal urease activity A molecular function phenotype in which the observed rate of urease activity is abnormal. FYPO_relaxed.owl FYPO:0003663 biolink:NamedThing abnormal RNA pyrophosphohydrolase activity A molecular function phenotype in which the observed rate of RNA pyrophosphohydrolase activity is abnormal. FYPO_relaxed.owl FYPO:0003703 biolink:NamedThing abnormal histone deacetylase activity A molecular function phenotype in which the observed rate of histone deacetylase activity is abnormal. FYPO_relaxed.owl FYPO:0003723 biolink:NamedThing abnormal bis(5'-adenosyl)-hexaphosphatase activity A molecular function phenotype in which the observed rate of bis(5'-adenosyl)-hexaphosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0003899 biolink:NamedThing abnormal triphosphatase activity A molecular function phenotype in which the observed rate of a triphosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0003939 biolink:NamedThing abnormal m7G(5')pppN diphosphatase activity A molecular function phenotype in which the observed rate of m7G(5')pppN diphosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0003958 biolink:NamedThing abnormal diacylglycerol O-acyltransferase activity A molecular function phenotype in which the observed rate of diacylglycerol O-acyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0003961 biolink:NamedThing abnormal phospholipid:diacylglycerol acyltransferase activity A molecular function phenotype in which the observed rate of phospholipid:diacylglycerol acyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0003980 biolink:NamedThing abnormal glutathione transferase activity A molecular function phenotype in which the observed rate of glutathione transferase activity is abnormal. FYPO_relaxed.owl FYPO:0004302 biolink:NamedThing abnormal phosphatase activity A molecular function phenotype in which the observed rate of a phosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0004563 biolink:NamedThing abnormal alpha-galactosidase activity A molecular function phenotype in which the observed rate of alpha-galactosidase activity is abnormal. FYPO_relaxed.owl FYPO:0004640 biolink:NamedThing abnormal CAAX-protein geranylgeranyltransferase activity A molecular function phenotype in which the observed rate of CAAX-protein geranylgeranyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0004644 biolink:NamedThing abnormal bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity A molecular function phenotype in which the observed rate of bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity is abnormal. FYPO_relaxed.owl FYPO:0004777 biolink:NamedThing abnormal farnesyltranstransferase activity A molecular function phenotype in which the observed rate of farnesyltranstransferase activity is abnormal. FYPO_relaxed.owl FYPO:0004856 biolink:NamedThing abnormal endo-1,6-beta-glucosidase activity A molecular function phenotype in which the observed rate of glucan endo-1,6-beta-glucosidase activity is abnormal. FYPO_relaxed.owl FYPO:0004898 biolink:NamedThing abnormal pyruvate decarboxylase activity A molecular function phenotype in which the observed rate of pyruvate decarboxylase activity is abnormal. FYPO_relaxed.owl FYPO:0005098 biolink:NamedThing abnormal poly(A) polymerase activity A molecular function phenotype in which the observed rate of poly(A) polymerase activity (EC name polynucleotide adenylyltransferase activity) is abnormal. FYPO_relaxed.owl FYPO:0005519 biolink:NamedThing abnormal nucleosome-dependent ATPase activity A molecular function phenotype in which the observed rate of nucleosome-dependent ATPase activity is abnormal. FYPO_relaxed.owl FYPO:0005723 biolink:NamedThing abnormal protein methyltransferase activity A molecular function phenotype in which the observed rate of protein methyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0005730 biolink:NamedThing abnormal arginase activity A molecular function phenotype in which the observed rate of arginase activity is abnormal. FYPO_relaxed.owl FYPO:0005741 biolink:NamedThing abnormal invertase activity A molecular function phenotype in which the observed rate of invertase activity (beta-fructofuranosidase activity) is abnormal. FYPO_relaxed.owl FYPO:0006310 biolink:NamedThing abnormal DNA-3'-diphospho-5'-guanosine diphosphatase activity A molecular function phenotype in which the observed rate of DNA-3'-diphospho-5'-guanosine diphosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0006453 biolink:NamedThing abnormal histone acetyltransferase activity A molecular function phenotype in which the observed rate or other catalytic property of a histone acetyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0006491 biolink:NamedThing abnormal chitin synthase activity A molecular function phenotype in which the observed rate of chitin synthase activity is abnormal. FYPO_relaxed.owl FYPO:0006647 biolink:NamedThing abnormal 5'-3' DNA/RNA helicase activity A molecular function phenotype in which the observed rate of 5'-3' DNA/RNA helicase activity is abnormal. FYPO_relaxed.owl FYPO:0006650 biolink:NamedThing abnormal ATP-dependent protein-DNA complex displacement activity A molecular function phenotype in which the observed rate of an ATP-dependent protein-DNA complex displacement activity is abnormal. FYPO_relaxed.owl FYPO:0006805 biolink:NamedThing abnormal galactosyltransferase activity A molecular function phenotype in which the observed rate of a galactosyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0006891 biolink:NamedThing abnormal inositol hexakisphosphate kinase activity A molecular function phenotype in which the observed rate of inositol hexakisphosphate kinase activity is abnormal. FYPO_relaxed.owl FYPO:0007129 biolink:NamedThing abnormal homoserine O-acetyltransferase activity A molecular function phenotype in which the observed rate of homoserine O-acetyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0007228 biolink:NamedThing abnormal 3'-deoxyribose phosphate lyase activity A molecular function phenotype in which the observed rate of 3'-deoxyribose phosphate lyase activity is abnormal. FYPO_relaxed.owl FYPO:0007289 biolink:NamedThing abnormal UDP-glucose 4-epimerase activity A molecular function phenotype in which the observed rate of UDP-glucose 4-epimerase activity is abnormal. FYPO_relaxed.owl FYPO:0007503 biolink:NamedThing abnormal histone demethylase activity A molecular function phenotype in which the observed rate of a histone demethylase activity is abnormal. FYPO_relaxed.owl FYPO:0007762 biolink:NamedThing abnormal phosphatidate cytidylyltransferase activity A molecular function phenotype in which the observed rate of phosphatidate cytidylyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0007804 biolink:NamedThing abnormal H3-H4 dimer loading onto DNA A molecular function phenotype in which the ATP hydrolysis-dependent activity that loads H3-H4 histone dimers onto DNA is abnormal. FYPO_relaxed.owl FYPO:0007839 biolink:NamedThing abnormal peptide alpha-N-acetyltransferase activity A molecular function phenotype in which the observed rate of peptide alpha-N-acetyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0008057 biolink:NamedThing abnormal enzyme processivity A molecular function phenotype in which the observed ability of an enzyme to catalyze consecutive reactions without releasing the substrate (i.e. template) is abnormal. FYPO_relaxed.owl FYPO:0008216 biolink:NamedThing abnormal DNA N-glycosylase activity A molecular function phenotype in which the observed rate of DNA N-glycosylase activity is abnormal. FYPO_relaxed.owl FYPO:0008289 biolink:NamedThing abnormal guanyl-nucleotide exchange factor activity A molecular function phenotype in which a guanyl-nucleotide exchange factor activity is abnormal. FYPO_relaxed.owl FYPO:0000665 biolink:NamedThing normal peptidase activity A molecular function phenotype in which the observed rate of a peptidase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000686 biolink:NamedThing normal peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity A molecular function phenotype in which the observed rate of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000691 biolink:NamedThing normal DNA-1,N6-ethenoadenine N-glycosylase activity A molecular function phenotype in which the observed rate of DNA-1,N6-ethenoadenine N-glycosylase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000696 biolink:NamedThing normal DNA-7-methylguanine glycosylase activity A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000719 biolink:NamedThing normal fatty acid synthase activity A molecular function phenotype in which the observed rate of fatty acid synthase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000753 biolink:NamedThing normal glutathione gamma-glutamylcysteinyltransferase activity A molecular function phenotype in which the observed rate of glutathione gamma-glutamylcysteinyltransferase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000792 biolink:NamedThing normal glycerol dehydrogenase activity A molecular function phenotype in which the observed rate of glycerol dehydrogenase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000914 biolink:NamedThing normal glutamate-ammonia ligase activity A molecular function phenotype in which the observed rate of glutamate-ammonia ligase (also known as glutamine synthetase) activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000981 biolink:NamedThing normal glutamate dehydrogenase (NAD+) activity A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAD+ as a cofactor is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001086 biolink:NamedThing normal glucosyltransferase activity A molecular function phenotype in which the observed rate of a glucosyltransferase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001182 biolink:NamedThing normal alpha-glucosidase activity A molecular function phenotype in which the observed rate of an alpha-glucosidase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001295 biolink:NamedThing normal palmitoyl-CoA ligase activity A molecular function phenotype in which the observed rate of palmitoyl-CoA ligase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001296 biolink:NamedThing normal oleoyl-CoA ligase activity A molecular function phenotype in which the observed rate of oleoyl-CoA ligase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001480 biolink:NamedThing normal alpha,alpha-trehalase activity A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001672 biolink:NamedThing normal GTPase activity A molecular function phenotype in which the observed rate of a GTPase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001770 biolink:NamedThing normal tRNA methyltransferase activity A molecular function phenotype in which the observed rate of a tRNA methyltransferase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001834 biolink:NamedThing normal phosphoglycerate mutase activity A molecular function phenotype in which the observed rate of phosphoglycerate mutase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001866 biolink:NamedThing normal adenylyl cyclase activity A molecular function phenotype in which the observed rate of adenylyl cyclase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002053 biolink:NamedThing normal DNA topoisomerase II activity A molecular function phenotype in which the observed rate of DNA topoisomerase II activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002065 biolink:NamedThing normal 3'-5'-exoribonuclease activity A molecular function phenotype in which the observed rate of a 3'-5'-exoribonuclease activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003075 biolink:NamedThing normal protein kinase activity A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003361 biolink:NamedThing normal superoxide dismutase activity A molecular function phenotype in which the observed rate of superoxide dismutase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003665 biolink:NamedThing normal RNA pyrophosphohydrolase activity A molecular function phenotype in which the observed rate of RNA pyrophosphohydrolase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003901 biolink:NamedThing normal triphosphatase activity A molecular function phenotype in which the observed rate of a triphosphatase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003942 biolink:NamedThing normal m7G(5')pppN diphosphatase activity A molecular function phenotype in which the observed rate of m7G(5')pppN diphosphatase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003994 biolink:NamedThing normal succinate dehydrogenase activity A molecular function phenotype in which the observed rate of succinate dehydrogenase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004017 biolink:NamedThing normal cytochrome-c oxidase activity A molecular function phenotype in which the observed rate of cytochrome-c oxidase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004027 biolink:NamedThing normal 5' deoxyribonuclease (pyrimidine dimer) activity A molecular function phenotype in which the observed rate of 5' deoxyribonuclease (pyrimidine dimer) activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004041 biolink:NamedThing normal primary amine oxidase activity A molecular function phenotype in which the observed rate of a primary amine oxidase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004123 biolink:NamedThing normal glutathione disulfide oxidoreductase activity A molecular function phenotype in which the observed rate of a glutathione disulfide oxidoreductase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004132 biolink:NamedThing normal sulfite reductase activity A molecular function phenotype in which the observed rate of sulfite reductase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004148 biolink:NamedThing normal pyridoxamine-phosphate oxidase activity A molecular function phenotype in which the observed rate of pyridoxamine-phosphate oxidase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004149 biolink:NamedThing normal pyridoxal kinase activity A molecular function phenotype in which the observed rate of pyridoxal kinase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004300 biolink:NamedThing normal ATPase activity A molecular function phenotype in which the observed rate of an ATPase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004469 biolink:NamedThing normal phosphatase activity A molecular function phenotype in which the observed rate of a phosphatase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004637 biolink:NamedThing normal DNA-directed DNA polymerase activity A molecular function phenotype in which the observed rate and other catalytic properties of a DNA-directed DNA polymerase activity are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004642 biolink:NamedThing normal protein farnesyltransferase activity A molecular function phenotype in which the observed rate of a protein farnesyltransferase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004643 biolink:NamedThing normal Rab geranylgeranyltransferase activity A molecular function phenotype in which the observed rate of Rab geranylgeranyltransferase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004779 biolink:NamedThing normal farnesyltranstransferase activity A molecular function phenotype in which the observed rate of farnesyltranstransferase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004787 biolink:NamedThing normal DNA/DNA annealing activity A molecular function phenotype in which the observed rate of a DNA/DNA annealing activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005100 biolink:NamedThing normal poly(U) polymerase activity A molecular function phenotype in which the observed rate of poly(U) polymerase activity (EC name RNA uridylyltransferase activity) is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005297 biolink:NamedThing normal 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity A molecular function phenotype in which the observed rate of 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005473 biolink:NamedThing normal glutamate synthase (NADH) activity A molecular function phenotype in which the observed rate of glutamate synthase activity using NADH as a cofactor is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005474 biolink:NamedThing normal glutamate dehydrogenase (NADP+) activity A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAPD+ as a cofactor is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005481 biolink:NamedThing normal diphosphoinositol-pentakisphosphate kinase activity A molecular function phenotype in which the observed rate of an diphosphoinositol-pentakisphosphate kinase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005743 biolink:NamedThing normal invertase activity during glucose starvation A molecular function phenotype in which the observed rate of invertase activity (beta-fructofuranosidase activity) is normal (i.e. indistinguishable from wild type) under conditions of glucose starvation. FYPO_relaxed.owl FYPO:0006804 biolink:NamedThing normal 5'-deoxyribose-5-phosphate lyase activity A molecular function phenotype in which the observed rate and other catalytic properties of a 5'-deoxyribose-5-phosphate lyase activity are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006835 biolink:NamedThing normal glucan endo-1,3-beta-glucanase activity A molecular function phenotype in which the observed rate of glucan endo-1,3-beta-glucanase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006943 biolink:NamedThing normal 3'-5' RNA helicase activity A molecular function phenotype in which the observed rate of an 3'-5' RNA helicase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007490 biolink:NamedThing normal mannosyltransferase activity A molecular function phenotype in which the observed rate of a mannosyltransferase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007838 biolink:NamedThing normal peptide alpha-N-acetyltransferase activity A molecular function phenotype in which the observed rate of peptide alpha-N-acetyltransferase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008013 biolink:NamedThing normal inositol hexakisphosphate kinase activity A molecular function phenotype in which the observed rate of inositol hexakisphosphate kinase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008079 biolink:NamedThing normal inositol heptakisphosphate 5-kinase activity A molecular function phenotype in which the observed rate and other catalytic properties of a inositol heptakisphosphate 5-kinase are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008275 biolink:NamedThing normal polyphosphatase activity A molecular function phenotype in which the observed rate of a polyphosphatase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000668 biolink:NamedThing decreased peptidase activity A molecular function phenotype in which the observed rate of a peptidase activity is decreased. FYPO_relaxed.owl FYPO:0000669 biolink:NamedThing abolished peptidase activity A molecular function phenotype in which a peptidase activity is absent. FYPO_relaxed.owl FYPO:0003111 biolink:NamedThing abnormal ubiquitinyl hydrolase activity A molecular function phenotype in which the observed rate of ubiquitinyl hydrolase activity is abnormal. FYPO_relaxed.owl FYPO:0004128 biolink:NamedThing abnormal cysteine-type peptidase activity A molecular function phenotype in which the observed rate of a cysteine-type peptidase activity is abnormal. FYPO_relaxed.owl FYPO:0005255 biolink:NamedThing abnormal carboxypeptidase activity A molecular function phenotype in which the observed rate of a carboxypeptidase activity is abnormal. FYPO_relaxed.owl FYPO:0005821 biolink:NamedThing abnormal NEDD8-specific protease activity A molecular function phenotype in which the observed rate of NEDD8-specific protease activity (deneddylase activity) is abnormal. FYPO_relaxed.owl FYPO:0006089 biolink:NamedThing abnormal glutathione hydrolase activity A molecular function phenotype in which the observed rate of glutathione hydrolase activity is abnormal. FYPO_relaxed.owl FYPO:0006151 biolink:NamedThing abnormal SUMO-specific protease activity A molecular function phenotype in which the observed rate of SUMO-specific protease activity is abnormal. FYPO_relaxed.owl FYPO:0000690 biolink:NamedThing decreased oxidoreductase activity A molecular function phenotype in which the observed rate of an oxidoreductase activity is decreased. FYPO_relaxed.owl FYPO:0000693 biolink:NamedThing decreased DNA-1,N6-ethenoadenine N-glycosylase activity A molecular function phenotype in which the observed rate of DNA-1,N6-ethenoadenine N-glycosylase activity is decreased. FYPO_relaxed.owl FYPO:0000698 biolink:NamedThing decreased DNA-7-methylguanine glycosylase activity A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is decreased. FYPO_relaxed.owl FYPO:0000755 biolink:NamedThing decreased glutathione gamma-glutamylcysteinyltransferase activity A molecular function phenotype in which the observed rate of glutathione gamma-glutamylcysteinyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0000848 biolink:NamedThing abnormal chromosome morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of one or more chromosomes is abnormal. FYPO_relaxed.owl FYPO:0000918 biolink:NamedThing decreased citrate (Si)-synthase activity A molecular function phenotype in which the observed rate of citrate (Si)-synthase activity is decreased. FYPO_relaxed.owl FYPO:0001040 biolink:NamedThing decreased thiamine diphosphokinase activity A molecular function phenotype in which the observed rate of thiamine diphosphokinase activity is decreased. FYPO_relaxed.owl FYPO:0001088 biolink:NamedThing decreased glucosyltransferase activity A molecular function phenotype in which the observed rate of a glucosyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0001168 biolink:NamedThing decreased ATPase activity A molecular function phenotype in which the observed rate of ATPase activity is decreased. FYPO_relaxed.owl FYPO:0001292 biolink:NamedThing decreased CDP-diacylglycerol-serine O-phosphatidyltransferase activity A molecular function phenotype in which the observed rate of CDP-diacylglycerol-serine O-phosphatidyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0001307 biolink:NamedThing decreased long-chain fatty acid-CoA ligase activity A molecular function phenotype in which the observed rate of long-chain fatty acid-CoA ligase activity is decreased. FYPO_relaxed.owl FYPO:0001382 biolink:NamedThing decreased protein kinase activity A molecular function phenotype in which the observed rate of a protein kinase activity is decreased. FYPO_relaxed.owl FYPO:0001477 biolink:NamedThing decreased guanosine-diphosphatase activity A molecular function phenotype in which the observed rate of guanosine-diphosphatase activity is decreased. FYPO_relaxed.owl FYPO:0001503 biolink:NamedThing decreased alpha,alpha-trehalase activity during sporulation A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is lower than normal during sporulation. FYPO_relaxed.owl FYPO:0001531 biolink:NamedThing decreased GTPase activity A molecular function phenotype in which the observed rate of GTPase activity is decreased. FYPO_relaxed.owl FYPO:0001752 biolink:NamedThing decreased homocitrate synthase activity A molecular function phenotype in which the observed rate of homocitrate synthase activity is decreased. FYPO_relaxed.owl FYPO:0001772 biolink:NamedThing decreased tRNA methyltransferase activity A molecular function phenotype in which the observed rate of a tRNA methyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0001868 biolink:NamedThing decreased adenylyl cyclase activity A molecular function phenotype in which the observed rate of adenylyl cyclase activity is decreased. FYPO_relaxed.owl FYPO:0001936 biolink:NamedThing decreased proton-transporting ATP synthase activity, rotational mechanism A molecular function phenotype in which the observed rate of proton-transporting ATP synthase activity by a rotational mechanism is decreased. FYPO_relaxed.owl FYPO:0001961 biolink:NamedThing decreased DNA topoisomerase II activity A molecular function phenotype in which the observed rate of DNA topoisomerase II activity is decreased. FYPO_relaxed.owl FYPO:0001998 biolink:NamedThing decreased nucleoside diphosphate kinase activity A molecular function phenotype in which the observed rate of nucleoside diphosphate kinase activity is decreased. FYPO_relaxed.owl FYPO:0002008 biolink:NamedThing decreased aconitate hydratase activity A molecular function phenotype in which the observed rate of aconitate hydratase (also known as aconitase) activity is decreased. FYPO_relaxed.owl FYPO:0002035 biolink:NamedThing decreased DNA topoisomerase type I activity A molecular function phenotype in which the observed rate of DNA topoisomerase type I activity is decreased. FYPO_relaxed.owl FYPO:0002269 biolink:NamedThing decreased glutamate-ammonia ligase activity A molecular function phenotype in which the observed rate of glutamate-ammonia ligase activity is decreased. FYPO_relaxed.owl FYPO:0002755 biolink:NamedThing decreased cysteine synthase activity A molecular function phenotype in which the observed rate of cysteine synthase activity is decreased. FYPO_relaxed.owl FYPO:0002809 biolink:NamedThing decreased 6,7-dimethyl-8-ribityllumazine synthase activity A molecular function phenotype in which the observed rate of 6,7-dimethyl-8-ribityllumazine synthase activity is decreased. FYPO_relaxed.owl FYPO:0002855 biolink:NamedThing decreased glutamate-cysteine ligase activity A molecular function phenotype in which the observed rate of glutamate-cysteine ligase activity is decreased. FYPO_relaxed.owl FYPO:0002861 biolink:NamedThing decreased poly(U) polymerase activity A molecular function phenotype in which the observed rate of polynucleotide uridylyltransferase (poly(U) polymerase) activity is decreased. FYPO_relaxed.owl FYPO:0003405 biolink:NamedThing decreased glyoxalase III activity A molecular function phenotype in which the observed rate of glyoxalase III activity is decreased. FYPO_relaxed.owl FYPO:0003434 biolink:NamedThing decreased ornithine carbamoyltransferase activity A molecular function phenotype in which the observed rate of ornithine carbamoyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0003464 biolink:NamedThing decreased alpha,alpha-trehalase activity during cellular response to heat A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is lower than normal during a cellular response to heat. FYPO_relaxed.owl FYPO:0003465 biolink:NamedThing decreased alpha,alpha-trehalase activity during cellular response to salt stress A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is lower than normal during a cellular response to salt stress. FYPO_relaxed.owl FYPO:0003609 biolink:NamedThing decreased dehydrodolichyl diphosphate synthase activity A molecular function phenotype in which the observed rate of dehydrodolichyl diphosphate synthase activity is decreased. FYPO_relaxed.owl FYPO:0003643 biolink:NamedThing decreased urease activity A molecular function phenotype in which the observed rate of urease activity is decreased. FYPO_relaxed.owl FYPO:0003704 biolink:NamedThing decreased histone deacetylase activity A molecular function phenotype in which the observed rate of histone deacetylase activity is decreased. FYPO_relaxed.owl FYPO:0003724 biolink:NamedThing decreased bis(5'-adenosyl)-hexaphosphatase activity A molecular function phenotype in which the observed rate of bis(5'-adenosyl)-hexaphosphatase activity is decreased. FYPO_relaxed.owl FYPO:0003819 biolink:NamedThing decreased 5'-3' DNA helicase activity A molecular function phenotype in which the observed rate of 5'-3' DNA helicase activity is decreased. FYPO_relaxed.owl FYPO:0003900 biolink:NamedThing decreased triphosphatase activity A molecular function phenotype in which the observed rate of a triphosphatase activity is decreased. FYPO_relaxed.owl FYPO:0003941 biolink:NamedThing decreased m7G(5')pppN diphosphatase activity A molecular function phenotype in which the observed rate of m7G(5')pppN diphosphatase activity is decreased. FYPO_relaxed.owl FYPO:0003959 biolink:NamedThing decreased diacylglycerol O-acyltransferase activity A molecular function phenotype in which the observed rate of diacylglycerol O-acyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0003962 biolink:NamedThing decreased phospholipid:diacylglycerol acyltransferase activity A molecular function phenotype in which the observed rate of phospholipid:diacylglycerol acyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0003997 biolink:NamedThing decreased DNA primase activity A molecular function phenotype in which the observed rate of DNA primase activity is decreased. FYPO_relaxed.owl FYPO:0004034 biolink:NamedThing decreased glutathione transferase activity A molecular function phenotype in which the observed rate of glutathione transferase activity is decreased. FYPO_relaxed.owl FYPO:0004253 biolink:NamedThing decreased nuclease activity A molecular function phenotype in which the observed rate of a nuclease activity is decreased. FYPO_relaxed.owl FYPO:0004278 biolink:NamedThing decreased uracil DNA N-glycosylase activity A molecular function phenotype in which the observed rate of uracil DNA N-glycosylase activity is decreased. FYPO_relaxed.owl FYPO:0004280 biolink:NamedThing decreased hypoxanthine DNA N-glycosylase activity A molecular function phenotype in which the observed rate of hypoxanthine DNA N-glycosylase activity is decreased. FYPO_relaxed.owl FYPO:0004282 biolink:NamedThing decreased xanthine DNA N-glycosylase activity A molecular function phenotype in which the observed rate of xanthine DNA N-glycosylase activity is decreased. FYPO_relaxed.owl FYPO:0004284 biolink:NamedThing decreased oxanine DNA N-glycosylase activity A molecular function phenotype in which the observed rate of oxanine DNA N-glycosylase activity is decreased. FYPO_relaxed.owl FYPO:0004304 biolink:NamedThing decreased phosphatase activity A molecular function phenotype in which the observed rate of a phosphatase activity is decreased. FYPO_relaxed.owl FYPO:0004641 biolink:NamedThing decreased CAAX-protein geranylgeranyltransferase activity A molecular function phenotype in which the observed rate of CAAX-protein geranylgeranyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0004778 biolink:NamedThing decreased farnesyltranstransferase activity A molecular function phenotype in which the observed rate of farnesyltranstransferase activity is decreased. FYPO_relaxed.owl FYPO:0004899 biolink:NamedThing decreased pyruvate decarboxylase activity during stationary phase A molecular function phenotype in which the observed rate of pyruvate decarboxylase activity is decreased when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0005099 biolink:NamedThing decreased poly(A) polymerase activity A molecular function phenotype in which the observed rate of poly(A) polymerase activity (EC name polynucleotide adenylyltransferase activity) is decreased. FYPO_relaxed.owl FYPO:0005439 biolink:NamedThing decreased DNA/DNA annealing activity A molecular function phenotype in which the observed rate of DNA/DNA annealing activity is decreased. FYPO_relaxed.owl FYPO:0005540 biolink:NamedThing decreased telomerase RNA reverse transcriptase activity A molecular function phenotype in which the observed rate of telomerase RNA reverse transcriptase activity is decreased. FYPO_relaxed.owl FYPO:0005725 biolink:NamedThing decreased protein methyltransferase activity A molecular function phenotype in which the observed rate of protein methyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0005731 biolink:NamedThing decreased arginase activity A molecular function phenotype in which the observed rate of arginase activity is decreased. FYPO_relaxed.owl FYPO:0005742 biolink:NamedThing decreased invertase activity during glucose starvation A molecular function phenotype in which the observed rate of invertase activity (beta-fructofuranosidase activity) is decreased under conditions of glucose starvation. FYPO_relaxed.owl FYPO:0006312 biolink:NamedThing decreased DNA-3'-diphospho-5'-guanosine diphosphatase activity A molecular function phenotype in which the observed rate of DNA-3'-diphospho-5'-guanosine diphosphatase activity is decreased. FYPO_relaxed.owl FYPO:0006582 biolink:NamedThing decreased bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity A molecular function phenotype in which the observed rate of bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity is decreased. FYPO_relaxed.owl FYPO:0006648 biolink:NamedThing decreased 5'-3' DNA/RNA helicase activity A molecular function phenotype in which the observed rate of 5'-3' DNA/RNA helicase activity is decreased. FYPO_relaxed.owl FYPO:0006806 biolink:NamedThing decreased galactosyltransferase activity A molecular function phenotype in which the observed rate of a galactosyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0006893 biolink:NamedThing decreased inositol hexakisphosphate kinase activity A molecular function phenotype in which the observed rate of inositol hexakisphosphate kinase activity is decreased. FYPO_relaxed.owl FYPO:0007290 biolink:NamedThing decreased UDP-glucose 4-epimerase activity A molecular function phenotype in which the observed rate of UDP-glucose 4-epimerase activity is decreased. FYPO_relaxed.owl FYPO:0007763 biolink:NamedThing decreased phosphatidate cytidylyltransferase activity A molecular function phenotype in which the observed rate of phosphatidate cytidylyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0007797 biolink:NamedThing decreased glucan 1,3-alpha-glucosidase activity A molecular function phenotype in which the observed rate of glucan 1,3-alpha-glucosidase activity is decreased. FYPO_relaxed.owl FYPO:0007841 biolink:NamedThing decreased peptide alpha-N-acetyltransferase activity A molecular function phenotype in which the observed rate of peptide alpha-N-acetyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0008010 biolink:NamedThing decreased RNA-dependent RNA polymerase A molecular function phenotype in which the observed rate of RNA-dependent RNA polymerase activity is decreased. FYPO_relaxed.owl FYPO:0008039 biolink:NamedThing decreased 1-phosphatidylinositol-4-phosphate 5-kinase activity A molecular function phenotype in which the observed rate of a decreased 1-phosphatidylinositol-4-phosphate 5-kinase activity is decreased. FYPO_relaxed.owl FYPO:0008055 biolink:NamedThing decreased Glc2Man9GlcNAc2 oligosaccharide glucosidase activity A molecular function phenotype in which the observed rate of a Glc2Man9GlcNAc2 oligosaccharide glucosidase activity is decreased. FYPO_relaxed.owl FYPO:0008080 biolink:NamedThing decreased inositol heptakisphosphate 5-kinase activity A molecular function phenotype in which the observed rate of a heptakisphosphate 5-kinase is decreased. FYPO_relaxed.owl FYPO:0008116 biolink:NamedThing decreased phosphoglycerate mutase activity A molecular function phenotype in which the observed rate of a phosphoglycerate mutase activity is decreased. FYPO_relaxed.owl FYPO:0000694 biolink:NamedThing abolished DNA-1,N6-ethenoadenine N-glycosylase activity A molecular function phenotype in which DNA-1,N6-ethenoadenine N-glycosylase activity is absent. FYPO_relaxed.owl FYPO:0000699 biolink:NamedThing abolished DNA-7-methylguanine glycosylase activity A molecular function phenotype in which DNA-7-methylguanine glycosylase activity is absent. FYPO_relaxed.owl FYPO:0000794 biolink:NamedThing abolished glycerol dehydrogenase activity A molecular function phenotype in which glycerol dehydrogenase activity is absent. FYPO_relaxed.owl FYPO:0001105 biolink:NamedThing abolished catalase activity A molecular function phenotype in which catalase activity is absent. FYPO_relaxed.owl FYPO:0001205 biolink:NamedThing abolished alpha-glucosidase activity A molecular function phenotype in which alpha-glucosidase activity is absent. FYPO_relaxed.owl FYPO:0001306 biolink:NamedThing abolished long-chain fatty acid-CoA ligase activity A molecular function phenotype in which long-chain fatty acid-CoA ligase activity is absent. FYPO_relaxed.owl FYPO:0001384 biolink:NamedThing abolished protein kinase activity A molecular function phenotype in which a protein kinase activity is absent. FYPO_relaxed.owl FYPO:0001773 biolink:NamedThing abolished tRNA methyltransferase activity A molecular function phenotype in which a tRNA methyltransferase activity is absent. FYPO_relaxed.owl FYPO:0001817 biolink:NamedThing abolished phosphoribosylamine-glycine ligase activity A molecular function phenotype in which phosphoribosylamine-glycine ligase activity is absent. FYPO_relaxed.owl FYPO:0001819 biolink:NamedThing abolished phosphoribosylformylglycinamidine cyclo-ligase activity A molecular function phenotype in which phosphoribosylformylglycinamidine cyclo-ligase activity is absent. FYPO_relaxed.owl FYPO:0001832 biolink:NamedThing abolished phosphoglycerate mutase activity A molecular function phenotype in which phosphoglycerate mutase activity is absent. FYPO_relaxed.owl FYPO:0001848 biolink:NamedThing abolished ferric-chelate reductase activity A molecular function phenotype in which ferric-chelate reductase activity is absent. FYPO_relaxed.owl FYPO:0001869 biolink:NamedThing abolished adenylyl cyclase activity A molecular function phenotype in which adenylyl cyclase activity is absent. FYPO_relaxed.owl FYPO:0001913 biolink:NamedThing abolished ubiquitin ligase activity A molecular function phenotype in which ubiquitin ligase activity is absent. FYPO_relaxed.owl FYPO:0002101 biolink:NamedThing abolished 3'-5' DNA helicase activity A molecular function phenotype in which an 3'-5' DNA helicase activity is absent. FYPO_relaxed.owl FYPO:0002268 biolink:NamedThing abolished glutamate-ammonia ligase activity A molecular function phenotype in which glutamate-ammonia ligase activity is absent. FYPO_relaxed.owl FYPO:0002696 biolink:NamedThing abolished methylenetetrahydrofolate reductase (NADPH) activity A molecular function phenotype in which methylenetetrahydrofolate reductase (NADPH) activity is absent. FYPO_relaxed.owl FYPO:0002854 biolink:NamedThing abolished glutamate-cysteine ligase activity A molecular function phenotype in which glutamate-cysteine ligase activity is absent. FYPO_relaxed.owl FYPO:0002857 biolink:NamedThing abolished glutathione synthase activity A molecular function phenotype in which glutathione synthase activity is absent. FYPO_relaxed.owl FYPO:0003164 biolink:NamedThing abolished nuclease activity A molecular function phenotype in which nuclease activity is absent. All nuclease activities may be absent, or a specific nuclease activity may be assayed. FYPO_relaxed.owl FYPO:0003168 biolink:NamedThing abolished protein farnesyltransferase activity A molecular function phenotype in which protein farnesyltransferase activity is absent. FYPO_relaxed.owl FYPO:0003310 biolink:NamedThing abolished IMP cyclohydrolase activity A molecular function phenotype in which IMP cyclohydrolase activity is absent. FYPO_relaxed.owl FYPO:0003312 biolink:NamedThing abolished phosphoribosylaminoimidazolecarboxamide formyltransferase activity A molecular function phenotype in which phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR formyltransferase) activity is absent. FYPO_relaxed.owl FYPO:0003323 biolink:NamedThing abolished succinate dehydrogenase (ubiquinone) activity A molecular function phenotype in which succinate dehydrogenase (ubiquinone) activity is absent. FYPO_relaxed.owl FYPO:0003360 biolink:NamedThing abolished superoxide dismutase activity A molecular function phenotype in which superoxide dismutase activity is absent. FYPO_relaxed.owl FYPO:0003404 biolink:NamedThing abolished glyoxalase III activity A molecular function phenotype in which glyoxalase III activity is absent. FYPO_relaxed.owl FYPO:0003418 biolink:NamedThing abolished malate dehydrogenase (decarboxylating) (NAD+) activity A molecular function phenotype in which malate dehydrogenase (decarboxylating) (NAD+) activity is absent. FYPO_relaxed.owl FYPO:0003463 biolink:NamedThing abolished alpha,alpha-trehalase activity A molecular function phenotype in which alpha,alpha-trehalase activity is absent. FYPO_relaxed.owl FYPO:0003496 biolink:NamedThing abolished azetidine-2-carboxylic acid acetyltransferase activity A molecular function phenotype in which azetidine-2-carboxylic acid acetyltransferase activity is absent. FYPO_relaxed.owl FYPO:0003505 biolink:NamedThing abolished glutathione gamma-glutamylcysteinyltransferase activity A molecular function phenotype in which glutathione gamma-glutamylcysteinyltransferase activity is absent. FYPO_relaxed.owl FYPO:0003654 biolink:NamedThing abolished cysteine synthase activity A molecular function phenotype in which cysteine synthase activity is absent. FYPO_relaxed.owl FYPO:0003664 biolink:NamedThing abolished RNA pyrophosphohydrolase activity A molecular function phenotype in which RNA pyrophosphohydrolase activity is absent. FYPO_relaxed.owl FYPO:0003674 biolink:NamedThing abolished ATPase activity A molecular function phenotype in which ATPase activity is absent. FYPO_relaxed.owl FYPO:0003741 biolink:NamedThing abolished cytochrome-c oxidase activity A molecular function phenotype in which cytochrome-c oxidase activity is absent. FYPO_relaxed.owl FYPO:0003818 biolink:NamedThing abolished 5'-3' DNA helicase activity A molecular function phenotype in which 5'-3' DNA helicase activity is absent. FYPO_relaxed.owl FYPO:0003940 biolink:NamedThing abolished m7G(5')pppN diphosphatase activity A molecular function phenotype in which m7G(5')pppN diphosphatase activity is absent. FYPO_relaxed.owl FYPO:0003996 biolink:NamedThing abolished DNA primase activity A molecular function phenotype in which DNA primase activity is absent. FYPO_relaxed.owl FYPO:0004039 biolink:NamedThing abolished primary amine oxidase activity A molecular function phenotype in which primary amine oxidase activity is absent. FYPO_relaxed.owl FYPO:0004209 biolink:NamedThing abolished histone methyltransferase activity (H3-K4 specific) A molecular function phenotype in which H3-K4 specific histone methyltransferase activity is absent. FYPO_relaxed.owl FYPO:0004303 biolink:NamedThing abolished phosphatase activity A molecular function phenotype in which a phosphatase activity is absent. FYPO_relaxed.owl FYPO:0004365 biolink:NamedThing abolished dioxygenase activity A molecular function phenotype in which a dioxygenase activity is absent. FYPO_relaxed.owl FYPO:0004677 biolink:NamedThing abolished purine-specific mismatch base pair DNA N-glycosylase activity A molecular function phenotype in which purine-specific mismatch base pair DNA N-glycosylase activity is absent. FYPO_relaxed.owl FYPO:0004908 biolink:NamedThing abolished L-aminoadipate-semialdehyde dehydrogenase activity A molecular function phenotype in which L-aminoadipate-semialdehyde dehydrogenase activity is absent. FYPO_relaxed.owl FYPO:0005471 biolink:NamedThing abolished glutamate synthase (NADH) activity A molecular function phenotype in which glutamate synthase activity using NADH as a cofactor is absent. FYPO_relaxed.owl FYPO:0005472 biolink:NamedThing abolished glutamate dehydrogenase (NADP+) activity A molecular function phenotype in which glutamate dehydrogenase activity using NAPD+ as a cofactor is absent. FYPO_relaxed.owl FYPO:0005520 biolink:NamedThing abolished nucleosome-dependent ATPase activity A molecular function phenotype in which nucleosome-dependent ATPase activity is absent. FYPO_relaxed.owl FYPO:0005732 biolink:NamedThing abolished arginase activity A molecular function phenotype in which arginase activity is absent. FYPO_relaxed.owl FYPO:0005762 biolink:NamedThing abolished homocitrate synthase activity A molecular function phenotype in which homocitrate synthase activity is absent. FYPO_relaxed.owl FYPO:0005848 biolink:NamedThing abolished histone methyltransferase activity (H3-K9 specific) activity A molecular function phenotype in which H3-K9 specific histone methyltransferase activity is absent. FYPO_relaxed.owl FYPO:0006311 biolink:NamedThing abolished DNA-3'-diphospho-5'-guanosine diphosphatase activity A molecular function phenotype in which DNA-3'-diphospho-5'-guanosine diphosphatase activity is absent. FYPO_relaxed.owl FYPO:0006492 biolink:NamedThing abolished chitin synthase activity A molecular function phenotype in which chitin synthase activity is absent. FYPO_relaxed.owl FYPO:0006649 biolink:NamedThing abolished 5'-3' DNA/RNA helicase activity A molecular function phenotype in which 5'-3' DNA/RNA helicase activity is absent. FYPO_relaxed.owl FYPO:0006651 biolink:NamedThing abolished ATP-dependent protein-DNA complex displacement activity A molecular function phenotype in which an ATP-dependent protein-DNA complex displacement activity is absent. FYPO_relaxed.owl FYPO:0006792 biolink:NamedThing abolished urease activity A molecular function phenotype in which urease activity is absent. FYPO_relaxed.owl FYPO:0006803 biolink:NamedThing abolished DNA-directed DNA polymerase activity A molecular function phenotype in which a DNA-directed DNA polymerase activity is absent. FYPO_relaxed.owl FYPO:0006892 biolink:NamedThing abolished inositol hexakisphosphate kinase activity A molecular function phenotype in which inositol hexakisphosphate kinase activity is absent. FYPO_relaxed.owl FYPO:0007130 biolink:NamedThing abolished homoserine O-acetyltransferase activity A molecular function phenotype in which homoserine O-acetyltransferase activity is absent. FYPO_relaxed.owl FYPO:0007229 biolink:NamedThing abolished 3'-deoxyribose phosphate lyase activity A molecular function phenotype in which 3'-deoxyribose phosphate lyase activity is absent. FYPO_relaxed.owl FYPO:0007504 biolink:NamedThing abolished histone demethylase activity (H3-K9 specific) A molecular function phenotype in which H3-K9 specific histone demethylase activity is absent. FYPO_relaxed.owl FYPO:0007673 biolink:NamedThing abolished invertase activity A molecular function phenotype in which invertase activity (beta-fructofuranosidase activity) is absent. FYPO_relaxed.owl FYPO:0007805 biolink:NamedThing abolished H3-H4 dimer loading onto DNA A molecular function phenotype in which the ATP hydrolysis-dependent activity that loads H3-H4 histone dimers onto DNA is absent. FYPO_relaxed.owl FYPO:0007842 biolink:NamedThing abolished peptide alpha-N-acetyltransferase activity A molecular function phenotype in which the observed rate of peptide alpha-N-acetyltransferase activity is absent. FYPO_relaxed.owl FYPO:0008276 biolink:NamedThing abolished polyphosphatase activity A molecular function phenotype in which a polyphosphatase activity is absent. FYPO_relaxed.owl FYPO:0000672 biolink:NamedThing normal cell morphology A cell phenotype characterized by normal cell morphology (i.e. size, shape, and structure). FYPO_relaxed.owl FYPO:0001076 biolink:NamedThing normal level of substance in cell A cell phenotype in which the amount of a specific substance measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001233 biolink:NamedThing normal subcellular component A cell phenotype in which the amount, distribution, composition or morphology of a cell part is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007711 biolink:NamedThing normal number of Ssb1 foci A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Ssb1 accumulates normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007724 biolink:NamedThing normal ERMES foci A cell phenotype observed in the vegetative growth phase of the life cycle in which the ERMES foci in a cell are normal (i.e. indistinguishable from wild type) in number, size, and distribution. An ERMES focus is a site that contains one or more ERMES complex(es). FYPO_relaxed.owl FYPO:0004249 biolink:NamedThing abnormal protein localization to vacuolar membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuolar membrane is abnormal. FYPO_relaxed.owl FYPO:0005491 biolink:NamedThing decreased maintenance of protein localization in vacuole, with protein secreted A cell phenotype observed in the vegetative growth phase of the life cycle in which the maintenance of protein localization in vacuole occurs to a lower extent than normal, and some of the protein is secreted, i.e. some of a protein that normally resides in the vacuole is instead secreted. FYPO_relaxed.owl FYPO:0005492 biolink:NamedThing abolished maintenance of protein localization in vacuole, with protein secreted A cell phenotype observed in the vegetative growth phase of the life cycle in which the maintenance of protein localization in vacuole does not occur, and some of the protein is secreted, i.e. a protein that normally resides in the vacuole is instead secreted. FYPO_relaxed.owl FYPO:0006292 biolink:NamedThing abolished protein localization to vacuole, with protein mislocalized to cytosol A cell phenotype observed in the vegetative growth phase of the life cycle in which protein localization to the vacuole does not occur, and the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0000681 biolink:NamedThing abnormal sporulation resulting in formation of two-spore ascus A sporulation phenotype that results in the formation of an ascus that has abnormal morphology and contains two diploid spores. FYPO_relaxed.owl FYPO:0003066 biolink:NamedThing abnormal sporulation resulting in formation of ascus with fewer than four spores A sporulation phenotype in which asci that contain one, two, or three spores form following conjugation and subsequent sporulation. FYPO_relaxed.owl FYPO:0004077 biolink:NamedThing abnormal sporulation resulting in formation of ascus with single large spore A sporulation phenotype that results in the formation of an ascus that contains a single spore that is larger than normal. FYPO_relaxed.owl FYPO:0000688 biolink:NamedThing decreased peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity A molecular function phenotype in which the observed rate of peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity is decreased. FYPO_relaxed.owl FYPO:0000793 biolink:NamedThing abnormal glycerol dehydrogenase activity A molecular function phenotype in which the observed rate of glycerol dehydrogenase activity is abnormal. FYPO_relaxed.owl FYPO:0000915 biolink:NamedThing abnormal pyruvate dehydrogenase activity A molecular function phenotype in which the observed rate of pyruvate dehydrogenase activity is abnormal. FYPO_relaxed.owl FYPO:0000922 biolink:NamedThing abnormal isocitrate dehydrogenase (NAD+) activity A molecular function phenotype in which the observed rate of isocitrate dehydrogenase (NAD+) activity is abnormal. FYPO_relaxed.owl FYPO:0000982 biolink:NamedThing abnormal glutamate dehydrogenase (NADP+) activity A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAPD+ as a cofactor is abnormal. FYPO_relaxed.owl FYPO:0001415 biolink:NamedThing abnormal sulfide:quinone oxidoreductase activity A molecular function phenotype in which the observed rate of sulfide:quinone oxidoreductase activity is abnormal. FYPO_relaxed.owl FYPO:0001674 biolink:NamedThing abnormal L-aminoadipate-semialdehyde dehydrogenase activity A molecular function phenotype in which the observed rate of L-aminoadipate-semialdehyde dehydrogenase activity is abnormal. FYPO_relaxed.owl FYPO:0001847 biolink:NamedThing abnormal ferric-chelate reductase activity A molecular function phenotype in which the observed rate of ferric-chelate reductase activity is abnormal. FYPO_relaxed.owl FYPO:0002523 biolink:NamedThing abnormal NADPH-hemoprotein reductase activity A molecular function phenotype in which the observed rate of NADPH-hemoprotein reductase activity is abnormal. FYPO_relaxed.owl FYPO:0002621 biolink:NamedThing abnormal malate dehydrogenase (decarboxylating) (NAD+) activity A molecular function phenotype in which the observed rate of malate dehydrogenase (decarboxylating) (NAD+) activity is abnormal. FYPO_relaxed.owl FYPO:0002695 biolink:NamedThing abnormal methylenetetrahydrofolate reductase (NADPH) activity A molecular function phenotype in which the observed rate of methylenetetrahydrofolate reductase (NADPH) activity is abnormal. FYPO_relaxed.owl FYPO:0002726 biolink:NamedThing abnormal saccharopine dehydrogenase activity A molecular function phenotype in which the observed rate of saccharopine dehydrogenase activity is abnormal. FYPO_relaxed.owl FYPO:0003072 biolink:NamedThing abnormal primary amine oxidase activity A molecular function phenotype in which the observed rate of primary amine oxidase activity is abnormal. FYPO_relaxed.owl FYPO:0003322 biolink:NamedThing abnormal succinate dehydrogenase (ubiquinone) activity A molecular function phenotype in which the observed rate of succinate dehydrogenase (ubiquinone) activity is abnormal. FYPO_relaxed.owl FYPO:0003475 biolink:NamedThing abnormal arsenate reductase activity A molecular function phenotype in which the observed rate of arsenate reductase activity is abnormal. FYPO_relaxed.owl FYPO:0003733 biolink:NamedThing abnormal alcohol dehydrogenase activity A molecular function phenotype in which the observed rate of alcohol dehydrogenase activity is abnormal. FYPO_relaxed.owl FYPO:0003884 biolink:NamedThing abnormal NAD(P)H oxidase activity A molecular function phenotype in which the observed rate of NAD(P)H oxidase activity is abnormal. FYPO_relaxed.owl FYPO:0003948 biolink:NamedThing abnormal sulfite reductase activity A molecular function phenotype in which the observed rate of sulfite reductase activity is abnormal. FYPO_relaxed.owl FYPO:0003963 biolink:NamedThing abnormal glutathione disulfide oxidoreductase activity A molecular function phenotype in which the observed rate of a glutathione disulfide oxidoreductase activity is abnormal. FYPO_relaxed.owl FYPO:0003982 biolink:NamedThing abnormal disulfide oxidoreductase activity A molecular function phenotype in which the observed rate of disulfide oxidoreductase activity is abnormal. FYPO_relaxed.owl FYPO:0004145 biolink:NamedThing abnormal pyridoxine:NADP 4-dehydrogenase activity A molecular function phenotype in which the observed rate of pyridoxine:NADP 4-dehydrogenase activity is abnormal. FYPO_relaxed.owl FYPO:0004364 biolink:NamedThing abnormal dioxygenase activity A molecular function phenotype in which the observed rate of a dioxygenase activity is abnormal. FYPO_relaxed.owl FYPO:0005470 biolink:NamedThing abnormal glutamate synthase (NADH) activity A molecular function phenotype in which the observed rate of glutamate synthase activity using NADH as a cofactor is abnormal. FYPO_relaxed.owl FYPO:0000692 biolink:NamedThing abnormal DNA-1,N6-ethenoadenine N-glycosylase activity A molecular function phenotype in which the observed rate of DNA-1,N6-ethenoadenine N-glycosylase activity is abnormal. FYPO_relaxed.owl FYPO:0000697 biolink:NamedThing abnormal DNA-7-methylguanine glycosylase activity A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is abnormal. FYPO_relaxed.owl FYPO:0004277 biolink:NamedThing abnormal uracil DNA N-glycosylase activity A molecular function phenotype in which the observed rate of uracil DNA N-glycosylase activity is abnormal. FYPO_relaxed.owl FYPO:0004279 biolink:NamedThing abnormal hypoxanthine DNA N-glycosylase activity A molecular function phenotype in which the observed rate of hypoxanthine DNA N-glycosylase activity is abnormal. FYPO_relaxed.owl FYPO:0004281 biolink:NamedThing abnormal xanthine DNA N-glycosylase activity A molecular function phenotype in which the observed rate of xanthine DNA N-glycosylase activity is abnormal. FYPO_relaxed.owl FYPO:0004283 biolink:NamedThing abnormal oxanine DNA N-glycosylase activity A molecular function phenotype in which the observed rate of oxanine DNA N-glycosylase activity is abnormal. FYPO_relaxed.owl FYPO:0004676 biolink:NamedThing abnormal purine-specific mismatch base pair DNA N-glycosylase activity A molecular function phenotype in which the observed rate of purine-specific mismatch base pair DNA N-glycosylase activity is abnormal. FYPO_relaxed.owl FYPO:0000695 biolink:NamedThing increased DNA-1,N6-ethenoadenine N-glycosylase activity A molecular function phenotype in which the observed rate of DNA-1,N6-ethenoadenine N-glycosylase activity is increased. FYPO_relaxed.owl FYPO:0000700 biolink:NamedThing increased DNA-7-methylguanine glycosylase activity A molecular function phenotype in which the observed rate of DNA-7-methylguanine glycosylase activity is increased. FYPO_relaxed.owl FYPO:0000701 biolink:NamedThing abolished DNA damage checkpoint override in response to caffeine A cellular response phenotype in which caffeine does not override the DNA damage checkpoint (as it does in wild type cells), allowing mitotic cell cycle arrest to occur. FYPO_relaxed.owl FYPO:0001571 biolink:NamedThing increased protein-protein interaction A molecular function phenotype in which the binding of one protein to another occurs to a greater extent than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0001645 biolink:NamedThing decreased protein-protein interaction A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0001943 biolink:NamedThing abnormal microtubule binding A molecular function phenotype in which occurrence of microtubule binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005119 biolink:NamedThing altered protein binding specificity A molecular function phenotype in which a mutation causes a gene product to bind to one or more proteins with different specificity from normal. For example, a protein may bind to a protein in a mutant that it does not bind in wild type. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005785 biolink:NamedThing decreased duration of protein-protein interaction A molecular function phenotype in which the binding of one protein to another occurs for a shorter time than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0007157 biolink:NamedThing abnormal histone binding A molecular function phenotype in which occurrence of histone binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007385 biolink:NamedThing increased duration of protein-protein interaction A molecular function phenotype in which the binding of one protein to another occurs for a longer time than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0005188 biolink:NamedThing delayed onset of mitotic cell cycle arrest during cellular response to hydroxyurea A cellular process phenotype in which the occurrence of cell cycle arrest in response to hydroxyurea exposure begins later than normal. Normally, cell cycle progression is slowed or arrested transiently following exposure to hydroxyurea. FYPO_relaxed.owl FYPO:0001001 biolink:NamedThing abnormal cell cycle arrest at mitotic G2/M phase transition during nitrogen starvation A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition, instead of the normal G1 phase, when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0001112 biolink:NamedThing premature cell cycle arrest in mitotic G1 phase in response to nitrogen starvation A cellular process phenotype in which the occurrence of cell cycle arrest in response to nitrogen starvation occurs in G1 phase, but begins earlier than normal. FYPO_relaxed.owl FYPO:0003345 biolink:NamedThing abolished cell cycle arrest in mitotic G1 phase in response to nitrogen starvation A cellular process phenotype in which the occurrence of cell cycle arrest in response to nitrogen starvation does not occur; arrest normally occurs in G1 phase. FYPO_relaxed.owl FYPO:0004582 biolink:NamedThing increased cell cycle arrest in mitotic G1 phase in response to nitrogen starvation A cellular process phenotype in which cell cycle arrest in response to nitrogen starvation occurs in G1 phase, but its occurrence is increased. FYPO_relaxed.owl FYPO:0000728 biolink:NamedThing abnormal actin cortical patch assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch assembly is abnormal. FYPO_relaxed.owl FYPO:0000729 biolink:NamedThing delayed onset of actomyosin contractile ring assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring assembly begins later than normal. Contractile ring assembly is the part of cytokinesis in which the actomyosin contractile ring is formed of actin, myosin, and associated proteins. FYPO_relaxed.owl FYPO:0003339 biolink:NamedThing decreased rate of actomyosin contractile ring assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actomyosin contractile ring assembly is decreased. Contractile ring assembly is the part of cytokinesis in which the actomyosin contractile ring is formed of actin, myosin, and associated proteins. FYPO_relaxed.owl FYPO:0006186 biolink:NamedThing increased rate of actomyosin contractile ring assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of contractile ring assembly is increased. Contractile ring assembly is the part of cytokinesis in which the actomyosin contractile ring is formed of actin, myosin, and associated proteins. FYPO_relaxed.owl FYPO:0006327 biolink:NamedThing abnormal rate of protein exchange in medial cortical node A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein exchange in the medial cortical nodes is abnormal. Normally, myosin and other node proteins are turned over between the nodes and elsewhere at rates consistent for each protein. FYPO_relaxed.owl FYPO:0007211 biolink:NamedThing premature actomyosin contractile ring assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring assembly begins earlier than normal. Contractile ring assembly is the part of cytokinesis in which the actomyosin contractile ring is formed of actin, myosin, and associated proteins. FYPO_relaxed.owl FYPO:0000731 biolink:NamedThing abnormal protein localization to medial cortex during vegetative growth A cell phenotype in which the localization of a protein to the medial cortex is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000928 biolink:NamedThing abnormal protein localization to cell cortex during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is abnormal. FYPO_relaxed.owl FYPO:0000742 biolink:NamedThing abnormal protein localization to actin cortical patch A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is abnormal. FYPO_relaxed.owl FYPO:0000929 biolink:NamedThing decreased protein localization to cell cortex during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is decreased. FYPO_relaxed.owl FYPO:0000930 biolink:NamedThing abolished protein localization to cell cortex during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex does not occur. FYPO_relaxed.owl FYPO:0000935 biolink:NamedThing abnormal protein localization to cortical microtubule cytoskeleton during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical microtubule cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0001774 biolink:NamedThing abnormal protein localization to eisosome filament A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the eisosome filament is abnormal. FYPO_relaxed.owl FYPO:0006059 biolink:NamedThing abnormal protein localization to septin ring A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the septin ring is abnormal. FYPO_relaxed.owl FYPO:0006875 biolink:NamedThing abnormal protein localization to cell cortex of cell tip during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips is abnormal. FYPO_relaxed.owl FYPO:0007870 biolink:NamedThing abolished protein localization to lateral cell cortex, with protein mislocalized to cytoplasm, during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the lateral cell cortex is abolished, and the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0007871 biolink:NamedThing decreased protein localization to lateral cell cortex, with protein distributed in cell cortex, during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the lateral cortex of a cell is decreased, and some of the protein is detected distributed throughout the cell cortex. There may be little or no protein detected at the medial cortex. FYPO_relaxed.owl FYPO:0009059 biolink:NamedThing increased protein localization to cell cortex during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is increased. FYPO_relaxed.owl FYPO:0001373 biolink:NamedThing abnormal protein localization to medial cortex A cell phenotype in which the localization of a protein to the medial cortex is abnormal. FYPO_relaxed.owl FYPO:0001372 biolink:NamedThing abnormal protein localization to medial cortex in spores A cell phenotype in which the localization of a protein to the medial cortex of a spore is abnormal. FYPO_relaxed.owl FYPO:0002527 biolink:NamedThing increased duration of protein localization to cell division site A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to the cell division site for longer than normal. FYPO_relaxed.owl FYPO:0002528 biolink:NamedThing decreased duration of protein localization to cell division site A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to the cell division site for a shorter time than normal. FYPO_relaxed.owl FYPO:0002718 biolink:NamedThing abnormal protein localization to septum A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell septum is abnormal. FYPO_relaxed.owl FYPO:0002869 biolink:NamedThing decreased protein localization to cell division site A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is decreased. FYPO_relaxed.owl FYPO:0003946 biolink:NamedThing delayed onset of protein localization to cell division site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division begins later than normal. FYPO_relaxed.owl FYPO:0004655 biolink:NamedThing increased protein localization to cell division site A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is increased. FYPO_relaxed.owl FYPO:0006448 biolink:NamedThing decreased rate of protein localization from Golgi apparatus to cleavage furrow A cell phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, localization of a protein from the Golgi apparatus to the cleavage furrow ring is decreased. FYPO_relaxed.owl FYPO:0006880 biolink:NamedThing increased protein localization to center of cell division site A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the center (as observed end-on) of the site of cell division is increased. FYPO_relaxed.owl FYPO:0007829 biolink:NamedThing premature protein localization to cell division site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division begins earlier than normal. FYPO_relaxed.owl FYPO:0000732 biolink:NamedThing short bipolar mitotic spindle A spindle phenotype in which the mitotic spindle is shorter than normal. FYPO_relaxed.owl FYPO:0000735 biolink:NamedThing short meiotic spindle A spindle phenotype in which the meiotic spindle is shorter than normal. FYPO_relaxed.owl FYPO:0000733 biolink:NamedThing long mitotic spindle A spindle phenotype in which the mitotic spindle is longer than normal. FYPO_relaxed.owl FYPO:0001978 biolink:NamedThing bent mitotic spindle A spindle phenotype in which the mitotic spindle is not straight, but instead forms an angle where microtubules from opposite poles interdigitate. FYPO_relaxed.owl FYPO:0004236 biolink:NamedThing thin mitotic spindle midzone A spindle phenotype in which the mitotic spindle is not of uniform thickness, but instead the spindle midzone is thinner than normal. FYPO_relaxed.owl FYPO:0005721 biolink:NamedThing curved mitotic spindle during anaphase B A spindle phenotype in which the mitotic spindle is curved (i.e. follows a smooth bend rather than a straight line) during anaphase B. FYPO_relaxed.owl FYPO:0006346 biolink:NamedThing bipolar mitotic spindle with decreased, irregular thickness A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle has two poles and can elongate during anaphase, but has decreased and non-uniform thickness along its length. FYPO_relaxed.owl FYPO:0006884 biolink:NamedThing thick mitotic spindle during mitotic metaphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle is thicker than normal during mitotic metaphase. FYPO_relaxed.owl FYPO:0007123 biolink:NamedThing unbundled spindle during mitotic prophase A physical cellular phenotype observed during mitotic prophase (in the vegetative growth phase of the life cycle) in which the mitotic spindle has two poles, but spindle microtubules (MTs) are not aligned into parallel or anti-parallel bundles. Instead, MTs extend in random directions from the asters, and the spindle does not elongate. FYPO_relaxed.owl FYPO:0007981 biolink:NamedThing abnormal interpolar microtubule length distribution during anaphase B A physical cellular phenotype in which the distribution of lengths of interpolar microtubules in the mitotic spindle is abnormal during anaphase B. FYPO_relaxed.owl FYPO:0000736 biolink:NamedThing long meiotic spindle A spindle phenotype in which the meiotic spindle is longer than normal. FYPO_relaxed.owl FYPO:0003264 biolink:NamedThing overlapping meiosis I spindles A spindle phenotype in which the meiotic spindles in adjacent dividing nuclei overlap during meiosis I. The order of nuclei in the resulting ascus differs from normal as a result. FYPO_relaxed.owl FYPO:0004567 biolink:NamedThing fragmented spindle during meiosis II A cell phenotype which the spindle is broken into fragments during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0005961 biolink:NamedThing multipolar meiotic spindle A physical cellular phenotype in which a meiotic spindle forms with microtubules emanating from three or more poles. FYPO_relaxed.owl FYPO:0006390 biolink:NamedThing multiple meiotic spindles A physical cellular phenotype in which a cell contains more than one meiotic spindle during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0006391 biolink:NamedThing meiotic spindle absent from cell during meiosis A cell phenotype in which the cell does not contain a detectable meiotic spindle during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0006415 biolink:NamedThing overlapping meiosis II spindles A spindle phenotype in which the meiotic spindles in adjacent dividing nuclei overlap during meiosis II. FYPO_relaxed.owl FYPO:0007101 biolink:NamedThing bent spindle during meiosis I A spindle phenotype in which the meiotic spindle is not straight, but instead forms an angle where microtubules from opposite poles interdigitate, during meiosis I. FYPO_relaxed.owl FYPO:0007988 biolink:NamedThing long spindle microtubules protruding beyond spindle pole body during meiosis I A physical cellular phenotype observed in meiosis I in which cells form meotic spindle microtubules that are longer than normal, and extend beyond the spindle pole body. The protruding spindle microtubules are surrounded by an extension of the nuclear envelope. FYPO_relaxed.owl FYPO:0006096 biolink:NamedThing abnormal protein localization to actin cable A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cables is abnormal. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts. FYPO_relaxed.owl FYPO:0000743 biolink:NamedThing abnormal actin cortical patch internalization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch internalization is abnormal. Actin cortical patch internalization is the process in which the patch moves from the cell surface to the inside of the cell. FYPO_relaxed.owl FYPO:0002373 biolink:NamedThing abnormal actin cortical patch localization during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch localization is abnormal during mitosis. FYPO_relaxed.owl FYPO:0006176 biolink:NamedThing decreased rate of actin cortical patch localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin cortical patch localization is decreased. FYPO_relaxed.owl FYPO:0006177 biolink:NamedThing undirected actin cortical patch movement A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches move within the cell cortex in a less directed manner than normal. The rate of movement may be normal. FYPO_relaxed.owl FYPO:0000744 biolink:NamedThing normal protein localization to actin cortical patch A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001402 biolink:NamedThing normal protein localization to cell cortex during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001776 biolink:NamedThing normal protein localization to eisosome filament A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the eisosome filament is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002558 biolink:NamedThing normal protein localization to medial cortex during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003334 biolink:NamedThing normal protein localization to septin ring A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the septin ring is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007283 biolink:NamedThing normal protein localization to lateral cell cortex during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the lateral cell cortex is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007451 biolink:NamedThing normal protein localization to cell cortex of cell tip during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of the cell tip is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003441 biolink:NamedThing normal protein localization to actin cytoskeleton during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to all or part of the actin cytoskeleton is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006189 biolink:NamedThing normal protein localization to actin cable A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cables is normal (i.e. indistinguishable from wild type). Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts. FYPO_relaxed.owl FYPO:0000745 biolink:NamedThing delayed onset of actin cortical patch internalization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch internalization begins later than normal. Actin cortical patch internalization is the process in which the patch moves from the cell surface to the inside of the cell. FYPO_relaxed.owl FYPO:0000746 biolink:NamedThing abolished actin cortical patch internalization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch internalization does not occur. Actin cortical patch internalization is the process in which the patch moves from the cell surface to the inside of the cell. FYPO_relaxed.owl FYPO:0006091 biolink:NamedThing premature actin cortical patch internalization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch internalization begins earlier than normal. Actin cortical patch internalization is the process in which the patch moves from the cell surface to the inside of the cell. FYPO_relaxed.owl FYPO:0000770 biolink:NamedThing branched nuclear inner membrane A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear inner membrane forms branched structures that extend into the nuclear lumen. FYPO_relaxed.owl FYPO:0000772 biolink:NamedThing perforated nuclear envelope A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which perforations or gaps (other than nuclear pores) are present in the nuclear envelope. FYPO_relaxed.owl FYPO:0001556 biolink:NamedThing excess nuclear envelope present A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more nuclear envelope than normal. Excess nuclear envelopes may take the form of intranuclear membrane stacks or invaginations, or small cytoplasmic spheres that are attached to the nucleus, have double lipid bilayer membranes, and may contain structures resembling nuclear pores. FYPO_relaxed.owl FYPO:0002005 biolink:NamedThing lobate nuclear envelope A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear envelope has a lobate cross-section, i.e. one in which the edge has deep indentations or undulations that form lobes. FYPO_relaxed.owl FYPO:0003779 biolink:NamedThing abnormal nuclear envelope morphology during mitosis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of all or part of the nuclear envelope is abnormal during mitosis. FYPO_relaxed.owl FYPO:0003975 biolink:NamedThing fragmented nuclear envelope A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear envelope is broken into multiple small fragments, none of which completely surrounds the contents of the nucleus. FYPO_relaxed.owl FYPO:0004725 biolink:NamedThing nuclear envelope protrusion present during mitotic interphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear envelope has one or more extensions that protrude into the cytoplasm during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006019 biolink:NamedThing karmellae present A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which excess endoplasmic reticulum (ER) membrane forms stacks adjacent to the nucleus, known as karmellae. FYPO_relaxed.owl FYPO:0006928 biolink:NamedThing nuclear membrane blebbing A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which one or both nuclear membrane(s) form blebs. Membrane blebbing usually leads to decreases in nuclear size and the nucleus:cytoplasm volume ratio. FYPO_relaxed.owl FYPO:0008140 biolink:NamedThing dilated nuclear envelope lumen An abnormal nuclear envelope morpbology in the vegetative growth phase of the life cycle in which the nuclear envelope lumen is larger than normal. FYPO_relaxed.owl FYPO:0000838 biolink:NamedThing normal protein localization to nucleus during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001509 biolink:NamedThing normal protein localization to chromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001587 biolink:NamedThing normal protein localization to cell tip during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001788 biolink:NamedThing normal protein localization to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to all or part of the cytoplasm is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002332 biolink:NamedThing normal protein localization to Golgi apparatus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002396 biolink:NamedThing normal maintenance of protein localization to heterochromatin at centromere outer repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the maintenance of localization of a protein at a location in heterochromatin at centromere outer repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002442 biolink:NamedThing normal protein localization to cell division site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002554 biolink:NamedThing normal protein localization to double-strand break site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a region of a chromosome at which a DNA double-strand break has occurred is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002574 biolink:NamedThing normal protein localization to centromere during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the centromere of a chromosome is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002575 biolink:NamedThing normal protein localization to chromosome at long terminal repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein a region in a chromosome that contains one or more long terminal repeats (LTRs) is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002625 biolink:NamedThing normal protein localization to rDNA A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to parts of the chromosome containing ribosomal DNA is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002887 biolink:NamedThing normal protein localization to telomere during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the telomere of a chromosome is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003184 biolink:NamedThing normal protein localization to cytoskeleton during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoskeleton is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003185 biolink:NamedThing normal protein localization to microtubule cytoskeleton during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0003768 biolink:NamedThing normal protein localization to mitochondrion A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004328 biolink:NamedThing normal protein localization during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cellular protein localization is normal (i.e. indistinguishable from wild type) during mitosis. FYPO_relaxed.owl FYPO:0005114 biolink:NamedThing normal protein localization to endosome A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endosome(s) is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005146 biolink:NamedThing normal proteasome localization to nuclear periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a proteasome to the nuclear periphery is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005572 biolink:NamedThing normal protein localization to cell periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell periphery is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005709 biolink:NamedThing normal protein localization to mitotic spindle pole body during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is normal (i.e. indistinguishable from wild type) during mitosis. FYPO_relaxed.owl FYPO:0005779 biolink:NamedThing normal protein localization to kinetochore during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during mitosis. FYPO_relaxed.owl FYPO:0005894 biolink:NamedThing normal protein localization to chromatin during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type) during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006002 biolink:NamedThing normal protein localization to P-bodies A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to P-bodies is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006080 biolink:NamedThing normal protein localization to nuclear exosome focus during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to nuclear exosome foci is normal (i.e. indistinguishable from wild type). Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle, such as Mmi1, Iss10, and Red1. FYPO_relaxed.owl FYPO:0006378 biolink:NamedThing normal protein localization to endoplasmic reticulum during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006594 biolink:NamedThing normal gamma-tubulin complex localization to mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which localization of the gamma-tubulin complex to the spindle pole body is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006635 biolink:NamedThing normal protein localization to cell tip during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006722 biolink:NamedThing normal protein localization to Cdr2 medial cortical node complex A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Cdr2 medial cortical node complex is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006724 biolink:NamedThing normal protein exit from Cdr2 medial cortical node complex during cellular response to osmotic stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which movement of a protein away from Cdr2 medial cortical node complexes during a cellular response to osmotic stress is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006999 biolink:NamedThing normal dynamic protein localization pattern A cell phenotype in which a protein that is normally dynamically localized to a specific place in the cell shows a normal (i.e. indistinguishable from wild type) temporal pattern of localization. For example, a protein may move to or from the location more or less frequently than normal. FYPO_relaxed.owl FYPO:0007028 biolink:NamedThing normal protein localization to medial cortex septin ring during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the septin ring at the medial cortex is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007058 biolink:NamedThing normal protein localization to vacuole A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007133 biolink:NamedThing normal protein localization to medial cortical node during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007181 biolink:NamedThing normal protein localization to cell division site during mitotic anaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is normal (i.e. indistinguishable from wild type) during anaphase of mitosis. FYPO_relaxed.owl FYPO:0007441 biolink:NamedThing normal protein localization to endoplasmic reticulum-plasma membrane contact site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to endoplasmic reticulum-plasma membrane contact sites is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007725 biolink:NamedThing normal protein localization to late endosome A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to late endosomes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007815 biolink:NamedThing normal protein localization to protein aggregate center A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to protein aggregate centers is normal (i.e. indistinguishable from wild type). Protein aggregate centers are composed of chaperones and misfolded proteins, and are reversibly formed in the nucleus and cytosol to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding. FYPO_relaxed.owl FYPO:0000774 biolink:NamedThing decreased pre-replicative complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of pre-replicative complex assembly is decreased. FYPO_relaxed.owl FYPO:0003499 biolink:NamedThing increased rate of pre-replicative complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of pre-replicative complex assembly is increased. FYPO_relaxed.owl FYPO:0002679 biolink:NamedThing decreased protein phosphorylation A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0002680 biolink:NamedThing increased protein phosphorylation A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005033 biolink:NamedThing abnormal protein phosphorylation during nitrogen starvation A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, is abnormal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006765 biolink:NamedThing abnormal protein phosphorylation during meiotic cell cycle A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, is abnormal during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0007410 biolink:NamedThing abnormal RNA polymerase II C-terminal domain phosphorylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more residues within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II is abnormal. FYPO_relaxed.owl FYPO:0000776 biolink:NamedThing normal protein phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001909 biolink:NamedThing normal protein glycosylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein glycosylation is normal (i.e. indistinguishable from wild type). Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid. FYPO_relaxed.owl FYPO:0001922 biolink:NamedThing normal protein dephosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein dephosphorylation is normal (i.e. indistinguishable from wild type). Protein dephosphorylation is the removal of a phosphate group from a protein amino acid. FYPO_relaxed.owl FYPO:0002013 biolink:NamedThing normal protein oxidation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein oxidation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002502 biolink:NamedThing normal protein palmitoylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein palmitoylation is normal (i.e. indistinguishable from wild type). Protein palmitoylation is the addition of a palmitoyl group to a protein amino acid. FYPO_relaxed.owl FYPO:0002600 biolink:NamedThing normal histone modification during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone modification is normal. All histone modification may be assayed, or modification of specific sites on specific histones may be measured. FYPO_relaxed.owl FYPO:0002635 biolink:NamedThing normal protein ubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the ubiquitination of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003362 biolink:NamedThing normal protein acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein acetylation is normal (i.e. indistinguishable from wild type). Protein acetylation is the addition of an acetyl group to a protein amino acid. FYPO_relaxed.owl FYPO:0005196 biolink:NamedThing normal protein polyubiquitination during cellular response to UV A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the polyubiquitination of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type) when the cell is exposed to ultraviolet light. FYPO_relaxed.owl FYPO:0005675 biolink:NamedThing normal protein deubiquitination following cellular response to methyl methanesulfonate during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the deubiquitination of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type) after cells have been exposed to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0005818 biolink:NamedThing normal protein neddylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the neddylation of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006124 biolink:NamedThing normal asymmetric protein arginine dimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine in one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006887 biolink:NamedThing normal protein sumoylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the sumoylation of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004423 biolink:NamedThing normal protein threonine phosphorylation A cellular process phenotype in which the phosphorylation of threonine residues of one or more specific proteins is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005035 biolink:NamedThing normal protein phosphorylation during nitrogen starvation A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0000777 biolink:NamedThing abnormal double-strand break repair during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair is abnormal. FYPO_relaxed.owl FYPO:0003173 biolink:NamedThing abnormal nucleotide-excision repair during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleotide-excision repair is abnormal. Nucleotide-excision repair is a DNA repair process in which a small region of the strand surrounding the damage is removed as an oligonucleotide, and the resulting small gap is filled in by the sequential action of DNA polymerase and DNA ligase. FYPO_relaxed.owl FYPO:0003892 biolink:NamedThing abnormal error-prone translesion synthesis A cell phenotype observed in the vegetative growth phase of the life cycle in which error-prone translesion synthesis is abnormal. Error-prone translesion synthesis a DNA repair process that results in the conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. FYPO_relaxed.owl FYPO:0004031 biolink:NamedThing decreased UV-damage excision repair A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UV-damage excision repair occurs to a lower extent than normal. UV-damage excision repair is a DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site, and that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs). FYPO_relaxed.owl FYPO:0004061 biolink:NamedThing decreased UV-damage excision repair during mitotic G1 phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UV-damage excision repair occurs to a lower extent than normal during G1 phase of the mitotic cell cycle. UV-damage excision repair is a DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site, and that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs). FYPO_relaxed.owl FYPO:0005323 biolink:NamedThing abnormal error-free translesion synthesis A cell phenotype observed in the vegetative growth phase of the life cycle in which error-free translesion synthesis is abnormal. Error-free translesion synthesis a DNA repair process that results in the conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across from the lesion. FYPO_relaxed.owl FYPO:0005428 biolink:NamedThing delayed onset of UV-damage excision repair A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UV-damage excision repair begins later than normal. UV-damage excision repair is a DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site, and that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs). FYPO_relaxed.owl FYPO:0005429 biolink:NamedThing decreased UV-damage excision repair during mitotic G2 phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UV-damage excision repair occurs to a lower extent than normal during G2 phase of the mitotic cell cycle. UV-damage excision repair is a DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site, and that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs). FYPO_relaxed.owl FYPO:0000778 biolink:NamedThing delayed onset of double-strand break repair A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair begins later than normal. FYPO_relaxed.owl FYPO:0002553 biolink:NamedThing abnormal double-strand break processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break processing is abnormal. Double-strand break processing is the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang. FYPO_relaxed.owl FYPO:0003584 biolink:NamedThing increased double-strand break repair via nonhomologous end joining A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of double-strand break repair via nonhomologous end joining (NHEJ) is increased. NHEJ is the repair of double-strand breaks in DNA in which the two broken ends are rejoined with little or no sequence complementarity. FYPO_relaxed.owl FYPO:0003660 biolink:NamedThing decreased double-strand break repair during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0003661 biolink:NamedThing abnormal double-strand break repair via nonhomologous end joining A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of double-strand break repair via nonhomologous end joining (NHEJ) is abnormal. NHEJ is the repair of double-strand breaks in DNA in which the two broken ends are rejoined with little or no sequence complementarity. FYPO_relaxed.owl FYPO:0003662 biolink:NamedThing increased error-free double-strand break repair A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of double-strand break repair via an error-free mechanism, such as homologous recombination or break-induced replication, is increased. FYPO_relaxed.owl FYPO:0003928 biolink:NamedThing altered double-strand break repair junction in presence of persistent double-strand breaks A cell phenotype in which the repair of double-strand breaks in DNA that are continually made (for example, by constitutive expression of a nuclease) results in repair junctions that differ from wild type. FYPO_relaxed.owl FYPO:0007455 biolink:NamedThing increased double-strand break repair via single-strand annealing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of double-strand break repair via single-strand annealing is increased. FYPO_relaxed.owl FYPO:0000779 biolink:NamedThing inviable elongated vegetative cell with central constriction A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is longer than normal and has an abnormal shape featuring a constriction at the center of the cell, corresponding to the cell division site. In some such cells, the diameter at the ends is much greater than in wild-type cells. FYPO_relaxed.owl FYPO:0002049 biolink:NamedThing elongated multinucleate aseptate vegetative cell A cell morphology phenotype in which a vegetative cell is elongated, has no septum, and contains more than one nucleus. FYPO_relaxed.owl FYPO:0005773 biolink:NamedThing elongated mononucleate aseptate vegetative cell A cell morphology phenotype in which a vegetative cell is elongated, has no septum, and contains one nucleus. FYPO_relaxed.owl FYPO:0002875 biolink:NamedThing increased transcription A cellular process phenotype in which transcription occurs to a greater extent than normal. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002878 biolink:NamedThing increased transcription during glucose starvation A cellular process phenotype in which transcription occurs to a greater extent than normal when the cell is subject to glucose starvation. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0005661 biolink:NamedThing increased transcription during nitrogen starvation A cellular process phenotype in which transcription occurs to a greater extent than normal when the cell is subject to nitrogen starvation. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0005662 biolink:NamedThing increased transcription from TR box A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more TR boxes occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005917 biolink:NamedThing increased subtelomeric heterochromatin RNA level A cell phenotype in which the amount of RNA derived from subtelomeric heterochromatin regions is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0007421 biolink:NamedThing increased transcription at telomere during G0 A cellular process phenotype in which transcription occurs to a greater extent than normal in telomeric regions during G0 phase. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0007787 biolink:NamedThing increased transcription during cell cycle arrest at meiotic G2/MI transition A cellular process phenotype in which transcription occurs to a greater extent than normal when the meiotic cell cycle is arrested at the G2/MI phase transition. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002876 biolink:NamedThing decreased transcription A cellular process phenotype in which transcription occurs to a lower extent than normal. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0003120 biolink:NamedThing decreased transcription during glucose starvation A cellular process phenotype in which transcription occurs to a lower extent than normal when the cell is subject to glucose starvation. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0005118 biolink:NamedThing decreased transcription during nitrogen starvation A cellular process phenotype in which transcription occurs to a lower extent than normal when the cell is subject to nitrogen starvation. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0000782 biolink:NamedThing mislocalized protein during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is observed in a particular location where it is not normally found. FYPO_relaxed.owl FYPO:0001158 biolink:NamedThing normal cellular pH A cell phenotype observed in the vegetative growth phase of the life cycle in which the measured intracellular pH is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001221 biolink:NamedThing normal nucleus:cytoplasm ratio A cell phenotype observed in the vegetative growth phase of the life cycle in which the ratio of the nuclear volume to the total cell volume is in the same range as wild type (approximately 0.076-0.089). FYPO_relaxed.owl FYPO:0001793 biolink:NamedThing resistant to cell wall digestion A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell shows increased resistance to conditions that degrade the cell wall. FYPO_relaxed.owl FYPO:0001840 biolink:NamedThing increased minichromosome loss during vegetative growth A cell phenotype in which minichromosomes are lost at a higher frequency than normal during the vegetative growth phase of the life cycle. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation. FYPO_relaxed.owl FYPO:0003039 biolink:NamedThing decreased RNA stability during cellular response to UV A cell phenotype in which RNA stability is decreased during a cellular response to ultraviolet light. RNA molecules are more likely to degrade over a given time period than in wild type. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0006861 biolink:NamedThing mislocalized RNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which an RNA is observed in a particular location where it is not normally found. FYPO_relaxed.owl FYPO:0003453 biolink:NamedThing protein mislocalized to nucleus A cell phenotype in which a protein that is not normally found in the nucleus is observed there. FYPO_relaxed.owl FYPO:0004447 biolink:NamedThing protein mislocalized to prospore membrane A cell phenotype in which a protein that is not normally found in the prospore membrane is observed there. FYPO_relaxed.owl FYPO:0004448 biolink:NamedThing mislocalized protein during meiotic cell cycle A cell phenotype in which a protein is observed in a particular location where it is not normally found during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0004842 biolink:NamedThing protein mislocalized to cytoplasm A cell phenotype observed in which a protein that is not normally found in the cytoplasm is observed there. FYPO_relaxed.owl FYPO:0006590 biolink:NamedThing protein mislocalized to endoplasmic reticulum A cell phenotype in which a protein that is not normally found in the endoplasmic reticulum is observed there. FYPO_relaxed.owl FYPO:0000783 biolink:NamedThing protein mislocalized to cytoplasm during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the cytoplasm is observed there. FYPO_relaxed.owl FYPO:0000784 biolink:NamedThing protein mislocalized to nucleus during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the nucleus is observed there. FYPO_relaxed.owl FYPO:0001796 biolink:NamedThing protein mislocalized to centromere A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the centromeric region of a chromosome is observed there. FYPO_relaxed.owl FYPO:0002444 biolink:NamedThing loss of punctate cytoplasmic protein localization A cell phenotype in which a protein that is normally localized to discrete regions in the cytoplasm, visible as foci or dots by microscopy, is abnormally localized such that dots cannot be observed. FYPO_relaxed.owl FYPO:0002445 biolink:NamedThing protein mislocalized to actin cortical patch A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in actin cortical patches is observed there. FYPO_relaxed.owl FYPO:0002624 biolink:NamedThing decreased punctate nuclear protein localization A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that fewer dots are observed than in normal (wild type) cells. FYPO_relaxed.owl FYPO:0002851 biolink:NamedThing protein mislocalized to eisosome A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the eisosome is observed there. FYPO_relaxed.owl FYPO:0003187 biolink:NamedThing protein mislocalized to astral microtubule during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found associated with astral microtubules during mitosis is observed there during mitosis. The protein may or may not normally associate with astral microtubules during other cell cycle phases. FYPO_relaxed.owl FYPO:0003482 biolink:NamedThing increased punctate cytoplasmic protein localization A cell phenotype in which a protein is localized to discrete regions in the cytoplasm, visible as foci or dots by microscopy, to a greater extent observed than in normal (wild type) cells. FYPO_relaxed.owl FYPO:0003527 biolink:NamedThing protein mislocalized to cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the cell tip is observed there. FYPO_relaxed.owl FYPO:0003528 biolink:NamedThing protein mislocalized to actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the actomyosin contractile ring is observed there. FYPO_relaxed.owl FYPO:0005116 biolink:NamedThing increased punctate nuclear protein localization A cell phenotype in which a protein is localized to discrete regions in the nucleus, visible as foci or dots by microscopy, to a greater extent observed than in normal (wild type) cells. FYPO_relaxed.owl FYPO:0006119 biolink:NamedThing protein mislocalized to actin cable A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in or on actin cables is observed there. FYPO_relaxed.owl FYPO:0006344 biolink:NamedThing protein mislocalized to plasma membrane during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the plasma membrane is observed there. FYPO_relaxed.owl FYPO:0006636 biolink:NamedThing mislocalized protein distributed in cell cortex A cell phenotype in which a protein is detected abnormally distributed throughout the cell cortex. The protein may normally be restricted to part of the cell cortex, or not normally located in the cell cortex at all. FYPO_relaxed.owl FYPO:0006637 biolink:NamedThing decreased protein localization to cell cortex of cell tip, with protein distributed in cortex A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips is decreased, and an increased amount of the protein is instead detected distributed throughout the cell cortex. FYPO_relaxed.owl FYPO:0007405 biolink:NamedThing abnormal protein localization to medial cortex, with protein distributed in cell cortex, during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is abnormal, and some of the protein is detected distributed throughout the cell cortex. There may be little or no protein detected at the medial cortex. FYPO_relaxed.owl FYPO:0007799 biolink:NamedThing protein mislocalized to cell surface during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the cell surface is observed there. FYPO_relaxed.owl FYPO:0006862 biolink:NamedThing RNA mislocalized to cytoplasm during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which an RNA that is not normally found in the cytoplasm is observed there. FYPO_relaxed.owl FYPO:0006947 biolink:NamedThing protein mislocalized to cytoplasm during glucose starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the cytoplasm is observed there when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0003454 biolink:NamedThing protein mislocalized to nucleus during meiosis I A cell phenotype in which a protein that is not normally found in the nucleus is observed there during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0004841 biolink:NamedThing protein mislocalized to nucleus during glucose starvation A cell phenotype in which a protein that is not normally found in the nucleus is observed there when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0008126 biolink:NamedThing cytoplasmic protein mislocalized to nucleoplasm during mitotic M-phase A cell phenotype in which a protein that is normally found only in the cytoplasm is observed in the nucleoplasm during mitotic M-phase. FYPO_relaxed.owl FYPO:0000787 biolink:NamedThing abnormal histone H3-K9 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 is abnormal. FYPO_relaxed.owl FYPO:0000866 biolink:NamedThing abnormal histone H3-K9 dimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 is abnormal. FYPO_relaxed.owl FYPO:0000871 biolink:NamedThing increased histone H3-K9 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000872 biolink:NamedThing decreased histone H3-K9 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0002566 biolink:NamedThing abolished histone H3-K9 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 does not occur. FYPO_relaxed.owl FYPO:0003096 biolink:NamedThing decreased histone H3-K9 methylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005066 biolink:NamedThing increased histone H3-K9 methylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in centromeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006077 biolink:NamedThing increased histone H3-K9 methylation at rDNA during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 9 of histone H3 occurs to a greater extent than normal at ribosomal DNA. FYPO_relaxed.owl FYPO:0006403 biolink:NamedThing abolished histone H3-K36 dimethylation at promoter during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 36 of histone H3 in one or more promoter regions does not occur. FYPO_relaxed.owl FYPO:0000788 biolink:NamedThing abnormal histone H3-K14 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 is abnormal. FYPO_relaxed.owl FYPO:0000891 biolink:NamedThing abnormal histone H3-K9 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 is abnormal. FYPO_relaxed.owl FYPO:0002362 biolink:NamedThing decreased histone H3 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3 acetylation occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0002363 biolink:NamedThing increased histone H3 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3 acetylation occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005534 biolink:NamedThing decreased histone H4-K16 acetylation at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 in telomeric regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006449 biolink:NamedThing decreased rate of histone H3 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of histone H3 acetylation is lower extent than normal. FYPO_relaxed.owl FYPO:0000791 biolink:NamedThing abnormal actin cortical patch morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of actin cortical patches is abnormal. FYPO_relaxed.owl FYPO:0001881 biolink:NamedThing elongated actin filaments A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin filaments that are longer than normal. FYPO_relaxed.owl FYPO:0002031 biolink:NamedThing abnormal actin cable morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of actin cables is abnormal. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts. FYPO_relaxed.owl FYPO:0005853 biolink:NamedThing aggregated filamentous actin in cytoplasm A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which filamentous actin (F-actin) is present in the cytoplasm in the form of dense, irregularly shaped aggregates. FYPO_relaxed.owl FYPO:0006802 biolink:NamedThing dispersed filamentous actin A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which filamentous actin (F-actin) is present in a dispersed form in the cell. Normal F-actin structures (cables and cortical patches) may or may not also be present. FYPO_relaxed.owl FYPO:0004964 biolink:NamedThing actin cortical patches present in decreased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer actin cortical patches than normal. FYPO_relaxed.owl FYPO:0004972 biolink:NamedThing actin cortical patches present in increased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more actin cortical patches than normal. FYPO_relaxed.owl FYPO:0000795 biolink:NamedThing decreased glycerol dehydrogenase activity A molecular function phenotype in which the observed rate of glycerol dehydrogenase activity is decreased. FYPO_relaxed.owl FYPO:0000916 biolink:NamedThing decreased pyruvate dehydrogenase activity A molecular function phenotype in which the observed rate of pyruvate dehydrogenase activity is decreased. FYPO_relaxed.owl FYPO:0000983 biolink:NamedThing decreased glutamate dehydrogenase (NADP+) activity A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAPD+ as a cofactor is decreased. FYPO_relaxed.owl FYPO:0001416 biolink:NamedThing decreased sulfide:quinone oxidoreductase activity A molecular function phenotype in which the observed rate of sulfide:quinone oxidoreductase activity is decreased. FYPO_relaxed.owl FYPO:0001938 biolink:NamedThing decreased cytochrome-c oxidase activity A molecular function phenotype in which the observed rate of cytochrome-c oxidase activity is decreased. FYPO_relaxed.owl FYPO:0001940 biolink:NamedThing decreased ubiquinol-cytochrome-c reductase activity A molecular function phenotype in which the observed rate of ubiquinol-cytochrome-c reductase activity is decreased. FYPO_relaxed.owl FYPO:0002622 biolink:NamedThing decreased malate dehydrogenase (decarboxylating) (NAD+) activity A molecular function phenotype in which the observed rate of malate dehydrogenase (decarboxylating) (NAD+) activity is decreased. FYPO_relaxed.owl FYPO:0002697 biolink:NamedThing decreased methylenetetrahydrofolate reductase (NADPH) activity A molecular function phenotype in which the observed rate of methylenetetrahydrofolate reductase (NADPH) activity is decreased. FYPO_relaxed.owl FYPO:0003073 biolink:NamedThing decreased primary amine oxidase activity A molecular function phenotype in which the observed rate of primary amine oxidase activity is decreased. FYPO_relaxed.owl FYPO:0003282 biolink:NamedThing decreased superoxide dismutase activity A molecular function phenotype in which the observed rate of superoxide dismutase activity is decreased. FYPO_relaxed.owl FYPO:0003321 biolink:NamedThing decreased NADH dehydrogenase (ubiquinone) activity A molecular function phenotype in which the observed rate of NADH dehydrogenase (ubiquinone) activity is decreased. FYPO_relaxed.owl FYPO:0003387 biolink:NamedThing decreased catalase activity A molecular function phenotype in which the observed rate of catalase activity is decreased. FYPO_relaxed.owl FYPO:0003476 biolink:NamedThing decreased arsenate reductase activity A molecular function phenotype in which the observed rate of arsenate reductase activity is decreased. FYPO_relaxed.owl FYPO:0003734 biolink:NamedThing decreased alcohol dehydrogenase activity A molecular function phenotype in which the observed rate of alcohol dehydrogenase activity is decreased. FYPO_relaxed.owl FYPO:0003885 biolink:NamedThing decreased NAD(P)H oxidase activity A molecular function phenotype in which the observed rate of NAD(P)H oxidase activity is decreased. FYPO_relaxed.owl FYPO:0003949 biolink:NamedThing decreased sulfite reductase activity A molecular function phenotype in which the observed rate of sulfite reductase activity is decreased. FYPO_relaxed.owl FYPO:0003964 biolink:NamedThing decreased glutathione disulfide oxidoreductase activity A molecular function phenotype in which the observed rate of a glutathione disulfide oxidoreductase activity is decreased. FYPO_relaxed.owl FYPO:0004130 biolink:NamedThing decreased succinate dehydrogenase (ubiquinone) activity A molecular function phenotype in which the observed rate of succinate dehydrogenase (ubiquinone) activity is decreased. FYPO_relaxed.owl FYPO:0004146 biolink:NamedThing decreased pyridoxine:NADP 4-dehydrogenase activity A molecular function phenotype in which the observed rate of pyridoxine:NADP 4-dehydrogenase activity is decreased. FYPO_relaxed.owl FYPO:0004873 biolink:NamedThing decreased 2-oxoglutarate dioxygenase activity A molecular function phenotype in which a 2-oxoglutarate-dependent dioxygenase activity is decreased. FYPO_relaxed.owl FYPO:0000816 biolink:NamedThing decreased concentration of substance in growth medium A phenotype in which the concentration of a substance released into the growth medium by cells is lower than normal. FYPO_relaxed.owl FYPO:0001156 biolink:NamedThing decreased pH of growth medium A phenotype in which cells cause the pH of their growth medium to decrease by a greater amount than normal. FYPO_relaxed.owl FYPO:0006540 biolink:NamedThing abnormal actin cytoskeleton organization during cellular response to pheromone A cellular process phenotype in which actin cytoskeleton organization is abnormal during a cellular response to pheromone. FYPO_relaxed.owl FYPO:0005900 biolink:NamedThing abnormal actin filament-based movement A cell phenotype observed in the vegetative growth phase of the life cycle in which actin filament-based movement is abnormal. Actin filament-based movement is the movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. FYPO_relaxed.owl FYPO:0006307 biolink:NamedThing decreased actin filament severing A cell phenotype observed in the vegetative growth phase of the life cycle in which actin filament severing is decreased. Actin filament severing is the process in which an actin filament is broken down into smaller filaments. FYPO_relaxed.owl FYPO:0000805 biolink:NamedThing abnormal endoplasmic reticulum organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which endoplasmic reticulum (ER) organization is abnormal. ER organization results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum. FYPO_relaxed.owl FYPO:0000806 biolink:NamedThing abnormal Golgi organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which Golgi organization is abnormal. Golgi organization results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. FYPO_relaxed.owl FYPO:0000815 biolink:NamedThing abnormal nuclear envelope organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear envelope organization is abnormal. Nuclear envelope organization results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope. FYPO_relaxed.owl FYPO:0002804 biolink:NamedThing abnormal vacuole organization during nitrogen starvation A cellular process phenotype in which vacuole organization is abnormal when the cell is subject to nitrogen starvation. Vacuole organization results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. FYPO_relaxed.owl FYPO:0006057 biolink:NamedThing abnormal vacuole fusion A cellular process phenotype in which vacuole fusion, the merging of two vacuole membranes to form a single vacuole, is abnormal. FYPO_relaxed.owl FYPO:0000814 biolink:NamedThing abnormal nucleolus organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleolus organization is abnormal. Nucleolus organization results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus. FYPO_relaxed.owl FYPO:0003973 biolink:NamedThing abnormal nuclear pore localization A localization phenotype observed in the vegetative growth phase of the life cycle in which nuclear pore localization is abnormal, resulting in an abnormal spatial arrangement of nuclear pores within the nuclear envelope. FYPO_relaxed.owl FYPO:0000818 biolink:NamedThing increased concentration of M-factor in growth medium A phenotype in which the concentration of M-factor, the mating pheromone produced by mating type minus cells, released into the growth medium is higher than normal. FYPO_relaxed.owl FYPO:0000819 biolink:NamedThing increased concentration of P-factor in growth medium A phenotype in which the concentration of P-factor, the mating pheromone produced by mating type plus cells, released into the growth medium is higher than normal. FYPO_relaxed.owl FYPO:0000820 biolink:NamedThing decreased concentration of pheromone in growth medium A phenotype in which the concentration of a peptide pheromone released into the growth medium by cells is lower than normal. FYPO_relaxed.owl FYPO:0000821 biolink:NamedThing decreased concentration of M-factor in growth medium A phenotype in which the concentration of M-factor, the mating pheromone produced by mating type minus cells, released into the growth medium is lower than normal. FYPO_relaxed.owl FYPO:0000822 biolink:NamedThing decreased concentration of P-factor in growth medium A phenotype in which the concentration of P-factor, the mating pheromone produced by mating type plus cells, released into the growth medium is lower than normal. FYPO_relaxed.owl FYPO:0000824 biolink:NamedThing altered RNA level A cell phenotype in which the amount of RNA measured in a cell differs from normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0000834 biolink:NamedThing altered protein level A cell phenotype in which the amount of protein measured in a cell differs from normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0000990 biolink:NamedThing increased level of substance in cell A cell phenotype in which the amount of a specific substance measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0000991 biolink:NamedThing decreased level of substance in cell A cell phenotype in which the amount of a specific substance measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001323 biolink:NamedThing altered level of substance in cell during vegetative growth A cell phenotype in which the amount of a specific substance measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001446 biolink:NamedThing altered cellular trehalose level A cell phenotype in which the amount of trehalose measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0001659 biolink:NamedThing altered cellular cAMP level A cell phenotype in which the amount of cyclic AMP measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0002142 biolink:NamedThing altered cellular reactive oxygen species level A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0004139 biolink:NamedThing altered level of substance in cell during nitrogen starvation A cell phenotype in which the amount of a specific substance measured in a cell that is subject to nitrogen starvation differs from normal. FYPO_relaxed.owl FYPO:0004320 biolink:NamedThing altered DNA level A cell phenotype in which the amount of DNA measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0006408 biolink:NamedThing altered cellular nitric oxide level A cell phenotype in which the amount of nitric oxide measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0007316 biolink:NamedThing altered level of macromolecular complex A physical cellular phenotype in which the amount of any macromolecular complex present in a cell differs from wild type. FYPO_relaxed.owl FYPO:0007492 biolink:NamedThing altered level of substance in cell wall A cell phenotype in which the amount of a specific substance measured in the cell wall differs from normal. FYPO_relaxed.owl FYPO:0001326 biolink:NamedThing altered RNA level during vegetative growth A cell phenotype in which the amount of RNA measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0003195 biolink:NamedThing altered RNA level during cellular response to phosphate starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell differs from normal during a cellular response to phosphate starvation. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0003196 biolink:NamedThing altered RNA level during cellular response to iron ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell differs from normal during a cellular response to iron ion starvation. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0003197 biolink:NamedThing altered RNA level during cellular response to copper ion starvation during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell differs from normal during a cellular response to copper ion starvation. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0003198 biolink:NamedThing altered RNA level during cellular response to osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell differs from normal during a cellular response to osmotic stress. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0003199 biolink:NamedThing altered RNA level during cellular response to glucose starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell differs from normal during a cellular response to glucose starvation. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0004363 biolink:NamedThing altered level of stress responsive gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more messenger RNAs that are normally expressed during a cellular response to stress measured in a cell differs from normal (i.e. is higher or lower than observed in wild-type cells during vegetative growth). FYPO_relaxed.owl FYPO:0005858 biolink:NamedThing altered level of translation gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more translation RNAs measured in a cell differs from normal (i.e. is higher or lower than observed in wild-type cells). Translation RNAs are transcribed from genes whose products are involved in translation. FYPO_relaxed.owl FYPO:0005996 biolink:NamedThing altered rRNA or precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any ribosomal RNA (rRNA) primary transcript, rRNA precursor or processing intermediate, or mature rRNA measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0005997 biolink:NamedThing altered snRNA or precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any small nuclear RNA (snRNA) primary transcript, snRNA precursor or processing intermediate, or mature snRNA measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0005998 biolink:NamedThing altered snoRNA or precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any small nucleolar RNA (snoRNA) primary transcript, snoRNA precursor or processing intermediate, or mature snoRNA measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0005999 biolink:NamedThing altered tRNA or precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any transfer RNA (tRNA) primary transcript, tRNA precursor or processing intermediate, or mature tRNA measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0006465 biolink:NamedThing altered mature ncRNA level during vegetative growth A cell phenotype in which the amount of mature non-coding RNA (ncRNA) measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total ncRNA or a specific ncRNA may be affected. FYPO_relaxed.owl FYPO:0008101 biolink:NamedThing altered tRNA level during vegetative growth A cell phenotype in which the amount of tRNA measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001890 biolink:NamedThing increased RNA level A cell phenotype in which the amount of RNA measured in a cell is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0002020 biolink:NamedThing increased RNA level during nitrogen starvation A cell phenotype in which the amount of RNA measured in a cell when the cell is subject to nitrogen starvation is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002945 biolink:NamedThing increased RNA level during G0 A cell phenotype in which the amount of RNA measured in a cell when the cell is in G0 phase is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003033 biolink:NamedThing increased RNA level during glucose starvation A cell phenotype in which the amount of RNA measured in a cell when the cell is subject to glucose starvation is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003991 biolink:NamedThing increased RNA level in stationary phase A cell phenotype in which the amount of RNA measured in a cell is higher than normal when the population in which the cell is found is in stationary phase. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0005120 biolink:NamedThing increased RNA level during meiotic cell cycle A cell phenotype in which the amount of RNA measured in a cell is greater than normal during the meiotic cell cycle. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0000826 biolink:NamedThing decreased RNA level A cell phenotype in which the amount of RNA measured in a cell is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0006208 biolink:NamedThing altered RNA level during cellular response to copper ion starvation A cell phenotype in which the amount of RNA measured in a cell differs from normal during a cellular response to copper ion starvation. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0000835 biolink:NamedThing decreased protein level A cell phenotype in which the amount of protein measured in a cell is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001447 biolink:NamedThing decreased cellular trehalose level A cell phenotype in which the amount of trehalose measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001660 biolink:NamedThing decreased cellular cAMP level A cell phenotype in which the amount of cyclic AMP measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001888 biolink:NamedThing substance absent from cell A cell phenotype in which the amount of a specific substance measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0002143 biolink:NamedThing decreased cellular reactive oxygen species level in stationary phase A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is lower than normal when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0002660 biolink:NamedThing decreased cellular trehalose 6-phosphate level A cell phenotype in which the amount of trehalose 6-phosphate measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0002780 biolink:NamedThing decreased cellular reactive oxygen species level during vegetative growth A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is lower than normal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0003521 biolink:NamedThing decreased cellular L-ergothioneine level A cell phenotype in which the amount of L-ergothioneine measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0003864 biolink:NamedThing decreased level of substance in cell during G0 A cell phenotype in which the amount a specific substance measured in a cell is lower than normal when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0004141 biolink:NamedThing decreased cellular glutathione level during nitrogen starvation A cell phenotype in which the amount of glutathione (GSH) measured in a cell that is subject to nitrogen starvation is lower than normal. FYPO_relaxed.owl FYPO:0004900 biolink:NamedThing decreased cellular thiamine level during stationary phase A cell phenotype in which the amount of thiamine measured in a cell is lower than normal when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0006673 biolink:NamedThing decreased DNA content in spore A cell phenotype in which the total amount of DNA in a spore is lower than normal. FYPO_relaxed.owl FYPO:0007342 biolink:NamedThing decreased triglyceride level in lipid droplet A cell phenotype in which the amount of one or more triglycerides measured in lipid droplets is lower than normal. FYPO_relaxed.owl FYPO:0007602 biolink:NamedThing decreased cellular superoxide level during nitrogen starvation A cell phenotype in which the amount of superoxide measured in a cell that is subject to nitrogen starvation is lower than normal. FYPO_relaxed.owl FYPO:0008145 biolink:NamedThing decreased level of heme O in cell A cell phenotype in which the amount of heme O measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0000832 biolink:NamedThing elongated nucleus during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is longer than normal. FYPO_relaxed.owl FYPO:0004115 biolink:NamedThing inviable after spore germination, without cell division, abnormal septum morphology, enlarged nucleus A phenotype in which a spore germinates to produce an inviable cell that does not divide, and that has a septum with abnormal size, shape, or structure and a nucleus that is larger than normal. FYPO_relaxed.owl FYPO:0006664 biolink:NamedThing elongated nucleus during G0 A cell phenotype observed during G0 phase in which the nucleus is longer than normal. FYPO_relaxed.owl FYPO:0000833 biolink:NamedThing normal protein level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001077 biolink:NamedThing normal polysaccharide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001153 biolink:NamedThing normal cellular methylamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of methylamine measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001199 biolink:NamedThing normal cellular calcium level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001317 biolink:NamedThing normal RNA level during vegetative growth A cell phenotype in which the amount of RNA measured in a cell is normal (i.e. indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0001410 biolink:NamedThing normal cellular sulfide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-, also called acid labile sulfide) measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001449 biolink:NamedThing normal cellular trehalose level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001506 biolink:NamedThing normal cellular phosphatidylcholine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylcholine measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001535 biolink:NamedThing normal cellular zinc level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001536 biolink:NamedThing normal cellular copper level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of copper ion measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001537 biolink:NamedThing normal cellular iron level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of iron ion measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001538 biolink:NamedThing normal cellular potassium level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of potassium ion measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001539 biolink:NamedThing normal cellular magnesium level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of magnesium ion measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001540 biolink:NamedThing normal cellular manganese level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of manganese ion measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001541 biolink:NamedThing normal cellular molybdenum level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of molybdenum ion measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001542 biolink:NamedThing normal cellular nickel level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nickel ion measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001543 biolink:NamedThing normal cellular phosphorus level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phosphorus-containing substance measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001544 biolink:NamedThing normal cellular sulfur level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfur measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001603 biolink:NamedThing normal level of substance in vacuole A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001606 biolink:NamedThing normal level of substance in cytosol A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cytosol is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001635 biolink:NamedThing normal cellular serine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-serine measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001636 biolink:NamedThing normal cellular glutamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001637 biolink:NamedThing normal cellular glycine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glycine measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001638 biolink:NamedThing normal cellular alanine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-alanine measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001640 biolink:NamedThing normal cellular leucine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-leucine measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001641 biolink:NamedThing normal cellular tyrosine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tyrosine measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001642 biolink:NamedThing normal cellular phenylalanine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-phenylalanine measured in the cell is normal (i.e. indistinguishable from wild type). 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Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. 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Need818a0f5d849239b089854685126f2 biolink:NamedThing FYPO_relaxed.owl N4565d0f8799e488e83cd96a422d0abea biolink:NamedThing FYPO_relaxed.owl N584b9cb03eef4c29b677a2313e1c23da biolink:NamedThing FYPO_relaxed.owl Na3682ca86b6e4cc18337df247344ca47 biolink:NamedThing FYPO_relaxed.owl Nac2e84137be54332b7bb5605007ce60e biolink:NamedThing FYPO_relaxed.owl N901e7ec19c314b4f8e0a377adf8b9b54 biolink:NamedThing FYPO_relaxed.owl FYPO:0001643 biolink:NamedThing normal cellular tryptophan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of tryptophan measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001725 biolink:NamedThing normal cellular aspartate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-aspartate measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002229 biolink:NamedThing normal cellular ergosterol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ergosterol measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002236 biolink:NamedThing normal cellular sterol ester level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more sterol esters measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002316 biolink:NamedThing normal cellular squalene level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of squalene measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002745 biolink:NamedThing normal cellular proline level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-proline measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002746 biolink:NamedThing normal cellular valine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-valine measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002747 biolink:NamedThing normal cellular lysine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-lysine measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003118 biolink:NamedThing normal cellular reactive oxygen species level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of reactive oxygen species (ROS) measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003374 biolink:NamedThing normal cellular coenzyme Q10 level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of coenzyme Q10 measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003774 biolink:NamedThing normal level of transposon-derived cDNA in cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cDNA derived from transposon-encoded genes measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003794 biolink:NamedThing normal cellular glycerol level during cellular response to osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell is normal (i.e. indistinguishable from wild type) during a cellular response to osmotic stress. FYPO_relaxed.owl FYPO:0003795 biolink:NamedThing normal cell wall alpha-glucan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in the cell wall is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004012 biolink:NamedThing normal cell surface pyruvylated galactose level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 4,6-pyruvylated D-galactose (4,6-O-[(1R)-1-carboxyethylidene]-D-galactose) measured at the cell surface is normal (i.e. indistinguishable from wild type). The cell surface refers to the external part of the cell wall and/or plasma membrane. FYPO_relaxed.owl FYPO:0004533 biolink:NamedThing normal cell wall beta-glucan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in the cell wall is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004861 biolink:NamedThing normal cell wall galactomannan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in the cell wall is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004947 biolink:NamedThing normal mitochondrial membrane cardiolipin level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cardiolipin measured in membranes that form the mitochondrial envelope is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004959 biolink:NamedThing normal level of substance in mitochondrion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the mitochondrion is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005595 biolink:NamedThing normal cellular ceramide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a ceramide measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006627 biolink:NamedThing normal phosphatidylinositol-4,5-bisphosphate level in plasma membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4,5-bisphosphate measured in the plasma membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006629 biolink:NamedThing normal phosphatidylinositol-4-phosphate level in plasma membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in the plasma membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006632 biolink:NamedThing normal cellular free fatty acid level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more free fatty acids measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006934 biolink:NamedThing normal cellular triglyceride level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more triglycerides measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008266 biolink:NamedThing normal cellular phosphate (Pi) level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphate (Pi) in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008284 biolink:NamedThing normal cellular myo-inositol level A cell phenotype in which the amount of myo-inositol in a cell is normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0004083 biolink:NamedThing normal protein level A cell phenotype in which the amount of protein measured in a cell is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004084 biolink:NamedThing normal protein level during nitrogen starvation A cell phenotype in which the amount of protein measured in a cell that is subject to nitrogen starvation is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004606 biolink:NamedThing normal protein level during meiotic cell cycle A cell phenotype in which the amount of protein measured in a cell during the meiotic cell cycle is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004634 biolink:NamedThing normal protein level during meiosis A cell phenotype in which the amount of protein measured in a cell during one or both meiotic nuclear divisions is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0006573 biolink:NamedThing normal protein level during cellular response to pheromone A cell phenotype in which the amount of protein measured in a cell during a cellular response to a pheromone is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0006948 biolink:NamedThing normal protein level during glucose starvation A cell phenotype in which the amount of protein measured in a cell that is subject to glucose starvation is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007952 biolink:NamedThing normal protein level during stationary phase A cell phenotype in which the amount of protein measured in a cell is normal (i.e. indistinguishable from wild type), during stationary phase. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0000836 biolink:NamedThing increased protein level A cell phenotype in which the amount of protein measured in a cell is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001325 biolink:NamedThing altered protein level during vegetative growth A cell phenotype in which the amount of protein measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0002685 biolink:NamedThing increased cellular trehalose level A cell phenotype in which the amount of trehalose measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002949 biolink:NamedThing increased level of substance in cell during G0 A cell phenotype in which the amount a specific substance measured in a cell is higher than normal when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0003004 biolink:NamedThing increased cellular reactive oxygen species level during vegetative growth A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0003522 biolink:NamedThing increased cellular hercynylcysteine sulfoxide level A cell phenotype in which the amount of hercynylcysteine sulfoxide measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003523 biolink:NamedThing increased cellular hercynylselenocysteine level A cell phenotype in which the amount of hercynylselenocysteine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0004140 biolink:NamedThing increased cellular glutathione level during nitrogen starvation A cell phenotype in which the amount of glutathione (GSH) measured in a cell that is subject to nitrogen starvation is higher than normal. FYPO_relaxed.owl FYPO:0006381 biolink:NamedThing increased cellular reactive oxygen species level during nitrogen starvation A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0005135 biolink:NamedThing normal protein localization to linear element A cell phenotype in which the localization of a protein to linear elements is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005612 biolink:NamedThing normal protein localization to nuclear envelope A cell phenotype in which the localization of a protein to the nuclear envelope is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006554 biolink:NamedThing normal protein localization to nucleus during nitrogen starvation A cell phenotype in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0002024 biolink:NamedThing inviable elongated multinucleate aseptate vegetative cell A cell morphology phenotype in which a vegetative cell is inviable, is elongated, has no septum, and contains more than one nucleus. FYPO_relaxed.owl FYPO:0003763 biolink:NamedThing inviable aseptate mononucleate vegetative cell A cell phenotype in which a cell is inviable and contains one nucleus and no septum. FYPO_relaxed.owl FYPO:0003501 biolink:NamedThing inviable aseptate mononucleate vegetative cell, normal cell length A cell phenotype in which a cell is inviable, is normal length, and contains one nucleus and no septum. FYPO_relaxed.owl FYPO:0003764 biolink:NamedThing inviable after spore germination, single or double cell division, arrest with aseptate mononucleate cell A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and all cells produced arrest the cell cycle with one nucleus and no septum, and then die. FYPO_relaxed.owl FYPO:0005367 biolink:NamedThing inviable mononucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition A cell morphology phenotype in which a vegetative cell is inviable, contains one nucleus, has no septum, and progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition. FYPO_relaxed.owl FYPO:0001917 biolink:NamedThing inviable elongated mononucleate monoseptate vegetative cell A cell phenotype in which a cell is inviable, contains a single septum, has one nucleus in the septated cell, and is elongated. FYPO_relaxed.owl FYPO:0002337 biolink:NamedThing inviable elongated mononucleate vegetative cell with mislocalized nucleus A cell phenotype in which a cell has one nucleus that is not in the normal location, is elongated, and is inviable. FYPO_relaxed.owl FYPO:0004626 biolink:NamedThing inviable curved elongated mononucleate vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, is curved along the long axis, and contains one nucleus. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0007701 biolink:NamedThing inviable elongated mononucleate cell with cell cycle arrest at mitotic G2/M phase transition A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is longer than normal, has one nucleus, and the mitotic cell cycle is arrested with nuclei at the mitotic G2/M phase transition. FYPO_relaxed.owl FYPO:0008033 biolink:NamedThing elongated mononucleate aseptate cell with cell cycle arrest in mitotic S-phase A cell morphology phenotype in which a vegetative cell is elongated, has no septum, and contains one nucleus, and is arrested in mototic S-phase FYPO_relaxed.owl FYPO:0000840 biolink:NamedThing normal RNA level A cell phenotype in which the amount of RNA measured in a cell is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0001383 biolink:NamedThing normal DNA content A cell phenotype in which the amount of DNA measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001666 biolink:NamedThing normal cAMP level A cell phenotype in which the amount of cyclic AMP measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004133 biolink:NamedThing normal reactive oxygen species level during nitrogen starvation A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell that is subject to nitrogen starvation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008005 biolink:NamedThing normal reactive oxygen species level during stationary phase A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell that is normal (i.e. indistinguishable from wild type) during stationary phase. FYPO_relaxed.owl FYPO:0008134 biolink:NamedThing normal cellular polyphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyphosphate measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008237 biolink:NamedThing normal glycerophospholipid level during vegetative growth A cell phenotype in which the amount of glycerophospholipid measured in a cell is normal (i.e. indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0002276 biolink:NamedThing increased protein degradation A cellular process phenotype in which the occurrence of protein degradation is increased. FYPO_relaxed.owl FYPO:0002796 biolink:NamedThing abnormal protein degradation during nitrogen starvation A cellular process phenotype in which protein degradation is abnormal when the cell is subject to nitrogen starvation. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0002797 biolink:NamedThing decreased protein degradation A cellular process phenotype in which the occurrence of protein degradation is decreased. FYPO_relaxed.owl FYPO:0006531 biolink:NamedThing delayed onset of protein degradation during meiosis A cellular process phenotype which protein degradation begins later than normal during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0002798 biolink:NamedThing decreased protein degradation during nitrogen starvation A cellular process phenotype in which the occurrence of protein degradation is decreased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0004930 biolink:NamedThing decreased protein degradation during sporulation A cellular process phenotype in which the occurrence of protein degradation is decreased during sporulation. FYPO_relaxed.owl FYPO:0002277 biolink:NamedThing increased protein degradation during nitrogen starvation A cellular process phenotype in which the occurrence of protein degradation is increased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006768 biolink:NamedThing increased protein degradation in absence of meiotic DNA replication checkpoint arrest A cellular process phenotype in which the occurrence of protein degradation is increased during the meiotic cell cycle, in cells that have not arrested the meiotic cell cycle under conditions that normally trigger meiotic DNA replication checkpoint signaling and response. FYPO_relaxed.owl FYPO:0005601 biolink:NamedThing abnormal chromosome morphology during meiotic cell cycle A physical cellular phenotype in which the size, shape, or structure of one or more chromosomes is abnormal during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0002045 biolink:NamedThing resistance to heat shock A cell phenotype in which cells show decreased sensitivity to heat shock. Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature. FYPO_relaxed.owl FYPO:0009010 biolink:NamedThing resistance to UV during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased resistance to ultraviolet light. FYPO_relaxed.owl FYPO:0000851 biolink:NamedThing resistance to osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to osmotic stress. FYPO_relaxed.owl FYPO:0001090 biolink:NamedThing resistance to heat shock during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to heat shock. Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature. FYPO_relaxed.owl FYPO:0001450 biolink:NamedThing resistance to cold A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to cold. FYPO_relaxed.owl FYPO:0001452 biolink:NamedThing resistance to water deprivation A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to water deprivation. FYPO_relaxed.owl FYPO:0002312 biolink:NamedThing resistance to ionizing radiation during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to ionizing radiation. FYPO_relaxed.owl FYPO:0002626 biolink:NamedThing resistance to heat A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to heat. FYPO_relaxed.owl FYPO:0003376 biolink:NamedThing resistance to nitrogen starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to nitrogen starvation. Cells go on to grow and divide to a greater extent than wild type following nitrogen starvation. FYPO_relaxed.owl FYPO:0007161 biolink:NamedThing resistance to oxidative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to oxidative stress. FYPO_relaxed.owl FYPO:0000852 biolink:NamedThing resistance to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to a salt stress. FYPO_relaxed.owl FYPO:0000853 biolink:NamedThing abnormal nucleosome positioning A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning is abnormal. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another. FYPO_relaxed.owl FYPO:0004308 biolink:NamedThing abnormal CENP-A containing chromatin organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which CENP-A-containing chromatin organization is abnormal. FYPO_relaxed.owl FYPO:0004505 biolink:NamedThing abnormal nucleolar chromatin organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleolar chromatin organization is abnormal. FYPO_relaxed.owl FYPO:0004543 biolink:NamedThing abnormal heterochromatin organization during vegetative growth A cellular process phenotype in which any process of heterochromatin organization is abnormal in the vegetative growth phase of the life cycle. Heterochromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin. FYPO_relaxed.owl FYPO:0005350 biolink:NamedThing abnormal chromatin organization resulting in peripheral chromatin distribution A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear chromatin organization is abnormal, such that chromatin is distributed in a ring-shaped structure around the nuclear periphery rather than throughout the nucleus. FYPO_relaxed.owl FYPO:0005521 biolink:NamedThing abnormal nucleosome organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome organization is abnormal. Nucleosome organization results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes. FYPO_relaxed.owl FYPO:0005545 biolink:NamedThing decreased Tf body formation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear chromatin organization is abnormal, such that regions containing transposons (Tf2 elements) are physically clustered to a lower extent than normal. FYPO_relaxed.owl FYPO:0006359 biolink:NamedThing decreased protein exchange at pericentric heterochromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of a protein in cis and trans between heterochromatin domains occurs to a lower extent than normal in regions of pericentric heterochromatin. FYPO_relaxed.owl FYPO:0007160 biolink:NamedThing abnormal DNA replication-dependent nucleosome assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the formation of nucleosomes on newly replicated DNA is abnormal. FYPO_relaxed.owl FYPO:0007270 biolink:NamedThing decreased Tf body tethering to centromere A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear chromatin organization is abnormal, such regions containing transposons (Tf2 elements) are tethered to the centromere to a lower extent than normal. FYPO_relaxed.owl FYPO:0007271 biolink:NamedThing increased Tf body tethering to centromere A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear chromatin organization is abnormal, such regions containing transposons (Tf2 elements) are tethered to the centromere to a greater extent than normal. FYPO_relaxed.owl FYPO:0007517 biolink:NamedThing increased chromatin mobility A cell phenotype observed in the vegetative growth phase of the life cycle in which chromatin moves within the nucleus to a greater extent than normal. FYPO_relaxed.owl FYPO:0007628 biolink:NamedThing abnormal chromatin organization during mitotic G2 phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear chromatin organization is abnormal during G2 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007637 biolink:NamedThing decreased chromatin mobility A cell phenotype observed in the vegetative growth phase of the life cycle in which chromatin moves within the nucleus to a lower extent than normal. FYPO_relaxed.owl FYPO:0000854 biolink:NamedThing abnormal nucleosome positioning in euchromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of euchromatin is abnormal. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another. FYPO_relaxed.owl FYPO:0000855 biolink:NamedThing abnormal nucleosome positioning in heterochromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of heterochromatin is abnormal. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another. FYPO_relaxed.owl FYPO:0004491 biolink:NamedThing decreased nucleosome occupancy A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at one or more specific sites. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0007655 biolink:NamedThing increased nucleosome occupancy A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is higher than normal at one or more specific sites. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0000857 biolink:NamedThing normal nucleosome positioning in euchromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of euchromatin is normal (i.e. indistinguishable from wild type). Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another. FYPO_relaxed.owl FYPO:0000858 biolink:NamedThing normal nucleosome positioning in heterochromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in regions of heterochromatin is normal (i.e. indistinguishable from wild type). Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another. FYPO_relaxed.owl FYPO:0005920 biolink:NamedThing normal nucleosome occupancy at tRNA genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is normal (i.e. indistinguishable from wild type) at tRNA genes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0007843 biolink:NamedThing normal nucleosome positioning at centromere A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning in centromeric regions is normal (i.e. indistinguishable from wild type). Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another. FYPO_relaxed.owl FYPO:0000861 biolink:NamedThing normal histone methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone methylation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002595 biolink:NamedThing normal histone phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone phosphorylation is normal. All histone phosphorylation may be assayed, or phosphorylation of specific sites on specific histones may be measured. FYPO_relaxed.owl FYPO:0002923 biolink:NamedThing normal histone H2B-K119 ubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B is normal (i.e. indistinguishable from wild type). Lysine 119 corresponds to the conserved C-terminal lysine of H2B. FYPO_relaxed.owl FYPO:0003221 biolink:NamedThing normal histone acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone acetylation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005340 biolink:NamedThing normal histone H4 deacetylation during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which deacetylation of lysine at position 4 of histone H4 is normal (i.e. indistinguishable from wild type) during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0000862 biolink:NamedThing normal histone H3-K9 dimethylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromeric regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008070 biolink:NamedThing normal histone H3-K9 methylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 9 of histone H3 in centromeric regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003235 biolink:NamedThing normal histone H3-K9 methylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at centromere outer repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006683 biolink:NamedThing normal histone H3-K9 methylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at centromere inner repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008072 biolink:NamedThing normal spatial extent of histone H3-K9 methylation at peri-centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs over the same portion of the peri-centromere as normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008186 biolink:NamedThing normal histone H3-K9 trimethylation at centromere central core during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 at the centromere central core is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000863 biolink:NamedThing normal histone H3-K9 dimethylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008203 biolink:NamedThing normal histone H3-K9 trimethylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 at the centromere inner repeat region is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000864 biolink:NamedThing abnormal histone H3-K9 trimethylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromeric regions is abnormal. FYPO_relaxed.owl FYPO:0000879 biolink:NamedThing increased histone H3-K9 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000882 biolink:NamedThing decreased histone H3-K9 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004577 biolink:NamedThing decreased histone H3-K9 trimethylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 in subtelomeric regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005844 biolink:NamedThing abolished histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes does not occur. FYPO_relaxed.owl FYPO:0005845 biolink:NamedThing decreased histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0000867 biolink:NamedThing abnormal histone H3-K9 dimethylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromeric regions is abnormal. FYPO_relaxed.owl FYPO:0007337 biolink:NamedThing increased histone H3-K4 methylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 4 of histone H3 in centromeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000865 biolink:NamedThing abnormal histone H3-K9 trimethylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions is abnormal. FYPO_relaxed.owl FYPO:0000881 biolink:NamedThing increased histone H3-K9 trimethylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000883 biolink:NamedThing decreased histone H3-K9 trimethylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromeric regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0000885 biolink:NamedThing abnormal histone H3-K9 trimethylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions is abnormal. FYPO_relaxed.owl FYPO:0000889 biolink:NamedThing increased histone H3-K9 trimethylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000873 biolink:NamedThing increased histone H3-K9 dimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000876 biolink:NamedThing decreased histone H3-K9 dimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0000868 biolink:NamedThing abnormal histone H3-K9 dimethylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions is abnormal. FYPO_relaxed.owl FYPO:0000877 biolink:NamedThing decreased histone H3-K9 dimethylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromeric regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0000886 biolink:NamedThing abnormal histone H3-K9 dimethylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions is abnormal. FYPO_relaxed.owl FYPO:0004223 biolink:NamedThing increased histone H4-K20 monomethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which monomethylation of lysine at position 20 of histone H4 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005225 biolink:NamedThing increased histone H3-K4 dimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 4 of histone H3 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0002366 biolink:NamedThing decreased histone H3-K4 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 4 of histone H3 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0003231 biolink:NamedThing decreased histone H3-K9 methylation at heterochromatin domain during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at heterochromatin domains occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004224 biolink:NamedThing decreased histone H4-K20 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 20 of histone H4 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005028 biolink:NamedThing decreased H4-K20 dimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 20 of histone H4 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0003102 biolink:NamedThing increased histone H3-K9 methylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in regions containing protein-coding genes occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0003746 biolink:NamedThing increased histone H3-K9 methylation at heterochromatin island during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in heterochromatin islands occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005064 biolink:NamedThing increased histone H3-K9 methylation at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in telomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005065 biolink:NamedThing increased histone H3-K9 methylation at mating type locus during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at the mating type locus occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000874 biolink:NamedThing increased histone H3-K9 dimethylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0004138 biolink:NamedThing increased histone H3-K9 dimethylation at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in telomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006074 biolink:NamedThing increased histone H3-K9 dimethylation at rDNA during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal at ribosomal DNA. FYPO_relaxed.owl FYPO:0006268 biolink:NamedThing increased histone H3-K9 dimethylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in regions containing protein-coding genes occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006361 biolink:NamedThing increased histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in heterochromatin at subtelomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006369 biolink:NamedThing increased histone H3-K9 dimethylation at heterochromatin domain during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in one or more heterochromatin domains occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006373 biolink:NamedThing increased histone H3-K9 dimethylation at heterochromatin island during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in one or more heterochromatin islands occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006987 biolink:NamedThing increased histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006988 biolink:NamedThing increased histone H3-K9 dimethylation at transposable element during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal at transposable elements. FYPO_relaxed.owl FYPO:0000880 biolink:NamedThing increased histone H3-K9 trimethylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005169 biolink:NamedThing increased histone H3-K9 methylation at centromere central core during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at the centromere central core occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007844 biolink:NamedThing increased histone H3-K9 monomethylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the monomethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000875 biolink:NamedThing increased histone H3-K9 dimethylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000878 biolink:NamedThing decreased histone H3-K9 dimethylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0000887 biolink:NamedThing increased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0003230 biolink:NamedThing decreased histone H3-K9 methylation at heterochromatin island during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at heterochromatin islands occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0003571 biolink:NamedThing decreased histone H3-K9 methylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in heterochromatin at the silenced mating-type cassettes occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0003572 biolink:NamedThing decreased histone H3-K9 methylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in heterochromatin at subtelomeric regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0008200 biolink:NamedThing decreased histone H3-K9 methylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs to a lower extent than normal at the centromere inner repeat. FYPO_relaxed.owl FYPO:0002355 biolink:NamedThing decreased histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004137 biolink:NamedThing decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in heterochromatin at subtelomeric regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005867 biolink:NamedThing decreased histone H3-K9 dimethylation at rDNA during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 at ribosomal DNA occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006269 biolink:NamedThing decreased histone H3-K9 dimethylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in regions containing protein-coding genes occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007213 biolink:NamedThing decreased histone H3-K9 dimethylation at heterochromatin island during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in one or more heterochromatin islands occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0000888 biolink:NamedThing decreased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0000884 biolink:NamedThing decreased histone H3-K9 trimethylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007507 biolink:NamedThing increased histone H3-K9 trimethylation at promoter during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in one or more promoter regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007508 biolink:NamedThing increased histone H3-K9 trimethylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 at subtelomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007509 biolink:NamedThing increased histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007653 biolink:NamedThing decreased histone H3-K9 trimethylation at heterochromatin island at meiotic gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 is decreased at heterochromatin islands near genes that are normally expressed during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0000890 biolink:NamedThing decreased histone H3-K9 trimethylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0008185 biolink:NamedThing decreased histone H3-K9 trimethylation at centromere central core during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in the centromere central core occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0000892 biolink:NamedThing increased histone H3-K9 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0002370 biolink:NamedThing increased histone H3-K56 acetylation in transcribed regions during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 56 of histone H3 in regions of the genome that are actively transcribed occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0002381 biolink:NamedThing increased histone H3 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3 acetylation occurs to a greater extent than normal in centromere outer repeat regions. FYPO_relaxed.owl FYPO:0003745 biolink:NamedThing increased histone H3 acetylation at centromere central core during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3 acetylation occurs to a greater extent than normal in the central core of the centromeric regions. FYPO_relaxed.owl FYPO:0004238 biolink:NamedThing increased histone H3-K4 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 4 of histone H3 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005310 biolink:NamedThing increased histone H3-K14 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000893 biolink:NamedThing increased histone H3-K9 acetylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in centromeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0002819 biolink:NamedThing increased histone H3-K9 acetylation at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in telomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0004347 biolink:NamedThing increased histone H3-K9 acetylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 occurs to a greater extent than normal in regions containing protein-coding genes. FYPO_relaxed.owl FYPO:0004575 biolink:NamedThing increased histone H3-K9 acetylation at subtelomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in subtelomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0004690 biolink:NamedThing increased histone H3-K9 acetylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 at the silent mating-type cassettes occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006681 biolink:NamedThing increased histone H3-K9 acetylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007630 biolink:NamedThing increased histone H3-K9 acetylation at rDNA during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 9 of histone H3 at ribosomal DNA occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007636 biolink:NamedThing increased histone H3-K9 acetylation at promoter during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 9 of histone H3 at in one or more promoter regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000894 biolink:NamedThing abnormal intracellular mitochondrion distribution A cellular process phenotype observed in the vegetative growth phase of the life cycle in which intracellular mitochondrion distribution, the process that results in the spatial arrangement of mitochondria in a cell, is abnormal. FYPO_relaxed.owl FYPO:0000906 biolink:NamedThing abnormal mitochondrion inheritance during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrion inheritance is abnormal. Mitochondrion inheritance is a cellular process that results in the distribution of mitochondria into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton. FYPO_relaxed.owl FYPO:0000895 biolink:NamedThing mitochondrial aggregation An abnormal intracellular mitochondrion distribution phenotype observed in the vegetative growth phase of the life cycle in which mitochondria cluster together more than normal with a cluster distal to one or both sides of the nucleus. FYPO_relaxed.owl FYPO:0009002 biolink:NamedThing increased mitochondrial-associated microtubule fraction during mitotic interphase A mitochondrion distribution phenotype observed during mitotic interphase in which the length fraction of cytoplasmic microtubules that is bound to mitochondria is increased with respect to the wild type. FYPO_relaxed.owl FYPO:0003052 biolink:NamedThing abnormal homologous chromosome pairing at cis-acting homologous chromosome pairing region A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is abnormal at a cis-acting homologous chromosome pairing region such as the sme2 locus. FYPO_relaxed.owl FYPO:0003053 biolink:NamedThing increased homologous chromosome pairing at cis-acting homologous chromosome pairing region A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is increased (i.e. occurs to a greater extent) at a cis-acting homologous chromosome pairing region such as the sme2 locus. FYPO_relaxed.owl FYPO:0003055 biolink:NamedThing delayed onset of homologous chromosome pairing at cis-acting homologous chromosome pairing region A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is delayed at a cis-acting homologous chromosome pairing region such as the sme2 locus. FYPO_relaxed.owl FYPO:0003539 biolink:NamedThing decreased global homologous chromosome pairing A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased (i.e. occurs to a lower extent) over the entire length of the chromosomes. FYPO_relaxed.owl FYPO:0003540 biolink:NamedThing decreased regional homologous chromosome pairing A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased (i.e. occurs to a lower extent) in one or more specific regions of the chromosomes. FYPO_relaxed.owl FYPO:0007977 biolink:NamedThing abnormal homologous chromosome pairing during meiosis I prophase A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is abnormal during meiotic prophase I. FYPO_relaxed.owl FYPO:0007956 biolink:NamedThing abnormal duration of microtubule growth event A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which the duration of microtubule growth events is abnormal. FYPO_relaxed.owl FYPO:0007957 biolink:NamedThing abnormal microtubule rescue A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule rescue (the transition from shrinkage to growth) is abnormal. The frequency of rescues as well as the organisation can be affected. FYPO_relaxed.owl FYPO:0008006 biolink:NamedThing dynamic microtubule minus ends in interphase bundles A microtubule cytoskeleton phenotype observed during mitotic interphase in which the microtubule minus ends are dynamic (they alternate between growth and shrinkage phases). FYPO_relaxed.owl FYPO:0007112 biolink:NamedThing decreased rate of microtubule depolymerization involved in meiotic centromere clustering during meiotic prophase I A cellular process in which depolymerization (i.e. removal of tubulin dimers) of microtubules occurs at a lower rate, or speed, as part of centromere clustering during meiotic prophase I. FYPO_relaxed.owl FYPO:0000903 biolink:NamedThing decreased rate of microtubule depolymerization during vegetative growth A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, occurs at a lower rate, or speed, than normal. FYPO_relaxed.owl FYPO:0007954 biolink:NamedThing abnormal rate of microtubule depolymerization during vegetative growth A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which the rate or speed of microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, is abnormal. FYPO_relaxed.owl FYPO:0003194 biolink:NamedThing increased rate of microtubule depolymerization during vegetative growth A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule, occurs at a greater rate, or speed, than normal. FYPO_relaxed.owl FYPO:0007946 biolink:NamedThing decreased protein ubiquitination A cellular process phenotype in which the occurrence of ubiquitination of one or more specific proteins, or of specific protein sites, is decreased. FYPO_relaxed.owl FYPO:0007275 biolink:NamedThing abnormal mitochondrion inheritance during meiotic cell cycle A cellular process phenotype in which mitochondrion inheritance is abnormal during the meiotic cell cycle. Mitochondrion inheritance is a cellular process that results in the distribution of mitochondria into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton. FYPO_relaxed.owl FYPO:0000909 biolink:NamedThing abnormal protein localization to linear element A cell phenotype in which the localization of a protein to linear elements is abnormal. FYPO_relaxed.owl FYPO:0002957 biolink:NamedThing abnormal protein localization to nucleus during meiosis A cell phenotype in which the localization of a protein to the nucleus is abnormal during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0004455 biolink:NamedThing decreased protein localization to nucleus A cell phenotype in which the localization of a protein to the nucleus is decreased. FYPO_relaxed.owl FYPO:0004456 biolink:NamedThing increased protein localization to nucleus A cell phenotype in which the localization of a protein to the nucleus is increased. FYPO_relaxed.owl FYPO:0005667 biolink:NamedThing premature protein localization to nucleus during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus begins earlier than normal. FYPO_relaxed.owl FYPO:0006183 biolink:NamedThing abnormal protein localization to nucleus during meiotic prophase I A cell phenotype in which the localization of a protein to the nucleus is abnormal during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0003549 biolink:NamedThing abnormal protein localization during meiosis A cell phenotype that affects the localization of a protein in a cell during one or both meiotic nuclear divisions. A protein may be observed in a place where it is not normally found, absent from a place where it is normally found, or both. FYPO_relaxed.owl FYPO:0004443 biolink:NamedThing decreased protein localization to prospore membrane during meiosis II A cell phenotype in which the localization of a protein to the prospore membrane is decreased during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0004444 biolink:NamedThing decreased protein localization to prospore membrane during meiosis II with protein mislocalized to plasma membrane A cell phenotype in which the localization of a protein to the prospore membrane is decreased, and the protein is instead present in the plasma membrane, during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0004445 biolink:NamedThing abolished protein localization to prospore membrane during meiosis II with protein mislocalized to plasma membrane A cell phenotype in which the localization of a protein to the prospore membrane does not occur, and the protein is instead present in the plasma membrane, during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0004717 biolink:NamedThing abnormal protein localization to heterochromatin during meiosis A cell phenotype in which the localization of a protein to heterochromatin is abnormal during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0004762 biolink:NamedThing abnormal protein localization to kinetochore during meiosis A cell phenotype in which the localization of a protein to the kinetochore is abnormal during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0006454 biolink:NamedThing abnormal protein localization to meiotic spindle A cell phenotype in which the localization of a protein to the meiotic spindle is abnormal. FYPO_relaxed.owl FYPO:0006868 biolink:NamedThing decreased protein localization to cell cortex during meiotic prophase I A cell phenotype in which the localization of a protein to the cell cortex is decreased during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0008190 biolink:NamedThing increased protein localization to chromatin at centromere central core during meiotic prophase I A cell phenotype in which the localization of a protein to chromatin at the centromere central core is increased during the meiotic prophase I. FYPO_relaxed.owl FYPO:0004888 biolink:NamedThing abnormal protein localization to telomere A cell phenotype in which the localization of a protein to the telomere of a chromosome is abnormal. FYPO_relaxed.owl FYPO:0000911 biolink:NamedThing increased nuclear RNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in the cell nucleus is higher than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0001242 biolink:NamedThing increased RNA level during cellular response to adenine starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to adenine starvation is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001243 biolink:NamedThing increased RNA level during cellular response to thiamine A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to thiamine is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001279 biolink:NamedThing increased RNA level during cellular response to oxidative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to oxidative stress is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001456 biolink:NamedThing increased RNA level during cellular response to endoplasmic reticulum stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to endoplasmic reticulum stress is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001547 biolink:NamedThing increased RNA level during cellular response to zinc ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to zinc ion starvation is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001573 biolink:NamedThing increased RNA level during cellular response to rapamycin A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to rapamycin is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001685 biolink:NamedThing increased RNA level during cellular response to purvalanol A A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to purvalanol A is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001908 biolink:NamedThing increased pre-mRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any unspliced or incompletely spliced mRNA precursor measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001979 biolink:NamedThing increased lariat intron level A cell phenotype observed in the vegetative growth phase of the life cycle in which excised introns in lariat form (i.e. not linearized) are present at greater levels than normal. FYPO_relaxed.owl FYPO:0002014 biolink:NamedThing increased RNA level during cellular response to iron ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to iron ion starvation is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002172 biolink:NamedThing increased level of nitrogen starvation gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during nitrogen starvation measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). FYPO_relaxed.owl FYPO:0002173 biolink:NamedThing increased level of meiotic gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during the meiotic cell cycle measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). FYPO_relaxed.owl FYPO:0002587 biolink:NamedThing increased level of mitochondrial polycistronic RNA precursors A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any mitochondrially-encoded polycistronic RNA precursors measured in the cell is higher than normal. FYPO_relaxed.owl FYPO:0002664 biolink:NamedThing increased level of stress responsive gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more messenger RNAs that are normally expressed during a cellular response to stress measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). FYPO_relaxed.owl FYPO:0002743 biolink:NamedThing increased level of amino acid metabolism gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more amino acid metabolism RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Amino acid metabolism RNAs are transcribed from genes whose products are involved in metabolism of one or more amino acids. FYPO_relaxed.owl FYPO:0002985 biolink:NamedThing increased RNA level during cellular response to methyl methanesulfonate A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to methyl methanesulfonate is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003104 biolink:NamedThing increased mRNA-derived small RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from mRNA transcripts measured in a cell is greater than normal. FYPO_relaxed.owl FYPO:0003119 biolink:NamedThing increased nuclear polyadenylated mRNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyadenylated messenger RNA (mRNA) measured in the nucleus is higher than normal. Total mRNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0003424 biolink:NamedThing increased mitochondrial RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mitochondrial RNA measured in a cell is greater than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003558 biolink:NamedThing increased repeat element RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any RNA transcribed from repeat elements, such as LTRs, retrotransposons, or wtf elements, measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0004191 biolink:NamedThing increased RNA level during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydroxyurea is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004388 biolink:NamedThing increased level of pyrimidine salvage gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more pyrimidine salvage RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Pyrimidine salvage RNAs are transcribed from genes whose products are involved in pyrimidine salvage. FYPO_relaxed.owl FYPO:0004490 biolink:NamedThing increased level of transport gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more transport RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Transport RNAs are transcribed from genes whose products are involved in one or more transport processes. FYPO_relaxed.owl FYPO:0004647 biolink:NamedThing increased RNA level during cellular response to copper ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to copper ions is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004785 biolink:NamedThing increased RNA level during cellular response to menadione A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to menadione is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004896 biolink:NamedThing increased level of generation of precursor metabolites and energy gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more generation of precursor metabolites and energy RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Generation of precursor metabolites and energy RNAs are transcribed from genes whose products are involved in the formation of precursor metabolites and the liberation of energy from these substances. FYPO_relaxed.owl FYPO:0004934 biolink:NamedThing increased RNA level during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during G1 phase of the mitotic cell cycle is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0005129 biolink:NamedThing increased level of heat shock gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during heat shock measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). FYPO_relaxed.owl FYPO:0005162 biolink:NamedThing increased RNA level during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to salt stress is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0005163 biolink:NamedThing increased RNA level during cellular response to heat A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to heat is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0005279 biolink:NamedThing increased level of glucose-repressed gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more glucose-repressed mRNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Glucose-repressed mRNAs are transcribed from genes whose transcription is negatively regulated when glucose is present. FYPO_relaxed.owl FYPO:0005291 biolink:NamedThing increased RNA level during cellular response to zinc ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to zinc ion is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0005301 biolink:NamedThing increased level of cell cycle regulated gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cell cycle-regulated mRNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Cell cycle-regulated mRNAs are transcribed from genes whose level of transcription varies depending on cell cycle phase. FYPO_relaxed.owl FYPO:0005420 biolink:NamedThing increased level of iron assimilation gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more iron assimilation RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Iron assimilation RNAs are transcribed from genes whose products are involved in any process in which iron is solubilized and transported into a cell. FYPO_relaxed.owl FYPO:0005505 biolink:NamedThing increased level of cell surface glycoprotein gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cell surface glycoprotein mRNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Cell surface glycoprotein gene mRNAs encode proteins that become glycosylated and are transported to the cell surface. FYPO_relaxed.owl FYPO:0006154 biolink:NamedThing increased level of pheromone response gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more pheromone response mRNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Pheromone response genes are normally transcribed in response to a pheromone stimulus. FYPO_relaxed.owl FYPO:0006155 biolink:NamedThing increased level of mating gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more mating mRNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Mating genes are normally transcribed during conjugation with cellular fusion (i.e. mating). FYPO_relaxed.owl FYPO:0006270 biolink:NamedThing increased RNA level during cellular response to phosphate starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to phosphate starvation is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0006413 biolink:NamedThing increased level of histone gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more histone RNAs measured in a cell is higher than normal (i.e. lower than observed in wild-type cells). Histone RNAs are transcribed from genes encoding histones. FYPO_relaxed.owl FYPO:0006542 biolink:NamedThing increased RNA level during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during mitosis is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0006562 biolink:NamedThing increased RNA level during mitotic G2 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during G2 phase of the mitotic cell cycle is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0006596 biolink:NamedThing increased level of flocculin gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs transcribed from genes encoding flocculins measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). FYPO_relaxed.owl FYPO:0006597 biolink:NamedThing increased level of cell wall organization gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cell wall organization RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Cell wall organization RNAs are transcribed from genes whose products are involved in assembly, alteration, or disassembly of the cell wall. FYPO_relaxed.owl FYPO:0006783 biolink:NamedThing increased level of carbohydrate metabolism gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more carbohydrate metabolism RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Carbohydrate metabolism RNAs are transcribed from genes whose products are involved in metabolism of one or more carbohydrates. FYPO_relaxed.owl FYPO:0006849 biolink:NamedThing increased total RNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of RNA measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0007085 biolink:NamedThing increased RNA level during cellular response to sulfur starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to sulfur starvation is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0007093 biolink:NamedThing increased level of ribosomal protein gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs transcribed from genes encoding ribosomal proteins measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). FYPO_relaxed.owl FYPO:0007118 biolink:NamedThing increased RNA level during cellular response to leucine starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to leucine starvation is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0007345 biolink:NamedThing increased euchromatin-derived RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any RNA transcribed from euchromatic regions measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0007407 biolink:NamedThing increased level of phosphate starvation gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during phosphate starvation measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). FYPO_relaxed.owl FYPO:0007464 biolink:NamedThing increased RNA level during cellular response to hypoxia A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hypoxia is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0008146 biolink:NamedThing increased ncRNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of non-coding RNA transcribed measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002033 biolink:NamedThing abolished protein phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur. FYPO_relaxed.owl FYPO:0002507 biolink:NamedThing abolished protein palmitoylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the palmitoylation of one or more specific proteins, or of specific protein sites, does not occur. FYPO_relaxed.owl FYPO:0002592 biolink:NamedThing abolished histone phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone phosphorylation does not occur. All histone phosphorylation may be affected, or phosphorylation of specific sites on specific histones may be abolished. FYPO_relaxed.owl FYPO:0002597 biolink:NamedThing abolished histone H2A phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation does not occur. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be abolished. FYPO_relaxed.owl FYPO:0005676 biolink:NamedThing abolished protein deubiquitination following cellular response to methyl methanesulfonate during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the deubiquitination of one or more specific proteins, or of specific protein sites, does not occur after cells have been exposed to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0005738 biolink:NamedThing abolished histone H3-S10 phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which phosphorylation of serine at position 10 of histone H3 not occur. FYPO_relaxed.owl FYPO:0006283 biolink:NamedThing abolished protein-proline dihydroxylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dihydroxylation of one or more proline residues in specific proteins, or at specific protein sites, does not occur. FYPO_relaxed.owl FYPO:0002082 biolink:NamedThing increased protein ubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of ubiquitination of one or more specific proteins, or of specific protein sites, is increased. FYPO_relaxed.owl FYPO:0002768 biolink:NamedThing decreased protein ubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of ubiquitination of one or more specific proteins, or of specific protein sites, is decreased. FYPO_relaxed.owl FYPO:0000926 biolink:NamedThing normal volume vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal volume. FYPO_relaxed.owl FYPO:0001053 biolink:NamedThing cut, normal size cell An inviable phenotype in which a cell enters mitosis at the same size as wild type, and then septates to give rise to a cut phenotype. In a cut phenotype, a cell undergoes septation despite abnormal mitosis such that the septum physically divides the nucleus into two parts. FYPO_relaxed.owl FYPO:0002176 biolink:NamedThing viable vegetative cell with normal cell size A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has normal volume and dimensions and is viable. FYPO_relaxed.owl FYPO:0003503 biolink:NamedThing normal vegetative cell length A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal length. FYPO_relaxed.owl FYPO:0006639 biolink:NamedThing normal vegetative cell diameter A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has a normal diameter (thickness; width). FYPO_relaxed.owl FYPO:0004605 biolink:NamedThing decreased distance travelled by the spindle pole body during horsetail movement A cellular process phenotype in which the total distance travelled by the SPB during horsetail movement is decreased. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I. PMID:24954111 FYPO_relaxed.owl FYPO:0004966 biolink:NamedThing increased duration of horsetail movement A cellular process phenotype in which the duration of horsetail movement is longer than normal. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I. FYPO_relaxed.owl FYPO:0004998 biolink:NamedThing decreased duration of horsetail movement A cellular process phenotype in which the duration of horsetail movement is shorter than normal. Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I. FYPO_relaxed.owl FYPO:0009004 biolink:NamedThing horsetail movement with unfused nuclei A cellular process phenotype in which horsetail movement occurs without nuclei fusing. This can happen with both nuclei having congressed and their SPBs having coalesced, but nuclei having failed to fuse, see PMID:36650056. FYPO_relaxed.owl FYPO:0002125 biolink:NamedThing abnormal protein localization to plasma membrane during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is abnormal. FYPO_relaxed.owl FYPO:0006536 biolink:NamedThing increased protein localization to cell periphery during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell periphery is increased. FYPO_relaxed.owl FYPO:0006867 biolink:NamedThing abnormal protein localization to cell cortex A cell phenotype in which the localization of a protein to the cell cortex is abnormal. FYPO_relaxed.owl FYPO:0004265 biolink:NamedThing abnormal protein localization to cortical microtubule cytoskeleton A cell phenotype in which the localization of a protein to the cortical microtubule cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0002128 biolink:NamedThing abolished protein localization to plasma membrane, with protein mislocalized to cytoplasm, during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is abolished, and the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0006447 biolink:NamedThing abolished protein localization to cleavage furrow during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cleavage furrow does not occur. FYPO_relaxed.owl FYPO:0006936 biolink:NamedThing abolished protein localization to plasma membrane at cell division site during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell division site is abolished. FYPO_relaxed.owl FYPO:0002769 biolink:NamedThing abnormal protein localization to spindle pole body A cell phenotype in which the localization of a protein to the spindle pole body is abnormal. FYPO_relaxed.owl FYPO:0000932 biolink:NamedThing increased protein localization to microtubule cytoskeleton during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton is increased. FYPO_relaxed.owl FYPO:0000933 biolink:NamedThing decreased protein localization to microtubule cytoskeleton during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the microtubule cytoskeleton is decreased. FYPO_relaxed.owl FYPO:0002824 biolink:NamedThing abnormal protein localization to mitotic spindle A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle is abnormal. FYPO_relaxed.owl FYPO:0003191 biolink:NamedThing abolished protein localization to microtubule during mitotic interphase, with protein mislocalized to cytoplasmic foci A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to microtubules does not occur, and the protein is instead visible in one or a few foci or dots in the cytoplasm, during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004755 biolink:NamedThing abnormal protein localization to microtubule minus-end A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the minus ends of microtubules is abnormal. FYPO_relaxed.owl FYPO:0005702 biolink:NamedThing abnormal protein localization to microtubule organizing center A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more microtubule organizing centers is abnormal. FYPO_relaxed.owl FYPO:0007131 biolink:NamedThing increased protein localization to microtubule plus-end A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plus ends end of microtubules is increased. FYPO_relaxed.owl FYPO:0007998 biolink:NamedThing abnormal protein localization to interphase microtubule bundle A cell phenotype observed during mitotic interphase in which the localization of a protein to interphase microtubule bundles is abnormal. FYPO_relaxed.owl FYPO:0003542 biolink:NamedThing abolished protein localization to meiotic spindle pole body A cell phenotype in which the localization of a protein to the meiotic spindle pole body is abolished. FYPO_relaxed.owl FYPO:0004266 biolink:NamedThing abolished protein localization to cortical microtubule cytoskeleton A cell phenotype in which the localization of a protein to the cortical microtubule cytoskeleton does not occur. FYPO_relaxed.owl FYPO:0006130 biolink:NamedThing abolished protein localization to microtubule during meiosis A cell phenotype in which the localization of a protein to one or more microtubules does not occur during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0006455 biolink:NamedThing abolished protein localization to meiotic spindle during meiosis I A cell phenotype in which the localization of a protein to the meiotic spindle is abolished during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006456 biolink:NamedThing abolished protein localization to meiotic spindle during meiosis II A cell phenotype in which the localization of a protein to the meiotic spindle is abolished during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0000936 biolink:NamedThing increased protein localization to cortical microtubule cytoskeleton during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical microtubule cytoskeleton is increased. FYPO_relaxed.owl FYPO:0002969 biolink:NamedThing increased protein localization to mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is increased. FYPO_relaxed.owl FYPO:0004635 biolink:NamedThing increased protein localization to mitotic spindle A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle is increased. FYPO_relaxed.owl FYPO:0000937 biolink:NamedThing decreased protein localization to cortical microtubule cytoskeleton during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical microtubule cytoskeleton is decreased. FYPO_relaxed.owl FYPO:0004980 biolink:NamedThing decreased protein localization to eMTOC during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the equatorial microtubule organizing center is decreased. FYPO_relaxed.owl FYPO:0001677 biolink:NamedThing increased protein localization to medial cortex during vegetative growth A cell phenotype in which the localization of a protein to the medial cortex is increased in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0004854 biolink:NamedThing increased protein localization to actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is increased. FYPO_relaxed.owl FYPO:0006081 biolink:NamedThing increased protein localization to actin cortical patch A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is increased. FYPO_relaxed.owl FYPO:0009061 biolink:NamedThing increased protein localization to cell cortex during mitotic interphase A cell phenotype observed in mitotic interphase in which the localization of a protein to the cell cortex is increased. FYPO_relaxed.owl FYPO:0002557 biolink:NamedThing decreased protein localization to medial cortex during vegetative growth A cell phenotype in which the localization of a protein to the medial cortex is decreased in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0002699 biolink:NamedThing decreased protein localization to actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is decreased. FYPO_relaxed.owl FYPO:0005798 biolink:NamedThing decreased protein localization to cell cortex of cell tip during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips is decreased. FYPO_relaxed.owl FYPO:0006120 biolink:NamedThing decreased protein localization to actin cortical patch A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is decreased. FYPO_relaxed.owl FYPO:0000940 biolink:NamedThing decreased protein localization to mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased. FYPO_relaxed.owl FYPO:0001875 biolink:NamedThing decreased asymmetric protein localization, with protein localized to both mitotic spindle pole bodies A cell phenotype observed in the vegetative growth phase of the life cycle in which the preferential localization of a protein to either the old or new spindle pole body is decreased. FYPO_relaxed.owl FYPO:0002825 biolink:NamedThing decreased protein localization to mitotic spindle A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle is decreased. FYPO_relaxed.owl FYPO:0006182 biolink:NamedThing decreased protein localization to interphase microtubule A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a cytoplasmic microtubule is decreased during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004092 biolink:NamedThing abolished protein localization to horsetail-astral microtubule array A cell phenotype in which the localization of a protein to the horsetail-astral microtubule array is abolished. FYPO_relaxed.owl FYPO:0000939 biolink:NamedThing abnormal protein localization to mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is abnormal. FYPO_relaxed.owl FYPO:0002770 biolink:NamedThing decreased protein localization to spindle pole body A cell phenotype in which the localization of a protein to the spindle pole body is decreased. FYPO_relaxed.owl FYPO:0005700 biolink:NamedThing abolished protein localization to eMTOC A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the equatorial microtubule organizing center (eMTOC) does not occur. FYPO_relaxed.owl FYPO:0005701 biolink:NamedThing abolished protein localization to iMTOC A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the interphase microtubule organizing center does not occur. FYPO_relaxed.owl FYPO:0000941 biolink:NamedThing abolished protein localization to mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body does not occur. FYPO_relaxed.owl FYPO:0001837 biolink:NamedThing increased duration of protein localization to mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the mitotic spindle pole body for a longer time than normal. FYPO_relaxed.owl FYPO:0001874 biolink:NamedThing abnormal asymmetric protein localization, with protein localized to both mitotic spindle pole bodies A cell phenotype observed in the vegetative growth phase of the life cycle in which the preferential localization of a protein to either the old or new spindle pole body is abnormal. FYPO_relaxed.owl FYPO:0002970 biolink:NamedThing increased protein localization to mitotic spindle pole body during metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is increased during metaphase. FYPO_relaxed.owl FYPO:0005096 biolink:NamedThing increased duration of protein localization to mitotic spindle pole body during anaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the mitotic spindle pole body for a longer time than normal during anaphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006640 biolink:NamedThing abnormal protein localization to mitotic spindle pole body during anaphase B A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is abnormal during anaphase B of mitosis. FYPO_relaxed.owl FYPO:0006824 biolink:NamedThing premature protein localization to mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body begins earlier than normal. FYPO_relaxed.owl FYPO:0007475 biolink:NamedThing delayed onset of protein localization to mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body begins later than normal. FYPO_relaxed.owl FYPO:0007574 biolink:NamedThing decreased duration of protein localization to mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the mitotic spindle pole body for a shorter time than normal. FYPO_relaxed.owl FYPO:0002772 biolink:NamedThing decreased protein localization to meiotic spindle pole body A cell phenotype in which the localization of a protein to the meiotic spindle pole body is decreased. FYPO_relaxed.owl FYPO:0007257 biolink:NamedThing delayed onset of protein localization to meiotic spindle pole body during meiosis I A cell phenotype in which the localization of a protein to the meiotic spindle pole body begins later than normal during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0003186 biolink:NamedThing abolished protein localization to mitotic spindle A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle does not occur. FYPO_relaxed.owl FYPO:0003269 biolink:NamedThing abolished protein localization to microtubule during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more microtubules does not occur. FYPO_relaxed.owl FYPO:0005817 biolink:NamedThing abolished protein localization to microtubule plus-end during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or both ends end of a microtubule does not occur during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0000943 biolink:NamedThing normal spore morphology A cell phenotype characterized by normal spore morphology, i.e. the size, shape, and structure of the spore are indistinguishable from wild type. FYPO_relaxed.owl FYPO:0002048 biolink:NamedThing normal cell morphology during nitrogen starvation A cell phenotype characterized by normal cell morphology (i.e. size, shape, and structure indistinguishable from wild type) when the cell is subject to nitrogen starvation. Wild-type cells become spherical upon nitrogen starvation, and have a smaller volume than under nitrogen-replete conditions. FYPO_relaxed.owl FYPO:0006286 biolink:NamedThing normal cyclin B1-CDK1 complex level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain a normal (i.e. indistinguishable from wild type) number of protein complexes consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1). FYPO_relaxed.owl FYPO:0008119 biolink:NamedThing normal morphology during phosphate starvation A cell phenotype characterized by normal cell morphology (i.e. size, shape, and structure indistinguishable from wild type) when the cell is subject to phophate starvation. FYPO_relaxed.owl FYPO:0002942 biolink:NamedThing swollen spheroid cell during G0 A cell morphology phenotype in which a cell is shaped in the form of a spheroid, and has a larger volume than normal, when the cell is in G0 phase. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged. FYPO_relaxed.owl FYPO:0002943 biolink:NamedThing swollen spheroid cell during G0 to G1 transition A cell morphology phenotype in which a cell is shaped in the form of a spheroid, and has a larger volume than normal, when the cell undergoes transition from G0 phase to G1. In spheroid cells, there is much less difference between the long and short axes of the cell than in wild type. Spheroid cells may shorter than normal, with approximately the same diameter as normal, or they may be enlarged. FYPO_relaxed.owl FYPO:0001510 biolink:NamedThing viable vegetative cell, abnormal cell shape, normal cell size A cell phenotype in which a cell is viable, cell shape is altered, and cell size remains normal, in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001511 biolink:NamedThing inviable vegetative cell, abnormal cell shape, normal cell size A cell phenotype in which a cell is inviable, cell shape is altered, and cell size remains normal, in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0000947 biolink:NamedThing swollen spherical vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a sphere, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0000948 biolink:NamedThing normal volume spherical vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a sphere, and has a normal volume. FYPO_relaxed.owl FYPO:0004103 biolink:NamedThing viable spherical vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable, and shaped in the form of a sphere. FYPO_relaxed.owl FYPO:0004104 biolink:NamedThing inviable spherical vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable, and shaped in the form of a sphere. FYPO_relaxed.owl FYPO:0002190 biolink:NamedThing inviable swollen spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is shaped in the form of a spheroid, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0002240 biolink:NamedThing swollen septated spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid, has one or more septa, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0004559 biolink:NamedThing viable swollen spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, is shaped in the form of a spheroid, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0002187 biolink:NamedThing inviable normal volume spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is shaped in the form of a spheroid, and has a normal volume. FYPO_relaxed.owl FYPO:0002189 biolink:NamedThing viable normal volume spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, is shaped in the form of a spheroid, and has a normal volume. FYPO_relaxed.owl FYPO:0002241 biolink:NamedThing normal volume septated spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid, has one or more septa, and has a normal volume. FYPO_relaxed.owl FYPO:0006192 biolink:NamedThing normal volume aseptate spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is shaped in the form of a spheroid, has no septum, and has a normal volume. FYPO_relaxed.owl FYPO:0003682 biolink:NamedThing inviable after spore germination, without cell division, elongated multinucleate aseptate cell A phenotype in which a spore germinates to produce an inviable cell that does not divide, is elongated, does not contain a septum, and contains more than one nucleus. FYPO_relaxed.owl FYPO:0003785 biolink:NamedThing aseptate mononucleate vegetative cell A cell phenotype in which a cell contains one nucleus and no septum. FYPO_relaxed.owl FYPO:0004562 biolink:NamedThing binucleate aseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and no septum. FYPO_relaxed.owl FYPO:0000965 biolink:NamedThing abnormal histone H3-K14 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere outer repeat regions is abnormal. FYPO_relaxed.owl FYPO:0001458 biolink:NamedThing decreased histone H3-K14 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007222 biolink:NamedThing decreased histone H3-K14 acetylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in regions containing protein-coding genes occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0000966 biolink:NamedThing increased histone H3-K14 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0000967 biolink:NamedThing decreased histone H3-K14 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere outer repeat regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0003802 biolink:NamedThing increased histone H3-K14 acetylation at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in telomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005518 biolink:NamedThing increased histone H3-K14 acetylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in regions containing protein coding genes occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006815 biolink:NamedThing increased histone H3-K14 acetylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere inner repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007307 biolink:NamedThing increased histone H3-K14 acetylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007633 biolink:NamedThing increased histone H3-K14 acetylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 14 of histone H3 at the silent mating-type cassettes occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007634 biolink:NamedThing increased histone H3-K14 acetylation at rDNA during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 14 of histone H3 at ribosomal DNA occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005011 biolink:NamedThing decreased histone H4 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H4 acetylation occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005533 biolink:NamedThing decreased histone H4-K16 acetylation at boundary element IRC1L during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 at the IRC1L boundary element occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001705 biolink:NamedThing normal mitotic DNA damage checkpoint A cell cycle checkpoint phenotype in which any mitotic DNA damage checkpoint is normal (i.e. indistinguishable from wild type). A DNA damage checkpoint normally regulates progression through the cell cycle in response to DNA damage. FYPO_relaxed.owl FYPO:0005192 biolink:NamedThing normal cellular response to nitrogen starvation A stress response phenotype in which the response to nitrogen starvation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000972 biolink:NamedThing increased number of Rad52 foci during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal. FYPO_relaxed.owl FYPO:0001031 biolink:NamedThing accumulation of single-strand break sites A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites of single-strand breaks in DNA is greater than normal. FYPO_relaxed.owl FYPO:0002573 biolink:NamedThing increased number of Ssb1 foci A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Ssb1 accumulates is greater than normal. FYPO_relaxed.owl FYPO:0003580 biolink:NamedThing increased number of Sad1 foci during response to DNA damage A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Sad1 accumulates is greater than normal during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0003581 biolink:NamedThing increased number of Kms1 foci A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Kms1 accumulates is greater than normal. FYPO_relaxed.owl FYPO:0004516 biolink:NamedThing decreased number of Rad52 foci during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is lower than normal. FYPO_relaxed.owl FYPO:0004524 biolink:NamedThing decreased number of Rad54 foci during cellular response to doxorubicin A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad54 (also called Rhp54) accumulates is lower than normal during a cellular response to doxorubicin. FYPO_relaxed.owl FYPO:0004869 biolink:NamedThing decreased number of Crb2 foci during cellular response to ionizing radiation A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Crb2 accumulates is lower than normal during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0004951 biolink:NamedThing increased number of Brc1 foci A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Brc1 accumulates is greater than normal. FYPO_relaxed.owl FYPO:0005334 biolink:NamedThing increased number of Holliday junctions A cell phenotype observed in the vegetative growth phase of the life cycle in which the Holliday junctions is greater than normal. A Holliday junction is a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. FYPO_relaxed.owl FYPO:0005388 biolink:NamedThing decreased number of Rad51 foci during cellular response to ionizing radiation A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad51 accumulates is lower than normal during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0005389 biolink:NamedThing increased number of Rqh1 foci during cellular response to ionizing radiation A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rqh1 accumulates is greater than normal during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0005605 biolink:NamedThing increased duration of Ssb1 focus presence during cellular response to ionizing radiation A cell phenotype observed in the vegetative growth phase of the life cycle in which sites at which the protein Ssb1 accumulates remain present for longer than normal during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0006421 biolink:NamedThing decreased number of Fbh1 foci during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Fbh1 (also called Rad22) accumulates is lower than normal. FYPO_relaxed.owl FYPO:0006925 biolink:NamedThing decreased number of Rad51 foci at mitotic DNA replication fork barriers A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad51 accumulates at or near replication fork barriers is lower than normal. FYPO_relaxed.owl FYPO:0006926 biolink:NamedThing increased nucleus:cytoplasm ratio A cell phenotype observed in the vegetative growth phase of the life cycle in which the ratio of the nuclear volume to the total cell volume is greater than normal (the ration observed in wild type is approximately 0.076-0.089). FYPO_relaxed.owl FYPO:0006927 biolink:NamedThing decreased nucleus:cytoplasm ratio A cell phenotype observed in the vegetative growth phase of the life cycle in which the ratio of the nuclear volume to the total cell volume is lower than normal (the ration observed in wild type is approximately 0.076-0.089). FYPO_relaxed.owl FYPO:0007191 biolink:NamedThing increased duration of Rad52 focus presence during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which sites at which the protein Rad52 accumulates remain present for longer than normal. FYPO_relaxed.owl FYPO:0007381 biolink:NamedThing Ssb1 megafocus present A cell phenotype observed in the vegetative growth phase of the life cycle in which the protein Ssb1 accumulates in a large focus, or occasionally two foci, in the nucleus. FYPO_relaxed.owl FYPO:0007710 biolink:NamedThing decreased number of Ssb1 foci A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Ssb1 accumulates is lower than normal. FYPO_relaxed.owl FYPO:0004710 biolink:NamedThing increased number of Rad52 foci during G0 to G1 transition A cell phenotype observed when the cell undergoes transition from G0 phase to G1 in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal. FYPO_relaxed.owl FYPO:0000973 biolink:NamedThing normal cellular response to copper ion A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to copper ions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000974 biolink:NamedThing normal cellular response to zinc ion A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to zinc ions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000975 biolink:NamedThing normal cellular response to mercury ion A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to mercury ions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000976 biolink:NamedThing normal cellular response to selenite ion A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to selenite ions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000977 biolink:NamedThing normal cellular response to silver ion A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to silver ions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000988 biolink:NamedThing normal cellular response to arsenic A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to arsenic is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001455 biolink:NamedThing normal cellular response to water deprivation A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to water deprivation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001485 biolink:NamedThing normal cellular response to oxidative stress A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to oxidative stress is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001857 biolink:NamedThing normal transcription during cellular response to iron A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to iron ions. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0001926 biolink:NamedThing normal cellular response to hydroxyurea A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to hydroxyurea is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0000992 biolink:NamedThing altered cellular phosphatidylinositol-3-phosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3-phosphate measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0001290 biolink:NamedThing altered cellular phosphoinositide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phosphoinositide measured in a cell differs from normal. A phosphoinositide is any phosphatidylinositol that is phosphorylated at one or more of the hydroxy groups of inositol. FYPO_relaxed.owl FYPO:0001015 biolink:NamedThing altered cellular phosphatidylinositol-4-phosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0001286 biolink:NamedThing increased cellular phosphoinositide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phosphoinositide measured in a cell is higher than normal. A phosphoinositide is any phosphatidylinositol that is phosphorylated at one or more of the hydroxy groups of inositol. FYPO_relaxed.owl FYPO:0005588 biolink:NamedThing decreased cellular phosphoinositide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phosphoinositide measured in a cell is lower than normal. A phosphoinositide is any phosphatidylinositol that is phosphorylated at one or more of the hydroxy groups of inositol. FYPO_relaxed.owl FYPO:0000993 biolink:NamedThing decreased cellular phosphatidylinositol-3-phosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3-phosphate measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006222 biolink:NamedThing decreased phosphatidylinositol phosphate level in plasma membrane A cell phenotype in which the amount of one or more phosphatidylinositol phosphates measured in the plasma membrane is higher than normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0006485 biolink:NamedThing decreased cellular phosphatidylinositol-3,4-bisphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3,4-bisphosphate measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006486 biolink:NamedThing decreased cellular phosphatidylinositol-3,4,5-trisphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3,4,5-trisphosphate measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006775 biolink:NamedThing decreased cellular phosphatidylinositol-4-phosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0008041 biolink:NamedThing decreased cellular phosphatidylinositol-4,5-bisphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4,5-bisphosphate measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0000994 biolink:NamedThing increased cellular phosphatidylinositol-4-phosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006487 biolink:NamedThing increased cellular phosphatidylinositol-3,4-bisphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3,4-bisphosphate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006488 biolink:NamedThing increased cellular phosphatidylinositol-3,4,5-trisphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3,4,5-trisphosphate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006624 biolink:NamedThing increased phosphatidylinositol-3,4,5-trisphosphate level in plasma membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3,4,5-trisphosphate measured in the plasma membrane is higher than normal. FYPO_relaxed.owl FYPO:0006626 biolink:NamedThing increased phosphatidylinositol-4,5-bisphosphate level in plasma membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4,5-bisphosphate measured in the plasma membrane is higher than normal. FYPO_relaxed.owl FYPO:0008040 biolink:NamedThing increased cellular phosphatidylinositol-4,5-bisphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4,5-bisphosphate measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0000996 biolink:NamedThing tapered cell during nitrogen starvation A cell morphology phenotype in which the cell tapers at one end to a diameter smaller than the other when the cell is subject to nitrogen starvation. The cell diameter at the narrow end is smaller than that of a wild-type cell. FYPO_relaxed.owl FYPO:0000997 biolink:NamedThing pear-shaped cell during nitrogen starvation A cell morphology phenotype in which a cell is shaped in the form of a pear when the cell is subject to nitrogen starvation. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell. FYPO_relaxed.owl FYPO:0000998 biolink:NamedThing elongated cell during nitrogen starvation A cell morphology phenotype in which a cell becomes elongated, i.e. has a greater length and length:diameter ratio than normal, when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0003160 biolink:NamedThing elongated cell during stationary phase A cell morphology phenotype in which a cell is elongated, i.e. has a greater length and length:diameter ratio than normal, when the cell is in a culture in stationary phase. FYPO_relaxed.owl FYPO:0005077 biolink:NamedThing elongated cell during glucose starvation A cell morphology phenotype in which a cell becomes elongated, i.e. has a greater length and length:diameter ratio than normal, when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0007786 biolink:NamedThing elongated cell with cell cycle arrest at meiotic G2/MI transition A cell phenotype in which the cell is longer than normal, and progression through the meiotic cell cycle is arrested at the G2/MI phase transition. A cell can elongate when arrested at the G2/MI transition if it overcomes the growth arrest that usually occurs. FYPO_relaxed.owl FYPO:0001151 biolink:NamedThing cell cycle arrest at mitotic G2/M phase transition during starvation A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition when the cell is subject to starvation for one or more nutrients. FYPO_relaxed.owl FYPO:0002108 biolink:NamedThing viable tapered cell A cell morphology phenotype in which a cell is viable, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell. FYPO_relaxed.owl FYPO:0005664 biolink:NamedThing viable elongated cell during nitrogen starvation A cell morphology phenotype in which a cell is viable, and becomes elongated, i.e. has a greater length and length:diameter ratio than normal, when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006935 biolink:NamedThing viable cell with normal cell morphology during nitrogen starvation A cell phenotype in which a cell has normal volume, dimensions and shape, and is viable, when subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0001005 biolink:NamedThing fragmented DNA during nitrogen starvation A cell phenotype in which DNA is broken into small fragments when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0004694 biolink:NamedThing fragmented DNA during stationary phase A cell phenotype in which DNA is broken into small fragments when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0004928 biolink:NamedThing fragmented DNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which DNA is broken into small fragments. FYPO_relaxed.owl FYPO:0001006 biolink:NamedThing inviable elongated multinucleate vegetative cell with central constriction A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than one nucleus, is elongated, is inviable, and has an abnormal shape featuring a constriction at the center of the cell, corresponding to the cell division site. In a cell with this phenotype, the diameter at the ends may be much greater than in wild-type cells. Septal material may accumulate in patches at the cell surface, but no septum forms. FYPO_relaxed.owl FYPO:0004684 biolink:NamedThing inviable elongated binucleate aseptate cell A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is elongated, and has two nuclei but no septum. FYPO_relaxed.owl FYPO:0006630 biolink:NamedThing inviable elongated tetranucleate aseptate vegetative cell A cell morphology phenotype in which a vegetative cell is inviable, elongated, has no septum, and contains four nuclei. FYPO_relaxed.owl FYPO:0001017 biolink:NamedThing premature NETO A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) begins earlier than normal. FYPO_relaxed.owl FYPO:0003150 biolink:NamedThing decreased NETO A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007240 biolink:NamedThing abnormal NETO in daughter cells A cell polarity phenotype in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) differs between the two daughter cells formed as a result of cell division. Normally, growth begins at the old end and then becomes bipolar with similar timing in both daughter cells. FYPO_relaxed.owl FYPO:0001019 biolink:NamedThing monopolar actin cortical patch localization during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized to only one end of a cell. FYPO_relaxed.owl FYPO:0002021 biolink:NamedThing dispersed actin cortical patch localization during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized throughout the cell cortex (rather than concentrated at the cell ends as in wild type cells). FYPO_relaxed.owl FYPO:0005430 biolink:NamedThing aggregated actin cortical patches during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches cluster together more than normal. FYPO_relaxed.owl FYPO:0006092 biolink:NamedThing polarized actin cortical patch localization during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized more towards the end of the cell, with fewer patches in the lateral cortex, than normal. FYPO_relaxed.owl FYPO:0001022 biolink:NamedThing normal growth during cellular response to high osmolarity A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to high osmolarity. FYPO_relaxed.owl FYPO:0001037 biolink:NamedThing normal growth during cellular response to salt stress A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to salt stress. FYPO_relaxed.owl FYPO:0001472 biolink:NamedThing normal growth on tacrolimus during osmotic stress A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tacrolimus during a cellular response to osmotic stress. FYPO_relaxed.owl FYPO:0002079 biolink:NamedThing normal growth on calcium during cellular hypotonic response A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing calcium ions during a cellular hypotonic response. FYPO_relaxed.owl FYPO:0001033 biolink:NamedThing normal double-strand break repair A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003174 biolink:NamedThing normal nucleotide-excision repair during cellular response to UV A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleotide-excision repair is normal (i.e. indistinguishable from wild type) during a cellular response to ultraviolet light. Nucleotide-excision repair is a DNA repair process in which a small region of the strand surrounding the damage is removed as an oligonucleotide, and the resulting small gap is filled in by the sequential action of DNA polymerase and DNA ligase. FYPO_relaxed.owl FYPO:0005325 biolink:NamedThing normal error-free translesion synthesis A cell phenotype observed in the vegetative growth phase of the life cycle in which error-free translesion synthesis is normal (i.e. indistinguishable from wild type). Error-free translesion synthesis a DNA repair process that results in the conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across from the lesion. FYPO_relaxed.owl FYPO:0005326 biolink:NamedThing normal error-prone translesion synthesis A cell phenotype observed in the vegetative growth phase of the life cycle in which error-prone translesion synthesis is normal (i.e. indistinguishable from wild type). Error-prone translesion synthesis a DNA repair process that results in the conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. FYPO_relaxed.owl FYPO:0006570 biolink:NamedThing normal UV-damage excision repair A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UV-damage excision repair is normal (i.e. indistinguishable from wild type). UV-damage excision repair is a DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site, and that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs). FYPO_relaxed.owl FYPO:0001035 biolink:NamedThing increased cell wall thickness during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is thicker than normal. FYPO_relaxed.owl FYPO:0006745 biolink:NamedThing abnormal cell wall thickness during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the thickness of the cell wall is abnormal. The wall may be uniformly thicker or thinner than normal, or thickness may be irregular. FYPO_relaxed.owl FYPO:0002163 biolink:NamedThing decreased cell wall thickness during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is thinner than normal. FYPO_relaxed.owl FYPO:0001036 biolink:NamedThing delaminated cell wall during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is delaminated, i.e. one or more of its layers peels off. FYPO_relaxed.owl FYPO:0002630 biolink:NamedThing irregular cell wall during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the outer surface of the fungal-type cell wall is rougher and less regular than normal. FYPO_relaxed.owl FYPO:0003697 biolink:NamedThing cell wall invagination into cytoplasm A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which one or more extensions of the cell wall protrude into the cytoplasm. The cell wall extensions do not form a normal septum. FYPO_relaxed.owl FYPO:0002961 biolink:NamedThing delaminated cell wall during G0 A physical cellular phenotype in which the fungal-type cell wall is delaminated, i.e. one or more of its layers peels off, when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0001838 biolink:NamedThing decreased protein phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0002830 biolink:NamedThing delayed onset of protein phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, begins later than normal. FYPO_relaxed.owl FYPO:0003019 biolink:NamedThing abnormal protein autophosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the autophosphorylation of one or more specific proteins, or of specific protein sites, is abnormal. Protein autophosphorylation is the phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. FYPO_relaxed.owl FYPO:0005615 biolink:NamedThing abnormal protein phosphorylation during cellular response to bleomycin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, is abnormal during a cellular response to bleomycin. FYPO_relaxed.owl FYPO:0002681 biolink:NamedThing increased protein phosphorylation during nitrogen starvation A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0003565 biolink:NamedThing increased protein phosphorylation during meiosis I A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0005197 biolink:NamedThing increased protein phosphorylation during glucose starvation A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a greater extent than normal when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0001042 biolink:NamedThing inviable after spore germination, single or double cell division A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and then dies. FYPO_relaxed.owl FYPO:0002430 biolink:NamedThing inviable after spore germination, multiple cell divisions A phenotype in which a spore germinates to produce a cell that undergoes two or more rounds of cell division, and then dies. FYPO_relaxed.owl FYPO:0001044 biolink:NamedThing abnormal acid phosphatase activity A molecular function phenotype in which the observed rate of acid phosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0001756 biolink:NamedThing abnormal protein phosphatase activity A molecular function phenotype in which the observed rate of protein phosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0002165 biolink:NamedThing abnormal polynucleotide 3'-phosphatase activity A molecular function phenotype in which the observed rate of polynucleotide 3'-phosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0004298 biolink:NamedThing abnormal polynucleotide 5'-phosphatase activity A molecular function phenotype in which the observed rate of polynucleotide 5'-phosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0005482 biolink:NamedThing abnormal inositol phosphate phosphatase activity A molecular function phenotype in which the observed rate of an inositol phosphate phosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0007040 biolink:NamedThing abnormal alkaline phosphatase activity A molecular function phenotype in which the observed rate of alkaline phosphatase activity is abnormal. FYPO_relaxed.owl FYPO:0001045 biolink:NamedThing decreased acid phosphatase activity A molecular function phenotype in which the observed rate of acid phosphatase activity is decreased. FYPO_relaxed.owl FYPO:0002243 biolink:NamedThing increased acid phosphatase activity A molecular function phenotype in which the observed rate of acid phosphatase activity is increased. FYPO_relaxed.owl FYPO:0002244 biolink:NamedThing abolished acid phosphatase activity A molecular function phenotype in which acid phosphatase activity is absent. FYPO_relaxed.owl FYPO:0001757 biolink:NamedThing decreased protein phosphatase activity A molecular function phenotype in which the observed rate of a protein phosphatase activity is decreased. FYPO_relaxed.owl FYPO:0004413 biolink:NamedThing decreased phosphatase activity during cellular response to phosphate starvation A molecular function phenotype in which the observed rate of a phosphatase activity is decreased during a cellular response to phosphate starvation. FYPO_relaxed.owl FYPO:0004829 biolink:NamedThing decreased phosphatase activity during cellular response to adenine starvation A molecular function phenotype in which the observed rate of a phosphatase activity is decreased during a cellular response to adenine starvation. FYPO_relaxed.owl FYPO:0005484 biolink:NamedThing decreased inositol phosphate phosphatase activity A molecular function phenotype in which the observed rate of an inositol phosphate phosphatase activity is decreased. FYPO_relaxed.owl FYPO:0007042 biolink:NamedThing decreased alkaline phosphatase activity A molecular function phenotype in which the observed rate of alkaline phosphatase activity is decreased. FYPO_relaxed.owl FYPO:0001046 biolink:NamedThing premature mitosis A cellular process phenotype in which cells enter mitosis earlier, relative to cell size or DNA integrity checkpoint status, than normal. FYPO_relaxed.owl FYPO:0003165 biolink:NamedThing cut with abnormal chromosome segregation An inviable phenotype in which a cell undergoes mitotic catastrophe (i.e. enters mitosis prematurely and with defective chromosome segregation), and then septates to give rise to a cut phenotype. In a cut phenotype, a cell undergoes septation despite abnormal mitosis, such that the septum physically divides the nucleus into two parts, and produces inviable daughter cells. FYPO_relaxed.owl FYPO:0001052 biolink:NamedThing cut, small cell An inviable phenotype in which a cell enters mitosis when smaller than wild type, and then septates to give rise to a cut phenotype. In a cut phenotype, a cell undergoes septation despite abnormal mitosis such that the septum physically divides the nucleus into two parts. FYPO_relaxed.owl FYPO:0002483 biolink:NamedThing inviable small tapered vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable, has an abnormally low volume, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell. FYPO_relaxed.owl FYPO:0007700 biolink:NamedThing inviable small vegetative cell with premature mitotic G2/M phase transition A cell phenotype in which a vegetative cell is inviable and an abnormally low volume, and in which the G2/M transition of the mitotic cell cycle begins earlier than normal. FYPO_relaxed.owl FYPO:0001055 biolink:NamedThing cut following normal mitotic chromosome condensation An inviable phenotype in which a cell enters mitosis normally, in that the spindle forms normally and chromosomes condense normally, but then undergoes septation despite abnormal chromosome segregation, giving rise to a cut phenotype. FYPO_relaxed.owl FYPO:0004592 biolink:NamedThing cut following normal mitosis An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell becomes cut after it has undergone a normal mitotic nuclear division and passed through the subsequent mitotic interphase. In a cut phenotype, a cell undergoes septation despite abnormal chromosome segregation. FYPO_relaxed.owl FYPO:0006692 biolink:NamedThing cut with septum between unequally sized nuclei An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes septation despite abnormal mitotic sister chromatid separation, producing inviable daughter cells, and in which the septum forms so as to separate the nucleus into two unequal masses, each in one compartment. FYPO_relaxed.owl FYPO:0001597 biolink:NamedThing normal valine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which valine import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001598 biolink:NamedThing normal glutamine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which glutamine import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001599 biolink:NamedThing normal asparagine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which asparagine import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001600 biolink:NamedThing normal isoleucine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which isoleucine import into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003259 biolink:NamedThing normal proline import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of proline into the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001058 biolink:NamedThing decreased amino acid import A cellular process phenotype in which the import of one or more amino acids into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001646 biolink:NamedThing abnormal glutamate import A cellular process phenotype in which the import of glutamate into the cell is abnormal. FYPO_relaxed.owl FYPO:0001648 biolink:NamedThing abnormal amino acid import during nitrogen starvation A cellular process phenotype in which the import of one or more amino acids into the cell is abnormal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0001651 biolink:NamedThing abnormal lysine import A cellular process phenotype in which the import of lysine into the cell is abnormal. FYPO_relaxed.owl FYPO:0001059 biolink:NamedThing abnormal glutamate import during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutamate into the cell is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001061 biolink:NamedThing abnormal glutamine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutamine into the cell is abnormal. FYPO_relaxed.owl FYPO:0001063 biolink:NamedThing abnormal glycine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glycine into the cell is abnormal. FYPO_relaxed.owl FYPO:0001065 biolink:NamedThing abnormal threonine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of threonine into the cell is abnormal. FYPO_relaxed.owl FYPO:0001067 biolink:NamedThing abnormal tyrosine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of tyrosine into the cell is abnormal. FYPO_relaxed.owl FYPO:0001139 biolink:NamedThing abnormal leucine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of leucine into the cell is abnormal. FYPO_relaxed.owl FYPO:0001360 biolink:NamedThing decreased amino acid import during vegetative growth A cellular process phenotype in which the import of one or more amino acids into the cell occurs to a lower extent than normal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001653 biolink:NamedThing abnormal lysine import during vegetative growth A cellular process phenotype in which the import of lysine into the cell is abnormal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001654 biolink:NamedThing abnormal arginine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of arginine into the cell is abnormal. FYPO_relaxed.owl FYPO:0001655 biolink:NamedThing abnormal histidine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of histidine into the cell is abnormal. FYPO_relaxed.owl FYPO:0001656 biolink:NamedThing abnormal asparagine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of asparagine into the cell is abnormal. FYPO_relaxed.owl FYPO:0001657 biolink:NamedThing abnormal serine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of serine into the cell is abnormal. FYPO_relaxed.owl FYPO:0001658 biolink:NamedThing abnormal valine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of valine into the cell is abnormal. FYPO_relaxed.owl FYPO:0003169 biolink:NamedThing increased amino acid import during vegetative growth A cellular process phenotype in which the import of one or more amino acids into the cell occurs to a greater extent than normal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0003256 biolink:NamedThing abnormal proline import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of proline into the cell is abnormal. FYPO_relaxed.owl FYPO:0001647 biolink:NamedThing abnormal glutamate import during nitrogen starvation A cellular process phenotype in which the import of L-glutamate into the cell is abnormal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0001649 biolink:NamedThing decreased glutamate import A cellular process phenotype in which the import of glutamate into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001060 biolink:NamedThing decreased glutamate import during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutamate into the cell occurs to a lower extent than normal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001062 biolink:NamedThing decreased glutamine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glutamine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001064 biolink:NamedThing decreased glycine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glycine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001066 biolink:NamedThing decreased threonine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of threonine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001068 biolink:NamedThing decreased tyrosine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of tyrosine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001140 biolink:NamedThing decreased leucine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of leucine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001590 biolink:NamedThing decreased lysine import during vegetative growth A cellular process phenotype in which the import of lysine into the cell occurs to a lower extent than normal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001591 biolink:NamedThing decreased histidine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of histidine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001592 biolink:NamedThing decreased arginine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of arginine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001593 biolink:NamedThing decreased valine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of valine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001594 biolink:NamedThing decreased asparagine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of asparagine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001595 biolink:NamedThing decreased serine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of serine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0003257 biolink:NamedThing decreased proline import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of proline into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0008016 biolink:NamedThing decreased phenylalanine import during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of phenylalanine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001589 biolink:NamedThing decreased glutamate import during nitrogen starvation A cellular process phenotype in which the import of glutamate into the cell occurs to a lower extent than normal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0002220 biolink:NamedThing increased duration of meiotic cell cycle phase A cellular process phenotype in which the duration of one or more meiotic cell cycle phases is longer than normal. FYPO_relaxed.owl FYPO:0006851 biolink:NamedThing decreased duration of meiotic cell cycle phase A cellular process phenotype in which the duration of one or more meiotic cell cycle phases is shorter than normal. FYPO_relaxed.owl FYPO:0004852 biolink:NamedThing RNA transport phenotype A cell process phenotype that affects an RNA transport process. FYPO_relaxed.owl FYPO:0001074 biolink:NamedThing decreased myo-inositol import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of myo-inositol into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001078 biolink:NamedThing normal beta-glucan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001079 biolink:NamedThing normal galactomannan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001142 biolink:NamedThing normal Man8GlcNAc level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man8GlcNAc2 measured in a cell is normal (i.e. indistinguishable from wild type). Man8GlcNAc2 is any N-glycan that consists of a branched ten-membered mannooligosaccharide containing eight D-mannosyl residues and two N-acetylglucosamine residues. FYPO_relaxed.owl FYPO:0001143 biolink:NamedThing normal Man9GlcNAc level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man9GlcNAc2 measured in a cell is normal (i.e. indistinguishable from wild type). Man9GlcNAc2 is any N-glycan that consists of a branched undecasaccharide consisting of nine D-mannosyl residues and two N-acetylglucosamine residues. FYPO_relaxed.owl FYPO:0001196 biolink:NamedThing normal alpha-glucan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001085 biolink:NamedThing altered polysaccharide level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0001081 biolink:NamedThing decreased cell wall alpha-glucan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in the cell wall is lower than normal. FYPO_relaxed.owl FYPO:0002266 biolink:NamedThing decreased cell wall polysaccharide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more polysaccharides measured in the cell wall is lower than normal. FYPO_relaxed.owl FYPO:0001082 biolink:NamedThing decreased cell wall beta-glucan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in the cell wall is lower than normal. FYPO_relaxed.owl FYPO:0002265 biolink:NamedThing decreased cell wall galactomannan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in the cell wall is lower than normal. FYPO_relaxed.owl FYPO:0001084 biolink:NamedThing increased cell wall alpha-glucan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in the cell wall is greater than normal. FYPO_relaxed.owl FYPO:0004859 biolink:NamedThing increased cell wall polysaccharide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more polysaccharides measured in the cell wall is greater than normal. FYPO_relaxed.owl FYPO:0001977 biolink:NamedThing increased cell wall galactomannan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in the cell wall is greater than normal. FYPO_relaxed.owl FYPO:0004860 biolink:NamedThing increased cell wall beta-glucan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in the cell wall is greater than normal. FYPO_relaxed.owl FYPO:0001287 biolink:NamedThing altered phospholipid level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phospholipid measured in a cell differs from normal. A phospholipid is any lipid containing phosphoric acid as a mono- or di-ester. FYPO_relaxed.owl FYPO:0001411 biolink:NamedThing altered cellular sulfide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sulfide (S2-, also called acid labile sulfide) measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0001448 biolink:NamedThing trehalose absent from cell during heat shock A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0001462 biolink:NamedThing altered cellular calcium level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0001601 biolink:NamedThing altered level of substance in vacuole A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the vacuole differs from normal. FYPO_relaxed.owl FYPO:0001604 biolink:NamedThing altered level of substance in cytosol A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a specific substance measured in the cytosol differs from normal. FYPO_relaxed.owl FYPO:0001811 biolink:NamedThing altered 5-phosphoribosyl diphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5-phosphoribosyl diphosphate measured in a cell differs from normal. FYPO_relaxed.owl FYPO:0002325 biolink:NamedThing altered cellular sterol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a sterol measured in a cell differs from normal. A sterol is any natural product derived from the steroid skeleton and containing a hydroxy group in the 3 position, closely related to cholestan-3-ol. FYPO_relaxed.owl FYPO:0003984 biolink:NamedThing altered cellular amino acid level during vegetative growth A cell phenotype in which the amount of an amino acid measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0005823 biolink:NamedThing increased phosphatidylserine externalization A cell phenotype in which the amount of phosphatidylserine measured in the outer leaflet of the plasma membrane is higher than normal when the cell is in the vegetative growth phase of the life cycle. Normally, phosphatidylserine is restricted to the inner leaflet of the plasma membrane. FYPO_relaxed.owl FYPO:0007901 biolink:NamedThing increased number of R-loops A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA-DNA hybrid molecules is greater than normal. FYPO_relaxed.owl FYPO:0001967 biolink:NamedThing abnormal 1,3-beta-D-glucan synthase activity A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is abnormal. FYPO_relaxed.owl FYPO:0002047 biolink:NamedThing resistance to heat shock during nitrogen starvation A cell phenotype in which cells show decreased sensitivity to heat shock, when the cell is also subject to nitrogen starvation. Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature. FYPO_relaxed.owl FYPO:0001091 biolink:NamedThing normal cellular response to heat shock A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to heat shock is normal (i.e. indistinguishable from wild type). Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature. FYPO_relaxed.owl FYPO:0001202 biolink:NamedThing normal cellular response to calcium starvation A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to calcium starvation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001925 biolink:NamedThing normal cellular response to gamma radiation A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the cellular response to gamma radiation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007398 biolink:NamedThing normal stress-activated MAPK cascade A cellular process phenotype observed in the vegetative growth phase of the life cycle in which signaling via a MAP kinase cascade that is activated in response to stress is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002576 biolink:NamedThing abnormal chromatin binding A molecular function phenotype in which the occurrence of chromatin binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0002577 biolink:NamedThing decreased chromatin binding A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0002980 biolink:NamedThing increased chromatin binding A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0004005 biolink:NamedThing increased spatial extent of chromatin binding A molecular function phenotype in which a gene product binds chromatin over a larger portion of the chromosome than normal. FYPO_relaxed.owl FYPO:0004225 biolink:NamedThing abnormal nucleosome binding A molecular function phenotype in which occurrence of nucleosome binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001094 biolink:NamedThing normal DNA replication origin binding A molecular function phenotype in which occurrence of DNA binding at a replication origin by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007542 biolink:NamedThing normal double-stranded DNA binding A molecular function phenotype in which occurrence of double-stranded DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007202 biolink:NamedThing normal rDNA spacer replication fork barrier binding A molecular function phenotype in which occurrence of DNA binding at an rDNA spacer replication fork barrier by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007382 biolink:NamedThing normal transcription regulatory region sequence-specific DNA binding A molecular function phenotype in which occurrence of DNA binding at a transcription regulatory region by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001095 biolink:NamedThing abolished DNA replication origin binding A molecular function phenotype in which DNA binding at a replication origin by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007543 biolink:NamedThing abolished double-stranded DNA binding A molecular function phenotype in which double-stranded DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002003 biolink:NamedThing abolished RNA polymerase II proximal promoter sequence-specific DNA binding A molecular function phenotype in which DNA binding at an RNA polymerase II proximal promoter by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. An RNA polymerase II proximal promoter is a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II. FYPO_relaxed.owl FYPO:0007204 biolink:NamedThing abolished rDNA spacer replication fork barrier binding A molecular function phenotype in which DNA binding at an rDNA spacer replication fork barrier by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007362 biolink:NamedThing abolished double-stranded DNA bridging A molecular function phenotype in which DNA binding that bridges two double-stranded DNA regions does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001096 biolink:NamedThing normal RNA level during nitrogen starvation A cell phenotype in which the amount of RNA measured in a cell that is subject to nitrogen starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0004171 biolink:NamedThing normal RNA level during glucose starvation A cell phenotype in which the amount of RNA measured in a cell that is subject to glucose starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0004931 biolink:NamedThing normal RNA level during sporulation A cell phenotype in which the amount of RNA measured in a cell during sporulation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0006574 biolink:NamedThing normal RNA level during cellular response to pheromone A cell phenotype in which the amount of RNA measured in a cell during a cellular response to a pheromone is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0006976 biolink:NamedThing normal RNA level during meiotic cell cycle A cell phenotype in which the amount of RNA measured in a cell during the meiotic cell cycle is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0001101 biolink:NamedThing decreased protein level during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hydrogen peroxide is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001274 biolink:NamedThing decreased protein level during cellular response to hypoxia A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hypoxia is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001984 biolink:NamedThing protein absent from cell during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell is too low to detect. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0002012 biolink:NamedThing decreased level of iron ion starvation-repressed proteins A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein encoded by genes normally repressed during iron ion starvation measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0002775 biolink:NamedThing decreased level of sumoylated protein in cell A cell phenotype in which the amount of sumoylated protein measured the cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0002847 biolink:NamedThing decreased protein level in proteasome A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the proteasome is lower than normal. FYPO_relaxed.owl FYPO:0003007 biolink:NamedThing decreased protein level during cellular response to caffeine A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to caffeine is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003143 biolink:NamedThing decreased protein level during cellular response to methyl methanesulfonate A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to methyl methanesulfonate is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003151 biolink:NamedThing decreased protein level during cellular response to heat A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to heat is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003447 biolink:NamedThing decreased level of glycosylated protein in cell A cell phenotype in which the amount of glycosylated protein measured the cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003650 biolink:NamedThing decreased protein level during cellular response to glucose starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to glucose starvation is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003651 biolink:NamedThing decreased protein level during cellular response to nitrosative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to nitrosative stress is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003681 biolink:NamedThing decreased protein level at centromere outer repeat heterochromatin A cell phenotype in which the amount of a protein found associated with chromatin at the centromere outer repeat heterochromatin is lower than normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0003915 biolink:NamedThing decreased mitochondrial protein level A cell phenotype in which the amount of protein measured in the mitochondrion is lower than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003930 biolink:NamedThing decreased protein level during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to salt stress is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004007 biolink:NamedThing decreased protein level during cellular response to menadione A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to menadione is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004037 biolink:NamedThing decreased protein level during cellular response to mercury ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to mercury ions is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004124 biolink:NamedThing decreased protein level during cellular response to cadmium ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to cadmium ions is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004156 biolink:NamedThing decreased protein level during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during mitosis is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004190 biolink:NamedThing decreased protein level during cellular response to ionizing radiation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to ionizing radiation is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004193 biolink:NamedThing decreased protein level during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during S phase of the mitotic cell cycle is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004194 biolink:NamedThing decreased protein level during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hydroxyurea is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004451 biolink:NamedThing decreased protein level during cellular response to calcium ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to calcium ions is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004578 biolink:NamedThing decreased level of histone H3 in cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H3 measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0005001 biolink:NamedThing decreased cellular HMW ubiquitin conjugate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein having high molecular mass due to polyubiquitin conjugation is lower than normal. FYPO_relaxed.owl FYPO:0005004 biolink:NamedThing decreased protein level in anaphase-promoting complex A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the anaphase-promoting complex is lower than normal. FYPO_relaxed.owl FYPO:0005102 biolink:NamedThing decreased protein level at silent mating-type cassette A cell phenotype in which the amount of a protein found associated with chromatin at the mating type region is lower than normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0005218 biolink:NamedThing decreased level of histone H2A in cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H2A measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0005226 biolink:NamedThing decreased level of ubiquitinated protein in cell A cell phenotype in which the amount of ubiquitinated protein measured the cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005368 biolink:NamedThing decreased level of iron ion starvation-induced proteins A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein encoded by genes normally induced during iron ion starvation measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0005476 biolink:NamedThing decreased filamentous actin level A cell phenotype in which the amount of filamentous actin measured the cell is lower than normal when the cell is in the vegetative growth phase of the life cycle. The total actin level (globular and filamentous actin) may be normal or abnormal. FYPO_relaxed.owl FYPO:0005630 biolink:NamedThing decreased cellular HMW SUMO conjugate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein having high molecular mass due to polySUMO conjugation is lower than normal. FYPO_relaxed.owl FYPO:0005910 biolink:NamedThing decreased protein level during cellular response to endoplasmic reticulum stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to endoplasmic reticulum stress is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005933 biolink:NamedThing decreased protein level during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G1 phase of the mitotic cell cycle is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0006288 biolink:NamedThing decreased protein level during mitotic G2 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G2 phase of the mitotic cell cycle is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0006328 biolink:NamedThing decreased protein level in spliceosomal complex A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in any spliceosomal complex is lower than normal. FYPO_relaxed.owl FYPO:0006782 biolink:NamedThing decreased protein level in large ribosomal subunit precursor A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in a complex that is a precursor of the large ribosomal subunit is lower than normal. FYPO_relaxed.owl FYPO:0006812 biolink:NamedThing decreased protein level in RNA polymerase II core complex A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the RNA polymerase II core complex is lower than normal. FYPO_relaxed.owl FYPO:0006846 biolink:NamedThing decreased total protein level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of protein measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006885 biolink:NamedThing decreased protein level at mitotic spindle A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured at or associated with the mitotic spindle is lower than normal. FYPO_relaxed.owl FYPO:0006944 biolink:NamedThing decreased ribosomal protein level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount on one or more ribosomal proteins measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0007053 biolink:NamedThing decreased protein level during cellular response to zinc ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to zinc ion starvation is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007067 biolink:NamedThing decreased protein level during stress response to zinc ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular stress response to zinc ions is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007116 biolink:NamedThing decreased protein level in actomyosin contractile ring during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein in the actomyosin contractile ring is lower than normal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007324 biolink:NamedThing decreased level of histone H4 in cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H4 measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0007523 biolink:NamedThing decreased protein level during cellular response to oxidative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to oxidative stress is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007825 biolink:NamedThing decreased protein level during cellular response to amino acid starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to amino acid starvation is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001548 biolink:NamedThing altered protein level during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell differs from normal during a cellular response to hydrogen peroxide. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001107 biolink:NamedThing decreased glutathione-disulfide reductase activity A molecular function phenotype in which the observed rate of glutathione-disulfide reductase activity is decreased. FYPO_relaxed.owl FYPO:0001108 biolink:NamedThing increased glutathione-disulfide reductase activity A molecular function phenotype in which the observed rate of glutathione-disulfide reductase activity is increased. FYPO_relaxed.owl FYPO:0001110 biolink:NamedThing inviable after spore germination, multiple cell divisions, normal morphology A phenotype in which a spore germinates to produce a cell of normal morphology (i.e. size, shape, and structure) that undergoes two or more rounds of cell division, and then dies. FYPO_relaxed.owl FYPO:0002148 biolink:NamedThing inviable after spore germination, multiple cell divisions, abnormal morphology A phenotype in which a spore germinates to produce a cell of abnormal morphology (i.e. size, shape, or structure) that undergoes two or more rounds of cell division, and then dies. FYPO_relaxed.owl FYPO:0003742 biolink:NamedThing inviable after spore germination, multiple cell divisions, unequal chromosome segregation A phenotype in which a spore germinates to produce a cell that undergoes two or more rounds of cell division during which chromosomes segregate unequally, and then dies. FYPO_relaxed.owl FYPO:0004118 biolink:NamedThing inviable after spore germination, multiple cell divisions, normal septum morphology A phenotype in which a spore germinates to produce an inviable cell that has one or more septa with normal size, shape, or structure, and that undergoes two or more rounds of cell division, and then dies. FYPO_relaxed.owl FYPO:0004627 biolink:NamedThing inviable after spore germination, multiple cell divisions, chromosome fragmentation upon segregation A phenotype in which a spore germinates to produce a cell that undergoes two or more rounds of cell division during which chromosomes are broken during mitotic chromosome segregation, and then dies. FYPO_relaxed.owl FYPO:0005088 biolink:NamedThing inviable after spore germination, multiple cell divisions, binucleate septated cell A phenotype in which a spore germinates to produce a cell that contains two nuclei and one or more septa, and undergoes two or more rounds of cell division, and then dies. FYPO_relaxed.owl FYPO:0005185 biolink:NamedThing inviable after spore germination, multiple cell divisions, septated cell with condensed chromatin A phenotype in which a spore germinates to produce a cell that contains one or more septa, has condensed chromatin, and undergoes two or more rounds of cell division, and then dies. FYPO_relaxed.owl FYPO:0006878 biolink:NamedThing inviable after spore germination, multiple cell divisions, with abnormal septation A phenotype in which a spore germinates to produce a cell of normal morphology (i.e. size, shape, and structure) that undergoes two or more rounds of cell division in which septum assembly is abnormal, and then dies. FYPO_relaxed.owl FYPO:0001113 biolink:NamedThing normal cellular response to pheromone A cellular response phenotype in which the cellular response to a pheromone is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001114 biolink:NamedThing normal cellular response to M-factor A cellular response phenotype in which the cellular response to M-factor is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001115 biolink:NamedThing normal cellular response to P-factor A cellular response phenotype in which the cellular response to P-factor is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001116 biolink:NamedThing decreased RNA level during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydrogen peroxide is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001280 biolink:NamedThing decreased RNA level during cellular response to oxidative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to oxidative stress is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001152 biolink:NamedThing decreased RNA level during nitrogen starvation A cell phenotype in which the amount of RNA measured in a cell when the cell is subject to nitrogen starvation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001889 biolink:NamedThing RNA absent from cell A cell phenotype in which the amount of RNA measured in a cell is too low to detect. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0002944 biolink:NamedThing decreased RNA level during G0 A cell phenotype in which the amount of RNA measured in a cell is lower than normal when the cell is in G0 phase. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003032 biolink:NamedThing decreased RNA level during glucose starvation A cell phenotype in which the amount of RNA measured in a cell when the cell is subject to glucose starvation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003426 biolink:NamedThing decreased RNA level during cellular response to pheromone A cell phenotype in which the amount of RNA measured in a cell during a cellular response to a pheromone is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004169 biolink:NamedThing decreased RNA level in stationary phase A cell phenotype in which the amount of RNA measured in a cell is lower than normal when the population in which the cell is found is in stationary phase. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004630 biolink:NamedThing decreased RNA level during meiotic cell cycle A cell phenotype in which the amount of RNA measured in a cell is lower than normal during the meiotic cell cycle. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0006209 biolink:NamedThing decreased RNA level during cellular response to copper ion starvation A cell phenotype in which the amount of RNA measured in a cell during a cellular response to copper ion starvation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001130 biolink:NamedThing increased protein localization to nucleus during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased. FYPO_relaxed.owl FYPO:0001424 biolink:NamedThing abolished protein localization to nucleus during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished. FYPO_relaxed.owl FYPO:0001514 biolink:NamedThing decreased protein localization to nucleus during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased. FYPO_relaxed.owl FYPO:0002338 biolink:NamedThing abnormal protein localization to nuclear periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is abnormal. The nuclear periphery is the portion of the nuclear lumen proximal to the inner nuclear membrane. FYPO_relaxed.owl FYPO:0002529 biolink:NamedThing abnormal protein localization to nucleoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abnormal. FYPO_relaxed.owl FYPO:0002963 biolink:NamedThing abnormal protein localization to nuclear exosome focus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to nuclear exosome foci is abnormal. Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle, such as Mmi1, Iss10, and Red1. FYPO_relaxed.owl FYPO:0003192 biolink:NamedThing abolished protein localization to nucleus during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished during mitosis. FYPO_relaxed.owl FYPO:0003687 biolink:NamedThing abnormal protein localization to nucleolus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus is abnormal. FYPO_relaxed.owl FYPO:0004334 biolink:NamedThing increased protein localization to nucleus during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0004339 biolink:NamedThing decreased protein localization to nucleus during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0004351 biolink:NamedThing increased protein localization to nucleus during cellular response to methylglyoxal A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased during a cellular response to methylglyoxal. FYPO_relaxed.owl FYPO:0004352 biolink:NamedThing decreased protein localization to nucleus during cellular response to methylglyoxal A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to methylglyoxal. FYPO_relaxed.owl FYPO:0004453 biolink:NamedThing decreased protein localization to nucleus during cellular response to calcium ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to calcium ions. FYPO_relaxed.owl FYPO:0004753 biolink:NamedThing abolished protein localization to nucleus during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004885 biolink:NamedThing abnormal protein localization to nuclear envelope during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear envelope is abnormal. FYPO_relaxed.owl FYPO:0005338 biolink:NamedThing decreased protein localization to nucleus during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0005339 biolink:NamedThing increased protein localization to nucleus during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0005672 biolink:NamedThing decreased protein localization to nucleus during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during mitosis. FYPO_relaxed.owl FYPO:0006743 biolink:NamedThing decreased protein localization to nucleus during cellular response to osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to osmotic stress. FYPO_relaxed.owl FYPO:0006744 biolink:NamedThing decreased protein localization to nucleus during cellular response to tschimganine A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to tschimganine. FYPO_relaxed.owl FYPO:0007497 biolink:NamedThing aggregated nuclear exosome foci A cell phenotype observed in the vegetative growth phase of the life cycle in which fewer, larger nuclear exosome foci are present than normal. Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle, such as Mmi1, Iss10, and Red1. FYPO_relaxed.owl FYPO:0007545 biolink:NamedThing increased duration of protein localization to mitotic nuclear bridge A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the mitotic nuclear bridge for a longer time than normal. FYPO_relaxed.owl FYPO:0008043 biolink:NamedThing increased protein localization to nucleus during stationary phase A cell phenotype observed in which the localization of a protein to the nucleus is increased during stationary phase. FYPO_relaxed.owl FYPO:0001131 biolink:NamedThing abnormal protein localization to heterochromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin is abnormal. FYPO_relaxed.owl FYPO:0002473 biolink:NamedThing abnormal protein localization to double-strand break site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the region of a chromosome at which a DNA double-strand break has occurred is abnormal. FYPO_relaxed.owl FYPO:0003068 biolink:NamedThing decreased protein localization to chromatin at replication forks during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication forks is decreased during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0003950 biolink:NamedThing decreased protein localization to chromatin at replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins is decreased. FYPO_relaxed.owl FYPO:0004345 biolink:NamedThing decreased protein localization to chromatin at long terminal repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at long terminal repeats is decreased. FYPO_relaxed.owl FYPO:0004346 biolink:NamedThing decreased protein localization to chromatin at ncRNA genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at non-coding RNA genes is decreased. FYPO_relaxed.owl FYPO:0005109 biolink:NamedThing premature protein localization to chromatin at replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins begins earlier than normal. FYPO_relaxed.owl FYPO:0005222 biolink:NamedThing decreased histone H3 localization to chromatin at protein coding gene A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of histone H3 to chromatin at one or more protein-coding genes is decreased. FYPO_relaxed.owl FYPO:0005235 biolink:NamedThing abolished protein localization to chromatin at stalled replication fork A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at stalled replication forks is abolished. FYPO_relaxed.owl FYPO:0005530 biolink:NamedThing abolished protein localization to chromatin at boundary element IRC1L A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the IRC1L boundary element is abolished. FYPO_relaxed.owl FYPO:0005531 biolink:NamedThing decreased protein localization to chromatin at boundary element IRC1L A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the IRC1L boundary element is decreased. FYPO_relaxed.owl FYPO:0005896 biolink:NamedThing decreased protein localization to chromatin during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is decreased during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006032 biolink:NamedThing decreased protein localization to chromatin during mitotic DNA replication A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is decreased during mitotic DNA replication. FYPO_relaxed.owl FYPO:0006321 biolink:NamedThing decreased protein localization to chromatin at stalled replication fork A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at stalled replication forks is decreased. FYPO_relaxed.owl FYPO:0006612 biolink:NamedThing decreased protein localization to chromatin at transcription termination site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is decreased at sequences that cause RNA polymerase to terminate transcription. FYPO_relaxed.owl FYPO:0006734 biolink:NamedThing delayed onset of protein localization to chromatin at replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins begins later than normal. FYPO_relaxed.owl FYPO:0007408 biolink:NamedThing abnormal protein localization to chromatin at polyadenylation site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is abnormal at sites encoding polyadenylation signals. FYPO_relaxed.owl FYPO:0007465 biolink:NamedThing altered spatial extent of protein localization to chromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein localizes to chromatin over a different spatial extent than normal. The protein may localize to a larger or smaller region than normal, or its localization may be shifted along the length of the chromosome. FYPO_relaxed.owl FYPO:0007505 biolink:NamedThing decreased protein localization to chromatin at promoter A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more specific promoter elements is decreased. FYPO_relaxed.owl FYPO:0001132 biolink:NamedThing abolished protein localization to heterochromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin is abolished. FYPO_relaxed.owl FYPO:0002385 biolink:NamedThing decreased protein localization to heterochromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin is decreased. FYPO_relaxed.owl FYPO:0003010 biolink:NamedThing increased protein localization to subtelomeric heterochromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin in subtelomeric regions is increased. FYPO_relaxed.owl FYPO:0004237 biolink:NamedThing increased protein localization to heterochromatin at centromere outer repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at centromere outer repeat regions of a chromosome is decreased. FYPO_relaxed.owl FYPO:0004377 biolink:NamedThing increased protein localization to heterochromatin at silent mating-type cassette A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at the silenced mating-type cassettes is increased. FYPO_relaxed.owl FYPO:0003744 biolink:NamedThing abolished protein localization to centromeric chromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is abolished. FYPO_relaxed.owl FYPO:0004312 biolink:NamedThing abolished protein localization to CENP-A containing chromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to CENP-A containing chromatin is abolished. FYPO_relaxed.owl FYPO:0005095 biolink:NamedThing abolished protein localization to chromatin at replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins is abolished. FYPO_relaxed.owl FYPO:0006349 biolink:NamedThing abolished protein localization to chromatin at promoter A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more specific promoter elements is abolished. FYPO_relaxed.owl FYPO:0007214 biolink:NamedThing abolished protein localization to chromatin at heterochromatin island A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more heterochromatin islands is abolished. FYPO_relaxed.owl FYPO:0007215 biolink:NamedThing abolished protein localization to chromatin at lncRNA gene A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more lncRNA genes is abolished. FYPO_relaxed.owl FYPO:0001134 biolink:NamedThing normal mature 18S rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 18S ribosomal RNA measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006000 biolink:NamedThing normal rRNA or precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any ribosomal RNA (rRNA) primary transcript, rRNA precursor or processing intermediate, or mature rRNA measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003399 biolink:NamedThing normal 27S rRNA precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 27S ribosomal RNA precursor measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003400 biolink:NamedThing normal 20S rRNA precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 20S ribosomal RNA precursor measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004680 biolink:NamedThing normal polyadenylated 5.8S rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyadenylated 5.8S rRNA measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004682 biolink:NamedThing normal polyadenylated 5S rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyadenylated 5S rRNA measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007012 biolink:NamedThing normal mature 28S rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 28S ribosomal RNA measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007013 biolink:NamedThing normal mature 5S rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5S ribosomal RNA measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007014 biolink:NamedThing normal mature 5.8S rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5.8S ribosomal RNA measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006469 biolink:NamedThing normal mature ncRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature non-coding RNA (ncRNA) measured in a cell is normal (i.e. indistinguishable from wild type). Total ncRNA or a specific ncRNA may be measured. FYPO_relaxed.owl FYPO:0002580 biolink:NamedThing normal mature tRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature transfer RNA (tRNA) measured in a cell is normal (i.e. indistinguishable from wild type). Total tRNA or a specific tRNA may be measured. FYPO_relaxed.owl FYPO:0006996 biolink:NamedThing normal antisense RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of antisense RNA measured in a cell normal (i.e. indistinguishable from wild type). Antisense RNA is transcribed from the coding, rather than the template, strand of DNA. FYPO_relaxed.owl FYPO:0001135 biolink:NamedThing increased 35S rRNA precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the 35S rRNA primary transcript measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003600 biolink:NamedThing increased rRNA precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any rRNA precursor measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001136 biolink:NamedThing increased 27S rRNA precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any 27S rRNA precursor measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0007063 biolink:NamedThing increased 23S rRNA precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any 23S rRNA precursor measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0007064 biolink:NamedThing increased 22S rRNA precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any 22S rRNA precursor measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001137 biolink:NamedThing decreased mature 25S rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the mature 25S rRNA measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001138 biolink:NamedThing decreased mature 5.8S rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the mature 5.8S rRNA measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0003675 biolink:NamedThing increased mature 5.8SL rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the large form of 5.8S rRNA measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003694 biolink:NamedThing decreased mature 18S rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 18S ribosomal RNA measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0005507 biolink:NamedThing increased mature rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature ribosomal RNA (rRNA) measured in a cell is higher than normal. Total rRNA or a specific rRNA may be affected. FYPO_relaxed.owl FYPO:0006468 biolink:NamedThing altered mature rRNA level during vegetative growth A cell phenotype in which the amount of mature ribosomal RNA (rRNA) measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total rRNA or a specific rRNA may be affected. FYPO_relaxed.owl FYPO:0007065 biolink:NamedThing 20S rRNA precursor absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 20S rRNA precursor measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0008091 biolink:NamedThing increased polyadenylated rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature, polyadenylated rRNA measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006470 biolink:NamedThing decreased mature rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature ribosomal RNA (rRNA) measured in a cell is lower than normal. Total rRNA or a specific rRNA may be affected. FYPO_relaxed.owl FYPO:0002990 biolink:NamedThing increased leucine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of leucine into the cell occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0001141 biolink:NamedThing abolished transcriptional response to pheromone A conjugation phenotype in which regulation of transcription in response to mating pheromone is abolished. FYPO_relaxed.owl FYPO:0003770 biolink:NamedThing decreased transcriptional response to pheromone A transcription regulation phenotype in which pheromone-responsive positive regulation of transcription from an RNA polymerase II promoter is decreased. FYPO_relaxed.owl FYPO:0004581 biolink:NamedThing increased transcriptional response to pheromone A transcription regulation phenotype in which pheromone-responsive positive regulation of transcription from an RNA polymerase II promoter is increased. FYPO_relaxed.owl FYPO:0001144 biolink:NamedThing decreased Man8GlcNAc level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man8GlcNAc2 measured in a cell is lower than normal. Man8GlcNAc2 is any N-glycan that consists of a branched ten-membered mannooligosaccharide containing eight D-mannosyl residues and two N-acetylglucosamine residues. FYPO_relaxed.owl FYPO:0001195 biolink:NamedThing decreased galactomannan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0001209 biolink:NamedThing polysaccharide absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a polysaccharide measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0001212 biolink:NamedThing decreased Glc1Man9GlcNAc level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Glc1Man9GlcNAc2 measured in a cell is lower than normal. Glc1Man9GlcNAc2 is an N-glycan that is involved in post-translational modification of proteins, and consists of a branched ten-membered mannooligosaccharide containing one D-glucose residue, nine D-mannosyl residues and two N-acetylglucosamine residues. FYPO_relaxed.owl FYPO:0001145 biolink:NamedThing increased Man9GlcNAc level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man9GlcNAc2 measured in a cell is higher than normal. Man9GlcNAc2 is any N-glycan that consists of a branched undecasaccharide consisting of nine D-mannosyl residues and two N-acetylglucosamine residues. FYPO_relaxed.owl FYPO:0001194 biolink:NamedThing increased beta-glucan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of beta-D-glucan measured in the cell is greater than normal. FYPO_relaxed.owl FYPO:0001213 biolink:NamedThing increased Man8GlcNAc level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Man8GlcNAc2 measured in a cell is higher than normal. Man8GlcNAc2 is any N-glycan that consists of a branched ten-membered mannooligosaccharide containing eight D-mannosyl residues and two N-acetylglucosamine residues. FYPO_relaxed.owl FYPO:0005754 biolink:NamedThing increased (1->3)-alpha-D-glucan level in periplasmic space A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of (1->3)-alpha-D-glucan measured in the periplasmic space is greater than normal. FYPO_relaxed.owl FYPO:0006980 biolink:NamedThing increased Glc3Man9GlcNAc level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Glc3Man9GlcNAc measured in a cell is higher than normal. Glc3Man9GlcNAc2 is an N-glycan that is involved in post-translational modification of proteins, and consists of a branched ten-membered mannooligosaccharide containing three D-glucose residues, nine D-mannosyl residues and two N-acetylglucosamine residues. FYPO_relaxed.owl FYPO:0001146 biolink:NamedThing decreased misfolded glycoprotein degradation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of misfolded glycoprotein degradation is decreased. FYPO_relaxed.owl FYPO:0004545 biolink:NamedThing decreased proteasomal ubiquitin-dependent protein degradation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of proteasome-mediated, ubiquitin-dependent protein degradation is decreased. FYPO_relaxed.owl FYPO:0003300 biolink:NamedThing decreased protein degradation via N-end rule pathway during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of ubiquitin-dependent protein degradation via the N-end rule pathway is decreased. FYPO_relaxed.owl FYPO:0003585 biolink:NamedThing decreased anaphase-promoting complex-dependent protein catabolic process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of ubiquitin-dependent protein degradation with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome, is decreased. FYPO_relaxed.owl FYPO:0001160 biolink:NamedThing cell cycle arrest at mitotic G2/M phase transition during stationary phase A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0001799 biolink:NamedThing cell cycle arrest at mitotic G2/M phase transition during response to DNA damage A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0003825 biolink:NamedThing inviable binucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition before cell separation A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable and has two nuclei but no septum, and the mitotic cell cycle is arrested with nuclei at the mitotic G2/M phase transition. FYPO_relaxed.owl FYPO:0007185 biolink:NamedThing abnormal cell cycle arrest at mitotic G2/M phase transition during cellular response to hydroxyurea A cellular process phenotype in which progression through the mitotic cell cycle is abnormally arrested at the mitotic G2/M phase transition during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0007510 biolink:NamedThing cell cycle arrest at mitotic G2/M phase transition in absence of mitotic DNA replication checkpoint A cellular process phenotype in which progression through the mitotic cell cycle is abnormally arrested at the mitotic G2/M phase transition in the absence of the mitotic DNA replication checkpoint. The previous S phase is completed, no replication intermediates can be observed, and cells do not undergo rereplication. FYPO_relaxed.owl FYPO:0007702 biolink:NamedThing inviable elongated cell with cell cycle arrest at mitotic G2/M phase transition A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is longer than normal, and the mitotic cell cycle is arrested with nuclei at the mitotic G2/M phase transition. FYPO_relaxed.owl FYPO:0001839 biolink:NamedThing normal minichromosome loss A cell phenotype in which minichromosomes are lost at the same frequency as in wild-type cells. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation. FYPO_relaxed.owl FYPO:0005582 biolink:NamedThing normal monoacylglycerol phosphate chain length A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains monoacylglycerol phosphates (also called lysophospholipids) that have normal length fatty acid chain residues. FYPO_relaxed.owl FYPO:0005622 biolink:NamedThing normal topoisomerase-DNA adduct level A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains a normal (i.e. indistinguishable from wild type) amount of adducts formed between a topoisomerase and DNA. FYPO_relaxed.owl FYPO:0007249 biolink:NamedThing normal level of X-shaped replication intermediates A cell phenotype in which the level of X-shaped DNA replication intermediates is normal (i.e. indistinguishable from wild type). X-shaped intermediates may be formed by replication forks moving bidirectionally from outside the region, or by the increased formation or persistence of Holliday junctions or similar recombination intermediates. FYPO_relaxed.owl FYPO:0008175 biolink:NamedThing normal oxygen consumption A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the amount of oxygen consumed by cells in a given time is normal. FYPO_relaxed.owl FYPO:0001170 biolink:NamedThing decreased methionine import during nitrogen starvation A cellular process phenotype in which the import of methionine into the cell occurs to a lower extent than normal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0001558 biolink:NamedThing decreased methionine import A cellular process phenotype in which the import of methionine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001554 biolink:NamedThing abnormal tRNA processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA processing is abnormal. tRNA processing is the conversion a primary tRNA transcript into a mature tRNA molecules. FYPO_relaxed.owl FYPO:0003676 biolink:NamedThing abnormal 5S RNA maturation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule is abnormal. FYPO_relaxed.owl FYPO:0003683 biolink:NamedThing abnormal spliceosomal complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which any process of spliceosomal complex assembly is abnormal. FYPO_relaxed.owl FYPO:0003722 biolink:NamedThing decreased tRNA 5'-leader removal A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the removal of leader sequences to generate the mature 5'-end of a tRNA occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004492 biolink:NamedThing abnormal RNA 5'-end processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 5' end of an RNA molecule is abnormal. FYPO_relaxed.owl FYPO:0004956 biolink:NamedThing abnormal mitochondrial RNA 3'-end processing A cell phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial RNA 3'-end processing is abnormal. FYPO_relaxed.owl FYPO:0006070 biolink:NamedThing increased small RNA 3' adenylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more adenylyl residues to the 3' end of a small RNA (sRNA) molecule occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006071 biolink:NamedThing decreased small RNA 3' adenylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more adenylyl residues to the 3' end of a small RNA (sRNA) molecule occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006072 biolink:NamedThing abolished small RNA 3' uridylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the addition of one or more uridylyl residues to the 3' end of a small RNA (sRNA) molecule does not occur. FYPO_relaxed.owl FYPO:0007918 biolink:NamedThing abnormal RNA 3'-end processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA 3' end processing is abnormal. FYPO_relaxed.owl FYPO:0007919 biolink:NamedThing abnormal RNA alternative polyadenylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which alternative polyadenylation of RNA is abnormal. RNA alternative polyadenylation generates RNA molecules with variable 3'-end lengths from a given RNA by differential use of cleavage and polyadenylation signals. Includes differences in the relative usage levels of alternative polyadenylation sites. FYPO_relaxed.owl FYPO:0001173 biolink:NamedThing abolished 7-methylguanosine cap hypermethylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to form a 2,2,7-trimethylguanosine cap structure is abolished. FYPO_relaxed.owl FYPO:0001768 biolink:NamedThing abolished tRNA-Asp C38 methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of methyl groups to the C38 residue in a tRNA-Asp molecule is abolished. FYPO_relaxed.owl FYPO:0003218 biolink:NamedThing abolished tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the modification of a wobble base uridine residue in a tRNA to 5-methoxycarbonylmethyl-2-thiouridine is abolished. FYPO_relaxed.owl FYPO:0003621 biolink:NamedThing abolished U6 2'-O-snRNA methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which posttranscriptional addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule is abolished. FYPO_relaxed.owl FYPO:0003957 biolink:NamedThing abolished tRNA guanosine N2,N2-dimethylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of two methyl groups to the N2 position of a guanine residue in a tRNA molecule is abolished. Normally, two methyl groups are transferred to the G26 residue. FYPO_relaxed.owl FYPO:0005177 biolink:NamedThing abolished tRNA wobble position uridine thiolation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the modification of a wobble base uridine residue in a tRNA to 2-thiouridine is abolished. FYPO_relaxed.owl FYPO:0001178 biolink:NamedThing loss of viability upon nitrogen starvation A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells in a culture in stationary phase are deprived of nitrogen. FYPO_relaxed.owl FYPO:0004162 biolink:NamedThing loss of viability upon glucose starvation A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells the population are subject to glucose starvation. FYPO_relaxed.owl FYPO:0007088 biolink:NamedThing loss of viability upon sulfur starvation A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells the population are subject to sulfur starvation. FYPO_relaxed.owl FYPO:0007119 biolink:NamedThing loss of viability upon amino acid starvation A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells the population are subject to starvation for one or more amino acids. FYPO_relaxed.owl FYPO:0007792 biolink:NamedThing loss of viability upon magnesium starvation A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells the population are subject to magnesium starvation. FYPO_relaxed.owl FYPO:0004374 biolink:NamedThing abolished protein localization to cytoplasm during glucose starvation A cell phenotype in which the localization of a protein to the cytoplasm is abolished when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0005208 biolink:NamedThing abolished protein localization during meiotic cell cycle A cell phenotype in which a protein does not localize to, and is therefore absent from, a place where it is normally found during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0007703 biolink:NamedThing abolished protein localization to lateral cell cortex during glucose starvation A cell phenotype in which the localization of a protein to the cell cortex does not occur when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0007864 biolink:NamedThing abolished protein localization to meiotic spindle pole during meiosis I A cell phenotype in which the localization of a protein to one or both poles of the meiotic spindle does not occur during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0008004 biolink:NamedThing abolished protein localization to site of mechanical stress A cell phenotype in which a protein does not localize to, and is therefore absent from, a site of mechanical stress on the cell surface where it is normally found. FYPO_relaxed.owl FYPO:0001181 biolink:NamedThing normal maltase activity A molecular function phenotype in which the observed rate of maltose alpha-glucosidase (also known as maltase) activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001185 biolink:NamedThing decreased alpha-glucosidase activity A molecular function phenotype in which the observed rate of an alpha-glucosidase activity is decreased. FYPO_relaxed.owl FYPO:0007796 biolink:NamedThing abnormal glucan 1,3-alpha-glucosidase activity A molecular function phenotype in which the observed rate of glucan 1,3-alpha-glucosidase activity is abnormal. FYPO_relaxed.owl FYPO:0001186 biolink:NamedThing decreased maltase activity A molecular function phenotype in which the observed rate of maltose alpha-glucosidase (also known as maltase) activity is decreased. FYPO_relaxed.owl FYPO:0001206 biolink:NamedThing abolished maltase activity A molecular function phenotype in which maltase activity is absent. FYPO_relaxed.owl FYPO:0001463 biolink:NamedThing abnormal immediate intracellular calcium spike following extracellular calcium stimulus A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases abnormally, or does not change, immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a "burst" within one minute, and then decreases to a new steady-state concentration. FYPO_relaxed.owl FYPO:0001468 biolink:NamedThing abnormal steady-state intracellular calcium level following extracellular calcium stimulus A cell phenotype observed in the vegetative growth phase of the life cycle in which the steady-state intracellular calcium ion (Ca2+) concentration increases abnormally, or does not change, following an extracellular Ca2+ stimulus. Normally, a dose-dependent increased steady-state Ca2+ concentration is reached within 2-3 minutes of extracellular Ca2+ addition, and is sustained for several hours. FYPO_relaxed.owl FYPO:0008063 biolink:NamedThing decreased immediate intracellular calcium spike following osmotic shock A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases abnormally, or does not change, immediately following osmotic shock. Normally, the intracellular Ca2+ concentration increases to a peak in a "burst" within one minute, and then decreases to a new steady-state concentration. FYPO_relaxed.owl FYPO:0001200 biolink:NamedThing abnormal cellular response to calcium starvation A stress response phenotype observed in the vegetative growth phase of the life cycle in which the response to calcium starvation is abnormal. FYPO_relaxed.owl FYPO:0001906 biolink:NamedThing abnormal cellular response to thiamine starvation A stress response phenotype observed in the vegetative growth phase of the life cycle in which the response to thiamine starvation is abnormal. FYPO_relaxed.owl FYPO:0001203 biolink:NamedThing coflocculating cells A cell population phenotype that reflects increased occurrence of coflocculation. In coflocculation, yeast cells coaggregate with cells of another species, usually bacteria. FYPO_relaxed.owl FYPO:0003335 biolink:NamedThing increased galactose-specific flocculation A cell population phenotype that reflects increased occurrence of galactose-specific flocculation. Galactose-specific flocculation is the non-sexual aggregation of single cells, mediated by the binding of cell wall proteins on one cell to galactose residues on the other. FYPO_relaxed.owl FYPO:0004153 biolink:NamedThing increased flocculation in stationary phase A cell population phenotype that reflects increased occurrence of flocculation when the population is in stationary phase. Flocculation is the non-sexual aggregation of single cells. FYPO_relaxed.owl FYPO:0009111 biolink:NamedThing increased flocculation during vegetative growth A vegetative cell population phenotype that reflects increased occurrence of flocculation. Flocculation is the non-sexual aggregation of single cells. FYPO_relaxed.owl FYPO:0001983 biolink:NamedThing protein absent from cell A cell phenotype in which the amount of protein measured in a cell is too low to detect. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003511 biolink:NamedThing L-ergothioneine absent from cell A cell phenotype in which the amount of L-ergothioneine measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0003512 biolink:NamedThing hercynine absent from cell A cell phenotype in which the amount of hercynine (N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine) measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0003513 biolink:NamedThing hercynylcysteine sulfoxide absent from cell A cell phenotype in which the amount of hercynylcysteine sulfoxide measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0003514 biolink:NamedThing hercynylselenocysteine absent from cell A cell phenotype in which the amount of hercynylselenocysteine measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0003515 biolink:NamedThing L-selenoneine absent from cell A cell phenotype in which the amount of L-selenoneine measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0008142 biolink:NamedThing heme absent from cell A cell phenotype in which the amount heme measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0001284 biolink:NamedThing phosphatidylserine absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylserine measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0001712 biolink:NamedThing coenzyme Q10 absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of coenzyme Q10 measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0001723 biolink:NamedThing ferrichrome absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more ferrichromes measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0002123 biolink:NamedThing pyruvylated galactose absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 4,6-pyruvylated D-galactose (4,6-O-[(1R)-1-carboxyethylidene]-D-galactose) measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0002313 biolink:NamedThing ergosterol absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ergosterol measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0002314 biolink:NamedThing GGPP absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of all-trans-geranylgeranyl diphosphate (GGPP) measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0002676 biolink:NamedThing dTTP absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dTTP measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0002722 biolink:NamedThing phytochelatin absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phytochelatin measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0003159 biolink:NamedThing cAMP absent from cell A cell phenotype in which the amount of cyclic AMP (cAMP) measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0003161 biolink:NamedThing RNA absent from cell during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003693 biolink:NamedThing sulfide absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of (S2-, also called acid labile sulfide) measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0003881 biolink:NamedThing mtDNA absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mitochondrial DNA measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0005881 biolink:NamedThing ophthalmic acid absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ophthalmic acid measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0006974 biolink:NamedThing triglyceride absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more triglycerides measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0007820 biolink:NamedThing polyphosphate absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyphosphate measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0007934 biolink:NamedThing dihydrouridine absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dihydrouridine measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0008262 biolink:NamedThing mannosylinositol phosphorylceramide absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mannosylinositol phosphorylceramide measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0001210 biolink:NamedThing Glc2Man9GlcNAc absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Glc2Man9GlcNAc2 measured in a cell is too low to detect. Glc2Man9GlcNAc2 is an N-glycan that is involved in post-translational modification of proteins, and consists of a branched ten-membered mannooligosaccharide containing two D-glucose residues, nine D-mannosyl residues and two N-acetylglucosamine residues. FYPO_relaxed.owl FYPO:0001211 biolink:NamedThing Glc3Man9GlcNAc absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of Glc3Man9GlcNAc measured in a cell is too low to detect. Glc3Man9GlcNAc2 is an N-glycan that is involved in post-translational modification of proteins, and consists of a branched ten-membered mannooligosaccharide containing three D-glucose residues, nine D-mannosyl residues and two N-acetylglucosamine residues. FYPO_relaxed.owl FYPO:0006840 biolink:NamedThing normal LinE complex assembly A cellular process phenotype in which LinE complex assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007147 biolink:NamedThing normal Mei2 nuclear dot formation A cellular process phenotype in which Mei2 nuclear dot formation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007356 biolink:NamedThing normal Smp focus formation A cellular process phenotype in which Smp focus formation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008073 biolink:NamedThing normal RITS complex assembly A cellular process phenotype in which the assembly of a RITS complex in the vegetative growth phase of the life cycle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001218 biolink:NamedThing abolished nuclear export during cellular response to nitrogen starvation A cellular process phenotype in which nuclear export does not occur when the cell is subject to nitrogen starvation. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected. FYPO_relaxed.owl FYPO:0001267 biolink:NamedThing abolished nuclear export during cellular hypotonic salinity response A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear export does not occur when the cell is subject to a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment. Nuclear export is the directed movement of any substance out of the nucleus; export of all substances or a specific substance may be affected. FYPO_relaxed.owl FYPO:0001921 biolink:NamedThing abolished protein export from nucleus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein export from the nucleus does not occur. Export of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001219 biolink:NamedThing increased protein level during cellular response to nitrogen starvation A cell phenotype in which the amount of protein measured in a cell during a cellular response to nitrogen starvation is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001220 biolink:NamedThing increased protein level during cellular response to pheromone A cell phenotype in which the amount of protein measured in a cell during a cellular response to a pheromone is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003611 biolink:NamedThing increased protein level during meiosis A cell phenotype in which the amount of protein measured in a cell during one or both meiotic nuclear divisions is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003866 biolink:NamedThing increased protein level during G0 A cell phenotype in which the amount of protein measured in a cell when the cell is in G0 phase is higher than normal. Total protein or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003914 biolink:NamedThing increased protein level in stationary phase A cell phenotype in which the amount of protein measured in a cell is higher than normal when the population in which the cell is found is in stationary phase. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001223 biolink:NamedThing binucleate multiseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and more than one septum. FYPO_relaxed.owl FYPO:0002156 biolink:NamedThing binucleate monoseptate cell, with angled septum A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two nuclei and one septum, and in which the septum is located between the two nuclei but is not perpendicular to the long axis of the cell. FYPO_relaxed.owl FYPO:0004047 biolink:NamedThing binucleate vegetative cell with fragmented septum A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains two nuclei and pieces of a septum that does not completely bisect the cell. FYPO_relaxed.owl FYPO:0006198 biolink:NamedThing inviable binucleate vegetative cell, with normal cell length and increased cell diameter A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, has two nuclei, and has normal length but a greater diameter than normal. FYPO_relaxed.owl FYPO:0006262 biolink:NamedThing inviable stubby binucleate vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable and has two nuclei, and the cell diameter is larger than normal and the cell length is shorter than normal. FYPO_relaxed.owl FYPO:0001254 biolink:NamedThing multinucleate multiseptate vegetative cell, septa grouped A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two or more nuclei and more than one septum, and the septa are grouped together between two compartments, one or more of which may contain multiple nuclei. FYPO_relaxed.owl FYPO:0006023 biolink:NamedThing elongated multinucleate multiseptate vegetative cell, irregular septum position A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated, has two or more nuclei and more than one septum, and the septa are neither grouped together nor all placed with each septum forming a compartment with a single nucleus. Septa may be present singly or in pairs, and in any location relative to the nuclei. FYPO_relaxed.owl FYPO:0007541 biolink:NamedThing viable branched, swollen, elongated, multinucleate, multiseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, branched, has more than one nucleus and more than one septum, and has a larger volume and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0001226 biolink:NamedThing inviable mononucleate vegetative cell with mislocalized septum and anucleate compartment A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, and contains a single nucleus and an asymmetrically located septum. The septum divides the cell into two compartments, one of which contains the nucleus. FYPO_relaxed.owl FYPO:0002303 biolink:NamedThing inviable mononucleate monoseptate vegetative cell with anucleate compartment A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, and has one nucleus and one septum. The septum divides the cell into two compartments, one of which contains the nucleus. FYPO_relaxed.owl FYPO:0002103 biolink:NamedThing inviable swollen mononucleate monoseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has one nucleus and one septum, and is swollen and inviable. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0007670 biolink:NamedThing inviable mononucleate monoseptate vegetative cell with anucleate compartment and normal cell length A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is normal length, and has one nucleus and one septum. The septum divides the cell into two compartments, one of which contains the nucleus. FYPO_relaxed.owl FYPO:0007652 biolink:NamedThing mononucleate vegetative cell with mislocalized septum and anucleate compartment A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell contains a single nucleus and an asymmetrically located septum. The septum divides the cell into two compartments, one of which contains the nucleus. FYPO_relaxed.owl FYPO:0001227 biolink:NamedThing protein mislocalized to cytoplasm during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the cytoplasm is observed there, during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0002714 biolink:NamedThing protein mislocalized to Golgi apparatus A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the Golgi apparatus is observed there. FYPO_relaxed.owl FYPO:0002779 biolink:NamedThing abolished protein localization to nucleus, with protein mislocalized to cytoplasm, during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished, and the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0003390 biolink:NamedThing protein mislocalized to medial cortex during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the medial cortex is observed there. FYPO_relaxed.owl FYPO:0003657 biolink:NamedThing protein mislocalized to endoplasmic reticulum during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the endoplasmic reticulum is observed there. FYPO_relaxed.owl FYPO:0004056 biolink:NamedThing decreased protein localization to nucleus, with protein mislocalized to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased, and some of the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0004478 biolink:NamedThing protein mislocalized to mitochondrion A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the mitochondrion is observed there. FYPO_relaxed.owl FYPO:0004730 biolink:NamedThing protein mislocalized to lateral cell cortex A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the lateral cell cortex is observed there. The lateral cell cortex is the region directly beneath the plasma membrane of the lateral portion of the cell. FYPO_relaxed.owl FYPO:0004780 biolink:NamedThing decreased protein localization to plasma membrane, with protein mislocalized to cytoplasm, during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is decreased, and some of the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0005501 biolink:NamedThing abolished protein localization to cell cortex, with protein mislocalized to cytoplasm, during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is abolished, and the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0005514 biolink:NamedThing protein mislocalized to vacuole A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the vacuole is observed there. FYPO_relaxed.owl FYPO:0006028 biolink:NamedThing decreased protein localization to actin cortical patch, with protein mislocalized to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is decreased, and some of the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0006221 biolink:NamedThing decreased protein localization to cell division site, with protein mislocalized to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division is decreased, and some of the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0006796 biolink:NamedThing abolished protein localization to actin cortical patch, with protein mislocalized to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is abolished, and some of the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0006873 biolink:NamedThing protein mislocalized to cell cortex of cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the cell cortex at one or both cell tips is observed there. FYPO_relaxed.owl FYPO:0007449 biolink:NamedThing abolished protein localization to endoplasmic reticulum, with protein mislocalized to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is abolished, and some of the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0007589 biolink:NamedThing protein mislocalized to endosome A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in endosomes is observed there. FYPO_relaxed.owl FYPO:0001228 biolink:NamedThing increased nuclear protein level during cellular response to hydrogen peroxide A cell phenotype observed in vegetative growth phase of the life cycle, in which the amount of protein measured in the cell nucleus is higher than normal during a cellular response to hydrogen peroxide. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001230 biolink:NamedThing abnormal cell cortex morphology during nitrogen starvation A physical cellular phenotype in which the size, shape, or structure of all or part of the cell cortex is abnormal when the cell is subject to nitrogen starvation. The cell cortex is the region of a cell that lies just beneath the plasma membrane. FYPO_relaxed.owl FYPO:0001231 biolink:NamedThing normal cell cortex morphology A physical cellular phenotype in which the size, shape, and structure of the cell cortex is normal (i.e. indistinguishable from wild type). The cell cortex is the region of a cell that lies just beneath the plasma membrane. FYPO_relaxed.owl FYPO:0001673 biolink:NamedThing normal nuclear morphology A physical cellular phenotype in which the size, shape, or structure of the nucleus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002070 biolink:NamedThing normal nucleus location A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a nucleus in the normal location at the midpoint of the long axis of the cell. FYPO_relaxed.owl FYPO:0002253 biolink:NamedThing normal septum location A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a septum in the normal location at the midpoint of the long axis of the cell. FYPO_relaxed.owl FYPO:0002525 biolink:NamedThing normal chromosome morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of one or more chromosomes are normal. FYPO_relaxed.owl FYPO:0002715 biolink:NamedThing normal Golgi apparatus morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure the Golgi apparatus is normal. FYPO_relaxed.owl FYPO:0003904 biolink:NamedThing normal plasma membrane morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the plasma membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004568 biolink:NamedThing normal spindle A physical cellular phenotype in which the presence, distribution, or morphology of the mitotic or meiotic spindle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004602 biolink:NamedThing normal linear element morphology A physical cellular phenotype in which the size, shape, or structure of all or part of the linear element is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005379 biolink:NamedThing normal spindle pole body A physical cellular phenotype in which the spindle pole bodies are normal (i.e. indistinguishable from wild type) with respect to structure, composition, location, and orientation. FYPO_relaxed.owl FYPO:0006034 biolink:NamedThing normal mitochondrion A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, morphology, or other physical characteristic of the mitochondrion is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006193 biolink:NamedThing normal shmoo morphology A physical cellular phenotype in which the size, shape, or structure of the mating projection is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006512 biolink:NamedThing normal telomere morphology A physical cellular phenotype in which the size, shape, or structure of the telomere is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007114 biolink:NamedThing normal microtubule bundle A physical cellular phenotype in which the amount, distribution, and morphology of microtubule bundles are normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007809 biolink:NamedThing normal cytoplasmic microtubules A physical cellular phenotype in which the amount, distribution, and morphology of cytoplasmic microtubules is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001232 biolink:NamedThing normal cell cortex morphology during nitrogen starvation A physical cellular phenotype in which the size, shape, and structure of the cell cortex are normal when the cell is subject to nitrogen starvation. The cell cortex is the region of a cell that lies just beneath the plasma membrane. FYPO_relaxed.owl FYPO:0007171 biolink:NamedThing normal cell cortex morphology during meiotic prophase I A physical cellular phenotype in which the size, shape, and structure of the cell cortex are normal during prophase of the first meiotic nuclear division. The cell cortex is the region of a cell that lies just beneath the plasma membrane. FYPO_relaxed.owl FYPO:0001244 biolink:NamedThing decreased RNA level during cellular response to thiamine starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to thiamine starvation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001259 biolink:NamedThing decreased RNA level during cellular response to hypoxia A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hypoxia is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001546 biolink:NamedThing decreased RNA level during cellular response to zinc ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to zinc ion is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001684 biolink:NamedThing decreased RNA level during cellular response to purvalanol A A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to purvalanol A is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002042 biolink:NamedThing decreased RNA level during cellular response to iron ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to iron ion starvation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002286 biolink:NamedThing decreased RNA level during cellular response to osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to osmotic stress is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002287 biolink:NamedThing decreased RNA level during cellular response to heat A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to heat is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002623 biolink:NamedThing decreased RNA level during cellular response to glucose stimulus A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to a glucose stimulus is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002937 biolink:NamedThing decreased pre-mRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any unspliced or incompletely spliced mRNA precursor measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0002975 biolink:NamedThing decreased RNA level during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydroxyurea is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003034 biolink:NamedThing decreased RNA level during cellular response to UV A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to ultraviolet light is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003103 biolink:NamedThing decreased mRNA-derived small RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from mRNA transcripts measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0003142 biolink:NamedThing decreased RNA level during cellular response to methyl methanesulfonate A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to methyl methanesulfonate is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003236 biolink:NamedThing decreased transposable element-derived small RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from transposable element transcripts measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0003280 biolink:NamedThing decreased RNA level during cellular response to copper ion starvation during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to copper ion starvation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003377 biolink:NamedThing decreased RNA level during cellular response to nitrosative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to nitrosative stress is lower than normal. Total RNA or a specific RNA may be affected. Nitrosative stress often results from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions. FYPO_relaxed.owl FYPO:0003423 biolink:NamedThing decreased mitochondrial RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mitochondrial RNA measured in a cell is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003601 biolink:NamedThing decreased rRNA precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any rRNA precursor measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0003993 biolink:NamedThing decreased RNA level during cellular response to menadione A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to menadione is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004071 biolink:NamedThing decreased RNA level during cellular response to copper ion during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to copper ions is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004134 biolink:NamedThing decreased RNA level during cellular response to diethyl maleate A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to diethyl maleate is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004192 biolink:NamedThing decreased RNA level during cellular response to ionizing radiation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to ionizing radiation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004349 biolink:NamedThing decreased RNA level during cellular response to methylglyoxal A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to methylglyoxal is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004416 biolink:NamedThing decreased RNA level during cellular response to phosphate starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to phosphate starvation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004477 biolink:NamedThing decreased RNA level during cellular response to calcium ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to calcium ions is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004711 biolink:NamedThing decreased level of translation gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more translation RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Translation RNAs are transcribed from genes whose products are involved in translation. FYPO_relaxed.owl FYPO:0004712 biolink:NamedThing decreased level of nucleotide metabolism gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more nucleotide metabolism RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Nucleotide metabolism RNAs are transcribed from genes whose products are involved in any nucleotide metabolic process. FYPO_relaxed.owl FYPO:0004713 biolink:NamedThing decreased level of amino acid biosynthesis gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more amino acid biosynthesis RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Amino acid biosynthesis RNAs are transcribed from genes whose products are involved in amino acid biosynthetic processes. FYPO_relaxed.owl FYPO:0004714 biolink:NamedThing decreased level of amino acid import gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more amino acid import RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Amino acid import RNAs are transcribed from genes whose products are involved in amino acid import into the cell or an organelle. FYPO_relaxed.owl FYPO:0004878 biolink:NamedThing decreased level of mitotically up-regulated gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more mitotically up-regulated RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). FYPO_relaxed.owl FYPO:0004880 biolink:NamedThing decreased level of lipid metabolism gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more lipid metabolism RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Lipid metabolism RNAs are transcribed from genes whose products are involved in any lipid metabolic process. FYPO_relaxed.owl FYPO:0004897 biolink:NamedThing decreased level of nitrogen starvation gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during nitrogen starvation measured in a cell is lower than normal (i.e. lower than observed in wild-type cells during vegetative growth). FYPO_relaxed.owl FYPO:0004903 biolink:NamedThing decreased level of cell separation after cytokinesis gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cell separation after cytokinesis RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Cell separation after cytokinesis RNAs are transcribed from genes whose products are involved in cell separation after cytokinesis. FYPO_relaxed.owl FYPO:0004905 biolink:NamedThing decreased level of iron homeostasis gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more iron homeostasis RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Iron homeostasis RNAs are transcribed from genes whose products are involved in iron homeostasis. FYPO_relaxed.owl FYPO:0004906 biolink:NamedThing decreased level of histone gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more histone RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Histone RNAs are transcribed from genes encoding histones. FYPO_relaxed.owl FYPO:0004935 biolink:NamedThing decreased RNA level during exit from mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during exit from mitosis is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0005090 biolink:NamedThing decreased level of cytokinesis gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cytokinesis RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Cytokinesis RNAs are transcribed from genes whose products are involved in one or more cytokinetic processes. FYPO_relaxed.owl FYPO:0005187 biolink:NamedThing decreased level of transport gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more transport RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Transport RNAs are transcribed from genes whose products are involved in one or more transport processes. FYPO_relaxed.owl FYPO:0005278 biolink:NamedThing decreased level of glucose-repressed gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more glucose-repressed mRNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Glucose-repressed mRNAs are transcribed from genes whose transcription is negatively regulated when glucose is present. FYPO_relaxed.owl FYPO:0005302 biolink:NamedThing decreased RNA level during mitotic G2 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during the G2 phase of the mitotic cell cycle is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0005654 biolink:NamedThing decreased level of iron assimilation gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more iron assimilation RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Iron assimilation RNAs are transcribed from genes whose products are involved in any process in which iron is solubilized and transported into a cell. FYPO_relaxed.owl FYPO:0005685 biolink:NamedThing decreased RNA level during cellular response to cadmium ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to cadmium ions is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0005826 biolink:NamedThing decreased level of generation of precursor metabolites and energy gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more generation of precursor metabolites and energy RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Generation of precursor metabolites and energy RNAs are transcribed from genes whose products are involved in the formation of precursor metabolites and the liberation of energy from these substances. FYPO_relaxed.owl FYPO:0005908 biolink:NamedThing decreased level of stress responsive gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more messenger RNAs that are normally expressed during a cellular response to stress measured in a cell is lower than normal (i.e. lower than observed in wild-type cells during vegetative growth). FYPO_relaxed.owl FYPO:0005946 biolink:NamedThing decreased level of cell cycle regulated gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more cell cycle-regulated mRNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells). Cell cycle-regulated mRNAs are transcribed from genes whose level of transcription varies depending on cell cycle phase. FYPO_relaxed.owl FYPO:0006334 biolink:NamedThing decreased RNA level during cellular response to zinc ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to zinc ion starvation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0006466 biolink:NamedThing decreased mature ncRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature non-coding RNA (ncRNA) measured in a cell is lower than normal. Total ncRNA or a specific ncRNA may be affected. FYPO_relaxed.owl FYPO:0006748 biolink:NamedThing decreased pre-tRNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more transfer RNA precursor(s) (pre-tRNA) measured in a cell is lower than normal. Total pre-tRNA or a specific pre-tRNA may be affected. FYPO_relaxed.owl FYPO:0006848 biolink:NamedThing decreased total RNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of RNA measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0007084 biolink:NamedThing decreased RNA level during cellular response to sulfur starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to sulfur starvation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0007117 biolink:NamedThing decreased RNA level during cellular response to leucine starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to leucine starvation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0008247 biolink:NamedThing decreased subtelomeric heterochromatin RNA level A cell phenotype in which the amount of RNA derived from subtelomeric heterochromatin regions is lower than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0008248 biolink:NamedThing decreased LTR-derived RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any RNA transcribed from long terminal repeat elements (LTRs) measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0008251 biolink:NamedThing decreased cenH-derived RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from cenH measured in a cell is lower than normal. cenH is a region located between mat2-P and mat3-M that is homologous to centromeric repeats, and that produces non-coding RNAs and small interfering RNAs. FYPO_relaxed.owl FYPO:0001246 biolink:NamedThing normal RNA level during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydrogen peroxide is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0001260 biolink:NamedThing normal RNA level during cellular response to hypoxia A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hypoxia is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001487 biolink:NamedThing normal RNA level during cellular response to heat A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to heat is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001794 biolink:NamedThing normal RNA level during cellular response to purvalanol A A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to purvalanol A is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002146 biolink:NamedThing normal RNA level during cellular response to DEM A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to diethyl maleate (DEM) is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0002984 biolink:NamedThing normal RNA level during cellular response to methyl methanesulfonate A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to methyl methanesulfonate is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003035 biolink:NamedThing normal RNA level during cellular response to UV A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to ultraviolet light is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003620 biolink:NamedThing normal pre-mRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any unspliced or incompletely spliced mRNA precursor measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003772 biolink:NamedThing normal transposon gene mRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of messenger RNA derived from transposon-encoded genes measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003793 biolink:NamedThing normal RNA level during cellular response to osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to osmotic stress is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003992 biolink:NamedThing normal RNA level during cellular response to menadione A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to menadione is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0004350 biolink:NamedThing normal RNA level during cellular response to methylglyoxal A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to methylglyoxal is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0004417 biolink:NamedThing normal RNA level during cellular response to phosphate starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to phosphate starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004579 biolink:NamedThing normal transposable element-derived small RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from transposable element transcripts measured in a cell normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005280 biolink:NamedThing normal level of glucose-repressed gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more glucose-repressed mRNAs measured in a cell is normal (i.e. indistinguishable from wild type). Glucose-repressed mRNAs are transcribed from genes whose transcription is negatively regulated when glucose is present. FYPO_relaxed.owl FYPO:0005602 biolink:NamedThing normal subtelomeric heterochromatin RNA level A cell phenotype in which the amount of RNA derived from subtelomeric heterochromatin forming regions is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0005639 biolink:NamedThing normal RNA level during cellular response to iron ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to iron ion starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0005655 biolink:NamedThing normal level of iron assimilation gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more iron assimilation RNAs measured in a cell is normal (i.e. indistinguishable from wild type). Iron assimilation RNAs are transcribed from genes whose products are involved in any process in which iron is solubilized and transported into a cell. FYPO_relaxed.owl FYPO:0006158 biolink:NamedThing normal RNA level during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during S phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0006202 biolink:NamedThing normal RNA level during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydroxyurea is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0006506 biolink:NamedThing normal RNA level during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during G1 phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0006619 biolink:NamedThing normal nuclear polyadenylated mRNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyadenylated messenger RNA (mRNA) measured in the nucleus is normal (i.e. indistinguishable from wild type). Total mRNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0006829 biolink:NamedThing normal RNA level during cellular response to zinc ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to zinc ion starvation is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0006830 biolink:NamedThing normal RNA level during cellular response to replete zinc A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to replete levels of zinc ion is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0007281 biolink:NamedThing normal level of meiotic gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during meiosis measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008152 biolink:NamedThing normal CUT RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of transcribed cryptic unstable trancripts (CUTs) measured in a cell is normal (i.e. indistinguishable from wild type). Total CUT RNA or a CUT transcribed from a specific locus may be affected. FYPO_relaxed.owl FYPO:0008177 biolink:NamedThing normal centromeric RNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNAs transcribed from the centromere measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008246 biolink:NamedThing normal cenH-derived RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from cenH measured in a cell is normal. cenH is a region located between mat2-P and mat3-M that is homologous to centromeric repeats, and that produces non-coding RNAs and small interfering RNAs. FYPO_relaxed.owl FYPO:0008252 biolink:NamedThing normal LTR-derived RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any RNA transcribed from long terminal repeat elements (LTRs) measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008253 biolink:NamedThing normal telomere repeat region derived RNA level A cell phenotype in which the amount of telomere repeat derived RNA measured in a cell is normal (i.e. indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0001253 biolink:NamedThing elongated multinucleate multiseptate vegetative cell, single septa between nuclei A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is longer than normal, has three or more nuclei and two or more septa, and the septa are not grouped together, but are located so as to form separate compartments with a single nucleus in each. FYPO_relaxed.owl FYPO:0001495 biolink:NamedThing viable elongated multinucleate vegetative cell A cell morphology phenotype in which a vegetative cell is viable, is elongated, and contains more than one nucleus. FYPO_relaxed.owl FYPO:0006165 biolink:NamedThing branched, swollen, elongated, multinucleate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is branched, has more than one nucleus, and has a larger volume and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0006325 biolink:NamedThing elongated multinucleate vegetative cell with multinucleate compartment A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated, may contain a septum, and contains multiple nuclei (usually four or more) per compartment. FYPO_relaxed.owl FYPO:0008045 biolink:NamedThing elongated vegetative cell with more than four nuclei A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more than four nuclei, is longer than normal, and has a greater length:diameter ratio than normal. FYPO_relaxed.owl FYPO:0003344 biolink:NamedThing elongated multinucleate multiseptate cell, single septa between nuclei, during stationary phase A cell morphology phenotype observed when a cell population is in stationary phase in which a cell is elongated, has two or more nuclei and more than one septum, and the septa not grouped together, but are located so as to form separate compartments with a single nucleus in each. FYPO_relaxed.owl FYPO:0001256 biolink:NamedThing increased protein level during cellular response to hypoxia A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hypoxia is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001549 biolink:NamedThing altered protein level during cellular response to hypoxia A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell differs from normal during a cellular response to hypoxia. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001257 biolink:NamedThing normal protein level during cellular response to oxygen A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to the level of oxygen is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0002776 biolink:NamedThing normal level of sumoylated protein in cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of sumoylated protein measured in a cell is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003144 biolink:NamedThing normal protein level during cellular response to methyl methanesulfonate A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to methyl methanesulfonate is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003153 biolink:NamedThing normal protein level during cellular response to heat A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to heat is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003773 biolink:NamedThing normal level of transposon-encoded protein in cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more transposon-encoded proteins measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004006 biolink:NamedThing normal protein level during cellular response to menadione A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to menadione is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004110 biolink:NamedThing normal protein level during exit from mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during exit from mitosis is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004981 biolink:NamedThing normal cellular histone level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more histones measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005074 biolink:NamedThing normal protein level in anaphase-promoting complex A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the anaphase-promoting complex is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005168 biolink:NamedThing normal protein level during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to salt stress is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005227 biolink:NamedThing normal level of ubiquitinated protein in cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ubiquitinated protein measured in a cell is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005320 biolink:NamedThing normal protein level during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during metaphase of mitosis is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005550 biolink:NamedThing normal protein level during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hydroxyurea is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005925 biolink:NamedThing normal protein level during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during mitosis is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005926 biolink:NamedThing normal protein level during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during G1 phase of the mitotic cell cycle is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0006844 biolink:NamedThing normal H2A.Z level at centromere A cell phenotype in which the amount of the histone variant H2A.Z found associated with chromatin in centromeric regions is normal (i.e. indistinguishable from wild type) when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0007054 biolink:NamedThing normal protein level during cellular response to zinc ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to zinc ion starvation is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001258 biolink:NamedThing normal protein level during cellular response to hypoxia A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to hypoxia is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001261 biolink:NamedThing decreased cytokinesis during cellular hyperosmotic response A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitotic cytokinesis is decreased during a cellular hyperosmotic response. FYPO_relaxed.owl FYPO:0001265 biolink:NamedThing increased protein phosphorylation during cellular hyperosmotic response A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular hyperosmotic response. FYPO_relaxed.owl FYPO:0002095 biolink:NamedThing increased protein phosphorylation during cellular response to DNA damage A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to a DNA damage stimulus. FYPO_relaxed.owl FYPO:0002096 biolink:NamedThing increased protein phosphorylation during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0002129 biolink:NamedThing increased protein phosphorylation during cellular response to heat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to heat. FYPO_relaxed.owl FYPO:0002648 biolink:NamedThing increased protein phosphorylation during mitotic prometaphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during prometaphase of mitosis. FYPO_relaxed.owl FYPO:0003077 biolink:NamedThing increased protein autophosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of autophosphorylation of one or more specific proteins, or of specific protein sites, is increased. FYPO_relaxed.owl FYPO:0003692 biolink:NamedThing increased protein phosphorylation during cellular response to oxidative stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to oxidative stress. FYPO_relaxed.owl FYPO:0004112 biolink:NamedThing increased protein phosphorylation during mitotic G2 phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during G2 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004353 biolink:NamedThing increased protein phosphorylation during mitotic S phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004354 biolink:NamedThing increased protein phosphorylation during mitotic G1 phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004355 biolink:NamedThing increased protein phosphorylation during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during mitosis. FYPO_relaxed.owl FYPO:0004949 biolink:NamedThing increased protein phosphorylation during cellular response to rapamycin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to rapamycin. FYPO_relaxed.owl FYPO:0005041 biolink:NamedThing increased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005184 biolink:NamedThing increased phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 5 the C-terminal domain of RNA polymerase II occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005548 biolink:NamedThing increased protein phosphorylation during cellular response to brefeldin A A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to brefeldin A. FYPO_relaxed.owl FYPO:0006498 biolink:NamedThing increased protein phosphorylation during cellular response to UV A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to ultraviolet light. FYPO_relaxed.owl FYPO:0006871 biolink:NamedThing increased protein phosphorylation during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0007526 biolink:NamedThing increased protein phosphorylation during cellular response to salt stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to salt stress. FYPO_relaxed.owl FYPO:0007534 biolink:NamedThing increased phosphorylation of RNA polymerase II C-terminal domain threonine 4 residues during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the threonine residue at position 4 the C-terminal domain of RNA polymerase II occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007907 biolink:NamedThing increased protein phosphorylation during amino acid starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal when a cell is subject to amino acid starvation. FYPO_relaxed.owl FYPO:0001266 biolink:NamedThing normal protein phosphorylation during cellular response to salt stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to salt stress. FYPO_relaxed.owl FYPO:0002290 biolink:NamedThing normal protein phosphorylation during cellular response to osmotic stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal during a cellular response to osmotic stress. FYPO_relaxed.owl FYPO:0001269 biolink:NamedThing abolished protein localization to kinetochore during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is abolished. FYPO_relaxed.owl FYPO:0003074 biolink:NamedThing abolished protein localization to pericentric heterochromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to pericentric heterochromatin is abolished. FYPO_relaxed.owl FYPO:0002902 biolink:NamedThing decreased protein localization to kinetochore during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is decreased. FYPO_relaxed.owl FYPO:0005215 biolink:NamedThing decreased protein localization to kinetochore during mitotic M phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is decreased during mitotic M phase FYPO_relaxed.owl FYPO:0001271 biolink:NamedThing incomplete, unequal mitotic sister chromatid segregation A cellular process phenotype in which mitotic sister chromatid segregation stops before completing separation of chromosomes; some, but not all, DNA may be moved towards the ends of an elongated mitotic spindle. Chromosomes do not segregate into two equal masses. FYPO_relaxed.owl FYPO:0005069 biolink:NamedThing unequal mitotic sister chromatid segregation following normal mitosis A cellular process phenotype in which mitotic sister chromatid segregation fails to separate chromosomes into two equal masses after the cell has undergone a normal mitotic nuclear division and passed through the subsequent mitotic interphase. Unequal mitotic sister chromatid separation may be complete, with two distinct unequal DNA masses located at or near the ends of an elongated mitotic spindle, or incomplete. FYPO_relaxed.owl FYPO:0003758 biolink:NamedThing mitotic spindle elongation without chromosome separation A cellular process phenotype in which mitotic spindle elongation begins, but mitotic sister chromatid segregation stops before completing separation of chromosomes. FYPO_relaxed.owl FYPO:0003970 biolink:NamedThing incomplete mitotic sister chromatid segregation, with chromatin bridge A cellular process phenotype in which mitotic sister chromatid segregation stops before completing separation of chromosomes, and partially separated DNA masses are connected by one or more bridges formed of chromatin. FYPO_relaxed.owl FYPO:0004098 biolink:NamedThing incomplete mitotic sister chromatid segregation, with phi-shaped DNA mass A cellular process phenotype in which mitotic sister chromatid segregation stops before completing separation of chromosomes, and most of the DNA remains in a single mass at or near the midpoint of the mitotic spindle, but portions of the chromosomes can separate along the spindle, resulting in the formation of a DNA mass shaped like the Greek letter phi. FYPO_relaxed.owl FYPO:0001272 biolink:NamedThing incomplete, unequal mitotic sister chromatid segregation, with smeared DNA A cellular process phenotype in which mitotic sister chromatid segregation stops before completing separation of chromosomes, and DNA becomes spread into an indistinct mass along much of the length of the mitotic spindle. FYPO_relaxed.owl FYPO:0001273 biolink:NamedThing mitotic spindle elongation with incomplete, unequal mitotic sister chromatid segregation and unseparated DNA A cellular process phenotype in which mitotic spindle elongation begins, but mitotic sister chromatid segregation stops before completing separation of chromosomes, and DNA remains in a single mass at or near the midpoint of the mitotic spindle. FYPO_relaxed.owl FYPO:0004210 biolink:NamedThing mitotic spindle elongation without chromosome separation with centromeric DNA dissociated from spindle A cellular process phenotype in which mitotic spindle elongation begins, but mitotic sister chromatid segregation stops before completing separation of chromosomes, DNA remains in a single mass at or near the midpoint of the mitotic spindle, and centromeric DNA is not closely associated with the mitotic spindle. FYPO_relaxed.owl FYPO:0004211 biolink:NamedThing mitotic spindle elongation without chromosome separation with centromeric DNA associated with spindle A cellular process phenotype in which mitotic spindle elongation begins, but mitotic sister chromatid segregation stops before completing separation of chromosomes, DNA remains in a single mass at or near the midpoint of the mitotic spindle, and centromeric DNA is closely associated with the mitotic spindle. FYPO_relaxed.owl FYPO:0001275 biolink:NamedThing decreased protein-protein interaction during cellular response to hypoxia A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during a cellular response to hypoxia. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0002656 biolink:NamedThing decreased actin filament binding A molecular function phenotype in which the binding of a protein to one or more actin filaments occurs to a lower extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003206 biolink:NamedThing decreased protein-protein interaction during cellular response to salt stress A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during a cellular response to salt stress. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0003207 biolink:NamedThing decreased protein-protein interaction during cellular response to hydrogen peroxide A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during a cellular response to hydrogen peroxide. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0005293 biolink:NamedThing decreased protein-protein interaction during cellular response to methyl methanesulfonate A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during a cellular response to methyl methanesulfonate. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0005294 biolink:NamedThing decreased protein-protein interaction during cellular response to hydroxyurea A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during a cellular response to hydroxyurea. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0005546 biolink:NamedThing decreased protein-protein interaction during mitotic S phase A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal during S phase of the mitotic cell cycle. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0005784 biolink:NamedThing decreased extent and duration of protein-protein interaction A molecular function phenotype in which the binding of one protein to another occurs to a lower extent, and for a shorter time, than normal. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0006342 biolink:NamedThing decreased microtubule binding A molecular function phenotype in which the binding of a protein to one or more microtubules occurs to a lower extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006451 biolink:NamedThing decreased methylated histone binding A molecular function phenotype in which methylated histone binding by a gene product (usually a protein) in a mutant occurs to a lower extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0008059 biolink:NamedThing decreased K48-linked polyubiquitin binding A molecular function phenotype in which the binding of a protein to K48-linked polyubiquitin occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001276 biolink:NamedThing decreased MCM complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of MCM complex assembly is decreased. FYPO_relaxed.owl FYPO:0001281 biolink:NamedThing normal protein phosphorylation during cellular response to hydrogen peroxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0002099 biolink:NamedThing normal protein phosphorylation during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0002899 biolink:NamedThing normal protein phosphorylation during cellular response to DNA damage A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to a DNA damage stimulus. FYPO_relaxed.owl FYPO:0003076 biolink:NamedThing normal protein autophosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the autophosphorylation of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type). Protein autophosphorylation is the phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. FYPO_relaxed.owl FYPO:0003131 biolink:NamedThing normal protein phosphorylation during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0003214 biolink:NamedThing normal protein phosphorylation during cellular response to glucose starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to glucose starvation. FYPO_relaxed.owl FYPO:0003828 biolink:NamedThing normal ribosomal S6 protein phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the ribosomal small subunit protein S6 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004082 biolink:NamedThing normal protein phosphorylation during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during mitosis. FYPO_relaxed.owl FYPO:0004154 biolink:NamedThing normal protein phosphorylation during cellular response to heat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to heat. FYPO_relaxed.owl FYPO:0004230 biolink:NamedThing normal protein phosphorylation during cellular response to UV A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to ultraviolet light. FYPO_relaxed.owl FYPO:0004327 biolink:NamedThing normal protein phosphorylation during cellular response to sorbitol A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to sorbitol. FYPO_relaxed.owl FYPO:0004450 biolink:NamedThing normal protein phosphorylation during cellular response to calcium ion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to calcium ions. FYPO_relaxed.owl FYPO:0004465 biolink:NamedThing normal protein phosphorylation during cellular response to camptothecin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to camptothecin. FYPO_relaxed.owl FYPO:0005061 biolink:NamedThing normal phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 5 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005395 biolink:NamedThing normal protein phosphorylation during cellular response to methyl methanesulfonate A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0005477 biolink:NamedThing normal protein phosphorylation during cellular response to arsenite ion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to arsenite ions. FYPO_relaxed.owl FYPO:0005614 biolink:NamedThing normal protein phosphorylation during cellular response to bleomycin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to bleomycin. FYPO_relaxed.owl FYPO:0006168 biolink:NamedThing normal protein phosphorylation during cellular response to paraquat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to paraquat. FYPO_relaxed.owl FYPO:0006169 biolink:NamedThing normal protein phosphorylation during cellular response to 4-nitroquinoline N-oxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during a cellular response to 4-nitroquinoline N-oxide. FYPO_relaxed.owl FYPO:0006290 biolink:NamedThing normal protein phosphorylation during mitotic S phase during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during S phase of the mitotic cell cycle and during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0007535 biolink:NamedThing normal phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007539 biolink:NamedThing normal phosphorylation of RNA polymerase II C-terminal domain threonine 4 residues during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the threonine residue at position 4 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007540 biolink:NamedThing normal phosphorylation of RNA polymerase II C-terminal domain tyrosine 1 residues during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the tyrosine residue at position 1 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007761 biolink:NamedThing normal protein phosphorylation during mitotic G2/M transition A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins is normal (i.e. indistinguishable from wild type) during the G2/M phase transition of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0008034 biolink:NamedThing normal phosphorylation of RNA polymerase II C-terminal domain serine 7 residues during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 7 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001282 biolink:NamedThing abnormal chromatin organization during nitrogen starvation A cellular process phenotype in which any process of chromatin organization is abnormal when the cell is subject to nitrogen starvation. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. FYPO_relaxed.owl FYPO:0003871 biolink:NamedThing abnormal chromatin organization during G0 A cellular process phenotype in which any process of chromatin organization is abnormal when the cell is in G0 phase. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. FYPO_relaxed.owl FYPO:0004783 biolink:NamedThing abnormal histone methyltransferase activity A molecular function phenotype in which the observed rate of a histone methyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0006356 biolink:NamedThing abnormal chromatin remodeling A cellular process phenotype in which chromatin remodeling, i.e. any dynamic structural change to chromatin, is abnormal. FYPO_relaxed.owl FYPO:0006620 biolink:NamedThing abnormal chromatin organization during recovery from glucose starvation A cellular process phenotype in which any process of chromatin organization is abnormal when the cell is returned to glucose-rich medium following glucose starvation. FYPO_relaxed.owl FYPO:0001283 biolink:NamedThing decreased protein level during cellular response to nitrogen starvation A cell phenotype in which the amount of protein measured in a cell during a cellular response to nitrogen starvation is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001388 biolink:NamedThing decreased protein level in germinating spore A cell phenotype in which the amount of protein measured in a cell is lower than normal during or just after spore germination. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003865 biolink:NamedThing decreased protein level during G0 A cell phenotype in which the amount of protein measured in a cell is lower than normal when the cell is in G0 phase. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003967 biolink:NamedThing decreased protein level in stationary phase A cell phenotype in which the amount of protein measured in a cell is lover than normal when the population in which the cell is found is in stationary phase. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004991 biolink:NamedThing decreased protein level during meiotic cell cycle A cell phenotype in which the amount of protein measured in a cell during the meiotic cell cycle is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0006541 biolink:NamedThing decreased protein level during mating A cell phenotype in which the amount of protein measured in a cell during mating is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001285 biolink:NamedThing decreased cellular phosphatidylethanolamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylethanolamine measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0002322 biolink:NamedThing decreased cellular FPP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of all-trans-farnesyl diphosphate (FPP) measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0005591 biolink:NamedThing decreased cellular lysophosphatidylcholine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of lysophosphatidylcholine measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0005592 biolink:NamedThing decreased cellular lysophosphatidylethanolamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of lysophosphatidylethanolamine level measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001505 biolink:NamedThing increased cellular phosphatidylserine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylserine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0005586 biolink:NamedThing increased cellular phosphatidylethanolamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylethanolamine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0005587 biolink:NamedThing increased cellular phosphatidic acid level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phosphatidic acid measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0005593 biolink:NamedThing increased cellular inositol phosphorylceramide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of inositol phosphorylceramide measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006134 biolink:NamedThing increased cellular 2-palmitoleoylglycerophosphoinositol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 2-palmitoleoylglycerophosphoinositol measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006137 biolink:NamedThing increased cellular 1-stearoylglycerophosphocholine (18:0) level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 1-stearoylglycerophosphocholine (18:0) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006139 biolink:NamedThing increased cellular 2-myristoylglycerophosphocholine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 2-myristoylglycerophosphocholine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006140 biolink:NamedThing increased cellular 1-eicosenoylglycerophosphocholine (20:1n9) level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 1-eicosenoylglycerophosphocholine (20:1n9) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0007916 biolink:NamedThing increased cellular dihydrosphingosine-1-phosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dihydrosphingosine-1-phosphate (DHS-1P) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001297 biolink:NamedThing abnormal palmitoyl-CoA ligase activity A molecular function phenotype in which the observed rate of palmitoyl-CoA ligase activity is abnormal. FYPO_relaxed.owl FYPO:0001300 biolink:NamedThing abnormal oleoyl-CoA ligase activity A molecular function phenotype in which the observed rate of oleoyl-CoA ligase activity is abnormal. FYPO_relaxed.owl FYPO:0001303 biolink:NamedThing abnormal myristoyl-CoA ligase activity A molecular function phenotype in which the observed rate of myristoyl-CoA ligase activity is abnormal. FYPO_relaxed.owl FYPO:0001298 biolink:NamedThing decreased palmitoyl-CoA ligase activity A molecular function phenotype in which the observed rate of palmitoyl-CoA ligase activity is decreased. FYPO_relaxed.owl FYPO:0001299 biolink:NamedThing abolished palmitoyl-CoA ligase activity A molecular function phenotype in which palmitoyl-CoA ligase activity is absent. FYPO_relaxed.owl FYPO:0001302 biolink:NamedThing decreased oleoyl-CoA ligase activity A molecular function phenotype in which the observed rate of oleoyl-CoA ligase activity is decreased. FYPO_relaxed.owl FYPO:0001304 biolink:NamedThing decreased myristoyl-CoA ligase activity A molecular function phenotype in which the observed rate of myristoyl-CoA ligase activity is decreased. FYPO_relaxed.owl FYPO:0001301 biolink:NamedThing abolished oleoyl-CoA ligase activity A molecular function phenotype in which oleoyl-CoA ligase activity is absent. FYPO_relaxed.owl FYPO:0001550 biolink:NamedThing altered protein level during cellular response to zinc ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell differs from normal during a cellular response to zinc ions. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001982 biolink:NamedThing decreased rate of DNA replication during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA replication is decreased. FYPO_relaxed.owl FYPO:0004599 biolink:NamedThing increased rate of DNA replication during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA replication is increased. FYPO_relaxed.owl FYPO:0005159 biolink:NamedThing decreased DNA synthesis involved in mitotic DNA replication A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the synthesis of DNA that occurs as part of DNA replication is decreased. FYPO_relaxed.owl FYPO:0006240 biolink:NamedThing decreased rate of mitotic DNA replication elongation during cellular response to DNA damage A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA strand elongation involved in mitotic nuclear DNA replication is decreased during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0006242 biolink:NamedThing decreased replication fork stalling during cellular response to DNA damage A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication forks stall at a lower frequency in mutant cells than in wild type during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0006730 biolink:NamedThing abnormal mitotic DNA replication elongation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which strand elongation during nuclear DNA replication is abnormal. FYPO_relaxed.owl FYPO:0006859 biolink:NamedThing decreased mitotic DNA replication at telomere A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of DNA replication is decreased in telomeric regions. FYPO_relaxed.owl FYPO:0006860 biolink:NamedThing decreased mitotic DNA replication at rDNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of DNA replication is decreased in ribosomal DNA repeats. FYPO_relaxed.owl FYPO:0007680 biolink:NamedThing increased ribonucleotide incorporation into DNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which more ribonucleotides than normal are incorporated into one or both strands during mitotic DNA replication. FYPO_relaxed.owl FYPO:0001753 biolink:NamedThing normal anaerobic cell population growth A cell population phenotype in which a population of cells grow normally (i.e. indistinguishably from wild type) under anaerobic conditions. FYPO_relaxed.owl FYPO:0001814 biolink:NamedThing normal cell population growth during iron starvation A cell growth phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) under iron starvation conditions. FYPO_relaxed.owl FYPO:0004183 biolink:NamedThing normal growth on papuamide B during mating A phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing papuamide B when cells in the population are undergoing conjugation. FYPO_relaxed.owl FYPO:0004765 biolink:NamedThing normal cell population growth during glucose starvation A cell growth phenotype in which cell population growth is normal (i.e. indistinguishable from wild type) under conditions of glucose starvation. FYPO_relaxed.owl FYPO:0001650 biolink:NamedThing decreased lysine import A cellular process phenotype in which the import of lysine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001365 biolink:NamedThing decreased rate of actomyosin contractile ring contraction A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actomyosin contractile ring contraction is decreased. Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts. FYPO_relaxed.owl FYPO:0004430 biolink:NamedThing premature actomyosin contractile ring contraction A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction begins earlier than normal, e.g. before the mitotic spindle has completely disassembled. Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts. FYPO_relaxed.owl FYPO:0004653 biolink:NamedThing delayed onset of actomyosin contractile ring contraction A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction begins later than normal. FYPO_relaxed.owl FYPO:0005543 biolink:NamedThing increased duration of actomyosin contractile ring contraction A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of actomyosin contractile ring contraction is longer than normal. FYPO_relaxed.owl FYPO:0005903 biolink:NamedThing incomplete actomyosin contractile ring contraction A cell phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction begins, but stops before the ring completely constricts and is disassembled. FYPO_relaxed.owl FYPO:0006897 biolink:NamedThing increased rate of actomyosin contractile ring contraction A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actomyosin contractile ring contraction is increased. Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts. FYPO_relaxed.owl FYPO:0006939 biolink:NamedThing asymmetric actomyosin contractile ring contraction A cell phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction progresses in a radially asymmetric fashion. FYPO_relaxed.owl FYPO:0001368 biolink:NamedThing normal actomyosin contractile ring assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring assembly is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002443 biolink:NamedThing normal rate of actin cable retrograde transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin cable retrograde transport is normal (i.e. indistinguishable from wild type). The process results in arrangement of actin cables from the periphery toward the interior of the cell. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts. FYPO_relaxed.owl FYPO:0005899 biolink:NamedThing normal rate of actin filament-based movement A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin filament-based movement is normal (i.e. indistinguishable from wild type). Actin filament-based movement is the movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. FYPO_relaxed.owl FYPO:0005904 biolink:NamedThing normal rate of protein exchange in actomyosin contractile ring A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of protein exchange in the actomyosin contractile ring is normal (i.e. indistinguishable from wild type). Normally, proteins including actin and myosin are turned over between the contractile ring and elsewhere in the cytoplasm; exchange is faster during than before ring constriction. FYPO_relaxed.owl FYPO:0005906 biolink:NamedThing normal onset of actomyosin contractile ring contraction A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cgontractile ring contraction begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events. FYPO_relaxed.owl FYPO:0006082 biolink:NamedThing normal actin filament depolymerization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin filament depolymerization, i.e. the removal of actin monomers from an actin filament, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006178 biolink:NamedThing normal rate of actin cortical patch localization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin cortical patch localization is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007061 biolink:NamedThing normal Arp2/3 complex-mediated actin nucleation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin monomers associate to form a new branch on the side of an existing actin filament, mediated by the Arp2/3 protein complex, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007902 biolink:NamedThing normal onset of cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic cytokinesis begins at the same time as normal. FYPO_relaxed.owl FYPO:0007828 biolink:NamedThing normal actomyosin contractile ring maturation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin contractile ring maturation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001374 biolink:NamedThing abolished protein localization to medial cortex in spores A cell phenotype in which the localization of a protein to the medial cortex of a spore is abolished. FYPO_relaxed.owl FYPO:0002555 biolink:NamedThing abolished protein localization to medial cortex during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is abolished. FYPO_relaxed.owl FYPO:0001376 biolink:NamedThing normal cellular calcium level during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell during a cellular response to salt stress is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001461 biolink:NamedThing normal immediate intracellular calcium spike following extracellular calcium stimulus A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases normally immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a "burst" within one minute, and then decreases to a new steady-state concentration. FYPO_relaxed.owl FYPO:0001377 biolink:NamedThing decreased cellular calcium level during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell during a cellular response to salt stress is lower than normal. FYPO_relaxed.owl FYPO:0001950 biolink:NamedThing decreased sequestered calcium level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion determined to be sequestered in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001378 biolink:NamedThing increased cellular calcium level during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in a cell during a cellular response to salt stress is higher than normal. FYPO_relaxed.owl FYPO:0003562 biolink:NamedThing normal horsetail nucleus morphology A physical cellular phenotype in which the size, shape, or structure of the horsetail nucleus is normal (i.e. indistinguishable from wild type). The horsetail nucleus forms during the rapid oscillatory movement at meiotic prophase I. FYPO_relaxed.owl FYPO:0006668 biolink:NamedThing normal nuclear morphology during G0 A physical cellular phenotype observed during G0 phase in which the size, shape, or structure of the nucleus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001385 biolink:NamedThing inviable after spore germination, without cell division, cell cycle arrest with replicated DNA A phenotype in which a spore germinates to produce a cell that enters the cell cycle but then undergoes cell cycle arrest with replicated DNA, and eventually dies. FYPO_relaxed.owl FYPO:0005710 biolink:NamedThing abnormal negative regulation of DNA replication initiation resulting in complete rereplication, with mitotic cell cycle arrest A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of DNA-dependent DNA replication is abnormal, resulting in one or more rounds of rereplication of the entire genome, followed by cell cycle arrest. FYPO_relaxed.owl FYPO:0002263 biolink:NamedThing inviable after spore germination, without cell division, cell cycle arrest, elongated cell A phenotype in which a spore germinates to produce a cell that enters the cell cycle but then becomes elongated and undergoes cell cycle arrest, and eventually dies without completing cell division. FYPO_relaxed.owl FYPO:0004473 biolink:NamedThing inviable after spore germination, without cell division, cell cycle arrest with unreplicated DNA A phenotype in which a spore germinates to produce a cell that enters the cell cycle but then undergoes cell cycle arrest with unreplicated DNA, and eventually dies. FYPO_relaxed.owl FYPO:0001389 biolink:NamedThing normal nucleus positioning A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleus localization is normal. FYPO_relaxed.owl FYPO:0007912 biolink:NamedThing normal mitochondrial distribution A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial localization is normal. FYPO_relaxed.owl FYPO:0001391 biolink:NamedThing mislocalized septum, near new end A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum closer to the new end of the cell (when the new end is not yet growing), instead of at the midpoint of the long axis. FYPO_relaxed.owl FYPO:0003210 biolink:NamedThing mislocalized, misoriented septum A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a septum that is in an abnormal location and is not perpendicular to the long axis of the cell. The normal location is at the midpoint of the long axis of the cell. FYPO_relaxed.owl FYPO:0005872 biolink:NamedThing incomplete septum formed from asymmetrically located sites A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the septum is in two asymmetrically located parts and does not completely bisect the cell. Arises when septum assembly begins at two sites which are not on opposite sides of the medial cortex and terminates prematurely on both sides. FYPO_relaxed.owl FYPO:0001394 biolink:NamedThing activation of monopolar cell growth at either end A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth may occur at either the new or old end of the cell, instead of exclusively at the old end, following cell division. A population of cells with this phenotype has a 1:1 mix of cells initiating growth at the new end and cells initiating growth at the old end. FYPO_relaxed.owl FYPO:0003314 biolink:NamedThing activation of monopolar cell growth at new end A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth occurs at the new end of the cell, instead of at the old end, following cell division. FYPO_relaxed.owl FYPO:0004109 biolink:NamedThing delayed activation of monopolar cell growth A regulation phenotype observed in the vegetative growth phase of the life cycle in which the activation of monopolar cell growth, i.e. the initiation of growth at the old end of a cell following cell division, begins later than normal. FYPO_relaxed.owl FYPO:0001397 biolink:NamedThing monopolar actin cortical patch localization to old end A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized to only the old end of a cell following cell division. FYPO_relaxed.owl FYPO:0001398 biolink:NamedThing monopolar actin cortical patch localization to either end A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized to only one end of a cell following cell division; patches may localize to either the old or the new end. A population of cells with this phenotype has a 1:1 mix of cells with actin patches at the old end and cells with patches at the new end. FYPO_relaxed.owl FYPO:0007997 biolink:NamedThing monopolar actin cortical patch localization to new end A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized to only the new end of a cell following cell division. FYPO_relaxed.owl FYPO:0001400 biolink:NamedThing normal interphase microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, and morphology of cytoplasmic microtubules is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005688 biolink:NamedThing normal astral microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, and morphology of astral microtubules is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002674 biolink:NamedThing normal protein localization to plasma membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001404 biolink:NamedThing irregular colony morphology A colony morphology phenotype in which the outline of a colony growing on a solid surface is not symmetrical. FYPO_relaxed.owl FYPO:0001405 biolink:NamedThing glossy colony morphology A colony morphology phenotype in which a colony growing on a solid surface has an abnormally glossy surface. FYPO_relaxed.owl FYPO:0002296 biolink:NamedThing cone-shaped colony morphology A colony morphology phenotype in which the colony spreads laterally to a lesser extent, and grows vertically to a greater extent, resulting in a more conical shape, than a wild-type colony. FYPO_relaxed.owl FYPO:0001406 biolink:NamedThing increased septum thickness A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that is thicker than normal. FYPO_relaxed.owl FYPO:0002025 biolink:NamedThing inviable elongated multinucleate vegetative cell with abnormal septum morphology A cell morphology phenotype in which a vegetative cell is inviable, is elongated, contains a septum with abnormal morphology (i.e. size, shape, or structure), and contain more than one nucleus. FYPO_relaxed.owl FYPO:0003203 biolink:NamedThing curved septum A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that is curved. FYPO_relaxed.owl FYPO:0003212 biolink:NamedThing kinked septum A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that is kinked, i.e. has multiple angles along its length. FYPO_relaxed.owl FYPO:0003439 biolink:NamedThing branched septum A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that has branches. For example, the septum may be Y-shaped. FYPO_relaxed.owl FYPO:0005870 biolink:NamedThing incomplete septum A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that does not completely bisect the cell. FYPO_relaxed.owl FYPO:0006900 biolink:NamedThing decreased septum thickness A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that is thinner than normal. FYPO_relaxed.owl FYPO:0001408 biolink:NamedThing sensitive to heat shock A cell phenotype in which cells show increased sensitivity to heat shock. Heat shock is a form of heat stress in which cells are briefly exposed to a very high temperature. FYPO_relaxed.owl FYPO:0003065 biolink:NamedThing abnormal microtubule cytoskeleton morphology during mating A physical cellular phenotype in which the size, shape, or structure of the microtubule cytoskeleton is abnormal during conjugation with cellular fusion. FYPO_relaxed.owl FYPO:0004246 biolink:NamedThing abnormal microtubule cytoskeleton morphology during meiotic prophase I A physical cellular phenotype in which the size, shape, or structure of the microtubule cytoskeleton is abnormal during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0002004 biolink:NamedThing microtubules absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable microtubules of one or more types. FYPO_relaxed.owl FYPO:0002400 biolink:NamedThing single microtubule bundle during mitotic interphase A physical cellular phenotype observed during mitotic interphase in which all detectable microtubules are present in a single bundle. FYPO_relaxed.owl FYPO:0003227 biolink:NamedThing interphase microtubules present during mitosis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the long cytoplasmic microtubules characteristic of interphase cells remain present after mitosis begins and the mitotic spindle forms. FYPO_relaxed.owl FYPO:0004088 biolink:NamedThing abnormal cytoplasmic microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the morphology of cytoplasmic microtubules is abnormal. FYPO_relaxed.owl FYPO:0004316 biolink:NamedThing abnormal post-anaphase array A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount, distribution, or morphology of all or part of the post-anaphase array of microtubules is abnormal. FYPO_relaxed.owl FYPO:0004732 biolink:NamedThing astral microtubules present in decreased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer astral microtubules than normal. FYPO_relaxed.owl FYPO:0005687 biolink:NamedThing eMTOC absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain a detectable equatorial microtubule organizing center (eMTOC). FYPO_relaxed.owl FYPO:0006376 biolink:NamedThing decreased protein processing during nitrogen starvation A cellular metabolism phenotype in which the observed occurrence of protein processing is decreased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0005443 biolink:NamedThing decreased proteolysis during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of hydrolysis of peptide bonds within a protein is decreased. All proteolysis may be affected, or only cleavage of specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0001423 biolink:NamedThing normal protein targeting to vacuole A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein targeting to the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004248 biolink:NamedThing normal protein localization to vacuolar membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuolar membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002962 biolink:NamedThing abolished protein localization to Mei2 nuclear dot A cell phenotype in which the localization of a protein to the Mei2 nuclear dot is abolished. FYPO_relaxed.owl FYPO:0003451 biolink:NamedThing abolished protein localization to nucleus during meiotic anaphase II A cell phenotype in which the localization of a protein to the nucleus is abolished during anaphase of the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0004462 biolink:NamedThing abolished protein localization to nucleus during nitrogen starvation A cell phenotype in which the localization of a protein to the nucleus is abolished when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0004463 biolink:NamedThing abolished protein localization to nucleus during glucose starvation A cell phenotype in which the localization of a protein to the nucleus is abolished when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0006674 biolink:NamedThing abolished protein localization to nucleus during mating A cell phenotype in which the localization of a protein to the nucleus is abolished during conjugation. FYPO_relaxed.owl FYPO:0006685 biolink:NamedThing abolished protein localization to mating partner nucleus in zygote A cellular process phenotype observed during mating in which the localization of a protein produced by one cell to the nucleus of its mating partner (i.e. of the opposite mating type) does not occur. Such protein localization normally occurs after cell fusion but prior to karyogamy. FYPO_relaxed.owl FYPO:0001425 biolink:NamedThing abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is abnormal, resulting in one or more rounds of rereplication of the entire genome. FYPO_relaxed.owl FYPO:0001426 biolink:NamedThing abnormal negative regulation of mitotic DNA replication initiation resulting in partial rereplication A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is abnormal, resulting in rereplication of part of the genome. FYPO_relaxed.owl FYPO:0001427 biolink:NamedThing abnormal negative regulation of mitotic DNA replication initiation resulting in slow rereplication A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is abnormal, resulting in a single round of rereplication of the entire genome, which takes place more slowly than normal replication. FYPO_relaxed.owl FYPO:0006241 biolink:NamedThing abnormal negative regulation of mitotic DNA replication initiation during cellular response to DNA damage A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is abnormal during a cellular response to DNA damage. May result in re-replication of all or part of the genome. FYPO_relaxed.owl FYPO:0007669 biolink:NamedThing viable swollen vegetative cell with complete DNA rereplication A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, has a larger volume than normal, and undergoes one or more rounds of rereplication of the entire genome. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0001428 biolink:NamedThing normal negative regulation of mitotic DNA replication initiation A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of mitotic DNA replication is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001441 biolink:NamedThing decreased SAGA complex localization to promoter region A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of the SAGA complex to chromatin at promoters is decreased. FYPO_relaxed.owl FYPO:0004589 biolink:NamedThing abnormal gamma-tubulin complex localization to mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which localization of the gamma-tubulin complex to the spindle pole body is abnormal. FYPO_relaxed.owl FYPO:0001442 biolink:NamedThing decreased histone H3-K9 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004239 biolink:NamedThing decreased histone H3-K4 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 4 of histone H3 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004240 biolink:NamedThing decreased histone H3-K56 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 56 of histone H3 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007218 biolink:NamedThing decreased histone H3-K18 acetylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 18 of histone H3 in regions containing protein-coding genes occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001443 biolink:NamedThing abolished transcription during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription does not occur. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0001852 biolink:NamedThing decreased transcription during iron starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal when the cell is subject to iron ion starvation. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002783 biolink:NamedThing decreased transcription during cellular response to nitric oxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal during a cellular response to nitric oxide. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002784 biolink:NamedThing decreased transcription during cellular response to salt stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal during a cellular response to a salt stress. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002894 biolink:NamedThing decreased transcription during cellular response to calcium ion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal during a cellular response to calcium ions. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0004009 biolink:NamedThing decreased rRNA transcription A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription of ribosomal DNA into ribosomal RNA occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005229 biolink:NamedThing decreased transcription from RNA polymerase II promoter during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from one or more RNA polymerase II promoters occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006544 biolink:NamedThing decreased transcription during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal during mitosis. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0006676 biolink:NamedThing decreased transcription during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a lower extent than normal during a cellular response to hydroxyurea. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0007613 biolink:NamedThing decreased transcription from STREP promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more STREP motifs occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0002879 biolink:NamedThing abolished transcription during glucose starvation A cellular process phenotype in which transcription does not occur when the cell is subject to glucose starvation. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0004986 biolink:NamedThing abolished transcription during meiotic cell cycle A cellular process phenotype in which transcription does not occur during the meiotic cell cycle. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0006148 biolink:NamedThing abolished transcription during nitrogen starvation A cellular process phenotype in which transcription does not occur when the cell is subject to nitrogen starvation. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002686 biolink:NamedThing increased cellular trehalose level in spore A cell phenotype in which the amount of trehalose measured in a spore is higher than normal. FYPO_relaxed.owl FYPO:0001445 biolink:NamedThing increased cellular trehalose level during heat shock A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is higher than normal when the cell is subject to heat shock. FYPO_relaxed.owl FYPO:0001502 biolink:NamedThing increased cellular trehalose level during cellular response to osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is higher than normal during a cellular response to osmotic stress. FYPO_relaxed.owl FYPO:0001451 biolink:NamedThing resistance to freezing A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show decreased sensitivity to freezing. FYPO_relaxed.owl FYPO:0001465 biolink:NamedThing decreased immediate intracellular calcium spike following extracellular calcium stimulus A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration briefly increases to a lesser extent than normal immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a "burst" within one minute, and then decreases to a new steady-state concentration. FYPO_relaxed.owl FYPO:0001466 biolink:NamedThing abolished immediate intracellular calcium spike following extracellular calcium stimulus A cell phenotype observed in the vegetative growth phase of the life cycle in which the intracellular calcium ion (Ca2+) concentration does not increase immediately following an extracellular Ca2+ stimulus. Normally, the intracellular Ca2+ concentration increases to a peak in a "burst" within one minute, and then decreases to a new steady-state concentration. FYPO_relaxed.owl FYPO:0001469 biolink:NamedThing increased steady-state intracellular calcium level following extracellular calcium stimulus A cell phenotype observed in the vegetative growth phase of the life cycle in which the steady-state intracellular calcium ion (Ca2+) concentration increases to a greater extent than normal following an extracellular Ca2+ stimulus. Normally, a dose-dependent increased steady-state Ca2+ concentration is reached within 2-3 minutes of extracellular Ca2+ addition, and is sustained for several hours. FYPO_relaxed.owl FYPO:0001471 biolink:NamedThing normal growth on tacrolimus during salt stress A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing tacrolimus, when the cell is subject to salt stress. FYPO_relaxed.owl FYPO:0001473 biolink:NamedThing resistance to tacrolimus during salt stress An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of tacrolimus than normal when the cells are subject to salt stress. FYPO_relaxed.owl FYPO:0006404 biolink:NamedThing fragmented spindle pole body A cell phenotype in which the spindle pole body is broken into fragments. FYPO_relaxed.owl FYPO:0006406 biolink:NamedThing abnormal spindle pole body morphology during meiotic cell cycle A physical cellular phenotype in which the size, shape, or structure of the spindle pole body is abnormal during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0001475 biolink:NamedThing fragmented mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle pole body is broken into fragments. FYPO_relaxed.owl FYPO:0004613 biolink:NamedThing abolished microtubule attachment to spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which the spindle pole body is not attached to any interphase cytoplasmic microtubules; as a result, the microtubules are not connected to the nucleus. Normally, the spindle pole body is attached to at least one cytoplasmic microtubule bundle. FYPO_relaxed.owl FYPO:0006431 biolink:NamedThing enlarged mitotic spindle pole body A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle pole body is larger than normal. FYPO_relaxed.owl FYPO:0006405 biolink:NamedThing fragmented meiotic spindle pole body A cell phenotype in which the meiotic spindle pole body is broken into fragments. FYPO_relaxed.owl FYPO:0001482 biolink:NamedThing alpha,alpha-trehalase activity increase abolished during cellular response to heat A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity does not increase as a result of a heat stimulus. FYPO_relaxed.owl FYPO:0003458 biolink:NamedThing alpha,alpha-trehalase activity increase abolished during cellular response to salt stress A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity does not increase as a result of a salt stress stimulus. FYPO_relaxed.owl FYPO:0005663 biolink:NamedThing abnormal re-entry into mitotic cell cycle after arrest in response to heat shock A cellular process phenotype in which re-entry into the mitotic cell cycle is abnormal after arrest resulting from heat shock. FYPO_relaxed.owl FYPO:0001483 biolink:NamedThing normal alpha,alpha-trehalase activity increase during cellular response to oxidative stress A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity increases normally (i.e. as in wild type) as a result of oxidative stress. FYPO_relaxed.owl FYPO:0001682 biolink:NamedThing normal alpha,alpha-trehalase activity increase during cellular response to salt stress A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity increases normally (i.e. as in wild type) as a result of a salt stress. FYPO_relaxed.owl FYPO:0003265 biolink:NamedThing normal alpha,alpha-trehalase activity increase during cellular response to heat stress A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity increases normally (i.e. as in wild type) as a result of a heat stress. FYPO_relaxed.owl FYPO:0003266 biolink:NamedThing normal alpha,alpha-trehalase activity during cellular response to nutrient A molecular function phenotype in which the observed rate of alpha,alpha-trehalase activity is normal (i.e. indistinguishable from wild type) during a cellular response to nutrient. FYPO_relaxed.owl FYPO:0001486 biolink:NamedThing normal RNA level during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to salt stress is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002113 biolink:NamedThing inviable curved vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0006197 biolink:NamedThing inviable mononucleate vegetative cell, with normal cell length and increased cell diameter A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, has one nucleus, and has normal length but a greater diameter than normal. FYPO_relaxed.owl FYPO:0006794 biolink:NamedThing inviable branched, swollen vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, branched, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0002107 biolink:NamedThing inviable stubby vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable, and the cell diameter is larger than normal and the cell length is shorter than normal. FYPO_relaxed.owl FYPO:0002111 biolink:NamedThing inviable tapered vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell. FYPO_relaxed.owl FYPO:0002415 biolink:NamedThing inviable swollen vegetative cell with abnormal cell shape A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, and has an abnormal shape and a larger volume than normal. FYPO_relaxed.owl FYPO:0002904 biolink:NamedThing inviable pear-shaped vegetative cell A cell morphology phenotype in which a cell is inviable and shaped in the form of a pear in the vegetative growth phase of the life cycle. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell. FYPO_relaxed.owl FYPO:0003333 biolink:NamedThing inviable lemon-shaped cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell is inviable, and grows in the form of a lemon prior to cell death. A lemon shape is defined mathematically as having a quadric surface in three dimensions obtained by rotating less than half of a circular arc about an axis passing through the endpoints of the arc. FYPO_relaxed.owl FYPO:0001877 biolink:NamedThing viable thin vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable but has an abnormally low thickness or diameter. FYPO_relaxed.owl FYPO:0002106 biolink:NamedThing viable stubby vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable, but the cell diameter is larger than normal and the cell length is shorter than normal. FYPO_relaxed.owl FYPO:0002110 biolink:NamedThing viable tapered vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable, and tapers at one end to a diameter smaller than the other. The cell diameter at the narrow end is smaller than that of a wild-type cell. FYPO_relaxed.owl FYPO:0002112 biolink:NamedThing viable curved vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0002402 biolink:NamedThing viable swollen vegetative cell with abnormal cell shape A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, and has an abnormal shape and a larger volume than normal. FYPO_relaxed.owl FYPO:0002903 biolink:NamedThing viable pear-shaped vegetative cell A cell morphology phenotype in which a cell is viable and shaped in the form of a pear in the vegetative growth phase of the life cycle. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell. FYPO_relaxed.owl FYPO:0004256 biolink:NamedThing viable lemon-shaped cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell is viable, and grows in the form of a lemon. A lemon shape is defined mathematically as having a quadric surface in three dimensions obtained by rotating less than half of a circular arc about an axis passing through the endpoints of the arc. FYPO_relaxed.owl FYPO:0004517 biolink:NamedThing viable vegetative cell enlarged around nucleus A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable and has a diameter larger than normal only near the middle of the cell, around the nucleus. FYPO_relaxed.owl FYPO:0007231 biolink:NamedThing viable spindle-shaped cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a single cell is viable, and grows in the form of a spindle. FYPO_relaxed.owl FYPO:0002191 biolink:NamedThing inviable swollen septated spheroid vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is shaped in the form of a spheroid, has one or more septa, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0002282 biolink:NamedThing inviable curved septated vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is curved along the long axis, and has one or more septa. FYPO_relaxed.owl FYPO:0001878 biolink:NamedThing viable thin, elongated vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable but is elongated and has an abnormally low thickness or diameter. FYPO_relaxed.owl FYPO:0002215 biolink:NamedThing viable curved elongated vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable, is elongated, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0002480 biolink:NamedThing viable after spore germination with elongated germ tube A phenotype in which a spore germinates to produce an elongated germ tube, and subsequently forms a viable dividing cell. FYPO_relaxed.owl FYPO:0003481 biolink:NamedThing viable elongated vegetative cell, elongated upon mitotic entry A cell morphology phenotype in which a vegetative cell is viable and elongated, and in which mitosis begins when the cell is longer than normal. FYPO_relaxed.owl FYPO:0004970 biolink:NamedThing viable elongated vegetative cell during phosphate starvation A cell morphology phenotype in which a vegetative cell is viable and elongated when the cell is subject to phosphate starvation. FYPO_relaxed.owl FYPO:0006617 biolink:NamedThing viable elongated vegetative cell with increased cell diameter A cell morphology phenotype in which a vegetative cell is viable, elongated, and has a greater diameter than normal. FYPO_relaxed.owl FYPO:0007086 biolink:NamedThing elongated vegetative cell during sulfur starvation A cell morphology phenotype in which a vegetative cell is elongated when the cell is subject to sulfur starvation. FYPO_relaxed.owl FYPO:0001504 biolink:NamedThing decreased cellular trehalose level during sporulation A cell phenotype in which the amount of trehalose measured in a cell is lower than normal during sporulation. FYPO_relaxed.owl FYPO:0002662 biolink:NamedThing decreased cellular trehalose level during heat shock A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is lower than normal when the cell is subject to heat shock. FYPO_relaxed.owl FYPO:0001507 biolink:NamedThing normal cellular phosphatidylinositol level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002228 biolink:NamedThing normal cellular phosphatidylethanolamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylethanolamine measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002315 biolink:NamedThing normal cellular FPP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of all-trans-farnesyl diphosphate (FPP) measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005589 biolink:NamedThing normal cellular phosphatidylserine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylserine measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005590 biolink:NamedThing normal cellular cardiolipin level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of cardiolipin measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005753 biolink:NamedThing normal cellular dNTP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more 2'-deoxyribonucleoside triphosphates (dNTPs) measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005756 biolink:NamedThing normal cellular mannosylinositol phosphorylceramide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mannosylinositol phosphorylceramide (MIPC) measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006204 biolink:NamedThing normal cellular dCTP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dCTP measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001680 biolink:NamedThing abolished protein localization to chromatin during premeiotic DNA replication A cell phenotype in which the localization of a protein to chromatin is abolished during the round of DNA replication that precedes meiosis I. FYPO_relaxed.owl FYPO:0001681 biolink:NamedThing abolished protein localization to chromatin during S phase of meiotic cell cycle A cell phenotype in which the localization of a protein to chromatin is abolished during S phase of a meiotic cell cycle. FYPO_relaxed.owl FYPO:0006161 biolink:NamedThing abolished protein localization to chromatin during meiosis I A cell phenotype in which the localization of a protein to chromatin is abolished during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007649 biolink:NamedThing abolished protein localization to pericentric heterochromatin during meiosis II A cell phenotype in which the localization of a protein to pericentric heterochromatin is abolished during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0007650 biolink:NamedThing abolished protein localization to pericentric heterochromatin during meiotic prophase I A cell phenotype in which the localization of a protein to pericentric heterochromatin is abolished during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006163 biolink:NamedThing normal protein localization to chromatin A cell phenotype in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006162 biolink:NamedThing normal protein localization to chromatin during meiosis I A cell phenotype in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0004521 biolink:NamedThing inviable after spore germination, single or double cell division, branched, elongated cell A phenotype in which a spore germinates to produce a cell that is elongated and branched (and septated), and undergoes one or two rounds of cell division and then dies. FYPO_relaxed.owl FYPO:0007282 biolink:NamedThing viable branched, swollen vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable and branched, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0004457 biolink:NamedThing decreased protein localization to nucleus during nitrogen starvation A cell phenotype in which the localization of a protein to the nucleus is decreased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006185 biolink:NamedThing decreased protein localization to nucleus during prophase I A cell phenotype in which the localization of a protein to the nucleus is decreased during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0008107 biolink:NamedThing decreased protein localization to nucleus during stationary phase A cell phenotype in which the localization of a protein to the nucleus is decreased during stationary phase. FYPO_relaxed.owl FYPO:0007769 biolink:NamedThing increased heterochromatin tethering at nuclear periphery during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin tethering at the nuclear periphery persists after the onset of mitosis. Normally, heterochromatic parts of chromosomes, such as centromeres and telomeres, are maintained at the nuclear periphery during interphase and released during mitosis. FYPO_relaxed.owl FYPO:0001529 biolink:NamedThing decreased GTP binding A molecular function phenotype in which occurrence of GTP binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001724 biolink:NamedThing increased GTP binding A molecular function phenotype in which occurrence of GTP binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001555 biolink:NamedThing formation of abnormal tRNA processing intermediates A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the intermediate RNAs formed during tRNA processing differ from wild type in size. FYPO_relaxed.owl FYPO:0001560 biolink:NamedThing decreased cellular threonine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-threonine measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001561 biolink:NamedThing decreased cellular citrulline level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-citrulline measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001562 biolink:NamedThing decreased cellular histidine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidine measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001564 biolink:NamedThing decreased cellular ornithine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-ornithine measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001616 biolink:NamedThing decreased cellular valine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-valine measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0001617 biolink:NamedThing decreased cellular isoleucine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-isoleucine measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0001619 biolink:NamedThing decreased cellular lysine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-lysine measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0001621 biolink:NamedThing decreased cellular arginine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-arginine measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0001727 biolink:NamedThing decreased cellular glutamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0002748 biolink:NamedThing decreased cellular alanine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-alanine measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0002749 biolink:NamedThing decreased cellular asparagine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-asparagine measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0005240 biolink:NamedThing decreased cellular tryptophan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tryptophan measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0005241 biolink:NamedThing decreased cellular tyrosine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tyrosine measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0005257 biolink:NamedThing decreased cellular proline level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-proline measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006696 biolink:NamedThing decreased cellular S-adenosyl-L-homocysteine level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of S-adenosyl-L-homocysteine (SAH) measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0001565 biolink:NamedThing increased cellular threonine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-threonine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001566 biolink:NamedThing increased cellular citrulline level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-citrulline measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001567 biolink:NamedThing increased cellular histidine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001569 biolink:NamedThing increased cellular ornithine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-ornithine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001728 biolink:NamedThing increased cellular serine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-serine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003457 biolink:NamedThing increased cellular homocysteine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of homocysteine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003516 biolink:NamedThing increased cellular L-ergothioneine level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-ergothioneine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003518 biolink:NamedThing increased cellular hercynine level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of hercynine (N(alpha),N(alpha),N(alpha)-trimethyl-L-histidine) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0005237 biolink:NamedThing increased cellular proline level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-proline measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0005238 biolink:NamedThing increased cellular tryptophan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tryptophan measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0005239 biolink:NamedThing increased cellular tyrosine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tyrosine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0005263 biolink:NamedThing increased cellular arginine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-arginine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006697 biolink:NamedThing increased cellular methionine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-methionine measured in the cell is higher than normal. FYPO_relaxed.owl FYPO:0006951 biolink:NamedThing increased cellular N(alpha),N(alpha)-dimethyl-L-histidine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of N(alpha),N(alpha)-dimethyl-L-histidines measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006953 biolink:NamedThing increased cellular asparagine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-asparagine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006954 biolink:NamedThing increased cellular isoleucine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-isoleucine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006955 biolink:NamedThing increased cellular glutamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0001572 biolink:NamedThing abolished cell population growth on methionine nitrogen source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing L-methionine as the nitrogen source. FYPO_relaxed.owl FYPO:0001576 biolink:NamedThing abolished cell population growth on dipeptide nitrogen source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing a dipeptide such as Leu-Ala as the nitrogen source. FYPO_relaxed.owl FYPO:0001577 biolink:NamedThing abolished cell population growth on tetrapeptide nitrogen source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing a tetrapeptide such as Leu-Ser-Lys-Leu as the nitrogen source. FYPO_relaxed.owl FYPO:0001934 biolink:NamedThing abolished cell population growth on glycerol carbon source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing glycerol as the carbon source. FYPO_relaxed.owl FYPO:0002752 biolink:NamedThing abolished cell population growth on methionine sulfur source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing L-methionine as the sole sulfur source. FYPO_relaxed.owl FYPO:0002753 biolink:NamedThing abolished cell population growth on sulfate sulfur source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing sulfate ions as the sole sulfur source. FYPO_relaxed.owl FYPO:0003252 biolink:NamedThing abolished cell population growth on proline nitrogen source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing L-proline as the nitrogen source. FYPO_relaxed.owl FYPO:0003502 biolink:NamedThing abolished cell population growth on raffinose carbon source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing raffinose as the carbon source. FYPO_relaxed.owl FYPO:0003648 biolink:NamedThing abolished cell population growth on xanthine nitrogen source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing xanthine as the nitrogen source. FYPO_relaxed.owl FYPO:0003649 biolink:NamedThing abolished cell population growth on hypoxanthine nitrogen source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing hypoxanthine as the nitrogen source. FYPO_relaxed.owl FYPO:0003690 biolink:NamedThing abolished cell population growth on glycerol/ethanol carbon source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing glycerol and ethanol as the carbon sources. FYPO_relaxed.owl FYPO:0003730 biolink:NamedThing abolished cell population growth on galactose carbon source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing galactose as the carbon source. FYPO_relaxed.owl FYPO:0003806 biolink:NamedThing abolished cell population growth on non-fermentable carbon source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing one or more non-fermentable substance(s) as the only carbon source(s). FYPO_relaxed.owl FYPO:0004338 biolink:NamedThing abolished cell population growth on ethanol carbon source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing ethanol as the carbon source. FYPO_relaxed.owl FYPO:0004391 biolink:NamedThing abolished cell population growth on uracil nitrogen source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing uracil as the nitrogen source. FYPO_relaxed.owl FYPO:0004481 biolink:NamedThing abolished cell population growth at high temperature A vegetative cell population growth phenotype in which a cell population does not grow at high temperatures. FYPO_relaxed.owl FYPO:0004587 biolink:NamedThing abolished cell population growth on urea nitrogen source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing urea as the nitrogen source. FYPO_relaxed.owl FYPO:0004837 biolink:NamedThing abolished cell population growth during glucose starvation A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing little or no glucose. FYPO_relaxed.owl FYPO:0005369 biolink:NamedThing abolished cell population growth at low temperature A vegetative cell population growth phenotype in which a cell population does not grow at low temperatures. FYPO_relaxed.owl FYPO:0005883 biolink:NamedThing abolished anaerobic cell population growth A vegetative cell population growth phenotype in which a cell population does not grow under anaerobic conditions. FYPO_relaxed.owl FYPO:0006141 biolink:NamedThing abolished cell population growth on gluconate carbon source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing gluconate as the carbon source. FYPO_relaxed.owl FYPO:0007675 biolink:NamedThing abolished cell population growth on sucrose carbon source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing sucrose as the carbon source. FYPO_relaxed.owl FYPO:0008022 biolink:NamedThing abolished cell population growth on alanine nitrogen source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing alanine as the nitrogen source. FYPO_relaxed.owl FYPO:0008023 biolink:NamedThing abolished cell population growth on leucine nitrogen source A vegetative cell population growth phenotype in which a cell population does not grow in a medium containing leucine as the nitrogen source. FYPO_relaxed.owl FYPO:0004802 biolink:NamedThing abnormal protein localization to shmoo tip A cell phenotype in which the localization of a protein to the tip of a shmoo, or mating projection, is abnormal. FYPO_relaxed.owl FYPO:0006895 biolink:NamedThing decreased protein localization to cell tip during meiosis A cell phenotype in which the localization of a protein to the cell tip is decreased during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0006896 biolink:NamedThing decreased mitochondrion localization to cell tip during meiosis A cell phenotype in which the localization of mitochondria to the cell tip is decreased during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0007285 biolink:NamedThing abnormal dynamic protein localization to cell tip A cell phenotype in which a protein that is normally dynamically localized to one or both cell tips shows an abnormal temporal pattern of localization. For example, a protein may move from one cell tip to the other at an altered frequency or amplitude. FYPO_relaxed.owl FYPO:0007527 biolink:NamedThing increased protein localization to cell tip during nitrogen starvation A cell phenotype in which the localization of a protein to the cell tip is increased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0001586 biolink:NamedThing decreased protein localization to cell tip during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is decreased. FYPO_relaxed.owl FYPO:0002852 biolink:NamedThing increased protein localization to cell tip during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is increased. FYPO_relaxed.owl FYPO:0004468 biolink:NamedThing decreased protein localization to cell tip during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is decreased during a cellular response to salt stress. FYPO_relaxed.owl FYPO:0005464 biolink:NamedThing abnormal maintenance of protein location at cell tip during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to one or both cell tip(s), but then remains there for a longer or shorter time than normal. FYPO_relaxed.owl FYPO:0005468 biolink:NamedThing increased protein localization to cell tip during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is increased during mitosis. FYPO_relaxed.owl FYPO:0005503 biolink:NamedThing abnormally monopolar protein localization to cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is normally localized to both cell tips is instead found at only one tip. FYPO_relaxed.owl FYPO:0005831 biolink:NamedThing abnormal protein transport along microtubule to cell tip during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cell tip is abnormal. Transport of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007709 biolink:NamedThing decreased protein localization to cell cortex of non-growing cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of a non-growing cell tip is decreased. FYPO_relaxed.owl FYPO:0001588 biolink:NamedThing decreased lysine import during nitrogen starvation A cellular process phenotype in which the import of lysine into the cell occurs to a lower extent than normal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0001652 biolink:NamedThing abnormal lysine import during nitrogen starvation A cellular process phenotype in which the import of lysine into the cell is abnormal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0003170 biolink:NamedThing increased arginine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of arginine into the cell occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0001607 biolink:NamedThing decreased vacuolar aspartate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-aspartate measured in the vacuole is lower than normal. FYPO_relaxed.owl FYPO:0001608 biolink:NamedThing decreased vacuolar glutamate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate measured in the vacuole is lower than normal. FYPO_relaxed.owl FYPO:0001609 biolink:NamedThing decreased vacuolar ornithine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-ornithine measured in the vacuole is lower than normal. FYPO_relaxed.owl FYPO:0001610 biolink:NamedThing decreased vacuolar lysine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-lysine measured in the vacuole is lower than normal. FYPO_relaxed.owl FYPO:0001611 biolink:NamedThing decreased vacuolar histidine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidine measured in the vacuole is lower than normal. FYPO_relaxed.owl FYPO:0001612 biolink:NamedThing decreased vacuolar arginine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-arginine measured in the vacuole is lower than normal. FYPO_relaxed.owl FYPO:0001732 biolink:NamedThing decreased vacuolar glutamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the vacuole is lower than normal. FYPO_relaxed.owl FYPO:0004369 biolink:NamedThing decreased vacuolar phytochelatin level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phytochelatin measured in the vacuole is lower than normal. FYPO_relaxed.owl FYPO:0001622 biolink:NamedThing normal vacuolar threonine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-threonine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001623 biolink:NamedThing normal vacuolar serine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-serine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001624 biolink:NamedThing normal vacuolar asparagine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-asparagine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001625 biolink:NamedThing normal vacuolar glutamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001626 biolink:NamedThing normal vacuolar glycine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001627 biolink:NamedThing normal vacuolar alanine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-alanine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001628 biolink:NamedThing normal vacuolar valine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-valine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001629 biolink:NamedThing normal vacuolar methionine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-methionine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001630 biolink:NamedThing normal vacuolar isoleucine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-isoleucine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001631 biolink:NamedThing normal vacuolar leucine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-leucine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001632 biolink:NamedThing normal vacuolar tyrosine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-tyrosine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001633 biolink:NamedThing normal vacuolar phenylalanine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-phenylalanine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001634 biolink:NamedThing normal vacuolar tryptophan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of tryptophan measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001729 biolink:NamedThing normal vacuolar cysteine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-cysteine measured in the vacuole is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001639 biolink:NamedThing normal cellular methionine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-methionine measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001726 biolink:NamedThing normal cellular cysteine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-cysteine measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004001 biolink:NamedThing normal cellular glutathione level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione (GSH) measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001662 biolink:NamedThing decreased cellular cAMP level during glucose starvation A cell phenotype in which the amount of trehalose measured in a cell is lower than normal when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0001665 biolink:NamedThing decreased cellular cAMP level during cellular response to glucose stimulus A cell phenotype in which the amount of cyclic AMP measured in a cell is lower than normal during a cellular response to glucose stimulus. FYPO_relaxed.owl FYPO:0001663 biolink:NamedThing increased cellular cAMP level during glucose starvation A cell phenotype in which the amount of cyclic AMP measured in a cell is higher than normal when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0001664 biolink:NamedThing increased cellular cAMP level during cellular response to glucose stimulus A cell phenotype in which the amount of cyclic AMP measured in a cell is higher than normal during a cellular response to glucose stimulus. FYPO_relaxed.owl FYPO:0001667 biolink:NamedThing normal cAMP level during glucose starvation A cell phenotype in which the amount of cyclic AMP measured in a cell during glucose starvation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001959 biolink:NamedThing normal cAMP level during nitrogen starvation A cell phenotype in which the amount of cyclic AMP measured in a cell during nitrogen starvation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002800 biolink:NamedThing normal protein degradation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is normal (i.e. indistinguishable from wild type). Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0003299 biolink:NamedThing normal protein degradation via N-end rule pathway during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitin-dependent protein degradation via the N-end rule pathway is normal (i.e. indistinguishable from wild type). In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation. FYPO_relaxed.owl FYPO:0005181 biolink:NamedThing normal protein degradation during cellular response to UV A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is normal (i.e. indistinguishable from wild type) when the cell is exposed to ultraviolet light. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0007880 biolink:NamedThing normal protein degradation during cellular response to methyl methanesulfonate A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is normal (i.e. indistinguishable from wild type) during a cellular response to methyl methanesulfonate. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0001671 biolink:NamedThing decreased GDP binding A molecular function phenotype in which occurrence of GDP binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002725 biolink:NamedThing decreased L-aminoadipate-semialdehyde dehydrogenase activity A molecular function phenotype in which the observed rate of L-aminoadipate-semialdehyde dehydrogenase activity is decreased. FYPO_relaxed.owl FYPO:0001676 biolink:NamedThing protein mislocalized to nucleus during mitotic S phase A cell phenotype in which a protein that is not normally found in the nucleus is observed there during S phase of a mitotic cell cycle. FYPO_relaxed.owl FYPO:0002073 biolink:NamedThing protein mislocalized to nucleus during cellular response to copper ion A cell phenotype in which a protein that is not normally found in the nucleus is observed there during a cellular response to copper ions. FYPO_relaxed.owl FYPO:0002843 biolink:NamedThing protein mislocalized to nucleoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the nucleoplasm is observed there. FYPO_relaxed.owl FYPO:0003716 biolink:NamedThing abolished protein localization to lateral cortical node, with protein mislocalized to nucleus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to Skb1-containing lateral cortical nodes is abolished, and the protein is present in the nucleus instead. FYPO_relaxed.owl FYPO:0003729 biolink:NamedThing protein mislocalized to nuclear periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the nuclear periphery is observed there. FYPO_relaxed.owl FYPO:0004471 biolink:NamedThing protein mislocalized to nucleolus during mitotic telophase A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the nucleolus is observed there during telophase of mitosis. FYPO_relaxed.owl FYPO:0005000 biolink:NamedThing protein mislocalized to nucleus during mitotic interphase A cell phenotype in which a protein that is not normally found in the nucleus is observed there during interphase of a mitotic cell cycle. FYPO_relaxed.owl FYPO:0006100 biolink:NamedThing decreased protein localization to cytoplasm, with protein mislocalized to nucleus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is decreased, and some of the protein is present in the nucleus instead. FYPO_relaxed.owl FYPO:0006795 biolink:NamedThing abolished protein localization to actin cortical patch, with protein mislocalized to nucleus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches is abolished, and some of the protein is present in the nucleus instead. FYPO_relaxed.owl FYPO:0002874 biolink:NamedThing premature protein localization to medial cortex during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex begins earlier than normal. FYPO_relaxed.owl FYPO:0003289 biolink:NamedThing abnormal protein localization to medial cortical node A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is abnormal. FYPO_relaxed.owl FYPO:0006853 biolink:NamedThing increased protein localization to medial cortex during mitotic telophase A cell phenotype in which the localization of a protein to the medial cortex is increased during mitotic telophase. FYPO_relaxed.owl FYPO:0003337 biolink:NamedThing increased protein localization to septum A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell septum is increased. FYPO_relaxed.owl FYPO:0001733 biolink:NamedThing abnormal mitotic spindle pole body separation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle pole body separation is abnormal. Spindle pole body separation is the process in which duplicated spindle pole bodies detach and migrate apart within the nuclear membrane. FYPO_relaxed.owl FYPO:0003304 biolink:NamedThing abnormal mitotic spindle midzone assembly A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which formation of the mitotic spindle midzone, the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap, is abnormal. FYPO_relaxed.owl FYPO:0004648 biolink:NamedThing delayed onset of mitotic spindle assembly A cellular process phenotype in which assembly of the mitotic spindle begins later than normal. FYPO_relaxed.owl FYPO:0003762 biolink:NamedThing normal mitotic spindle assembly checkpoint A cell cycle checkpoint phenotype in which the mitotic cell cycle spindle assembly checkpoint is normal (i.e. indistinguishable from wild type). The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. FYPO_relaxed.owl FYPO:0004474 biolink:NamedThing normal mitotic cell cycle DNA replication checkpoint A cell cycle checkpoint phenotype in which the mitotic cell cycle DNA replication checkpoint is normal (i.e. indistinguishable from wild type). The mitotic DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete. FYPO_relaxed.owl FYPO:0006904 biolink:NamedThing normal mitotic cell size control checkpoint A cell cycle checkpoint phenotype in which a mitotic cell size control checkpoint is normal (i.e. indistinguishable from wild type). A mitotic cell size control checkpoint normally prevents cell cycle progression until the cell reaches a certain size. FYPO_relaxed.owl FYPO:0001706 biolink:NamedThing normal mitotic DNA damage checkpoint during cellular response to ionizing radiation A cell cycle checkpoint phenotype in which any DNA damage checkpoint is normal (i.e. indistinguishable from wild type) when the cell is exposed to ionizing radiation. A DNA damage checkpoint normally regulates progression through the cell cycle in response to DNA damage. FYPO_relaxed.owl FYPO:0002102 biolink:NamedThing normal mitotic DNA damage checkpoint during cellular response to UV A cell cycle checkpoint phenotype in which any mitotic DNA damage checkpoint is normal (i.e. indistinguishable from wild type) when the cell is exposed to ultraviolet light. A DNA damage checkpoint normally regulates progression through the cell cycle in response to DNA damage. FYPO_relaxed.owl FYPO:0003530 biolink:NamedThing normal S-phase DNA damage checkpoint A cell cycle checkpoint phenotype in which the S-phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is normal (i.e. indistinguishable from wild type). The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0006437 biolink:NamedThing normal mitotic DNA damage checkpoint during cellular response to methyl methanesulfonate A cell cycle checkpoint phenotype in which the mitotic DNA damage checkpoint is normal (i.e. indistinguishable from wild type) when the cell is exposed to methyl methanesulfonate. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. FYPO_relaxed.owl FYPO:0004552 biolink:NamedThing normal cell cycle regulation during cellular response to ionizing radiation during mitotic G2 phase A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ionizing radiation exposure during mitotic G2 phase is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to ionizing radiation. FYPO_relaxed.owl FYPO:0001710 biolink:NamedThing stabilized iron-sulfur cluster binding A molecular function phenotype in which occurrence of iron-sulfur cluster binding by a gene product (usually a protein) in a mutant is stabilized, i.e. interactions between the iron-sulfur cluster and the gene product last longer than in wild type under any given set of conditions. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001711 biolink:NamedThing destabilized iron-sulfur cluster binding A molecular function phenotype in which occurrence of iron-sulfur cluster binding by a gene product (usually a protein) in a mutant is stabilized, i.e. interactions between the iron-sulfur cluster and the gene product do not last as long as in wild type under any given set of conditions. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005486 biolink:NamedThing increased iron-sulfur cluster binding A molecular function phenotype in which occurrence of iron-sulfur cluster binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005487 biolink:NamedThing decreased iron-sulfur cluster binding A molecular function phenotype in which occurrence of iron-sulfur cluster binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001714 biolink:NamedThing decreased malate import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of malate into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001716 biolink:NamedThing decreased succinate import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of succinate into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001718 biolink:NamedThing decreased malonic acid import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of malonic acid into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001722 biolink:NamedThing decreased sodium export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of sodium ions out of a cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001825 biolink:NamedThing increased sodium export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of sodium ions out of a cell occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0001731 biolink:NamedThing increased vacuolar glutamate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamate measured in the vacuole is higher than normal. FYPO_relaxed.owl FYPO:0004767 biolink:NamedThing increased vacuolar alanine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-alanine measured in the vacuole is higher than normal. FYPO_relaxed.owl FYPO:0004768 biolink:NamedThing increased vacuolar arginine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-arginine measured in the vacuole is higher than normal. FYPO_relaxed.owl FYPO:0004769 biolink:NamedThing increased vacuolar asparagine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-asparagine measured in the vacuole is higher than normal. FYPO_relaxed.owl FYPO:0004770 biolink:NamedThing increased vacuolar glutamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-glutamine measured in the vacuole is higher than normal. FYPO_relaxed.owl FYPO:0004771 biolink:NamedThing increased vacuolar glycine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycine measured in the vacuole is higher than normal. FYPO_relaxed.owl FYPO:0004772 biolink:NamedThing increased vacuolar histidine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-histidine measured in the vacuole is higher than normal. FYPO_relaxed.owl FYPO:0004773 biolink:NamedThing increased vacuolar lysine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-lysine measured in the vacuole is higher than normal. FYPO_relaxed.owl FYPO:0004774 biolink:NamedThing increased vacuolar proline level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-proline measured in the vacuole is higher than normal. FYPO_relaxed.owl FYPO:0004775 biolink:NamedThing increased vacuolar serine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-serine measured in the vacuole is higher than normal. FYPO_relaxed.owl FYPO:0004776 biolink:NamedThing increased vacuolar threonine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of L-threonine measured in the vacuole is higher than normal. FYPO_relaxed.owl FYPO:0002636 biolink:NamedThing delayed onset of mitotic spindle elongation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle elongation begins later than normal. FYPO_relaxed.owl FYPO:0003268 biolink:NamedThing decreased rate of mitotic spindle elongation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is decreased. FYPO_relaxed.owl FYPO:0004830 biolink:NamedThing arrested mitotic spindle elongation during anaphase B A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle elongation ends earlier than normal during anaphase B. Elongation stops before the spindle reaches its normal maximum length. FYPO_relaxed.owl FYPO:0005417 biolink:NamedThing premature mitotic spindle elongation A cellular process phenotype in which mitotic spindle elongation begins earlier than normal. FYPO_relaxed.owl FYPO:0006048 biolink:NamedThing unstable mitotic spindle A cell phenotype in which a mitotic spindle assembles, but does not remain at a constant length or gradually elongate. FYPO_relaxed.owl FYPO:0007958 biolink:NamedThing increased rate of mitotic spindle elongation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is increased during miotic M phase. FYPO_relaxed.owl FYPO:0007961 biolink:NamedThing transient abrupt spindle length decrease at anaphase onset A cell phenotype in which the spindle length decreases abruptly at anaphase onset. FYPO_relaxed.owl FYPO:0003566 biolink:NamedThing delayed onset of mitotic spindle pole body separation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle pole body separation begins later than normal. FYPO_relaxed.owl FYPO:0001736 biolink:NamedThing decreased iron-sulfur cluster transfer A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001738 biolink:NamedThing decreased pantothenate import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of pantothenate into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001739 biolink:NamedThing increased pantothenate import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of pantothenate into the cell occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0001741 biolink:NamedThing increased chromosomal translocation A cell phenotype in which chromosomal translocations occur more frequently than in wild type cells. In a chromosomal translocation, chromosome parts are exchanged between non-homologous chromosomes. FYPO_relaxed.owl FYPO:0001742 biolink:NamedThing increased isochromosome formation A cell phenotype in which isochromosome formation occurs more frequently than in wild type cells. In isochromosome formation, one chromosome arm is lost and the other arm is duplicated in its place. FYPO_relaxed.owl FYPO:0006507 biolink:NamedThing increased subtelomeric DNA amplification during G0 A cell phenotype in which duplication of DNA sequences in the subtelomeric region occur more frequently than in wild type cells during G0 phase. FYPO_relaxed.owl FYPO:0007424 biolink:NamedThing increased chromosomal truncation A cell phenotype in which chromosomal truncations occur more frequently than in wild type cells. FYPO_relaxed.owl FYPO:0001743 biolink:NamedThing increased isochromosome formation with preferential breakage in the imr region A cell phenotype in which isochromosome formation occurs more frequently than in wild type cells, and in which the break point is located in the imr region in the majority of cases. In isochromosome formation, one chromosome arm is lost and the other arm is duplicated in its place. FYPO_relaxed.owl FYPO:0001745 biolink:NamedThing increased biotin import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of biotin into the cell occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0003388 biolink:NamedThing decreased biotin import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of biotin into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001748 biolink:NamedThing decreased nickel import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of nickel ions into a cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001749 biolink:NamedThing sensitive to tacrolimus during salt stress A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to tacrolimus when the cell is subject to salt stress. FYPO_relaxed.owl FYPO:0001754 biolink:NamedThing growth auxotrophic for lysine and methionine Auxotrophy in which a cell is unable to synthesize lysine or methionine, and therefore requires lysine and methionine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0001755 biolink:NamedThing growth auxotrophic for lysine and cysteine Auxotrophy in which a cell is unable to synthesize lysine or cysteine, and therefore requires lysine and cysteine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0003456 biolink:NamedThing growth auxotrophic for methionine and purine Auxotrophy in which a cell is unable to synthesize methionine or purines, and therefore requires methionine and at least one purine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0003428 biolink:NamedThing growth auxotrophic for arginine and cysteine Auxotrophy in which a cell is unable to synthesize arginine or cysteine, and therefore requires arginine and cysteine in the medium for vegetative cell growth. FYPO_relaxed.owl FYPO:0001758 biolink:NamedThing increased protein phosphatase activity A molecular function phenotype in which the observed rate of a protein phosphatase activity is increased. FYPO_relaxed.owl FYPO:0001962 biolink:NamedThing abolished protein phosphatase activity A molecular function phenotype in which a protein phosphatase activity is absent. FYPO_relaxed.owl FYPO:0004414 biolink:NamedThing increased phosphatase activity during cellular response to phosphate starvation A molecular function phenotype in which the observed rate of a phosphatase activity is increased during a cellular response to phosphate starvation. FYPO_relaxed.owl FYPO:0004834 biolink:NamedThing increased phosphatase activity during cellular response to adenine starvation A molecular function phenotype in which the observed rate of a phosphatase activity is increased during a cellular response to adenine starvation. FYPO_relaxed.owl FYPO:0005483 biolink:NamedThing increased inositol phosphate phosphatase activity A molecular function phenotype in which the observed rate of an inositol phosphate phosphatase activity is increased. FYPO_relaxed.owl FYPO:0007041 biolink:NamedThing increased alkaline phosphatase activity A molecular function phenotype in which the observed rate of alkaline phosphatase activity is increased. FYPO_relaxed.owl FYPO:0007144 biolink:NamedThing increased deoxyribonuclease (pyrimidine dimer) activity during cellular response to UV A molecular function phenotype in which the observed rate of deoxyribonuclease (pyrimidine dimer) activity is increased during a cellular response to ultraviolet light. FYPO_relaxed.owl FYPO:0001759 biolink:NamedThing normal protein phosphatase activity A molecular function phenotype in which the observed rate of a protein phosphatase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003267 biolink:NamedThing normal acid phosphatase activity A molecular function phenotype in which the observed rate of acid phosphatase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007047 biolink:NamedThing normal alkaline phosphatase activity A molecular function phenotype in which the observed rate of alkaline phosphatase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001762 biolink:NamedThing normal tRNA modification A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA modification, the covalent alteration of one or more nucleotides within a tRNA molecule, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002586 biolink:NamedThing normal mitochondrial tRNA 3'-end processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial tRNA 3'-end processing is normal (i.e. indistinguishable from wild type). In mitochondrial tRNA 3'-end processing, the 3' end of a mitochondrial pre-tRNA molecule is converted to that of a mature mitochondrial tRNA. FYPO_relaxed.owl FYPO:0003599 biolink:NamedThing normal snRNA 3'-end processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of an snRNA molecule is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001763 biolink:NamedThing normal tRNA methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA methylation, the posttranscriptional addition of methyl groups to specific residues in a tRNA molecule, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007017 biolink:NamedThing normal tRNA pseudouridylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA pseudouridylation, the intramolecular conversion of uridine to pseudouridine in a tRNA molecule, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001764 biolink:NamedThing normal tRNA-Asp C48, C49, C60, C61 and C62 methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of methyl groups to the C48, C49, C60, C61 and C62 residues in a tRNA-Asp molecule, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007018 biolink:NamedThing normal tRNA guanosine 2'-O-methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 2'-O-methylguanosine is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007019 biolink:NamedThing normal tRNA guanosine 7-methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 7-methylguanosine is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007020 biolink:NamedThing normal tRNA guanosine N2-methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form N2-methylguanosine is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001766 biolink:NamedThing abnormal tRNA methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA methylation, the posttranscriptional addition of methyl groups to specific residues in a tRNA molecule, is abnormal. FYPO_relaxed.owl FYPO:0007026 biolink:NamedThing decreased tRNA wybutosine biosynthesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional modification of a guanosine residue in a tRNA molecule to form wybutosine occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001767 biolink:NamedThing decreased tRNA-Asp C48, C49, C60, C61 and C62 methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of methyl groups to the C48, C49, C60, C61 and C62 residues in a tRNA-Asp molecule, occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001769 biolink:NamedThing increased tRNA-Asp C38 methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of methyl groups to the C38 residue in a tRNA-Asp molecule, occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007021 biolink:NamedThing abolished tRNA cytosine 2'-O-methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a cytosine residue in a tRNA molecule to form 2'-O-methylcytidine does not occur. FYPO_relaxed.owl FYPO:0007022 biolink:NamedThing abolished tRNA guanosine 2'-O-methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 2'-O-methylguanosine does not occur. FYPO_relaxed.owl FYPO:0007023 biolink:NamedThing increased tRNA guanosine 1-methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 1-methylguanosine occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007024 biolink:NamedThing decreased tRNA guanosine 7-methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form 7-methylguanosine occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007025 biolink:NamedThing decreased tRNA guanosine N2-methylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional methylation of a guanosine residue in a tRNA molecule to form N2-methylguanosine occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0008129 biolink:NamedThing increased tRNA guanosine N2,N2-dimethylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of two methyl groups to the N2 position of a guanine residue in a tRNA molecule is increased. Normally, two methyl groups are transferred to the G26 residue. FYPO_relaxed.owl FYPO:0002763 biolink:NamedThing abnormal tRNA (guanine(9)-N(1))-methyltransferase activity A molecular function phenotype in which the observed rate of tRNA (guanine(9)-N(1))-methyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0001775 biolink:NamedThing abolished protein localization to eisosome filament A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the eisosome filament is abolished. FYPO_relaxed.owl FYPO:0002561 biolink:NamedThing abolished protein localization to actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring does not occur. FYPO_relaxed.owl FYPO:0003713 biolink:NamedThing abolished protein localization to lateral cortical node A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to Skb1-containing lateral cortical nodes does not occur. FYPO_relaxed.owl FYPO:0006060 biolink:NamedThing abolished protein localization to septin ring A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the septin ring does not occur. FYPO_relaxed.owl FYPO:0006116 biolink:NamedThing abolished protein localization to actin cortical patch A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cortical patches does not occur. FYPO_relaxed.owl FYPO:0006502 biolink:NamedThing abolished protein localization to cell cortex of cell tip during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips does not occur. FYPO_relaxed.owl FYPO:0002966 biolink:NamedThing normal protein localization to mitotic spindle A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002967 biolink:NamedThing normal protein localization to mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005707 biolink:NamedThing normal protein localization to eMTOC A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the equatorial microtubule organizing center (eMTOC) is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005708 biolink:NamedThing normal protein localization to iMTOC A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the interphase microtubule organizing center (iMTOC) is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005842 biolink:NamedThing normal protein localization to interphase microtubule A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a cytoplasmic microtubule is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0001777 biolink:NamedThing short eisosome filament A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the eisosome filament is shorter than normal. FYPO_relaxed.owl FYPO:0007439 biolink:NamedThing abnormal eisosome morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of eisosome is abnormal. For example, an eisosome may protrude into the cell interior. The eisosome consists of a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. FYPO_relaxed.owl FYPO:0007264 biolink:NamedThing long eisosome filament A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the eisosome filament is longer than normal. FYPO_relaxed.owl FYPO:0001783 biolink:NamedThing elongated, constricted nucleus A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is longer than normal and is constricted in the middle, resembling a figure 8. FYPO_relaxed.owl FYPO:0004950 biolink:NamedThing elongated vegetative cell with elongated oscillating nucleus A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is elongated, and the nucleus is longer than normal and undergoes oscillatory movement. FYPO_relaxed.owl FYPO:0001784 biolink:NamedThing excess endoplasmic reticulum membrane present A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more endoplasmic reticulum (ER) membrane than normal. Excess ER membranes may form abnormal structures. FYPO_relaxed.owl FYPO:0003279 biolink:NamedThing excess Golgi cisternae present A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more Golgi cisternae than normal. Golgi cisternae are the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex. FYPO_relaxed.owl FYPO:0006433 biolink:NamedThing abnormal tubular endoplasmic reticulum morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the tubular endoplasmic reticulum (ER) is abnormal. The tubular ER is the portion of the ER that consists of tubules having membranes with high curvature in cross-section. FYPO_relaxed.owl FYPO:0007572 biolink:NamedThing cortical endoplasmic reticulum detached from plasma membrane A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the cortical endoplasmic reticulum (ER) is dissociated from the plasma membrane. Normally, cortical ER tubules are closely juxtaposed to the plasma membrane. FYPO_relaxed.owl FYPO:0008139 biolink:NamedThing dilated endoplasmic reticulum lumen A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the endoplasmic reticulum lumen is larger than normal. FYPO_relaxed.owl FYPO:0001785 biolink:NamedThing abnormal sterol binding A molecular function phenotype in which occurrence of sterol binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007251 biolink:NamedThing decreased lipid binding A molecular function phenotype in which occurrence of lipid binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001786 biolink:NamedThing abolished sterol binding A molecular function phenotype in which sterol binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007253 biolink:NamedThing abolished membrane lipid binding A molecular function phenotype in which binding to a lipid in a membrane by a gene product does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001787 biolink:NamedThing normal sterol binding A molecular function phenotype in which occurrence of sterol binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007528 biolink:NamedThing normal membrane lipid binding A molecular function phenotype in which occurrence of binding to a lipid in a membrane by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001789 biolink:NamedThing normal protein localization to nucleus during cellular response to oxidative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during a cellular response to oxidative stress. FYPO_relaxed.owl FYPO:0002563 biolink:NamedThing normal protein localization to nuclear periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002965 biolink:NamedThing normal protein localization to nucleolus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003132 biolink:NamedThing normal punctate nuclear localization during cellular response to ionizing radiation A cell phenotype in which a gene product is normally localized to discrete regions in the nucleus (i.e. its localization is indistinguishable from wild type), visible as foci or dots by microscopy, during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0004121 biolink:NamedThing normal protein import into nucleus during vegetative growth A transport phenotype observed in the vegetative growth phase of the life cycle in which the import of protein into the nucleus is normal (i.e. indistinguishable from wild type). Import of all proteins or a specific protein may be assayed. FYPO_relaxed.owl FYPO:0004828 biolink:NamedThing normal protein localization to nucleus during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during mitosis. FYPO_relaxed.owl FYPO:0004887 biolink:NamedThing normal protein localization to nuclear envelope during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear envelope is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004910 biolink:NamedThing normal punctate nuclear protein localization A cell phenotype in which a protein that is localized normally (i.e. indistinguishably from wild type) to discrete regions in the nucleus, visible as foci or dots by microscopy. FYPO_relaxed.owl FYPO:0005644 biolink:NamedThing normal protein localization to nucleus during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0005890 biolink:NamedThing normal protein localization to nucleus during cellular response to calcium ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during a cellular response to calcium ions. FYPO_relaxed.owl FYPO:0005907 biolink:NamedThing normal protein localization to nucleus during cellular response to heat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during a cellular response to heat. FYPO_relaxed.owl FYPO:0006125 biolink:NamedThing normal protein localization to nuclear body A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a nuclear body is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006919 biolink:NamedThing normal protein localization to nucleus during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0001798 biolink:NamedThing decreased translation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translation is decreased. FYPO_relaxed.owl FYPO:0003911 biolink:NamedThing UGA suppression A translation phenotype in which a tRNA pairs with mRNA at the stop codon UGA, and incorporates an amino acid residue into the nascent polypeptide. FYPO_relaxed.owl FYPO:0003956 biolink:NamedThing UAA suppression A translation phenotype in which a tRNA pairs with mRNA at the stop codon UAA, and incorporates an amino acid residue into the nascent polypeptide. FYPO_relaxed.owl FYPO:0004528 biolink:NamedThing abnormal mitochondrial translation A metabolism phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial translation is abnormal. FYPO_relaxed.owl FYPO:0006550 biolink:NamedThing decreased gene expression during nitrogen starvation A cellular process phenotype in which gene expression occurs to a lower extent than normal when the cell is subject to nitrogen starvation. One or more parts of gene expression, such as transcription or translation, may be affected, and all genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0001800 biolink:NamedThing abolished protein localization to cell tip, with protein distributed in plasma membrane or cortex A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is abolished, and the protein is instead detected distributed throughout the plasma membrane and/or cell cortex. FYPO_relaxed.owl FYPO:0002859 biolink:NamedThing abolished protein localization to non-growing cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the non-growing cell tip is abolished. The new cell tip formed upon cell division does not grow until after new end take-off. FYPO_relaxed.owl FYPO:0003209 biolink:NamedThing abolished protein localization to cell tip, with protein mislocalized to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is abolished, and the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0003329 biolink:NamedThing abolished protein localization to cell tip during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip does not occur during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005836 biolink:NamedThing abolished protein transport along microtubule to cell tip during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cell tip does not occur. Transport of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0001808 biolink:NamedThing decreased adenine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of adenine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001810 biolink:NamedThing decreased guanine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of guanine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004840 biolink:NamedThing abnormal high-affinity glucose import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which high-affinity import of glucose into the cell is abnormal. FYPO_relaxed.owl FYPO:0008015 biolink:NamedThing decreased glucose import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of glucose into the cell is decreased with respect to wild-type. FYPO_relaxed.owl FYPO:0001836 biolink:NamedThing normal protein localization to spindle pole body A cell phenotype in which the localization of a protein to the spindle pole body is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007866 biolink:NamedThing normal protein localization to meiotic spindle A cell phenotype in which the localization of a protein to the meiotic spindle is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007875 biolink:NamedThing normal protein localization to actin fusion focus A cell phenotype in which the localization of a protein to the actin fusion focus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005034 biolink:NamedThing decreased protein phosphorylation during nitrogen starvation A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a lower extent than normal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0005577 biolink:NamedThing decreased protein phosphorylation during meiotic cell cycle A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a lower extent than normal during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0005749 biolink:NamedThing decreased protein phosphorylation during glucose starvation A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a lower extent than normal when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0001860 biolink:NamedThing increased minichromosome loss during meiotic cell cycle A cell phenotype in which minichromosomes are lost at a higher frequency than normal during the meiotic cell cycle. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation. FYPO_relaxed.owl FYPO:0001846 biolink:NamedThing increased duration of mitotic anaphase A A cellular process phenotype in which the duration of progression through anaphase A of mitosis is longer than normal. Anaphase A is the mitotic cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles. FYPO_relaxed.owl FYPO:0005706 biolink:NamedThing increased duration of mitotic anaphase B A cellular process phenotype in which the duration of progression through anaphase B of mitosis is longer than normal. Anaphase B is the stage of mitosis in which the polar microtubules elongate and the two poles of the spindle move farther apart. FYPO_relaxed.owl FYPO:0001850 biolink:NamedThing decreased ferric iron import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of ferric iron ions into a cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001853 biolink:NamedThing abolished transcription during iron starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription does not occur when the cell is subject to iron ion starvation. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0003796 biolink:NamedThing abolished transcription from RNA polymerase II promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from an RNA polymerase II promoter does not occur. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0003556 biolink:NamedThing abnormal transcription termination A cell phenotype observed in the vegetative growth phase of the life cycle in which the termination of RNA transcription from a DNA template is abnormal. FYPO_relaxed.owl FYPO:0003652 biolink:NamedThing abnormal transcription initiation from RNA polymerase III promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription initiation from an RNA polymerase III promoter is abnormal. FYPO_relaxed.owl FYPO:0004065 biolink:NamedThing abnormal transcription elongation from RNA polymerase II promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the elongation of a transcript initiated from an RNA polymerase II promoter is abnormal. FYPO_relaxed.owl FYPO:0002883 biolink:NamedThing normal transcription during glucose starvation A cellular process phenotype in which transcription occurs to is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc. when the cell is subject to glucose starvation. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0005117 biolink:NamedThing normal transcription during nitrogen starvation A cellular process phenotype in which transcription occurs to is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc. when the cell is subject to nitrogen starvation. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0001856 biolink:NamedThing normal transcription during iron starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent when the cell is subject to iron ion starvation. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0002884 biolink:NamedThing normal transcription during cellular response to osmotic stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to osmotic stress. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0002885 biolink:NamedThing normal transcription during cellular response to oxidative stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to oxidative stress. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0002886 biolink:NamedThing normal transcription during cellular response to heavy metal stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to heavy metal stress. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0002896 biolink:NamedThing normal transcription during cellular response to calcium ion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to calcium ions. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0003036 biolink:NamedThing normal transcription during cellular response to UV A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to ultraviolet light. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0004008 biolink:NamedThing normal rRNA transcription A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription of ribosomal DNA into ribosomal RNA occurs to a normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005740 biolink:NamedThing normal transcription during cellular response to heat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to heat. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0006742 biolink:NamedThing normal transcription from MCB promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more MluI cell cycle box factor elements (MCBs) is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc. FYPO_relaxed.owl FYPO:0006762 biolink:NamedThing normal transcription during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription occurs to a normal (i.e. indistinguishable from wild type) extent during a cellular response to hydroxyurea. All genes, or a specific subset of genes, may be measured. FYPO_relaxed.owl FYPO:0007614 biolink:NamedThing normal transcription from STREP promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more STREP motifs is normal (i.e. indistinguishable from wild type) in extent, timing, start or termination site, etc. FYPO_relaxed.owl FYPO:0001861 biolink:NamedThing increased minichromosome loss upon segregation during vegetative growth A cell phenotype in which minichromosomes are lost due to abnormal mitotic sister chromatid segregation at a higher frequency than normal. FYPO_relaxed.owl FYPO:0005371 biolink:NamedThing increased linear minichromosome loss during vegetative growth A cell phenotype in which linear minichromosomes are lost at a higher frequency than normal during the vegetative growth phase of the life cycle. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation. FYPO_relaxed.owl FYPO:0005372 biolink:NamedThing increased circular minichromosome loss during vegetative growth A cell phenotype in which circular minichromosomes are lost at a higher frequency than normal during the vegetative growth phase of the life cycle. Minichromosome loss occurs when one or both daughter cells do not inherit copies of a minichromosome from the mother cell, and may result from failure of minichromosome replication or segregation. FYPO_relaxed.owl FYPO:0001862 biolink:NamedThing increased minichromosome loss upon segregation during meiotic cell cycle A cell phenotype in which minichromosomes are lost due to abnormal meiotic chromosome segregation at a higher frequency than normal. FYPO_relaxed.owl FYPO:0001876 biolink:NamedThing decreased asymmetric protein localization, with protein localized to both mitotic spindle pole bodies during anaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the preferential localization of a protein to either the old or new spindle pole body is decreased during mitotic anaphase, and the protein is instead symmetrically localized to both SPBs. FYPO_relaxed.owl FYPO:0001883 biolink:NamedThing normal growth on caspofungin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing caspofungin. FYPO_relaxed.owl FYPO:0002160 biolink:NamedThing normal growth on cilofungin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing cilofungin. FYPO_relaxed.owl FYPO:0002940 biolink:NamedThing normal growth on micafungin A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing micafungin. FYPO_relaxed.owl FYPO:0001885 biolink:NamedThing decreased protein phosphorylation during salt stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal when the cell is subject to salt stress. FYPO_relaxed.owl FYPO:0002376 biolink:NamedThing decreased protein phosphorylation during cellular response to osmotic stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to osmotic stress. FYPO_relaxed.owl FYPO:0001886 biolink:NamedThing meiotic cell cycle entry and sporulation in haploid A cellular process phenotype in which haploid cells undergo meiotic nuclear division and attempt to sporulate. Haploid meiosis often results in the formation of a structure that resembles an azygotic ascus. Spores produced from a haploid cell have poor viability and appear to contain only 1/2C DNA on average. FYPO_relaxed.owl FYPO:0009006 biolink:NamedThing abnormal meiotic cell cycle entry A cellular process phenotype in which a cell enters the meiotic cell cycle without either of the normal steps that precede it: conjugation with cellular fusion and karyogamy with nuclear fusion. FYPO_relaxed.owl FYPO:0003061 biolink:NamedThing meiotic cell cycle in zygote with unfused nuclei A cellular process phenotype in which the two nuclei in a zygote formed by conjugation with cellular fusion undergo meiosis before karyogamy with nuclear fusion is completed. FYPO_relaxed.owl FYPO:0006670 biolink:NamedThing meiotic cell cycle entry in haploid cell A cellular process phenotype in which a haploid cell undergoes meiotic cell cycle. FYPO_relaxed.owl FYPO:0001891 biolink:NamedThing increased level of middle meiotic gene mRNA during late meiosis A cell phenotype observed in late meiosis in which the amount of RNA transcribed from middle meiotic genes measured in a cell is higher than normal. Middle meiotic genes are normally transcribed during meiotic nuclear division. FYPO_relaxed.owl FYPO:0005124 biolink:NamedThing increased level of early meiotic gene mRNA during late meiosis A cell phenotype observed in late meiosis in which the amount of RNA transcribed from early meiotic genes measured in a cell is higher than normal. Early meiotic genes are normally transcribed during pre-meiotic S phase and recombination. FYPO_relaxed.owl FYPO:0005125 biolink:NamedThing increased level of nitrogen starvation gene mRNA during meiotic cell cycle A cell phenotype in which the amount of one or more RNAs that are normally expressed during nitrogen starvation measured in a cell is higher than normal (i.e. higher than observed in wild-type cells) during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0005126 biolink:NamedThing increased level of carbohydrate metabolism gene mRNA during meiotic cell cycle A cell phenotype in which the amount of one or more carbohydrate metabolism RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells) during the meiotic cell cycle. Carbohydrate metabolism RNAs are transcribed from genes whose products are involved in carbohydrate metabolic processes. FYPO_relaxed.owl FYPO:0001892 biolink:NamedThing decreased level of middle meiotic gene mRNA during late meiosis A cell phenotype observed in late meiosis in which the amount of RNA transcribed from middle meiotic genes measured in a cell is lower than normal. Middle meiotic genes are normally transcribed during meiotic nuclear division. FYPO_relaxed.owl FYPO:0002959 biolink:NamedThing decreased RNA level during meiosis A cell phenotype in which the amount of RNA measured in a cell is lower than normal during one or both meiotic nuclear divisions. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004937 biolink:NamedThing decreased RNA level during meiosis I A cell phenotype in which the amount of RNA measured in a cell is lower than normal during the first meiotic nuclear division. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0006975 biolink:NamedThing RNA absent from cell during meiotic cell cycle A cell phenotype in which the amount of RNA measured in a cell is too low to detect during the meiotic cell cycle. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0008141 biolink:NamedThing decreased RNA level during meiosis II A cell phenotype in which the amount of RNA measured in a cell is lower than normal during the second meiotic nuclear division. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0001893 biolink:NamedThing abnormal sporulation resulting in formation of azygotic ascus with more or fewer than four spores A sporulation phenotype in which azygotic asci that contain more or fewer than four spores form following conjugation, diploid growth, and subsequent azygotic sporulation. Azygotic ascus formation occurs when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell. FYPO_relaxed.owl FYPO:0003263 biolink:NamedThing abnormal sporulation resulting in formation of ascus with more than four spores A sporulation phenotype in which asci that contain more than four, and up to eight, spores form following conjugation and subsequent sporulation. FYPO_relaxed.owl FYPO:0001899 biolink:NamedThing P-bodies present in decreased numbers during glucose starvation A physical cellular phenotype in which cells contain fewer cytoplasmic mRNA processing bodies (P-bodies) than normal when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0001902 biolink:NamedThing small P-bodies during glucose starvation A physical cellular phenotype in which cytoplasmic mRNA processing bodies (P-bodies) are smaller than normal when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0001911 biolink:NamedThing decreased protein glycosylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the glycosylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid. FYPO_relaxed.owl FYPO:0002447 biolink:NamedThing abnormal protein N-linked glycosylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the N-glycosylation of one or more specific proteins, or of specific protein sites, is abnormal. Protein N-linked glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan. FYPO_relaxed.owl FYPO:0007032 biolink:NamedThing increased protein glycosylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the glycosylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid. FYPO_relaxed.owl FYPO:0008051 biolink:NamedThing decreased ubiquitin ligase activity A molecular function phenotype in which the observed rate of ubiquitin ligase activity is decreased. FYPO_relaxed.owl FYPO:0006056 biolink:NamedThing prospore formation with spindle pole body dissociated from prospore membrane A cellular process phenotype in which the spindle pole body does not attach to the prospore membrane during prospore membrane formation and closure. Normally, the prospore membrane associates with the spindle pole body from late anaphase of meiosis II until the membrane has completely closed. FYPO_relaxed.owl FYPO:0006778 biolink:NamedThing prospore formation with septin ring dissociated from prospore membrane A cellular process phenotype in which the septin ring does not associate with the prospore membrane during prospore membrane formation and closure. Normally, the septin ring forms in close association with the assembling prospore membrane. FYPO_relaxed.owl FYPO:0007605 biolink:NamedThing decreased outer prospore membrane breakdown A cellular process phenotype in which breakdown of the outer layer of the prospore membrane (forespore membrane; FSM) is decreased. Normally, the outer of the two FSM layers breaks down completely, producing a mature spore. When FSM breakdown does not occur normally, the outer FSM layers of two adjacent spores may be fused. FYPO_relaxed.owl FYPO:0004933 biolink:NamedThing increased prospore membrane formation A cellular process phenotype in which prospore membrane formation is increased. FYPO_relaxed.owl FYPO:0004952 biolink:NamedThing incomplete prospore membrane closure A cellular process phenotype in which the prospore membrane begins to form and enclose the nucleus, but the leading edge does not close completely, leaving a gap in the membrane. FYPO_relaxed.owl FYPO:0005736 biolink:NamedThing decreased prospore membrane formation A cellular process phenotype in which prospore membrane formation is decreased. FYPO_relaxed.owl FYPO:0005737 biolink:NamedThing delayed onset of prospore membrane formation A cellular process phenotype in which prospore membrane formation begins later than normal. FYPO_relaxed.owl FYPO:0006051 biolink:NamedThing decreased lipid droplet localization to prospore membrane leading edge A cellular process phenotype in which the localization of lipid droplets to the prospore membrane occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006777 biolink:NamedThing prospore membrane formation excluding nucleus A cellular process phenotype in which the prospore membrane forms, and may complete closure, without enclosing a nucleus; one or more nuclei may be present in the ascus, not enclosed by any prospore membrane. FYPO_relaxed.owl FYPO:0006339 biolink:NamedThing mononucleate vegetative cell with mislocalized nucleus A cell phenotype in which a cell has one nucleus that is not in the normal location. FYPO_relaxed.owl FYPO:0004673 biolink:NamedThing inviable elongated multiseptate vegetative cell with fragmented nucleus A cell morphology phenotype in which a vegetatively growing cell is inviable, is elongated, contains more than one septum, and contains a nucleus that is broken into small fragments. FYPO_relaxed.owl FYPO:0004929 biolink:NamedThing fragmented nucleus during meiotic cell cycle A cell phenotype in which the nucleus is broken into multiple small fragments, smaller than a normal nucleus, during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0006662 biolink:NamedThing fragmented nucleus during G0 A cell phenotype observed during G0 phase in which the nucleus is broken into multiple small fragments that are smaller than a normal nucleus. FYPO_relaxed.owl FYPO:0007618 biolink:NamedThing delayed onset of protein export from nucleus A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of protein from the nucleus begins later than normal. Export of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0002522 biolink:NamedThing decreased poly(A)+ mRNA export from nucleus A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of polyadenylated mRNA from the nucleus is decreased. Export of all polyadenylated mRNAs or a specific mRNA may be affected. FYPO_relaxed.owl FYPO:0001923 biolink:NamedThing normal protein dephosphorylation during mitotic G2/M transition A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein dephosphorylation is normal (i.e. indistinguishable from wild type) during the G2/M phase transition of the mitotic cell cycle. Protein dephosphorylation is the removal of a phosphate group from a protein amino acid. FYPO_relaxed.owl FYPO:0007893 biolink:NamedThing normal protein dephosphorylation during mitotic exit A cellular process phenotype in which protein dephosphorylation is normal during mitotic exit (i.e. indistinguishable from wild type). Protein dephosphorylation is the removal of a phosphate group from a protein amino acid. FYPO_relaxed.owl FYPO:0001931 biolink:NamedThing abnormal mitotic cell cycle regulation during cellular response to gamma radiation A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to gamma radiation is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to gamma radiation. The most common abnormality is for the cell cycle to progress as in the absence of gamma radiation. FYPO_relaxed.owl FYPO:0003490 biolink:NamedThing increased duration of mitotic DNA damage checkpoint during cellular response to ionizing radiation A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0004551 biolink:NamedThing abnormal mitotic cell cycle regulation during cellular response to ionizing radiation during mitotic S phase A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ionizing radiation exposure during mitotic S phase is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to ionizing radiation. The most common abnormality is for the cell cycle to progress as in the absence of ionizing radiation. FYPO_relaxed.owl FYPO:0007248 biolink:NamedThing decreased duration of mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by the mitotic G2 DNA damage checkpoint is shorter than in wild type during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0002118 biolink:NamedThing decreased transporter activity A molecular function phenotype in which the observed rate of a specified transporter activity is decreased. FYPO_relaxed.owl FYPO:0002119 biolink:NamedThing increased transporter activity A molecular function phenotype in which the observed rate of a specified transporter activity is increased. FYPO_relaxed.owl FYPO:0002121 biolink:NamedThing abnormal sodium:hydrogen antiporter activity A molecular function phenotype in which the observed rate of sodium:hydrogen antiporter activity is abnormal. FYPO_relaxed.owl FYPO:0001944 biolink:NamedThing abolished microtubule binding A molecular function phenotype in which microtubule binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003425 biolink:NamedThing abolished protein-protein interaction during cellular response to rapamycin A molecular function phenotype in which the binding of one protein to another does not occur during a cellular response to rapamycin. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0004232 biolink:NamedThing abolished methylated histone binding A molecular function phenotype in which methylated histone binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006025 biolink:NamedThing abolished actin filament binding A molecular function phenotype in which the binding of a protein to one or more actin filaments does not occur. The affected protein may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006066 biolink:NamedThing abolished tubulin heterodimer binding A molecular function phenotype in which the binding of a protein to one or more alpha/beta tubulin heterodimers does not occur. The affected protein may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007077 biolink:NamedThing abolished ubiquitin binding A molecular function phenotype in which binding to ubiquitin by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007132 biolink:NamedThing increased microtubule binding A molecular function phenotype in which the binding of a protein to one or more microtubules occurs to a greater extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0001945 biolink:NamedThing normal protein secretion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein secretion is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005397 biolink:NamedThing normal intracellular protein transport during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0001949 biolink:NamedThing increased cytosolic calcium level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in the cytosol is higher than normal. FYPO_relaxed.owl FYPO:0006828 biolink:NamedThing increased cytosolic zinc level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in the cytosol is higher than normal. FYPO_relaxed.owl FYPO:0007292 biolink:NamedThing increased cytosolic UDP-galactose level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of UDP-galactose measured in the cytosol is higher than normal. FYPO_relaxed.owl FYPO:0001952 biolink:NamedThing decreased calcium export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of calcium ions out of a cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0001954 biolink:NamedThing decreased calcium import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of calcium ions into a cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004203 biolink:NamedThing increased calcium import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of calcium ions into a cell occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0002166 biolink:NamedThing abolished polynucleotide 3'-phosphatase activity A molecular function phenotype in which polynucleotide 3'-phosphatase activity is absent. FYPO_relaxed.owl FYPO:0004299 biolink:NamedThing abolished polynucleotide 5'-phosphatase activity A molecular function phenotype in which polynucleotide 5'-phosphatase activity is absent. FYPO_relaxed.owl FYPO:0005485 biolink:NamedThing abolished inositol phosphate phosphatase activity A molecular function phenotype in which an inositol phosphate phosphatase activity is absent. FYPO_relaxed.owl FYPO:0007043 biolink:NamedThing abolished alkaline phosphatase activity A molecular function phenotype in which alkaline phosphatase activity is absent. FYPO_relaxed.owl FYPO:0001968 biolink:NamedThing increased 1,3-beta-D-glucan synthase activity A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is increased. FYPO_relaxed.owl FYPO:0004894 biolink:NamedThing decreased 1,3-beta-D-glucan synthase activity during sporulation A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is decreased during sporulation. FYPO_relaxed.owl FYPO:0001969 biolink:NamedThing increased 1,3-beta-D-glucan synthase activity during growth on papulacandin B A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is increased when cells are grown in medium containing papulacandin B. FYPO_relaxed.owl FYPO:0001970 biolink:NamedThing increased 1,3-beta-D-glucan synthase activity during growth on aculeacin A A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is increased when cells are grown in medium containing aculeacin A. FYPO_relaxed.owl FYPO:0007810 biolink:NamedThing normal cytoplasmic microtubules during cellular response to pheromone A physical cellular phenotype in which the amount, distribution, and morphology of cytoplasmic microtubules is normal (i.e. indistinguishable from wild type) during a cellular response to a pheromone. FYPO_relaxed.owl FYPO:0003537 biolink:NamedThing decreased rate of premeiotic DNA replication A cellular process phenotype in which the rate, or speed, of premeiotic DNA replication is decreased. FYPO_relaxed.owl FYPO:0003923 biolink:NamedThing decreased rate of mitotic DNA replication elongation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA strand elongation involved in mitotic nuclear DNA replication is decreased. FYPO_relaxed.owl FYPO:0001992 biolink:NamedThing inviable elongated mononucleate vegetative cell with mislocalized septum A cell phenotype in which a cell contains a single septum, has one nucleus, is elongated, and is inviable. The septum is in an abnormal location, and the nucleus is located in one compartment of the septated cell. FYPO_relaxed.owl FYPO:0002252 biolink:NamedThing inviable swollen elongated mononucleate vegetative cell with normally localized septum A cell phenotype in which a cell contains a single septum, has one nucleus, is elongated, and is inviable. The septum is in an abnormal location, and the nucleus is located in one compartment of the septated cell. The cell compartment containing the nucleus is swollen (i.e. has a larger diameter and volume than the other compartment). FYPO_relaxed.owl FYPO:0002076 biolink:NamedThing inviable elongated cell with fragmented nucleus and increased septum thickness A cell phenotype in which a cell is elongated, has a nucleus that is broken into multiple small fragments, forms a septum that is thicker than normal, and is inviable. FYPO_relaxed.owl FYPO:0001994 biolink:NamedThing inviable swollen elongated mononucleate vegetative cell with mislocalized septum near new end A cell phenotype in which a cell contains a single septum, has one nucleus, is swollen, is elongated, and is inviable. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. The septum is in an abnormal location, and the nucleus is located in one compartment of the septated cell. The cell compartment containing the nucleus is swollen (i.e. has a larger diameter than the other compartment). FYPO_relaxed.owl FYPO:0006946 biolink:NamedThing inviable swollen elongated multiseptate vegetative cell A cell morphology phenotype in which a vegetative cell is inviable, is swollen, is elongated, and contains more than one septum. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0001996 biolink:NamedThing RNA absent from cell during nitrogen starvation A cell phenotype in which the amount of RNA measured in a cell is too low to detect when the cell is subject to nitrogen starvation. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004176 biolink:NamedThing decreased RNA level during cellular response to pheromone and nitrogen starvation A cell phenotype in which the amount of RNA measured in a cell during a cellular response to a pheromone that occurs when the cell is subject to nitrogen starvation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004460 biolink:NamedThing decreased level of regulation of mitotic cell cycle gene mRNA during nitrogen starvation A cell phenotype in which the amount of one or more regulation of mitotic cell cycle RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells) when the cell is subject to nitrogen starvation. Regulation of mitotic cell cycle RNAs are transcribed from genes whose products are involved in regulation of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004461 biolink:NamedThing decreased level of regulation of sexual differentiation gene mRNA during nitrogen starvation A cell phenotype in which the amount of one or more regulation of sexual differentiation RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells) when the cell is subject to nitrogen starvation. Sexual differentiation RNAs are transcribed from genes whose products are involved in sexual differentiation, i.e. mating and sporulation. FYPO_relaxed.owl FYPO:0002585 biolink:NamedThing mature mitochondrial tRNA absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature mitochondrial transfer RNA (tRNA) measured in a cell is too low to detect. Total tRNA or a specific tRNA may be affected. FYPO_relaxed.owl FYPO:0004072 biolink:NamedThing RNA absent from cell during cellular response to pheromone A cell phenotype in which the amount of RNA measured in a cell is too low to detect during a cellular response to a pheromone. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002000 biolink:NamedThing inviable septated mononucleate vegetative cell A cell phenotype in which a cell is inviable, and contains one nucleus and one or more septa. The nucleus is not in the normal location. FYPO_relaxed.owl FYPO:0002007 biolink:NamedThing abnormal chromosome morphology, single irregular mass A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which chromosomes form a single, irregularly-shaped mass in the nucleus. FYPO_relaxed.owl FYPO:0002702 biolink:NamedThing circularized chromosome A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which one or more chromosomes forms a circle by fusion of its ends. FYPO_relaxed.owl FYPO:0003766 biolink:NamedThing aggregated mtDNA A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial DNA molecules are interlinked by unresolved recombination junctions. FYPO_relaxed.owl FYPO:0004515 biolink:NamedThing abnormal chromosome morphology, indistinct DNA A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which DNA is not visible in a distinct structure corresponding to the nucleus, but is instead diffuse or not visible at all. FYPO_relaxed.owl FYPO:0005404 biolink:NamedThing telomeric regions absent from linear chromosomes A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which chromosomes remain linear, but lose telomeric repeats. Subtelomeric DNA may also be lost. FYPO_relaxed.owl FYPO:0005778 biolink:NamedThing abnormal chromosome morphology during cellular response to acetaldehyde A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of one or more chromosomes is abnormal during a cellular response to acetaldehyde. FYPO_relaxed.owl FYPO:0007512 biolink:NamedThing abnormal chromosome III morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure chromosome III is abnormal. FYPO_relaxed.owl FYPO:0002019 biolink:NamedThing elongated telomeres during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form telomeres that are longer than normal. FYPO_relaxed.owl FYPO:0006464 biolink:NamedThing abnormal telomere length during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which telomere length is abnormal. FYPO_relaxed.owl FYPO:0002239 biolink:NamedThing shortened telomeres during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form telomeres that are shorter than normal. FYPO_relaxed.owl FYPO:0006166 biolink:NamedThing inviable branched, swollen, elongated, multinucleate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, branched, has more than one nucleus, and has a larger volume and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0006556 biolink:NamedThing inviable elongated tetranucleate triseptate vegetative cell, single septa between nuclei A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is elongated, has four nuclei and three septa, and the septa are not grouped together, but are located so as to form separate compartments with a single nucleus in each. FYPO_relaxed.owl FYPO:0002050 biolink:NamedThing branched elongated multinucleate aseptate vegetative cell A cell morphology phenotype in which vegetative a cell is branched, elongated, has no septum, and contains more than one nucleus. FYPO_relaxed.owl FYPO:0002051 biolink:NamedThing swollen elongated multinucleate aseptate vegetative cell A cell morphology phenotype in which a vegetative cell is swollen, elongated, has no septum, and contains more than one nucleus. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0005689 biolink:NamedThing inviable binucleate aseptate cell with mitotic cell cycle arrest before cell separation A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable and has two nuclei but no septum, and the mitotic cell cycle is arrested before cell separation takes place. FYPO_relaxed.owl FYPO:0002026 biolink:NamedThing actomyosin contractile ring displaced from midpoint A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms an actomyosin contractile ring that is perpendicular to the long axis of the cell, but is not located at the midpoint of the long axis. FYPO_relaxed.owl FYPO:0002027 biolink:NamedThing angled actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms an actomyosin contractile ring that is not perpendicular to the long axis of the cell. FYPO_relaxed.owl FYPO:0002436 biolink:NamedThing misoriented actin cables A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the orientation of actin cables within a cell is abnormal. FYPO_relaxed.owl FYPO:0003315 biolink:NamedThing actin cables absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable actin cables. FYPO_relaxed.owl FYPO:0002032 biolink:NamedThing abnormal actin cable morphology during mitosis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of actin cables is abnormal during mitosis. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts. FYPO_relaxed.owl FYPO:0002434 biolink:NamedThing short actin cables A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin cables that are shorter than normal. FYPO_relaxed.owl FYPO:0002437 biolink:NamedThing thick actin cables A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin cables that are thicker than normal. FYPO_relaxed.owl FYPO:0007151 biolink:NamedThing long actin cables A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin cables that are longer than normal. FYPO_relaxed.owl FYPO:0007996 biolink:NamedThing thin actin cables A physical cellular phenotype observed in mitotic interphase in which cells form actin cables that are thinner than normal. This is evidence by lower actin fluorescence signal and is likely due to the presence of fewer actin filaments than normal. FYPO_relaxed.owl FYPO:0004939 biolink:NamedThing abolished protein phosphorylation during meiotic cell cycle A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0005036 biolink:NamedThing abolished protein phosphorylation during nitrogen starvation A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006708 biolink:NamedThing abolished protein phosphorylation during glucose starvation A cellular process phenotype in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0003239 biolink:NamedThing abnormal phosphodiesterase I activity A molecular function phenotype in which the observed rate of phosphodiesterase I activity is abnormal. FYPO_relaxed.owl FYPO:0003821 biolink:NamedThing abnormal ribonuclease activity A molecular function phenotype in which the observed rate of a ribonuclease activity is abnormal. FYPO_relaxed.owl FYPO:0002037 biolink:NamedThing decreased endodeoxyribonuclease activity A molecular function phenotype in which the observed rate of an endodeoxyribonuclease activity is decreased. FYPO_relaxed.owl FYPO:0003666 biolink:NamedThing abnormal crossover junction endodeoxyribonuclease activity A molecular function phenotype in which the observed rate of crossover junction endodeoxyribonuclease activity is abnormal. FYPO_relaxed.owl FYPO:0004028 biolink:NamedThing abnormal 5' deoxyribonuclease (pyrimidine dimer) activity A molecular function phenotype in which the observed rate of 5' deoxyribonuclease (pyrimidine dimer) activity is abnormal. FYPO_relaxed.owl FYPO:0007141 biolink:NamedThing abolished endodeoxyribonuclease activity A molecular function phenotype in which an endodeoxyribonuclease activity is absent. FYPO_relaxed.owl FYPO:0002493 biolink:NamedThing decreased DNA 5'-adenosine monophosphate hydrolase activity A molecular function phenotype in which the observed rate of DNA 5'-adenosine monophosphate hydrolase activity is decreased. FYPO_relaxed.owl FYPO:0003240 biolink:NamedThing decreased phosphodiesterase I activity A molecular function phenotype in which the observed rate of phosphodiesterase I activity is decreased. FYPO_relaxed.owl FYPO:0003822 biolink:NamedThing decreased ribonuclease activity A molecular function phenotype in which the observed rate of a ribonuclease activity is decreased. FYPO_relaxed.owl FYPO:0005891 biolink:NamedThing decreased nuclease activity during nitrogen starvation A molecular function phenotype in which the observed rate of a nuclease activity is decreased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0007845 biolink:NamedThing increased rate of RNA catabolic process during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of an RNA catabolic process is increased. FYPO_relaxed.owl FYPO:0002039 biolink:NamedThing decreased deadenylation-independent decapping of nuclear-transcribed mRNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of deadenylation-independent decapping of nuclear-transcribed mRNA is decreased. All RNA decapping may be decreased, or one or more specific RNA molecules may be selectively affected. FYPO_relaxed.owl FYPO:0002040 biolink:NamedThing increased deadenylation-independent decapping of nuclear-transcribed mRNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of deadenylation-independent decapping of nuclear-transcribed mRNA is increased. All RNA decapping may be increased, or one or more specific RNA molecules may be selectively affected. FYPO_relaxed.owl FYPO:0002056 biolink:NamedThing decreased mitochondrial translation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial translation is decreased. FYPO_relaxed.owl FYPO:0003125 biolink:NamedThing decreased cytoplasmic translational initiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translational initiation in the cytoplasm is decreased. FYPO_relaxed.owl FYPO:0004010 biolink:NamedThing decreased translation of ribosomal proteins during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translation of one or more ribosomal proteins is decreased. FYPO_relaxed.owl FYPO:0006445 biolink:NamedThing decreased translation of amino acid biosynthesis proteins during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translation of one or more proteins involved in amino acid biosynthesis is decreased. FYPO_relaxed.owl FYPO:0007317 biolink:NamedThing decreased cytoplasmic translation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translation in the cytoplasm is decreased. FYPO_relaxed.owl FYPO:0002061 biolink:NamedThing inviable vegetative cell population A cell population phenotype in which all cells in the population are inviable in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0002150 biolink:NamedThing inviable spore population A cell population phenotype in which none of the cells in a population of spores are viable. Inviable spores do not germinate. FYPO_relaxed.owl FYPO:0002063 biolink:NamedThing abnormal 3'-5'-exoribonuclease activity A molecular function phenotype in which the observed rate of a 3'-5'-exoribonuclease activity is abnormal. FYPO_relaxed.owl FYPO:0006301 biolink:NamedThing abolished ribonuclease activity A molecular function phenotype in which a ribonuclease activity is absent. FYPO_relaxed.owl FYPO:0007681 biolink:NamedThing abnormal RNA-DNA hybrid ribonuclease activity A molecular function phenotype in which the observed rate or other catalytic property of a RNA-DNA hybrid ribonuclease activity is abnormal. FYPO_relaxed.owl FYPO:0002064 biolink:NamedThing abolished 3'-5'-exoribonuclease activity A molecular function phenotype in which a 3'-5'-exoribonuclease activity is absent. FYPO_relaxed.owl FYPO:0006787 biolink:NamedThing abnormal poly(A)-specific ribonuclease activity A molecular function phenotype in which the observed rate of poly(A)-specific ribonuclease activity is abnormal. FYPO_relaxed.owl FYPO:0008056 biolink:NamedThing abolished poly(A)-specific ribonuclease activity A molecular function phenotype in which a poly(A)-specific ribonuclease activity is absent. FYPO_relaxed.owl FYPO:0002067 biolink:NamedThing slow cell population growth during recovery from stationary phase A cell population phenotype in which a cell population grows more slowly than normal when the population has been in stationary phase and is then placed in conditions that allow recovery. FYPO_relaxed.owl FYPO:0005444 biolink:NamedThing slow vegetative cell population growth followed by return to normal growth rate A cell population phenotype in which vegetative cell population growth is initially slower than normal, and remains slow for several generations, after which the population resumes growing at a normal or near-normal rate. FYPO_relaxed.owl FYPO:0002072 biolink:NamedThing mislocalized nucleus in prospore A physical cellular phenotype in which a prospore has a nucleus in an abnormal location. The normal location is at the midpoint of the long axis of the cell. FYPO_relaxed.owl FYPO:0002802 biolink:NamedThing nucleus mislocalized to cell cortex during nitrogen starvation A physical cellular phenotype in which a cell has a nucleus in an abnormal location at the cell cortex when the cell is subject to nitrogen starvation. The normal location is at the midpoint of the long axis of the cell. FYPO_relaxed.owl FYPO:0003364 biolink:NamedThing mislocalized nucleus during mating A physical cellular phenotype in which a cell has a nucleus in an abnormal location during mating. The normal location of a single nucleus is at the midpoint of the long axis of the cell during vegetative growth, and during mating, the nucleus migrates towards the mating projection. FYPO_relaxed.owl FYPO:0007817 biolink:NamedThing mislocalized nucleus during G0 A physical cellular phenotype in which a cell has a nucleus in an abnormal location during G0 phase. The normal location is at the midpoint of the long axis of the cell. FYPO_relaxed.owl FYPO:0005873 biolink:NamedThing increased secondary cell septum thickness A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a secondary septum that is thicker than normal. FYPO_relaxed.owl FYPO:0004197 biolink:NamedThing inviable elongated cell with fragmented nucleus and mitotic cell cycle arrest in interphase A cell morphology phenotype in which a vegetative cell is inviable and elongated, has a nucleus that is broken into multiple small fragments, and progression through the mitotic cell cycle is arrested in interphase. The cell contains no septum. FYPO_relaxed.owl FYPO:0002078 biolink:NamedThing sensitive to calcium during cellular hypotonic response A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to calcium during a cellular hypotonic response. Cells stop growing (and may die) at a concentration of calcium ions that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002080 biolink:NamedThing sensitive to TPCK A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to N-tosyl-L-phenylalanyl chloromethyl ketone (TPCK). Cells stop growing (and may die) at a concentration of TPCK that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002083 biolink:NamedThing inviable swollen elongated cell with enlarged nucleus A cell morphology phenotype in which a vegetative cell is inviable, is swollen, is elongated, and in which the nucleus is larger than normal. The cell contains one nucleus and no septum. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0007140 biolink:NamedThing inviable after spore germination, multiple cell divisions, swollen, elongated cell A phenotype in which a spore germinates to produce a cell that has a greater length, diameter, volume, and length:diameter ratio than normal, and undergoes two or more rounds of cell division and then dies. FYPO_relaxed.owl FYPO:0002086 biolink:NamedThing exocytic vesicles present in increased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more exocytic vesicles than normal. FYPO_relaxed.owl FYPO:0002087 biolink:NamedThing exocytic vesicles present in increased numbers at cell tip during mitotic interphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more exocytic vesicles at one or both cell tips than normal during interphase of the mitotic cell cycle, when the cell is growing. FYPO_relaxed.owl FYPO:0002088 biolink:NamedThing exocytic vesicles present in increased numbers at septum during septum assembly A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more exocytic vesicles than normal near the division septum while the cell is undergoing septum assembly. FYPO_relaxed.owl FYPO:0002655 biolink:NamedThing enlarged exocytic vesicles present in increased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more exocytic vesicles than normal, and the vesicles are larger than normal. FYPO_relaxed.owl FYPO:0007874 biolink:NamedThing decreased exocytosis at shmoo tip A cellular process phenotype in which exocytosis occurs to a lower extent than normal at the shmoo tip. FYPO_relaxed.owl FYPO:0007987 biolink:NamedThing decreased rate of spindle elongation during meiotic anaphase B A cellular process phenotype in which the rate, or speed, of meiotic spindle elongation is decreased during anaphase B. FYPO_relaxed.owl FYPO:0002093 biolink:NamedThing decreased meiotic sister chromatid cohesion A cellular process phenotype in which cohesion between sister chromatids is decreased during meiosis. FYPO_relaxed.owl FYPO:0004666 biolink:NamedThing decreased meiotic sister chromatid cohesion along chromosome arms A cellular process phenotype in which cohesion between sister chromatids is decreased along the length of the chromosome arms during meiosis. FYPO_relaxed.owl FYPO:0007759 biolink:NamedThing increased duration of meiotic sister chromatid cohesion at centromere during meiosis I A cellular process phenotype in which cohesion between sister chromatids lasts longer than normal in centromeric regions, continuing into anaphase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0002097 biolink:NamedThing decreased protein kinase activity during cellular response to hydroxyurea A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0003331 biolink:NamedThing decreased protein kinase activity during mitotic interphase A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0003836 biolink:NamedThing decreased RNA polymerase II carboxy-terminal domain kinase activity A molecular function phenotype in which the observed rate of RNA polymerase II carboxy-terminal domain kinase activity is decreased. FYPO_relaxed.owl FYPO:0004172 biolink:NamedThing decreased protein kinase activity during cellular response to heat A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during a cellular response to heat. FYPO_relaxed.owl FYPO:0004243 biolink:NamedThing decreased protein kinase activity during cellular response to DNA damage A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0004264 biolink:NamedThing decreased cAMP-dependent protein kinase activity A molecular function phenotype in which the observed rate of cAMP-dependent protein kinase activity is decreased. FYPO_relaxed.owl FYPO:0004633 biolink:NamedThing decreased protein kinase activity during meiosis II A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0005198 biolink:NamedThing decreased protein kinase activity during cellular response to UV A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during a cellular response to ultraviolet light. FYPO_relaxed.owl FYPO:0005269 biolink:NamedThing decreased protein kinase activity during cellular response to hydrogen peroxide A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0005270 biolink:NamedThing decreased protein kinase activity during cellular response to salt stress A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during a cellular response to salt stress. FYPO_relaxed.owl FYPO:0005718 biolink:NamedThing decreased protein kinase activity during mitosis A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during mitosis. FYPO_relaxed.owl FYPO:0008170 biolink:NamedThing decreased cyclin-dependent protein kinase activity A molecular function phenotype in which the observed rate of a cyclin-dependent protein kinase activity is decreased. FYPO_relaxed.owl FYPO:0002098 biolink:NamedThing decreased protein phosphorylation during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0002470 biolink:NamedThing decreased protein phosphorylation during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0002897 biolink:NamedThing decreased protein phosphorylation during cellular response to DNA damage A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to a DNA damage stimulus. FYPO_relaxed.owl FYPO:0002993 biolink:NamedThing decreased protein phosphorylation during cellular response to methyl methanesulfonate A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0003006 biolink:NamedThing decreased protein phosphorylation during cellular response to caffeine A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to caffeine. FYPO_relaxed.owl FYPO:0003298 biolink:NamedThing decreased protein autophosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of autophosphorylation of one or more specific proteins, or of specific protein sites, is decreased. FYPO_relaxed.owl FYPO:0003827 biolink:NamedThing decreased ribosomal S6 protein phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the ribosomal small subunit protein S6 is decreased. FYPO_relaxed.owl FYPO:0004067 biolink:NamedThing decreased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004068 biolink:NamedThing decreased phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 5 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004111 biolink:NamedThing decreased protein phosphorylation during mitotic G2 phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during G2 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004173 biolink:NamedThing decreased protein phosphorylation during cellular response to heat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to heat. FYPO_relaxed.owl FYPO:0004228 biolink:NamedThing decreased protein phosphorylation during cellular response to UV A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to ultraviolet light. FYPO_relaxed.owl FYPO:0004357 biolink:NamedThing decreased protein phosphorylation during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during mitosis. FYPO_relaxed.owl FYPO:0004464 biolink:NamedThing decreased protein phosphorylation during cellular response to camptothecin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to camptothecin. FYPO_relaxed.owl FYPO:0004476 biolink:NamedThing decreased protein phosphorylation during cellular response to calcium ion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to calcium ions. FYPO_relaxed.owl FYPO:0005134 biolink:NamedThing decreased protein phosphorylation during cellular response to micafungin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to micafungin. FYPO_relaxed.owl FYPO:0005479 biolink:NamedThing decreased protein phosphorylation during cellular response to arsenite ion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to arsenite ions. FYPO_relaxed.owl FYPO:0005617 biolink:NamedThing decreased protein phosphorylation during cellular response to bleomycin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to bleomycin. FYPO_relaxed.owl FYPO:0006710 biolink:NamedThing decreased protein phosphorylation during cellular response to alkaline pH A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to a pH above 7. FYPO_relaxed.owl FYPO:0007620 biolink:NamedThing decreased protein phosphorylation during cellular response to oxidative stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal when the cell is subject to oxidative stress. FYPO_relaxed.owl FYPO:0007855 biolink:NamedThing decreased protein phosphorylation during mitotic spindle assembly checkpoint signaling A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during mitotic spindle assembly checkpoint signaling. FYPO_relaxed.owl FYPO:0007908 biolink:NamedThing decreased protein phosphorylation during amino acid starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lesser extent than normal when a cell is subject to amino acid starvation. FYPO_relaxed.owl FYPO:0007811 biolink:NamedThing decreased CMG replicative helicase activity A molecular function phenotype in which the observed rate of CMG replicative helicase activity, the 3'-5' DNA helicase activity that unwinds DNA during nuclear DNA replication, is decreased. FYPO_relaxed.owl FYPO:0005180 biolink:NamedThing normal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ultraviolet light (UV) exposure during mitotic G1 phase is normal (i.e. indistinguishable from wild type). Normally, cell cycle progression is slowed or arrested transiently following exposure to UV. FYPO_relaxed.owl FYPO:0002279 biolink:NamedThing inviable after spore germination, single cell division, with elongated, curved germ tube A phenotype in which a spore germinates to produce an elongated germ tube that is curved along the long axis, and undergoes a single round of cell division. FYPO_relaxed.owl FYPO:0002849 biolink:NamedThing curved cell during recovery from stationary phase A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is curved when the cell population has been in stationary phase and is then placed in conditions that allow recovery. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0004523 biolink:NamedThing inviable after spore germination, single or double cell division, curved, elongated cell A phenotype in which a spore germinates to produce a cell that is elongated and is curved along the long axis, and undergoes one or two rounds of cell division and then dies. FYPO_relaxed.owl FYPO:0005789 biolink:NamedThing C-shaped vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is curved along the long axis to form a "C" shape. In a curved cell, the long axis follows a smooth bend rather than a straight line. In a C-shaped cell, the curve is centered at the midpoint of the long axis of the cell. FYPO_relaxed.owl FYPO:0005790 biolink:NamedThing J-shaped vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is curved along the long axis to form a "J" shape. In a curved cell, the long axis follows a smooth bend rather than a straight line. In a J-shaped cell, the curve is centered away from the midpoint of the long axis of the cell. FYPO_relaxed.owl FYPO:0002120 biolink:NamedThing normal sodium:hydrogen antiporter activity A molecular function phenotype in which the observed rate of sodium:hydrogen antiporter activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002122 biolink:NamedThing decreased sodium:hydrogen antiporter activity A molecular function phenotype in which the observed rate of sodium:hydrogen antiporter activity is decreased. FYPO_relaxed.owl FYPO:0004838 biolink:NamedThing abnormal protein localization to plasma membrane A cell phenotype observed in which the localization of a protein to the plasma membrane is abnormal. FYPO_relaxed.owl FYPO:0006584 biolink:NamedThing abnormal protein localization to shmoo tip membrane A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is abnormal. FYPO_relaxed.owl FYPO:0002126 biolink:NamedThing abolished protein localization to plasma membrane during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is abolished. FYPO_relaxed.owl FYPO:0002127 biolink:NamedThing increased protein localization to plasma membrane during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is increased. FYPO_relaxed.owl FYPO:0005290 biolink:NamedThing decreased protein localization to plasma membrane at cell division site during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell division site is decreased. FYPO_relaxed.owl FYPO:0005544 biolink:NamedThing abnormal protein localization to plasma membrane at cell division site during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell division site is abnormal. FYPO_relaxed.owl FYPO:0008198 biolink:NamedThing decreased protein localization to plasma membrane during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is decreased. FYPO_relaxed.owl FYPO:0004250 biolink:NamedThing abolished protein localization to vacuolar membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuolar membrane is abolished. FYPO_relaxed.owl FYPO:0002130 biolink:NamedThing abolished protein phosphorylation during cellular response to heat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to heat. FYPO_relaxed.owl FYPO:0002289 biolink:NamedThing abolished protein phosphorylation during cellular response to osmotic stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to osmotic stress. FYPO_relaxed.owl FYPO:0002471 biolink:NamedThing abolished protein phosphorylation during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0002898 biolink:NamedThing abolished protein phosphorylation during cellular response to DNA damage A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to a DNA damage stimulus. FYPO_relaxed.owl FYPO:0003020 biolink:NamedThing abolished protein autophosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the autophosphorylation of one or more specific proteins, or of specific protein sites, does not occur. Protein autophosphorylation is the phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. FYPO_relaxed.owl FYPO:0003477 biolink:NamedThing abolished protein phosphorylation during cellular response to arsenic-containing substance A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to an arsenic-containing substance such as arsenate. FYPO_relaxed.owl FYPO:0004069 biolink:NamedThing abolished phosphorylation of RNA polymerase II C-terminal domain serine 2 residues A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II does not occur. FYPO_relaxed.owl FYPO:0004550 biolink:NamedThing abolished protein phosphorylation during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0004659 biolink:NamedThing abolished protein phosphorylation during cellular response to UV A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to ultraviolet light. FYPO_relaxed.owl FYPO:0004660 biolink:NamedThing abolished protein phosphorylation during cellular response to methyl methanesulfonate A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0005366 biolink:NamedThing abolished protein phosphorylation during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during mitosis. FYPO_relaxed.owl FYPO:0005616 biolink:NamedThing abolished protein phosphorylation during cellular response to bleomycin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to bleomycin. FYPO_relaxed.owl FYPO:0006232 biolink:NamedThing abolished protein phosphorylation during cellular response to hydrogen peroxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0006398 biolink:NamedThing abolished protein phosphorylation during cellular response to leucine starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to leucine starvation. FYPO_relaxed.owl FYPO:0006711 biolink:NamedThing abolished protein phosphorylation during cellular response to alkaline pH A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to a pH above 7. FYPO_relaxed.owl FYPO:0007332 biolink:NamedThing abolished increase in protein phosphorylation during cellular response to stress in presence of small molecule A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an increase in the phosphorylation of one or more specific proteins that would normally occur when cells are subjected to a stress in the presence of a specific small molecule does not occur under the same circumstances. FYPO_relaxed.owl FYPO:0002134 biolink:NamedThing decreased protein-RNA interaction A molecular function phenotype in which an interaction between a protein and RNA is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0002135 biolink:NamedThing increased protein-RNA interaction A molecular function phenotype in which an interaction between a protein and RNA is increased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0003552 biolink:NamedThing decreased RNA catabolic process A cellular process phenotype in which the occurrence of an RNA catabolic process is decreased. FYPO_relaxed.owl FYPO:0003553 biolink:NamedThing increased RNA catabolic process A cellular process phenotype in which the occurrence of an RNA catabolic process is increased. FYPO_relaxed.owl FYPO:0002137 biolink:NamedThing decreased RNA catabolic process during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an RNA catabolic process is decreased. FYPO_relaxed.owl FYPO:0005295 biolink:NamedThing decreased RNA catabolic process during nitrogen starvation A cellular process phenotype which the occurrence of an RNA catabolic process is decreased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0007627 biolink:NamedThing decreased RNA catabolic process during glucose starvation A cellular process phenotype which the occurrence of an RNA catabolic process is decreased when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0002138 biolink:NamedThing increased RNA catabolic process during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an RNA catabolic process is increased. FYPO_relaxed.owl FYPO:0003554 biolink:NamedThing increased degradation of middle meiotic gene mRNA during late meiosis A cellular process phenotype in which the occurrence of degradation of RNA transcribed from middle meiotic genes is increased during late meiosis. Middle meiotic genes are normally transcribed during meiotic nuclear division. FYPO_relaxed.owl FYPO:0005892 biolink:NamedThing increased RNA catabolic process during nitrogen starvation A cellular process phenotype in which the occurrence of an RNA catabolic process is increased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0002140 biolink:NamedThing increased cellular pigment accumulation during cellular response to caffeine A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular pigment accumulation is increased during a cellular response to caffeine. FYPO_relaxed.owl FYPO:0002723 biolink:NamedThing increased cellular pigment accumulation during cellular response to cadmium ion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cellular pigment accumulation is increased during a cellular response to cadmium ion. FYPO_relaxed.owl FYPO:0004164 biolink:NamedThing increased cellular reactive oxygen species level in stationary phase A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0002145 biolink:NamedThing normal protein localization to nucleus during cellular response to DEM A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is normal (i.e. indistinguishable from wild type) during a cellular response to diethyl maleate (DEM), a compound which can induce oxidative stress. FYPO_relaxed.owl FYPO:0002155 biolink:NamedThing normal telomere structure during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which chromosome structure is normal (i.e. indistinguishable from wild type) at the telomeric regions. Telomere structure refers to the position, shape, arrangement and connectivity of DNA and associated proteins in the telomeric region. FYPO_relaxed.owl FYPO:0002687 biolink:NamedThing normal telomere length during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which telomere length is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006514 biolink:NamedThing normal telomere structure A physical cellular phenotype in which chromosome structure is normal (i.e. indistinguishable from wild type) at the telomeric regions. Telomere structure refers to the position, shape, arrangement and connectivity of DNA and associated proteins in the telomeric region. FYPO_relaxed.owl FYPO:0006517 biolink:NamedThing normal telomere structure during G0 A physical cellular phenotype in which chromosome structure is normal (i.e. indistinguishable from wild type) at the telomeric regions during G0 phase. Telomere structure refers to the position, shape, arrangement and connectivity of DNA and associated proteins in the telomeric region. FYPO_relaxed.owl FYPO:0002157 biolink:NamedThing normal 1,3-beta-D-glucan synthase activity A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002158 biolink:NamedThing abolished response to mitotic G2/M transition DNA damage checkpoint signaling A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to G2/M transition DNA damage checkpoint signaling does not occur. Abolished arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal. FYPO_relaxed.owl FYPO:0002519 biolink:NamedThing abolished response to mitotic G2/M transition checkpoint signaling A cellular process phenotype in which a cell cycle arrest that normally occurs in response to mitotic G2/M transition cell cycle checkpoint signaling does not occur. Abolished arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal. FYPO_relaxed.owl FYPO:0002159 biolink:NamedThing decreased 1,3-beta-D-glucan synthase activity A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is decreased. FYPO_relaxed.owl FYPO:0002164 biolink:NamedThing mislocalized, curved actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms an actomyosin contractile ring in an abnormal location, and the ring has a curved, or C-shaped, profile. The normal location is at the midpoint of, and perpendicular to, the long axis of the cell. FYPO_relaxed.owl FYPO:0002169 biolink:NamedThing normal growth during cellular response to gamma radiation A cell population growth phenotype in which vegetative cells grow normally (i.e. indistinguishably from wild type) during a cellular response to gamma radiation. FYPO_relaxed.owl FYPO:0002170 biolink:NamedThing inviable after spore germination, multiple cell divisions, branched, elongated cell A phenotype in which a spore germinates to produce a cell that is elongated and branched (and septated), and undergoes two or more rounds of cell division and then dies. FYPO_relaxed.owl FYPO:0002733 biolink:NamedThing inviable after spore germination, multiple cell divisions, elongated tapered cell A phenotype in which a spore germinates to produce a cell that is elongated and tapered, i.e. tapers at one end to a diameter smaller than the other, undergoes two or more rounds of cell division and then dies. FYPO_relaxed.owl FYPO:0003529 biolink:NamedThing inviable after spore germination, multiple cell divisions, cell cycle arrest in mitotic interphase, elongated cells A phenotype in which a spore germinates to produce a cell that enters the cell cycle and undergoes two or more rounds of cell division, but then becomes elongated and undergoes cell cycle arrest in interphase of the mitotic cell cycle, and eventually dies. FYPO_relaxed.owl FYPO:0004119 biolink:NamedThing inviable after spore germination, multiple cell divisions, elongated multinucleate cell with abnormal septum morphology A phenotype in which a spore germinates to produce an inviable cell that is elongated, has more than one nucleus, has one or more septa with abnormal size, shape, or structure, and that undergoes two or more rounds of cell division, and then dies. FYPO_relaxed.owl FYPO:0004120 biolink:NamedThing inviable after spore germination, multiple cell divisions, small cell with abnormal septum morphology A phenotype in which a spore germinates to produce an inviable cell that is smaller than normal, has a septum with abnormal size, shape, or structure, and that undergoes two or more rounds of cell division, and then dies. FYPO_relaxed.owl FYPO:0002174 biolink:NamedThing decreased degradation of DSR-containing RNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an RNA catabolic process that specifically degrades DSR-containing RNA molecules is decreased. A DSR (determinant of selective removal) is a region that is often found near the 3' end of meiosis-specific transcripts, usually contains one or more copies of the motif U(U/C/G)AAAC, and targets RNAs for degradation in vegetatively growing cells. FYPO_relaxed.owl FYPO:0003917 biolink:NamedThing decreased nonsense-mediated decay A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the degradation of messenger RNA (mRNA) molecules that contain nonsense mutations is decreased. FYPO_relaxed.owl FYPO:0006073 biolink:NamedThing decreased small RNA degradation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an RNA catabolic process that specifically degrades small RNA molecules is decreased. FYPO_relaxed.owl FYPO:0006809 biolink:NamedThing decreased nuclear-transcribed mRNA poly(A) tail shortening A cellular process phenotype observed in the vegetative growth phase of the life cycle in which shortening of the poly(A) tail of a messenger RNA (mRNA) molecule is decreased. FYPO_relaxed.owl FYPO:0002429 biolink:NamedThing inviable after spore germination, multiple cell divisions, abnormal cell shape, normal cell size A phenotype in which a spore germinates to produce a cell of abnormal shape and normal size that undergoes two or more rounds of cell division and then dies. FYPO_relaxed.owl FYPO:0002230 biolink:NamedThing inviable swollen curved vegetative cell A cell morphology phenotype in which a vegetatively growing cell is inviable, has a larger volume than normal, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0004965 biolink:NamedThing inviable swollen pear-shaped vegetative cell A cell morphology phenotype in which a cell is inviable, is shaped in the form of a pear, and has a larger volume than normal, in the vegetative growth phase of the life cycle. One end is rounded, while the other resembles an end of a normal rod-shaped cell. The normally shaped end has the same diameter as a wild-type cell. FYPO_relaxed.owl FYPO:0004691 biolink:NamedThing inviable swollen spherical vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is shaped in the form of a sphere, and has a larger volume than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0002208 biolink:NamedThing inviable swollen spore with abnormal shape A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and has a larger volume than normal and an abnormal shape. An inviable spore does not germinate. FYPO_relaxed.owl FYPO:0004535 biolink:NamedThing inviable small spore with abnormal shape A viability phenotype in which a spore is unable to survive under conditions in which wild type spores survive, and has a smaller volume than normal and an abnormal shape. An inviable spore does not germinate. FYPO_relaxed.owl FYPO:0002463 biolink:NamedThing inviable branched, curved, elongated vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, branched, septated, elongated, and is curved along the long axis. FYPO_relaxed.owl FYPO:0002405 biolink:NamedThing viable curved stubby vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable and is curved along the long axis, and the cell diameter is larger than normal and the cell length is shorter than normal. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0004864 biolink:NamedThing viable curved vegetative cell with long curved interphase microtubules A cell morphology phenotype in which a vegetatively growing cell is viable, is curved along the long axis, and contains interphase cytoplasmic microtubules that are longer than normal and curved. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0003677 biolink:NamedThing branched, curved, elongated, multiseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell forms one or more branches near a septum, is elongated, has more than one septum, and is curved along the long axis. FYPO_relaxed.owl FYPO:0002219 biolink:NamedThing normal chromosome disjunction at meiosis I A cellular process phenotype in which homologous chromosome segregation, or disjunction, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003178 biolink:NamedThing normal meiotic sister chromatid segregation A cellular process phenotype in which the organization and subsequent separation of sister chromatids during the second meiotic nuclear division is normal (i.e. indistinguishable from wild type) during meiosis. FYPO_relaxed.owl FYPO:0002221 biolink:NamedThing increased duration of meiotic anaphase II A cellular process phenotype in which the duration of progression through the anaphase of meiosis II is longer than normal. FYPO_relaxed.owl FYPO:0006841 biolink:NamedThing increased duration of meiotic S phase A cellular process phenotype in which the duration of progression through S phase of the meiotic cell cycle (preceding meiosis I) is longer than normal. FYPO_relaxed.owl FYPO:0002222 biolink:NamedThing long meiosis II spindle A spindle phenotype in which the meiotic spindle is longer than normal during meiosis II. FYPO_relaxed.owl FYPO:0007847 biolink:NamedThing long meiosis I spindle A physical cellular phenotype in which the meiotic spindle is longer than normal during meiosis I. FYPO_relaxed.owl FYPO:0002223 biolink:NamedThing abnormal cell cycle arrest in meiosis II A cellular process phenotype in which progression through the meiotic cell cycle is arrested in meiosis II. Meiosis II is the second phase of meiosis, in which cells divide and separate the two chromatids in each chromosome. FYPO_relaxed.owl FYPO:0002817 biolink:NamedThing abnormally arrested meiosis I A cellular process phenotype in which the first meiotic nuclear division is arrested under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0004584 biolink:NamedThing abnormally arrested meiosis I with four spindle pole bodies A cellular process phenotype in which the first meiotic nuclear division is arrested under conditions where arrest does not normally occur, and in which arrested cells contain four spindle pole bodies. Cells may contain one or two spindles, but the nucleus does not divide. FYPO_relaxed.owl FYPO:0005385 biolink:NamedThing abnormal cell cycle arrest in meiotic metaphase I A cellular process phenotype in which progression through the first meiotic nuclear division (part of the meiotic cell cycle) is arrested in metaphase under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0007100 biolink:NamedThing abnormal cell cycle arrest in meiotic prophase I with clustered telomeres A cellular process phenotype in which the first meiotic nuclear division is arrested in prophase I under conditions where arrest does not normally occur, and with telomeres clustered at the spindle pole body. Telomere clustering at the SPB indicates that the cell has reached or passed the pachytene stage. FYPO_relaxed.owl FYPO:0006107 biolink:NamedThing mating, meiosis, and sporulation without starvation A cellular process phenotype in which haploid cells mate and undergo meiotic nuclear division and sporulation in the presence of nutrients, notably nitrogen and glucose. Normally, fission yeast mate, undergo meiosis, and sporulate only under conditions of nitrogen and carbon starvation. FYPO_relaxed.owl FYPO:0006672 biolink:NamedThing transient cell fusion during mating followed by meiotic cell cycle entry and sporulation A cellular process phenotype in which mating cells undergo transient cell fusion (cytogamy), and then one or both cells undergo haploid meiosis and sporulation. In transient cytogamy, cells fuse for a much shorter time than normal during mating, separate with incomplete exchange of cytosol contents, and the conjugation pore then reseals. FYPO_relaxed.owl FYPO:0002246 biolink:NamedThing increased glucose binding A molecular function phenotype in which occurrence of glucose binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002247 biolink:NamedThing decreased glucose binding A molecular function phenotype in which occurrence of glucose binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002248 biolink:NamedThing increased mannose binding A molecular function phenotype in which occurrence of mannose binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002249 biolink:NamedThing decreased fructose binding A molecular function phenotype in which occurrence of fructose binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002873 biolink:NamedThing normal septum orientation A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a septum in the normal orientation perpendicular the long axis of the cell. FYPO_relaxed.owl FYPO:0006509 biolink:NamedThing abnormal telomere length A physical cellular phenotype in which telomere length is abnormal. FYPO_relaxed.owl FYPO:0006510 biolink:NamedThing abnormal telomere structure A physical cellular phenotype in which chromosome structure is abnormal at the telomeric regions. Telomere structure refers to the position, shape, arrangement and connectivity of DNA and associated proteins in the telomeric region. FYPO_relaxed.owl FYPO:0007413 biolink:NamedThing abnormal telomere morphology during G0 A physical cellular phenotype in which the size, shape, or structure of the telomere is abnormal during G0 phase. FYPO_relaxed.owl FYPO:0003701 biolink:NamedThing poly(A)+ RNA-containing focus present in nucleus A physical cellular phenotype in which the nucleus contains one or more foci that are enriched in polyadenylated RNA and are not found in wild-type cells. FYPO_relaxed.owl FYPO:0003874 biolink:NamedThing abnormal dense body present in nucleus during G0 A physical cellular phenotype observed in G0 phase in which the nucleus contains one or more structures of great electron density that are not found in wild type cells. FYPO_relaxed.owl FYPO:0002788 biolink:NamedThing small vacuoles during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are smaller than normal. FYPO_relaxed.owl FYPO:0002789 biolink:NamedThing small vacuoles during stationary phase A cell phenotype observed when the population in which the cell is found is in stationary phase in which vacuoles are smaller than normal. FYPO_relaxed.owl FYPO:0003590 biolink:NamedThing small vacuoles during sporulation A cell phenotype in which vacuoles are smaller than normal during sporulation. FYPO_relaxed.owl FYPO:0002302 biolink:NamedThing inviable after spore germination, multiple cell divisions, spheroid cell A phenotype in which a spore germinates to produce a cell that is spheroid, and undergoes two or more rounds of cell division and then dies. FYPO_relaxed.owl FYPO:0002450 biolink:NamedThing inviable after spore germination, multiple cell divisions, septated cell with abnormal morphology A phenotype in which a spore germinates to produce a cell that is septated and has abnormal morphology (i.e. size, shape, or structure), and that undergoes two or more rounds of cell division and then dies. FYPO_relaxed.owl FYPO:0002490 biolink:NamedThing inviable after spore germination, multiple cell divisions, swollen cell A phenotype in which a spore germinates to produce a cell that has a greater length, diameter, and volume than normal, and undergoes two or more rounds of cell division and then dies. The ratio between cell length and diameter remains normal. FYPO_relaxed.owl FYPO:0005319 biolink:NamedThing inviable after spore germination, multiple cell divisions, spherical cell with cell lysis A phenotype in which a spore germinates to produce a cell that is spherical, and undergoes two or more rounds of cell division before all cells die, and some cells lyse. FYPO_relaxed.owl FYPO:0005158 biolink:NamedThing decreased cell wall (1->6)-beta-D-glucan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of (1->6)-beta-D-glucan measured in the cell wall is lower than normal. FYPO_relaxed.owl FYPO:0002629 biolink:NamedThing galactose absent from cell wall A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactose measured in the cell wall is too low to detect. FYPO_relaxed.owl FYPO:0003133 biolink:NamedThing galactomannan absent from cell wall A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of galactomannan measured in the cell wall is too low to detect. FYPO_relaxed.owl FYPO:0003727 biolink:NamedThing galactose absent from cell wall glycoprotein glycan A phenotype in which the glycan moiety of a glycoprotein in the cell wall does not contain galactose residues. In wild-type cells, glycoprotein glycans contain mannose and galactose residues in a 1:1.2 ratio, and the galactose residues are connected by alpha-1,2 linkages. FYPO_relaxed.owl FYPO:0002409 biolink:NamedThing inviable after spore germination, single cell division, with elongated germ tube A phenotype in which a spore germinates to produce an elongated germ tube, and undergoes a single round of cell division. FYPO_relaxed.owl FYPO:0003015 biolink:NamedThing cell lysis during cellular response to salt stress An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost, during a cellular response to salt stress. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised. FYPO_relaxed.owl FYPO:0003016 biolink:NamedThing cell lysis during cellular response to non-ionic osmotic stress An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost, during a cellular response to non-ionic osmotic stress. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised. FYPO_relaxed.owl FYPO:0003440 biolink:NamedThing cell lysis during cytokinesis An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost, during cytokinesis. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised. FYPO_relaxed.owl FYPO:0007903 biolink:NamedThing cell lysis during mitotic interphase An inviable phenotype in which a cell lyses during mitotic interphase, i.e. the plasma membrane ruptures and cytoplasm is lost. Note that in fission yeast cell lysis, the integrity of the cell wall is also compromised. FYPO_relaxed.owl FYPO:0002297 biolink:NamedThing dispersed actin cortical patch localization during mitotic interphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches are localized throughout the cell cortex (rather than concentrated at the cell ends as in wild type cells) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0002304 biolink:NamedThing decreased RNA level during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to salt stress is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002305 biolink:NamedThing decreased RNA level during cellular response to non-ionic osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to non-ionic osmotic stress is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002307 biolink:NamedThing increased 5-phosphoribose 1-diphosphate binding A molecular function phenotype in which occurrence of 5-phosphoribose 1-diphosphate binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002309 biolink:NamedThing decreased IMP binding A molecular function phenotype in which occurrence of IMP binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002311 biolink:NamedThing decreased GMP binding A molecular function phenotype in which occurrence of GMP binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002331 biolink:NamedThing increased histone H3-K4 dimethylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 4 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0008052 biolink:NamedThing increased histone H3-K4 dimethylation during mitosis A cellular process phenotype observed in mitosis in which the dimethylation of lysine at position 4 of histone H3 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0002336 biolink:NamedThing normal chromatin silencing at silent mating-type cassette A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the silent mating-type cassettes is normal (i.e. indistinguishable from wild type). Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin. FYPO_relaxed.owl FYPO:0002360 biolink:NamedThing normal chromatin silencing at centromere A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromeric regions is normal (i.e. indistinguishable from wild type). Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core). FYPO_relaxed.owl FYPO:0003555 biolink:NamedThing normal chromatin silencing at subtelomere A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing in subtelomeric regions is normal (i.e. indistinguishable from wild type). Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin. FYPO_relaxed.owl FYPO:0004331 biolink:NamedThing normal chromatin silencing at centromere central core A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing is normal (i.e. indistinguishable from wild type) at the centromere central core. Chromatin silencing is the observed effect of processes that repress transcription at the centromere central core, which is normally assembled into CENP-A-containing chromatin. FYPO_relaxed.owl FYPO:0007226 biolink:NamedThing normal chromatin silencing at heterochromatin island A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at one or more heterochromatin islands is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008265 biolink:NamedThing normal chromatin silencing at rDNA A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing in at rDNA is normal (i.e. indistinguishable from wild type). Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin. FYPO_relaxed.owl FYPO:0002339 biolink:NamedThing decreased protein localization to nuclear periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is decreased. The nuclear periphery is the portion of the nuclear lumen proximal to the inner nuclear membrane. FYPO_relaxed.owl FYPO:0002530 biolink:NamedThing decreased protein localization to nucleoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is decreased. FYPO_relaxed.owl FYPO:0006642 biolink:NamedThing decreased protein localization to nucleus during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007073 biolink:NamedThing decreased protein localization to nuclear envelope during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear envelope is decreased. FYPO_relaxed.owl FYPO:0002568 biolink:NamedThing abolished protein localization to nuclear periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is abolished. FYPO_relaxed.owl FYPO:0005147 biolink:NamedThing abolished proteasome localization to nuclear periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a proteasome to the nuclear periphery is abolished. FYPO_relaxed.owl FYPO:0005148 biolink:NamedThing increased protein localization to nuclear periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is increased. The nuclear periphery is the portion of the nuclear lumen proximal to the inner nuclear membrane. FYPO_relaxed.owl FYPO:0005217 biolink:NamedThing increased proteasome localization to nuclear periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a proteasome to the nuclear periphery is increased. FYPO_relaxed.owl FYPO:0002346 biolink:NamedThing abnormal chromatin silencing at centromere outer repeat A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the outer repeat region of the centromere is abnormal. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin. FYPO_relaxed.owl FYPO:0002834 biolink:NamedThing decreased chromatin silencing at centromere A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromeric regions is decreased. FYPO_relaxed.owl FYPO:0005071 biolink:NamedThing increased chromatin silencing at centromere A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromeric regions is increased. FYPO_relaxed.owl FYPO:0007335 biolink:NamedThing abolished chromatin silencing at centromere inner repeat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing does not occur at centromere inner repeat regions. FYPO_relaxed.owl FYPO:0007319 biolink:NamedThing decreased stress granule assembly during glucose starvation A cellular process phenotype in which stress granule assembly occurs to a lower extent than normal when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0002349 biolink:NamedThing delayed onset of stress granule assembly during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly begins later than normal. FYPO_relaxed.owl FYPO:0007320 biolink:NamedThing increased stress granule assembly during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007321 biolink:NamedThing decreased stress granule assembly during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007322 biolink:NamedThing decreased stress granule assembly during cellular response to heat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly occurs to a lower extent than normal during a cellular response to heat. FYPO_relaxed.owl FYPO:0002352 biolink:NamedThing delayed onset of stress granule disassembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule disassembly begins later than normal. FYPO_relaxed.owl FYPO:0002356 biolink:NamedThing normal methylated histone residue binding A molecular function phenotype in which occurrence of binding by a gene product to a methylated histone residue in a protein is normal (i.e. indistinguishable from wild type). The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0003215 biolink:NamedThing normal protein-protein interaction during cellular response to hydrogen peroxide A molecular function phenotype in which the binding of one protein to another is normal (i.e. indistinguishable from wild type) during a cellular response to hydrogen peroxide. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0003432 biolink:NamedThing normal histone H3K9me binding A molecular function phenotype in which the binding of a protein to histone H3 methylated on the lysine at position 9 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005232 biolink:NamedThing normal protein complex binding A molecular function phenotype in which the binding of one protein to a protein complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the protein complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene. FYPO_relaxed.owl FYPO:0006305 biolink:NamedThing normal actin monomer binding A molecular function phenotype in which the binding of a protein to one or more actin monomers is normal (i.e. indistinguishable from wild type). The relevant actin-binding protein may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006725 biolink:NamedThing normal microtubule binding A molecular function phenotype in which occurrence of microtubule binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0008060 biolink:NamedThing normal mono ubiquitin binding A molecular function phenotype in which the binding of one protein to a ubiquitin monomer is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008271 biolink:NamedThing normal histone binding A molecular function phenotype in which the binding of a protein to a histone is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002358 biolink:NamedThing normal histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005865 biolink:NamedThing normal histone H3-K9 methylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 9 of histone H3 in silent mating-type cassettes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002359 biolink:NamedThing normal histone H3-K9 dimethylation at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in telomeric regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003232 biolink:NamedThing normal histone H3-K9 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003233 biolink:NamedThing normal histone H3-K9 methylation at heterochromatin island during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at heterochromatin islands is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003234 biolink:NamedThing normal histone H3-K9 methylation at heterochromatin domain during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 at heterochromatin domains is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005864 biolink:NamedThing normal histone H3-K9 methylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 9 of histone H3 in subtelomeric regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005866 biolink:NamedThing normal histone H3-K9 methylation at rDNA during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 9 of histone H3 at ribosomal DNA is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006989 biolink:NamedThing normal histone H3-K9 dimethylation at transposable element during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 is normal (i.e. indistinguishable from wild type) at transposable elements. FYPO_relaxed.owl FYPO:0008071 biolink:NamedThing normal spatial extent of histone H3-K9 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 occurs over the same portion of the chromosome as normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002365 biolink:NamedThing increased histone H4 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H4 acetylation occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005308 biolink:NamedThing increased histone H4-K8 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005309 biolink:NamedThing increased histone H4-K5 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 5 of histone H4 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007632 biolink:NamedThing increased histone H4-K16 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 16 of histone H4 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0008270 biolink:NamedThing increased H3-K56 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 56 of histone H3 occurs to a higher extent than normal. FYPO_relaxed.owl FYPO:0005532 biolink:NamedThing abnormal histone H4-K16 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 is abnormal. FYPO_relaxed.owl FYPO:0002367 biolink:NamedThing decreased histone H3-K4 dimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 4 of histone H3 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0002368 biolink:NamedThing decreased histone H3-K4 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 4 of histone H3 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0002369 biolink:NamedThing increased histone H3-K56 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 56 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0002374 biolink:NamedThing abnormal actin cortical patch morphology during mitosis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of actin cortical patches is abnormal during mitosis. FYPO_relaxed.owl FYPO:0005435 biolink:NamedThing inviable after spore germination with elongated germ tube and fragmented nucleus A phenotype in which a spore germinates to produce a cell that has an elongated germ tube and a nucleus that is broken into multiple small fragments, and does not go on to give rise to a viable cell population. FYPO_relaxed.owl FYPO:0002382 biolink:NamedThing increased histone H4 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H4 acetylation occurs to a greater extent than normal in centromere outer repeat regions. FYPO_relaxed.owl FYPO:0003415 biolink:NamedThing increased histone H4 acetylation at centromere central core during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H4 acetylation occurs to a greater extent than normal at the central core of centromeric regions. FYPO_relaxed.owl FYPO:0007306 biolink:NamedThing increased histone H4-K12 acetylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 12 of histone H4 in centromeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007315 biolink:NamedThing increased histone H4-K8 acetylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 in heterochromatin at subtelomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007631 biolink:NamedThing increased histone H4-K12 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 12 of histone H4 occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0002910 biolink:NamedThing decreased protein localization to chromatin at transcribed regions during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to transcribed regions of chromatin is decreased. FYPO_relaxed.owl FYPO:0004161 biolink:NamedThing decreased protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to regions of chromatin containing genes that can be transcribed by RNA polymerase II is decreased. FYPO_relaxed.owl FYPO:0004313 biolink:NamedThing decreased protein localization to CENP-A containing chromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to CENP-A containing chromatin is decreased. FYPO_relaxed.owl FYPO:0005167 biolink:NamedThing decreased protein localization to chromatin at centromere inner repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at centromere inner repeat regions is decreased. FYPO_relaxed.owl FYPO:0005386 biolink:NamedThing decreased protein localization to chromatin at chromosome arms A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin along chromosome arms is decreased. FYPO_relaxed.owl FYPO:0005555 biolink:NamedThing decreased mitotic cohesin loading A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin loading is decreased during the mitotic cell cycle. Cohesin loading is the topological linking of a cohesin ring complex to chromatin. FYPO_relaxed.owl FYPO:0006206 biolink:NamedThing decreased protein localization to chromatin during cellular response to phosphate starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is decreased during a cellular response to phosphate starvation. FYPO_relaxed.owl FYPO:0006729 biolink:NamedThing decreased protein localization to chromatin distal to replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to regions of chromatin distal to replication origins is decreased. FYPO_relaxed.owl FYPO:0006818 biolink:NamedThing decreased protein localization to chromatin at centromere outer repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at centromere outer repeat regions is decreased. FYPO_relaxed.owl FYPO:0007235 biolink:NamedThing decreased protein localization to chromatin at early replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at early replication origins (i.e. origins that normally fire early in S phase) is decreased. FYPO_relaxed.owl FYPO:0008249 biolink:NamedThing decreased protein localization to chromatin at protein coding gene A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more protein-coding genes is decreased. FYPO_relaxed.owl FYPO:0002386 biolink:NamedThing decreased protein localization to heterochromatin at centromere outer repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at centromere outer repeat regions is decreased. FYPO_relaxed.owl FYPO:0002387 biolink:NamedThing decreased protein localization to subtelomeric heterochromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at subtelomeres is decreased. FYPO_relaxed.owl FYPO:0002395 biolink:NamedThing decreased maintenance of protein localization to heterochromatin at centromere outer repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the maintenance of localization of a protein at a location in heterochromatin at centromere outer repeat regions is decreased. FYPO_relaxed.owl FYPO:0003573 biolink:NamedThing decreased protein localization to heterochromatin at silent mating-type cassette A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at the silenced mating-type cassettes is decreased. FYPO_relaxed.owl FYPO:0007654 biolink:NamedThing decreased protein localization to chromatin at heterochromatin island at meiotic gene during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the maintenance of localization of a protein at a location in heterochromatin at heterochromatin islands occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005918 biolink:NamedThing decreased protein localization to subtelomeric heterochromatin A cell phenotype the localization of a protein to heterochromatin in subtelomeric regions is decreased. FYPO_relaxed.owl FYPO:0004716 biolink:NamedThing decreased protein localization to subtelomeric heterochromatin during horsetail movement A cell phenotype in which the localization of a protein to heterochromatin at subtelomeres is decreased during the part of meiotic prophase I in which horsetail nuclear movement takes place. FYPO_relaxed.owl FYPO:0002389 biolink:NamedThing normal protein localization to heterochromatin at centromere outer repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at centromere outer repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008154 biolink:NamedThing normal protein localization to centromeric heterochromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric heterochromatin is normal (i.e. indistinguishable from wild type. FYPO_relaxed.owl FYPO:0005080 biolink:NamedThing normal protein localization to heterochromatin at centromere inner repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the centromere inner repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002391 biolink:NamedThing decreased protein localization to chromatin at rDNA A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at ribosomal DNA repeat regions is decreased. FYPO_relaxed.owl FYPO:0004081 biolink:NamedThing decreased protein localization to chromatin at tRNA genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at tRNA genes is decreased. FYPO_relaxed.owl FYPO:0005665 biolink:NamedThing abnormal actin cytoskeleton A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the actin cytoskeleton is abnormal. FYPO_relaxed.owl FYPO:0005666 biolink:NamedThing abnormal actin cytoskeleton during meiosis A physical cellular phenotype in which the amount, distribution, or morphology of all or part of the actin cytoskeleton is abnormal during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0007683 biolink:NamedThing wide actin fusion focus A physical cellular phenotype in which components of the actin fusion focus are more widely distributed along the shmoo tip than normal. FYPO_relaxed.owl FYPO:0002401 biolink:NamedThing microtubule bundles present in increased numbers A physical cellular phenotype in which cells contain more microtubule bundles than normal. FYPO_relaxed.owl FYPO:0002818 biolink:NamedThing microtubule bundles present in decreased numbers A physical cellular phenotype in which cells contain fewer microtubule bundles than normal. FYPO_relaxed.owl FYPO:0005559 biolink:NamedThing thick stable microtubule bundle A physical cellular phenotype in which stable microtubule bundles are thicker than normal. Stable microtubule bundles, also called Q-MT bundles, are found in quiescent cells. FYPO_relaxed.owl FYPO:0005560 biolink:NamedThing thin stable microtubule bundle A physical cellular phenotype in which stable microtubule bundles are thinner than normal. Stable microtubule bundles, also called Q-MT bundles, are found in quiescent cells. FYPO_relaxed.owl FYPO:0005561 biolink:NamedThing long stable microtubule bundle A physical cellular phenotype in which stable microtubule bundles are longer than normal. Stable microtubule bundles, also called Q-MT bundles, are found in quiescent cells. FYPO_relaxed.owl FYPO:0005565 biolink:NamedThing abnormal microtubule bundle during G0 to G1 transition A physical cellular phenotype in which the amount, distribution, or morphology of microtubule bundles is abnormal when the cell undergoes transition from G0 phase to G1. FYPO_relaxed.owl FYPO:0005686 biolink:NamedThing microtubule bundles present in decreased numbers during mitotic interphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer microtubule bundles than normal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005797 biolink:NamedThing short microtubule bundle A physical cellular phenotype in which microtubule bundles are shorter than normal. FYPO_relaxed.owl FYPO:0006195 biolink:NamedThing decreased number of elongated microtubule bundles curved around cell end A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which all detectable microtubules are present in fewer bundles than normal (usually only one or two), and bundles are longer than normal and curved around one or both ends of the cell. FYPO_relaxed.owl FYPO:0007979 biolink:NamedThing increased number of microtubules per bundle during mitotic interphase A physical cellular phenotype in which cells contain interphase microtubule bundles with more microtubules than normal. FYPO_relaxed.owl FYPO:0007980 biolink:NamedThing Increased microtubule overlap length in bundles during mitotic interphase: A physical cellular phenotype in which cells contain interphase microtubule bundles with microtubule overlaps longer than normal. FYPO_relaxed.owl FYPO:0007983 biolink:NamedThing microtubule bundles detached from the nuclear envelope A physical cellular phenotype observed during mitotic interphase in which some microtubule bundles are not anchored to the nuclear membrane. See PMID:15068790 FYPO_relaxed.owl FYPO:0003389 biolink:NamedThing viable elongated vegetative cell with swollen medial region A cell morphology phenotype in which a vegetative cell is viable, is elongated, has a larger diameter than normal near the equator (but not at the ends), and has an overall volume greater than normal. FYPO_relaxed.owl FYPO:0002424 biolink:NamedThing normal actin cortical patch localization during mitotic interphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch localization is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. Cortical patches are normally present at both old and new ends of the cell. FYPO_relaxed.owl FYPO:0003028 biolink:NamedThing normal actin cortical patch localization during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patch localization is normal during mitosis. FYPO_relaxed.owl FYPO:0002425 biolink:NamedThing abnormal actin cable organization during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cable organization is abnormal during mitosis. The process normally results in the assembly, arrangement of constituent parts, or disassembly of an actin cable. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts. FYPO_relaxed.owl FYPO:0002440 biolink:NamedThing abnormal actin cable distribution A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actin cable distribution is abnormal. The process normally establishes the spatial arrangement of actin cables within the cell. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts. FYPO_relaxed.owl FYPO:0003158 biolink:NamedThing abolished actin cable assembly A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin cables does not occur. FYPO_relaxed.owl FYPO:0005854 biolink:NamedThing increased actin cable assembly A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin cables is increased. FYPO_relaxed.owl FYPO:0002438 biolink:NamedThing short, misoriented actin cables A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin cables that are shorter than normal and abnormally oriented within the cell. FYPO_relaxed.owl FYPO:0002439 biolink:NamedThing short, thick, misoriented actin cables A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin cables that are shorter and thicker than normal, and abnormally oriented within the cell. FYPO_relaxed.owl FYPO:0006308 biolink:NamedThing thick actin cables in medial region A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form actin cables that are thicker than normal in the medial region of the cell. FYPO_relaxed.owl FYPO:0002441 biolink:NamedThing decreased rate of actin cable retrograde transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin cable retrograde transport is lower than normal. The process normally arrangement of actin cables from the periphery toward the interior of the cell. Actin cables are parallel actin filament bundles nucleated by formin, and are the most common form of actin filament bundles found in yeasts. FYPO_relaxed.owl FYPO:0002446 biolink:NamedThing decreased protein phosphorylation during cellular response to hydrogen peroxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0002457 biolink:NamedThing viable curved elongated vegetative cell with abnormal septum A cell morphology phenotype in which a vegetatively growing cell is viable, is elongated, is curved along the long axis, and contains one or more abnormal septa. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0002460 biolink:NamedThing viable branched, curved, elongated vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, branched, septated, elongated, and is curved along the long axis. FYPO_relaxed.owl FYPO:0004703 biolink:NamedThing viable curved, elongated, swollen vegetative cell A cell morphology phenotype in which a vegetatively growing cell is viable, is longer and has a larger volume than normal, and is curved along the long axis. In a curved cell, the long axis follows a smooth bend rather than a straight line. FYPO_relaxed.owl FYPO:0003500 biolink:NamedThing viable branched, elongated, multiseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, forms one or more branches near a septum, is elongated, and has more than one septum. FYPO_relaxed.owl FYPO:0003413 biolink:NamedThing inviable branched, elongated, multiseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, forms one or more branches near a septum, is elongated, and has more than one septum. FYPO_relaxed.owl FYPO:0002472 biolink:NamedThing abolished histone H2A phosphorylation during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of histone H2A does not occur during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0004262 biolink:NamedThing abolished protein phosphorylation during mitotic G2 phase during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during G2 phase of the mitotic cell cycle and during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0002603 biolink:NamedThing abolished histone H2A phosphorylation at mating type locus during mitotic S phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation does not occur at the mating type locus during S phase of the mitotic cell cycle. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be abolished. FYPO_relaxed.owl FYPO:0004260 biolink:NamedThing increased duration of protein localization to double-strand break site A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to the region of a chromosome at which a DNA double-strand break has occurred for longer than normal. FYPO_relaxed.owl FYPO:0005606 biolink:NamedThing delayed onset of protein localization to double-strand break site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the region of a chromosome at which a DNA double-strand break has occurred begins later than normal. FYPO_relaxed.owl FYPO:0005610 biolink:NamedThing decreased spatial extent of protein localization to double-strand break site A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein localizes to a smaller portion of the chromosome than normal in the region of a chromosome at which a DNA double-strand break has occurred. FYPO_relaxed.owl FYPO:0002484 biolink:NamedThing increased intergenic meiotic recombination A cellular process phenotype in which the occurrence of two meiotic reciprocal recombination events (crossovers) close to each other is incresed. As a result, the resolution of meiotic recombination intermediates results in the formation of a crossover at a higher frequency than normal, and the occurrence of intergenic meiotic recombination is increased. FYPO_relaxed.owl FYPO:0003791 biolink:NamedThing increased meiotic recombination at silent mating-type cassette A cellular process phenotype in which the occurrence of reciprocal meiotic recombination is increased at the silent mating-type cassettes. FYPO_relaxed.owl FYPO:0004057 biolink:NamedThing increased intragenic meiotic recombination A cellular process phenotype in which the occurrence of intragenic meiotic recombination is increased. Intragenic meiotic recombination can result in gene conversion events. FYPO_relaxed.owl FYPO:0002485 biolink:NamedThing decreased intergenic meiotic recombination A cellular process phenotype in which the occurrence of two meiotic reciprocal recombination events (crossovers) close to each other is decresed. As a result, the resolution of meiotic recombination intermediates results in the formation of a crossover at a lower frequency than normal, and the occurrence of intergenic meiotic recombination is decreased. FYPO_relaxed.owl FYPO:0003060 biolink:NamedThing decreased meiotic recombination at cis-acting homologous chromosome pairing region A cellular process phenotype in which the occurrence of reciprocal meiotic recombination at a cis-acting homologous chromosome pairing region such as the sme2 locus is decreased. FYPO_relaxed.owl FYPO:0003179 biolink:NamedThing decreased intragenic meiotic recombination A cellular process phenotype in which the occurrence of intragenic meiotic recombination is decreased. Intragenic meiotic recombination can result in gene conversion events. FYPO_relaxed.owl FYPO:0004058 biolink:NamedThing decreased meiotic recombination at CRE promoter A cellular process phenotype in which the occurrence of reciprocal meiotic recombination at a CRE promoter in a chromosome is decreased. FYPO_relaxed.owl FYPO:0004089 biolink:NamedThing decreased meiotic recombination during zygotic meiosis A cellular process phenotype in which the occurrence of meiotic recombination is decreased during a zygotic meiotic nuclear division. Zygotic meiosis takes place immediately after conjugation and karyogamy, without intervening vegetative growth and division of diploid cells. FYPO_relaxed.owl FYPO:0005375 biolink:NamedThing decreased sister chromatid meiotic recombination A cellular process phenotype in which the occurrence of meiotic recombination between alleles of one sister chromatid (intra-sister recombination) or between alleles on different sister chromatids (inter-sister recombination) is decreased. FYPO_relaxed.owl FYPO:0005433 biolink:NamedThing decreased meiotic recombination at hotspot A cellular process phenotype in which the occurrence of meiotic recombination at one or more recombination hotspots is decreased to the background level. The basal rate of recombination (i.e. away from hotspots) may remain normal or may be decreased. FYPO_relaxed.owl FYPO:0005434 biolink:NamedThing globally decreased meiotic recombination A cellular process phenotype in which the occurrence of meiotic recombination is decreased both at recombination hotspots and elsewhere in the genome. FYPO_relaxed.owl FYPO:0002492 biolink:NamedThing abolished DNA 5'-adenosine monophosphate hydrolase activity A molecular function phenotype in which DNA 5'-adenosine monophosphate hydrolase activity is absent. FYPO_relaxed.owl FYPO:0003071 biolink:NamedThing abolished single-stranded DNA 5'-3' exodeoxyribonuclease activity A molecular function phenotype in which a single-stranded DNA 5'-3' exodeoxyribonuclease activity is absent. FYPO_relaxed.owl FYPO:0002799 biolink:NamedThing normal protein degradation A cellular process phenotype in which protein degradation is normal (i.e. indistinguishable from wild type). Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0002501 biolink:NamedThing normal protein palmitoylation during meiosis A cellular process phenotype in which protein palmitoylation is normal (i.e. indistinguishable from wild type) during one or both meiotic nuclear divisions. Protein palmitoylation is the addition of a palmitoyl group to a protein amino acid. FYPO_relaxed.owl FYPO:0002514 biolink:NamedThing abnormal protein palmitoylation during meiosis A cellular process phenotype in which the palmitoylation of one or more specific proteins is abnormal during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0002511 biolink:NamedThing abolished protein palmitoylation during meiosis A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, does not occur during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0002508 biolink:NamedThing decreased protein palmitoylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the palmitoylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004836 biolink:NamedThing decreased protein oxidation during cellular response to hydrogen peroxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidation of one or more specific proteins, or of specific protein sites, is decreased during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0005679 biolink:NamedThing decreased protein deubiquitination following cellular response to hydroxyurea during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the deubiquitination of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal after cells have been exposed to hydroxyurea. FYPO_relaxed.owl FYPO:0005852 biolink:NamedThing decreased protein biotinylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the biotinylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006284 biolink:NamedThing decreased protein-proline dihydroxylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dihydroxylation of one or more proline residues in specific proteins, or at specific protein sites, occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0002512 biolink:NamedThing decreased protein palmitoylation during meiosis A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0002513 biolink:NamedThing increased protein palmitoylation during meiosis A cellular process phenotype in which the palmitoylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0006460 biolink:NamedThing increased histone H2A phosphorylation at protein coding gene during meiosis I A cellular process phenotype in which histone H2A phosphorylation occurs to a greater extent than normal in regions containing protein-coding genes during the first meiotic nuclear division. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0006461 biolink:NamedThing increased histone H2A phosphorylation at telomere during meiosis I A cellular process phenotype in which histone H2A phosphorylation occurs to a greater extent than normal in telomeric regions during the first meiotic nuclear division. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0006462 biolink:NamedThing increased histone H2A phosphorylation at silent mating-type cassette during meiosis I A cellular process phenotype in which histone H2A phosphorylation occurs to a greater extent than normal at the silent mating-type cassette during the first meiotic nuclear division. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0008047 biolink:NamedThing decreased histone H3-K4 dimethylation at centromere during meiosis A cellular process phenotype observed in meiosis in which dimethylation of lysine at position 4 of histone H3 is decreased at the centromere. FYPO_relaxed.owl FYPO:0008049 biolink:NamedThing increased histone H3-K4 dimethylation during meiosis A cellular process phenotype observed in meiosis in which dimethylation of lysine at position 4 of histone H3 is increased. FYPO_relaxed.owl FYPO:0008050 biolink:NamedThing abolished histone H3-K4 methylation during meiosis A cellular process phenotype observed in meiosis in which dimethylation of lysine at position 4 of histone H3 is abolished. FYPO_relaxed.owl FYPO:0004536 biolink:NamedThing abnormal response to mitotic cell cycle spindle assembly checkpoint signaling A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to mitotic cell cycle spindle assembly checkpoint signaling is abnormal (does not occur, or occurs abnormally). Abnormal arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal. FYPO_relaxed.owl FYPO:0004537 biolink:NamedThing mitotic spindle assembly checkpoint override A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to mitotic cell cycle spindle assembly checkpoint signaling does not occur. As a result, the septation initiation network (SIN) signaling pathway is activated despite activation of the mitotic spindle assembly checkpoint (SAC). Normally, under conditions that activate the SAC, SIN activation is inhibited and the cell cycle arrests in anaphase. In this phenotype, premature SIN activation leads to premature cytokinesis and the formation of cut cells. FYPO_relaxed.owl FYPO:0002520 biolink:NamedThing decreased frequency of conjugation with h+ cells A cell population phenotype in which a smaller than normal proportion of cells in the population undergoes conjugation with wild type h+ cells. FYPO_relaxed.owl FYPO:0002521 biolink:NamedThing decreased frequency of conjugation with h- cells A cell population phenotype in which a smaller than normal proportion of cells in the population undergoes conjugation with wild type h- cells. FYPO_relaxed.owl FYPO:0007699 biolink:NamedThing decreased frequency of conjugation with non-sister cells A cell population phenotype in which a smaller than normal proportion of cells in a homothallic population undergoes conjugation with non-sister cells. FYPO_relaxed.owl FYPO:0002531 biolink:NamedThing abolished protein localization to nucleoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abolished. FYPO_relaxed.owl FYPO:0002532 biolink:NamedThing delayed onset of protein localization to nucleoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm begins later than normal. FYPO_relaxed.owl FYPO:0002533 biolink:NamedThing abnormal protein localization to nucleoplasm during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abnormal during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0002537 biolink:NamedThing abnormal protein localization to nucleoplasm during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abnormal during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0002541 biolink:NamedThing increased protein localization to nucleoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is increased. FYPO_relaxed.owl FYPO:0003748 biolink:NamedThing abnormal protein localization to nuclear body A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to nuclear bodies is abnormal. FYPO_relaxed.owl FYPO:0003042 biolink:NamedThing abolished protein localization to nuclear exosome focus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to nuclear exosome foci does not occur. Nuclear exosome foci, also called Mmi1 nuclear foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle, such as Mmi1, Iss10, and Red1. FYPO_relaxed.owl FYPO:0003688 biolink:NamedThing abolished protein localization to nucleolus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus is abolished. FYPO_relaxed.owl FYPO:0003910 biolink:NamedThing abolished VLP localization to nucleus during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of retrotransposon nucleocapsid complexes (also called virus-like particles, VLPs) to the nucleus is abolished. FYPO_relaxed.owl FYPO:0004054 biolink:NamedThing abolished protein localization to nucleus during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished during a cellular response to salt stress. FYPO_relaxed.owl FYPO:0004188 biolink:NamedThing abolished protein localization to nucleus during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0004835 biolink:NamedThing abolished protein localization to nucleus during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0004886 biolink:NamedThing abolished protein localization to nuclear envelope during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear envelope is abolished. FYPO_relaxed.owl FYPO:0008206 biolink:NamedThing abolished protein localization to nucleus during hypoxia A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is abolished during hypoxic stress. FYPO_relaxed.owl FYPO:0002534 biolink:NamedThing abolished protein localization to nucleoplasm during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abolished during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0002538 biolink:NamedThing abolished protein localization to nucleoplasm during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abolished during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0006918 biolink:NamedThing abolished protein localization to nucleoplasm during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is abolished during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0002535 biolink:NamedThing decreased protein localization to nucleoplasm during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is decreased during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0002536 biolink:NamedThing delayed onset of protein localization to nucleoplasm during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm begins later than normal during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0002540 biolink:NamedThing decreased protein localization to nucleoplasm during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is decreased during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0007272 biolink:NamedThing decreased protein localization to nucleoplasm during cellular response to DNA damage A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm is decreased during a cellular response to a DNA damage stimulus. FYPO_relaxed.owl FYPO:0002539 biolink:NamedThing delayed onset of protein localization to nucleoplasm during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleoplasm begins later than normal during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0003226 biolink:NamedThing delayed onset of protein localization to mitotic spindle A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle begins later than normal. FYPO_relaxed.owl FYPO:0004356 biolink:NamedThing increased protein localization to nucleolus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus is increased. FYPO_relaxed.owl FYPO:0006246 biolink:NamedThing increased protein localization to nucleus during cellular response to osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased during a cellular response to osmotic stress. FYPO_relaxed.owl FYPO:0008205 biolink:NamedThing increased protein localization to nucleus during hypoxia A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is increased during hypoxic stress. FYPO_relaxed.owl FYPO:0004195 biolink:NamedThing normal protein localization to telomere during meiosis A cell phenotype in which the localization of a protein to the telomere of a chromosome is normal (i.e. indistinguishable from wild type) during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0007853 biolink:NamedThing normal protein localization to centromere A cell phenotype in which the localization of a protein to the centromere of a chromosome is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002556 biolink:NamedThing decreased protein localization to medial cortex, with protein distributed in cell cortex near non-growing end, during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is decreased, and the protein is instead detected distributed throughout the cell cortex of half of the cell nearer the non-growing end. There may be little or no protein detected at the medial cortex. FYPO_relaxed.owl FYPO:0006638 biolink:NamedThing decreased protein localization to medial cortex, with protein distributed in cell cortex, during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is decreased, and the protein is instead detected distributed throughout the cell cortex. There may be little or no protein detected at the medial cortex. FYPO_relaxed.owl FYPO:0002719 biolink:NamedThing decreased protein localization to septum A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell septum is decreased. FYPO_relaxed.owl FYPO:0005551 biolink:NamedThing decreased protein localization to cleavage furrow A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cleavage furrow is decreased. FYPO_relaxed.owl FYPO:0003414 biolink:NamedThing normal protein localization to septum A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell septum is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006007 biolink:NamedThing normal duration of protein localization to cell division site A cell phenotype observed in the vegetative growth phase of the life cycle in which the duration of localization of a protein to the site of cell division is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006008 biolink:NamedThing normal onset of protein localization to cell division site A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the site of cell division begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events. FYPO_relaxed.owl FYPO:0002562 biolink:NamedThing delayed onset of protein localization to actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring begins later than normal. FYPO_relaxed.owl FYPO:0003336 biolink:NamedThing increased duration of protein localization to actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the actomyosin contractile ring for a longer time than normal. FYPO_relaxed.owl FYPO:0005021 biolink:NamedThing decreased duration of protein localization to actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to the actomyosin contractile ring for a shorter time than normal. FYPO_relaxed.owl FYPO:0005022 biolink:NamedThing decreased rate of protein localization to actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, localization of a protein to the actomyosin contractile ring is decreased. FYPO_relaxed.owl FYPO:0005467 biolink:NamedThing decreased protein localization to actomyosin contractile ring during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is decreased during mitosis. FYPO_relaxed.owl FYPO:0006940 biolink:NamedThing asymmetric protein localization to actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is radially asymmetric. FYPO_relaxed.owl FYPO:0007899 biolink:NamedThing increased rate of protein localization to actomyosin contractile ring A cell phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, localization of a protein to the actomyosin contractile ring is increased. FYPO_relaxed.owl FYPO:0007832 biolink:NamedThing delayed onset of protein localization to medial cortical node A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes begins later than normal. FYPO_relaxed.owl FYPO:0002564 biolink:NamedThing increased mature tRNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature transfer RNA (tRNA) measured in a cell is higher than normal. Total tRNA or a specific tRNA may be affected. FYPO_relaxed.owl FYPO:0006749 biolink:NamedThing increased pre-tRNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more transfer RNA precursor(s) (pre-tRNA) measured in a cell is higher than normal. Total pre-tRNA or a specific pre-tRNA may be affected. FYPO_relaxed.owl FYPO:0008102 biolink:NamedThing increased tRNA level during cellular response to phosphate starvation A cell phenotype in which the amount of tRNA measured in a cell is increased from normal when the cell is in the vegetative growth phase of the life cycle during phosphate starvation. FYPO_relaxed.owl FYPO:0002581 biolink:NamedThing increased level of nuclear tRNA processing intermediates with 3' extensions A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any tRNA processing intermediates with 3' extensions measured in the nucleus is higher than normal. FYPO_relaxed.owl FYPO:0002590 biolink:NamedThing increased level of mitochondrial tRNA processing intermediates with 3' extensions A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any tRNA processing intermediates with 3' extensions measured in the mitochondria is higher than normal. FYPO_relaxed.owl FYPO:0002933 biolink:NamedThing increased mature snoRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature snoRNA measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003557 biolink:NamedThing increased antisense RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of antisense RNA measured in a cell is higher than normal. Antisense RNA is transcribed from the coding, rather than the template, strand of DNA. FYPO_relaxed.owl FYPO:0004206 biolink:NamedThing increased mature snRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature snRNA measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0004207 biolink:NamedThing increased siRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature siRNA measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0004573 biolink:NamedThing increased telomeric transcript level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of non-coding RNA transcribed from telomeric regions measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0005995 biolink:NamedThing increased lncRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature long non-coding RNA (lncRNA) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006467 biolink:NamedThing increased mature ncRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature non-coding RNA (ncRNA) measured in a cell is higher than normal. Total ncRNA or a specific ncRNA may be affected. FYPO_relaxed.owl FYPO:0008149 biolink:NamedThing increased non functional ncRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of non-functional non-coding RNA transcribed measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002917 biolink:NamedThing abolished histone H3-K4 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 4 of histone H3 does not occur. FYPO_relaxed.owl FYPO:0002919 biolink:NamedThing abolished histone H3-K36 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 36 of histone H3 does not occur. FYPO_relaxed.owl FYPO:0004217 biolink:NamedThing abolished histone H4-K20 dimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 20 of histone H4 does not occur. FYPO_relaxed.owl FYPO:0004218 biolink:NamedThing abolished histone H4-K20 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 20 of histone H4 does not occur. FYPO_relaxed.owl FYPO:0002567 biolink:NamedThing normal centromeric outer repeat transcript level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNAs transcribed from the centromere outer repeat region measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008178 biolink:NamedThing normal centromeric inner repeat transcript level A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed from the centromere inner repeat region are present at normal levels (i.e. indistinguishable from wild-type). FYPO_relaxed.owl FYPO:0002570 biolink:NamedThing increased cellular dATP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dATP measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0007430 biolink:NamedThing increased cellular dGTP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dGTP measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002571 biolink:NamedThing decreased cellular dGTP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dGTP measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006203 biolink:NamedThing decreased cellular dATP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dATP measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0002572 biolink:NamedThing decreased cellular dTTP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dTTP measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006698 biolink:NamedThing decreased cellular 5-phosphoribosyl diphosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 5-phosphoribosyl diphosphate measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0006700 biolink:NamedThing decreased cellular CDP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of CDP measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006701 biolink:NamedThing decreased cellular UMP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of UMP measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006703 biolink:NamedThing decreased cellular UDP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of UDP measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006712 biolink:NamedThing decreased cellular acetyl-CoA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of acetyl-CoA measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006967 biolink:NamedThing decreased cellular AICAR level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of AICAR measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0006968 biolink:NamedThing decreased cellular SAICAR level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of SAICAR measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0005042 biolink:NamedThing normal protein localization to kinetochore A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003592 biolink:NamedThing increased anaphase-promoting complex binding A molecular function phenotype in which the binding of one protein to the anaphase-promoting complex (APC) occurs to a greater extent than normal. The protein whose binding to the APC may be encoded by the mutated gene, or may be encoded by a different gene. FYPO_relaxed.owl FYPO:0003632 biolink:NamedThing abnormal ribonucleoprotein complex binding A molecular function phenotype in which the binding of one gene product (RNA or protein) to a ribonucleoprotein complex is abnormal. The gene product whose binding to the ribonucleoprotein complex is affected may be encoded by the mutated gene, or may be encoded by a different gene. FYPO_relaxed.owl FYPO:0005142 biolink:NamedThing decreased proteasome core complex binding A molecular function phenotype in which occurrence of proteasome core complex binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005144 biolink:NamedThing decreased proteasome regulatory particle binding A molecular function phenotype in which occurrence of proteasome regulatory particle binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006799 biolink:NamedThing abolished nuclear MIS12/MIND complex binding A molecular function phenotype in which nuclear MIS12/MIND complex binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007173 biolink:NamedThing decreased mitotic checkpoint complex binding A molecular function phenotype in which occurrence of mitotic checkpoint complex binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007885 biolink:NamedThing decreased Lsm2-8 complex binding A molecular function phenotype in which occurrence of Lms2-8 complex binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002579 biolink:NamedThing altered mature tRNA level during vegetative growth A cell phenotype in which the amount of mature transfer RNA (tRNA) measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total tRNA or a specific tRNA may be affected. FYPO_relaxed.owl FYPO:0005857 biolink:NamedThing altered antisense RNA level during vegetative growth A cell phenotype in which the amount of antisense RNA measured in a cell differs from normal when the cell is in the vegetative growth phase of the life cycle. Total antisense RNA or a specific antisense RNA may be affected. FYPO_relaxed.owl FYPO:0002582 biolink:NamedThing normal mature mitochondrial tRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature mitochondrial transfer RNA (tRNA) measured in a cell is normal (i.e. indistinguishable from wild type). Total tRNA or a specific tRNA may be measured. FYPO_relaxed.owl FYPO:0004960 biolink:NamedThing normal mitochondrial RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in the mitochondria is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA may be measured. FYPO_relaxed.owl FYPO:0002583 biolink:NamedThing decreased mature tRNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature transfer RNA (tRNA) measured in a cell is lower than normal. Total tRNA or a specific tRNA may be affected. FYPO_relaxed.owl FYPO:0002932 biolink:NamedThing decreased mature snoRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature snoRNA measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0004204 biolink:NamedThing decreased mature snRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature snRNA measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0004205 biolink:NamedThing decreased siRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature siRNA measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0004816 biolink:NamedThing decreased antisense RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of antisense RNA measured in a cell is lower than normal. Antisense RNA is transcribed from the coding, rather than the template, strand of DNA. FYPO_relaxed.owl FYPO:0007406 biolink:NamedThing decreased lncRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature long non-coding RNA (lncRNA) measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0002584 biolink:NamedThing decreased mature mitochondrial tRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature mitochondrial transfer RNA (tRNA) measured in a cell is lower than normal. Total tRNA or a specific tRNA may be affected. FYPO_relaxed.owl FYPO:0004958 biolink:NamedThing altered RNA level in mitochondrion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in the mitochondrion differs from normal. FYPO_relaxed.owl FYPO:0002593 biolink:NamedThing decreased histone phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone phosphorylation occurs to a lower extent than normal. All histone phosphorylation may be affected, or phosphorylation of specific sites on specific histones may be decreased. FYPO_relaxed.owl FYPO:0002594 biolink:NamedThing increased histone phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone phosphorylation occurs to a greater extent than normal. All histone phosphorylation may be affected, or phosphorylation of specific sites on specific histones may be increased. FYPO_relaxed.owl FYPO:0002596 biolink:NamedThing increased histone H2A phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0002598 biolink:NamedThing decreased histone H2A phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased. FYPO_relaxed.owl FYPO:0004080 biolink:NamedThing increased histone H3-S10 phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which phosphorylation of serine at position 10 of histone H3 is increased. FYPO_relaxed.owl FYPO:0004891 biolink:NamedThing increased duration of histone H2A phosphorylation during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation lasts for a longer time than normal during a cellular response to ionizing radiation. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may persist longer than normal. FYPO_relaxed.owl FYPO:0006598 biolink:NamedThing decreased histone H3-T3 phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which phosphorylation of threonine at position 3 of histone H3 is decreased. FYPO_relaxed.owl FYPO:0008183 biolink:NamedThing decreased histone H3-S10 phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H3-S10 phosphorylation is decreased. FYPO_relaxed.owl FYPO:0007881 biolink:NamedThing increased duration of histone H2A phosphorylation during cellular response to methyl methanesulfonate A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of histone H2A phosphorylation is longer than normal during a cellular response to methyl methanesulfonate. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be affected. FYPO_relaxed.owl FYPO:0002601 biolink:NamedThing normal histone H2A phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is normal. All histone H2A phosphorylation may be assayed, or phosphorylation of specific sites on histone H2A may be measured. FYPO_relaxed.owl FYPO:0004079 biolink:NamedThing normal histone H3-S10 phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which phosphorylation of serine at position 10 of histone H3 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002602 biolink:NamedThing decreased histone H2A phosphorylation during mitotic S phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal during S phase of the mitotic cell cycle. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased. FYPO_relaxed.owl FYPO:0002609 biolink:NamedThing decreased histone H2A phosphorylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal at centromeric outer repeat regions. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased. FYPO_relaxed.owl FYPO:0002611 biolink:NamedThing decreased histone H2A phosphorylation at subtelomeric heterochromatin during mitotic S phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal at subtelomeric regions during S phase of the mitotic cell cycle. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased. FYPO_relaxed.owl FYPO:0004867 biolink:NamedThing decreased histone H2A phosphorylation during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a lower extent than normal during a cellular response to ionizing radiation. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be decreased. FYPO_relaxed.owl FYPO:0002604 biolink:NamedThing increased histone H2A phosphorylation at rDNA during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal at ribosomal DNA. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0002607 biolink:NamedThing increased histone H2A phosphorylation at centromeric tDNA during mitotic S phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal at tRNA genes (tDNA) in centromeric regions during S phase of the mitotic cell cycle. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0002608 biolink:NamedThing increased histone H2A phosphorylation during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal during a cellular response to hydroxyurea. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0005769 biolink:NamedThing increased histone H2A phosphorylation at G4 motif during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal in regions containing G-quartet (G4) motifs. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0005770 biolink:NamedThing increased histone H2A phosphorylation at highly transcribed RNA polymerase II genes during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal in regions where RNA polymerase II actively transcribes genes. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0005771 biolink:NamedThing increased histone H2A phosphorylation at nucleosome-depleted regions during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal in regions where nucleosomes are depleted. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0005772 biolink:NamedThing increased histone H2A phosphorylation at tRNA genes during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal at tRNA genes. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0006872 biolink:NamedThing increased histone H2A phosphorylation during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal during a cellular response to ionizing radiation. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0002605 biolink:NamedThing increased histone H2A phosphorylation at rDNA during mitotic G2 phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal at ribosomal DNA during G2 phase of the mitotic cell cycle. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0002606 biolink:NamedThing increased histone H2A phosphorylation at rDNA during mitotic S phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation occurs to a greater extent than normal at ribosomal DNA during S phase of the mitotic cell cycle. All histone H2A phosphorylation may be affected, or phosphorylation of specific sites on histone H2A may be increased. FYPO_relaxed.owl FYPO:0002610 biolink:NamedThing normal histone H2A phosphorylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is normal at centromeric outer repeat regions. All histone H2A phosphorylation may be assayed, or phosphorylation of specific sites on histone H2A may be measured. FYPO_relaxed.owl FYPO:0002612 biolink:NamedThing normal histone H2A phosphorylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is normal at subtelomeric regions. All histone H2A phosphorylation may be assayed, or phosphorylation of specific sites on histone H2A may be measured. FYPO_relaxed.owl FYPO:0002613 biolink:NamedThing normal histone H2A phosphorylation at mating type locus during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is normal at the mating type locus. All histone H2A phosphorylation may be assayed, or phosphorylation of specific sites on histone H2A may be measured. FYPO_relaxed.owl FYPO:0005954 biolink:NamedThing normal histone H2A phosphorylation during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone H2A phosphorylation is normal during a cellular response to ionizing radiation. All histone H2A phosphorylation may be assayed, or phosphorylation of specific sites on histone H2A may be measured. FYPO_relaxed.owl FYPO:0004482 biolink:NamedThing abnormal vacuole fusion during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole fusion, the merging of two vacuole membranes to form a single vacuole, is abnormal. FYPO_relaxed.owl FYPO:0007576 biolink:NamedThing abnormal vacuole fission A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole fission, i.e. the division of one vacuole into two or more separate vacuoles, is abnormal. FYPO_relaxed.owl FYPO:0002615 biolink:NamedThing decreased protein localization to pre-autophagosomal structure A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the pre-autophagosomal structure is decreased. FYPO_relaxed.owl FYPO:0002616 biolink:NamedThing increased protein localization to pre-autophagosomal structure A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the pre-autophagosomal structure is increased. FYPO_relaxed.owl FYPO:0007494 biolink:NamedThing increased ascospore wall beta-glucan level A cell phenotype in which the amount of beta-D-glucan measured in the spore wall is higher than normal. FYPO_relaxed.owl FYPO:0002632 biolink:NamedThing decreased dTTP biosynthetic process A metabolism phenotype observed in the vegetative growth phase of the life cycle in which dTTP biosynthesis is decreased. FYPO_relaxed.owl FYPO:0002638 biolink:NamedThing increased activation of mitotic spindle assembly checkpoint A cell cycle checkpoint phenotype in which the mitotic spindle assembly checkpoint is activated more frequently than normal, typically under conditions that do not cause checkpoint activation in wild-type cells. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. FYPO_relaxed.owl FYPO:0005727 biolink:NamedThing decreased rate of deactivation of mitotic spindle assembly checkpoint A cell cycle checkpoint phenotype in which deactivation of the mitotic spindle assembly checkpoint occurs more slowly than normal. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. FYPO_relaxed.owl FYPO:0005780 biolink:NamedThing decreased response to mitotic spindle assembly checkpoint signaling A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the mitotic spindle assembly checkpoint is decreased. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0005781 biolink:NamedThing decreased duration of mitotic spindle assembly checkpoint A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by the mitotic spindle assembly checkpoint is lower than in wild type. FYPO_relaxed.owl FYPO:0007437 biolink:NamedThing constitutive activation of mitotic spindle assembly checkpoint A cell cycle checkpoint phenotype in which the mitotic spindle assembly checkpoint is activated continuously. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. FYPO_relaxed.owl FYPO:0007438 biolink:NamedThing premature activation of mitotic spindle assembly checkpoint A cell cycle checkpoint phenotype in which activation of the mitotic spindle assembly checkpoint begins earlier than normal. The mitotic spindle assembly checkpoint normally delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. FYPO_relaxed.owl FYPO:0002649 biolink:NamedThing elongated kinetochore during mitosis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the kinetochore is longer than normal during mitosis. FYPO_relaxed.owl FYPO:0002650 biolink:NamedThing split kinetochore during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the kinetochore is divided into two or more parts. FYPO_relaxed.owl FYPO:0002653 biolink:NamedThing decreased vacuolar import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of vacuolar import, i.e. the transport of substances into the vacuole, is decreased. FYPO_relaxed.owl FYPO:0002657 biolink:NamedThing normal occurrence of NETO A regulation phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) occurs to the same extent as in wild-type cells. FYPO_relaxed.owl FYPO:0002659 biolink:NamedThing increased cellular trehalose 6-phosphate level during heat shock A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose 6-phosphate measured in a cell is higher than normal when the cell is subject to heat shock. FYPO_relaxed.owl FYPO:0002661 biolink:NamedThing decreased cellular trehalose 6-phosphate level during heat shock A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose 6-phosphate measured in a cell is lower than normal when the cell is subject to heat shock. FYPO_relaxed.owl FYPO:0006184 biolink:NamedThing altered level of osmotic stress responsive gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more messenger RNAs that are normally expressed during a cellular response to osmotic stress measured in a cell differs from normal (i.e. is higher or lower than observed in wild-type cells during vegetative growth). FYPO_relaxed.owl FYPO:0002665 biolink:NamedThing abnormal peptide-serine-N-acetyltransferase activity A molecular function phenotype in which the observed rate of peptide-serine-N-acetyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0002669 biolink:NamedThing abnormal peptide-glutamate-N-acetyltransferase activity A molecular function phenotype in which the observed rate of peptide-glutamate-N-acetyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0002666 biolink:NamedThing abolished peptide-serine-N-acetyltransferase activity A molecular function phenotype in which peptide-serine-N-acetyltransferase activity is absent. FYPO_relaxed.owl FYPO:0002667 biolink:NamedThing decreased peptide-serine-N-acetyltransferase activity A molecular function phenotype in which the observed rate of peptide-serine-N-acetyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0002668 biolink:NamedThing normal peptide-serine-N-acetyltransferase activity A molecular function phenotype in which the observed rate of peptide-serine-N-acetyltransferase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002670 biolink:NamedThing increased peptide-glutamate-N-acetyltransferase activity A molecular function phenotype in which the observed rate of peptide-glutamate-N-acetyltransferase activity is increased. FYPO_relaxed.owl FYPO:0006345 biolink:NamedThing increased duration of protein phosphorylation during nitrogen starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is longer than normal the cell is subject to nitrogen starvation. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0006515 biolink:NamedThing normal telomere length A physical cellular phenotype in which telomere length is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006516 biolink:NamedThing normal telomere length during G0 A physical cellular phenotype in which telomere length is normal (i.e. indistinguishable from wild type) during G0 phase. FYPO_relaxed.owl FYPO:0002688 biolink:NamedThing mitotic spindle collapse without elongation during prophase A cell phenotype in which a short mitotic spindle assembles, but does not elongate. The spindle pole bodies fail to separate, and often become spatially closer together, suggesting that the spindle shrinks. FYPO_relaxed.owl FYPO:0006475 biolink:NamedThing mitotic spindle collapse A cell phenotype in which a short mitotic spindle assembles, and may begin elongation, but does not elongate normally or completely, and eventually collapses. Upon collapse the spindle may break or shrink. FYPO_relaxed.owl FYPO:0005722 biolink:NamedThing mitotic spindle collapse during anaphase B elongation A cell phenotype in which a mitotic spindle assembles and begins to elongate, but becomes curved during anaphase B and eventually collapses. The spindle pole bodies separate, but often become spatially closer together as the spindle elongates and curves. FYPO_relaxed.owl FYPO:0006172 biolink:NamedThing mitotic spindle collapse without elongation during anaphase B A cell phenotype in which a short mitotic spindle assembles and elongates during prophase, but does not elongate further during anaphase B and eventually collapses. FYPO_relaxed.owl FYPO:0006643 biolink:NamedThing mitotic spindle collapse without elongation during metaphase A cell phenotype in which a short mitotic spindle assembles and elongates during prophase, but does not elongate further and eventually collapses during metaphase. FYPO_relaxed.owl FYPO:0002710 biolink:NamedThing spindle pole body absent from cell after meiosis II A cell phenotype in which nuclei formed by the second meiotic nuclear division do not contain detectable spindle pole bodies. FYPO_relaxed.owl FYPO:0002717 biolink:NamedThing normal vacuole fusion during cellular hypotonic response A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole fusion is normal (i.e. indistinguishable from wild type) during a cellular response to a hypotonic environment. FYPO_relaxed.owl FYPO:0002720 biolink:NamedThing sensitive to beta-glucanase A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to one or more enzymes that degrades cell wall polysaccharides by hydrolyzing beta-glucan linkages. Cells stop growing (and may die) at a concentration of such enzymes that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002721 biolink:NamedThing resistance to alpha-glucanase An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration than normal of one or more enzymes that degrades cell wall polysaccharides by hydrolyzing alpha-glucan linkages. FYPO_relaxed.owl FYPO:0006194 biolink:NamedThing inviable after spore germination, single or double cell division, spherical cell with cell lysis A phenotype in which a spore germinates to produce a cell that is spherical, and undergoes one or two rounds of cell division before all cells die, and some cells lyse. FYPO_relaxed.owl FYPO:0002727 biolink:NamedThing decreased saccharopine dehydrogenase activity A molecular function phenotype in which the observed rate of saccharopine dehydrogenase activity is decreased. FYPO_relaxed.owl FYPO:0002728 biolink:NamedThing inviable swollen elongated cell with enlarged nucleus upon entry into stationary phase A cell morphology phenotype in which a vegetative cell is inviable, is swollen, is elongated, and in which the nucleus is larger than normal, when the cell is in a culture entering stationary phase. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0007327 biolink:NamedThing DNA content decreased during G0 A cell phenotype which the total amount of DNA in a cell is lower than normal when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0003834 biolink:NamedThing normal duration of meiotic interphase A cell cycle phenotype in the duration of meiotic interphase, which begins after cytokinesis and ends when meiotic prophase begins, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006371 biolink:NamedThing normal duration of meiotic prophase I A cellular process phenotype in which the duration of prophase of the first meiotic nuclear division is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008090 biolink:NamedThing normal onset of mitotic anaphase B A cellular process phenotype in which mitotic anaphase begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events. FYPO_relaxed.owl FYPO:0002742 biolink:NamedThing increased level of iron transport gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more iron transport RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Iron transport RNAs are transcribed from genes whose products are involved in iron transport. FYPO_relaxed.owl FYPO:0002744 biolink:NamedThing increased level of amino acid transport gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more amino acid transport RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Amino acid transport RNAs are transcribed from genes whose products are involved in amino acid transport. FYPO_relaxed.owl FYPO:0002989 biolink:NamedThing increased level of transmembrane transport gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more iron transport messenger RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Iron transport m RNAs are transcribed from genes whose products are involved in iron transport. FYPO_relaxed.owl FYPO:0005005 biolink:NamedThing increased level of hexose transport gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more hexose transport RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Hexose transport RNAs are transcribed from genes whose products are involved in transport of six-carbon sugars. FYPO_relaxed.owl FYPO:0005506 biolink:NamedThing increased level of mitochondrial transport gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more mitochondrial transport mRNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Mitochondrial transport mRNAs are transcribed from genes whose products are involved in transport to or from the mitochondrion. FYPO_relaxed.owl FYPO:0002751 biolink:NamedThing decreased sulfate import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of sulfate ions into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0002764 biolink:NamedThing abolished tRNA (guanine(9)-N(1))-methyltransferase activity A molecular function phenotype in which tRNA (guanine(9)-N(1))-methyltransferase activity is absent. FYPO_relaxed.owl FYPO:0002765 biolink:NamedThing decreased tRNA (guanine(9)-N(1))-methyltransferase activity A molecular function phenotype in which the observed rate of tRNA (guanine(9)-N(1))-methyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0007386 biolink:NamedThing decreased histone H2B-K119 ubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B occurs to a lower extent than normal. Lysine 119 corresponds to the conserved C-terminal lysine of H2B. FYPO_relaxed.owl FYPO:0007818 biolink:NamedThing decreased protein ubiquitination during nitrogen starvation A cellular process phenotype in which the occurrence of ubiquitination of one or more specific proteins, or of specific protein sites, is decreased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0007256 biolink:NamedThing premature protein localization to meiotic spindle pole body during prophase I A cell phenotype in which the localization of a protein to the meiotic spindle pole body is begins earlier than normal during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0002778 biolink:NamedThing decreased protein sumoylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of sumoylation of one or more specific proteins, or of specific protein sites, is decreased. FYPO_relaxed.owl FYPO:0002786 biolink:NamedThing decreased riboflavin binding A molecular function phenotype in which occurrence of riboflavin binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0002795 biolink:NamedThing large vacuoles present in decreased numbers during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer, but larger, vacuoles than normal. FYPO_relaxed.owl FYPO:0006265 biolink:NamedThing large vacuoles present following cellular hypotonic response A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which vacuoles are larger than normal after a cell has been subjected to hypotonic osmotic stress. Normally, vacuoles enlarge during hypotonic stress, and return to the original smaller size when the stress is relieved, either due to shrinking or fission. FYPO_relaxed.owl FYPO:0002801 biolink:NamedThing normal protein degradation during nitrogen starvation A cellular process phenotype in which protein degradation is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0005195 biolink:NamedThing normal protein degradation during mitotic S phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is normal (i.e. indistinguishable from wild type) during S phase of the mitotic cell cycle. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0005410 biolink:NamedThing normal protein degradation during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein degradation is normal (i.e. indistinguishable from wild type) during mitosis. Protein degradation, also known as protein catabolism, is any metabolic process that results in the destruction of the native, active configuration of a protein, with or without the hydrolysis of peptide bonds. FYPO_relaxed.owl FYPO:0002806 biolink:NamedThing sensitive to arsenate A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to arsenate ions. Cells stop growing (and may die) at a concentration of arsenate that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005488 biolink:NamedThing sensitive to arsenite A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to arsenite ions. Cells stop growing (and may die) at a concentration of arsenite that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006156 biolink:NamedThing sensitive to sodium arsenite A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to sodium arsenite (AsNaO2). Cells stop growing (and may die) at a concentration of sodium arsenite that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0002807 biolink:NamedThing normal growth on arsenate A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing arsenate ions. FYPO_relaxed.owl FYPO:0002810 biolink:NamedThing normal septation index in stationary phase A cell population phenotype in which the septation index is normal (i.e. indistinguishable from wild type) in a population in stationary phase. The septation index is the proportion of the population undergoing septation at any given time. FYPO_relaxed.owl FYPO:0002813 biolink:NamedThing decreased cellular glycerol level during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell during a cellular response to salt stress is lower than normal. FYPO_relaxed.owl FYPO:0005457 biolink:NamedThing decreased cellular glycerol level during cellular response to osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell during a cellular response to osmotic stress is lower than normal. FYPO_relaxed.owl FYPO:0005458 biolink:NamedThing decreased cellular glycerol level during cellular response to non-ionic osmotic stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glycerol measured in a cell during a cellular response to non-ionic osmotic stress is lower than normal. FYPO_relaxed.owl FYPO:0005173 biolink:NamedThing increased protein localization to cell surface A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is increased. The cell surface refers to the external part of the cell wall and/or plasma membrane. FYPO_relaxed.owl FYPO:0008258 biolink:NamedThing decreased protein localization to cell surface A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell surface is decreased. The cell surface refers to the external part of the cell wall and/or plasma membrane. FYPO_relaxed.owl FYPO:0002820 biolink:NamedThing abolished histone H3-K9 methylation at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in telomeric regions does not occur. FYPO_relaxed.owl FYPO:0003097 biolink:NamedThing abolished histone H3-K9 methylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in centromere outer repeat regions does not occur. FYPO_relaxed.owl FYPO:0006813 biolink:NamedThing abolished histone H3-K9 trimethylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions does not occur. FYPO_relaxed.owl FYPO:0007530 biolink:NamedThing abolished histone H3-K9 dimethylation at heterochromatin island at meiotic gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 does not occur at heterochromatin islands near genes that are normally expressed during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0007886 biolink:NamedThing abolished histone H3-K9 dimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 does not occur. FYPO_relaxed.owl FYPO:0008188 biolink:NamedThing abolished histone H3-K9 trimethylation at centromere central core during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 in the centromere central core is abolished. FYPO_relaxed.owl FYPO:0008212 biolink:NamedThing abolished histone H3-K9 methylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 9 of histone H3 in silent mating-type cassettes does not occur. FYPO_relaxed.owl FYPO:0002821 biolink:NamedThing decreased protein localization to mitotic spindle pole body during interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during interphase. FYPO_relaxed.owl FYPO:0002822 biolink:NamedThing decreased protein localization to mitotic spindle pole body during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during mitosis. FYPO_relaxed.owl FYPO:0002823 biolink:NamedThing abolished protein localization to mitotic spindle pole body during interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body does not occur during interphase. FYPO_relaxed.owl FYPO:0004649 biolink:NamedThing abolished protein localization to mitotic spindle pole body during metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body during metaphase does not occur. FYPO_relaxed.owl FYPO:0004023 biolink:NamedThing increased duration of protein localization to mitotic spindle A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the mitotic spindle for a longer time than normal. FYPO_relaxed.owl FYPO:0004383 biolink:NamedThing premature protein localization to mitotic spindle A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle begins earlier than normal. FYPO_relaxed.owl FYPO:0004883 biolink:NamedThing abnormal protein localization to mitotic spindle midzone A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone is abnormal. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. FYPO_relaxed.owl FYPO:0002827 biolink:NamedThing decreased chromatin silencing at silent mating-type cassette A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the silent mating-type cassettes is decreased. FYPO_relaxed.owl FYPO:0004376 biolink:NamedThing increased chromatin silencing at silent mating-type cassette A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the silent mating-type cassettes is increased. FYPO_relaxed.owl FYPO:0007336 biolink:NamedThing abolished chromatin silencing at silent mating-type cassette A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing does not occur at the silent mating-type cassettes. FYPO_relaxed.owl FYPO:0003216 biolink:NamedThing decreased chromatin silencing at rDNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at ribosomal DNA repeat regions is decreased. FYPO_relaxed.owl FYPO:0004604 biolink:NamedThing decreased chromatin silencing at subtelomere A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at subtelomeric regions is decreased. FYPO_relaxed.owl FYPO:0007212 biolink:NamedThing decreased chromatin silencing at heterochromatin island A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at heterochromatin islands is decreased. FYPO_relaxed.owl FYPO:0002828 biolink:NamedThing constitutive protein kinase activity A regulation phenotype in which the basal activity of a protein kinase is increased relative to normal. Basal protein kinase activity is the activity observed in the absence of a regulator. Abnormally elevated basal activity may or may not reach the levels observed in the normal activated state. FYPO_relaxed.owl FYPO:0002831 biolink:NamedThing delayed onset of protein phosphorylation during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, begins later than normal during mitosis. FYPO_relaxed.owl FYPO:0003737 biolink:NamedThing delayed onset of protein phosphorylation during mitotic G2 phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, begins later than normal during G2 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0003952 biolink:NamedThing delayed onset of protein phosphorylation during cellular response to oxidative stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, begins later than normal during a cellular response to oxidative stress. FYPO_relaxed.owl FYPO:0006659 biolink:NamedThing delayed onset of protein phosphorylation during mitotic G1/S transition A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, begins later than normal during the G1/S transition of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0002833 biolink:NamedThing decreased polyuridylation-dependent decapping of nuclear-transcribed mRNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of polyuridylation-dependent decapping of nuclear-transcribed mRNA is decreased. All RNA decapping may be decreased, or one or more specific RNA molecules may be selectively affected. FYPO_relaxed.owl FYPO:0002835 biolink:NamedThing centromeric outer repeat transcript-derived siRNA absent An RNA metabolism phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the centromere outer repeat region are absent. FYPO_relaxed.owl FYPO:0002836 biolink:NamedThing increased centromeric outer repeat transcript-derived siRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the centromere outer repeat region are present at greater levels than normal. FYPO_relaxed.owl FYPO:0005522 biolink:NamedThing increased forward centromeric outer repeat transcript level A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed in the forward direction from the centromere outer repeat region are present at greater levels than normal. FYPO_relaxed.owl FYPO:0005523 biolink:NamedThing increased reverse centromeric outer repeat transcript level A cell phenotype observed in the vegetative growth phase of the life cycle in which RNAs transcribed in the reverse direction from the centromere outer repeat region are present at greater levels than normal. FYPO_relaxed.owl FYPO:0007339 biolink:NamedThing increased cen-dg RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which of RNAs transcribed from dg repeats in the centromere outer repeat region are present at higher levels than normal. FYPO_relaxed.owl FYPO:0006078 biolink:NamedThing increased ribosomal RNA-derived siRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from ribosomal RNA are present at greater levels than normal. FYPO_relaxed.owl FYPO:0006109 biolink:NamedThing increased subtelomeric transcript-derived siRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from subtelomeric regions are present at greater levels than normal. FYPO_relaxed.owl FYPO:0006110 biolink:NamedThing increased silent mating-type cassette transcript-derived siRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the silent mating-type cassettes are present at greater levels than normal. FYPO_relaxed.owl FYPO:0002837 biolink:NamedThing normal centromeric outer repeat transcript-derived siRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small interfering RNA transcripts derived from the centromere outer repeat region measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007453 biolink:NamedThing decreased protein level in Arp2/3 complex A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the Arp2/3 protein complex is lower than normal. FYPO_relaxed.owl FYPO:0008120 biolink:NamedThing decreased protein level in SAGA complex A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the SAGA complex is lower than normal. FYPO_relaxed.owl FYPO:0008121 biolink:NamedThing decreased protein level in NuA4 complex A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a protein measured in the NuA4 complex is lower than normal. FYPO_relaxed.owl FYPO:0002858 biolink:NamedThing increased (1->3)-beta-D-glucan level at cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of (1->3)-beta-D-glucan measured at the cell tip is greater than normal. FYPO_relaxed.owl FYPO:0007949 biolink:NamedThing increased (1->3)-beta-D-glucan level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of (1->3)-beta-D-glucan measured is greater than normal. FYPO_relaxed.owl FYPO:0005755 biolink:NamedThing increased (1->3)-beta-D-glucan level in periplasmic space A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of (1->3)-beta-D-glucan measured in the periplasmic space is greater than normal. FYPO_relaxed.owl FYPO:0002863 biolink:NamedThing slow cell growth during recovery from nitrogen starvation A cellular process phenotype in which cells elongate more slowly than normal when the cells are returned to nitrogen-rich medium following nitrogen starvation. FYPO_relaxed.owl FYPO:0006821 biolink:NamedThing slow vegetative cell growth A cellular process phenotype in which cells elongate more slowly than normal in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0002870 biolink:NamedThing increased protein localization to non-growing cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a non-growing cell tip is increased. FYPO_relaxed.owl FYPO:0004977 biolink:NamedThing increased protein localization to new cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a new cell tip is increased. FYPO_relaxed.owl FYPO:0004978 biolink:NamedThing increased protein localization to new growing cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a new growing cell tip is increased. FYPO_relaxed.owl FYPO:0002871 biolink:NamedThing decreased protein localization to growing cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a growing cell tip is decreased. FYPO_relaxed.owl FYPO:0003208 biolink:NamedThing decreased protein localization to cell tip, with protein distributed in plasma membrane or cortex A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is decreased, and an increased amount of the protein is instead detected distributed throughout the plasma membrane and/or cell cortex. FYPO_relaxed.owl FYPO:0003771 biolink:NamedThing decreased protein localization to plasma membrane of cell tip during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane surrounding the cell tip is decreased. FYPO_relaxed.owl FYPO:0005643 biolink:NamedThing decreased protein localization to cell tip, with protein mislocalized to nucleus and spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is decreased, and an increased amount of the protein is instead detected in the nucleus and at the spindle pole body. FYPO_relaxed.owl FYPO:0005833 biolink:NamedThing decreased protein transport along microtubule to cell tip during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cell tip is decreased. Transport of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007571 biolink:NamedThing abnormal cortical endoplasmic reticulum organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cortical endoplasmic reticulum (ER) organization is abnormal. Cortical ER organization results in the assembly, arrangement of constituent parts, or disassembly of the part of the endoplasmic reticulum that consists of highly dynamic tubules that are juxtaposed to the plasma membrane. FYPO_relaxed.owl FYPO:0006354 biolink:NamedThing abnormal transcription during glucose starvation A cellular process phenotype in which transcription is abnormal when the cell is subject to glucose starvation. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0007420 biolink:NamedThing abnormal transcription at telomere A cellular process phenotype in which transcription occurs to a greater extent than normal in telomeric regions. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0006355 biolink:NamedThing delayed onset of transcription during glucose starvation A cellular process phenotype in which transcription begins later than normal when the cell is subject to glucose starvation. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002880 biolink:NamedThing decreased transcription during glucose starvation and oxidative stress A cellular process phenotype in which transcription occurs to a lower extent than normal when the cell is subject to glucose starvation and oxidative stress simultaneously. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002881 biolink:NamedThing increased transcription during glucose starvation and oxidative stress A cellular process phenotype in which transcription occurs to a greater extent than normal when the cell is subject to glucose starvation and oxidative stress simultaneously. All genes, or a specific subset of genes, may be affected. FYPO_relaxed.owl FYPO:0002890 biolink:NamedThing abnormal horsetail nucleus morphology A physical cellular phenotype in which the size, shape, or structure of the horsetail nucleus is abnormal. The horsetail nucleus forms during the rapid oscillatory movement at meiotic prophase I. FYPO_relaxed.owl FYPO:0005651 biolink:NamedThing abnormal nuclear morphology during meiosis I A physical cellular phenotype in which the size, shape, or structure of the nucleus is abnormal during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0002891 biolink:NamedThing normal chromatin organization during vegetative growth A cellular process phenotype in which any process of chromatin organization is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. FYPO_relaxed.owl FYPO:0006368 biolink:NamedThing normal spatial extent of centromeric heterochromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a normal (i.e. indistinguishable from wild type) portion of the centromeric region of the chromosome. FYPO_relaxed.owl FYPO:0006842 biolink:NamedThing normal spatial extent of CENP-A containing nucleosome assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosomes containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) are assembled over a normal (i.e. indistinguishable from wild type) portion of the centromeric region of the chromosome. CENP-A-containing nucleosomes are assembled into chromatin around centromeres, encompassing the central core and centromeric inner repeat regions. FYPO_relaxed.owl FYPO:0006991 biolink:NamedThing normal spatial extent of heterochromatin assembly at protein coding gene A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a normal (i.e. indistinguishable from wild type) portion of the chromosome in regions containing protein-coding genes. FYPO_relaxed.owl FYPO:0007941 biolink:NamedThing normal chromatin organization during meiotic cell cycle A cellular process phenotype in which any process of chromatin organization is normal (i.e. indistinguishable from wild type) during the meiotic cell cycle. Chromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. FYPO_relaxed.owl FYPO:0002892 biolink:NamedThing normal heterochromatin organization during vegetative growth A cellular process phenotype in which any process of heterochromatin organization is normal (i.e. indistinguishable from wild type) in the vegetative growth phase of the life cycle. Heterochromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin. FYPO_relaxed.owl FYPO:0005527 biolink:NamedThing normal subtelomeric chromatin knob formation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the formation of chromatin knobs in subtelomeric regions is normal (i.e. indistinguishable from wild type). Chromatin knobs are highly condensed chromatin bodies formed from subtelomeric heterochromatin (observed on chromosomes 1 and 2). FYPO_relaxed.owl FYPO:0005179 biolink:NamedThing abnormal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase A cellular response phenotype observed in the vegetative growth phase of the life cycle in which the regulation of the mitotic cell cycle in response to ultraviolet light (UV) exposure during mitotic G1 phase is abnormal. Normally, cell cycle progression is slowed or arrested transiently following exposure to UV. The most common abnormality is for the cell cycle to progress as in the absence of UV. FYPO_relaxed.owl FYPO:0002901 biolink:NamedThing normal protein localization to kinetochore during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005072 biolink:NamedThing normal protein localization to centromeric chromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is normal (i.e. indistinguishable from wild type. FYPO_relaxed.owl FYPO:0007234 biolink:NamedThing normal protein localization to centromere central core A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the central core of the centromeric region of a chromosome is normal (i.e. indistinguishable from wild type. FYPO_relaxed.owl FYPO:0004214 biolink:NamedThing normal protein localization to kinetochore during meiosis I A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006599 biolink:NamedThing decreased protein localization to centromeric chromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is decreased. FYPO_relaxed.owl FYPO:0003351 biolink:NamedThing increased duration of protein localization to kinetochore during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the kinetochore of a chromosome for a longer time than normal. FYPO_relaxed.owl FYPO:0007174 biolink:NamedThing abnormal protein localization to kinetochore during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is abnormal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0008164 biolink:NamedThing abnormal protein localization to kinetochore during mitotic M phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is abnormal during mitotic M-phase. FYPO_relaxed.owl FYPO:0007294 biolink:NamedThing pear-shaped vegetative cell with actin localized to rounded end A cell phenotype in which a vegetative cell is pear-shaped, and in which actin is localized only to the rounded end of the cell. FYPO_relaxed.owl FYPO:0002906 biolink:NamedThing increased antisense primary transcript splicing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of splicing of antisense RNA primary transcripts is increased. FYPO_relaxed.owl FYPO:0003237 biolink:NamedThing increased RNA splicing at cryptic splice sites A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of splicing of RNA primary transcripts at sites that are not normally frequently used (or not spliced at all) is increased. FYPO_relaxed.owl FYPO:0003470 biolink:NamedThing increased mRNA splicing, via spliceosome A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mRNA splicing via the spliceosome is increased. FYPO_relaxed.owl FYPO:0002907 biolink:NamedThing circularized chromosome during mitotic G1 phase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which telomeres have fused, forming circular chromosomes, during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004789 biolink:NamedThing circularized chromosome during mitotic G2 phase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which telomeres have fused, forming circular chromosomes, during G2 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005049 biolink:NamedThing decreased protein localization to chromatin at RNA polymerase II promoter during nitrogen starvation A cell phenotype in which the localization of a protein to chromatin at RNA polymerase II promoters is decreased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0005576 biolink:NamedThing decreased protein localization to chromatin during meiotic cell cycle A cell phenotype in which the localization of a protein to chromatin is decreased during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0004127 biolink:NamedThing decreased histone H3-K4 dimethylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 4 of histone H3 at protein-coding genes occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005062 biolink:NamedThing increased histone H3-K4 methylation at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 4 of histone H3 in telomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005063 biolink:NamedThing increased histone H3-K4 methylation at mating type locus during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the methylation of lysine at position 4 of histone H3 at the mating type locus occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006751 biolink:NamedThing increased histone H3-K4 trimethylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 4 of histone H3 in heterochromatin at subtelomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006263 biolink:NamedThing increased histone H3-K36 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 36 of histone H3 is increased. FYPO_relaxed.owl FYPO:0007348 biolink:NamedThing decreased histone H3-K36 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 36 of histone H3 is decreased. FYPO_relaxed.owl FYPO:0002920 biolink:NamedThing normal histone H3-K36 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 36 of histone H3 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004219 biolink:NamedThing normal histone H4-K20 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 20 of histone H4 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004220 biolink:NamedThing normal histone H4-K20 monomethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which monomethylation of lysine at position 20 of histone H4 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005311 biolink:NamedThing normal histone H3-K4 methylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which methylation of lysine at position 4 of histone H3 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002922 biolink:NamedThing abolished histone H2B-K119 ubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B does not occur. Lysine 119 corresponds to the conserved C-terminal lysine of H2B. FYPO_relaxed.owl FYPO:0005928 biolink:NamedThing abolished protein polyubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the polyubiquitination of one or more specific proteins, or of specific protein sites, does not occur. FYPO_relaxed.owl FYPO:0005607 biolink:NamedThing abnormal histone H2B-K119 ubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B is abnormal. Lysine 119 corresponds to the conserved C-terminal lysine of H2B. FYPO_relaxed.owl FYPO:0005609 biolink:NamedThing decreased spatial extent of histone H2B-K119 ubiquitination at double-strand break site during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B occurs over a smaller portion of the chromosome than normal in regions surrounding double-strand DNA breaks. Lysine 119 corresponds to the conserved C-terminal lysine of H2B. FYPO_relaxed.owl FYPO:0007894 biolink:NamedThing increased histone H2B-K119 ubiquitination at subtelomeric heterochromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B is increased at subtelomeric heterochromatin. Lysine 119 corresponds to the conserved C-terminal lysine of H2B. FYPO_relaxed.owl FYPO:0007895 biolink:NamedThing increased histone H2B-K119 ubiquitination at pericentromeric heterochromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B is increased at pericentromeric heterochromatin. Lysine 119 corresponds to the conserved C-terminal lysine of H2B. FYPO_relaxed.owl FYPO:0005927 biolink:NamedThing normal protein monoubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the monoubiquitination of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007552 biolink:NamedThing normal protein ubiquitination during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the ubiquitination of one or more specific proteins, or of specific protein sites, is normal (i.e. indistinguishable from wild type) during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0002926 biolink:NamedThing abolished poly(A) RNA binding A molecular function phenotype in which an interaction between a protein and polyadenylated RNA (poly(A)RNA) does not occur. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0002927 biolink:NamedThing decreased poly(A) RNA binding A molecular function phenotype in which an interaction between a protein and a polyadenylated RNA (poly(A)RNA) is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0004289 biolink:NamedThing decreased GU repeat RNA binding A molecular function phenotype in which an interaction between a protein and GU repeat regions in an RNA is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0005101 biolink:NamedThing decreased poly(U) RNA binding A molecular function phenotype in which an interaction between a protein and a polyuridylated RNA (poly(U)RNA) is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0006684 biolink:NamedThing decreased centromeric transcript binding A molecular function phenotype in which an interaction between a protein and RNAs transcribed from the centromeric region is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0008053 biolink:NamedThing decreased intron acceptor binding A molecular function phenotype in which an interaction between a protein and mRNA intron acceptor is decreased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0002930 biolink:NamedThing decreased poly(A) tail length A phenotype in which polyadenylated RNA molecules have poly(A) tails of that are shorter than normal. FYPO_relaxed.owl FYPO:0002931 biolink:NamedThing increased poly(A) tail length A phenotype in which polyadenylated RNA molecules have poly(A) tails of that are longer than normal. FYPO_relaxed.owl FYPO:0003700 biolink:NamedThing increased snoRNA primary transcript level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of snoRNA primary transcripts measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0002950 biolink:NamedThing increased N-acetyl-D-glucosaminate level during G0 A cell phenotype in which the amount of N-acetyl-D-glucosaminate measured in a cell is higher than normal when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0002951 biolink:NamedThing increased L-ergothioneine level during G0 A cell phenotype in which the amount of L-ergothioneine measured in a cell is higher than normal when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0002952 biolink:NamedThing increased S-methyl-L-ergothioneine level during G0 A cell phenotype in which the amount of S-methyl-L-ergothioneine measured in a cell is higher than normal when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0002953 biolink:NamedThing increased S-adenosyl-L-methionine level during G0 A cell phenotype in which the amount of S-adenosyl-L-methionine measured in a cell is higher than normal when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0002954 biolink:NamedThing increased S-adenosyl-3-thiopropylamine level during G0 A cell phenotype in which the amount of S-adenosyl-3-thiopropylamine measured in a cell is higher than normal when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0003872 biolink:NamedThing increased glutathione level during G0 A cell phenotype in which the amount of glutathione measured in a cell is higher than normal when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0003873 biolink:NamedThing increased reactive oxygen species level during G0 A cell phenotype in which the amount of reactive oxygen species (ROS) measured in a cell is higher than normal when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0002958 biolink:NamedThing abnormal protein localization to Mei2 nuclear dot A cell phenotype in which the localization of a protein to the Mei2 nuclear dot is abnormal. The Mei2 nuclear dot is a nuclear body that contains Mei2, other proteins, and meiRNA, and forms during meiotic prophase in a fixed position in the horsetail nucleus. FYPO_relaxed.owl FYPO:0005121 biolink:NamedThing decreased level of early meiotic gene mRNA during meiotic cell cycle A cell phenotype in which the amount of RNA transcribed from early meiotic genes measured in a cell is lower than normal during the meiotic cell cycle. Early meiotic genes are normally transcribed during pre-meiotic S phase and recombination. FYPO_relaxed.owl FYPO:0005122 biolink:NamedThing decreased level of middle meiotic gene mRNA during meiotic cell cycle A cell phenotype in which the amount of RNA transcribed from middle meiotic genes measured in a cell is lower than normal during the meiotic cell cycle. Middle meiotic genes are normally transcribed during meiotic nuclear division. FYPO_relaxed.owl FYPO:0005123 biolink:NamedThing decreased level of late meiotic gene mRNA during meiotic cell cycle A cell phenotype in which the amount of RNA transcribed from late meiotic genes measured in a cell is lower than normal during the meiotic cell cycle. Late meiotic genes are normally transcribed during spore maturation. FYPO_relaxed.owl FYPO:0006145 biolink:NamedThing decreased RNA level during cellular response to copper ion during meiotic cell cycle A cell phenotype in which the amount of RNA measured in a cell during a cellular response to copper ions is lower than normal during the meiotic cell cycle. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0006147 biolink:NamedThing decreased level of early meiotic gene mRNA during cellular response to copper ion starvation during meiotic cell cycle A cell phenotype in which the amount of RNA transcribed from early meiotic genes measured in a cell is lower than normal during a cellular response to copper ion starvation during the meiotic cell cycle. Early meiotic genes are normally transcribed during pre-meiotic S phase and recombination. FYPO_relaxed.owl FYPO:0006170 biolink:NamedThing decreased RNA level during cellular response to copper ion starvation during meiotic cell cycle A cell phenotype in which the amount of RNA measured in a cell during a cellular response to copper ion starvation is lower than normal during the meiotic cell cycle. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0002960 biolink:NamedThing increased level of DSR-containing meiotic gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during the meiotic cell cycle, and that contain determinant of selective removal (DSR) sequences, measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). FYPO_relaxed.owl FYPO:0005127 biolink:NamedThing increased level of late meiotic gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from late meiotic genes measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). Late meiotic genes are normally transcribed during spore maturation. FYPO_relaxed.owl FYPO:0005128 biolink:NamedThing increased level of middle meiotic gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from middle meiotic genes measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). Middle meiotic genes are normally transcribed during meiotic nuclear division. FYPO_relaxed.owl FYPO:0007684 biolink:NamedThing increased level of early meiotic gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA transcribed from early meiotic genes measured in a cell is higher than normal (i.e. higher than observed in wild-type cells during vegetative growth). Early meiotic genes are normally transcribed during pre-meiotic S phase and recombination. FYPO_relaxed.owl FYPO:0003043 biolink:NamedThing increased protein localization to Mei2 nuclear dot A cell phenotype in which the localization of a protein to the Mei2 nuclear dot is increased. FYPO_relaxed.owl FYPO:0002964 biolink:NamedThing increased protein localization to nuclear exosome focus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to nuclear exosome foci is increased. Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle, such as Mmi1, Iss10, and Red1. FYPO_relaxed.owl FYPO:0007280 biolink:NamedThing decreased protein localization to nuclear exosome focus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to nuclear exosome foci is decreased. Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle, such as Mmi1, Iss10, and Red1. FYPO_relaxed.owl FYPO:0002968 biolink:NamedThing normal protein localization to mitotic spindle pole body during G2 A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is normal (i.e. indistinguishable from wild type) during G2 phase of the cell cycle. FYPO_relaxed.owl FYPO:0003308 biolink:NamedThing normal protein localization to mitotic spindle pole body during interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is normal (i.e. indistinguishable from wild type) during interphase of the cell cycle. FYPO_relaxed.owl FYPO:0002971 biolink:NamedThing decreased protein localization to mitotic spindle pole body during telophase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during telophase. FYPO_relaxed.owl FYPO:0005211 biolink:NamedThing decreased protein localization to mitotic spindle pole body during anaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during anaphase. FYPO_relaxed.owl FYPO:0007992 biolink:NamedThing decreased protein localization to mitotic spindle pole body during metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during metaphase. FYPO_relaxed.owl FYPO:0002973 biolink:NamedThing increased ubiquitin ligase activity during mitotic metaphase A molecular function phenotype in which the observed rate of ubiquitin ligase activity is increased during metaphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0002976 biolink:NamedThing decreased protein localization to chromatin at MCB promoters during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is decreased during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0005314 biolink:NamedThing decreased protein localization to chromatin at MCB promoters during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is decreased. FYPO_relaxed.owl FYPO:0002977 biolink:NamedThing increased protein localization to chromatin at MCB promoters during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is increased during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0006740 biolink:NamedThing increased protein localization to chromatin at MCB promoters during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is increased. FYPO_relaxed.owl FYPO:0007551 biolink:NamedThing increased protein localization to chromatin during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0002978 biolink:NamedThing increased protein localization to chromatin during cellular response to methyl methanesulfonate A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased during a cellular response to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0002994 biolink:NamedThing increased protein localization to chromatin during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004066 biolink:NamedThing increased protein localization to chromatin at protein coding gene A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more protein-coding genes is increased. FYPO_relaxed.owl FYPO:0004380 biolink:NamedThing increased protein localization to pericentric heterochromatin during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin in pericentric regions is increased. FYPO_relaxed.owl FYPO:0004598 biolink:NamedThing increased protein localization to chromatin during mitotic G2 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased during G2 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004961 biolink:NamedThing increased protein localization to chromatin at replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins is increased. FYPO_relaxed.owl FYPO:0005026 biolink:NamedThing increased protein localization to chromatin at chromosome arms A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased along the chromosome arms. FYPO_relaxed.owl FYPO:0005048 biolink:NamedThing increased protein localization to chromatin at RNA polymerase II promoter during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at RNA polymerase II promoters is increased. FYPO_relaxed.owl FYPO:0005897 biolink:NamedThing increased protein localization to chromatin during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is increased during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006300 biolink:NamedThing increased protein localization to chromatin at centromere inner repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at centromere inner repeat regions is increased. FYPO_relaxed.owl FYPO:0006322 biolink:NamedThing increased protein localization to chromatin at stalled replication fork A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at stalled replication forks is increased. FYPO_relaxed.owl FYPO:0006481 biolink:NamedThing increased mitotic cohesin ssDNA (lagging strand) loading A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin ssDNA (lagging strand) loading is increased during the mitotic cell cycle. Cohesin ssDNA (lagging strand) loading is the topological linking of a cohesin ring complex to single-stranded DNA, i.e. the lagging strand, in chromatin. FYPO_relaxed.owl FYPO:0006682 biolink:NamedThing increased protein localization to chromatin at centromere outer repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at centromere outer repeat regions is increased. FYPO_relaxed.owl FYPO:0006843 biolink:NamedThing increased histone H3 localization to chromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of histone H3 to chromatin is increased. FYPO_relaxed.owl FYPO:0007011 biolink:NamedThing increased protein localization to chromatin at ncRNA genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at non-coding RNA genes is increased. FYPO_relaxed.owl FYPO:0007279 biolink:NamedThing increased protein localization to euchromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to euchromatin is increased. FYPO_relaxed.owl FYPO:0007295 biolink:NamedThing increased protein localization to CENP-A containing chromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to CENP-A containing chromatin is increased. FYPO_relaxed.owl FYPO:0007344 biolink:NamedThing increased protein localization to chromatin at the centromere central core during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the central core of the centromeric regions is increased. FYPO_relaxed.owl FYPO:0007506 biolink:NamedThing increased protein localization to chromatin at promoter A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more specific promoter elements is increased. FYPO_relaxed.owl FYPO:0002979 biolink:NamedThing normal protein localization to chromatin during cellular response to methyl methanesulfonate A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type) during a cellular response to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0003069 biolink:NamedThing normal protein localization to chromatin at replication forks during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication forks is normal (i.e. indistinguishable from wild type) during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0003576 biolink:NamedThing normal protein localization to subtelomeric heterochromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin in subtelomeric regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004378 biolink:NamedThing normal protein localization to heterochromatin at silent mating-type cassette A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at the silenced mating-type cassettes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004962 biolink:NamedThing normal protein localization to chromatin at replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at replication origins is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005079 biolink:NamedThing normal protein localization to chromatin at centromere central core A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the central core of the centromeric regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005082 biolink:NamedThing normal protein localization to chromatin at long terminal repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at long terminal repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005083 biolink:NamedThing normal protein localization to chromatin at ncRNA gene A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at non-coding RNA (ncRNA) genes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005236 biolink:NamedThing normal protein localization to chromatin at stalled replication fork A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at stalled replication forks is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005529 biolink:NamedThing normal protein localization to chromatin at boundary element IRC1L A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the IRC1L boundary element is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006033 biolink:NamedThing normal protein localization to chromatin during mitotic DNA replication A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type) during mitotic DNA replication. FYPO_relaxed.owl FYPO:0006732 biolink:NamedThing normal protein localization to chromatin distal to replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to transcribed regions of chromatin is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007278 biolink:NamedThing normal protein localization to euchromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to euchromatin is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007536 biolink:NamedThing normal protein localization to chromatin at RNA polymerase II-transcribed genes during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to regions of chromatin containing genes that can be transcribed by RNA polymerase II is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007619 biolink:NamedThing normal protein localization to chromatin during cellular response to oxidative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin is normal (i.e. indistinguishable from wild type) when the cell is subject to oxidative stress. FYPO_relaxed.owl FYPO:0007731 biolink:NamedThing normal protein localization to chromatin at 3' end of genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin at the 3' ends of genes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008245 biolink:NamedThing normal protein localization to chromatin at gene promoter region A cell phenotype in which the localization of a protein to chromatin at one or more specific promoter elements is normal (i.e. indistinguishable from wild type) during vegetative growth. FYPO_relaxed.owl FYPO:0008250 biolink:NamedThing normal protein localization to chromatin at protein coding gene A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at one or more protein-coding genes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0002981 biolink:NamedThing increased chromatin binding during cellular response to methyl methanesulfonate A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is increased during a cellular response to methyl methanesulfonate. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0002986 biolink:NamedThing increased chromatin binding during cellular response to ionizing radiation A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is increased during a cellular response to ionizing radiation. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0005292 biolink:NamedThing increased chromatin binding during cellular response to hydroxyurea A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is increased during a cellular response to hydroxyurea. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0006756 biolink:NamedThing increased chromatin binding at promoter element during glucose starvation A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more specific promoter element(s) is increased when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0007499 biolink:NamedThing increased chromatin binding at cohesin associated regions A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more cohesin-associated regions (CARs) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0008062 biolink:NamedThing increased chromatin binding at centromere central core A molecular function phenotype in which occurrence of chromatin binding to the chromatin central core by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0003258 biolink:NamedThing increased proline import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of proline into the cell occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0002997 biolink:NamedThing normal negative regulation of DNA replication during cellular response to methyl methanesulfonate A regulation phenotype in which regulation of DNA replication during the mitotic cell cycle is normal (i.e. indistinguishable from wild type) during a cellular response to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0004252 biolink:NamedThing normal regulation of DNA replication during replication fork arrest A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of DNA replication is normal (i.e. indistinguishable from wild type) when one or more replication forks arrest. FYPO_relaxed.owl FYPO:0002998 biolink:NamedThing abolished actomyosin contractile ring assembly, clumped medial cortical nodes A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the assembly and distribution of actin filaments and associated proteins does not occur, resulting in the failure to form an actomyosin contractile ring, and in which medial cortical nodes form irregular clumps instead of coalescing into the medial cortex ring. FYPO_relaxed.owl FYPO:0002999 biolink:NamedThing normal protein localization to medial cortical node A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006026 biolink:NamedThing abolished actin filament bundle assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin filament bundles does not occur. FYPO_relaxed.owl FYPO:0003005 biolink:NamedThing inviable after spore germination, without cell division, with swollen, branched, elongated germ tube A phenotype in which a spore germinates to produce an elongated germ tube that has a larger diameter and volume than normal and forms branches, and does not go on to form a viable dividing cell. FYPO_relaxed.owl FYPO:0003968 biolink:NamedThing inviable after spore germination, without cell division, with swollen elongated germ tube and bidirectional cell growth from spore body A phenotype in which a spore germinates to produce an elongated germ tube that has a larger diameter and volume than normal, then initiates growth from the opposite end of the spore body, and does not go on to form a viable dividing cell. The cell may undergo one or two rounds of nuclear division, but does not undergo cytokinesis. FYPO_relaxed.owl FYPO:0003012 biolink:NamedThing mitosis with unreplicated DNA A cellular process phenotype in which cells attempt to undergo mitosis before they have begun to replicate genomic DNA. FYPO_relaxed.owl FYPO:0003014 biolink:NamedThing decreased rate of actomyosin contractile ring disassembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actomyosin contractile ring disassembly is decreased. Contractile ring disassembly is the part of cytokinesis in which the actomyosin contractile ring is disaggregated into its constituent components. FYPO_relaxed.owl FYPO:0003122 biolink:NamedThing decreased protein autophosphorylation during cellular response to DNA damage A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of autophosphorylation of one or more specific proteins, or of specific protein sites, is decreased during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0003027 biolink:NamedThing normal poly(A)+ mRNA export from nucleus A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of polyadenylated mRNA from the nucleus is normal. FYPO_relaxed.owl FYPO:0004397 biolink:NamedThing normal protein export from nucleus during vegetative growth A transport phenotype observed in the vegetative growth phase of the life cycle in which the export of protein from the nucleus is normal (i.e. indistinguishable from wild type). Export of all proteins or a specific protein may be assayed. FYPO_relaxed.owl FYPO:0003029 biolink:NamedThing decreased mRNA splicing, via spliceosome A cellular process phenotype in which the occurrence of mRNA splicing via the spliceosome is decreased. FYPO_relaxed.owl FYPO:0003030 biolink:NamedThing decreased splicing of mRNA introns with low A/U content and polypyrimidine tracts distal to branch site A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mRNA splicing via the spliceosome is decreased, where introns have low A/U content and polypyrimidine tracts located approximately 17-19 nt distal to the branch site. FYPO_relaxed.owl FYPO:0003242 biolink:NamedThing decreased splicing of mRNA introns with low A/U content A cellular process phenotype in which the occurrence of mRNA splicing via the spliceosome is decreased, where introns have low A/U content. FYPO_relaxed.owl FYPO:0007515 biolink:NamedThing decreased RNA stability during cellular response to oxidative stress A cell phenotype in which RNA stability is decreased during a cellular response to oxidative stress. RNA molecules are more likely to degrade over a given time period than in wild type. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0003041 biolink:NamedThing decreased snRNA splicing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of splicing of small nuclear RNA (snRNA) primary transcripts is decreased. FYPO_relaxed.owl FYPO:0003243 biolink:NamedThing decreased splicing of long introns A cellular process phenotype observed in the vegetative growth the occurrence of splicing of introns longer than about 45 nucleotides is decreased. FYPO_relaxed.owl FYPO:0003260 biolink:NamedThing decreased RNA splicing at cryptic splice sites A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of splicing of RNA primary transcripts at sites that are not normally frequently used is decreased. FYPO_relaxed.owl FYPO:0003101 biolink:NamedThing decreased heterochromatin assembly at protein coding gene A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly occurs to a lower extent than normal in regions containing protein-coding genes. Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent. FYPO_relaxed.owl FYPO:0004544 biolink:NamedThing increased duration of heterochromatin maintenance A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of heterochromatin maintenance is longer than normal. Heterochromatin maintenance is the process that preserves heterochromatin in a stable functional or structural state. FYPO_relaxed.owl FYPO:0004809 biolink:NamedThing decreased duration of heterochromatin maintenance involved in chromatin silencing at centromere outer repeat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of heterochromatin maintenance is shorter than normal in the context of chromatin silencing at centromere outer repeat regions. FYPO_relaxed.owl FYPO:0005528 biolink:NamedThing decreased subtelomeric chromatin knob formation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the formation of chromatin knobs in subtelomeric regions is decreased. Chromatin knobs are highly condensed chromatin bodies formed from subtelomeric heterochromatin (observed on chromosomes 1 and 2). FYPO_relaxed.owl FYPO:0005922 biolink:NamedThing decreased heterochromatin assembly at subtelomere A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly occurs to a lower extent than normal in subtelomeric regions. Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent. FYPO_relaxed.owl FYPO:0006260 biolink:NamedThing abolished subtelomeric chromatin knob formation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the formation of chromatin knobs in subtelomeric regions does not occur. Chromatin knobs are highly condensed chromatin bodies formed from subtelomeric heterochromatin (observed on chromosomes 1 and 2). FYPO_relaxed.owl FYPO:0003045 biolink:NamedThing heterochromatin assembly beyond boundary element IRC1R A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger region near the centromere than normal, such that it extends beyond the IRC1R boundary element. FYPO_relaxed.owl FYPO:0004948 biolink:NamedThing increased spatial extent of centromeric heterochromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger portion of the centromeric region of the chromosome than normal. FYPO_relaxed.owl FYPO:0003046 biolink:NamedThing heterochromatin assembly beyond boundary element IRC3L A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger region near the centromere than normal, such that it extends beyond the IRC3L boundary element. FYPO_relaxed.owl FYPO:0005286 biolink:NamedThing heterochromatin assembly beyond boundary element IRC1L A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger region near the centromere than normal, such that it extends beyond the IRC1L boundary element. FYPO_relaxed.owl FYPO:0003047 biolink:NamedThing heterochromatin assembly beyond boundary element IRR A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger region near the silent mating-type cassette than normal, such that it extends beyond the IRR boundary element. FYPO_relaxed.owl FYPO:0004749 biolink:NamedThing increased spatial extent of subtelomeric heterochromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger portion of the subtelomeric region of the chromosome than normal. FYPO_relaxed.owl FYPO:0006985 biolink:NamedThing heterochromatin assembly beyond boundary element IRL A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger region near the silent mating-type cassette than normal, such that it extends beyond the IRL boundary element. FYPO_relaxed.owl FYPO:0006990 biolink:NamedThing increased spatial extent of heterochromatin assembly at protein coding gene A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a larger portion of the chromosome than normal in regions containing protein-coding genes. FYPO_relaxed.owl FYPO:0003049 biolink:NamedThing increased transcriptional readthrough A phenotype in which a transcript, i.e. an RNA molecule synthesized on a DNA template by RNA polymerase, is longer than normal due to transcription beyond the normal termination site. FYPO_relaxed.owl FYPO:0005219 biolink:NamedThing decreased transcript length A phenotype in which a transcript, i.e. an RNA molecule synthesized on a DNA template by RNA polymerase, is shorter than normal. FYPO_relaxed.owl FYPO:0003051 biolink:NamedThing normal homologous chromosome pairing at cis-acting homologous chromosome pairing region A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type) at a cis-acting homologous chromosome pairing region such as the omt3 locus on chromosome 1 or the sme2 locus on chromosome 2. FYPO_relaxed.owl FYPO:0003054 biolink:NamedThing decreased homologous chromosome pairing at cis-acting homologous chromosome pairing region A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased (i.e. occurs to a lower extent) at a cis-acting homologous chromosome pairing region such as the omt3 locus on chromosome 1 or the sme2 locus on chromosome 2. FYPO_relaxed.owl FYPO:0007945 biolink:NamedThing abnormal homologous chromosome pairing at cis-acting homologous chromosome pairing region during meiotic prophase I A cellular process phenotype in which homologous chromosome pairing during meiosis I prophase is abnormal at a cis-acting homologous chromosome pairing region such as the sme2 locus. FYPO_relaxed.owl FYPO:0003059 biolink:NamedThing normal RNA localization to chromatin A cell phenotype in which the localization of an RNA to chromatin is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005536 biolink:NamedThing normal RNA localization to nucleus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of an RNA to the nucleus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003067 biolink:NamedThing abnormal replication fork reversal A cell phenotype observed in the vegetative growth phase of the life cycle in which stalled replication forks are unwound four-stranded structures resembling Holliday junctions, but are not subsequently resolved correctly. FYPO_relaxed.owl FYPO:0003587 biolink:NamedThing loss of gross chromosomal rearrangement during replication fork processing A cell phenotype in which the increase in gross chromosomal rearrangements that normally results from processing arrested replication forks is diminished or abolished. FYPO_relaxed.owl FYPO:0003588 biolink:NamedThing increased gross chromosomal rearrangement during replication fork processing A cell phenotype in which the increase in gross chromosomal rearrangements that normally results from processing arrested replication forks is enhanced, i.e. the incidence of rearrangement increases more than in wild type when an arrested fork is processed. FYPO_relaxed.owl FYPO:0003589 biolink:NamedThing decreased replication slippage during replication fork processing A cell phenotype observed in the vegetative growth phase of the life cycle in which the increase in small deletions or duplications ("replication slippage") that normally results from processing arrested replication forks is diminished or abolished. FYPO_relaxed.owl FYPO:0004003 biolink:NamedThing delayed onset of replication fork processing A cell phenotype observed in the vegetative growth phase of the life cycle in which replication fork processing begins later than normal. Replication fork processing is process in which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired and replication is restarted. FYPO_relaxed.owl FYPO:0004251 biolink:NamedThing increased DNA resection during replication fork processing A cell phenotype observed in the vegetative growth phase of the life cycle in which the extent of DNA resection upstream of a stalled replication fork is greater than normal. DNA resection is the 5'-to-3' degradation of one strand of DNA, leaving a stretch of single-stranded DNA. FYPO_relaxed.owl FYPO:0006086 biolink:NamedThing increased mitotic sister chromatid bridge formation during replication fork processing A cell phenotype in which one or more bridges consisting of unresolved intertwined sister chromatids form following replication fork arrest, and persist until mitotic anaphase. Bridges contain dsDNA and RPA-bound ssDNA, and may break, resulting in unequal sister chromatid segregation. FYPO_relaxed.owl FYPO:0006087 biolink:NamedThing abolished DNA resection during replication fork processing A cell phenotype observed in the vegetative growth phase of the life cycle in which DNA resection does not occur upstream of a stalled replication fork. DNA resection is the 5'-to-3' degradation of one strand of DNA, leaving a stretch of single-stranded DNA. FYPO_relaxed.owl FYPO:0006318 biolink:NamedThing decreased DNA resection during replication fork processing A cell phenotype observed in the vegetative growth phase of the life cycle in which the extent of DNA resection upstream of a stalled replication fork is lower than normal. DNA resection is the 5'-to-3' degradation of one strand of DNA, leaving a stretch of single-stranded DNA. FYPO_relaxed.owl FYPO:0007255 biolink:NamedThing decreased replication fork processing A cell phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of replication fork processing is decreased. Replication fork processing is process in which a DNA replication fork that has stalled (due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes) is repaired and replication is restarted. FYPO_relaxed.owl FYPO:0007532 biolink:NamedThing decreased replication fork colocalization with nuclear pore complex A cellular process phenotype observed in the vegetative growth phase of the life cycle in which arrested replication forks do not colocalize with nuclear pore complexes (NPCs) longer than actively replicating forks. Normally, arrested replication forks relocate to NPCs as part of replication fork processing, and remain anchored at NPCs while recombination-dependent replication takes place. FYPO_relaxed.owl FYPO:0007537 biolink:NamedThing increased replication slippage during replication fork processing A cell phenotype observed in the vegetative growth phase of the life cycle in which the increase in small deletions or duplications ("replication slippage") that normally results from processing arrested replication forks is enhanced. FYPO_relaxed.owl FYPO:0005396 biolink:NamedThing abolished protein localization to subtelomeric heterochromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to subtelomeric heterochromatin is abolished. FYPO_relaxed.owl FYPO:0008153 biolink:NamedThing abolished protein localization to heterochromatin at silent mating-type cassette during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at the silent mating-type cassette is abolished. FYPO_relaxed.owl FYPO:0003078 biolink:NamedThing abolished protein autophosphorylation during cellular response to DNA damage A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the autophosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to DNA damage. Protein autophosphorylation is the phosphorylation by a protein of one or more of its own amino acid residues, or residues on an identical protein. FYPO_relaxed.owl FYPO:0003081 biolink:NamedThing decreased genetic imprinting at mating-type locus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which genetic imprinting at the mating-type locus occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0003083 biolink:NamedThing abnormal replication fork arrest at mating-type locus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the mating-type locus is abnormal. FYPO_relaxed.owl FYPO:0003922 biolink:NamedThing increased replication fork arrest at tRNA locus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at abnormal replication fork arrest at sites within the eukaryotic tRNA transcription unit occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006603 biolink:NamedThing decreased replication fork arrest at RTS1 barrier A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the RTS1 barrier (normally located in the mating-type region) occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006604 biolink:NamedThing decreased replication fork arrest at tRNA locus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at abnormal replication fork arrest at sites within the eukaryotic tRNA transcription unit occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007679 biolink:NamedThing increased replication fork arrest at RTS1 barrier A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the RTS1 barrier (normally located in the mating-type region) occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0003085 biolink:NamedThing decreased replication fork arrest at mating-type locus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the mating-type locus occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0003920 biolink:NamedThing increased replication fork arrest at mating-type locus A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the mating-type locus occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005360 biolink:NamedThing reversed RTS1 barrier polarity A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the RTS1 replication termination site prevents replication fork movement in the opposite of normal direction. Normally, RTS1 acts as a barrier to replication forks moving in the cenII-distal direction. FYPO_relaxed.owl FYPO:0003086 biolink:NamedThing normal chromatin binding A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003296 biolink:NamedThing normal ribosome binding A molecular function phenotype in which occurrence of ribosome binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005233 biolink:NamedThing normal MCM complex binding A molecular function phenotype in which the binding of one protein to an MCM complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the MCM complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene. FYPO_relaxed.owl FYPO:0006024 biolink:NamedThing normal actin filament binding A molecular function phenotype in which the binding of a protein to one or more actin filaments is normal (i.e. indistinguishable from wild type). The relevant actin-binding protein may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006561 biolink:NamedThing normal CDK-cyclin complex binding during mitotic G1 phase A molecular function phenotype in which the binding of one protein to a CDK-cyclin complex is normal (i.e. indistinguishable from wild type) during the G1 phase of the mitotic cell cycle. The protein whose binding to the CDK-cyclin complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene. FYPO_relaxed.owl FYPO:0006798 biolink:NamedThing normal nuclear MIS12/MIND complex binding A molecular function phenotype in which the binding of one protein to the nuclear MIS12/MIND complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene. FYPO_relaxed.owl FYPO:0007544 biolink:NamedThing normal cohesin complex binding A molecular function phenotype in which the binding of one protein to a cohesin complex is normal (i.e. indistinguishable from wild type). The protein whose binding to the cohesin complex is assayed may be encoded by the mutated gene, or may be encoded by a different gene. FYPO_relaxed.owl FYPO:0003087 biolink:NamedThing normal chromatin binding at mating-type region replication fork barrier A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type) at a replication fork barrier in the mating-type region. FYPO_relaxed.owl FYPO:0003799 biolink:NamedThing normal chromatin binding during recovery from nitrogen starvation A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type) in cells that are returned to nitrogen-rich medium following nitrogen starvation. FYPO_relaxed.owl FYPO:0003800 biolink:NamedThing normal chromatin binding at replication origin A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type) at an origin of replication. FYPO_relaxed.owl FYPO:0004879 biolink:NamedThing normal chromatin binding at centromere central core A molecular function phenotype in which the occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type) at the centromere central core. FYPO_relaxed.owl FYPO:0005930 biolink:NamedThing normal chromatin binding at centromere outer repeat A molecular function phenotype in which the occurrence of chromatin binding by a gene product (usually a protein) in a mutant is normal (i.e. indistinguishable from wild type) at the centromere outer repeat region. FYPO_relaxed.owl FYPO:0006757 biolink:NamedThing normal chromatin binding at promoter element during glucose starvation A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more specific promoter element(s) is normal (i.e. indistinguishable from wild type) when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0003090 biolink:NamedThing decreased replication fork arrest at rDNA repeats A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at abnormal replication fork arrest at sites within the eukaryotic rDNA repeat spacer occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0003921 biolink:NamedThing increased replication fork arrest at rDNA repeats A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at abnormal replication fork arrest at sites within the eukaryotic rDNA repeat spacer occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0003091 biolink:NamedThing decreased chromatin binding at rDNA replication fork barrier A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at a replication fork pausing site within the eukaryotic rDNA repeat spacer in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0003092 biolink:NamedThing decreased chromatin binding at mating-type region replication fork barrier A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at a replication fork pausing site within the mating-type region in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0003149 biolink:NamedThing decreased chromatin binding during cellular response to methyl methanesulfonate A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is decreased during a cellular response to methyl methanesulfonate. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0003801 biolink:NamedThing decreased chromatin binding at replication origin A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at an origin of replication is decreased. FYPO_relaxed.owl FYPO:0004227 biolink:NamedThing decreased nucleosome binding A molecular function phenotype in which occurrence of nucleosome binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0004876 biolink:NamedThing decreased chromatin binding at heat-shock-inducible genes during cellular response to heat shock A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) is decreased when the cell is subject to heat shock, at specific genes that are transcriptionally up-regulated during the heat shock. FYPO_relaxed.owl FYPO:0004877 biolink:NamedThing decreased chromatin binding at mitotically up-regulated genes A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) is decreased at specific genes that are transcriptionally up-regulated during mitosis. FYPO_relaxed.owl FYPO:0004907 biolink:NamedThing decreased chromatin binding at histone promoter A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) is decreased at the promoter regions of genes encoding histones. FYPO_relaxed.owl FYPO:0004984 biolink:NamedThing decreased chromatin binding at centromere central core A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at the central core of the centromeric regions is decreased. FYPO_relaxed.owl FYPO:0005050 biolink:NamedThing decreased chromatin binding during cellular response to nitrogen starvation A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is decreased when the cell is subject to nitrogen starvation. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0005341 biolink:NamedThing decreased chromatin binding during cellular response to hydroxyurea A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) in a mutant is decreased during a cellular response to hydroxyurea. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0005929 biolink:NamedThing decreased chromatin binding at centromere outer repeat A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at the centromere outer repeat region is decreased. FYPO_relaxed.owl FYPO:0006755 biolink:NamedThing decreased chromatin binding at promoter element during glucose starvation A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more specific promoter element(s) is decreased when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0007498 biolink:NamedThing decreased chromatin binding at cohesin associated regions A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more cohesin-associated regions (CARs) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene, and may normally bind DNA, protein, or both in chromatin. FYPO_relaxed.owl FYPO:0003095 biolink:NamedThing viable elongated vegetative cell, with progressive elongation A cell morphology phenotype in which a vegetative cell is viable and elongated, and continues to become longer over successive generations. The cell also undergoes mitosis beginning when the cell is longer than normal. FYPO_relaxed.owl FYPO:0003099 biolink:NamedThing normal heterochromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly is normal (i.e. indistinguishable from wild type). Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent. FYPO_relaxed.owl FYPO:0003100 biolink:NamedThing normal heterochromatin assembly at protein coding gene A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly is normal (i.e. indistinguishable from wild type) in regions containing protein-coding genes. Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent. FYPO_relaxed.owl FYPO:0003105 biolink:NamedThing increased transposable element-derived small RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from transposable element transcripts measured in a cell is greater than normal. FYPO_relaxed.owl FYPO:0004342 biolink:NamedThing increased LTR-derived RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any RNA transcribed from long terminal repeat elements (LTRs) measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0004343 biolink:NamedThing increased wtf-derived RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any RNA transcribed from wtf elements measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0003106 biolink:NamedThing stable shortened telomeres during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form telomeres that are shorter than normal, and that remain at a consistent length over successive generations. FYPO_relaxed.owl FYPO:0003107 biolink:NamedThing progressively shortening telomeres during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form telomeres that are shorter than normal, and that continue to decrease in length over successive generations. FYPO_relaxed.owl FYPO:0004656 biolink:NamedThing increased protein localization to telomere during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the telomere of a chromosome is increased. FYPO_relaxed.owl FYPO:0005104 biolink:NamedThing abnormal Lys63-specific deubiquitinase activity A molecular function phenotype in which the observed rate of Lys63-specific deubiquitinase activity is abnormal. FYPO_relaxed.owl FYPO:0005111 biolink:NamedThing abnormal ubiquitin-specific protease activity A molecular function phenotype in which the observed rate of ubiquitin-specific protease activity is abnormal. FYPO_relaxed.owl FYPO:0006409 biolink:NamedThing increased cellular nitric oxide level during stationary phase A cell phenotype in which the amount of nitric oxide measured in a cell is higher than normal when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0006410 biolink:NamedThing decreased cellular nitric oxide level during stationary phase A cell phenotype in which the amount of nitric oxide measured in a cell is lower than normal when the population in which the cell is found is in stationary phase. FYPO_relaxed.owl FYPO:0003121 biolink:NamedThing normal rate of homologous chromosome pairing at cis-acting homologous chromosome pairing region A cellular process phenotype in which the rate, or speed, of homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type) at a cis-acting homologous chromosome pairing region such as the sme2 locus. FYPO_relaxed.owl FYPO:0007352 biolink:NamedThing normal homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 1 A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type) at a cis-acting homologous chromosome pairing region on chromosome 1. FYPO_relaxed.owl FYPO:0007353 biolink:NamedThing normal homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 2 A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type) at a cis-acting homologous chromosome pairing region on chromosome 2. FYPO_relaxed.owl FYPO:0007354 biolink:NamedThing normal homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 3 A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is normal (i.e. indistinguishable from wild type) at a cis-acting homologous chromosome pairing region on chromosome 3. FYPO_relaxed.owl FYPO:0003123 biolink:NamedThing abolished protein localization to nuclear periphery during cellular response to heat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is abolished during a cellular response to heat. FYPO_relaxed.owl FYPO:0006230 biolink:NamedThing decreased cytoplasmic translational initiation during cellular response to oxidative stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translational initiation in the cytoplasm is decreased during a cellular response to oxidative stress. FYPO_relaxed.owl FYPO:0006231 biolink:NamedThing decreased cytoplasmic translational initiation during cellular response to osmotic stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translational initiation in the cytoplasm is decreased during a cellular response to osmotic stress. FYPO_relaxed.owl FYPO:0006520 biolink:NamedThing increased cytoplasmic translation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of cytoplasmic translation is increased. FYPO_relaxed.owl FYPO:0008130 biolink:NamedThing increased stop codon readthrough A metabolism phenotype observed in the vegetative growth phase of the life cycle in which translational readthough of a stop codon increases during cytoplasmic translation. FYPO_relaxed.owl FYPO:0003126 biolink:NamedThing post-anaphase array absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain a detectable post-anaphase array of microtubules. FYPO_relaxed.owl FYPO:0003303 biolink:NamedThing mislocalized post-anaphase array A cell phenotype observed in the vegetative growth phase of the life cycle in which the post-anaphase array of microtubules is present in an abnormal location. FYPO_relaxed.owl FYPO:0004922 biolink:NamedThing inviable elongated mononucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition A cell morphology phenotype in which a vegetative cell is inviable, contains one nucleus, has no septum, is elongated, and progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition. FYPO_relaxed.owl FYPO:0003129 biolink:NamedThing loss of punctate nuclear protein localization during cellular response to ionizing radiation A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that dots cannot be observed during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0003483 biolink:NamedThing decreased punctate nuclear protein localization during cellular response to ionizing radiation A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that fewer dots are observed than in normal (wild type) cells during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0005863 biolink:NamedThing loss of punctate nuclear protein localization A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that dots cannot be observed. FYPO_relaxed.owl FYPO:0004909 biolink:NamedThing loss of punctate nuclear protein localization, with protein distributed in nucleus A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that dots cannot be observed, and the protein is instead distributed throughout the nucleus. FYPO_relaxed.owl FYPO:0003134 biolink:NamedThing increased cell wall alpha-glucan level during cellular response to calcium starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of alpha-D-glucan measured in the cell wall is greater than normal during a cellular response to calcium starvation. FYPO_relaxed.owl FYPO:0003905 biolink:NamedThing normal meiotic spindle pole body morphology during meiosis II A physical cellular phenotype in which the size, shape, or structure of the spindle pole body is normal (i.e. indistinguishable from wild type) during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0007245 biolink:NamedThing normal meiotic spindle pole body A physical cellular phenotype in which the meiotic spindle pole bodies are normal (i.e. indistinguishable from wild type) with respect to structure, composition, location, and orientation. FYPO_relaxed.owl FYPO:0003155 biolink:NamedThing intermittent monopolar cell growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cells grow from one end, and do not grow continuously, but instead oscillate between periods of growth and pauses during which no growth occurs. FYPO_relaxed.owl FYPO:0004105 biolink:NamedThing abolished polar cell growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which polar cell growth does not occur. Cells grow without polarization, instead of growing only at the ends. FYPO_relaxed.owl FYPO:0003156 biolink:NamedThing normal monopolar cell growth A cellular process phenotype in which the monopolar growth of a cell is normal (i.e. indistinguishable from wild type in timing, extent, rate, etc.) in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0003157 biolink:NamedThing abnormal maintenance of protein location at growing cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to the growing cell tip, but then remains there for a longer or shorter time than normal. FYPO_relaxed.owl FYPO:0007450 biolink:NamedThing decreased maintenance of protein location in cell cortex of cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein is localized to one or both cell tip(s), but remains there for a shorter time than normal. FYPO_relaxed.owl FYPO:0003162 biolink:NamedThing RNA absent from cell during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect during a cellular response to salt stress. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003644 biolink:NamedThing RNA absent from cell during cellular response to thiamine starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect during a cellular response to thiamine starvation. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004070 biolink:NamedThing RNA absent from cell during cellular response to copper ion starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect during a cellular response to copper ion starvation. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004679 biolink:NamedThing polyadenylated 25S rRNA absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of polyadenylated 25S rRNA measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0006076 biolink:NamedThing siRNA absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature siRNA measured in a cell is too low to detect. FYPO_relaxed.owl FYPO:0007791 biolink:NamedThing RNA absent from cell during cellular response to magnesium starvation A cell phenotype in which the amount of RNA measured in a cell when the cell is subject to magnesium starvation is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0007794 biolink:NamedThing RNA absent from cell during cellular response to oxidative stress A cell phenotype in which the amount of RNA measured in a cell during a cellular response to oxidative stress is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0008156 biolink:NamedThing RNA absent from cell during cellular response to glucose starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect during a cellular response to glucose starvation. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003245 biolink:NamedThing telophase nuclear clustering A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the daughter nuclei formed by mitosis cluster in the middle of the cell during telophase. Normally, daughter nuclei move away from the cell division site during mitotic telophase. FYPO_relaxed.owl FYPO:0003302 biolink:NamedThing nucleus mislocalized towards cell tip during mitotic interphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleus is located near one cell tip (instead of at the midpoint of the long axis of the cell) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007966 biolink:NamedThing abolished nuclear displacement from cell division site after abolished mitotic sister chromatid separation A cell phenotype observed in the vegetative growth phase of the life cycle in which heterothallic haploid cells failing chromosome segregation and consequently nuclear division fail to displace the nucleus from the septation site. This is normally mediated by actin cables. FYPO_relaxed.owl FYPO:0009105 biolink:NamedThing mislocalized nucleus during mitotic telophase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the divided nuclei are mislocalized during telophase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0003175 biolink:NamedThing decreased nucleotide-excision repair during cellular response to UV A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleotide-excision repair is decreased during a cellular response to ultraviolet light. Nucleotide-excision repair is a DNA repair process in which a small region of the strand surrounding the damage is removed as an oligonucleotide, and the resulting small gap is filled in by the sequential action of DNA polymerase and DNA ligase. FYPO_relaxed.owl FYPO:0005137 biolink:NamedThing delayed onset of meiotic DNA double-strand break formation A cellular process phenotype in which generation of double-strand breaks at defined hotspots throughout the genome during meiosis I begins later than normal. FYPO_relaxed.owl FYPO:0007237 biolink:NamedThing increased meiotic DNA double-strand break formation near existing double-strand break A cellular process phenotype in which the frequency at which two double-strand breaks (DSBs) form close to each other during meiosis I is increased. FYPO_relaxed.owl FYPO:0004394 biolink:NamedThing lagging chromosomes during meiosis II A cellular process phenotype in which homologous chromosomes or sister chromatids do not move towards the spindle poles at the same time during meiosis II, but instead one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated. Segregation may stop before completing separation of chromosomes, or may eventually be completed. FYPO_relaxed.owl FYPO:0004570 biolink:NamedThing decreased meiotic sister chromatid separation A cellular process phenotype in which the occurrence of meiotic sister chromatid separation is decreased. FYPO_relaxed.owl FYPO:0008202 biolink:NamedThing equational sister chromatid separation at meiosis I A cellular process phenotype in which meiotic sister chromatid separation occurs in meiosis I due to erroneous merotelic kinetochore attachment. FYPO_relaxed.owl FYPO:0007524 biolink:NamedThing delayed onset of protein import into nucleus A transport phenotype observed in the vegetative growth phase of the life cycle in which the import of protein into the nucleus begins later than normal. Import of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003190 biolink:NamedThing decreased rate of cytoplasmic microtubule depolymerization during vegetative growth A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubule depolymerization, i.e. the removal of tubulin dimers from a cytoplasmic microtubule during interphase of the mitotic cell cycle, occurs at a lower rate, or speed, than normal. FYPO_relaxed.owl FYPO:0004975 biolink:NamedThing decreased rate of microtubule depolymerization behind moving spindle pole body A cellular process phenotype observed in the vegetative growth phase of the life cycle in which depolymerization (i.e. removal of tubulin dimers) of microtubules extending behind a moving spindle pole body occurs at a lower rate, or speed, than normal. FYPO_relaxed.owl FYPO:0003200 biolink:NamedThing normal transcription regulatory region sequence-specific DNA binding during cellular response to phosphate starvation A molecular function phenotype in which occurrence of DNA binding at a transcription regulatory region by a gene product is normal (i.e. indistinguishable from wild type) during a cellular response to phosphate starvation. The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005091 biolink:NamedThing normal DNA binding at PCB A molecular function phenotype in which occurrence of DNA binding at a pombe cell cycle box (PCB) by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007564 biolink:NamedThing normal DNA binding at MCB A molecular function phenotype in which occurrence of DNA binding at a Mlu1 cell cycle box (MCB) by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003201 biolink:NamedThing decreased rate of primary cell septum biogenesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of primary cell septum biogenesis is decreased. FYPO_relaxed.owl FYPO:0006831 biolink:NamedThing delayed onset of primary cell septum biogenesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum biogenesis begins later than normal. FYPO_relaxed.owl FYPO:0006832 biolink:NamedThing premature primary cell septum biogenesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which primary cell septum biogenesis begins earlier than normal. FYPO_relaxed.owl FYPO:0006834 biolink:NamedThing increased rate of primary cell septum biogenesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of primary cell septum biogenesis is increased. FYPO_relaxed.owl FYPO:0003205 biolink:NamedThing decreased primary cell septum thickness A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a primary septum that is thinner than normal. FYPO_relaxed.owl FYPO:0004651 biolink:NamedThing decreased secondary cell septum thickness A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a secondary septum that is thinner than normal. FYPO_relaxed.owl FYPO:0006079 biolink:NamedThing increased chromatin silencing at rDNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at ribosomal DNA repeat regions is increased. FYPO_relaxed.owl FYPO:0003217 biolink:NamedThing decreased chromatin silencing at centromere central core A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the chromatin silencing at the central core of the centromeric regions is decreased. FYPO_relaxed.owl FYPO:0005315 biolink:NamedThing increased chromatin silencing at centromere central core A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of negative regulation of transcription at the central core of the centromeric regions is increased. FYPO_relaxed.owl FYPO:0003223 biolink:NamedThing normal histone H3-K9 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003224 biolink:NamedThing normal histone H3-K14 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007221 biolink:NamedThing normal histone H3-K18 acetylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 18 of histone H3 in regions containing protein-coding genes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008160 biolink:NamedThing normal histone H3-K56 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 56 of histone H3 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008161 biolink:NamedThing normal histone H4-K16 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003244 biolink:NamedThing decreased mRNA splicing, via spliceosome, intron-specific A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mRNA splicing via the spliceosome takes place normally for some, but is decreased for other, specific introns. FYPO_relaxed.owl FYPO:0007199 biolink:NamedThing decreased splicing of mRNA introns with nonconsensus cis-splicing sequences A cellular process phenotype in which the occurrence of mRNA splicing via the spliceosome of introns that have one or more deviations from optimal cis-splicing sequences is decreased. Nonconsensus features may include a longer distance between the branch point and 3' splice site, lacking a polypyrimidine tract, or use of alternative 5' splice sites. FYPO_relaxed.owl FYPO:0008113 biolink:NamedThing increased intron retention A cellular process phenotype in which introns are retained at some, but not all introns at a higher level with increased frequency. Weak donor sequences are more affected. FYPO_relaxed.owl FYPO:0008118 biolink:NamedThing decreased splicing of introns with branch point-distant 3’-splice site A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mRNA splicing via the spliceosome is decreased for specific introns with longer than average (>21 bp) branch site to acceptor distance. FYPO_relaxed.owl FYPO:0008147 biolink:NamedThing decreased mRNA splicing, meiotic genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mRNA splicing of meiosis specific genes is decreased during meiosis. FYPO_relaxed.owl FYPO:0003247 biolink:NamedThing abolished histone H3 binding A molecular function phenotype in which occurrence of histone H3 binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0004231 biolink:NamedThing abnormal methylated histone binding A molecular function phenotype in which occurrence of methylated histone binding by a gene product (usually a protein) in a mutant is abnormal. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007158 biolink:NamedThing decreased histone H3 binding A molecular function phenotype in which occurrence of histone H3 binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007159 biolink:NamedThing decreased histone H4 binding A molecular function phenotype in which occurrence of histone H4 binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007835 biolink:NamedThing increased histone binding A molecular function phenotype in which histone binding by a gene product (usually a protein) in a mutant occurs to a greater extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0008187 biolink:NamedThing abolished histone H4 binding A molecular function phenotype in which occurrence of histone H4 binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003249 biolink:NamedThing decreased level of histone H3 at dh repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H3 measured at centromeric dh repeat regions is lower than normal. FYPO_relaxed.owl FYPO:0003251 biolink:NamedThing decreased transcription from SRE promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more sterol regulatory elements (SREs) occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004452 biolink:NamedThing decreased transcription from CDRE promoter in response to calcium ion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a calcineurin-dependent response element (CDRE)-containing promoter is decreased following a calcium ion stimulus. FYPO_relaxed.owl FYPO:0004479 biolink:NamedThing decreased transcription from CDRE promoter in response to salt stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a calcineurin-dependent response element (CDRE)-containing promoter is decreased during a cellular response to salt stress. FYPO_relaxed.owl FYPO:0004480 biolink:NamedThing decreased transcription from CDRE promoter in response to micafungin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a calcineurin-dependent response element (CDRE)-containing promoter is decreased during a cellular response to micafungin. FYPO_relaxed.owl FYPO:0005318 biolink:NamedThing decreased transcription from MCB promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more MluI cell cycle box factor elements (MCBs) occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005496 biolink:NamedThing decreased transcription from CRE promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006443 biolink:NamedThing decreased transcription of amino acid biosynthesis genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription of amino acid biosynthesis genes from RNA polymerase II promoters occurs to a lower extent than normal. Amino acid biosynthesis genes are those whose products are involved in amino acid biosynthetic processes. FYPO_relaxed.owl FYPO:0003254 biolink:NamedThing abolished arginine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of arginine into the cell is abolished. FYPO_relaxed.owl FYPO:0003255 biolink:NamedThing abolished proline import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of proline into the cell is abolished. FYPO_relaxed.owl FYPO:0003284 biolink:NamedThing decreased copper import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of copper ions into a cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006302 biolink:NamedThing abolished intra-arm chromosome contact change during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which changes in contacts within a chromosome arm that normally take place during mitosis do not occur. FYPO_relaxed.owl FYPO:0007566 biolink:NamedThing premature mitotic chromosome condensation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation begins earlier than normal. FYPO_relaxed.owl FYPO:0003291 biolink:NamedThing galactose absent from glycoprotein glycan A phenotype in which the glycan moiety of a glycoprotein does not contain galactose residues. In wild-type cells, glycoprotein glycans contain mannose and galactose residues in a 1:1.2 ratio, and the galactose residues are connected by alpha-1,2 linkages. FYPO_relaxed.owl FYPO:0003354 biolink:NamedThing decreased galactose level in glycoprotein glycan A phenotype in which the glycan moiety of a glycoprotein contains a lower amount of galactose residues than normal. In wild-type cells, glycoprotein glycans contain mannose and galactose residues in a 1:1.2 ratio, and the galactose residues are connected by alpha-1,2 linkages. FYPO_relaxed.owl FYPO:0004941 biolink:NamedThing decreased mannose level in glycoprotein glycan A phenotype in which the glycan moiety of a glycoprotein contains a lower amount of mannose residues than normal. In wild-type cells, glycoprotein glycans contain mannose and galactose residues in a 1:1.2 ratio. FYPO_relaxed.owl FYPO:0006273 biolink:NamedThing abnormal glycoprotein glycan structure in endoplasmic reticulum lumen A phenotype in which the structure of the glycan moiety of a nascent glycoprotein in the endoplasmic reticulum lumen differs from wild type. FYPO_relaxed.owl FYPO:0006277 biolink:NamedThing abnormal N-linked glycoprotein glycan structure A phenotype in which the structure of an N-linked glycan moiety of a nascent or mature glycoprotein differs from wild type. FYPO_relaxed.owl FYPO:0006278 biolink:NamedThing abnormal O-linked glycoprotein glycan structure A phenotype in which the structure of an O-linked glycan moiety of a nascent or mature glycoprotein differs from wild type. FYPO_relaxed.owl FYPO:0003293 biolink:NamedThing increased UDP-galactose transmembrane transport A cellular process phenotype observed in the vegetative growth phase of the life cycle in which UDP-galactose transmembrane transport occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0003634 biolink:NamedThing decreased U1 snRNP binding A molecular function phenotype in which U1 snRNP binding by a gene product is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003636 biolink:NamedThing decreased U2 snRNP binding A molecular function phenotype in which U2 snRNP binding by a gene product is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003301 biolink:NamedThing delayed onset of protein degradation via N-end rule pathway during meiosis A cellular process phenotype in which ubiquitin-dependent protein degradation via the N-end rule pathway begins later than normal during one or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0003330 biolink:NamedThing normal protein localization to new mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the new mitotic spindle pole body is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005216 biolink:NamedThing normal protein localization to mitotic spindle pole body during metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is normal (i.e. indistinguishable from wild type) during metaphase of mitosis. FYPO_relaxed.owl FYPO:0003316 biolink:NamedThing normal protein localization to growing cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the growing cell tip is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004467 biolink:NamedThing normal protein localization to cell tip during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell tip is normal (i.e. indistinguishable from wild type) during a cellular response to salt stress. FYPO_relaxed.owl FYPO:0005828 biolink:NamedThing normal protein transport along microtubule to cell tip during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cell tip is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007284 biolink:NamedThing normal protein localization to non-growing cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the non-growing cell tip is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003317 biolink:NamedThing decreased protein localization to growing cell tip, with protein distributed in plasma membrane or cortex A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to a growing cell tip is decreased, and the protein is also detected distributed throughout the plasma membrane and/or cell cortex. FYPO_relaxed.owl FYPO:0003318 biolink:NamedThing abolished galactose-specific flocculation during vegetative growth A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which galactose-specific flocculation does not occur. Galactose-specific flocculation is the non-sexual aggregation of cells, mediated via the binding of cell wall proteins on one cell to galactose residues on the other. FYPO_relaxed.owl FYPO:0003319 biolink:NamedThing increased mannose-specific flocculation A cell adhesion phenotype observed in the vegetative growth phase of the life cycle in which mannose-specific flocculation is increased. Mannose-specific flocculation is the non-sexual aggregation of cells, mediated via the binding of cell wall proteins on one cell to mannose residues on the other, and when it is increased cells adhere to each other more strongly or to a greater extent than normal. FYPO_relaxed.owl FYPO:0003326 biolink:NamedThing normal interphase microtubule nucleation A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of microtubules is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. Normally, microtubules are nucleated from interphase microtubule organizing centers (iMTOCs) and from the cytoplasmic face of the spindle pole body (SPB). FYPO_relaxed.owl FYPO:0006004 biolink:NamedThing normal interphase microtubule organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubule organization is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0008233 biolink:NamedThing microtubule bundles present in normal numbers A physical cellular phenotype in which cells contain a normal number of microtubule bundles. FYPO_relaxed.owl FYPO:0003327 biolink:NamedThing curved interphase microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are curved, i.e. follow a smooth bend rather than a straight line, during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0003332 biolink:NamedThing normal protein kinase activity during mitotic interphase A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004245 biolink:NamedThing normal protein kinase activity during mitotic S phase during cellular response to DNA damage A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during S phase of the mitotic cell cycle during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0004548 biolink:NamedThing normal protein kinase activity during cellular response to hydroxyurea A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0005717 biolink:NamedThing normal protein kinase activity during mitosis A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during mitosis. FYPO_relaxed.owl FYPO:0007728 biolink:NamedThing normal protein kinase activity during cellular response to osmotic stress A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during a cellular response to osmotic stress. FYPO_relaxed.owl FYPO:0007882 biolink:NamedThing normal protein kinase activity during cellular response to methyl methanesulfonate A molecular function phenotype in which the observed rate of a protein kinase activity is normal (i.e. indistinguishable from wild type) during a cellular response to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0004737 biolink:NamedThing decreased F-actin level in actomyosin contractile ring during early mitosis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount of filamentous actin (F-actin) in the actomyosin contractile ring is lower than normal during early mitosis (before anaphase). FYPO_relaxed.owl FYPO:0007898 biolink:NamedThing decreased actomyosin contractile ring actin filament length A cytokinesis phenotype observed in the vegetative growth phase of the life cycle in which the length of actin filaments in the contractile ring is shorter than normal. FYPO_relaxed.owl FYPO:0009103 biolink:NamedThing increased actomyosin contractile ring recoil distance after ring ablation A cell phenotype in which the recoil distance of the cytokynetic ring after ring ablation is increased with respect to wild type. Experimentally, a localised cut or ablation is typically achieved using a laser. This distance, in combination with the timing of recoil are used to compute effective stiffness and drag of the ring components. See PMID:36980258. FYPO_relaxed.owl FYPO:0009104 biolink:NamedThing increased actomyosin contractile ring recoil time after ring ablation A cell phenotype in which the recoil time of the cytokynetic ring after ring ablation is increased with respect to wild type. Experimentally, a localised cut or ablation is typically achieved using a laser. The recoil time is the time it takes the recoil to stop after laser ablation. This timing, in combination with the recoil distance are used to compute effective stiffness and drag of the ring components. See PMID:36980258. FYPO_relaxed.owl FYPO:0003348 biolink:NamedThing altered substrate specificity, glutathione synthetase to homoglutathione synthetase activity A molecular function phenotype in which the substrate specificity of a gene product that executes glutathione synthetase activity in wild type is altered such that the gene product executes homoglutathione synthetase activity. FYPO_relaxed.owl FYPO:0006450 biolink:NamedThing altered histone H3 acetyltransferase substrate specificity A molecular function phenotype in which the substrate specificity of a gene product that executes histone H3 acetyltransferase activity is altered. For example, preference for modified (e.g. methylated) H3 molecules may be enhanced or diminished. FYPO_relaxed.owl FYPO:0007076 biolink:NamedThing altered histone H3-K9 methyltransferase substrate specificity A molecular function phenotype in which the substrate specificity of a gene product that executes histone H3-K9 specific methyltransferase activity is altered. For example, preference for modified (e.g. ubiquitinated) H3 molecules may be enhanced or diminished. FYPO_relaxed.owl FYPO:0003349 biolink:NamedThing normal protein localization to mitotic spindle midzone during anaphase B A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during anaphase B is normal (i.e. indistinguishable from wild type). The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. Anaphase B is the stage of mitosis in which the polar microtubules elongate and the two poles of the spindle move farther apart. FYPO_relaxed.owl FYPO:0004692 biolink:NamedThing normal protein localization to mitotic spindle midzone A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006645 biolink:NamedThing normal protein localization to mitotic spindle midzone during metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during metaphase is normal (i.e. indistinguishable from wild type). The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. FYPO_relaxed.owl FYPO:0007124 biolink:NamedThing normal protein localization to mitotic spindle midzone during prophase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during prophase is normal (i.e. indistinguishable from wild type). The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. FYPO_relaxed.owl FYPO:0003350 biolink:NamedThing abolished protein localization to mitotic spindle midzone during anaphase B A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during anaphase B does not occur. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. Anaphase B is the stage of mitosis in which the polar microtubules elongate and the two poles of the spindle move farther apart. FYPO_relaxed.owl FYPO:0004412 biolink:NamedThing abolished protein localization to mitotic spindle midzone during anaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during anaphase does not occur. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. Anaphase is the stage of mitosis in which chromosomes separate and migrate towards the poles of the spindle. FYPO_relaxed.owl FYPO:0004832 biolink:NamedThing abolished protein localization to mitotic spindle midzone during anaphase A A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone during anaphase A does not occur. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. Anaphase A is the stage of mitosis in which the kinetochore microtubules shorten as chromosomes move toward the spindle poles. FYPO_relaxed.owl FYPO:0003366 biolink:NamedThing decreased pyridoxine import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of pyridoxine into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0003371 biolink:NamedThing abolished protein localization to actomyosin contractile ring, with protein mislocalized to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is abolished, and the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0003372 biolink:NamedThing RNA absent from cell during meiosis A cell phenotype in which the amount of RNA measured in a cell is too low to detect during one or both meiotic nuclear divisions. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0003379 biolink:NamedThing abolished meiosis II A cellular process phenotype in which the second meiotic nuclear division, in which two chromatids in each chromosome are normally separated, does not occur. FYPO_relaxed.owl FYPO:0007487 biolink:NamedThing abolished new meiotic spindle pole body insertion into nuclear envelope during meiosis II A cellular process phenotype in which insertion of the newly formed spindle pole body into the nuclear envelope does not occur during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0003380 biolink:NamedThing decreased frequency of meiosis I A cell population phenotype in which the frequency of occurrence of the first meiotic nuclear division, in which homologous chromosomes are normally paired and segregated from each other, is decreased. FYPO_relaxed.owl FYPO:0003789 biolink:NamedThing decreased frequency of meiosis II A cell population phenotype in which the frequency of occurrence of the second meiotic nuclear division, in which two chromatids in each chromosome are normally separated, is decreased. FYPO_relaxed.owl FYPO:0006167 biolink:NamedThing viable branched, swollen, elongated, multinucleate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is viable, branched, has more than one nucleus, and has a larger volume and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0003392 biolink:NamedThing decreased ubiquinone binding A molecular function phenotype in which occurrence of ubiquinone binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003395 biolink:NamedThing abolished mitochondrial electron transport, succinate to ubiquinone A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial electron transport from succinate to ubiquinone, mediated by complex II, does not occur. FYPO_relaxed.owl FYPO:0003397 biolink:NamedThing decreased 35S rRNA precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the 35S rRNA primary transcript measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0003398 biolink:NamedThing decreased 32S rRNA precursor level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any 32S rRNA precursor measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0003410 biolink:NamedThing increased spatial extent of CENP-A containing chromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) are assembled over a larger portion of the centromeric region of the chromosome than normal. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions. FYPO_relaxed.owl FYPO:0003740 biolink:NamedThing decreased CENP-A containing chromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the formation of chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) occurs to a lower extent than normal. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions. FYPO_relaxed.owl FYPO:0004322 biolink:NamedThing decreased spatial extent of CENP-A containing chromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) are assembled over a smaller portion of the centromeric region of the chromosome than normal. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions. FYPO_relaxed.owl FYPO:0005887 biolink:NamedThing ectopic CENP-A containing chromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) are assembled in one or more regions of the chromosome away from the centromere. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions. FYPO_relaxed.owl FYPO:0003411 biolink:NamedThing decreased chromatin silencing at centromere inner repeat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere inner repeat regions is decreased. FYPO_relaxed.owl FYPO:0003412 biolink:NamedThing decreased chromatin silencing at centromere outer repeat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere outer repeat regions is decreased. FYPO_relaxed.owl FYPO:0006299 biolink:NamedThing increased chromatin silencing at centromere outer repeat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere outer repeat regions is increased. FYPO_relaxed.owl FYPO:0007223 biolink:NamedThing decreased establishment of chromatin silencing at centromere outer repeat region A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the establishment of chromatin silencing at centromere outer repeat regions is decreased. FYPO_relaxed.owl FYPO:0007334 biolink:NamedThing abolished chromatin silencing at centromere outer repeat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing does not occur at centromere outer repeat regions. FYPO_relaxed.owl FYPO:0003422 biolink:NamedThing inviable after spore germination, multiple cell divisions, elongated multiseptate tapered cell A phenotype in which a spore germinates to produce a cell that is elongated and tapered, i.e. tapers at one end to a diameter smaller than the other, contains more than one septum, and undergoes two or more rounds of cell division and then dies. FYPO_relaxed.owl FYPO:0003420 biolink:NamedThing increased cellular glutathione level during cellular response to cadmium ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of glutathione (GSH) measured in a cell is higher than normal during a cellular response to cadmium. FYPO_relaxed.owl FYPO:0003421 biolink:NamedThing decreased cellular nitric oxide level during cellular response to cadmium ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of nitric oxide measured in a cell is lower than normal during a cellular response to cadmium. FYPO_relaxed.owl FYPO:0003429 biolink:NamedThing short interphase microtubules present in decreased numbers A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer, and shorter, cytoplasmic microtubules than normal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004733 biolink:NamedThing cytoplasmic microtubules nucleated from eMTOC present in decreased numbers A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell contains fewer cytoplasmic microtubules nucleated from the equatorial microtubule organizing center than normal. FYPO_relaxed.owl FYPO:0009102 biolink:NamedThing interphase microtubules present in decreased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain less cytoplasmic microtubules than normal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006103 biolink:NamedThing short interphase microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are shorter than normal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004539 biolink:NamedThing short interphase microtubules present in increased numbers A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains more, and shorter, cytoplasmic microtubules than normal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0003431 biolink:NamedThing abolished histone H3K9me binding A molecular function phenotype in which the binding of a protein to histone H3 methylated on the lysine at position 9 does not occur. FYPO_relaxed.owl FYPO:0003436 biolink:NamedThing decreased protein kinase activity during mitotic G2 phase A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during the G2 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004242 biolink:NamedThing decreased protein kinase activity during mitotic S phase A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during the S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006560 biolink:NamedThing decreased protein kinase activity during mitotic G1 phase A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during the G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0003437 biolink:NamedThing abolished protein kinase activity during mitotic G1 phase A molecular function phenotype in which a protein kinase activity is absent during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006440 biolink:NamedThing abolished protein kinase activity during cellular response to hydroxyurea A molecular function phenotype in which a protein kinase activity is absent during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0008263 biolink:NamedThing abolished protein kinase activity in response to osmotic stress A molecular function phenotype in which a protein kinase activity is absent during a cellular response to osmotic stress. FYPO_relaxed.owl FYPO:0008264 biolink:NamedThing abolished protein kinase activity in response to oxidative stress A molecular function phenotype in which a protein kinase activity is absent during a cellular response to oxidative stress. FYPO_relaxed.owl FYPO:0003438 biolink:NamedThing mitotic G1/S phase transition delay following nitrogen starvation-induced G1 phase arrest A cell cycle phenotype in which the G1/S transition of the mitotic cell cycle begins later than normal after the cell has been arrested in G1 phase due to nitrogen starvation. The duration of G1 arrest is thus longer than normal. FYPO_relaxed.owl FYPO:0006097 biolink:NamedThing increased protein localization to actin cable A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to actin cables is increased. FYPO_relaxed.owl FYPO:0003445 biolink:NamedThing increased duration of mitotic DNA damage checkpoint during cellular response to UV A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type during a cellular response to ultraviolet light. FYPO_relaxed.owl FYPO:0003461 biolink:NamedThing normal cellular trehalose level during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is normal (i.e. indistinguishable from wild type) when the cell is subject to salt stress. FYPO_relaxed.owl FYPO:0003462 biolink:NamedThing normal cellular trehalose level during cellular response to oxidative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is normal (i.e. indistinguishable from wild type) when the cell is subject to oxidative stress. FYPO_relaxed.owl FYPO:0003466 biolink:NamedThing normal cellular trehalose level during cellular response to heat A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of trehalose measured in a cell is normal (i.e. indistinguishable from wild type) when the cell is subject to a heat stimulus. FYPO_relaxed.owl FYPO:0003469 biolink:NamedThing normal snRNA splicing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which small nuclear RNA (snRNA) splicing is normal (i.e. indistinguishable from wild type). All snRNA splicing may be normal, or one splicing of or more specific snRNA molecules may be specifically assayed. FYPO_relaxed.owl FYPO:0003619 biolink:NamedThing normal mRNA splicing, via spliceosome A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mRNA splicing via the spliceosome is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003473 biolink:NamedThing septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation during cellular response to salt stress An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes septation despite abnormal chromosome segregation, producing inviable daughter cells, and in which the septum forms in a position that partitions both nuclei into one compartment, when the cell is subject to salt stress. Cell separation may or may not be completed. FYPO_relaxed.owl FYPO:0003823 biolink:NamedThing septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation during cellular response to hydroxyurea An inviable phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes septation despite abnormal chromosome segregation, producing inviable daughter cells, and in which the septum forms in a position that partitions both nuclei into one compartment, when a cell is exposed to hydroxyurea. Cell separation may or may not be completed. FYPO_relaxed.owl FYPO:0003474 biolink:NamedThing fragmented nucleus during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which nucleus is broken into multiple small fragments that are smaller than a normal nucleus, hen the cell is subject to salt stress. FYPO_relaxed.owl FYPO:0004196 biolink:NamedThing inviable after spore germination, single or double cell division, elongated multiseptate cell with fragmented nucleus A phenotype in which a spore germinates to produce a cell that is elongated, has more than one septum and a nucleus that is broken into multiple small fragments, and undergoes one or two rounds of cell division. FYPO_relaxed.owl FYPO:0003480 biolink:NamedThing queuosine absent from tRNA A phenotype in which one or more transfer RNA (tRNA) molecules contains no queuosine residues. FYPO_relaxed.owl FYPO:0003484 biolink:NamedThing abolished protein localization to mitotic spindle midzone A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone does not occur. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. FYPO_relaxed.owl FYPO:0003841 biolink:NamedThing decreased protein localization to mitotic spindle midzone A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone is decreased. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. FYPO_relaxed.owl FYPO:0004884 biolink:NamedThing increased duration of protein localization to mitotic spindle midzone A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the mitotic spindle midzone for a longer time than normal. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. FYPO_relaxed.owl FYPO:0003491 biolink:NamedThing sensitive to UV during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ultraviolet light during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005623 biolink:NamedThing sensitive to UV during late mitotic G2 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ultraviolet light late in G2 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005624 biolink:NamedThing sensitive to UV during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ultraviolet light during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0003498 biolink:NamedThing premature mitotic DNA replication initiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication begins earlier than normal. FYPO_relaxed.owl FYPO:0004475 biolink:NamedThing decreased mitotic DNA replication initiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication is decreased. Initiation may be affected at one or more origins. FYPO_relaxed.owl FYPO:0006031 biolink:NamedThing delayed onset of mitotic DNA replication initiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication begins later than normal. FYPO_relaxed.owl FYPO:0006272 biolink:NamedThing premature mitotic DNA replication initiation from late origin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication begins earlier than normal at origins that normally fire late. FYPO_relaxed.owl FYPO:0006400 biolink:NamedThing increased mitotic DNA replication initiation from inefficient origin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the frequency of DNA replication initiation is higher than normal at inefficient origins, i.e. replication origins that normally rarely fire. FYPO_relaxed.owl FYPO:0007233 biolink:NamedThing delayed onset of mitotic DNA replication initiation from early origin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication begins later than normal at origins that normally fire early. FYPO_relaxed.owl FYPO:0003525 biolink:NamedThing increased actin filament polymerization at cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the addition of actin monomers to a filament occurs to a greater extent than normal at one or both cell tips. FYPO_relaxed.owl FYPO:0003526 biolink:NamedThing decreased actin filament-based movement A cell phenotype observed in the vegetative growth phase of the life cycle in which actin filament-based movement is decreased. Actin filament-based movement is the movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. FYPO_relaxed.owl FYPO:0005901 biolink:NamedThing increased rate of actin filament-based movement A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin filament-based movement is increased. Actin filament-based movement is the movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. FYPO_relaxed.owl FYPO:0005902 biolink:NamedThing decreased rate of actin filament-based movement A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin filament-based movement is decreased. Actin filament-based movement is the movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. FYPO_relaxed.owl FYPO:0003536 biolink:NamedThing increased septation index in stationary phase A cell population phenotype in which the septation index is higher than normal in a population in stationary phase. The septation index is the proportion of the population undergoing septation at any given time. FYPO_relaxed.owl FYPO:0005671 biolink:NamedThing increased septation index during cellular response to methyl methanesulfonate A cell population phenotype in which the septation index is higher than normal in a population that is exposed to methyl methanesulfonate. The septation index is the proportion of the population undergoing septation at any given time. FYPO_relaxed.owl FYPO:0003538 biolink:NamedThing premature meiosis I A cellular process phenotype in which the first meiotic nuclear division begins earlier than normal. FYPO_relaxed.owl FYPO:0003790 biolink:NamedThing normal protein localization during meiosis A cell phenotype in which the localization of a protein in a cell is normal (i.e. indistinguishable from wild type) during the first or second meiotic nuclear division. FYPO_relaxed.owl FYPO:0006532 biolink:NamedThing normal protein localization to centromere during meiotic prophase II A cell phenotype in which the localization of a protein to the centromere of a chromosome is normal (i.e. indistinguishable from wild type) during prophase of the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0007167 biolink:NamedThing normal protein localization to cell cortex during meiotic prophase I A cell phenotype in which the localization of a protein to the cell cortex is normal (i.e. indistinguishable from wild type) during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007495 biolink:NamedThing normal protein localization to Mei2 nuclear dot A cell phenotype in which the localization of a protein to the Mei2 nuclear dot is normal (i.e. indistinguishable from wild type). The Mei2 nuclear dot is a nuclear body that contains Mei2, other proteins, and meiRNA, and forms during meiotic prophase in a fixed position in the horsetail nucleus. FYPO_relaxed.owl FYPO:0007687 biolink:NamedThing normal protein localization to nuclear exosome focus during meiosis A cell phenotype in which the localization of a protein to nuclear exosome foci is normal (i.e. indistinguishable from wild type) during meiosis. Nuclear exosome foci, also called Mmi1 foci, are small structures that form within the nucleus, and contain proteins involved in degrading meiosis-specific RNAs during the mitotic cell cycle. FYPO_relaxed.owl FYPO:0008193 biolink:NamedThing normal protein localization to pericentric heterochromatin during meiotic prophase I A cell phenotype in which the localization of a protein to pericentric heterochromatin is normal during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006457 biolink:NamedThing abolished protein localization to centromere central core during meiosis I A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the central core of the centromeric regions is abolished during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006773 biolink:NamedThing abolished protein localization to prospore septin ring A cell phenotype in which the localization of a protein to the prospore septin ring does not occur. FYPO_relaxed.owl FYPO:0008244 biolink:NamedThing abolished protein localization to prospore wall A cell phenotype in which a protein does not localize to, and is therefore absent from the prospore wall. FYPO_relaxed.owl FYPO:0007639 biolink:NamedThing increased DNA damage at rDNA during G0 A cell phenotype in which the amount of DNA damage measured at ribosomal DNA in a cell is greater than normal during G0 phase. The number, extent, or both of damage sites may be increased. FYPO_relaxed.owl FYPO:0007936 biolink:NamedThing increased number of DNA breakpoint junctions A cell phenotype in which the number of sites of DNA breakpoint junctions is greater than normal. FYPO_relaxed.owl FYPO:0003545 biolink:NamedThing increased duration of mitotic cell cycle DNA replication checkpoint A cell cycle checkpoint phenotype in which the duration of mitotic cell cycle arrest or delay due to regulation by the DNA replication checkpoint is greater than normal. The DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete. FYPO_relaxed.owl FYPO:0004360 biolink:NamedThing decreased duration of mitotic cell cycle DNA replication checkpoint A cell cycle checkpoint phenotype in which the duration of mitotic cell cycle arrest or delay due to regulation by the DNA replication checkpoint is shorter than normal. The DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete. FYPO_relaxed.owl FYPO:0005133 biolink:NamedThing decreased protein localization to ascospore wall A cell phenotype in which the localization of a protein to the ascospore wall is decreased. FYPO_relaxed.owl FYPO:0003550 biolink:NamedThing decreased protein level during meiosis A cell phenotype in which the amount of protein measured in a cell during one or both meiotic nuclear divisions is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004992 biolink:NamedThing decreased protein level during meiotic interphase A cell phenotype in which the amount of protein measured in a cell during interphase of the meiotic cell cycle is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003563 biolink:NamedThing normal meiosis I A cellular process phenotype in which the first meiotic nuclear division is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003798 biolink:NamedThing normal meiosis II A cellular process phenotype in which the second meiotic nuclear division is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004795 biolink:NamedThing normal zygotic meiosis A cellular process phenotype in which the meiotic nuclear divisions are normal (i.e. indistinguishable from wild type) during a cycle of zygotic meiosis and sporulation. Zygotic meiosis and sporulation take place under conditions of continuous nitrogen starvation, in which haploid cells of the opposite mating types conjugate to form diploid zygotes that proceed immediately to undergo meiosis and sporulation. FYPO_relaxed.owl FYPO:0004796 biolink:NamedThing normal azygotic meiosis A cellular process phenotype in which the meiotic nuclear divisions are normal (i.e. indistinguishable from wild type) during a cycle of azygotic meiosis and sporulation. Azygotic meiosis and sporulation occur when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell. FYPO_relaxed.owl FYPO:0003568 biolink:NamedThing abnormal mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in nucleoplasm A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the insertion of a spindle pole body (SPB) into the nuclear envelope is abnormal, and the SPB enters the nucleus. An open fenestra remains present in the nuclear envelope. FYPO_relaxed.owl FYPO:0003569 biolink:NamedThing abnormal mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in cytoplasm A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the insertion of a spindle pole body (SPB) into the nuclear envelope is abnormal, and the SPB enters the cytoplasm. An open fenestra remains present in the nuclear envelope. FYPO_relaxed.owl FYPO:0007426 biolink:NamedThing abolished new mitotic spindle pole body insertion into nuclear envelope A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the insertion of the newly assembled spindle pole body into the nuclear envelope does not occur. FYPO_relaxed.owl FYPO:0003574 biolink:NamedThing normal histone H3-K14 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere outer repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006817 biolink:NamedThing normal histone H3-K14 acetylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in centromere inner repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007219 biolink:NamedThing normal histone H3-K14 acetylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 in regions containing protein-coding genes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008209 biolink:NamedThing normal histone H3-K14 acetylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 14 of histone H3 is normal at the silent mating-type cassette (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003575 biolink:NamedThing normal histone H3-K9 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in centromere outer repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006395 biolink:NamedThing normal histone H3-K9 acetylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in heterochromatin at subtelomeric regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006816 biolink:NamedThing normal histone H3-K9 acetylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in centromere inner repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007220 biolink:NamedThing normal histone H3-K9 acetylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in regions containing protein-coding genes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003579 biolink:NamedThing normal RNA level during meiosis A cell phenotype in which the amount of RNA measured in a cell during one or both meiotic nuclear divisions is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0006146 biolink:NamedThing normal RNA level during cellular response to copper ion starvation during meiotic cell cycle A cell phenotype in which the amount of RNA measured in a cell during a cellular response to copper ion starvation and during the meiotic cell cycle is normal (i.e. indistinguishable from wild type). Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0003582 biolink:NamedThing increased number of Kms1 foci during response to DNA damage A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Kms1 accumulates is greater than normal during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0003596 biolink:NamedThing abnormal snRNA 3'-end processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of an snRNA molecule is abnormal. FYPO_relaxed.owl FYPO:0003686 biolink:NamedThing abnormal box C/D snoRNA 3'-end processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of a box C/D snoRNA molecule is abnormal. FYPO_relaxed.owl FYPO:0005909 biolink:NamedThing abnormal RNA 3'-end processing during cellular response to endoplasmic reticulum stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of an RNA molecule is abnormal during a cellular response to endoplasmic reticulum stress. FYPO_relaxed.owl FYPO:0006298 biolink:NamedThing abnormal 5.8S rRNA 3'-end processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of the 5.8S ribosomal RNA molecule is abnormal. FYPO_relaxed.owl FYPO:0008155 biolink:NamedThing abnormal regulatory lncRNA 3'-end processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which regulatory lncRNA 3' end processing is abnormal. FYPO_relaxed.owl FYPO:0003598 biolink:NamedThing decreased snRNA 3'-end processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which formation of the mature 3' end of an snRNA molecule is decreased. FYPO_relaxed.owl FYPO:0006852 biolink:NamedThing decreased duration of meiotic S phase A cellular process phenotype in which the duration of progression through S phase of the meiotic cell cycle (preceding meiosis I) is shorter than normal. FYPO_relaxed.owl FYPO:0003613 biolink:NamedThing normal meiotic sister chromatid cohesion during meiotic prophase I A cellular process phenotype in which cohesion between sister chromatids is normal (i.e. indistinguishable from wild type) during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0004667 biolink:NamedThing normal meiotic sister chromatid cohesion at centromere A cellular process phenotype in which cohesion between sister chromatids is normal (i.e. indistinguishable from wild type) at the centromeric regions during meiosis. FYPO_relaxed.owl FYPO:0007994 biolink:NamedThing normal meiotic sister chromatid cohesion protection during meiotic anaphase I A cellular process phenotype in which the cohesion protection during anaphase of the first meiotic nuclear division is normal. FYPO_relaxed.owl FYPO:0003614 biolink:NamedThing meiotic spindle absent from cell during meiosis II A cell phenotype in which the cell does not contain a detectable meiotic spindle during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0003699 biolink:NamedThing snoRNA guided rRNA pseudouridine synthesis abolished at specific site A cellular process phenotype in which the intramolecular conversion of uridine to pseudouridine does not occur at a specific site in an rRNA molecule that is normally modified. FYPO_relaxed.owl FYPO:0003720 biolink:NamedThing snoRNA guided rRNA 2'-O-methylation abolished at specific site A cellular process phenotype in which the 2'-O-methylation of a nucleotide residue does not occur at a specific site in an rRNA molecule that is normally modified. FYPO_relaxed.owl FYPO:0008110 biolink:NamedThing decreased U6 2'-O-snRNA methylation at residue A64 A cellular process phenotype observed in the vegetative growth phase of the life cycle in which posttranscriptional addition of a methyl group to the 2'-oxygen atom of the adenine residue at position 64 in an U6 snRNA molecule is decreased. FYPO_relaxed.owl FYPO:0003622 biolink:NamedThing abolished U6 2'-O-snRNA methylation at residue A41 A cellular process phenotype observed in the vegetative growth phase of the life cycle in which posttranscriptional addition of a methyl group to the 2'-oxygen atom of the adenine residue at position 41 in an U6 snRNA molecule is abolished. FYPO_relaxed.owl FYPO:0008109 biolink:NamedThing abolished U6 2'-O-snRNA methylation at residue A64 A cellular process phenotype observed in the vegetative growth phase of the life cycle in which posttranscriptional addition of a methyl group to the 2'-oxygen atom of the adenine residue at position 64 in an U6 snRNA molecule is abolished. FYPO_relaxed.owl FYPO:0003629 biolink:NamedThing abolished U2/U5/U6 snRNP complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spliceosomal tri-snRNP complex assembly is abolished. FYPO_relaxed.owl FYPO:0003631 biolink:NamedThing decreased U2-type prespliceosome assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which U2-type prespliceosome assembly is decreased. The U2-type prespliceosome is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP, and also contains other proteins. FYPO_relaxed.owl FYPO:0007069 biolink:NamedThing abnormal ribosomal small subunit assembly A cell phenotype observed in the vegetative growth phase of the life cycle in which assembly of the ribosomal small subunit is abnormal. FYPO_relaxed.owl FYPO:0008112 biolink:NamedThing abnormal U6 snRNP assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which any process of U6 snRNP complex assembly is abnormal. FYPO_relaxed.owl FYPO:0003638 biolink:NamedThing increased ADP binding A molecular function phenotype in which occurrence of ADP binding by a gene product (usually a protein) in a mutant is increased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003778 biolink:NamedThing decreased protein localization to endoplasmic reticulum tubular network A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum tubular network is decreased. FYPO_relaxed.owl FYPO:0006068 biolink:NamedThing increased protein localization to endoplasmic reticulum A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is increased. FYPO_relaxed.owl FYPO:0007443 biolink:NamedThing abolished protein localization to endoplasmic reticulum membrane, with protein mislocalized to cytosol A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is abolished, and the protein is present in the cytosol instead. FYPO_relaxed.owl FYPO:0007800 biolink:NamedThing abolished protein localization to endoplasmic reticulum, with protein mislocalized to cell surface A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum is abolished, and some of the protein is present at the cell surface instead. FYPO_relaxed.owl FYPO:0006585 biolink:NamedThing abolished protein localization to shmoo tip membrane, with protein mislocalized to endoplasmic reticulum A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is abolished, and the protein is present in the endoplasmic reticulum instead. FYPO_relaxed.owl FYPO:0006588 biolink:NamedThing decreased protein localization to shmoo tip membrane, with protein mislocalized to endoplasmic reticulum A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is decreased, and some of the protein is present in the endoplasmic reticulum instead. FYPO_relaxed.owl FYPO:0003658 biolink:NamedThing normal protein localization to Golgi membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the membrane of any part of the Golgi apparatus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003667 biolink:NamedThing abolished crossover junction endodeoxyribonuclease activity A molecular function phenotype in which crossover junction endodeoxyribonuclease activity is absent. FYPO_relaxed.owl FYPO:0003767 biolink:NamedThing decreased crossover junction endodeoxyribonuclease activity A molecular function phenotype in which the observed rate of crossover junction endodeoxyribonuclease activity is decreased. FYPO_relaxed.owl FYPO:0004029 biolink:NamedThing abolished 5' deoxyribonuclease (pyrimidine dimer) activity A molecular function phenotype in which 5' deoxyribonuclease (pyrimidine dimer) activity is absent. FYPO_relaxed.owl FYPO:0003668 biolink:NamedThing resistance to caffeine during cellular response to hydroxyurea An increased chemical resistance phenotype observed in the vegetative growth phase of the life cycle in which cells grow in the presence of a higher concentration of caffeine than normal during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0003669 biolink:NamedThing exon skipping A cellular process phenotype in which RNA splicing does not take place at a set of splice sites that are normally used, such that an exon is omitted from the mature RNA. FYPO_relaxed.owl FYPO:0007454 biolink:NamedThing decreased ATP binding A molecular function phenotype in which occurrence of ATP binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0003684 biolink:NamedThing altered level of macromolecular complex during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount of any macromolecular complex present in a cell differs from wild type. FYPO_relaxed.owl FYPO:0003685 biolink:NamedThing decreased U2/U5/U6 snRNP complex level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer U2/U5/U6 snRNP complexes than normal. FYPO_relaxed.owl FYPO:0003695 biolink:NamedThing decreased cytosolic small ribosomal subunit level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer free small ribosomal subunits in the cytosol than normal. FYPO_relaxed.owl FYPO:0003696 biolink:NamedThing increased cytosolic large ribosomal subunit level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more free large ribosomal subunits in the cytosol than normal. FYPO_relaxed.owl FYPO:0003732 biolink:NamedThing mitochondrial respiratory chain complex IV absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain any detectable respiratory chain complex IV in the mitochondria. FYPO_relaxed.owl FYPO:0004688 biolink:NamedThing decreased cytosolic large ribosomal subunit level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer free large ribosomal subunits in the cytosol than normal. FYPO_relaxed.owl FYPO:0004706 biolink:NamedThing decreased cytosolic monomeric ribosome level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer monomeric ribosomes (80S monosomes) in the cytosol than normal. FYPO_relaxed.owl FYPO:0004707 biolink:NamedThing increased cytosolic half-mer polysome level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more half-mer polysomes in the cytosol than normal. A half-mer polysome is a complex consisting of an mRNA bound to a single small ribosomal subunit, followed by one or more complete bound ribosomes. FYPO_relaxed.owl FYPO:0005711 biolink:NamedThing decreased cyclin B1-CDK1 complex level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer protein complexes consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1) than normal. FYPO_relaxed.owl FYPO:0005782 biolink:NamedThing decreased mitotic checkpoint complex level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer mitotic checkpoint complexes than normal. FYPO_relaxed.owl FYPO:0006036 biolink:NamedThing increased cytosolic monomeric ribosome level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more monomeric ribosomes (80S monosomes) in the cytosol than normal. FYPO_relaxed.owl FYPO:0006037 biolink:NamedThing decreased cytosolic half-mer polysome level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer half-mer polysomes in the cytosol than normal. A half-mer polysome is a complex consisting of an mRNA bound to a single small ribosomal subunit, followed by one or more complete bound ribosomes. FYPO_relaxed.owl FYPO:0007625 biolink:NamedThing mitochondrial respiratory chain complex III absent from cell A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which does not contain a detectable mitochondrial respiratory chain complex III. FYPO_relaxed.owl FYPO:0005714 biolink:NamedThing premature protein localization to nucleolus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus begins earlier than normal. FYPO_relaxed.owl FYPO:0006217 biolink:NamedThing increased protein localization to nucleolar periphery A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the border of the nuclear and nucleolar regions is increased. FYPO_relaxed.owl FYPO:0003689 biolink:NamedThing abolished protein localization to nucleolus, with protein mislocalized to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleolus is abolished, and the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0003698 biolink:NamedThing abnormal dense body present in nucleolus A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nucleolus contains one or more spherical structures of great electron density that are not found in wild type cells. FYPO_relaxed.owl FYPO:0003708 biolink:NamedThing normal frequency of conjugation with h+ cells A conjugation phenotype in which a normal proportion of cells in the population undergoes conjugation with wild type h+ cells. FYPO_relaxed.owl FYPO:0003797 biolink:NamedThing normal conjugation frequency A cell population phenotype in which a normal (i.e. indistinguishable from wild type) proportion of cells in the population undergoes conjugation. FYPO_relaxed.owl FYPO:0003714 biolink:NamedThing abolished protein localization to lateral cortical node, with protein mislocalized to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to Skb1-containing lateral cortical nodes is abolished, and the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0003715 biolink:NamedThing abolished protein localization to lateral cortical node, with protein distributed in plasma membrane or cortex A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to Skb1-containing lateral cortical nodes is abolished, and the protein is instead detected distributed throughout the plasma membrane and/or cell cortex. FYPO_relaxed.owl FYPO:0005515 biolink:NamedThing abolished protein localization to cell cortex, with protein mislocalized to vacuole, during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex is abolished, and the protein is present in the vacuole instead. FYPO_relaxed.owl FYPO:0007027 biolink:NamedThing abolished protein localization to medial cortex, with protein mislocalized to cytoplasm, during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex is abolished, and the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0003717 biolink:NamedThing normal actin cytoskeleton morphology during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the actin cytoskeleton is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003739 biolink:NamedThing decreased DNA replication origin binding A molecular function phenotype in which occurrence of DNA binding at a replication origin by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005018 biolink:NamedThing decreased double-stranded DNA binding A molecular function phenotype in which occurrence of double-stranded DNA binding by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0004142 biolink:NamedThing decreased RNA polymerase II proximal promoter sequence-specific DNA binding A molecular function phenotype in which DNA binding at an RNA polymerase II proximal promoter by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. An RNA polymerase II proximal promoter is a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II. FYPO_relaxed.owl FYPO:0004290 biolink:NamedThing decreased microsatellite DNA binding A molecular function phenotype in which occurrence of DNA binding at microsatellite repeat regions by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006622 biolink:NamedThing decreased T-G mismatch DNA binding A molecular function phenotype in which occurrence of binding to double-stranded DNA containing a G/T mispair by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007203 biolink:NamedThing decreased rDNA spacer replication fork barrier binding A molecular function phenotype in which occurrence of DNA binding at an rDNA spacer replication fork barrier by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006706 biolink:NamedThing abolished calcium-transporting ATPase activity A molecular function phenotype in which a calcium-transporting ATPase activity is absent. FYPO_relaxed.owl FYPO:0003747 biolink:NamedThing normal level of DSR-containing meiotic gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more RNAs that are normally expressed during meiosis, and that contain determinant of selective removal (DSR) sequences, measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003749 biolink:NamedThing abolished positive regulation of m7G(5')pppN diphosphatase activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of m7G(5')pppN diphosphatase activity does not occur. FYPO_relaxed.owl FYPO:0004387 biolink:NamedThing decreased positive regulation of DNA-directed DNA polymerase activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of DNA-directed DNA polymerase activity occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004917 biolink:NamedThing decreased positive regulation of protein kinase activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of a protein kinase activity occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005199 biolink:NamedThing decreased negative regulation of protein kinase activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of a protein kinase activity occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005204 biolink:NamedThing increased positive regulation of DNA-directed DNA polymerase activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of DNA-directed DNA polymerase activity occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005715 biolink:NamedThing delayed activation of protein kinase activity during mitosis A regulation phenotype observed in the vegetative growth phase of the life cycle in which activation of an inactive protein kinase activity begins later than normal during mitosis. FYPO_relaxed.owl FYPO:0005716 biolink:NamedThing delayed negative regulation of protein kinase activity during mitosis A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of a protein kinase activity begins later than normal during mitosis. FYPO_relaxed.owl FYPO:0007360 biolink:NamedThing decreased positive regulation of ATPase activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of an ATPase activity occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0008027 biolink:NamedThing increased rate of acid phosphatase activation during phosphate starvation A regulation phenotype observed in the vegetative growth phase of the life cycle in which the rate of acid phosphatase activation during phosphate starvation is increased. FYPO_relaxed.owl FYPO:0008028 biolink:NamedThing decreased rate of acid phosphatase activation during phosphate starvation A regulation phenotype observed in the vegetative growth phase of the life cycle in which the rate of acid phosphatase activation during phosphate starvation is decreased. FYPO_relaxed.owl FYPO:0003752 biolink:NamedThing increased total nuclear polyadenylated mRNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of polyadenylated messenger RNA (mRNA) measured in the nucleus is higher than normal. FYPO_relaxed.owl FYPO:0003753 biolink:NamedThing increased specific nuclear polyadenylated mRNA level during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more specific polyadenylated messenger RNAs (mRNAs) measured in the nucleus is higher than normal. FYPO_relaxed.owl FYPO:0003784 biolink:NamedThing inviable after spore germination, single or double cell division, arrest with septated mononucleate cell A phenotype in which a spore germinates to produce a cell of normal morphology that undergoes one or two rounds of cell division, and all cells produced arrest the cell cycle with a septum and a nucleus in one compartment, and then die. FYPO_relaxed.owl FYPO:0004030 biolink:NamedThing decreased 5' deoxyribonuclease (pyrimidine dimer) activity A molecular function phenotype in which the observed rate of 5' deoxyribonuclease (pyrimidine dimer) activity is decreased. FYPO_relaxed.owl FYPO:0003769 biolink:NamedThing decreased cellular mtDNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mitochondrial DNA present in the cell is lower than normal. FYPO_relaxed.owl FYPO:0004275 biolink:NamedThing abnormal positive regulation of transcription during G0 A transcription regulation phenotype in which any process of positive regulation of transcription is abnormal during G0 phase. FYPO_relaxed.owl FYPO:0006379 biolink:NamedThing abolished protein localization to endoplasmic reticulum during nitrogen starvation A cell phenotype in which the localization of a protein to the nucleus does not occur when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0003783 biolink:NamedThing abnormal nuclear pore localization during mitosis A localization phenotype observed in the vegetative growth phase of the life cycle in which nuclear pore localization is abnormal, resulting in an abnormal spatial arrangement of nuclear pores within the nuclear envelope, during mitosis. FYPO_relaxed.owl FYPO:0003974 biolink:NamedThing nuclear pore aggregation in cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more clusters of nuclear pores, associated with membrane fragments derived from the nuclear envelope, are present in the cytoplasm. FYPO_relaxed.owl FYPO:0003978 biolink:NamedThing inviable vegetative cell with fragmented nuclear envelope and nuclear pore aggregation in cytoplasm during mitotic telophase A cell morphology phenotype in which a vegetatively growing cell is inviable, and has a nuclear envelope that is broken into multiple small fragments and one or more clusters of nuclear pores present in the cytoplasm during mitotic telophase. FYPO_relaxed.owl FYPO:0003786 biolink:NamedThing abolished protein localization to centromere central core during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the central core of the centromeric regions is abolished. FYPO_relaxed.owl FYPO:0003788 biolink:NamedThing nuclear envelope protrusion present during mitosis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear envelope has one or more extensions that protrude into the cytoplasm during mitosis. FYPO_relaxed.owl FYPO:0007459 biolink:NamedThing abnormal nuclear envelope morphology at mitotic nuclear bridge A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the portion of the nuclear envelope enclosing the mitotic nuclear bridge is abnormal. The nuclear bridge is a narrow constricted region of the nucleus that forms around the mitotic spindle during anaphase. FYPO_relaxed.owl FYPO:0006774 biolink:NamedThing normal protein localization to prospore septin ring A cell phenotype in which the localization of a protein to the prospore septin ring is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003896 biolink:NamedThing normal mitochondrial morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the mitochondrion is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006035 biolink:NamedThing normal mitochondrial membrane potential A physical cellular phenotype in which the mitochondrial membrane potential, i.e. the electric potential existing across the mitochondrial membrane, is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003810 biolink:NamedThing small fragmented mitochondria present in increased numbers A cell phenotype observed in the vegetative growth phase of the life cycle in which mitochondria are smaller and more numerous than normal. Total mitochondrial volume is usually similar to normal. FYPO_relaxed.owl FYPO:0007611 biolink:NamedThing small fragmented mitochondria present in decreased numbers A cell phenotype observed in the vegetative growth phase of the life cycle in which mitochondria are smaller, and the total number of mitochondria in the cell is lower, than normal. Total mitochondrial volume is therefore lower than normal normal. FYPO_relaxed.owl FYPO:0007210 biolink:NamedThing normal mitochondrial volume A cell phenotype observed in the vegetative growth phase of the life cycle in which the total volume of all mitochondria in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003811 biolink:NamedThing asymmetric mitochondrial aggregation An abnormal intracellular mitochondrion distribution phenotype observed in the vegetative growth phase of the life cycle in which mitochondria cluster together more than normal with a cluster distal to only one side of the nucleus. FYPO_relaxed.owl FYPO:0003897 biolink:NamedThing mitochondrial aggregation during cellular response to reactive oxygen species An abnormal intracellular mitochondrion distribution phenotype observed in the vegetative growth phase of the life cycle in which mitochondria cluster together more than normal during a cellular response to reactive oxygen species. FYPO_relaxed.owl FYPO:0005838 biolink:NamedThing symmetric mitochondrial aggregation An abnormal intracellular mitochondrion distribution phenotype observed in the vegetative growth phase of the life cycle in which mitochondria cluster together more than normal with a cluster distal to each side of the nucleus. FYPO_relaxed.owl FYPO:0003812 biolink:NamedThing abnormal nucleosome positioning at stress response genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning is abnormal near the promoter regions of genes that are expressed in response to stress. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another. FYPO_relaxed.owl FYPO:0007833 biolink:NamedThing abnormal nucleosome positioning at protein-coding gene A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning is abnormal in regions containing protein-coding genes. FYPO_relaxed.owl FYPO:0003813 biolink:NamedThing normal nucleosome positioning at stress response genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome positioning is normal (i.e. indistinguishable from wild type) near the promoter regions of genes that are expressed in response to stress. Nucleosome positioning is the ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another. FYPO_relaxed.owl FYPO:0005952 biolink:NamedThing normal nucleosome occupancy at highly transcribed RNA polymerase II genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is normal (i.e. indistinguishable from wild type) in chromatin regions where RNA polymerase II actively transcribes genes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0003815 biolink:NamedThing decreased response to S-phase DNA damage checkpoint signaling A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the S phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is decreased. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0006436 biolink:NamedThing abnormal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate A cell cycle checkpoint phenotype in which the S-phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is abnormal when the cell is exposed to methyl methanesulfonate. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. FYPO_relaxed.owl FYPO:0008162 biolink:NamedThing increased activation of S-phase DNA damage checkpoint A cell cycle checkpoint phenotype in which the incidence of mitotic cell cycle arrest or delay due to regulation by the mitotic S-phase DNA damage checkpoint is greater than in wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0006006 biolink:NamedThing inviable binucleate aseptate cell with cell cycle arrest in mitotic telophase A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable and has two nuclei but no septum, and the mitotic cell cycle is arrested in telophase. The post-anaphase microtubule array is present. FYPO_relaxed.owl FYPO:0003826 biolink:NamedThing inviable elongated binucleate aseptate cell with cell cycle arrest at mitotic G2/M phase transition before cell separation A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, is elongated, has two nuclei but no septum, and the mitotic cell cycle is arrested with nuclei at the mitotic G2/M phase transition. FYPO_relaxed.owl FYPO:0003831 biolink:NamedThing abolished response to cytokinesis checkpoint signaling A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the cytokinesis after mitosis checkpoint does not occur. The cytokinesis after mitosis checkpoint normally delays the G2/M transition of a mitotic cell cycle if cytokinesis was not completed correctly in the previous cell cycle. Abolished arrest may result from a problem with detection of conditions that normally trigger a checkpoint, transduction of the checkpoint signal, or the response to the checkpoint signal. FYPO_relaxed.owl FYPO:0003837 biolink:NamedThing increased RNA polymerase II carboxy-terminal domain kinase activity A molecular function phenotype in which the observed rate of RNA polymerase II carboxy-terminal domain kinase activity is increased. FYPO_relaxed.owl FYPO:0004319 biolink:NamedThing increased cyclin-dependent protein kinase activity A molecular function phenotype in which the observed rate of a cyclin-dependent protein kinase activity is increased. FYPO_relaxed.owl FYPO:0006441 biolink:NamedThing increased protein kinase activity during cellular response to hydroxyurea A molecular function phenotype in which the observed rate of a protein kinase activity is increased during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0007183 biolink:NamedThing increased protein kinase activity during mitotic interphase A molecular function phenotype in which the observed rate of a protein kinase activity is increased during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007184 biolink:NamedThing increased protein kinase activity during mitosis A molecular function phenotype in which the observed rate of a protein kinase activity is increased during mitosis. FYPO_relaxed.owl FYPO:0007729 biolink:NamedThing decreased protein localization to mitotic spindle during anaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle is decreased during anaphase. FYPO_relaxed.owl FYPO:0003847 biolink:NamedThing h- specific sterility A cellular process phenotype in which conjugation does not occur in cells of the h- mating type. FYPO_relaxed.owl FYPO:0004174 biolink:NamedThing h+ specific sterility A cellular process phenotype in which conjugation does not occur in cells of the h+ mating type. FYPO_relaxed.owl FYPO:0003867 biolink:NamedThing increased level of ubiquitinated protein in cell during G0 A cell phenotype in which the amount of ubiquitinated protein measured in the cell is higher than normal when the cell is in G0 phase. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0003869 biolink:NamedThing increased level of hydrogen peroxide-induced proteins during G0 A cell phenotype observed in which the amount of protein encoded by genes normally induced by exposure to hydrogen peroxide measured in a cell is higher than normal when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0003870 biolink:NamedThing increased level of cadmium-induced proteins during G0 A cell phenotype observed in which the amount of protein encoded by genes normally induced by exposure to cadmium ions measured in a cell is higher than normal when the cell is in G0 phase. FYPO_relaxed.owl FYPO:0003888 biolink:NamedThing increased cell wall thickness at new end during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is thicker than normal at the new end of the cell. FYPO_relaxed.owl FYPO:0003889 biolink:NamedThing decreased cell wall thickness at old end during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is thinner than normal at the old end of the cell. FYPO_relaxed.owl FYPO:0006746 biolink:NamedThing decreased cell wall thickness at cell tip during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the fungal-type cell wall is thinner than normal at one or both cell tips. FYPO_relaxed.owl FYPO:0003893 biolink:NamedThing abolished incorporation of ATP opposite 8-oxo-dG A cellular process phenotype in which the insertion of ATP opposite an 8-oxo-7,8-dihydroguanosine (8oxodG) residue in DNA does not occur. Normally, if a guanosine residue is damaged to form 8oxodG, ATP can be misincorporated into the opposite strand to form an 8oxodG:AMP mispair that is subsequently removed. FYPO_relaxed.owl FYPO:0004436 biolink:NamedThing increased error-prone translesion synthesis A cell phenotype observed in the vegetative growth phase of the life cycle in which error-prone translesion synthesis occurs to a greater extent than normal. Error-prone translesion synthesis a DNA repair process that results in the conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. FYPO_relaxed.owl FYPO:0005331 biolink:NamedThing decreased error-prone translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of pyrimidine-pyrimidone 6-4 photoproducts by error-prone translesion synthesis occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005332 biolink:NamedThing abolished error-prone translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of pyrimidine-pyrimidone 6-4 photoproducts by error-prone translesion synthesis does not occur. FYPO_relaxed.owl FYPO:0003908 biolink:NamedThing increased stress response gene antisense RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from antisense transcription of genes that are expressed in response to stress measured in a cell is greater than normal. All stress-responsive genes, or a specific subset of such genes, may be affected. FYPO_relaxed.owl FYPO:0004815 biolink:NamedThing increased rDNA antisense siRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of siRNA derived from antisense transcription of ribosomal DNA measured in a cell is greater than normal. FYPO_relaxed.owl FYPO:0003909 biolink:NamedThing increased nucleosome occupancy at CRE site A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is greater than normal at promoters containing CRE sites. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0006309 biolink:NamedThing increased nucleosome occupancy at FLEX element A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is greater than normal at promoters containing FLEX elements. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0004287 biolink:NamedThing decreased double-strand break repair via nonhomologous end joining A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of double-strand break repair via nonhomologous end joining (NHEJ) is decreased. NHEJ is the repair of double-strand breaks in DNA in which the two broken ends are rejoined with little or no sequence complementarity. FYPO_relaxed.owl FYPO:0003918 biolink:NamedThing abolished nonsense-mediated decay A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the degradation of messenger RNA (mRNA) molecules that contain nonsense mutations does not occur. FYPO_relaxed.owl FYPO:0003919 biolink:NamedThing abolished protein localization to medial cortical node A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is abolished. FYPO_relaxed.owl FYPO:0007177 biolink:NamedThing abolished protein localization to medial cortex during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is abolished during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007178 biolink:NamedThing abolished protein localization to medial cortex during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortex of a cell is abolished during mitosis. FYPO_relaxed.owl FYPO:0006326 biolink:NamedThing decreased protein localization to medial cortical node A cell phenotype in which the localization of a protein to the medial cortical nodes is decreased in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0007156 biolink:NamedThing increased protein localization to medial cortical node A cell phenotype in which the localization of a protein to the medial cortical nodes is increased in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0007575 biolink:NamedThing decreased duration of protein localization to medial cortical node A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to the medial cortical nodes for a shorter time than normal. FYPO_relaxed.owl FYPO:0007830 biolink:NamedThing narrow protein radial density distribution in medial cortical node during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein located in the medial cortical nodes occupies an area with a smaller radius than normal during interphase of the mitotic cell cycle. The nodes are "precursor" nodes that exist before the contractile ring is formed. FYPO_relaxed.owl FYPO:0007831 biolink:NamedThing narrow protein radial density distribution in medial cortical node during mitotic anaphase B A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein located in the medial cortical nodes occupies an area with a smaller radius than normal during anaphase B of mitosis. The nodes are "ring" nodes, observed when the contractile ring is constricting. FYPO_relaxed.owl FYPO:0004844 biolink:NamedThing abnormal mitotic DNA replication lagging strand elongation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which lagging strand elongation during nuclear DNA replication is abnormal. FYPO_relaxed.owl FYPO:0006731 biolink:NamedThing decreased CMG complex progression from replication origin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the CMG complex moves away from replication origins to a lesser extent than normal. FYPO_relaxed.owl FYPO:0007814 biolink:NamedThing increased rate of mitotic DNA replication elongation during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA strand elongation involved in mitotic nuclear DNA replication is increased during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0003925 biolink:NamedThing decreased rate of mitotic DNA replication elongation at highly transcribed RNA polymerase II genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA strand elongation involved in mitotic nuclear DNA replication is decreased in regions where RNA polymerase II actively transcribes genes. FYPO_relaxed.owl FYPO:0005763 biolink:NamedThing increased replication fork pausing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork pausing occurs to a greater extent than normal, including at sites where forks do not normally pause. FYPO_relaxed.owl FYPO:0003932 biolink:NamedThing normal nuclear 5'-3' exonucleolytic mRNA catabolic process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which an exonucleolytic RNA catabolic process that proceeds in the 5' to 3' direction to degrade mRNA encoded in the nucleus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0003935 biolink:NamedThing decreased protein localization to Golgi apparatus, with protein mislocalized to endoplasmic reticulum A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is decreased, and the protein is present in the endoplasmic reticulum instead. FYPO_relaxed.owl FYPO:0004786 biolink:NamedThing decreased protein localization to Golgi apparatus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is decreased. FYPO_relaxed.owl FYPO:0007488 biolink:NamedThing decreased protein localization to Golgi apparatus, with protein mislocalized to vacuole A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is decreased, and the protein is present in the vacuole instead. FYPO_relaxed.owl FYPO:0007489 biolink:NamedThing decreased protein localization to Golgi apparatus, with protein mislocalized to cytosol A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the Golgi apparatus is decreased, and the protein is present in the cytosol instead. FYPO_relaxed.owl FYPO:0003945 biolink:NamedThing increased RNA catabolic process during cellular response to hydrogen peroxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of an RNA catabolic process is increased during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0006877 biolink:NamedThing inviable after spore germination, multiple cell divisions, cell lysis during cytokinesis A phenotype in which a spore germinates to produce an inviable cell that undergoes two or more rounds of cell division, but then lyses during cytokinesis and dies. FYPO_relaxed.owl FYPO:0003979 biolink:NamedThing abnormal mitotic cell cycle arrest with condensed chromosomes, septated cell with 1C DNA content per nucleus A cellular process phenotype in which progression through the mitotic cell cycle is arrested when cells have condensed chromosomes, a single, normally located septum, and 1C DNA content in each nucleus, under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0004719 biolink:NamedThing abnormal mitotic cell cycle arrest with condensed chromosomes, septated cell A cellular process phenotype in which progression through the mitotic cell cycle is arrested when cells have condensed chromosomes and a single, normally located septum, under conditions where arrest does not normally occur. FYPO_relaxed.owl FYPO:0006772 biolink:NamedThing dispersed actin cortical patch localization during mating A physical cellular phenotype in which actin cortical patches are localized throughout the cell cortex during mating. Normally, actin cortical patches concentrate in the mating projection tip and conjugation bridge during cell fusion, and then disperse after karyogamy. FYPO_relaxed.owl FYPO:0003990 biolink:NamedThing sensitive to DNA damage during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to DNA damage during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004011 biolink:NamedThing increased degradation of ribosomal proteins during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of degradation of one or more ribosomal proteins is increased. FYPO_relaxed.owl FYPO:0004199 biolink:NamedThing increased protein degradation during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is increased during mitosis. FYPO_relaxed.owl FYPO:0004200 biolink:NamedThing increased protein degradation during mitotic G1 phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is increased during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004016 biolink:NamedThing normal cellular mtDNA level A cell phenotype in which the amount of mitochondrial DNA measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004018 biolink:NamedThing normal mitochondrial electron transport, NADH to ubiquinone A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial electron transport from NADH to ubiquinone is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004019 biolink:NamedThing normal mitochondrial electron transport, succinate to ubiquinone A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial electron transport from succinate to ubiquinone is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004022 biolink:NamedThing abnormal cell cycle arrest in mitotic metaphase with long polar microtubules A cellular process phenotype in which progression through the mitotic cell cycle is arrested in metaphase under conditions where arrest does not normally occur, with polar microtubules that are longer than normal. FYPO_relaxed.owl FYPO:0005321 biolink:NamedThing inviable elongated mononucleate aseptate cell with cell cycle arrest in mitotic metaphase A cell morphology phenotype in which a vegetative cell is inviable contains one nucleus, has no septum, is elongated, and progression through the mitotic cell cycle is arrested in mitotic metaphase. FYPO_relaxed.owl FYPO:0007303 biolink:NamedThing abnormal cell cycle arrest in mitotic metaphase with condensed chromosomes A cellular process phenotype in which progression through the mitotic cell cycle is arrested in metaphase under conditions where arrest does not normally occur, and in which chromosomes remain condensed. FYPO_relaxed.owl FYPO:0004024 biolink:NamedThing normal protein localization to cytoplasmic stress granule A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to cytoplasmic stress granules is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004063 biolink:NamedThing normal protein localization to cytoplasm during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to all or part of the cytoplasm is normal (i.e. indistinguishable from wild type) during a cellular response to salt stress. FYPO_relaxed.owl FYPO:0008234 biolink:NamedThing normal protein localization to cytoplasmic puncta A cell phenotype in which a protein is localized to discrete regions in the cytoplasm, visible as foci or dots by microscopy, to the same extent as observed in normal (wild type) cells. FYPO_relaxed.owl FYPO:0004026 biolink:NamedThing loss of template switch-mediated chromosomal rearrangement during replication fork processing A cell phenotype in which the increase in gross chromosomal rearrangements that normally results from synthesis template switching during processing of arrested replication forks is diminished or abolished. FYPO_relaxed.owl FYPO:0004032 biolink:NamedThing increased protein localization to chromatin at rDNA A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at ribosomal DNA repeat regions is increased. FYPO_relaxed.owl FYPO:0004033 biolink:NamedThing increased protein localization to chromatin at tRNA genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at tRNA genes is increased. FYPO_relaxed.owl FYPO:0004038 biolink:NamedThing delayed onset of increase in RNA level during cellular response to hydrogen peroxide A cell phenotype in which an increase in RNA level that occurs as part of a cellular response to hydrogen peroxide begins later than normal. Total RNA or a specific RNA, such as the mRNA transcribed from a gene of interest, may be affected. FYPO_relaxed.owl FYPO:0004042 biolink:NamedThing fragmented septum A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms pieces of a septum rather than a septum that completely bisects the cell. FYPO_relaxed.owl FYPO:0004654 biolink:NamedThing thin, incomplete secondary cell septum A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a secondary septum that is thinner than normal and does not extend over the entire cell division site. FYPO_relaxed.owl FYPO:0005840 biolink:NamedThing incomplete, asymmetric septum A septation phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a septum that does not have uniform thickness and does not extend over the entire cell division site. FYPO_relaxed.owl FYPO:0005871 biolink:NamedThing thin, incomplete primary cell septum A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell forms a primary septum that is thinner than normal and does not extend over the entire cell division site. FYPO_relaxed.owl FYPO:0004045 biolink:NamedThing elongated tetranucleate vegetative cell with fragmented septum A cell morphology phenotype in which vegetative a cell is elongated, and contains four nuclei and pieces of a septum that does not completely bisect the cell. FYPO_relaxed.owl FYPO:0004050 biolink:NamedThing decreased glutathione transferase activity during stationary phase A molecular function phenotype in which the observed rate of glutathione transferase activity is decreased in a cell culture in stationary phase. FYPO_relaxed.owl FYPO:0004051 biolink:NamedThing increased glutathione transferase activity during stationary phase A molecular function phenotype in which the observed rate of glutathione transferase activity is increased in a cell culture in stationary phase. FYPO_relaxed.owl FYPO:0004052 biolink:NamedThing RNA absent from cell during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell is too low to detect during a cellular response to hydrogen peroxide. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004055 biolink:NamedThing decreased protein localization to nucleus during cellular response to salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased during a cellular response to salt stress. FYPO_relaxed.owl FYPO:0004059 biolink:NamedThing normal meiotic recombination at CRE promoter A cellular process phenotype in which reciprocal meiotic recombination is normal (i.e. indistinguishable from wild type) at an CRE promoter in a chromosome. FYPO_relaxed.owl FYPO:0005657 biolink:NamedThing normal frequency of meiotic crossover associated with gene conversion A cellular process phenotype in which the frequency of crossover associated with a gene conversion event during meiotic recombination is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005935 biolink:NamedThing normal meiotic recombination frequency A cellular process phenotype in which the frequency of occurrence of meiotic recombination is normal (i.e. indistinguishable from wild type). Meiotic recombination is a cellular process in which double strand breaks are formed and repaired through a double Holliday junction intermediate, resulting in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. FYPO_relaxed.owl FYPO:0004062 biolink:NamedThing increased duration of protein phosphorylation during cellular response to salt stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of protein phosphorylation is longer than normal during a cellular response to salt stress. All phosphorylation may be affected, or only phosphorylation of specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0005038 biolink:NamedThing abolished phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during nitrogen starvation A cellular process phenotype in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II does not occur when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0005039 biolink:NamedThing decreased phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during nitrogen starvation A cellular process phenotype in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II occurs to a lower extent than normal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0007411 biolink:NamedThing abnormal distribution of RNA polymerase II C-terminal domain residue phosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of residues within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II is abnormal, resulting in an abnormal distribution of RNA polymerase II molecules with different C-terminal domain residue phosphorylation patterns. FYPO_relaxed.owl FYPO:0008061 biolink:NamedThing abolished phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of the serine residue at position 5 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II does not occur. FYPO_relaxed.owl FYPO:0006210 biolink:NamedThing decreased RNA level during cellular response to copper ion starvation during spore germination A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to copper ion starvation is lower than normal during spore germination. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004073 biolink:NamedThing two cell divisions prior to cell cycle arrest in mitotic G1 phase in response to pheromone A cellular process phenotype in which the occurrence of cell cycle arrest in response to a pheromone occurs in G1 phase, but begins only after the cells have undergone two rounds of cell division in the presence of the pheromone. FYPO_relaxed.owl FYPO:0004974 biolink:NamedThing normal telomere localization during mitotic interphase A cellular process phenotype in which telomere localization, a process in which a telomere is transported to, and/or maintained in, a specific location, is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007417 biolink:NamedThing normal telomere clustering during G0 A cellular process phenotype in which telomere clustering is normal (i.e. indistinguishable from wild type) during G0 phase. Normally, telomeres cluster at the nuclear periphery during vegetative growth or G0, but whereas telomeres form two to three clusters in vegetative cells, a single cluster forms in G0. FYPO_relaxed.owl FYPO:0004101 biolink:NamedThing lagging mitotic chromosomes, with complete sister chromatid separation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which sister chromatids do not move towards the spindle poles at the same time during mitosis prior to completion of chromosome segregation. Although one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated, mitotic sister chromatid segregation does eventually go on to complete separation of chromosomes. FYPO_relaxed.owl FYPO:0004102 biolink:NamedThing decreased protein polyubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of polyubiquitination of one or more specific proteins, or of specific protein sites, is decreased. FYPO_relaxed.owl FYPO:0005813 biolink:NamedThing normal protein localization to microtubule end during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or both ends of a microtubule is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005827 biolink:NamedThing normal protein transport along microtubule during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004125 biolink:NamedThing abolished histone H3-K4 dimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 4 of histone H3 does not occur. FYPO_relaxed.owl FYPO:0004126 biolink:NamedThing abolished histone H3-K4 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 4 of histone H3 does not occur. FYPO_relaxed.owl FYPO:0004129 biolink:NamedThing increased cysteine-type peptidase activity A molecular function phenotype in which the observed rate of a cysteine-type peptidase activity is increased. FYPO_relaxed.owl FYPO:0005113 biolink:NamedThing increased ubiquitin-specific protease activity A molecular function phenotype in which the observed rate of ubiquitin-specific protease activity is increased. FYPO_relaxed.owl FYPO:0006090 biolink:NamedThing increased glutathione hydrolase activity A molecular function phenotype in which the observed rate of glutathione hydrolase activity is increased. FYPO_relaxed.owl FYPO:0005285 biolink:NamedThing decreased cysteine-type endopeptidase activity A molecular function phenotype in which the observed rate of a cysteine-type endopeptidase activity is decreased. FYPO_relaxed.owl FYPO:0004136 biolink:NamedThing abolished histone H3-K9 dimethylation at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in telomeric regions does not occur. FYPO_relaxed.owl FYPO:0004170 biolink:NamedThing abolished histone H3-K9 dimethylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in centromeric regions does not occur. FYPO_relaxed.owl FYPO:0006111 biolink:NamedThing abolished histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in subtelomeric regions does not occur. FYPO_relaxed.owl FYPO:0004144 biolink:NamedThing decreased catalase activity during cellular response to nitrosative stress A molecular function phenotype in which the observed rate of catalase activity is decreased during a cellular response to nitrosative stress. FYPO_relaxed.owl FYPO:0004158 biolink:NamedThing elongated vegetative cell with fragmented septum and more than four nuclei A cell morphology phenotype in which vegetative a cell is elongated, and contains more than four nuclei and pieces of a septum that does not completely bisect the cell. FYPO_relaxed.owl FYPO:0008044 biolink:NamedThing swollen elongated multinucleate aseptate vegetative cell with more than four nuclei A cell morphology phenotype in which a vegetative cell is swollen, elongated, has no septum, and contains more than four nucleus. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0004160 biolink:NamedThing normal meiotic spindle A physical cellular phenotype in which the meiotic spindle is normal (i.e. indistinguishable from wild type) with respect to structure, composition, location, and orientation. FYPO_relaxed.owl FYPO:0004569 biolink:NamedThing normal spindle during meiosis I A physical cellular phenotype in which the presence, distribution, or morphology of the meiotic spindle is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007747 biolink:NamedThing normal meiotic spindle length during prophase I A physical cellular phenotype in which the length of the meiotic spindle is normal (i.e. indistinguishable from wild type) during prophase I. FYPO_relaxed.owl FYPO:0004168 biolink:NamedThing normal viability in stationary phase during glucose starvation A cell population phenotype in which a normal proportion of cells in the population remains viable after entering stationary phase, under conditions of glucose starvation. FYPO_relaxed.owl FYPO:0004263 biolink:NamedThing normal viability in stationary phase during nitrogen limitation A cell population phenotype in which a normal proportion of cells in the population remains viable after entering stationary phase, under conditions of nitrogen limitation, such as in a medium that contains a low level of NH4Cl and no other nitrogen source. FYPO_relaxed.owl FYPO:0004175 biolink:NamedThing decreased mating efficiency in h- cells A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is lower than normal in cells of the h- mating type. FYPO_relaxed.owl FYPO:0006331 biolink:NamedThing decreased mating efficiency during stationary phase A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is lower than normal when the population in which the mating cells are found is in stationary phase. FYPO_relaxed.owl FYPO:0007962 biolink:NamedThing decreased mating efficiency during nitrogen starvation A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is lower than normal after nitrogen removal. FYPO_relaxed.owl FYPO:0008064 biolink:NamedThing decreased mating efficiency during phosphate starvation A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is lower than normal after phosphate removal. FYPO_relaxed.owl FYPO:0004177 biolink:NamedThing increased RNA level during nitrogen starvation in h- cells A cell phenotype in which the amount of RNA measured in a cell of the h- mating type when the cell is subject to nitrogen starvation is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004178 biolink:NamedThing increased RNA level during nitrogen starvation in h+ cells A cell phenotype in which the amount of RNA measured in a cell of the h+ mating type when the cell is subject to nitrogen starvation is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004458 biolink:NamedThing increased level of DNA replication gene mRNA during nitrogen starvation A cell phenotype in which the amount of one or more DNA replication RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells) when the cell is subject to nitrogen starvation. DNA replication RNAs are transcribed from genes whose products are involved in DNA replication. FYPO_relaxed.owl FYPO:0004459 biolink:NamedThing increased level of translation gene mRNA during nitrogen starvation A cell phenotype in which the amount of one or more translation RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells) when the cell is subject to nitrogen starvation. Translation RNAs are transcribed from genes whose products are involved in translation. FYPO_relaxed.owl FYPO:0004187 biolink:NamedThing abolished protein export from nucleus during cellular response to hydroxyurea A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein export from the nucleus does not occur during a cellular response to hydroxyurea. Export of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0006362 biolink:NamedThing decreased borderline-derived siRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which small interfering RNA transcripts derived from the lncRNA borderline are present at lower levels than normal. FYPO_relaxed.owl FYPO:0004208 biolink:NamedThing abnormal histone methyltransferase activity (H3-K4 specific) A molecular function phenotype in which the observed rate of H3-K4 specific histone methyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0004784 biolink:NamedThing decreased histone methyltransferase activity A molecular function phenotype in which the observed rate of a histone methyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0005846 biolink:NamedThing abnormal histone methyltransferase activity (H3-K9 specific) activity A molecular function phenotype in which the observed rate of H3-K9 specific histone methyltransferase activity is abnormal. FYPO_relaxed.owl FYPO:0005271 biolink:NamedThing abnormal microtubule plus-end directed mitotic chromosome migration A cellular process phenotype in which microtubule plus-end directed mitotic chromosome migration is abnormal. In microtubule plus-end directed mitotic chromosome migration, chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. FYPO_relaxed.owl FYPO:0005362 biolink:NamedThing abnormal mitotic metaphase chromosome recapture A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromosome recapture is abnormal during metaphase of mitosis. Chromosome recapture is the reattachment of chromosomes which have become detached from the spindle. FYPO_relaxed.owl FYPO:0006046 biolink:NamedThing uncentered mitotic chromosome congression A cellular process phenotype observed in the vegetative growth phase of the life cycle in which in which chromosomes do not align at the midpoint of the long axis of the mitotic spindle during metaphase chromosome congression. FYPO_relaxed.owl FYPO:0004216 biolink:NamedThing abolished histone H4-K20 monomethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which monomethylation of lysine at position 20 of histone H4 does not occur. FYPO_relaxed.owl FYPO:0008179 biolink:NamedThing decreased histone H4-K20 monomethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which monomethylation of lysine at position 20 of histone H4 is decreased. FYPO_relaxed.owl FYPO:0005611 biolink:NamedThing increased H4-K20 dimethylation at double-strand break site during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 20 of histone H4 occurs to a greater extent than normal in the region of a chromosome at which a DNA double-strand break has occurred. FYPO_relaxed.owl FYPO:0006753 biolink:NamedThing decreased histone H4-K20 dimethylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 20 of histone H4 in heterochromatin at subtelomeric regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0004221 biolink:NamedThing normal histone H4-K20 dimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 20 of histone H4 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004222 biolink:NamedThing normal histone H4-K20 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 20 of histone H4 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004226 biolink:NamedThing abolished nucleosome binding A molecular function phenotype in which nucleosome binding by a gene product (usually a protein) in a mutant does not occur. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006106 biolink:NamedThing abolished chromatin binding at centromere central core A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at the central core of the centromeric regions does not occur. FYPO_relaxed.owl FYPO:0008210 biolink:NamedThing abolished chromatin binding at promoter region A molecular function phenotype in which occurrence of chromatin binding by a gene product (usually a protein) at one or more promoter regions does not occur. FYPO_relaxed.owl FYPO:0004233 biolink:NamedThing decreased and delayed cell cycle arrest in mitotic G1 phase in response to nitrogen starvation A cellular process phenotype in which cell cycle arrest in response to nitrogen starvation occurs in G1 phase, but its occurrence is decreased and begins later than normal. FYPO_relaxed.owl FYPO:0004241 biolink:NamedThing decreased rate of DNA replication during cellular response to DNA damage A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of DNA replication is decreased during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0004244 biolink:NamedThing decreased protein kinase activity during mitotic S phase during cellular response to DNA damage A molecular function phenotype in which the observed rate of a protein kinase activity is decreased during S phase of the mitotic cell cycle during a cellular response to DNA damage. FYPO_relaxed.owl FYPO:0006233 biolink:NamedThing decreased protein localization to vacuolar membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuolar membrane is decreased. FYPO_relaxed.owl FYPO:0004372 biolink:NamedThing decreased response to mitotic G2 DNA damage checkpoint signaling A cellular process phenotype in which a mitotic cell cycle arrest that normally occurs in response to the mitotic G2 DNA damage checkpoint is decreased. The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage. In a mutant, the checkpoint may fail to arrest or delay cell cycle progression under appropriate conditions, or the incidence or duration of arrest or delay may differ from wild type under any specified set of conditions. FYPO_relaxed.owl FYPO:0004781 biolink:NamedThing delayed onset of mitotic G2 DNA damage checkpoint A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the mitotic G2 DNA damage checkpoint begins later than normal under conditions that normally trigger the checkpoint signaling and response. Normally, the mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage. FYPO_relaxed.owl FYPO:0004870 biolink:NamedThing decreased duration of mitotic G2 DNA damage checkpoint A cell cycle checkpoint phenotype in which the duration of mitotic cell cycle arrest or delay due to regulation by the mitotic G2 DNA damage checkpoint is shorter than normal. The DNA replication checkpoint normally prevents the initiation of mitosis until DNA replication is complete. FYPO_relaxed.owl FYPO:0005953 biolink:NamedThing increased duration of mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by the mitotic G2 DNA damage checkpoint is greater than in wild type during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0004261 biolink:NamedThing decreased protein phosphorylation during mitotic G2 phase during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during G2 phase of the mitotic cell cycle and during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0004554 biolink:NamedThing decreased protein phosphorylation during mitotic S phase during cellular response to ionizing radiation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during S phase of the mitotic cell cycle and during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0004268 biolink:NamedThing decreased septum disassembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of septum disassembly is decreased. FYPO_relaxed.owl FYPO:0004270 biolink:NamedThing decreased cell septum edging catabolic process A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dissolution of the cell septum edging material is decreased. FYPO_relaxed.owl FYPO:0004273 biolink:NamedThing decreased ascospore release from ascus A cellular process phenotype in which the occurrence of ascospore release from an ascus is decreased. FYPO_relaxed.owl FYPO:0004534 biolink:NamedThing premature ascospore release from ascus A cellular process phenotype in which the occurrence of ascospore release from an ascus begins earlier than normal. FYPO_relaxed.owl FYPO:0004286 biolink:NamedThing normal double-strand break repair via nonhomologous end joining A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of double-strand break repair via nonhomologous end joining (NHEJ) is normal (i.e. indistinguishable from wild type). NHEJ is the repair of double-strand breaks in DNA in which the two broken ends are rejoined with little or no sequence complementarity. FYPO_relaxed.owl FYPO:0005398 biolink:NamedThing normal frequency of double-strand break repair via homologous recombination A cellular process phenotype in which the frequency of occurrence of double-strand break repair via homologous recombination is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004291 biolink:NamedThing decreased GT microsatellite DNA binding A molecular function phenotype in which occurrence of DNA binding at GT dinucleotide microsatellite repeat regions by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0004306 biolink:NamedThing decreased CTD phosphatase activity A molecular function phenotype in which the observed rate of CTD phosphatase activity is decreased. FYPO_relaxed.owl FYPO:0004307 biolink:NamedThing long mitotic spindle during metaphase A spindle phenotype in which the mitotic spindle is longer than normal during metaphase. FYPO_relaxed.owl FYPO:0004438 biolink:NamedThing long mitotic spindle during anaphase A spindle phenotype in which the mitotic spindle is longer than normal during anaphase. FYPO_relaxed.owl FYPO:0004439 biolink:NamedThing long curved mitotic spindle during anaphase A spindle phenotype in which the mitotic spindle is curved (i.e. follows a smooth bend rather than a straight line) and longer than normal during anaphase. FYPO_relaxed.owl FYPO:0004311 biolink:NamedThing abnormal protein localization to CENP-A containing chromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to CENP-A containing chromatin is abnormal. FYPO_relaxed.owl FYPO:0005898 biolink:NamedThing increased protein localization to centromeric chromatin during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is increased during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005888 biolink:NamedThing decreased protein localization to centromeric chromatin, with protein mislocalized to nucleoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is decreased, and some of the protein is present in the nucleoplasm instead. FYPO_relaxed.owl FYPO:0005895 biolink:NamedThing decreased protein localization to centromeric chromatin during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is decreased during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006600 biolink:NamedThing decreased protein localization to centromeric chromatin during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is decreased during metaphase of mitosis. FYPO_relaxed.owl FYPO:0004314 biolink:NamedThing normal protein localization to CENP-A containing chromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the CENP-A containing chromatin is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006601 biolink:NamedThing normal protein localization to centromeric chromatin during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to centromeric chromatin is normal (i.e. indistinguishable from wild type during metaphase of mitosis. FYPO_relaxed.owl FYPO:0004324 biolink:NamedThing increased histone H4-K16 acetylation at centromere central core during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 in at the centromere central core occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005535 biolink:NamedThing increased histone H4-K16 acetylation at telomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 in telomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006752 biolink:NamedThing increased histone H4-K16 acetylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 in heterochromatin at subtelomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007635 biolink:NamedThing increased histone H4-K16 acetylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 16 of histone H4 in regions containing protein coding genes occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0008174 biolink:NamedThing increased histone H4-K16 acetylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the acetylation of lysine at position 16 of histone H4 in silent mating-type cassettes occurs to a higher extent than normal. FYPO_relaxed.owl FYPO:0004329 biolink:NamedThing normal mitotic rDNA separation A cellular process phenotype in which mitotic sister chromatid separation is normal (i.e. indistinguishable from wild type) in regions containing ribosomal DNA (rDNA). Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis. FYPO_relaxed.owl FYPO:0004330 biolink:NamedThing normal mitotic telomeric DNA separation A cellular process phenotype in which mitotic sister chromatid separation is normal (i.e. indistinguishable from wild type) at telomeres. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis. FYPO_relaxed.owl FYPO:0004333 biolink:NamedThing increased protein phosphorylation during cellular response to hydrogen peroxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0004335 biolink:NamedThing abolished protein-protein interaction during cellular response to hydrogen peroxide A molecular function phenotype in which the binding of one protein to another does not occur during a cellular response to hydrogen peroxide. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0004547 biolink:NamedThing increased protein localization to mitochondrion A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion is increased. FYPO_relaxed.owl FYPO:0007038 biolink:NamedThing decreased protein localization to mitochondrion A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion is decreased. FYPO_relaxed.owl FYPO:0007600 biolink:NamedThing decreased protein localization to mitochondrial outer membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrial outer membrane is decreased. FYPO_relaxed.owl FYPO:0004341 biolink:NamedThing delayed onset of mitochondrial fission during cellular response to hydrogen peroxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission, the division of a mitochondrion into two or more separate compartments, begins later than normal during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0007196 biolink:NamedThing decreased mitochondrial fission A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission, the division of a mitochondrion into two or more separate compartments, occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007197 biolink:NamedThing increased mitochondrial fission A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial fission, the division of a mitochondrion into two or more separate compartments, occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0004358 biolink:NamedThing increased protein phosphatase activity during mitosis A molecular function phenotype in which the observed rate of a protein phosphatase activity is increased during mitosis. FYPO_relaxed.owl FYPO:0004361 biolink:NamedThing meiotic cell cycle entry and sporulation in haploid during nitrogen starvation A cellular process phenotype in which haploid cells undergo meiotic nuclear division and attempt to sporulate when the cells are subject to nitrogen starvation. Haploid meiosis often results in the formation of a structure that resembles an azygotic ascus. Spores produced from a haploid cell have poor viability and appear to contain only 1/2C DNA on average. FYPO_relaxed.owl FYPO:0004362 biolink:NamedThing increased protein localization to old growing cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to an old growing cell tip is increased. FYPO_relaxed.owl FYPO:0004871 biolink:NamedThing abnormal 2-oxoglutarate dioxygenase activity A molecular function phenotype in which the observed rate of a 2-oxoglutarate-dependent dioxygenase activity is abnormal. FYPO_relaxed.owl FYPO:0005638 biolink:NamedThing merotelic kinetochore attachment during meiosis I A cellular process phenotype in which the attachment of spindle microtubules to the kinetochore during the first meiotic nuclear division results in the connection of a single kinetochore to both spindle poles. FYPO_relaxed.owl FYPO:0004384 biolink:NamedThing normal single-stranded DNA binding A molecular function phenotype in which occurrence of single-stranded DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005298 biolink:NamedThing normal oxidized DNA binding A molecular function phenotype in which occurrence of oxidized DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006088 biolink:NamedThing normal DNA binding during cellular response to DNA damage A molecular function phenotype in which occurrence of DNA binding by a gene product is normal (i.e. indistinguishable from wild type) during a cellular response to DNA damage. The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006653 biolink:NamedThing normal flap-structured DNA binding A molecular function phenotype in which occurrence of flap-structured DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006654 biolink:NamedThing normal G-quadruplex DNA binding A molecular function phenotype in which occurrence of G-quadruplex DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0004385 biolink:NamedThing decreased single-stranded DNA binding A molecular function phenotype in which occurrence of single-stranded DNA binding by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006677 biolink:NamedThing decreased DNA binding at double-strand break A molecular function phenotype in which occurrence of DNA binding at double-strand break sites by a gene product is decreased, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0004386 biolink:NamedThing abolished single-stranded DNA binding A molecular function phenotype in which single-stranded DNA binding by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006153 biolink:NamedThing abolished DNA binding at STREP motif A molecular function phenotype in which DNA binding at a STREP motif by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0004389 biolink:NamedThing increased level of amino acid catabolism gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more amino acid catabolism RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Amino acid catabolism RNAs are transcribed from genes whose products are involved in amino acid catabolism. FYPO_relaxed.owl FYPO:0004489 biolink:NamedThing increased level of amino acid biosynthesis gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more amino acid biosynthesis RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Amino acid biosynthesis RNAs are transcribed from genes whose products are involved in amino acid biosynthetic processes. FYPO_relaxed.owl FYPO:0004390 biolink:NamedThing increased level of arginine catabolism gene mRNA during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more arginine catabolism RNAs measured in a cell is higher than normal (i.e. higher than observed in wild-type cells). Arginine catabolism RNAs are transcribed from genes whose products are involved in arginine catabolism. FYPO_relaxed.owl FYPO:0004395 biolink:NamedThing short bipolar mitotic spindle during metaphase A spindle phenotype in which the mitotic spindle is shorter than normal during metaphase. FYPO_relaxed.owl FYPO:0007304 biolink:NamedThing short bipolar mitotic spindle during anaphase A spindle phenotype in which the mitotic spindle is shorter than normal during anaphase. FYPO_relaxed.owl FYPO:0009113 biolink:NamedThing abolished protein localization to mitotic spindle polar microtubules during anaphase B A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle polar microtubules during anaphase B does not occur. FYPO_relaxed.owl FYPO:0004427 biolink:NamedThing delayed onset of ribosomal S6 protein dephosphorylation during cellular response to nitrogen starvation A cellular process phenotype in which the dephosphorylation of the ribosomal small subunit protein S6 begins later than normal when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0004437 biolink:NamedThing normal mitotic recombination frequency A cellular process phenotype in which the frequency of occurrence of mitotic recombination is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004440 biolink:NamedThing normal cytosolic calcium level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in the cytosol is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004441 biolink:NamedThing decreased cytosolic calcium level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of calcium ion measured in the cytosol is lower than normal. FYPO_relaxed.owl FYPO:0006827 biolink:NamedThing decreased cytosolic zinc level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of zinc ion measured in the cytosol is lower than normal. FYPO_relaxed.owl FYPO:0004442 biolink:NamedThing decreased protein localization to prospore membrane A cell phenotype in which the localization of a protein to the prospore membrane is decreased. FYPO_relaxed.owl FYPO:0004932 biolink:NamedThing increased duration of protein localization to prospore membrane A cell phenotype in which one or more proteins is localized to the prospore membrane for a longer time than normal. FYPO_relaxed.owl FYPO:0004449 biolink:NamedThing decreased protein phosphorylation during mitotic metaphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during metaphase of mitosis. FYPO_relaxed.owl FYPO:0006766 biolink:NamedThing decreased protein phosphorylation in absence of meiotic DNA replication checkpoint arrest A cellular process phenotype in which the phosphorylation of one or more specific proteins occurs to a lower extent than normal during the meiotic cell cycle, in cells that have not arrested the meiotic cell cycle under conditions that normally trigger meiotic DNA replication checkpoint signaling and response. FYPO_relaxed.owl FYPO:0004466 biolink:NamedThing increased number of Rad52 foci during cellular response to camptothecin A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal during a cellular response to camptothecin. FYPO_relaxed.owl FYPO:0004819 biolink:NamedThing increased number of Rad52 foci at rDNA replication origins A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of DNA replication origins in ribosomal DNA at which the protein Rad52 (also called Rad22) accumulates is greater than normal. FYPO_relaxed.owl FYPO:0004820 biolink:NamedThing increased number of Rad52 foci at rDNA replication pause sites A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of DNA replication pause sites in ribosomal DNA at which the protein Rad52 (also called Rad22) accumulates is greater than normal. FYPO_relaxed.owl FYPO:0004846 biolink:NamedThing increased number of Rad52 foci at telomeres A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of DNA replication pause sites in telomeric regions at which the protein Rad52 (also called Rad22) accumulates is greater than normal. FYPO_relaxed.owl FYPO:0005296 biolink:NamedThing increased number of Rad52 foci during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005777 biolink:NamedThing increased number of Rad52 foci during cellular response to acetaldehyde A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal during a cellular response to acetaldehyde. FYPO_relaxed.owl FYPO:0006618 biolink:NamedThing increased number of Rad52 foci during cellular response to bleomycin A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal during a cellular response to bleomycin. FYPO_relaxed.owl FYPO:0006678 biolink:NamedThing increased number of Rad52 foci during cellular response to chromium A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal during a cellular response to chromium ions. FYPO_relaxed.owl FYPO:0007550 biolink:NamedThing increased number of Rad52 foci during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is greater than normal during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0004470 biolink:NamedThing decreased protein localization to actomyosin contractile ring during mitotic anaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is decreased during anaphase of mitosis. FYPO_relaxed.owl FYPO:0006058 biolink:NamedThing abnormal vacuole fusion during sporulation A cellular process phenotype in which vacuole fusion, the merging of two vacuole membranes to form a single vacuole, is abnormal during sporulation. FYPO_relaxed.owl FYPO:0004483 biolink:NamedThing abnormal vacuole fusion during cellular hypotonic response A cellular process phenotype observed in the vegetative growth phase of the life cycle in which vacuole fusion is abnormal during a cellular response to a hypotonic environment. FYPO_relaxed.owl FYPO:0004495 biolink:NamedThing inviable branched, swollen, elongated, multiseptate vegetative cell A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell is inviable, branched, has more than one septum, and has a larger volume and is longer, than normal. In a swollen cell, both length and diameter may be greater than normal, although the cell is only considered elongated if the length:diameter ratio is also greater than normal. FYPO_relaxed.owl FYPO:0004500 biolink:NamedThing decreased DNA polymerase processivity factor activity A molecular function phenotype in which the rate or occurrence of DNA polymerase processivity factor activity is decreased. FYPO_relaxed.owl FYPO:0005205 biolink:NamedThing increased DNA polymerase processivity factor activity A molecular function phenotype in which the rate or occurrence of DNA polymerase processivity factor activity is increased. FYPO_relaxed.owl FYPO:0004506 biolink:NamedThing abnormal nucleolar chromatin organization resulting in peripheral chromatin distribution A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleolar chromatin organization is abnormal, such that nucleolar chromatin is distributed in a ring-shaped structure around the nuclear periphery rather than in a crescent-shaped structure on one side of the nucleus. FYPO_relaxed.owl FYPO:0004508 biolink:NamedThing abolished rDNA separation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation does not occur at the rDNA repeat regions. The remainder of the sister chromatids may or may not separate. FYPO_relaxed.owl FYPO:0004510 biolink:NamedThing abnormal spindle assembly during meiosis II A cellular process phenotype in which assembly of the meiotic spindle is abnormal during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0007745 biolink:NamedThing abnormal spindle assembly during meiosis I A cellular process phenotype in which assembly of the meiotic spindle is abnormal during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007848 biolink:NamedThing meiotic spindle self-assembly A cellular process phenotype in which microtubules self-assemble into a spindle without the participation of the spindle pole body (SPB) during one or both meiotic nuclear divisions. This phenotype is observed in the absence of both bouquet formation and meiotic SPB insertion into the nuclear envelope. FYPO_relaxed.owl FYPO:0004511 biolink:NamedThing long curved interphase microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are longer than normal and are curved, i.e. follow a smooth bend rather than a straight line, during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004611 biolink:NamedThing long interphase microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are longer than normal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004612 biolink:NamedThing long astral microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form astral microtubules that are longer than normal. FYPO_relaxed.owl FYPO:0004865 biolink:NamedThing long astral microtubules during mitotic anaphase A A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form astral microtubules that are longer than normal during anaphase A. Anaphase A is the stage of mitosis in which the kinetochore microtubules shorten as chromosomes move toward the spindle poles. FYPO_relaxed.owl FYPO:0005427 biolink:NamedThing elongated J-shaped vegetative cell with curved interphase microtubules A cell morphology phenotype in which a vegetatively growing cell is elongated, is curved along the long axis to form a "J" shape, and contains cytoplasmic microtubules that curve to follow the long axis of the cell. In a curved cell, the long axis follows a smooth bend rather than a straight line. In a J-shaped cell, the curve is centered away from the midpoint of the long axis of the cell. FYPO_relaxed.owl FYPO:0005879 biolink:NamedThing C-shaped interphase microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form cytoplasmic microtubules that are curved to form a "C" shape, i.e. they follow a smooth bend rather than a straight line, with the curve centered at or near the midpoint of the microtubule, during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004518 biolink:NamedThing inviable after spore germination, multiple cell divisions, branched, curved, elongated cell A phenotype in which a spore germinates to produce a cell that is elongated and branched (and septated) and is curved along the long axis, and undergoes two or more rounds of cell division and then dies. FYPO_relaxed.owl FYPO:0004520 biolink:NamedThing decreased DNA-directed DNA polymerase processivity A molecular function phenotype in which the observed processivity of a DNA-directed DNA polymerase activity is lower than normal. Processivity refers to the number of nucleotides incorporated into a nascent DNA strand per polymerase-DNA binding event. FYPO_relaxed.owl FYPO:0004522 biolink:NamedThing inviable after spore germination, single or double cell division, branched, curved, elongated cell A phenotype in which a spore germinates to produce a cell that is elongated and branched (and septated) and is curved along the long axis, and undergoes one or two rounds of cell division and then dies. FYPO_relaxed.owl FYPO:0004704 biolink:NamedThing interphase microtubules present in increased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more cytoplasmic microtubules than normal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004541 biolink:NamedThing increased chromatin silencing at centromere inner repeat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere inner repeat regions is increased. FYPO_relaxed.owl FYPO:0004542 biolink:NamedThing increased chromatin silencing at subtelomere A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at subtelomeric regions is increased. FYPO_relaxed.owl FYPO:0004549 biolink:NamedThing normal S-phase DNA damage checkpoint during cellular response to UV A cell cycle checkpoint phenotype in which the S-phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is normal (i.e. indistinguishable from wild type) when the cell is exposed to ultraviolet light. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. FYPO_relaxed.owl FYPO:0005299 biolink:NamedThing normal mitotic G2 DNA damage checkpoint during cellular response to UV A cell cycle checkpoint phenotype in which the mitotic G2 DNA damage checkpoint is normal (i.e. indistinguishable from wild type) when the cell is exposed to ultraviolet light. The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage. FYPO_relaxed.owl FYPO:0004601 biolink:NamedThing normal S-phase DNA damage checkpoint during cellular response to hydroxyurea A cell cycle checkpoint phenotype in which the S-phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is normal (i.e. indistinguishable from wild type) when the cell is exposed to hydroxyurea. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. FYPO_relaxed.owl FYPO:0006605 biolink:NamedThing normal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate A cell cycle checkpoint phenotype in which the S-phase DNA damage checkpoint (also known as the intra-S phase DNA damage checkpoint) is normal (i.e. indistinguishable from wild type) when the cell is exposed to methyl methanesulfonate. The S phase DNA damage checkpoint slows progression through S phase in response to DNA damage. FYPO_relaxed.owl FYPO:0004571 biolink:NamedThing increased RNA level during cellular response to hydrogen peroxide A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular response to hydrogen peroxide is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0004572 biolink:NamedThing decreased exocytosis during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which exocytosis occurs to a lower extent than normal. Exocytosis is the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. A phenotype may affect exocytosis of all cargoes, or of specific cargo such as a particular protein. FYPO_relaxed.owl FYPO:0006883 biolink:NamedThing decreased exocytosis at cell division site A cellular process phenotype observed in the vegetative growth phase of the life cycle in which exocytosis occurs to a lower extent than normal at the cell division site. FYPO_relaxed.owl FYPO:0004576 biolink:NamedThing decreased histone H3-K9 acetylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in subtelomeric regions occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007217 biolink:NamedThing decreased histone H3-K9 acetylation at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in regions containing protein-coding genes occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006316 biolink:NamedThing spindle pole bodies present in increased numbers during meiosis II A physical cellular phenotype in which cells contain more spindle pole bodies (SPBs) than normal during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0004590 biolink:NamedThing abnormal gamma-tubulin complex localization to mitotic spindle pole body following normal mitosis A cellular process phenotype in which localization of the gamma-tubulin complex to the spindle pole body takes place abnormally after the cell has undergone a normal mitotic nuclear division and passed through the subsequent mitotic interphase. FYPO_relaxed.owl FYPO:0004591 biolink:NamedThing monopolar mitotic spindle following normal mitosis A physical cellular phenotype in which the mitotic spindle forms with microtubules emanating from only one pole after the cell has undergone a normal mitotic nuclear division and passed through the subsequent mitotic interphase. FYPO_relaxed.owl FYPO:0005029 biolink:NamedThing decreased gamma-tubulin complex localization to mitotic spindle pole body A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of the gamma-tubulin complex to the spindle pole body is decreased. FYPO_relaxed.owl FYPO:0005381 biolink:NamedThing asymmetric gamma-tubulin complex localization to single mitotic spindle pole body A cellular process phenotype in which the gamma-tubulin complex is localized to only one spindle pole body instead of both. FYPO_relaxed.owl FYPO:0009114 biolink:NamedThing transient monopolar mitotic spindle A physical cellular phenotype in which the mitotic spindle remains monopolar when formed, with microtubules emanating from only one pole, for longer than wild-type, but eventually reaches bipolarity. FYPO_relaxed.owl FYPO:0004596 biolink:NamedThing abnormal negative regulation of DNA replication initiation during mitotic G2 phase resulting in complete rereplication A regulation phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of the initiation of DNA-dependent DNA replication is abnormal, with replication reinitiating during G2 phase of the mitotic cell cycle and resulting in one or more rounds of rereplication of the entire genome. FYPO_relaxed.owl FYPO:0006575 biolink:NamedThing abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication, with otherwise normal S phase A regulation phenotype observed in the vegetative growth phase of the life cycle in which abnormal negative regulation of the initiation of mitotic DNA replication results in one or more rounds of rereplication of the entire genome, but takes place during S phases that appear nearly normal apart from occurring without intervening mitoses. Origin usage is normal, rounds of DNA synthesis are correlated with G1/S phase gene expression and cell mass increase, and the genome is replicated evenly. FYPO_relaxed.owl FYPO:0006576 biolink:NamedThing abnormal negative regulation of mitotic DNA replication initiation resulting in complete rereplication, with abnormal S phase A regulation phenotype observed in the vegetative growth phase of the life cycle in which abnormal negative regulation of the initiation of mitotic DNA replication results in one or more rounds of rereplication of the entire genome, and other features of S phase are abnormal. Rounds of replication are not correlated with G1/S phase gene expression, and origin usage is altered. FYPO_relaxed.owl FYPO:0007858 biolink:NamedThing mitotic DNA re-replication in absence of mitotic spindle A regulation phenotype observed in the vegetative growth phase of the life cycle in which a cell undergoes one or more rounds of rereplication of the entire genome without forming a mitotic spindle or undergoing cytokinesis. FYPO_relaxed.owl FYPO:0004608 biolink:NamedThing abnormal spindle pole body morphology during meiosis II A physical cellular phenotype in which the size, shape, or structure of the spindle pole body is abnormal during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0006022 biolink:NamedThing abnormal spindle pole body morphology during meiosis I A physical cellular phenotype in which the size, shape, or structure of the spindle pole body is abnormal during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006365 biolink:NamedThing meiotic spindle pole body detached from nucleus A cell phenotype in which the meiotic spindle pole body (SPB) dissociates from the nucleus. Normally the SPB is embedded in the nuclear envelope. FYPO_relaxed.owl FYPO:0004615 biolink:NamedThing increased rate of mitotic interphase microtubule polymerization A microtubule cytoskeleton organization phenotype observed during interphase of the mitotic cell cycle in which cytoplasmic microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a cytoplasmic microtubule, occurs at a higher rate, or speed, than normal. FYPO_relaxed.owl FYPO:0007970 biolink:NamedThing increased rate of microtuble polymerization during vegetative growth A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule occurs at a higher rate, or speed, than normal. FYPO_relaxed.owl FYPO:0007971 biolink:NamedThing increased rate of interpolar microtubule polymerization during mitotic anaphase B A microtubule cytoskeleton organization phenotype observed during mitotic anaphase B in which interpolar microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule occurs at a higher rate, or speed, than normal. FYPO_relaxed.owl FYPO:0004616 biolink:NamedThing abolished cytoplasmic microtubule depolymerization at plus end at cell tip A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubule depolymerization, i.e. the removal of tubulin dimers from a cytoplasmic microtubule, does not occur at the plus end of the microtubule at the cell tip. Normally, rapid depolymerization takes place when the growing plus end of the microtubule reaches the cell tip. FYPO_relaxed.owl FYPO:0005682 biolink:NamedThing decreased microtubule depolymerization during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule depolymerization, i.e. the removal of tubulin dimers, occurs to a lesser extent than normal. FYPO_relaxed.owl FYPO:0006105 biolink:NamedThing increased microtubule depolymerization at cell side A cell phenotype observed in the vegetative growth phase of the life cycle in which the removal of tubulin dimers from a microtubule occurs to a greater extent than normal in the lateral part of the cell. FYPO_relaxed.owl FYPO:0007182 biolink:NamedThing decreased cytoplasmic microtubule depolymerization at plus end at cell tip A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubule depolymerization, i.e. the removal of tubulin dimers from a cytoplasmic microtubule, occurs to a lesser extent than normal at the plus end of the microtubule at the cell tip. Normally, rapid depolymerization takes place when the growing plus end of the microtubule reaches the cell tip. FYPO_relaxed.owl FYPO:0007706 biolink:NamedThing decreased microtubule depolymerization at cell side A cell phenotype observed in the vegetative growth phase of the life cycle in which the removal of tubulin dimers from a microtubule occurs to a lower extent than normal in the lateral part of the cell. FYPO_relaxed.owl FYPO:0004618 biolink:NamedThing astral microtubules absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable astral microtubules. FYPO_relaxed.owl FYPO:0004702 biolink:NamedThing cytoplasmic microtubules absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable cytoplasmic microtubules. FYPO_relaxed.owl FYPO:0004619 biolink:NamedThing cytoplasmic microtubules nucleated from eMTOC absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable cytoplasmic microtubules nucleated from the equatorial microtubule organizing center (eMTOC). FYPO_relaxed.owl FYPO:0006102 biolink:NamedThing interphase microtubules absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable cytoplasmic microtubules during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004881 biolink:NamedThing increased duration of mitotic spindle disassembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle disassembly lasts for a longer time than normal. FYPO_relaxed.owl FYPO:0006559 biolink:NamedThing delayed onset of mitotic spindle disassembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle disassembly begins later than normal. FYPO_relaxed.owl FYPO:0007985 biolink:NamedThing early eMTOC assembly A cellular process phenotype in which equatorial microtubule organizing center (eMTOC) assembly occurs earlier than normal. eMTOC assembly is the aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center. FYPO_relaxed.owl FYPO:0004631 biolink:NamedThing decreased protein level during meiotic anaphase I A cell phenotype in which the amount of protein measured in a cell during anaphase of the first meiotic nuclear division is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004938 biolink:NamedThing decreased protein level during meiosis I A cell phenotype in which the amount of protein measured in a cell during the first meiotic nuclear division is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004632 biolink:NamedThing decreased protein level during meiosis II A cell phenotype in which the amount of protein measured in a cell during the second meiotic nuclear division is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0004650 biolink:NamedThing decreased mitotic spindle microtubule depolymerization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule in the mitotic spindle, occurs to a lesser extent than normal. FYPO_relaxed.owl FYPO:0004652 biolink:NamedThing normal actomyosin contractile ring morphology A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, and structure of the actomyosin contractile ring is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004741 biolink:NamedThing normal F-actin level in actomyosin contractile ring during anaphase B A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount of filamentous actin (F-actin) in the actomyosin contractile ring is normal (i.e. indistinguishable from wild type) during mitotic anaphase B. FYPO_relaxed.owl FYPO:0006352 biolink:NamedThing normal F-actin level in actomyosin contractile ring during early mitosis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the amount of filamentous actin (F-actin) in the actomyosin contractile ring is normal (i.e. indistinguishable from wild type) during early mitosis (before anaphase). FYPO_relaxed.owl FYPO:0005055 biolink:NamedThing binucleate multiseptate cell, septa grouped A cell morphology phenotype observed in the vegetative growth phase of the life cycle in which a cell has two and more than one septum, and the septa are grouped together between the two compartments, one or more of which may contain multiple nuclei. FYPO_relaxed.owl FYPO:0004665 biolink:NamedThing linear elements absent from cell A physical cellular phenotype in which linear elements are absent from the cell. FYPO_relaxed.owl FYPO:0004678 biolink:NamedThing increased polyadenylated 25S rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature, polyadenylated 25S rRNA measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0008100 biolink:NamedThing increased polyadenylated 5S rRNA level during cellular response to phosphate starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of mature, polyadenylated 5S rRNA measured in a cell is higher than normal during phosphate starvation. FYPO_relaxed.owl FYPO:0004681 biolink:NamedThing decreased polyadenylated 5.8S rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the mature polyadenylated 5.8S rRNA measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0007293 biolink:NamedThing lysed spherical vegetative cell A cell phenotype in which a spherical vegetative cell lyses, i.e. the plasma membrane ruptures and cytoplasm is lost. FYPO_relaxed.owl FYPO:0005794 biolink:NamedThing bent cell during G0 to G1 transition A cell morphology phenotype in which a cell is bent along the long axis when the cell undergoes transition from G0 phase to G1. In a bent cell, the long axis has one or more angles, rather than following a straight line. FYPO_relaxed.owl FYPO:0004715 biolink:NamedThing large vacuoles present in decreased numbers during salt stress A cell phenotype observed in the vegetative growth phase of the life cycle in which a cell contains fewer, but larger, vacuoles than normal when the cell is subject to salt stress. FYPO_relaxed.owl FYPO:0008192 biolink:NamedThing increased protein localization to pericentric heterochromatin during meiotic prophase I A cell phenotype in which the localization of a protein to pericentric heterochromatin is increased during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0004723 biolink:NamedThing transiently misoriented mitotic spindle A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle is assembled in an incorrect orientation. Spindle orientation is later corrected so that the spindle is parallel to the long axis of the cell. FYPO_relaxed.owl FYPO:0004728 biolink:NamedThing cytoplasmic microtubule formation from nuclear microtubules following nuclear envelope breakthrough A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubules are formed by the extension of existing nuclear microtubules through a puncture in the nuclear envelope. Normally, cytoplasmic microtubules are nucleated from microtubule organizing centers in the cytoplasm. FYPO_relaxed.owl FYPO:0004729 biolink:NamedThing cytoplasmic microtubule formation from nuclear microtubules following spindle microtubule fragmentation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubules are formed by the extension of existing nuclear microtubules arising from fragmentation of the mitotic spindle. Normally, cytoplasmic microtubules are nucleated from microtubule organizing centers in the cytoplasm. FYPO_relaxed.owl FYPO:0004731 biolink:NamedThing normal protein localization to interphase microtubule plus-end A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plus-end of a cytoplasmic microtubule is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007452 biolink:NamedThing normal protein localization to microtubule plus-end A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plus ends end of microtubules is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004735 biolink:NamedThing abolished protein localization to medial cortical node, with protein mislocalized to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is abolished, and the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0007139 biolink:NamedThing abolished protein localization to medial cortical node during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is abolished during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004742 biolink:NamedThing normal chromatin silencing at centromere outer repeat A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the outer repeat region of the centromere is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006995 biolink:NamedThing normal chromatin silencing at centromere inner repeat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere inner repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004743 biolink:NamedThing normal histone H3-K9 dimethylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008199 biolink:NamedThing normal histone H3-K9 trimethylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the trimethylation of lysine at position 9 of histone H3 at the centromere outer repeat is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004745 biolink:NamedThing abolished histone H3-K9 dimethylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions does not occur. FYPO_relaxed.owl FYPO:0005843 biolink:NamedThing abolished histone H3-K9 trimethylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 9 of histone H3 in centromere outer repeat regions does not occur. FYPO_relaxed.owl FYPO:0005554 biolink:NamedThing abolished histone H3-K9 dimethylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in centromere inner repeat regions does not occur. FYPO_relaxed.owl FYPO:0006112 biolink:NamedThing abolished histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 in silent mating-type cassettes does not occur. FYPO_relaxed.owl FYPO:0007224 biolink:NamedThing decreased heterochromatin assembly at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin assembly is decreased in centromere outer repeat regions. Heterochromatin assembly is the assembly of chromatin into a compact and highly condensed form that is often, but not always, transcriptionally silent. FYPO_relaxed.owl FYPO:0005913 biolink:NamedThing abnormal chromatin remodeling during meiosis I A cellular process phenotype in which chromatin remodeling that occurs as part of meiosis I is abnormal. FYPO_relaxed.owl FYPO:0006357 biolink:NamedThing decreased chromatin remodeling during glucose starvation A cellular process phenotype in which chromatin remodeling, i.e. any dynamic structural change to chromatin, occurs to a lower extent than normal when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0004748 biolink:NamedThing decreased histone exchange at pericentric heterochromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a lower extent than normal in regions of pericentric heterochromatin. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. FYPO_relaxed.owl FYPO:0004759 biolink:NamedThing abnormal negative regulation of premeiotic DNA replication initiation resulting in complete rereplication A regulation phenotype in which negative regulation of the initiation of premeiotic DNA replication is abnormal, resulting in one or more rounds of rereplication of the entire genome. FYPO_relaxed.owl FYPO:0004855 biolink:NamedThing abnormal negative regulation of premeiotic DNA replication initiation resulting in partial rereplication A regulation phenotype in which negative regulation of the initiation of premeiotic DNA replication is abnormal, resulting in rereplication of part of the genome. FYPO_relaxed.owl FYPO:0004760 biolink:NamedThing abnormal sporulation resulting in formation of azygotic ascus with more than four spores A sporulation phenotype in which azygotic asci that contain more than four, and up to eight, spores form following conjugation, diploid growth, and subsequent azygotic sporulation. Azygotic ascus formation occurs when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell. FYPO_relaxed.owl FYPO:0004761 biolink:NamedThing increased histone exchange at pericentric heterochromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a greater extent than normal in regions of pericentric heterochromatin. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. FYPO_relaxed.owl FYPO:0004764 biolink:NamedThing normal protein localization to meiotic spindle pole body during meiosis I A cell phenotype in which the localization of a protein to the meiotic spindle pole body is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006055 biolink:NamedThing normal protein localization to meiotic spindle pole body during meiosis II A cell phenotype in which the localization of a protein to the meiotic spindle pole body is normal (i.e. indistinguishable from wild type) during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0004766 biolink:NamedThing abolished cytoplasmic interphase microtubule nucleation A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules from one or both of the normal nucleation sites does not occur during interphase of the mitotic cell cycle. Normally, microtubules are nucleated from interphase microtubule organizing centers (iMTOCs) and from the cytoplasmic face of the spindle pole body (SPB). FYPO_relaxed.owl FYPO:0005698 biolink:NamedThing abolished microtubule nucleation from eMTOC A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of microtubules from the equatorial microtubule organizing center does not occur. FYPO_relaxed.owl FYPO:0005553 biolink:NamedThing normal single-stranded telomeric DNA binding A molecular function phenotype in which occurrence of single-stranded telomeric DNA binding by a gene product is normal (i.e. indistinguishable from wild type). The relevant gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0004791 biolink:NamedThing increased telomere-nuclear envelope distance during mitotic G2 phase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between one or more telomeres and the nuclear envelope is greater than normal during G2 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004792 biolink:NamedThing decreased telomere-nuclear envelope distance during mitotic G2 phase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between one or more telomeres and the nuclear envelope is smaller than normal during G2 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004793 biolink:NamedThing decreased telomere-nuclear envelope distance during mitotic M phase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between one or more telomeres and the nuclear envelope is smaller than normal during mitosis. FYPO_relaxed.owl FYPO:0004890 biolink:NamedThing increased telomere-nuclear envelope distance during mitosis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the distance between one or more telomeres and the nuclear envelope is greater than normal during mitosis. FYPO_relaxed.owl FYPO:0004797 biolink:NamedThing normal azygotic meiosis I A cellular process phenotype in which the first meiotic nuclear division is normal (i.e. indistinguishable from wild type) during a cycle of azygotic meiosis and sporulation. Azygotic meiosis and sporulation occur when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell. FYPO_relaxed.owl FYPO:0004995 biolink:NamedThing normal onset of meiosis I A cellular process phenotype in which the first meiotic nuclear division begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events. FYPO_relaxed.owl FYPO:0005383 biolink:NamedThing normal duration of meiosis I A cellular process phenotype in which the duration of the first meiotic nuclear division is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004798 biolink:NamedThing abolished azygotic meiosis II A cellular process phenotype in which the second meiotic nuclear division does not occur during a cycle of azygotic meiosis and sporulation. Azygotic meiosis and sporulation occur when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell. FYPO_relaxed.owl FYPO:0004799 biolink:NamedThing abolished zygotic meiosis II A cellular process phenotype in which the second meiotic nuclear division does not occur during a cycle of zygotic meiosis and sporulation. Zygotic meiosis and sporulation take place under conditions of continuous nitrogen starvation, in which haploid cells of the opposite mating types conjugate to form diploid zygotes that proceed immediately to undergo meiosis and sporulation. FYPO_relaxed.owl FYPO:0004800 biolink:NamedThing abolished premeiotic DNA replication during azygotic meiotic cell cycle A cellular process phenotype in which premeiotic DNA replication does not occur during a cycle of azygotic meiosis and sporulation. Azygotic meiosis and sporulation occur when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell. FYPO_relaxed.owl FYPO:0004990 biolink:NamedThing G2-exit meiosis with abolished premeiotic DNA replication A cellular process phenotype in which cells in the G2 phase of the mitotic cell cycle undergo meiotic nuclear divisions, and premeiotic DNA replication does not occur. In these cells, sister chromatids precociously segregate at the first meiotic nuclear division. Normally, upon nitrogen starvation cells arrest the mitotic cell in G1 phase, and then proceed into conjugation, premeiotic DNA replication and meiosis. FYPO_relaxed.owl FYPO:0004801 biolink:NamedThing delayed onset of premeiotic DNA replication during azygotic meiosis A cellular process phenotype in which premeiotic DNA replication begins later than normal during a cycle of azygotic meiosis and sporulation. Azygotic meiosis and sporulation occur when meiosis takes place within a diploid cell rather than in a zygote produced by sporulation. Zygotes can resume vegetative growth and form colonies of diploid cells if returned to rich media before commitment to meiosis; under nitrogen starvation, diploid cells heterozygous for mating type will undergo azygotic meiosis. Azygotic asci have a characteristic linear morphology resembling that of a single vegetatively growing cell. FYPO_relaxed.owl FYPO:0006501 biolink:NamedThing premature actin fusion focus assembly A cellular process phenotype in which actin fusion focus assembly begins earlier than normal. An actin fusion focus normally forms during mating at the site where the two cells will fuse. FYPO_relaxed.owl FYPO:0007097 biolink:NamedThing ectopic actin fusion focus assembly A cellular process phenotype in which actin fusion focus assembly takes place in one or more abnormal locations. An actin fusion focus normally forms during mating at the site where the two cells will fuse. Ectopic fusion foci often form near actin cortical patches, and may also have abnormal composition. FYPO_relaxed.owl FYPO:0004806 biolink:NamedThing incomplete cell wall disassembly at cell fusion site A cellular process phenotype in which the cell wall is broken down to a lesser extent than in wild type at the site of cell-cell fusion during mating. FYPO_relaxed.owl FYPO:0006500 biolink:NamedThing premature cell wall disassembly at cell fusion site A cellular process phenotype in which disassembly of the cell wall at the site of cell-cell fusion during mating begins earlier than normal, e.g. before pairing with a partner cell. Premature cell wall breakdown often results in cell lysis. FYPO_relaxed.owl FYPO:0004808 biolink:NamedThing increased cellular protein aggregate level during cellular response to heat A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein present as aggregates of misfolded protein is greater than normal during a cellular response to heat. FYPO_relaxed.owl FYPO:0004810 biolink:NamedThing decreased protein localization to nucleus, with protein mislocalized to cytoplasmic foci A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased, and the protein is instead visible in one or a few foci or dots in the cytoplasm. FYPO_relaxed.owl FYPO:0006191 biolink:NamedThing decreased protein localization to nucleus, with protein mislocalized to cytoplasm during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nucleus is decreased, and some of the protein is present in the cytoplasm instead, during mitosis. FYPO_relaxed.owl FYPO:0004811 biolink:NamedThing abnormal termination of RNA polymerase II transcription A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II is abnormal. Termination of all transcripts, or a subset of transcripts, may be affected. FYPO_relaxed.owl FYPO:0005981 biolink:NamedThing abnormal termination of RNA polymerase I transcription A cell phenotype observed in the vegetative growth phase of the life cycle in which the termination of RNA transcription RNA polymerase I from a DNA template is abnormal. FYPO_relaxed.owl FYPO:0006983 biolink:NamedThing abnormal termination of RNA polymerase III transcription A cell phenotype observed in the vegetative growth phase of the life cycle in which the termination of RNA transcription RNA polymerase III from a DNA template is abnormal. FYPO_relaxed.owl FYPO:0004812 biolink:NamedThing abnormal termination of RNA polymerase II transcription at rDNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II at sites in ribosomal DNA (rDNA) is abnormal. FYPO_relaxed.owl FYPO:0004813 biolink:NamedThing abnormal termination of RNA polymerase II transcription at tDNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II at tRNA genes (tDNA) is abnormal. FYPO_relaxed.owl FYPO:0004814 biolink:NamedThing abnormal termination of RNA polymerase II transcription at highly transcribed protein-coding genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II at highly transcribed protein-coding genes is abnormal. FYPO_relaxed.owl FYPO:0006613 biolink:NamedThing decreased termination of RNA polymerase II transcription A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II occurs to a lower extent than normal. Termination of all transcripts, or a subset of transcripts, may be affected. FYPO_relaxed.owl FYPO:0006614 biolink:NamedThing increased termination of RNA polymerase II transcription A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II occurs to a greater extent than normal. Termination of all transcripts, or a subset of transcripts, may be affected. FYPO_relaxed.owl FYPO:0004817 biolink:NamedThing decreased rDNA antisense small RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from antisense transcription of ribosomal DNA measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0004818 biolink:NamedThing decreased tDNA antisense small RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of small RNA (such as siRNA) derived from antisense transcription of transfer RNA genes measured in a cell is lower than normal. FYPO_relaxed.owl FYPO:0008211 biolink:NamedThing decreased antisense RNA level during heat stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of antisense RNA measured in a cell is lower than normal duing heat stress. Antisense RNA is transcribed from the coding, rather than the template, strand of DNA. FYPO_relaxed.owl FYPO:0004821 biolink:NamedThing decreased number of Rad52 foci at highly transcribed protein-coding genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates at or near highly transcribed protein-coding genes is lower than normal. FYPO_relaxed.owl FYPO:0005677 biolink:NamedThing decreased number of Rad52 foci during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is lower than normal during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006924 biolink:NamedThing decreased number of Rad52 foci at mitotic DNA replication fork barriers A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates at or near replication fork barriers is lower than normal. FYPO_relaxed.owl FYPO:0004822 biolink:NamedThing increased number of R-loops at rDNA A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA-DNA hybrid molecules is greater than normal in ribosomal DNA regions. FYPO_relaxed.owl FYPO:0006495 biolink:NamedThing increased number of R-loops at tRNA genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA-DNA hybrid molecules is greater than normal at tRNA genes. FYPO_relaxed.owl FYPO:0007227 biolink:NamedThing increased number of R-loops at centromere A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA-DNA hybrid molecules is greater than normal in centromeric regions. FYPO_relaxed.owl FYPO:0004825 biolink:NamedThing stably decreased rDNA copy number during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is significantly lower than the range in wild type cells, but remains at the same level over successive generations. FYPO_relaxed.owl FYPO:0006494 biolink:NamedThing decreased rDNA copy number during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is significantly lower than the range in wild type cells. FYPO_relaxed.owl FYPO:0004826 biolink:NamedThing progressively decreasing rDNA copy number during successive meiotic generations A physical cellular phenotype in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is significantly lower than the range in wild type cells, and continues to decrease over successive meiotic generations (i.e. cycles of mating, meiosis, sporulation, spore germination and vegetative growth). FYPO_relaxed.owl FYPO:0007513 biolink:NamedThing increased rDNA copy number during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the number of ribosomal DNA (rDNA) repeats present in the rDNA arrays on chromosome III is significantly greater than the range in wild type cells. FYPO_relaxed.owl FYPO:0004831 biolink:NamedThing decreased protein localization to mitotic spindle midzone during anaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone is decreased during anaphase. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. FYPO_relaxed.owl FYPO:0004833 biolink:NamedThing decreased protein localization to mitotic spindle midzone during anaphase B A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone is decreased during anaphase B. The mitotic spindle midzone is the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap. Anaphase B is the stage of mitosis in which the polar microtubules elongate and the two poles of the spindle move farther apart. FYPO_relaxed.owl FYPO:0006535 biolink:NamedThing increased protein localization to cell periphery during nitrogen starvation A cell phenotype in which the localization of a protein to the cell periphery is increased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0004845 biolink:NamedThing abnormal mitotic DNA replication lagging strand elongation at telomere A cellular process phenotype observed in the vegetative growth phase of the life cycle in which lagging strand elongation during nuclear DNA replication is abnormal at telomeric regions. FYPO_relaxed.owl FYPO:0005748 biolink:NamedThing normal protein export from nucleus during glucose starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein export from nucleus is normal (i.e. indistinguishable from wild type) under conditions of glucose starvation. FYPO_relaxed.owl FYPO:0005880 biolink:NamedThing long interphase microtubules curved around cell end A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form microtubules that are longer than normal and are curved, i.e. follow a smooth bend rather than a straight line, and extend around one or both ends of the cell, during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0004866 biolink:NamedThing enlarged post-anaphase array with increased number of microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the post-anaphase array is larger, and contains more microtubules, than normal. FYPO_relaxed.owl FYPO:0004868 biolink:NamedThing sensitive to ionizing radiation during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to ionizing radiation during G1 phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0009063 biolink:NamedThing sensitive to X-rays during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to X-rays. FYPO_relaxed.owl FYPO:0004872 biolink:NamedThing abolished 2-oxoglutarate dioxygenase activity A molecular function phenotype in which a 2-oxoglutarate-dependent dioxygenase activity is absent. FYPO_relaxed.owl FYPO:0007771 biolink:NamedThing abnormally clustered protein localization to nuclear envelope A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein is abnormally localized to one or more large clusters in the nuclear envelope. The protein may normally be distributed evenly in the nuclear envelope. FYPO_relaxed.owl FYPO:0005613 biolink:NamedThing normal protein localization to nuclear envelope during G0 to G1 transition A cell phenotype in which the localization of a protein to the nuclear envelope is normal (i.e. indistinguishable from wild type) when the cell undergoes transition from G0 phase to G1. FYPO_relaxed.owl FYPO:0004893 biolink:NamedThing normal 1,3-beta-D-glucan synthase activity during vegetative growth A molecular function phenotype in which the observed rate of 1,3-beta-D-glucan synthase activity is normal (i.e. indistinguishable from wild type) during the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0004895 biolink:NamedThing normal rate of actomyosin contractile ring contraction A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actomyosin contractile ring contraction is normal (i.e. indistinguishable from wild type). Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts. FYPO_relaxed.owl FYPO:0005020 biolink:NamedThing normal duration of actomyosin contractile ring contraction A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of actomyosin contractile ring contraction is normal (i.e. indistinguishable from wild type). Contractile ring contraction is the part of cytokinesis in which the actomyosin contractile ring constricts. FYPO_relaxed.owl FYPO:0004912 biolink:NamedThing phytochelatin absent from vacuole A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phytochelatin measured in the vacuole is too low to detect. FYPO_relaxed.owl FYPO:0004920 biolink:NamedThing normal regulation of catalytic activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which regulation of a catalytic activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004921 biolink:NamedThing normal positive regulation of protein kinase activity A regulation phenotype observed in the vegetative growth phase of the life cycle in which positive regulation of a protein kinase activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004925 biolink:NamedThing irregular ascospore wall A physical cellular phenotype in which the outer surface of the ascospore wall is rougher and less regular than normal. FYPO_relaxed.owl FYPO:0004926 biolink:NamedThing increased ascospore wall thickness A physical cellular phenotype in which the outer surface of the ascospore wall is thicker than normal. FYPO_relaxed.owl FYPO:0007604 biolink:NamedThing smooth ascospore wall A physical cellular phenotype in which the outer surface of the spore wall is smooth, lacking the structures than protrude outward from normal spore walls. FYPO_relaxed.owl FYPO:0004936 biolink:NamedThing abolished DNA binding at PCB A molecular function phenotype in which DNA binding at an RNA polymerase II proximal promoter that contains a pombe cell cycle box (PCB) by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007565 biolink:NamedThing abolished DNA binding at MCB A molecular function phenotype in which DNA binding at an RNA polymerase II proximal promoter that contains a Mlu1 cell cycle box (MCB) by a gene product does not occur, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0004954 biolink:NamedThing excess prospore membrane present A physical cellular phenotype in which cells contain more prospore membrane than normal. Excess prospore membrane may take the form of bubble-like structures continuous with the rest of the membrane. FYPO_relaxed.owl FYPO:0004955 biolink:NamedThing decreased phosphatidylinositol-3-phosphate binding A molecular function phenotype in which occurrence of phosphatidylinositol-3-phosphate binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005307 biolink:NamedThing decreased phospholipid binding A molecular function phenotype in which occurrence of phospholipid binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0006776 biolink:NamedThing decreased phosphatidylinositol-4-phosphate binding A molecular function phenotype in which occurrence of phosphatidylinositol-4-phosphate binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0008076 biolink:NamedThing decreased phosphatidylinositol-4,5-bisphosphate binding A molecular function phenotype in which occurrence of phosphatidylinositol-4,5-bisphosphate by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0008077 biolink:NamedThing decreased phosphatidylserine binding A molecular function phenotype in which occurrence of phosphatidylserine binding by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007714 biolink:NamedThing decreased mitochondrial phosphatidylethanolamine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylethanolamine measured in the mitochondrion differs from normal. FYPO_relaxed.owl FYPO:0007715 biolink:NamedThing decreased mitochondrial phosphatidylserine level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylserine measured in the mitochondrion differs from normal. FYPO_relaxed.owl FYPO:0005974 biolink:NamedThing normal mitochondrial protein level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in the mitochondria is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be measured. FYPO_relaxed.owl FYPO:0004963 biolink:NamedThing normal plasma membrane sterol distribution A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in the plasma membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007678 biolink:NamedThing normal sterol distribution A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in cellular membranes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0004967 biolink:NamedThing increased vegetative cell population growth during phosphate starvation A cell growth phenotype in which vegetative cell population growth is increased relative to normal under conditions of phosphate starvation. FYPO_relaxed.owl FYPO:0004971 biolink:NamedThing decreased level of stress responsive gene mRNA during cellular response to phosphate starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more messenger RNAs that are normally expressed during a cellular response to stress measured in a cell is lower than normal (i.e. lower than observed in wild-type cells during vegetative growth) during a cellular response to phosphate starvation. FYPO_relaxed.owl FYPO:0004976 biolink:NamedThing increased rate of microtubule depolymerization ahead of moving spindle pole body A cellular process phenotype observed in the vegetative growth phase of the life cycle in which depolymerization (i.e. removal of tubulin dimers) of microtubules extending in front of a moving spindle pole body occurs at a greater rate, or speed, than normal. FYPO_relaxed.owl FYPO:0004985 biolink:NamedThing entangled telomeres during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form telomeres that become entwined and resistant to separation. FYPO_relaxed.owl FYPO:0005402 biolink:NamedThing increased telomeric 3' overhang length during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the single-stranded telomeric 3' overhang is longer than normal. FYPO_relaxed.owl FYPO:0005403 biolink:NamedThing telomeric 3' overhang absent during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the single-stranded telomeric 3' overhang is not present. Total telomere length may be normal or abnormal. FYPO_relaxed.owl FYPO:0004989 biolink:NamedThing abnormal meiotic centromere clustering resulting in centromere-spindle pole body colocalization during prophase A cellular process phenotype in which centromere clustering is abnormal during one or both meiotic nuclear divisions, such that one or more centromeres is associated with the spindle pole body (SPB) during prophase. Normally, centromeres and SPBs associate after prophase, but not earlier. FYPO_relaxed.owl FYPO:0005640 biolink:NamedThing abnormal meiotic centromere clustering with centromeres dissociated from spindle pole body A cellular process phenotype in which centromere clustering is abnormal during one or both meiotic nuclear divisions, such that centromeres dissociate from the spindle pole body, but do not cluster with each other. FYPO_relaxed.owl FYPO:0007108 biolink:NamedThing abnormal meiotic centromere clustering during meiotic prophase I A cellular process phenotype in which centromere clustering takes place during meiotic prophase I, and remains incomplete. Normally, centromeres and SPBs associate during prometaphase I, but not earlier. FYPO_relaxed.owl FYPO:0004994 biolink:NamedThing delayed onset of meiosis I A cellular process phenotype in which the first meiotic nuclear division begins later than normal. FYPO_relaxed.owl FYPO:0005412 biolink:NamedThing delayed onset of meiosis II A cellular process phenotype in which the second meiotic nuclear division begins later than normal. FYPO_relaxed.owl FYPO:0004999 biolink:NamedThing normal duration of horsetail movement A cellular process phenotype in which the duration of horsetail movement is normal (i.e. indistinguishable from wild type). Horsetail movement is the oscillatory movement of the nucleus that takes place during meiotic prophase I. FYPO_relaxed.owl FYPO:0005012 biolink:NamedThing decreased histone H4-K5 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 5 of histone H4 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005013 biolink:NamedThing decreased histone H4-K8 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005014 biolink:NamedThing decreased histone H4-K12 acetylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 12 of histone H4 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005016 biolink:NamedThing abolished 18S rRNA acetylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the posttranscriptional addition of acetyl groups to residues in an 18S rRNA molecule is abolished. FYPO_relaxed.owl FYPO:0005025 biolink:NamedThing abolished mitotic chromosome centromere condensation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation does not occur in centromeric regions (i.e. adjacent to the kinetochores). FYPO_relaxed.owl FYPO:0005030 biolink:NamedThing increased ribonucleotide incorporation on leading strand A cellular process phenotype observed in the vegetative growth phase of the life cycle in which more ribonucleotides than normal are incorporated into the leading strand during mitotic DNA replication. FYPO_relaxed.owl FYPO:0005031 biolink:NamedThing increased ribonucleotide incorporation on lagging strand A cellular process phenotype observed in the vegetative growth phase of the life cycle in which more ribonucleotides than normal are incorporated into the lagging strand during mitotic DNA replication. FYPO_relaxed.owl FYPO:0005037 biolink:NamedThing normal phosphorylation of RNA polymerase II C-terminal domain serine 5 residues during nitrogen starvation A cellular process phenotype in which the phosphorylation of the serine residue at position 5 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0005040 biolink:NamedThing normal phosphorylation of RNA polymerase II C-terminal domain serine 2 residues during nitrogen starvation A cellular process phenotype in which the phosphorylation of the serine residue at position 2 within one or more copies of the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0007877 biolink:NamedThing normal regulation of translation in response to chemical A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to a chemical stimulus is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005045 biolink:NamedThing abnormal mitotic sister chromatid segregation with lagging chromosomes and decreased rate of mitotic spindle elongation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is decreased, and sister chromatids do not move towards the spindle poles at the same time during mitosis prior to completion of chromosome segregation. FYPO_relaxed.owl FYPO:0005046 biolink:NamedThing abnormal mitotic sister chromatid segregation with lagging chromosomes, complete sister chromatid separation, and decreased rate of mitotic spindle elongation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is decreased, and sister chromatids do not move towards the spindle poles at the same time during mitosis prior to completion of chromosome segregation. Although one or more chromosomes remain distant from the spindle pole after the bulk of the DNA has separated, mitotic sister chromatid segregation does eventually go on to complete separation of chromosomes. FYPO_relaxed.owl FYPO:0005343 biolink:NamedThing decreased rate of mitotic spindle elongation during anaphase B A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is decreased during anaphase B. FYPO_relaxed.owl FYPO:0007960 biolink:NamedThing decreased rate of mitotic spindle elongation during prophase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is decreased during prophase. FYPO_relaxed.owl FYPO:0005047 biolink:NamedThing decreased protein localization to chromatin at RNA polymerase II promoter during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at RNA polymerase II promoters is decreased. FYPO_relaxed.owl FYPO:0005948 biolink:NamedThing decreased protein localization to chromatin at highly transcribed RNA polymerase II genes during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin regions where RNA polymerase II actively transcribes genes is decreased. FYPO_relaxed.owl FYPO:0005068 biolink:NamedThing increased number of double-strand break sites during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites of double-strand breaks in DNA is greater than normal during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005073 biolink:NamedThing decreased mitotic chromosome arm condensation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic chromosome condensation occurs to a lower extent than normal along the chromosome arms. FYPO_relaxed.owl FYPO:0005084 biolink:NamedThing normal protein localization to chromatin at rRNA gene A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at ribosomal RNA (rRNA) genes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005085 biolink:NamedThing normal protein localization to chromatin at snRNA gene A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at small nuclear RNA (snRNA) genes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005086 biolink:NamedThing normal protein localization to chromatin at snoRNA gene A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at small nucleolar RNA (snoRNA) genes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005087 biolink:NamedThing normal protein localization to chromatin at tRNA gene A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at transfer RNA (tRNA) genes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005092 biolink:NamedThing inviable after spore germination, multiple cell divisions, swollen, elongated pear-shaped cell A phenotype in which a spore germinates to produce a cell that has a greater length, diameter, and volume than normal, is shaped in the form of a pear, and undergoes two or more rounds of cell division and then dies. In a pear-shaped cell, one end is rounded, while the other resembles an end of a normal rod-shaped cell. FYPO_relaxed.owl FYPO:0005094 biolink:NamedThing decreased duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by the S-phase DNA damage checkpoint is lower than in wild type during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0005189 biolink:NamedThing abnormal re-entry into mitotic cell cycle after arrest in response to hydroxyurea A cellular process phenotype in which re-entry into the mitotic cell cycle is abnormal after arrest resulting from hydroxyurea exposure. FYPO_relaxed.owl FYPO:0005105 biolink:NamedThing abolished Lys63-specific deubiquitinase activity A molecular function phenotype in which Lys63-specific deubiquitinase activity is absent. FYPO_relaxed.owl FYPO:0005106 biolink:NamedThing decreased Lys63-specific deubiquitinase activity A molecular function phenotype in which the observed rate of Lys63-specific deubiquitinase activity is decreased. FYPO_relaxed.owl FYPO:0005112 biolink:NamedThing decreased ubiquitin-specific protease activity A molecular function phenotype in which the observed rate of ubiquitin-specific protease activity is decreased. FYPO_relaxed.owl FYPO:0005256 biolink:NamedThing decreased carboxypeptidase activity A molecular function phenotype in which the observed rate of a carboxypeptidase activity is decreased. FYPO_relaxed.owl FYPO:0005822 biolink:NamedThing decreased NEDD8-specific protease activity A molecular function phenotype in which the observed rate of NEDD8-specific protease activity (deneddylase activity) is decreased under conditions of glucose starvation. FYPO_relaxed.owl FYPO:0006152 biolink:NamedThing decreased SUMO-specific protease activity A molecular function phenotype in which the observed rate of SUMO-specific protease activity is decreased. FYPO_relaxed.owl FYPO:0005141 biolink:NamedThing decreased meiotic recombination double-strand break repair A cellular process phenotype in which the repair of double-strand breaks formed as part of meiotic recombination is decreased. FYPO_relaxed.owl FYPO:0005618 biolink:NamedThing increased duration of meiotic recombination double-strand break repair A cellular process phenotype in which the duration of repair of double-strand breaks formed as part of meiotic recombination is longer than normal. FYPO_relaxed.owl FYPO:0005911 biolink:NamedThing delayed onset of meiotic recombination double-strand break repair A cellular process phenotype in which the repair of double-strand breaks formed as part of meiotic recombination begins later than normal. FYPO_relaxed.owl FYPO:0005154 biolink:NamedThing decreased protein localization to heterochromatin at mat2P silent mating-type cassette A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at the mat2P silent mating-type cassette is decreased. FYPO_relaxed.owl FYPO:0005164 biolink:NamedThing increased haploidization during cellular response to UV A cell phenotype in which non-sporulating diploid cells become haploid, without undergoing meiosis, at a higher frequency than normal during a cellular response to ultraviolet light. FYPO_relaxed.owl FYPO:0005171 biolink:NamedThing decreased uracil import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of uracil into the cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005172 biolink:NamedThing increased uracil import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of uracil into the cell occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005183 biolink:NamedThing abolished protein polyubiquitination during cellular response to UV A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the polyubiquitination of one or more specific proteins, or of specific protein sites, does not occur when the cell is exposed to ultraviolet light. FYPO_relaxed.owl FYPO:0005212 biolink:NamedThing normal protein localization to kinetochore during mitotic prometaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during prometaphase of mitosis. FYPO_relaxed.owl FYPO:0007399 biolink:NamedThing normal protein localization to kinetochore during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007890 biolink:NamedThing normal protein localization to kinetochore during mitotic spindle assembly checkpoint signaling A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal during mitotic spindle assembly checkpoint signaling. FYPO_relaxed.owl FYPO:0006641 biolink:NamedThing normal protein localization to kinetochore during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during metaphase of mitosis. FYPO_relaxed.owl FYPO:0005214 biolink:NamedThing normal regulation of translation in response to osmotic stress A gene expression phenotype observed in the vegetative growth phase of the life cycle in which regulation of translation in response to osmotic stress is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007383 biolink:NamedThing abolished protein localization to kinetochore during mitotic spindle assembly checkpoint signaling A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome does not occur during mitotic spindle assembly checkpoint signaling. FYPO_relaxed.owl FYPO:0007401 biolink:NamedThing abnormal protein localization to kinetochore during mitotic anaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is abnormal during anaphase of mitosis. FYPO_relaxed.owl FYPO:0007568 biolink:NamedThing normal protein localization to mitotic spindle pole body during anaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is normal (i.e. indistinguishable from wild type) during anaphase. FYPO_relaxed.owl FYPO:0005223 biolink:NamedThing decreased histone H2B localization to chromatin at protein coding gene A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of histone H2B to chromatin at one or more protein-coding genes is decreased. FYPO_relaxed.owl FYPO:0005460 biolink:NamedThing abolished protein localization to chromatin at MCB promoters A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is abolished. FYPO_relaxed.owl FYPO:0005231 biolink:NamedThing loss of viability in stationary phase upon glucose starvation A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after entering stationary phase, when cells the population are subject to glucose starvation. FYPO_relaxed.owl FYPO:0006523 biolink:NamedThing loss of viability in stationary phase following entry from mitotic G2 phase A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after entering stationary phase following arrest at the mitotic G2/M phase transition of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0008123 biolink:NamedThing loss of viability in stationary phase upon phopshate starvation A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after entering stationary phase, when cells the population are subject to phosphate starvation. FYPO_relaxed.owl FYPO:0005462 biolink:NamedThing decreased microtubule-based movement during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule-based movement occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0009005 biolink:NamedThing increased interphase nuclear movement velocity in daughter cell without mitochondria A cellular process phenotype observed in mitotic interphase in which microtubule-based movement oscillations occur at a faster speed than normal in a daughter cell that inherits no mitochondria. FYPO_relaxed.owl FYPO:0009107 biolink:NamedThing increased nuclear movement velocity during mitotic telophase A cellular process phenotype observed in mitotic interphase in which the microtubule-driven movement of daughter nuclei away from the cell tips after mitotic spindle dissambly occurs at a faster speed than normal during telophase. FYPO_relaxed.owl FYPO:0005288 biolink:NamedThing decreased negative regulation of transcription by glucose A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by glucose (glucose repression) occurs to a lower extent than normal. Specific genes that are normally not transcribed in the presence of glucose are transcribed in the mutant. FYPO_relaxed.owl FYPO:0006296 biolink:NamedThing increased negative regulation of transcription by glucose A cellular process phenotype observed in the vegetative growth phase of the life cycle in which negative regulation of transcription by glucose (glucose repression) occurs to a greater extent than normal. Specific genes that are normally not transcribed in the presence of glucose are not derepressed in the mutant under conditions that derepress transcription in wild type cells. FYPO_relaxed.owl FYPO:0005300 biolink:NamedThing decreased protein localization to kinetochore during mitotic spindle assembly checkpoint signaling A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is decreased during mitotic spindle assembly checkpoint signaling. FYPO_relaxed.owl FYPO:0007244 biolink:NamedThing decreased protein localization to kinetochore during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is decreased during metaphase of mitosis. FYPO_relaxed.owl FYPO:0008165 biolink:NamedThing decreased protein localization to kinetochore during mitotic prometaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the kinetochore of a chromosome is decreased during prometaphase of mitosis. FYPO_relaxed.owl FYPO:0007252 biolink:NamedThing decreased membrane lipid binding A molecular function phenotype in which occurrence of binding to a lipid in a membrane by a gene product (usually a protein) in a mutant is decreased. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0005316 biolink:NamedThing increased histone H4-K12 acetylation at subtelomere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 12 of histone H4 in subtelomeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005921 biolink:NamedThing increased histone H4-K12 acetylation at centromere inner repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 12 of histone H4 in centromere inner repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005324 biolink:NamedThing decreased error-free translesion synthesis of cyclobutane pyrimidine dimers A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of cyclobutane pyrimidine dimers by error-free translesion synthesis occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005327 biolink:NamedThing abolished error-free translesion synthesis of cyclobutane pyrimidine dimers A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of cyclobutane pyrimidine dimers by error-free translesion synthesis does not occur. FYPO_relaxed.owl FYPO:0005330 biolink:NamedThing decreased error-free translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of pyrimidine-pyrimidone 6-4 photoproducts by error-free translesion synthesis occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005328 biolink:NamedThing normal error-free translesion synthesis of cyclobutane pyrimidine dimers A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of cyclobutane pyrimidine dimers by error-free translesion synthesis is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005329 biolink:NamedThing normal error-free translesion synthesis of pyrimidine-pyrimidone 6-4 photoproducts A cell phenotype observed in the vegetative growth phase of the life cycle in which the repair of pyrimidine-pyrimidone 6-4 photoproducts by error-free translesion synthesis is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005336 biolink:NamedThing normal level of histone H3 in cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of histone H3 measured in the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005342 biolink:NamedThing normal rate of mitotic spindle elongation during anaphase B A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is normal (i.e. indistinguishable from wild type) during anaphase B. FYPO_relaxed.owl FYPO:0006258 biolink:NamedThing normal rate of mitotic spindle elongation during prophase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is normal (i.e. indistinguishable from wild type) during prophase. FYPO_relaxed.owl FYPO:0005345 biolink:NamedThing mitotic sister chromatid separation during interphase A cellular process phenotype in which mitotic sister chromatid separation begins during interphase of the cell cycle. FYPO_relaxed.owl FYPO:0007914 biolink:NamedThing mitotic sister chromatid separation during metaphase A cellular process phenotype in which mitotic sister chromatid separation occurs during mitotic metaphase. FYPO_relaxed.owl FYPO:0005349 biolink:NamedThing increased spindle pole body-led chromosome movement during mitotic interphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle pole body (SPB) moves rapidly back and forth to a greater extent and over a larger area than normal, causing increased chromosome movement. Normally, SPB oscillation occurs during mitotic interphase (as well as prophase) but is restricted to a small space. FYPO_relaxed.owl FYPO:0005691 biolink:NamedThing decreased spindle pole body-led chromosome movement during mitotic interphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the mitotic spindle pole body (SPB) moves rapidly back and forth to a lower extent and over a smaller area than normal, causing decreased chromosome movement. Normally, SPB oscillation occurs during mitotic interphase (as well as prophase) but is restricted to a small space. FYPO_relaxed.owl FYPO:0007389 biolink:NamedThing abnormal angle of spindle pole body-led chromosome movement during mitotic interphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body (SPB)-led chromosome movement in mitotic interphase takes place at an abnormal angle relative to the long axis of the cell. Normally, the SPB oscillation angle remains nearly parallel to the long axis. FYPO_relaxed.owl FYPO:0007390 biolink:NamedThing increased variability of angle of spindle pole body-led chromosome movement during mitotic interphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which spindle pole body (SPB)-led chromosome movement in mitotic interphase takes place at an angle that varies more than normal. Normally, the SPB oscillation angle remains nearly parallel to the long axis of the cell. FYPO_relaxed.owl FYPO:0005353 biolink:NamedThing normal replication fork arrest at RTS1 barrier A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the RTS1 barrier is normal (i.e. indistinguishable from wild type). Note that the RTS1 barrier usually occurs in the mating type locus, but might be assayed at ectopic loci to maximise the distance that a restarted fork travels. FYPO_relaxed.owl FYPO:0008230 biolink:NamedThing normal replication fork arrest at MPS1 barrier A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the MPS1 barrier located in the mating-type region is normal (i.e. indistinguishable from wild-type). FYPO_relaxed.owl FYPO:0005357 biolink:NamedThing decreased site-specific DNA replication termination at RTS1 barrier A cellular process phenotype observed in the vegetative growth phase of the life cycle in which site-specific DNA replication termination at RTS1 barrier in the mating type region occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005358 biolink:NamedThing increased site-specific DNA replication termination at RTS1 barrier A cellular process phenotype observed in the vegetative growth phase of the life cycle in which site-specific DNA replication termination at RTS1 barrier in the mating type region occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005359 biolink:NamedThing normal termination of RNA polymerase II transcription at RTS1 barrier A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II at the RTS1 replication fork barrier is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006279 biolink:NamedThing normal termination of RNA polymerase II transcription A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase II is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005363 biolink:NamedThing decreased kinetochore microtubule depolymerization during mitotic metaphase chromosome recapture A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle kinetochore microtubule depolymerization, occurs to a lesser extent than normal during mitotic chromosome recapture. FYPO_relaxed.owl FYPO:0005423 biolink:NamedThing decreased mitotic spindle microtubule depolymerization during mitotic anaphase A A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle microtubule depolymerization, i.e. the removal of tubulin dimers from a microtubule in the mitotic spindle, occurs to a lesser extent than normal during anaphase A. FYPO_relaxed.owl FYPO:0005364 biolink:NamedThing decreased rate of kinetochore sliding during chromosome recapture A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of kinetochore sliding, i.e. the movement of a kinetochore along spindle microtubules, during mitotic chromosome recapture is decreased. FYPO_relaxed.owl FYPO:0005365 biolink:NamedThing abolished kinetochore sliding during chromosome recapture A cellular process phenotype observed in the vegetative growth phase of the life cycle in which kinetochore sliding, i.e. the movement of a kinetochore along spindle microtubules, during mitotic chromosome recapture does not occur. FYPO_relaxed.owl FYPO:0006039 biolink:NamedThing incomplete mitotic metaphase chromosome recapture A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic metaphase chromosome recapture does not proceed until the kinetochore has moved all the way to the spindle pole body (SPB), but kinetochores instead pause abnormally near the SPB. FYPO_relaxed.owl FYPO:0006040 biolink:NamedThing abnormal kinetochore microtubule polymerization during mitotic metaphase chromosome recapture A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubules attached to the kinetochore lengthen instead of shortening during mitotic metaphase chromosome recapture. FYPO_relaxed.owl FYPO:0006041 biolink:NamedThing decreased rate of mitotic metaphase chromosome recapture A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic metaphase chromosome recapture is decreased. FYPO_relaxed.owl FYPO:0006042 biolink:NamedThing increased rate of mitotic metaphase chromosome recapture A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic metaphase chromosome recapture is increased. FYPO_relaxed.owl FYPO:0006043 biolink:NamedThing increased rate of kinetochore sliding during chromosome recapture A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of kinetochore sliding, i.e. the movement of a kinetochore along spindle microtubules, during mitotic chromosome recapture is increased. FYPO_relaxed.owl FYPO:0005370 biolink:NamedThing decreased fidelity of double-strand break repair via nonhomologous end joining A cellular process phenotype observed in the vegetative growth phase of the life cycle in which occurrence of errors, usually small deletions, upon repair of double-strand breaks in DNA by nonhomologous end joining is increased. FYPO_relaxed.owl FYPO:0005382 biolink:NamedThing delayed exit from meiosis A cellular process phenotype in which exit from meiosis begins later than normal. FYPO_relaxed.owl FYPO:0007785 biolink:NamedThing abnormal cell cycle arrest at meiotic G2/MI transition A cellular process phenotype in which progression through the meiotic cell cycle is arrested at the G2/MI phase transition. Cells arrested at the G2/MI transition down-even in the presence of nutrients, in contrast with arrest at the mitotic G2/M transition, where cells continue to grow. FYPO_relaxed.owl FYPO:0005390 biolink:NamedThing increased punctate nuclear protein localization during cellular response to ionizing radiation A cell phenotype in which a protein that is normally localized to discrete regions in the nucleus, visible as foci or dots by microscopy, is abnormally localized such that more dots are observed than in normal (wild type) cells during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0005459 biolink:NamedThing abolished double-strand break repair via nonhomologous end joining A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break repair via nonhomologous end joining (NHEJ) does not occur. FYPO_relaxed.owl FYPO:0005401 biolink:NamedThing increased protein level during mitotic G1 cell cycle arrest in response to nitrogen starvation A cell phenotype in which the amount of protein measured in a cell is higher than normal during arrest of the mitotic cell cycle in G1 phase due to nitrogen starvation. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005408 biolink:NamedThing decreased duration of mitotic S phase during cellular response to methyl methanesulfonate A cellular process phenotype in which the duration of progression through S phase of the mitotic cell cycle is shorter than normal during a cellular response to methyl methanesulfonate. FYPO_relaxed.owl FYPO:0005409 biolink:NamedThing normal protein level during cell cycle arrest in mitotic G1 phase in response to nitrogen starvation A cell phenotype in which the amount of protein measured in a cell that has arrested the mitotic cell cycle G1 phase in response to nitrogen starvation is normal (i.e. indistinguishable from wild type). Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005413 biolink:NamedThing increased protein level during meiosis I A cell phenotype in which the amount of protein measured in a cell during the first meiotic nuclear division is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005414 biolink:NamedThing increased protein level during meiosis II A cell phenotype in which the amount of protein measured in a cell during the second meiotic nuclear division is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005415 biolink:NamedThing increased protein level during meiotic anaphase I A cell phenotype in which the amount of protein measured in a cell during anaphase of the first meiotic nuclear division is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005416 biolink:NamedThing increased protein level during meiotic anaphase II A cell phenotype in which the amount of protein measured in a cell during anaphase of the second meiotic nuclear division is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007692 biolink:NamedThing increased DNA strand exchange activator activity A molecular function phenotype in which the activity of a DNA strand exchange activator is increased. FYPO_relaxed.owl FYPO:0007693 biolink:NamedThing decreased DNA strand exchange activator activity A molecular function phenotype in which the activity of a DNA strand exchange activator is decreased. FYPO_relaxed.owl FYPO:0007694 biolink:NamedThing abolished DNA strand exchange activator activity A molecular function phenotype in which the activity of a DNA strand exchange activator is absent. FYPO_relaxed.owl FYPO:0007696 biolink:NamedThing increased DNA strand exchange inhibitor activity A molecular function phenotype in which the activity of a DNA strand exchange inhibitor is increased. FYPO_relaxed.owl FYPO:0007697 biolink:NamedThing decreased DNA strand exchange inhibitor activity A molecular function phenotype in which the activity of a DNA strand exchange inhibitor is decreased. FYPO_relaxed.owl FYPO:0007698 biolink:NamedThing abolished DNA strand exchange inhibitor activity A molecular function phenotype in which the activity of a DNA strand exchange inhibitor is absent. FYPO_relaxed.owl FYPO:0007707 biolink:NamedThing decreased GTPase activator activity A molecular function phenotype in which the activity of a GTPase activator is decreased. FYPO_relaxed.owl FYPO:0007807 biolink:NamedThing decreased endodeoxyribonuclease activator activity A molecular function phenotype in which the activity of a endodeoxyribonuclease activator is decreased. FYPO_relaxed.owl FYPO:0005422 biolink:NamedThing inviable elongated cell with fragmented nucleus and mitotic cell cycle arrest in interphase during cellular response to UV A cell morphology phenotype in which a vegetative cell is inviable and elongated, has a nucleus that is broken into multiple small fragments, and progression through the mitotic cell cycle is arrested in interphase during a cellular response to ultraviolet light. The cell contains no septum. FYPO_relaxed.owl FYPO:0005426 biolink:NamedThing elongated C-shaped vegetative cell with long curved interphase microtubules A cell morphology phenotype in which a vegetatively growing cell is elongated, is curved along the long axis to form a "C" shape, and contains cytoplasmic microtubules that are longer than normal and curved. In a curved cell, the long axis follows a smooth bend rather than a straight line. In a C-shaped cell, the curve is centered at the midpoint of the long axis of the cell. Microtubules curve around the ends of the cell and may become long enough to form loops. FYPO_relaxed.owl FYPO:0005431 biolink:NamedThing decreased mitotic recombination at hotspot A cellular process phenotype in which the occurrence of mitotic recombination at one or more recombination hotspots is decreased to the background level. The basal rate of recombination (i.e. away from hotspots) may remain normal or may be decreased. FYPO_relaxed.owl FYPO:0005432 biolink:NamedThing globally decreased mitotic recombination A cellular process phenotype in which the occurrence of mitotic recombination is decreased both at recombination hotspots and elsewhere in the genome. FYPO_relaxed.owl FYPO:0006281 biolink:NamedThing decreased mitotic recombination at centromere A cellular process phenotype in which the occurrence of mitotic recombination is decreased in centromeric regions. FYPO_relaxed.owl FYPO:0006282 biolink:NamedThing decreased mitotic recombination at chromosome arms A cellular process phenotype in which the occurrence of mitotic recombination is decreased at chromosome arms. FYPO_relaxed.owl FYPO:0005437 biolink:NamedThing normal number of Rad52 foci during cellular response to bleomycin A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is normal (i.e. indistinguishable from wild type) during a cellular response to bleomycin. FYPO_relaxed.owl FYPO:0005680 biolink:NamedThing normal number of Rad52 foci during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the number of sites at which the protein Rad52 (also called Rad22) accumulates is normal (i.e. indistinguishable from wild type) during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005441 biolink:NamedThing abolished protein localization to microtubule during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to one or more microtubules does not occur during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005814 biolink:NamedThing abolished protein localization to microtubule plus-end A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plus ends of microtubules does not occur. FYPO_relaxed.owl FYPO:0006528 biolink:NamedThing decreased proteolysis during meiotic cell cycle A cellular process phenotype in which the occurrence of hydrolysis of peptide bonds within a protein is decreased during the meiotic cell cycle. All proteolysis may be affected, or only cleavage of specific proteins, or even specific sites within specific proteins. FYPO_relaxed.owl FYPO:0005455 biolink:NamedThing telomere assembly at double-strand break site A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere assembly occurs at one or more chromosome ends generated by a double-strand break. FYPO_relaxed.owl FYPO:0005463 biolink:NamedThing decreased spatial extent of interphase microtubule polymerization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cytoplasmic microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a cytoplasmic microtubule during interphase of the mitotic cell cycle, does not continue until microtubules reach the ends of the cell. FYPO_relaxed.owl FYPO:0005681 biolink:NamedThing decreased microtubule polymerization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization, i.e. the addition of tubulin dimers, occurs to a lesser extent than normal. FYPO_relaxed.owl FYPO:0006180 biolink:NamedThing increased microtubule polymerization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization, i.e. the addition of tubulin dimers, occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007955 biolink:NamedThing abnormal rate of microtubule polymerization during vegetative growth A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which the rate or speed of microtubule polymerization, i.e. the additionl of tubulin dimers to a microtubule, is abnormal. FYPO_relaxed.owl FYPO:0005466 biolink:NamedThing protein mislocalized to non-growing cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the non-growing cell tip is observed there. FYPO_relaxed.owl FYPO:0005478 biolink:NamedThing abolished protein phosphorylation during cellular response to arsenite ion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to arsenite ions. FYPO_relaxed.owl FYPO:0005480 biolink:NamedThing increased protein phosphorylation during cellular response to arsenite ion A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during a cellular response to arsenite ions. FYPO_relaxed.owl FYPO:0005489 biolink:NamedThing protein mislocalized to vacuolar membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found in the vacuolar membrane is observed there. FYPO_relaxed.owl FYPO:0005832 biolink:NamedThing abnormal protein transport along microtubule to cell tip cortex during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cortex of the cell tip is abnormal. Transport of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005835 biolink:NamedThing abolished protein transport along microtubule during vegetative growth A transport phenotype observed in the vegetative growth phase of the life cycle in which the transport of proteins along microtubules does not occur. Transport of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005497 biolink:NamedThing abolished transcription from CRE promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements does not occur. FYPO_relaxed.owl FYPO:0005498 biolink:NamedThing increased transcription from CRE promoter during cellular response to miconazole A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements occurs to a greater extent than normal during a cellular response to miconazole. FYPO_relaxed.owl FYPO:0005499 biolink:NamedThing decreased transcription from CRE promoter during cellular response to miconazole A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements occurs to a lower extent than normal during a cellular response to miconazole. FYPO_relaxed.owl FYPO:0005500 biolink:NamedThing abolished transcription from CRE promoter during cellular response to miconazole A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more CRE elements does not occur during a cellular response to miconazole. FYPO_relaxed.owl FYPO:0005512 biolink:NamedThing increased activation of meiosis I spindle assembly checkpoint A cell cycle checkpoint phenotype in which the meiosis I spindle assembly checkpoint is activated more frequently than normal, typically under conditions that do not cause checkpoint activation in wild-type cells. The meiosis I spindle assembly checkpoint normally delays the metaphase/anaphase transition of the first meiotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle. FYPO_relaxed.owl FYPO:0005516 biolink:NamedThing decreased nucleosome occupancy in euchromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal in regions of euchromatin. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0005950 biolink:NamedThing increased nucleosome occupancy at highly transcribed RNA polymerase II genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is greater than normal in chromatin regions where RNA polymerase II actively transcribes genes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0006741 biolink:NamedThing increased nucleosome occupancy at MCB promoters A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is greater than normal at promoters containing one or more MluI cell cycle box factor elements (MCBs). Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0005524 biolink:NamedThing decreased nucleosome occupancy at centromere central core A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal in the central core of the centromeric regions. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0005915 biolink:NamedThing decreased nucleosome occupancy at 5S rRNA genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at the portion of ribosomal DNA encoding 5S rRNA. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0005916 biolink:NamedThing decreased nucleosome occupancy at tRNA genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at tRNA genes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0005931 biolink:NamedThing decreased nucleosome occupancy at silent mating-type cassette A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at the silent mating-type cassettes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0005932 biolink:NamedThing decreased nucleosome occupancy at long terminal repeat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at long terminal repeat (LTR) regions. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0008151 biolink:NamedThing decreased nucleosome occupancy at centromeric heterochromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal in the pericentromeres. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0007722 biolink:NamedThing decreased nucleosome-dependent ATPase activity A molecular function phenotype in which the observed rate of nucleosome-dependent ATPase activity is decreased. FYPO_relaxed.owl FYPO:0005525 biolink:NamedThing decreased nucleosome occupancy at centromere inner repeat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal in centromere inner repeat regions. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0005552 biolink:NamedThing decreased protein localization to cleavage furrow rim A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cleavage furrow rim is decreased. The rim is the part of the cleavage furrow closest to the contractile ring. FYPO_relaxed.owl FYPO:0005562 biolink:NamedThing short stable microtubule bundle A physical cellular phenotype in which stable microtubule bundles are shorter than normal. Stable microtubule bundles, also called Q-MT bundles, are found in quiescent cells. FYPO_relaxed.owl FYPO:0005796 biolink:NamedThing short disorganized microtubule bundle A physical cellular phenotype in which microtubule bundles are shorter than normal and have an abnormal structure. Typically, microtubule bundles do not reach the cell tips and are not aligned parallel to the long axis of the cell. FYPO_relaxed.owl FYPO:0005563 biolink:NamedThing long, thick stable microtubule bundle A physical cellular phenotype in which stable microtubule bundles are longer and thicker than normal. Stable microtubule bundles, also called Q-MT bundles, are found in quiescent cells. FYPO_relaxed.owl FYPO:0005564 biolink:NamedThing short, thin stable microtubule bundle A physical cellular phenotype in which stable microtubule bundles are shorter and thinner than normal. Stable microtubule bundles, also called Q-MT bundles, are found in quiescent cells. FYPO_relaxed.owl FYPO:0005567 biolink:NamedThing T-shaped cell during G0 to G1 transition A cell morphology phenotype in which a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T, when the cell undergoes transition from G0 phase to G1. Cell length is normal. FYPO_relaxed.owl FYPO:0005810 biolink:NamedThing T-shaped cell during recovery from quiescence A cell morphology phenotype in which a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T, when the cell undergoes transition from G0 phase, re-entering the cell cycle phase from which it entered G0 (G1 or G2). Cell length is normal. FYPO_relaxed.owl FYPO:0005792 biolink:NamedThing T-shaped cell during G0 to G2 transition A cell morphology phenotype in which a new growth zone forms along the lateral portion of the cell (often in the middle) before septation, such that a single cell grows in the form of the letter T, when the cell undergoes transition from G0 phase to G2. Cell length is normal. FYPO_relaxed.owl FYPO:0005579 biolink:NamedThing decreased meiotic sister chromatid cohesion at centromere A cellular process phenotype in which cohesion between sister chromatids is decreased in centromeric regions during meiosis. FYPO_relaxed.owl FYPO:0005580 biolink:NamedThing decreased level of lipid metabolism gene mRNA during cellular response to hypoxia A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more lipid metabolism RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells) during a cellular response to hypoxia. Lipid metabolism RNAs are transcribed from genes whose products are involved in any lipid metabolic process. FYPO_relaxed.owl FYPO:0005594 biolink:NamedThing increased protein localization to chromatin at rDNA replication fork barrier A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at a replication fork pausing site within the eukaryotic rDNA repeat spacer is increased. FYPO_relaxed.owl FYPO:0007016 biolink:NamedThing increased protein localization to chromatin at 3' end of rRNA genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the 3' ends of rRNA genes in ribosomal DNA repeat regions is increased. FYPO_relaxed.owl FYPO:0005596 biolink:NamedThing increased protein localization to spindle during meiosis I A cell phenotype in which the localization of a protein to the spindle is increased during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0005635 biolink:NamedThing delayed onset of protein localization to spindle during meiosis I A cell phenotype in which the localization of a protein to the spindle begins later than normal during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007749 biolink:NamedThing decreased protein localization to meiotic spindle during meiosis I A cellular process phenotype in which the localization of a protein to the spindle is decreased during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007856 biolink:NamedThing increased duration of protein localization to spindle during meiosis I A cell phenotype in which the duration of localization of a protein to the spindle is longer than normal during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007993 biolink:NamedThing decreased protein localization to pericentromeric region during meiosis I A cell phenotype observed during the first meiotic nuclear division in which the localization of a protein to chromatin at the pericentromeric regions is decreased. FYPO_relaxed.owl FYPO:0005604 biolink:NamedThing increased duration of Rad52 focus presence during cellular response to ionizing radiation A cell phenotype observed in the vegetative growth phase of the life cycle in which sites at which the protein Rad52 accumulates remain present for longer than normal during a cellular response to ionizing radiation. FYPO_relaxed.owl FYPO:0007075 biolink:NamedThing decreased histone H3-K14 ubiquitination during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 14 of histone H3 occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005608 biolink:NamedThing decreased histone H2B-K119 ubiquitination at double-strand break site during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which ubiquitination of lysine at position 119 of histone H2B occurs to a lower extent than normal in regions surrounding double-strand DNA breaks. Lysine 119 corresponds to the conserved C-terminal lysine of H2B. FYPO_relaxed.owl FYPO:0006020 biolink:NamedThing abnormal protein distribution along RNA polymerase II-transcribed genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is abnormal. FYPO_relaxed.owl FYPO:0007340 biolink:NamedThing increased spatial extent of protein localization to euchromatin A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein localizes to a larger portion of the chromosome than normal in the euchromatic regions. FYPO_relaxed.owl FYPO:0007733 biolink:NamedThing abnormal protein localization to chromatin at 3' end of genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin at the 3' ends of genes is abnormal. FYPO_relaxed.owl FYPO:0005625 biolink:NamedThing normal viability following cellular response to UV during mitotic S phase A cell population phenotype in which a normal proportion of cells in the population remains viable after exposure to ultraviolet light during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005626 biolink:NamedThing normal mitotic G2 DNA damage checkpoint during cellular response to UV during mitotic S phase A cell cycle checkpoint phenotype in which the mitotic G2 DNA damage checkpoint is normal (i.e. indistinguishable from wild type) when the cell is exposed to ultraviolet light during S phase of the mitotic cell cycle. The mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the mitotic cell cycle in response to DNA damage. FYPO_relaxed.owl FYPO:0005627 biolink:NamedThing increased duration of mitotic DNA damage checkpoint during cellular response to UV during mitotic S phase A cell cycle checkpoint phenotype in which the duration of cell cycle arrest or delay due to regulation by any mitotic DNA damage checkpoint is greater than in wild type during a cellular response to ultraviolet (UV) light, when cells are exposed to UV during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005633 biolink:NamedThing sister kinetochore dissociation in meiotic metaphase I, normal chromosome segregation in meiosis I, and sister chromatid non-disjunction in meiosis II A physical cellular phenotype in which sister kinetochores separate during the first meiotic nuclear division, homologous chromosomes undergo normal reductional division, but sister chromatids divide unequally in meiosis II. Normally sister kinetochores remain together until meiosis II. Normally sister kinetochores remain together until meiosis II. FYPO_relaxed.owl FYPO:0005634 biolink:NamedThing sister kinetochore dissociation in meiotic metaphase I with equational sister chromatid segregation in meiosis I A cellular process phenotype in which sister kinetochores become separated during the first meiotic nuclear division, and sister chromatids subsequently separate to result in equational segregation. Equational sister chromatid separation is caused by bi-orientated attachment of sister chromatids. FYPO_relaxed.owl FYPO:0005636 biolink:NamedThing delayed onset of protein localization from kinetochore to spindle during meiosis I A cell phenotype in which the localization of a protein from kinetochores to the spindle begins later than normal during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0005642 biolink:NamedThing abnormal meiotic homologous chromosome biorientation with abnormal kinetochore orientation A cellular process phenotype in which homologous chromosome biorientation is abnormal during meiosis, with chromosomes that are not correctly oriented with the kinetochores facing outwards. Homologous chromosome biorientation is the process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, ensuring that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I. FYPO_relaxed.owl FYPO:0005650 biolink:NamedThing normal onset of premeiotic DNA replication A cellular process phenotype in which premeiotic DNA replication begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events. FYPO_relaxed.owl FYPO:0008243 biolink:NamedThing abnormal nuclear morphology during sporulation A physical cellular phenotype in which the size, shape, or structure of the nucleus is abnormal during sporulation. FYPO_relaxed.owl FYPO:0005653 biolink:NamedThing increased level of iron ion starvation-induced proteins during glutathione starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein encoded by genes normally induced during iron ion starvation measured in a cell is higher than normal when the cell is subject to glutathione starvation. FYPO_relaxed.owl FYPO:0005659 biolink:NamedThing increased frequency of meiotic crossover associated with gene conversion A cellular process phenotype in which the frequency of crossover associated with a gene conversion event during meiotic recombination is increased. FYPO_relaxed.owl FYPO:0005660 biolink:NamedThing decreased frequency of meiotic crossover associated with gene conversion A cellular process phenotype in which the frequency of crossover associated with a gene conversion event during meiotic recombination is decreased. FYPO_relaxed.owl FYPO:0006012 biolink:NamedThing elongated cell with abolished shmoo formation A cell morphology phenotype in which a cell is elongated, and does not form a mating projection under conditions that normally induce shmooing. FYPO_relaxed.owl FYPO:0007435 biolink:NamedThing inviable elongated mononucleate cell during nitrogen starvation A cell phenotype in which a cell is inviable, elongated, i.e. has a greater length and length:diameter ratio than normal, and has one nucleus when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0005668 biolink:NamedThing sensitive to cAMP A phenotype observed in the vegetative growth phase of the life cycle in which cells show increased sensitivity to cyclic AMP (cAMP). Cells stop growing (and may die) at a concentration of cAMP that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0005673 biolink:NamedThing decreased level of ubiquitinated protein in cell during cellular response to methyl methanesulfonate A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ubiquitinated protein measured the cell is lower than normal during a cellular response to methyl methanesulfonate. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005674 biolink:NamedThing increased level of ubiquitinated protein in cell during cellular response to methyl methanesulfonate A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ubiquitinated protein measured the cell is higher than normal during a cellular response to methyl methanesulfonate. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005678 biolink:NamedThing ubiquitinated protein absent from cell during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of ubiquitinated protein measured in a cell is too low to detect. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0006758 biolink:NamedThing protein absent from cell during mitotic G1 phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell is too low to detect during G1 phase of the mitotic cell cycle. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007302 biolink:NamedThing protein absent from cell during heat shock A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell is too low to detect when the cell is subject to heat shock. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005684 biolink:NamedThing increased duration of mitotic prometaphase A cellular process phenotype in which the duration of progression through prometaphase of mitosis is longer than normal. FYPO_relaxed.owl FYPO:0007485 biolink:NamedThing abolished meiotic spindle microtubule nucleation from new spindle pole body during meiosis II A cellular process phenotype in which nucleation of spindle microtubules from the new spindle pole body does not occur during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0005694 biolink:NamedThing decreased interphase microtubule nucleation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules occurs to a lower extent than normal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006336 biolink:NamedThing decreased mitotic microtubule nucleation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleation of microtubules from one or more microtubule organizing centers (MTOCs) occurs to a lesser extent than normal during mitosis. FYPO_relaxed.owl FYPO:0005697 biolink:NamedThing abolished cytoplasmic interphase microtubule nucleation from spindle pole body A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules from the spindle pole body (SPB) does not occur during interphase of the mitotic cell cycle. Normally, microtubules are nucleated from interphase microtubule organizing centers (iMTOCs) and from the cytoplasmic face of the SPB. FYPO_relaxed.owl FYPO:0005699 biolink:NamedThing normal interphase microtubule nucleation from spindle pole body A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules from the spindle pole body (SPB) normal (i.e. indistinguishable from wild type) during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0005703 biolink:NamedThing decreased rate of microtubule polymerization during vegetative growth A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule, occurs at a lower rate, or speed, than normal. FYPO_relaxed.owl FYPO:0008032 biolink:NamedThing normal mitotic spindle checkpoint activation A cell cycle checkpoint phenotype in which the mitotic cell cycle spindle assembly checkpoint activation is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005733 biolink:NamedThing increased glutamate-ammonia ligase activity during cellular response to iron ion starvation A molecular function phenotype in which the observed rate of glutamate-ammonia ligase activity is increased during a cellular response to iron ion starvation. FYPO_relaxed.owl FYPO:0005734 biolink:NamedThing decreased glutamate dehydrogenase (NADP+) activity during cellular response to iron ion starvation A molecular function phenotype in which the observed rate of glutamate dehydrogenase activity using NAPD+ as a cofactor is decreased during a cellular response to iron ion starvation. FYPO_relaxed.owl FYPO:0005739 biolink:NamedThing complete but unequal mitotic sister chromatid segregation with unseparated chromosomes A cellular process phenotype in which mitotic sister chromatid segregation results in the division of chromosomes into two distinct unequal masses containing unseparated sister chromatids, located at or near the ends of an elongated mitotic spindle. FYPO_relaxed.owl FYPO:0005759 biolink:NamedThing increased protein localization to chromatin at late replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at late-firing replication origins is increased. FYPO_relaxed.owl FYPO:0005761 biolink:NamedThing normal protein O-linked glycosylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein glycosylation is normal (i.e. indistinguishable from wild type). Protein O-linked glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid via a hydroxyl or phenol group, forming an O-glycan. FYPO_relaxed.owl FYPO:0007288 biolink:NamedThing normal protein galactosylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein galactosylation is normal (i.e. indistinguishable from wild type). Protein galactosylation is the addition of a galactose residue to a protein amino acid. FYPO_relaxed.owl FYPO:0005764 biolink:NamedThing increased replication fork pausing at G4 motif A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork pausing occurs to a greater extent than normal in regions containing G-quartet (G4) motifs. FYPO_relaxed.owl FYPO:0005765 biolink:NamedThing increased replication fork pausing at highly transcribed RNA polymerase II genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork pausing occurs to a greater extent than normal in regions where RNA polymerase II actively transcribes genes. FYPO_relaxed.owl FYPO:0005766 biolink:NamedThing increased replication fork pausing at nucleosome-depleted regions A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork pausing occurs to a greater extent than normal in regions where nucleosomes are depleted. FYPO_relaxed.owl FYPO:0005767 biolink:NamedThing increased replication fork pausing at tRNA genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork pausing occurs to a greater extent than normal at tRNA genes. FYPO_relaxed.owl FYPO:0005768 biolink:NamedThing increased replication fork pausing at rDNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork pausing occurs to a greater extent than normal at ribosomal DNA. FYPO_relaxed.owl FYPO:0005786 biolink:NamedThing decreased spatial extent of double-strand break processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break processing extends for a shorter distance from the breaks site than normal. Double-strand break processing is the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang. FYPO_relaxed.owl FYPO:0006666 biolink:NamedThing increased spatial extent of double-strand break processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which double-strand break processing extends for a longer distance from the breaks site than normal. Double-strand break processing is the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang. FYPO_relaxed.owl FYPO:0007031 biolink:NamedThing abolished protein localization to cell cortex of cell tip during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips does not occur during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0008075 biolink:NamedThing increased protein localization to cell cortex of cell tip during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex of one or both cell tips is increased. FYPO_relaxed.owl FYPO:0005801 biolink:NamedThing decreased rate of protein movement within plasma membrane at cell tip A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of one or more proteins within the plasma membrane of the cell tip occurs more slowly than normal. FYPO_relaxed.owl FYPO:0005802 biolink:NamedThing increased rate of protein movement within plasma membrane at cell tip A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of one or more proteins within the plasma membrane of the cell tip occurs more quickly than normal. FYPO_relaxed.owl FYPO:0005803 biolink:NamedThing decreased rate of protein movement within plasma membrane at cell side A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the movement of one or more proteins within the plasma membrane of the lateral part of the cell occurs more slowly than normal. FYPO_relaxed.owl FYPO:0005808 biolink:NamedThing normal rate of protein movement within spore plasma membrane A cellular process phenotype in which the rate, or speed, of movement of one or more proteins within the plasma membrane of a spore is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005805 biolink:NamedThing normal rate of protein movement within plasma membrane at cell tip A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of movement of one or more proteins within the plasma membrane of the cell tip is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005806 biolink:NamedThing normal rate of protein movement within plasma membrane at cell side A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of movement of one or more proteins within the plasma membrane of the lateral part of the cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005809 biolink:NamedThing short astral microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form astral microtubules that are shorter than normal. FYPO_relaxed.owl FYPO:0007546 biolink:NamedThing abolished nuclear envelope division A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear envelope division does not occur. Nuclear envelope division takes place at the end of mitosis; the nuclear envelope undergoes localized breakdown in the nuclear bridge midzone and the ends are sealed and retrieved into the envelopes of the separated daughter nuclei. When nuclear envelope division does not occur, the two DNA masses remain linked by the nuclear bridge, and may coalesce back into a single nucleus. FYPO_relaxed.owl FYPO:0007548 biolink:NamedThing abnormal mitotic nuclear bridge midzone membrane domain organization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nuclear envelope organization is abnormal in the region of the nuclear envelope that surrounds the mitotic nuclear bridge during mitosis. FYPO_relaxed.owl FYPO:0007772 biolink:NamedThing delayed onset of mitotic nuclear membrane reassembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which reformation of the nuclear envelope after mitotic nuclear division begins later than normal. FYPO_relaxed.owl FYPO:0008124 biolink:NamedThing increased nuclear envelope SPB fenestra size A abnormal nuclear envelope organization phenotype in which SPB fenestra in the nuclear envelope are larger than normal. SPB fenestra are the result of SPB extrusion. FYPO_relaxed.owl FYPO:0008125 biolink:NamedThing increased duration of nuclear envelope SPB fenestra A abnormal nuclear envelope organization phenotype in which SPB fenestra in the nuclear envelope are present for longer than normal. FYPO_relaxed.owl FYPO:0005820 biolink:NamedThing increased protein neddylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of neddylation of one or more specific proteins, or of specific protein sites, is increased. FYPO_relaxed.owl FYPO:0008208 biolink:NamedThing abolished protein neddylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the neddylation of one or more specific proteins, or of specific protein sites, is abolished. FYPO_relaxed.owl FYPO:0005834 biolink:NamedThing decreased protein transport along microtubule to cell tip cortex during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached, is decreased. Transport of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005837 biolink:NamedThing abolished protein transport along microtubule to cell tip cortex during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cortex of the cell tip does not occur. Transport of all proteins or a specific protein may be affected. FYPO_relaxed.owl FYPO:0005841 biolink:NamedThing normal protein transport along microtubule to cell tip cortex during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein transport along microtubules to the cortex of the cell tip is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005991 biolink:NamedThing normal protein localization to cell cortex of cell tip during karyogamy A cell phenotype in which the localization of a protein to the cell cortex of the cell tip during karyogamy involved in conjugation with cellular fusion is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005847 biolink:NamedThing decreased histone methyltransferase activity (H3-K9 specific) activity A molecular function phenotype in which the observed rate of H3-K9 specific histone methyltransferase activity is decreased. FYPO_relaxed.owl FYPO:0005850 biolink:NamedThing abolished protein localization to heterochromatin at centromere outer repeat A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to heterochromatin at centromere outer repeat regions does not occur. FYPO_relaxed.owl FYPO:0005868 biolink:NamedThing increased mitotic recombination at rDNA A cellular process phenotype in which the occurrence of mitotic recombination is increased at ribosomal DNA. FYPO_relaxed.owl FYPO:0005905 biolink:NamedThing normal onset of actomyosin contractile ring assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which contractile ring assembly begins at the normal (i.e. indistinguishable from wild type) time relative to other cell cycle events. FYPO_relaxed.owl FYPO:0006187 biolink:NamedThing normal rate of actomyosin contractile ring assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actomyosin contractile ring assembly is normal (i.e. indistinguishable from wild type). Contractile ring assembly is the part of cytokinesis in which the actomyosin contractile ring is formed of actin, myosin, and associated proteins. FYPO_relaxed.owl FYPO:0007944 biolink:NamedThing abnormal chromatin loop formation during meiotic prophase I A cellular process phenotype in which any process of chromatin loop formation is abnormal during meiotic prophase I. FYPO_relaxed.owl FYPO:0005914 biolink:NamedThing elongated linear element A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form linear element that are longer than normal. FYPO_relaxed.owl FYPO:0007802 biolink:NamedThing short linear element A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form linear element that are shorter than normal. FYPO_relaxed.owl FYPO:0005923 biolink:NamedThing increased H2A.Z level at subtelomere A cell phenotype in which the amount of the histone variant H2A.Z found associated with chromatin in subtelomeric regions is higher than normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0005924 biolink:NamedThing increased H2A.Z level at centromere inner repeat A cell phenotype in which the amount of the histone variant H2A.Z found associated with chromatin in centromere inner repeat regions is higher than normal when the cell is in the vegetative growth phase of the life cycle. FYPO_relaxed.owl FYPO:0005937 biolink:NamedThing decreased protein localization to chromatin at late replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at late replication origins is decreased. FYPO_relaxed.owl FYPO:0005938 biolink:NamedThing normal protein localization to chromatin at late replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at late replication origins is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005943 biolink:NamedThing decreased break-induced loss of heterozygosity via chromosomal translocation A cell phenotype observed in the vegetative growth phase of the life cycle in which chromosomal translocation that would result in the loss of one of two different alleles of a gene occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005944 biolink:NamedThing increased break-induced loss of heterozygosity via chromosomal truncation A cell phenotype observed in the vegetative growth phase of the life cycle in which chromosomal truncation that would result in the loss of one of two different alleles of a gene occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0005949 biolink:NamedThing normal protein localization to chromatin at highly transcribed RNA polymerase II genes during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin regions where RNA polymerase II actively transcribes genes is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006021 biolink:NamedThing normal protein distribution along RNA polymerase II-transcribed genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0005951 biolink:NamedThing decreased nucleosome occupancy at highly transcribed RNA polymerase II genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal in chromatin regions where RNA polymerase II actively transcribes genes. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0005957 biolink:NamedThing decreased protein dephosphorylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dephosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006837 biolink:NamedThing increased protein dephosphorylation during cytokinesis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dephosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during cytokinesis. FYPO_relaxed.owl FYPO:0005958 biolink:NamedThing decreased protein dephosphorylation during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dephosphorylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal during mitosis. FYPO_relaxed.owl FYPO:0005963 biolink:NamedThing decreased sodium import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of sodium ions into a cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005965 biolink:NamedThing decreased lithium import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of lithium ions into a cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005967 biolink:NamedThing decreased potassium import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of potassium ions into a cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005976 biolink:NamedThing increased rate of mitotic spindle elongation during anaphase B A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is increased during anaphase B. FYPO_relaxed.owl FYPO:0007071 biolink:NamedThing increased rate of mitotic spindle elongation during anaphase A A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is increased during anaphase a. FYPO_relaxed.owl FYPO:0007959 biolink:NamedThing increased rate of mitotic spindle elongation during prophase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of mitotic spindle elongation is increased during miotic prophase. FYPO_relaxed.owl FYPO:0005978 biolink:NamedThing increased spliced cen-dg RNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which spliced forms of RNAs transcribed from dg repeats in the centromere outer repeat region are present at higher levels than normal. FYPO_relaxed.owl FYPO:0005980 biolink:NamedThing decreased actin filament bundle assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the assembly of actin filament bundles is decreased. FYPO_relaxed.owl FYPO:0005983 biolink:NamedThing decreased potassium export A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the export of potassium ions out of a cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0005990 biolink:NamedThing abnormal maintenance of protein location in cell cortex of cell tip during karyogamy A cell phenotype in which a protein is localized to the cell cortex of the cell tip during karyogamy involved in conjugation with cellular fusion, but does not remain there continuously. FYPO_relaxed.owl FYPO:0006009 biolink:NamedThing actin cables present in decreased numbers during cytokinesis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer actin cables than normal during cytokinesis. FYPO_relaxed.owl FYPO:0006013 biolink:NamedThing large ascus A phenotype in which the ascus is larger than normal. FYPO_relaxed.owl FYPO:0006030 biolink:NamedThing actin cortical patches absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the cell does not contain detectable actin cortical patches. FYPO_relaxed.owl FYPO:0006045 biolink:NamedThing delayed onset of mitotic sister chromatid biorientation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid biorientation begins later than normal. FYPO_relaxed.owl FYPO:0006049 biolink:NamedThing fluctuating mitotic spindle length A cell phenotype in which a mitotic spindle assembles, but then undergoes large changes in length, instead of remaining at a constant length or gradually elongating. FYPO_relaxed.owl FYPO:0006062 biolink:NamedThing ectopic septin ring assembly during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which one septin ring assembles in the normal location, but one or more additional septin rings also form in abnormal locations. FYPO_relaxed.owl FYPO:0006063 biolink:NamedThing septin ring assembly during mitotic interphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septin ring assembly begins in mitotic interphase instead of during nuclear division. FYPO_relaxed.owl FYPO:0006065 biolink:NamedThing delayed onset of septin ring disassembly during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septin ring disassembly begins later than normal. FYPO_relaxed.owl FYPO:0006069 biolink:NamedThing increased small RNA binding A molecular function phenotype in which an interaction between a protein and a small RNA (sRNA) is increased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0007325 biolink:NamedThing increased tRNA binding A molecular function phenotype in which an interaction between a protein and a transfer RNA (tRNA) is increased. One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0006075 biolink:NamedThing increased mature 25S rRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of the mature 25S rRNA measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006941 biolink:NamedThing increased duration of protein localization to actin cortical patch A cell phenotype observed in the vegetative growth phase of the life cycle in which one or more proteins is localized to actin cortical patches for a longer time than normal. FYPO_relaxed.owl FYPO:0006084 biolink:NamedThing sensitive to cold shock A cell phenotype in which cells show increased sensitivity to cold shock. Cold shock is a form of temperature stress in which cells are briefly exposed to a very low temperature. FYPO_relaxed.owl FYPO:0006099 biolink:NamedThing decreased protein localization to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is decreased. FYPO_relaxed.owl FYPO:0006552 biolink:NamedThing increased protein localization to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is increased. FYPO_relaxed.owl FYPO:0007583 biolink:NamedThing decreased protein localization to cytoplasm during mitotic telophase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is decreased during telophase of mitosis. FYPO_relaxed.owl FYPO:0006101 biolink:NamedThing abnormal interphase microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the morphology of cytoplasmic microtubules is abnormal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006115 biolink:NamedThing increased protein oxidation during mitotic S phase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of oxidation of one or more specific proteins, or of specific protein sites, is increased, resulting in the accumulation of proteins with oxidative modifications including carbonylated proteins, during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006126 biolink:NamedThing normal poly(A) RNA binding A molecular function phenotype in which an interaction between a protein and polyadenylated RNA (poly(A) RNA) is normal (i.e. indistinguishable from wild type). One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0006253 biolink:NamedThing normal tRNA binding A molecular function phenotype in which an interaction between a protein and transfer RNA (tRNA) is normal (i.e. indistinguishable from wild type). One of the relevant gene products may be encoded by the mutated gene, or both the RNA and protein may be encoded by genes other than the mutated one. FYPO_relaxed.owl FYPO:0006127 biolink:NamedThing increased protein oligomerization A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein oligomerization is increased. FYPO_relaxed.owl FYPO:0006128 biolink:NamedThing normal duration of meiosis II A cellular process phenotype in which the duration of the second meiotic nuclear division is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006159 biolink:NamedThing increased protein localization to linear element A cell phenotype in which the localization of a protein to linear elements is increased. FYPO_relaxed.owl FYPO:0006164 biolink:NamedThing decreased protein localization to linear element A cell phenotype in which the localization of a protein to linear elements is decreased. FYPO_relaxed.owl FYPO:0006171 biolink:NamedThing mitotic spindle elongation during anaphase A A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle elongation takes place during anaphase A. Normally, the spindle elongates immediately following assembly during prophase, remains at a static length during metaphase and anaphase A, and elongates further during anaphase B. FYPO_relaxed.owl FYPO:0006174 biolink:NamedThing abolished mitotic spindle elongation during anaphase B A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic spindle elongation does not occur during anaphase B. Normally, the spindle elongates immediately following assembly during prophase, remains at a static length during metaphase and anaphase A, and elongates further during anaphase B. FYPO_relaxed.owl FYPO:0006181 biolink:NamedThing decreased protein localization to cytoplasm, with protein mislocalized to nucleus, during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cytoplasm is decreased, and some of the protein is present in the nucleus instead, during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007472 biolink:NamedThing abnormal histone turnover A cellular process phenotype in which histone exchange is abnormal. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. FYPO_relaxed.owl FYPO:0006190 biolink:NamedThing long mitotic spindle during anaphase A A spindle phenotype in which the mitotic spindle is longer than normal during anaphase A. FYPO_relaxed.owl FYPO:0006205 biolink:NamedThing normal cellular dGTP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dGTP measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007433 biolink:NamedThing normal cellular dATP level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of dATP measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006212 biolink:NamedThing inviable after spore germination, before germ tube formation, during copper ion starvation A phenotype in which a spore germinates but dies before forming a germ tube or dividing, when spore germination takes place under conditions of copper ion starvation. Such spores exit dormancy and undergo isotropic swelling but the spore wall does not rupture and no germ tube emerges. FYPO_relaxed.owl FYPO:0006214 biolink:NamedThing decreased spore germination frequency during copper ion starvation A cell population phenotype in which the frequency of occurrence of spore germination is decreased when germination takes place under conditions of copper ion starvation. FYPO_relaxed.owl FYPO:0006224 biolink:NamedThing decreased ferrous iron import A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the import of ferrous iron ions into a cell occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006228 biolink:NamedThing increased plasma membrane potential A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the plasma membrane potential, i.e. the electric potential existing across the plasma membrane, is greater than normal. FYPO_relaxed.owl FYPO:0006236 biolink:NamedThing normal cytosolic monomeric ribosome level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain a normal (i.e. indistinguishable from wild type) number of monomeric ribosomes (80S monosomes) in the cytosol. FYPO_relaxed.owl FYPO:0006237 biolink:NamedThing normal cytosolic half-mer polysome level A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain a normal (i.e. indistinguishable from wild type) number of half-mer polysomes in the cytosol. A half-mer polysome is a complex consisting of an mRNA bound to a single small ribosomal subunit, followed by one or more complete bound ribosomes. FYPO_relaxed.owl FYPO:0006247 biolink:NamedThing premature mitotic G2/M phase transition during cellular response to osmotic stress A cell cycle phenotype in which the G2/M transition of the mitotic cell cycle begins earlier than normal during a cellular response to osmotic stress. The duration of G2 phase is thus shorter than normal. The mitotic G2/M transition is the point at which a cell commits to entering M phase, and begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. FYPO_relaxed.owl FYPO:0006248 biolink:NamedThing increased centromere clustering at nuclear periphery during mitosis A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of centromeres and associated kinetochores into a cluster at the nuclear periphery is increased during mitosis. Normally, centromere-kinetochore complexes cluster near the old spindle pole body during interphase of the mitotic cell cycle, but are not as tightly clustered during mitosis. FYPO_relaxed.owl FYPO:0006800 biolink:NamedThing decreased centromere clustering at nuclear periphery during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of centromeres and associated kinetochores into a cluster at the nuclear periphery is decreased during interphase of the mitotic cell cycle. Centromere-kinetochore complexes normally cluster near the old spindle pole body during mitotic interphase. FYPO_relaxed.owl FYPO:0006251 biolink:NamedThing decreased tRNA aminoacylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which tRNA aminoacylation, the formation of an ester bond between a tRNA molecule and an amino acid specified by the tRNA anticodon, is decreased. All tRNAs aminoacylation may be decreased, or the aminoacylation of one or more specific tRNAs may be affected. FYPO_relaxed.owl FYPO:0006255 biolink:NamedThing increased level of short ribosome footprints during endoplasmic reticulum unfolded protein response A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of ribosomal footprint lengths in a cell includes more short footprints than wild type when the cell undergoes an endoplasmic reticulum unfolded protein response (UPR). Ribosomal footprints are RNA fragments protected by the ribosome, and normally range from 28-31 nucleotides long. FYPO_relaxed.owl FYPO:0006259 biolink:NamedThing normal mitotic spindle length during metaphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the length of the mitotic spindle is normal (i.e. indistinguishable from wild type) during metaphase. FYPO_relaxed.owl FYPO:0006261 biolink:NamedThing abolished histone H3-K36 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 36 of histone H3 does not occur. FYPO_relaxed.owl FYPO:0006264 biolink:NamedThing decreased telomeric DNA separation during anaphase B A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitotic sister chromatid separation is decreased at the telomeric regions during anaphase B. The remainder of the sister chromatids may or may not separate normally. FYPO_relaxed.owl FYPO:0006266 biolink:NamedThing normal vacuole size during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size of the fungal-type vacuole is normal (i.e. indistinguishable from wild type).. FYPO_relaxed.owl FYPO:0007008 biolink:NamedThing normal termination of RNA polymerase III transcription A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the termination of transcription by RNA polymerase III is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006285 biolink:NamedThing increased duration of protein localization to telomere during mitotic anaphase B A cell phenotype observed in the vegetative growth phase of the life cycle in which the duration of localization of a protein to the telomere of a chromosome is longer than normal during anaphase B of mitosis. FYPO_relaxed.owl FYPO:0006289 biolink:NamedThing increased cellular phytoceramide level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of a phytoceramide measured in a cell is higher than normal. FYPO_relaxed.owl FYPO:0006293 biolink:NamedThing normal protein localization via NVT pathway A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the vacuole lumen via the NVT pathway is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006294 biolink:NamedThing normal macroautophagy during nitrogen starvation A cellular process phenotype in which macroautophagy is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation. Macroautophagy is the major pathway by which cells digest parts of their own cytoplasm. FYPO_relaxed.owl FYPO:0007444 biolink:NamedThing normal macroautophagy during cellular response to endoplasmic reticulum stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which macroautophagy is normal (i.e. indistinguishable from wild type) during a cellular response to endoplasmic reticulum stress. FYPO_relaxed.owl FYPO:0006295 biolink:NamedThing abolished macroautophagy during nitrogen starvation A cellular process phenotype in which macroautophagy does not occur when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0007447 biolink:NamedThing abolished reticulophagy during cellular response to endoplasmic reticulum stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which autophagic degradation of the endoplasmic reticulum does not occur during a cellular response to endoplasmic reticulum stress. FYPO_relaxed.owl FYPO:0007500 biolink:NamedThing abolished macroautophagy during sulfur starvation A cellular process phenotype in which macroautophagy does not occur when the cell is subject to sulfur starvation. FYPO_relaxed.owl FYPO:0007803 biolink:NamedThing abolished macroautophagy during leucine starvation A cellular process phenotype in which macroautophagy does not occur when the cell is subject to leucine starvation. FYPO_relaxed.owl FYPO:0006303 biolink:NamedThing decreased protein localization to actomyosin contractile ring, with protein mislocalized to cytoplasm A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the actomyosin contractile ring is decreased, and some of the protein is present in the cytoplasm instead. FYPO_relaxed.owl FYPO:0006314 biolink:NamedThing abolished ascus formation A cell phenotype in which formation of the ascus, the sac-like structure that encloses spores, does not occur. FYPO_relaxed.owl FYPO:0006317 biolink:NamedThing decreased protein localization to meiotic spindle pole body during meiosis II A cell phenotype in which the localization of a protein to the meiotic spindle pole body is decreased during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0007482 biolink:NamedThing decreased protein localization to meiotic spindle pole body during meiosis I A cell phenotype in which the localization of a protein to the meiotic spindle pole body is decreased during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006332 biolink:NamedThing normal mating efficiency during stationary phase A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is normal (i.e. the same as in wild-type cells) when the population in which the mating cells are found is in stationary phase. FYPO_relaxed.owl FYPO:0007963 biolink:NamedThing normal mating efficiency during nitrogen stress A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is normal (i.e. the same as in wild-type cells) during nitrogen limitation or poor nitrogen source. FYPO_relaxed.owl FYPO:0006337 biolink:NamedThing decreased interphase microtubule nucleation from spindle pole body A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of cytoplasmic microtubules from the spindle pole body (SPB) occurs to a lesser extent than normal during interphase of the mitotic cell cycle. Normally, microtubules are nucleated from interphase microtubule organizing centers (iMTOCs) and from the cytoplasmic face of the SPB. FYPO_relaxed.owl FYPO:0006338 biolink:NamedThing nucleus mislocalized towards cell tip during mitotic telophase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the divided nuclei are located near the cell tips (instead of at the midpoint of the long axis of each daughter cell) during telophase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0009106 biolink:NamedThing nucleus mislocalized towards cell equator during mitotic telophase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the divided nuclei are located closer to the cell equator during telophase of the mitotic cell cycle when compared to wild-type cells. FYPO_relaxed.owl FYPO:0007150 biolink:NamedThing decreased microtubule bundle formation A cellular process phenotype in which the occurrence of microtubule bundle formation, which normally results in a parallel arrangement of microtubules, is decreased. FYPO_relaxed.owl FYPO:0006363 biolink:NamedThing monopolar spindle during meiosis I A physical cellular phenotype in which the spindle forms with microtubules emanating from only one pole during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006364 biolink:NamedThing spindle microtubules detached from spindle pole body during meiosis I A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which meiotic spindle microtubules become disconnected from the spindle pole body during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006383 biolink:NamedThing abnormal sporulation resulting in formation of ascus containing non-uniform spores and unencapsulated DNA A sporulation phenotype that results in the formation of an ascus that contains spores of non-uniform size and DNA content, as well as DNA that is not contained within any of the spores. There may also be fewer than four spores. FYPO_relaxed.owl FYPO:0006386 biolink:NamedThing protein abnormally dispersed at shmoo tip A cell phenotype in which a protein that normally localizes to a compact region at the tip of a shmoo, or mating projection, is more dispersed than normal. FYPO_relaxed.owl FYPO:0007667 biolink:NamedThing increased protein localization to shmoo tip A cell phenotype in which the localization of a protein to the tip of a shmoo, or mating projection, is decreased. FYPO_relaxed.owl FYPO:0006392 biolink:NamedThing abolished protein localization to meiotic spindle pole body during meiosis I A cell phenotype in which the localization of a protein to the meiotic spindle pole body is abolished during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007246 biolink:NamedThing abolished protein localization to meiotic spindle pole body during anaphase II A cell phenotype in which the localization of a protein to the meiotic spindle pole body is abolished during anaphase of the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0007999 biolink:NamedThing abolished protein localization to spindle pole body during karyogamy A cell phenotype in which the localization of a protein to the spindle pole body is abolished during karyogamy. FYPO_relaxed.owl FYPO:0006402 biolink:NamedThing abolished histone H3-K36 trimethylation at promoter during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 36 of histone H3 in one or more promoter regions does not occur. FYPO_relaxed.owl FYPO:0006411 biolink:NamedThing abolished histone RNA level oscillation during mitotic cell cycle A gene expression phenotype in which the levels of RNAs that encode histones, which normally vary over the course of the mitotic cell cycle, remain constant. All RNAs encoding histones, or one or more specific histone RNA, may be affected. FYPO_relaxed.owl FYPO:0006412 biolink:NamedThing decreased level of histone gene mRNA during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more histone RNAs measured in a cell is lower than normal (i.e. lower than observed in wild-type cells) during S phase of the mitotic cell cycle. Histone RNAs are transcribed from genes encoding histones. FYPO_relaxed.owl FYPO:0006414 biolink:NamedThing increased level of histone gene mRNA during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more histone RNAs measured in a cell is higher than normal (i.e. lower than observed in wild-type cells) during interphase of the mitotic cell cycle. Histone RNAs are transcribed from genes encoding histones. FYPO_relaxed.owl FYPO:0006422 biolink:NamedThing increased level of histone gene mRNA during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of one or more histone RNAs measured in a cell is higher than normal (i.e. lower than observed in wild-type cells) during S phase of the mitotic cell cycle. Histone RNAs are transcribed from genes encoding histones. FYPO_relaxed.owl FYPO:0006423 biolink:NamedThing decreased meiotic sister chromatid cohesion at centromere during meiosis I A cellular process phenotype in which cohesion between sister chromatids is decreased in centromeric regions during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006425 biolink:NamedThing normal meiotic sister chromatid cohesion at centromere during meiosis I A cellular process phenotype in which cohesion between sister chromatids is normal (i.e. indistinguishable from wild type) in centromeric regions during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0006429 biolink:NamedThing normal histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 in subtelomeric regions is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006434 biolink:NamedThing decreased protein localization to medial cortical node, with protein distributed in cell cortex, during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical node of a cell is decreased, and the protein is instead detected distributed throughout the cell cortex. There may be little or no protein detected at the medial cortical node. FYPO_relaxed.owl FYPO:0006446 biolink:NamedThing increased mitochondrial pre-mRNA level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of any unspliced or incompletely spliced mRNA precursor measured in the mitochondrion is higher than normal. FYPO_relaxed.owl FYPO:0006452 biolink:NamedThing decreased histone H3 acetyltransferase processivity A molecular function phenotype in which the observed processivity of a histone H3 acetyltransferase activity is lower than normal. Processivity refers to the number of methylation reactions catalyzed (methyl residues added) per histone binding event. FYPO_relaxed.owl FYPO:0006511 biolink:NamedThing shortened telomeres during G0 A physical cellular phenotype in which cells form telomeres that are shorter than normal during G0 phase. Normally, telomere length is stable in G0, whereas telomere sequences can be lost in mutants. FYPO_relaxed.owl FYPO:0006472 biolink:NamedThing decreased translation of amino acid biosynthesis proteins in response to amino acid starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of translation of one or more proteins involved in amino acid biosynthesis is decreased in response to starvation for one or more amino acids. FYPO_relaxed.owl FYPO:0006473 biolink:NamedThing decreased transcription of amino acid biosynthesis genes in response to amino acid starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription of amino acid biosynthesis genes from RNA polymerase II promoters occurs to a lower extent than normal in response to starvation for one or more amino acids. Amino acid biosynthesis genes are those whose products are involved in amino acid biosynthetic processes. FYPO_relaxed.owl FYPO:0006478 biolink:NamedThing decreased mitotic cohesin dsDNA (leading strand) loading A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin dsDNA (leading strand) loading is decreased during the mitotic cell cycle. Cohesin dsDNA (leading strand) loading is the topological linking of a cohesin ring complex to double-stranded DNA, i.e. the leading strand, in chromatin. FYPO_relaxed.owl FYPO:0006483 biolink:NamedThing decreased mitotic cohesin ssDNA (lagging strand) loading A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin ssDNA (lagging strand) loading is decreased during the mitotic cell cycle. Cohesin ssDNA (lagging strand) loading is the topological linking of a cohesin ring complex to single-stranded DNA, i.e. the lagging strand, in chromatin. FYPO_relaxed.owl FYPO:0006484 biolink:NamedThing abolished mitotic cohesin dsDNA (leading strand) loading A cell phenotype observed in the vegetative growth phase of the life cycle in which cohesin dsDNA (leading strand) loading does not occur during the mitotic cell cycle. Cohesin dsDNA (leading strand) loading is the topological linking of a cohesin ring complex to double-stranded DNA of the leading strand in chromatin. FYPO_relaxed.owl FYPO:0006489 biolink:NamedThing normal cellular phosphatidylinositol-3-phosphate level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3-phosphate measured in a cell is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006496 biolink:NamedThing normal plasma membrane phosphatidylserine distribution A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of phosphatidylserine in the plasma membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006497 biolink:NamedThing abnormal plasma membrane phosphatidylserine distribution A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of phosphatidylserine in the plasma membrane is abnormal. FYPO_relaxed.owl FYPO:0007414 biolink:NamedThing subtelomere expansion during G0 A physical cellular phenotype in which a subtelomeric region (STE1) adjacent to telomeric repeats is duplicated by homologous recombination. FYPO_relaxed.owl FYPO:0006518 biolink:NamedThing loss of viability in G0 A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable after entering G0 phase. FYPO_relaxed.owl FYPO:0006660 biolink:NamedThing loss of viability upon G0 to G1 transition A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable upon exiting G0 phase. FYPO_relaxed.owl FYPO:0006543 biolink:NamedThing increased protein level during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during metaphase of mitosis is higher than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0006547 biolink:NamedThing abnormal plasma membrane phosphatidylserine distribution resulting in decreased concentration at cell tip A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of phosphatidylserine (PS) in the plasma membrane is abnormal such that the PS level is lower than normal at one or both cell tips. Normally, PS shows a polarized distribution with a higher concentration at the cell tips than in the lateral plasma membrane. FYPO_relaxed.owl FYPO:0006564 biolink:NamedThing sensitive to ethanol in stationary phase A phenotype in which cells show increased sensitivity to ethanol when the cell population is in stationary phase. Cells stop growing (and may die) at a concentration of ethanol that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0008001 biolink:NamedThing sensitive to menadione in stationary phase A phenotype in which cells show increased sensitivity to menadione when the cell population is in stationary phase. Cells stop growing (and may die) at a concentration of menadione that allows wild type cells to grow. FYPO_relaxed.owl FYPO:0006571 biolink:NamedThing increased cyclin-dependent protein kinase activity during cellular response to pheromone A molecular function phenotype in which the observed rate of a cyclin-dependent protein kinase activity is increased during a cellular response to a pheromone. FYPO_relaxed.owl FYPO:0006767 biolink:NamedThing increased cyclin-dependent protein kinase activity in absence of meiotic DNA replication checkpoint arrest A molecular function phenotype in which the observed rate of a cyclin-dependent protein kinase activity is increased during the meiotic cell cycle, in cells that have not arrested the meiotic cell cycle under conditions that normally trigger meiotic DNA replication checkpoint signaling and response. FYPO_relaxed.owl FYPO:0006583 biolink:NamedThing decreased protein localization to nuclear periphery during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear periphery is decreased during interphase of the mitotic cell cycle. The nuclear periphery is the portion of the nuclear lumen proximal to the inner nuclear membrane. FYPO_relaxed.owl FYPO:0006586 biolink:NamedThing abolished protein localization to shmoo tip membrane, with protein distributed in plasma membrane A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is abolished, and the protein is instead detected distributed over a greater area of the plasma membrane than normal. FYPO_relaxed.owl FYPO:0006587 biolink:NamedThing decreased protein localization to shmoo tip membrane A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is decreased. FYPO_relaxed.owl FYPO:0006589 biolink:NamedThing decreased protein localization to shmoo tip membrane, with protein distributed in plasma membrane A cell phenotype in which the localization of a protein to the plasma membrane at the tip of a shmoo, or mating projection, is decreased, and some of the protein is instead detected distributed over a greater area of the plasma membrane than normal. FYPO_relaxed.owl FYPO:0006593 biolink:NamedThing decreased mitotic spindle microtubule nucleation from spindle pole body A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which nucleation of spindle microtubules from the spindle pole body (SPB) occurs to a lesser extent than normal. FYPO_relaxed.owl FYPO:0006602 biolink:NamedThing decreased replication fork arrest at MPS1 barrier A cellular process phenotype observed in the vegetative growth phase of the life cycle in which replication fork arrest at the MPS1 barrier in the mating-type locus occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0006608 biolink:NamedThing intermittent protein localization to Cdr2 medial cortical node complex decoupled from cell size A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein that is normally localized intermittently to the Cdr2 medial cortical node complex shows a pattern of localization to the complex over time that is not correlated with cell size as normal. FYPO_relaxed.owl FYPO:0006609 biolink:NamedThing decreased protein dwell time during intermittent localization to Cdr2 medial cortical node complex A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein that is normally localized intermittently to the Cdr2 medial cortical node complex is associated with the complex for periods of shorter duration than normal. FYPO_relaxed.owl FYPO:0006610 biolink:NamedThing increased protein dwell time during intermittent localization to Cdr2 medial cortical node complex A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein that is normally localized intermittently to the Cdr2 medial cortical node complex is associated with the complex for periods of longer duration than normal. FYPO_relaxed.owl FYPO:0006611 biolink:NamedThing decreased frequency of protein localization to Cdr2 medial cortical node complex during intermittent localization to Cdr2 medial cortical node complex A cellular process phenotype observed in the vegetative growth phase of the life cycle in which a protein that is normally localized intermittently to the Cdr2 medial cortical node complex is associated with the complex less frequently than normal. FYPO_relaxed.owl FYPO:0006623 biolink:NamedThing decreased phosphatidylinositol-3,4,5-trisphosphate level in plasma membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-3,4,5-trisphosphate measured in the plasma membrane is lower than normal. FYPO_relaxed.owl FYPO:0006625 biolink:NamedThing decreased phosphatidylinositol-4,5-bisphosphate level in plasma membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4,5-bisphosphate measured in the plasma membrane is lower than normal. FYPO_relaxed.owl FYPO:0006628 biolink:NamedThing decreased phosphatidylinositol-4-phosphate level in plasma membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of phosphatidylinositol-4-phosphate measured in the plasma membrane is lower than normal. FYPO_relaxed.owl FYPO:0006644 biolink:NamedThing decreased protein localization to mitotic spindle midzone, with protein distributed along spindle, during anaphase B A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle midzone is decreased, and some of the protein is present along the entire length of the spindle, during anaphase B of mitosis. FYPO_relaxed.owl FYPO:0006646 biolink:NamedThing normal duration of mitotic prometaphase A cell cycle phenotype in which the duration of prometaphase of mitosis normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006657 biolink:NamedThing abolished acid phosphatase activity during cellular response to phosphate starvation A molecular function phenotype in which acid phosphatase activity is absent during a cellular response to phosphate starvation. FYPO_relaxed.owl FYPO:0006658 biolink:NamedThing decreased acid phosphatase activity during cellular response to phosphate starvation A molecular function phenotype in which the observed rate of acid phosphatase activity is decreased during a cellular response to phosphate starvation. FYPO_relaxed.owl FYPO:0006665 biolink:NamedThing increased nucleophagy during G0 A cellular process phenotype in which autophagy of the nucleus occurs to a greater extent than normal during G0 phase. FYPO_relaxed.owl FYPO:0008086 biolink:NamedThing abolished nucleophagy during nitrogen starvation A cellular process phenotype in which autophagic degradation of the nucleus during nitrogen starvation is abolished . FYPO_relaxed.owl FYPO:0008087 biolink:NamedThing decreased nucleophagy during nitrogen starvation A cellular process phenotype in which autophagic degradation of the nucleus during nitrogen starvation is decreased. FYPO_relaxed.owl FYPO:0009003 biolink:NamedThing abolished nuclear fusion with normal nuclear congression during mating A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion does not occur, despite the nuclei and their SPBs coming together. FYPO_relaxed.owl FYPO:0006687 biolink:NamedThing decreased DNA double-strand break processing during double-strand break repair via homologous recombination A cellular process phenotype in which DNA double-strand break resection that occurs as part of double-strand break repair via homologous recombination is decreased. DNA double-strand break resection is the process by which long-tract single-stranded 3'-end DNA is generated by removal of bases from a 5' end from which SPO11/Rec12-oligonucleotide complexes have been removed. FYPO_relaxed.owl FYPO:0006688 biolink:NamedThing increased transversion frequency A cell phenotype observed in the vegetative growth phase of the life cycle in which transversion mutations occur at a higher frequency than normal. FYPO_relaxed.owl FYPO:0006689 biolink:NamedThing increased insertion/deletion frequency A cell phenotype observed in the vegetative growth phase of the life cycle in which insertion or deletion mutations occur at a higher frequency than normal. FYPO_relaxed.owl FYPO:0006709 biolink:NamedThing abolished protein phosphorylation during cellular response to salt stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the phosphorylation of one or more specific proteins, or of specific protein sites, does not occur during a cellular response to salt stress. FYPO_relaxed.owl FYPO:0006739 biolink:NamedThing normal protein localization to chromatin at MCB promoters during vegetative growth A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006747 biolink:NamedThing asymmetric mitochondrial aggregation at old end An abnormal intracellular mitochondrion distribution phenotype observed in the vegetative growth phase of the life cycle in which mitochondria cluster together more than normal, distal to the side of the nucleus near the old cell end. FYPO_relaxed.owl FYPO:0006750 biolink:NamedThing normal pre-tRNA level during nitrogen starvation A cell phenotype in which the amount of one or more transfer RNA precursor(s) (pre-tRNA) measured in a cell that is subject to nitrogen starvation is normal (i.e. indistinguishable from wild type). Total pre-tRNA or a specific pre-tRNA may be affected. FYPO_relaxed.owl FYPO:0006788 biolink:NamedThing decreased poly(A)-specific ribonuclease activity A molecular function phenotype in which the observed rate of poly(A)-specific ribonuclease activity is decreased. FYPO_relaxed.owl FYPO:0006789 biolink:NamedThing normal poly(A)-specific ribonuclease activity A molecular function phenotype in which the observed rate of poly(A)-specific ribonuclease activity is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006807 biolink:NamedThing decreased galactose level in cell surface glycoprotein glycan A phenotype in which the glycan moiety of a glycoprotein found at the cell surface contains a lower amount of galactose residues than normal. In wild-type cells, glycoprotein glycans contain mannose and galactose residues in a 1:1.2 ratio, and the galactose residues are connected by alpha-1,2 linkages. FYPO_relaxed.owl FYPO:0006814 biolink:NamedThing increased histone H3-K9 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 9 of histone H3 in centromere outer repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0006822 biolink:NamedThing viable small vegetative cell with normal cell growth rate A cell morphology phenotype in which a vegetatively growing cell is viable and elongates at a normal rate, but divides when a shorter time than normal has elapsed since the previous cell division. Daughter cells therefore have an abnormally low volume. Note that these small viable cells result from a cell cycle size regulation defect. FYPO_relaxed.owl FYPO:0006823 biolink:NamedThing viable small vegetative cell with slow cell growth A cell morphology phenotype in which a vegetatively growing cell is viable, but elongates at a slower rate than normal and divides with an abnormally low volume. FYPO_relaxed.owl FYPO:0006838 biolink:NamedThing abnormal linear element maturation A cellular process phenotype in which linear element maturation is abnormal. Linear element maturation is the close association of assembled LinE complexes with chromatin during meiotic prophase to form mature linear elements. FYPO_relaxed.owl FYPO:0006850 biolink:NamedThing abnormal cell cycle arrest at mitotic G2/M phase transition following single cell division during nitrogen starvation A cellular process phenotype in which progression through the mitotic cell cycle is arrested at the mitotic G2/M phase transition, instead of the normal G1 phase, and after the cell undergoes one cell division instead of the normal two, when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0006856 biolink:NamedThing increased histone H3-K37 methylation A cellular process phenotype in which methylation of lysine at position 37 of histone H3 is increased. FYPO_relaxed.owl FYPO:0006857 biolink:NamedThing decreased histone H3-K37 methylation A cellular process phenotype in which methylation of lysine at position 37 of histone H3 is decreased. FYPO_relaxed.owl FYPO:0006858 biolink:NamedThing abolished histone H3-K37 methylation A cellular process phenotype in which methylation of lysine at position 37 of histone H3 does not occur. FYPO_relaxed.owl FYPO:0006874 biolink:NamedThing increased protein localization to cell cortex of old growing cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cell cortex at an old growing cell tip is increased. FYPO_relaxed.owl FYPO:0006882 biolink:NamedThing imperforate nuclear envelope A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the nuclear envelope is imperforate (i.e. has no openings in the membranes, like wild type). FYPO_relaxed.owl FYPO:0006888 biolink:NamedThing normal protein localization to plasma membrane during iron starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the plasma membrane is normal (i.e. indistinguishable from wild type) when the cell is subject to iron ion starvation. FYPO_relaxed.owl FYPO:0006898 biolink:NamedThing normal cell wall thickness during vegetative growth A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the thickness of the cell wall is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006903 biolink:NamedThing decreased total protein level during mitotic S phase A cell phenotype observed in the vegetative growth phase of the life cycle in which the total amount of protein measured in a cell is lower than normal during S phase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0006905 biolink:NamedThing normal mitotic G1 cell size control checkpoint A cell cycle checkpoint phenotype in which a mitotic cell size control checkpoint is normal (i.e. indistinguishable from wild type). A mitotic cell size control checkpoint normally prevents cell cycle progression from G1 to S phase until the cell reaches a certain size. FYPO_relaxed.owl FYPO:0006906 biolink:NamedThing normal mitotic G2 cell size control checkpoint A cell cycle checkpoint phenotype in which a mitotic cell size control checkpoint is normal (i.e. indistinguishable from wild type). A mitotic cell size control checkpoint normally prevents cell cycle progression from G2 to M phase until the cell reaches a certain size. FYPO_relaxed.owl FYPO:0006907 biolink:NamedThing normal mitotic G1 cell size control checkpoint following nitrogen starvation-induced arrest in G1 phase A cell cycle checkpoint phenotype in which a mitotic cell size control checkpoint is normal (i.e. indistinguishable from wild type) when the cell re-enters the mitotic cell cycle following nitrogen starvation-induced arrest in G1 phase. A mitotic cell size control checkpoint normally prevents cell cycle progression from G1 to S phase until the cell reaches a certain size. FYPO_relaxed.owl FYPO:0006908 biolink:NamedThing normal mitotic G1 cell size control checkpoint following spore germination A cell cycle checkpoint phenotype in which a mitotic cell size control checkpoint is normal (i.e. indistinguishable from wild type) in the cell cycle following spore germination. A mitotic cell size control checkpoint normally prevents cell cycle progression from G1 to S phase until the cell reaches a certain size. FYPO_relaxed.owl FYPO:0006921 biolink:NamedThing decreased gene conversion at mitotic DNA replication fork barriers A cellular process phenotype in which the frequency of gene conversion at replication fork barriers is decreased. FYPO_relaxed.owl FYPO:0006938 biolink:NamedThing actin cables present in increased numbers during cytokinesis A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more actin cables than normal during cytokinesis. FYPO_relaxed.owl FYPO:0006984 biolink:NamedThing increased transcriptional readthrough at RNA polymerase III-transcribed genes A phenotype in which a transcript synthesized on a DNA template by RNA polymerase III is longer than normal due to transcription beyond the normal termination site. FYPO_relaxed.owl FYPO:0006992 biolink:NamedThing normal chromatin silencing at centromere otr1R A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the right outer repeat region (otr1R) of the centromere is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0006993 biolink:NamedThing decreased chromatin silencing at centromere otr1R A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere outer repeat regions is decreased at the right outer repeat region (otr1R) of the centromere. FYPO_relaxed.owl FYPO:0006994 biolink:NamedThing increased chromatin silencing at centromere otr1L A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at centromere outer repeat regions is increased at the left outer repeat region (otr1L) of the centromere. FYPO_relaxed.owl FYPO:0006997 biolink:NamedThing decreased histone turnover at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a lower extent than normal at the silent mating-type cassette. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. FYPO_relaxed.owl FYPO:0006998 biolink:NamedThing decreased histone turnover at transposable element during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a lower extent than normal at transposable elements. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. FYPO_relaxed.owl FYPO:0007004 biolink:NamedThing decreased histone turnover at protein coding gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a lower extent than normal in regions containing protein coding genes. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. FYPO_relaxed.owl FYPO:0007473 biolink:NamedThing decreased histone turnover during G0 A cellular process phenotype in which histone exchange is abnormal during G0 phase. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. FYPO_relaxed.owl FYPO:0007892 biolink:NamedThing increased histone turnover at subtelomeric heterochromatin A cellular process phenotype in which histone exchange at subtelomeric heterochromatin is increased. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. FYPO_relaxed.owl FYPO:0007000 biolink:NamedThing normal histone exchange at transposable element A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a normal (i.e. indistinguishable from wild type) extent at transposable elements. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. FYPO_relaxed.owl FYPO:0007001 biolink:NamedThing normal histone exchange at pericentric heterochromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a normal (i.e. indistinguishable from wild type) extent in regions of pericentric heterochromatin. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. FYPO_relaxed.owl FYPO:0007002 biolink:NamedThing normal histone exchange at silent mating-type cassette A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a normal (i.e. indistinguishable from wild type) extent at the silent mating-type cassette. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. FYPO_relaxed.owl FYPO:0007003 biolink:NamedThing normal histone exchange at tRNA genes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which histone exchange occurs to a normal (i.e. indistinguishable from wild type) extent at tRNA genes. Histone exchange is replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits. FYPO_relaxed.owl FYPO:0007708 biolink:NamedThing normal dynamic protein localization to cell tip A cell phenotype in which a protein that is normally dynamically localized to one or both cell tips shows a normal (i.e. indistinguishable from wild type) temporal pattern of localization. For example, a protein may move from one cell tip to the other at a normal frequency and amplitude. FYPO_relaxed.owl FYPO:0007009 biolink:NamedThing decreased heterochromatin assembly by small RNA A cellular process phenotype observed in the vegetative growth phase of the life cycle in which assembly of heterochromatin mediated by small RNA is decreased. FYPO_relaxed.owl FYPO:0007010 biolink:NamedThing secondary siRNA absent from cell A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of secondary siRNA measured in a cell is too low to detect. Secondary siRNAs are sequences homologous to regions 5' and 3' to the initial siRNA, and their production amplifies the primary siRNA signal. FYPO_relaxed.owl FYPO:0007015 biolink:NamedThing increased protein localization to chromatin at 3' end of tRNA genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at the 3' ends of tRNA genes is increased. FYPO_relaxed.owl FYPO:0007734 biolink:NamedThing increased protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin at the 3' ends of genes that can be transcribed by RNA polymerase III is increased. FYPO_relaxed.owl FYPO:0007735 biolink:NamedThing increased protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin at the 3' ends of genes that can be transcribed by RNA polymerase III is increased during metaphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007736 biolink:NamedThing protein displaced from 3' end to 5' end of RNA polymerase II-transcribed genes during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is altered such that more of the protein is present at the 5' end, and less at the 3' end, than normal during metaphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007995 biolink:NamedThing abolished protein localization to old cell tip during mitotic interphase A cell phenotype in which the localization of a protein to the old cell tip does not occur during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007039 biolink:NamedThing decreased protein localization to mitochondrion, with protein mislocalized to cytoplasmic foci A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion is decreased, and the protein is instead visible in one or a few foci or dots in the cytoplasm. FYPO_relaxed.owl FYPO:0007601 biolink:NamedThing decreased protein localization to mitochondrion, with diffuse cytoplasmic protein mislocalization A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitochondrion is decreased, and the protein is instead visible diffusely localized in the cytoplasm. FYPO_relaxed.owl FYPO:0007044 biolink:NamedThing decreased alkaline phosphatase activity during stress response to zinc ion A molecular function phenotype in which the observed rate of alkaline phosphatase activity is decreased during a cellular stress response to zinc ions. FYPO_relaxed.owl FYPO:0007045 biolink:NamedThing decreased alkaline phosphatase activity during cellular response to zinc ion starvation A molecular function phenotype in which the observed rate of alkaline phosphatase activity is decreased during a cellular response to zinc ion starvation. FYPO_relaxed.owl FYPO:0007046 biolink:NamedThing abolished alkaline phosphatase activity during cellular response to zinc ion starvation A molecular function phenotype in which alkaline phosphatase activity is absent during a cellular response to zinc ion starvation. FYPO_relaxed.owl FYPO:0007048 biolink:NamedThing normal alkaline phosphatase activity during stress response to zinc ion A molecular function phenotype in which the observed rate of alkaline phosphatase activity is normal (i.e. indistinguishable from wild type) during a cellular stress response to zinc ions. FYPO_relaxed.owl FYPO:0007049 biolink:NamedThing decreased RNA level during stress response to zinc ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular stress response to zinc ions is lower than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0007050 biolink:NamedThing increased RNA level during stress response to zinc ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of RNA measured in a cell during a cellular stress response to zinc ions is higher than normal. Total RNA or a specific RNA may be affected. FYPO_relaxed.owl FYPO:0007051 biolink:NamedThing altered protein level during stress response to zinc ion A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell differs from normal during a cellular stress response to zinc ions. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007059 biolink:NamedThing decreased protein localization to late endosome A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to late endosomes is decreased. FYPO_relaxed.owl FYPO:0007588 biolink:NamedThing abolished protein localization to late endosome A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to late endosomes does not occur. FYPO_relaxed.owl FYPO:0007068 biolink:NamedThing increased origin firing efficiency in subtelomeric heterochromatin A regulation phenotype observed in the vegetative growth phase of the life cycle in which the probability that a DNA replication will initiate at a particular replication origin located in heterochromatin at subtelomeric regions is higher than in wild type. In cells with increased origin firing efficiency, genomic DNA replication initiates from more origins than wild type, and is completed in more, smaller segments, than wild type. FYPO_relaxed.owl FYPO:0007087 biolink:NamedThing abolished sporulation during sulfur starvation A cellular process phenotype in which ascospore formation does not occur when cells are subject to sulfur starvation. FYPO_relaxed.owl FYPO:0007092 biolink:NamedThing increased DNA binding during cellular response to zinc ion A molecular function phenotype in which occurrence of DNA binding by a gene product is increased during a cellular response to zinc ions, when a gene or the bound DNA sequence is mutated. The affected gene product may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007095 biolink:NamedThing increased protein localization to actin fusion focus A cell phenotype in which the localization of a protein to the actin fusion focus is increased. FYPO_relaxed.owl FYPO:0007096 biolink:NamedThing decreased protein localization to actin fusion focus A cell phenotype in which the localization of a protein to the actin fusion focus is decreased. FYPO_relaxed.owl FYPO:0007102 biolink:NamedThing multiple spindles during meiosis II A physical cellular phenotype in which a cell contains more than one meiotic spindle per nucleus during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0007753 biolink:NamedThing multiple spindles during meiosis I A physical cellular phenotype in which a cell contains more than one meiotic spindle during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007103 biolink:NamedThing spindle collapse during meiosis I A cell phenotype in which a short meiotic spindle assembles during meiosis I, and may begin elongation, but does not elongate normally or completely, and eventually collapses. Upon collapse the spindle may break or shrink. FYPO_relaxed.owl FYPO:0007110 biolink:NamedThing microtubule bundles present in decreased numbers at spindle pole body during meiosis I A physical cellular phenotype in which cells contain fewer microtubule bundles associated with the spindle pole body than normal during meiosis I. FYPO_relaxed.owl FYPO:0009058 biolink:NamedThing decreased microtubule depolymerisation involved in meitotic centromere clustering during meiotic prophase I A cellular process in which depolymerization (i.e. removal of tubulin dimers) of microtubules as part of centromere clustering during meiotic prophase I is decreased with respect to normal. This can happen due to lower catastrophe rate or depolymerisation speed. FYPO_relaxed.owl FYPO:0009057 biolink:NamedThing decreased rate of microtubule catastrophe involved in meitotic centromere clustering during meiotic prophase I A cellular process in which catastrophe rate (i.e. the frequency of transition from pause or growth to shrinkage) of microtubules is lower than normal as part of centromere clustering during meiotic prophase I. FYPO_relaxed.owl FYPO:0007115 biolink:NamedThing abolished protein localization to medial cortical node, with protein mislocalized to cytoplasm during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the medial cortical nodes is abolished, and the protein is present in the cytoplasm instead, during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007621 biolink:NamedThing increased protein-protein interaction during cellular response to oxidative stress A molecular function phenotype in which the binding of one protein to another occurs to a lower extent than normal when the cell is subject to oxidative stress. The relevant proteins may include the one encoded by the mutated gene, or may both be encoded by different genes. FYPO_relaxed.owl FYPO:0007798 biolink:NamedThing increased actin filament binding A molecular function phenotype in which the binding of a protein to one or more actin filaments occurs to a greater extent than normal. The affected protein may be encoded by the mutated gene, or by a different gene. FYPO_relaxed.owl FYPO:0007145 biolink:NamedThing normal 5' deoxyribonuclease (pyrimidine dimer) activity during cellular response to UV A molecular function phenotype in which the observed rate of 5' deoxyribonuclease (pyrimidine dimer) activity is normal (i.e. indistinguishable from wild type) during a cellular response to ultraviolet light. FYPO_relaxed.owl FYPO:0007166 biolink:NamedThing abolished protein localization to cell cortex during meiotic prophase I A cell phenotype in which the localization of a protein to the cell cortex does not occur during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007179 biolink:NamedThing mislocalized protein distributed in cell cortex during mitotic interphase A cell phenotype in which a protein is detected abnormally distributed throughout the cell cortex during interphase of the mitotic cell cycle. The protein may normally be restricted to part of the cell cortex, or not normally located in the cell cortex at all. FYPO_relaxed.owl FYPO:0007180 biolink:NamedThing mislocalized protein distributed in cell cortex during mitosis A cell phenotype in which a protein is detected abnormally distributed throughout the cell cortex during mitosis. The protein may normally be restricted to part of the cell cortex, or not normally located in the cell cortex at all. FYPO_relaxed.owl FYPO:0007198 biolink:NamedThing normal mitotic centromeric sister chromatid cohesion A cellular process phenotype in which cohesion between centromeres of sister chromatids is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007200 biolink:NamedThing aggregated actin cortical patches during mitotic interphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which actin cortical patches cluster together more than normal during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007201 biolink:NamedThing decreased rate of actin cortical patch localization to cell division site A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate, or speed, of actin cortical patch localization to the site of cell division is decreased. FYPO_relaxed.owl FYPO:0007216 biolink:NamedThing abolished protein localization to chromatin at MCB promoters during cellular response to hydroxyurea A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at promoters that contain MCB sites is abolished during a cellular response to hydroxyurea. FYPO_relaxed.owl FYPO:0007236 biolink:NamedThing delayed onset of protein localization to chromatin at early replication origin A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to chromatin at early replication origins (i.e. origins that normally fire early in S phase) begins later than normal. FYPO_relaxed.owl FYPO:0007239 biolink:NamedThing normal protein localization to old growing cell tip A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the old growing cell tip is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007241 biolink:NamedThing abolished NETO in cell derived from growing end and premature NETO in cell derived from non-growing end A cell polarity phenotype in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) is abnormal in both of the daughter cells formed as a result of the division of a mother cell in which NETO did not occur, such that NETO is abolished in the daughter cell that inherits the parent cell's old end, and begins earlier than normal in the daughter cell that inherits parent cell's new end. Normally, growth begins at the old end and then becomes bipolar with similar timing in both daughter cells. FYPO_relaxed.owl FYPO:0007242 biolink:NamedThing abolished NETO in both daughter cells A cell polarity phenotype in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) is abolished in both of the daughter cells formed as a result of the division of a mother cell in which NETO did not occur. Normally, growth begins at the old end and then becomes bipolar with similar timing in both daughter cells. FYPO_relaxed.owl FYPO:0007243 biolink:NamedThing normal NETO in cell derived from growing end and premature NETO in cell derived from non-growing end A cell polarity phenotype in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) is normal (i.e. indistinguishable from wild type) in one, and premature in the other, of the daughter cells formed as a result of the division of a mother cell in which NETO did not occurs. NETO is normal in the daughter cell that inherits the parent cell's old end, and begins earlier than normal in the daughter cell that inherits parent cell's new end. Normally, growth begins at the old end and then becomes bipolar with similar timing in both daughter cells. FYPO_relaxed.owl FYPO:0007247 biolink:NamedThing abolished mitotic G2 DNA damage checkpoint during cellular response to ionizing radiation A cell cycle checkpoint phenotype in which cell cycle regulation mediated by the mitotic G2 DNA damage checkpoint does not occur during a cellular response to ionizing radiation. Normally, the mitotic G2 DNA damage checkpoint negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage. FYPO_relaxed.owl FYPO:0007501 biolink:NamedThing abnormal horsetail-astral microtubule organization A cellular process phenotype in which assembly, arrangement of constituent parts, or disassembly of the horsetail-astral microtubule array is abnormal. FYPO_relaxed.owl FYPO:0007259 biolink:NamedThing increased meiotic spindle pole body duplication A cellular process phenotype in which the occurrence of meiotic spindle pole body duplication is increased. FYPO_relaxed.owl FYPO:0007483 biolink:NamedThing abnormal meiotic spindle pole body duplication during meiosis I A cellular process phenotype in which meiotic spindle pole body duplication is abnormal during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007261 biolink:NamedThing decreased telomere tethering at nuclear periphery during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere tethering at the nuclear periphery is decreased. FYPO_relaxed.owl FYPO:0007770 biolink:NamedThing increased telomere tethering at nuclear periphery during mitosis A cellular process phenotype observed in the vegetative growth phase of the life cycle in which telomere tethering at the nuclear periphery persists after the onset of mitosis. Normally, telomeres are maintained at the nuclear periphery during interphase and released during mitosis. FYPO_relaxed.owl FYPO:0007263 biolink:NamedThing eisosomes present in decreased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer eisosomes than normal. FYPO_relaxed.owl FYPO:0007265 biolink:NamedThing long eisosome filaments present in decreased numbers A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain fewer, and longer, eisosome filaments than normal. FYPO_relaxed.owl FYPO:0007266 biolink:NamedThing decreased colocalization of cortical endoplasmic reticulum with eisosomes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the endoplasmic reticulum (ER) colocalizes with eisosomes to a lower extent than normal. FYPO_relaxed.owl FYPO:0007267 biolink:NamedThing increased colocalization of cortical endoplasmic reticulum with eisosomes A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the endoplasmic reticulum (ER) colocalizes with eisosomes to a greater extent than normal. FYPO_relaxed.owl FYPO:0007268 biolink:NamedThing decreased cortical endoplasmic reticulum remodeling A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cortical endoplasmic reticulum (ER) remodeling occurs to a lower extent than normal. Cortical ER remodeling is the dynamic spatial rearrangement of ER tubules near the cell cortex. FYPO_relaxed.owl FYPO:0007273 biolink:NamedThing increased cortical endoplasmic reticulum remodeling A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cortical endoplasmic reticulum (ER) remodeling occurs to a greater extent than normal. Cortical ER remodeling is the dynamic spatial rearrangement of ER tubules near the cell cortex. FYPO_relaxed.owl FYPO:0007286 biolink:NamedThing normal protein localization to late endosome membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the late endosome membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007287 biolink:NamedThing decreased protein galactosylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the galactosylation of one or more specific proteins, or of specific protein sites, occurs to a lower extent than normal. Protein galactosylation is the addition of a galactose residue to a protein amino acid. FYPO_relaxed.owl FYPO:0007299 biolink:NamedThing decreased protein aggregate center formation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein aggregate center formation is decreased. Protein aggregate centers are composed of chaperones and misfolded proteins, and are reversibly formed in the nucleus and cytosol to shield thermosensitive proteins from degradation until conditions allow disaggregation and refolding. FYPO_relaxed.owl FYPO:0007305 biolink:NamedThing increased histone H4-K5 acetylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 5 of histone H4 in centromeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0008172 biolink:NamedThing increased histone H4-K5 acetylation at silent mating-type cassette during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 5 of histone H4 at the silent mating type cassette occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007308 biolink:NamedThing increased histone H4-K5 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 5 of histone H4 in centromere outer repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007309 biolink:NamedThing increased histone H4-K8 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 in centromere outer repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007310 biolink:NamedThing increased histone H4-K12 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 12 of histone H4 in centromere outer repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007311 biolink:NamedThing increased histone H4-K16 acetylation at centromere outer repeat during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 16 of histone H4 in centromere outer repeat regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007314 biolink:NamedThing increased histone H4-K12 acetylation at centromere central core during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 12 of histone H4 at the central core of the centromeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007312 biolink:NamedThing increased histone H4-K5 acetylation at centromere central core during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 5 of histone H4 at the central core of the centromeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007313 biolink:NamedThing increased histone H4-K8 acetylation at centromere central core during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which acetylation of lysine at position 8 of histone H4 at the central core of the centromeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007323 biolink:NamedThing normal stress granule assembly during cellular response to heat A cellular process phenotype observed in the vegetative growth phase of the life cycle in which stress granule assembly is normal (i.e. indistinguishable from wild type) during a cellular response to heat. FYPO_relaxed.owl FYPO:0007326 biolink:NamedThing decreased mitochondrial tRNA 3'-end processing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which mitochondrial tRNA 3'-end processing is decreased. In mitochondrial tRNA 3'-end processing, the 3' end of a mitochondrial pre-tRNA molecule is converted to that of a mature mitochondrial tRNA. FYPO_relaxed.owl FYPO:0007333 biolink:NamedThing abolished chromatin silencing A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing does not occur. Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin or CENP-A-containing chromatin (the latter is found at the centromere central core). FYPO_relaxed.owl FYPO:0007338 biolink:NamedThing increased histone H3-K4 trimethylation at centromere during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 4 of histone H3 in centromeric regions occurs to a greater extent than normal. FYPO_relaxed.owl FYPO:0007341 biolink:NamedThing normal histone H3-K4 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 4 of histone H3 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007347 biolink:NamedThing normal histone H3-K36 trimethylation during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which trimethylation of lysine at position 36 of histone H3 is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007349 biolink:NamedThing decreased homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 1 A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased (i.e. occurs to a lower extent) at a cis-acting homologous chromosome pairing region on chromosome 1. FYPO_relaxed.owl FYPO:0007350 biolink:NamedThing decreased homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 2 A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased (i.e. occurs to a lower extent) at a cis-acting homologous chromosome pairing region on chromosome 2. FYPO_relaxed.owl FYPO:0007351 biolink:NamedThing decreased homologous chromosome pairing at cis-acting homologous chromosome pairing region on chromosome 3 A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased (i.e. occurs to a lower extent) at a cis-acting homologous chromosome pairing region on chromosome 3. FYPO_relaxed.owl FYPO:0007366 biolink:NamedThing decreased cellular 2,3-bisphosphoglyceric acid level A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of 2,3-bisphosphoglyceric acid measured in the cell is lower than normal. FYPO_relaxed.owl FYPO:0007376 biolink:NamedThing abolished epigenetic heterochromatin inheritance A phenotype in which a region of the genome that is normally stably assembled and maintained as heterochromatin over successive generations entirely loses heterochromatic structure. FYPO_relaxed.owl FYPO:0007478 biolink:NamedThing decreased epigenetic heterochromatin inheritance A phenotype in which a region of the genome that is normally stably assembled and maintained as heterochromatin over successive generations retains heterochromatic structure for fewer generations than normal. FYPO_relaxed.owl FYPO:0007377 biolink:NamedThing protein mislocalized to medial cortex during mitotic interphase A cell phenotype observed in the vegetative growth phase of the life cycle in which a protein that is not normally found at the medial cortex is observed there during interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007384 biolink:NamedThing normal protein distribution along RNA polymerase II-transcribed genes during cellular response to oxidative stress A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is normal (i.e. indistinguishable from wild type) during a cellular response to oxidative stress. FYPO_relaxed.owl FYPO:0007730 biolink:NamedThing normal protein distribution along RNA polymerase II-transcribed genes during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is normal (i.e. indistinguishable from wild type) during metaphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007387 biolink:NamedThing abolished NETO, with growth from new end A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the switch from the monopolar to bipolar mode of cell growth (new end take-off; NETO) does not occur, and the cell grows only from the new end. FYPO_relaxed.owl FYPO:0007393 biolink:NamedThing septum mislocalized to cell tip A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which a cell has a septum with both ends at the cell tip(s). The normal location is at the midpoint of the long axis of the cell. FYPO_relaxed.owl FYPO:0007404 biolink:NamedThing decreased protein degradation during mitotic anaphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of protein degradation is decreased during anaphase of mitosis. FYPO_relaxed.owl FYPO:0007409 biolink:NamedThing abnormal mRNA alternative polyadenylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which alternative polyadenylation of mRNA is abnormal. mRNA alternative polyadenylation generates mRNA molecules with variable 3'-end lengths from a given pre-mRNA by differential use of cleavage and polyadenylation signals. Includes differences in the relative usage levels of alternative polyadenylation sites. FYPO_relaxed.owl FYPO:0007920 biolink:NamedThing decreased ncRNA alternative polyadenylation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which alternative polyadenylation of ncRNA is decreased. ncRNA alternative polyadenylation generates RNA molecules with variable 3'-end lengths from a given RNA by differential use of cleavage and polyadenylation signals. Includes differences in the relative usage levels of alternative polyadenylation sites. FYPO_relaxed.owl FYPO:0007423 biolink:NamedThing decreased isochromosome formation A cell phenotype in which isochromosome formation occurs less frequently than in wild type cells. In isochromosome formation, one chromosome arm is lost and the other arm is duplicated in its place. FYPO_relaxed.owl FYPO:0007427 biolink:NamedThing abnormal old mitotic spindle pole body insertion into nuclear envelope, with spindle pole body in nucleoplasm A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the insertion of the old spindle pole body (SPB) into the nuclear envelope is abnormal, and the SPB enters the nucleus. The old SPB may be transiently inserted into the nuclear envelope but does not remain in place as normal. FYPO_relaxed.owl FYPO:0007434 biolink:NamedThing attenuated change in cell size at division upon shift to poor nitrogen source A cell phenotype observed in the vegetative growth phase of the life cycle in which cells do not change the length at which they divide to the same extent as normal upon shifting from a good nitrogen source to a poor nitrogen source. Normally, cells divide at a smaller size after shifting to a poor nitrogen source; in mutants the size difference is less pronounced between media with good versus poor nitrogen sources. Good (or rich) nitrogen sources are distinguished from poor sources based on how readily nitrogen is assimilated into cellular metabolism. In microorganisms, good nitrogen sources generally support higher cell population growth rates than poor sources. In fission yeast, cells divide at a smaller size when grown on a poor nitrogen source than in nitrogen-rich media; proline is commonly used as a poor nitrogen source. FYPO_relaxed.owl FYPO:0007442 biolink:NamedThing normal protein localization to endoplasmic reticulum membrane A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the endoplasmic reticulum membrane is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008103 biolink:NamedThing normal protein localization to perinuclear endoplasmic reticulum A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the preinuclear endoplasmic reticulum is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008104 biolink:NamedThing normal protein localization to cortical endoplasmic reticulum A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the cortical endoplasmic reticulum is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008084 biolink:NamedThing abolished reticulophagy during nitrogen starvation A cellular process phenotype in which autophagic degradation of the endoplasmic reticulum is abolished during nitrogen starvation. FYPO_relaxed.owl FYPO:0007446 biolink:NamedThing decreased reticulophagy during cellular response to endoplasmic reticulum stress A cellular process phenotype observed in the vegetative growth phase of the life cycle in which autophagic degradation of the endoplasmic reticulum occurs to a lower extent than normal during a cellular response to endoplasmic reticulum stress. FYPO_relaxed.owl FYPO:0008197 biolink:NamedThing decreased reticulophagy during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which autophagic degradation of the endoplasmic reticulum occurs to a lower extent than normal. FYPO_relaxed.owl FYPO:0007457 biolink:NamedThing excess nuclear envelope present during mitotic interphase A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells contain more nuclear envelope than normal during interphase of the mitotic cell cycle. Excess nuclear envelopes may take the form of intranuclear membrane stacks or invaginations, or small cytoplasmic spheres that are attached to the nucleus, have double lipid bilayer membranes, and may contain structures resembling nuclear pores. FYPO_relaxed.owl FYPO:0007458 biolink:NamedThing abolished nuclear pore localization to mitotic nuclear bridge A localization phenotype observed in the vegetative growth phase of the life cycle in which nuclear pore localization to the portion of the nuclear envelope enclosing the mitotic nuclear bridge does not occur. The nuclear bridge is a narrow constricted region of the nucleus that forms around the mitotic spindle during anaphase. Normally, nuclear pores that lack baskets are found in the midzone of the nuclear bridge. FYPO_relaxed.owl FYPO:0007547 biolink:NamedThing abnormal nuclear pore localization to mitotic nuclear bridge midzone membrane A localization phenotype observed in the vegetative growth phase of the life cycle in which nuclear pore localization to the portion of the nuclear envelope enclosing the mitotic nuclear bridge is abnormal, resulting in an abnormal distribution of nuclear pores in the bridge envelope. The nuclear bridge is a narrow constricted region of the nucleus that forms around the mitotic spindle during anaphase. Normally, nuclear pores that lack baskets are found in the midzone of the nuclear bridge. FYPO_relaxed.owl FYPO:0007460 biolink:NamedThing abnormal nuclear envelope morphology at mitotic nuclear bridge midzone A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which the size, shape, or structure of the portion of the nuclear envelope enclosing the midzone of the mitotic nuclear bridge is abnormal. The nuclear bridge is a narrow constricted region of the nucleus that forms around the mitotic spindle during anaphase. FYPO_relaxed.owl FYPO:0007640 biolink:NamedThing increased histone H3-K9 dimethylation at rDNA during G0 A cellular process phenotype in which the dimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal at ribosomal DNA during G0 phase. FYPO_relaxed.owl FYPO:0007641 biolink:NamedThing decreased histone H3-K9 methylation during G0 A cellular process phenotype in which the methylation of lysine at position 9 of histone H3 occurs to a lower extent than normal during G0 phase. FYPO_relaxed.owl FYPO:0007468 biolink:NamedThing increased histone H3-K9 dimethylation during G0 A cellular process phenotype in which dimethylation of lysine at position 9 of histone H3 occurs to a greater extent than normal during G0 phase. FYPO_relaxed.owl FYPO:0007469 biolink:NamedThing increased histone H3-K9 trimethylation during G0 A cellular process phenotype in which methylation of lysine at position 9 of histone H3 occurs to a greater extent than normal during G0 phase. FYPO_relaxed.owl FYPO:0007471 biolink:NamedThing abnormal heterochromatin organization during G0 A cellular process phenotype in which any process of heterochromatin organization is abnormal during G0 phase. Heterochromatin organization results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin. FYPO_relaxed.owl FYPO:0007476 biolink:NamedThing decreased duration of cell cycle arrest in mitotic G1 phase A cellular process phenotype in which the duration of an otherwise normal occurrence of cell cycle arrest in mitotic G1 phase is shorter than normal. FYPO_relaxed.owl FYPO:0007795 biolink:NamedThing two cell divisions prior to cell cycle arrest in mitotic G1 phase without nutrient starvation A cellular process phenotype in which progression through the mitotic cell cycle is arrested in G1 phase after the cells have undergone two rounds of cell division under nutrient-replete conditions. This arrest resembles that of wild-type cells under conditions of nitrogen starvation. FYPO_relaxed.owl FYPO:0008066 biolink:NamedThing abolished cell cycle arrest in mitotic G1 phase in response to phosphate starvation A cellular process phenotype in which progression through the mitotic cell cycle is no longer arrested during G1 phase when phosphate is removed. Arrest may either occur under conditions where arrest is not a normal occurrence, or may progress differently from normal under conditions where arrest normally does take place. FYPO_relaxed.owl FYPO:0007480 biolink:NamedThing decreased spatial extent of subtelomeric heterochromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a smaller portion of the subtelomeric region of the chromosome than normal. FYPO_relaxed.owl FYPO:0007891 biolink:NamedThing decreased spatial extent of mating-type region heterochromatin assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which heterochromatin is assembled over a smaller portion of the mating-type region than normal. FYPO_relaxed.owl FYPO:0007850 biolink:NamedThing spindle self-assembly during meiosis II A cellular process phenotype in which microtubules self-assemble into a spindle without the participation of the spindle pole body (SPB) during the second meiotic nuclear division. FYPO_relaxed.owl FYPO:0007493 biolink:NamedThing decreased ascospore wall alpha-glucan level A cell phenotype in which the amount of alpha-D-glucan measured in the spore wall is lower than normal. FYPO_relaxed.owl FYPO:0007496 biolink:NamedThing abolished protein localization to nuclear exosome focus at sme2 locus A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the nuclear exosome focus at the sme2 locus does not occur. Other nuclear exosome foci may form normally. FYPO_relaxed.owl FYPO:0007502 biolink:NamedThing decreased protein localization to meiotic spindle pole body during prophase I A cell phenotype in which the localization of a protein to the meiotic spindle pole body is decreased during prophase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007511 biolink:NamedThing normal mitosis following cell cycle arrest in response to mitotic DNA replication checkpoint A cellular process phenotype in which a cell undergoes normal (i.e. indistinguishable from wild type) mitosis upon release from a following release from a G2/M cell cycle block imposed by activation of the mitotic DNA replication checkpoint. FYPO_relaxed.owl FYPO:0007520 biolink:NamedThing normal growth on beta-glucanase A phenotype in which vegetative cell population growth is normal (i.e. indistinguishable from wild type) in a medium containing one or more enzymes that degrades cell wall polysaccharides by hydrolyzing beta-glucan linkages. FYPO_relaxed.owl FYPO:0007529 biolink:NamedThing normal histone H3-K9 dimethylation at heterochromatin island during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the dimethylation of lysine at position 9 of histone H3 at heterochromatin islands is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007531 biolink:NamedThing decreased histone H3-K9 dimethylation at heterochromatin island at meiotic gene during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which dimethylation of lysine at position 9 of histone H3 is decreased at heterochromatin islands near genes that are normally expressed during the meiotic cell cycle. FYPO_relaxed.owl FYPO:0007533 biolink:NamedThing normal replication fork colocalization with nuclear pore complex A cellular process phenotype observed in the vegetative growth phase of the life cycle in which arrested replication forks colocalize normally (i.e. indistinguishably from wild type) with nuclear pore complexes (NPCs). Normally, arrested replication forks relocate to NPCs as part of replication fork processing, and remain anchored at NPCs while recombination-dependent replication takes place. FYPO_relaxed.owl FYPO:0007567 biolink:NamedThing premature protein localization to mitotic spindle pole body during metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body that normally occurs in anaphase instead begins in metaphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007570 biolink:NamedThing septation initiation network signaling from both mitotic spindle pole bodies A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septation initiation network signaling takes place at both mitotic spindle pole bodies. Normally, SIN signaling occurs only at the new SPB. FYPO_relaxed.owl FYPO:0007581 biolink:NamedThing decreased septation initiation network signaling during anaphase B A cellular process phenotype observed in the vegetative growth phase of the life cycle in which septation initiation network signaling occurs to a lower extent than normal during anaphase B of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007582 biolink:NamedThing increased duration of septation initiation network signaling A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the duration of septation initiation network signaling is longer than normal. Signaling may continue after cytokinesis takes place. FYPO_relaxed.owl FYPO:0007585 biolink:NamedThing premature septation initiation network signaling A cell phenotype observed in the vegetative growth phase of the life cycle in which septation initiation network signaling begins earlier than normal. Signaling may begin in interphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007573 biolink:NamedThing premature actomyosin contractile ring contraction with increased contraction rate A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring contraction begins earlier than normal and the rate, or speed, of ring contraction is increased. FYPO_relaxed.owl FYPO:0007579 biolink:NamedThing normal medial membrane band sterol distribution A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in the medial membrane band is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0007580 biolink:NamedThing decreased protein localization to mitotic spindle pole body during anaphase B A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the mitotic spindle pole body is decreased during anaphase B of mitosis. FYPO_relaxed.owl FYPO:0007586 biolink:NamedThing abnormal medial membrane band sterol distribution A localization phenotype observed in the vegetative growth phase of the life cycle in which the distribution of sterols in the medial membrane band is abnormal. FYPO_relaxed.owl FYPO:0007592 biolink:NamedThing normal mitophagy during nitrogen starvation A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, is normal (i.e. indistinguishable from wild type) when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0007594 biolink:NamedThing abolished mitophagy during nitrogen starvation A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, does not occur when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0007595 biolink:NamedThing increased mitophagy during nitrogen starvation A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, is increased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0007596 biolink:NamedThing decreased mitophagy during nitrogen starvation A cellular process phenotype in which mitophagy, i.e. autophagic degradation of the mitochondria, is decreased when the cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0007603 biolink:NamedThing decreased microfilament motor activity A molecular function phenotype in which the observed rate or other property of a microfilament motor activity is decreased. FYPO_relaxed.owl FYPO:0007607 biolink:NamedThing delayed onset of mitotic DNA replication initiation during recovery from nitrogen starvation A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the initiation of nuclear DNA replication begins later than normal when cells are returned to nitrogen-rich medium following nitrogen starvation. FYPO_relaxed.owl FYPO:0007615 biolink:NamedThing increased transcription from STREP promoter during cellular response to nitric oxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which transcription from a promoter that contains one or more STREP motifs occurs to a greater extent than normal during a cellular response to nitric oxide. FYPO_relaxed.owl FYPO:0007623 biolink:NamedThing decreased mitochondrial respiratory chain complex III assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial respiratory chain complex III assembly is decreased. FYPO_relaxed.owl FYPO:0007624 biolink:NamedThing decreased mitochondrial respiratory chain complex IV assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of mitochondrial cytochrome c oxidase (respiratory chain complex IV) assembly is decreased. FYPO_relaxed.owl FYPO:0007626 biolink:NamedThing normal protein oxidation during cellular response to hydrogen peroxide A cellular process phenotype observed in the vegetative growth phase of the life cycle in which protein oxidation is normal (i.e. indistinguishable from wild type) during a cellular response to hydrogen peroxide. FYPO_relaxed.owl FYPO:0007638 biolink:NamedThing decreased anisotropic motion of mitotic chromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the anisotropic movement of chromatin occurs to a lower extent than normal during mitosis. Normally, chromatin moves to a lesser extent, and with less freedom of movement direction (i.e. more anisotropically), during mitosis than during interphase. FYPO_relaxed.owl FYPO:0007642 biolink:NamedThing decreased histone H3-K9 dimethylation at rDNA during G0 A cellular process phenotype in which the dimethylation of lysine at position 9 of histone H3 occurs to a lower extent than normal at ribosomal DNA during G0 phase. FYPO_relaxed.owl FYPO:0007643 biolink:NamedThing decreased histone H3-K9 dimethylation at centromere outer repeat during G0 A cellular process phenotype in which the dimethylation of lysine at position 9 of histone H3 occurs to a lower extent than normal in centromere outer repeat regions during G0 phase. FYPO_relaxed.owl FYPO:0007644 biolink:NamedThing decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during G0 A cellular process phenotype in which the dimethylation of lysine at position 9 of histone H3 occurs to a lower extent than normal in subtelomeric regions occurs during G0 phase. FYPO_relaxed.owl FYPO:0007656 biolink:NamedThing increased nucleosome occupancy at transcription start site A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is higher than normal at transcription start sites. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0008036 biolink:NamedThing increased nucleosome occupancy at CENP-A boundary A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is higher than normal at the CENP-A boundary. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0007657 biolink:NamedThing decreased protein localization to linear element at meiotic recombination hotspot A cell phenotype in which the localization of a protein to linear elements is decreased at one or more meiotic recombination hotspots. FYPO_relaxed.owl FYPO:0007659 biolink:NamedThing variable cell size at division with subsequent division at normal size A cell population phenotype in which cells in a population do not divide at a uniform size, although each cell divides to form equal-size daughter cells, which then subsequently divide at a normal size. Within one population, some cells may be larger and others smaller than normal (i.e. compared to wild-type cells under the same conditions) upon the first division. Daughter cells that are larger than normal upon formation divide earlier, and smaller-formed daughter cells divide later, than cells formed at a normal size. FYPO_relaxed.owl FYPO:0007660 biolink:NamedThing variable cell size at division with subsequent division at abnormal size A cell population phenotype in which cells in a population do not divide at a uniform size, although each cell divides to form equal-size daughter cells, which then subsequently divide at an abnormal size. Within one population, some cells may be larger and others smaller than normal (i.e. compared to wild-type cells under the same conditions) upon each division. FYPO_relaxed.owl FYPO:0007661 biolink:NamedThing normal protein localization to kinetochore during meiotic metaphase I A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during metaphase of meiosis I. FYPO_relaxed.owl FYPO:0007854 biolink:NamedThing normal protein localization to kinetochore during meiotic anaphase I A cell phenotype in which the localization of a protein to the kinetochore of a chromosome is normal (i.e. indistinguishable from wild type) during anaphase of meiosis I. FYPO_relaxed.owl FYPO:0007662 biolink:NamedThing abolished protein localization to kinetochore during meiotic anaphase I A cell phenotype in which the localization of a protein to the kinetochore of a chromosome does not occur during anaphase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007688 biolink:NamedThing abolished protein localization to kinetochore during meiotic metaphase I A cell phenotype in which the localization of a protein to the kinetochore of a chromosome does not occur during metaphase of the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007704 biolink:NamedThing decreased protein localization to lateral cell cortex during glucose starvation A cell phenotype in which the localization of a protein to the cell cortex is decreased when the cell is subject to glucose starvation. FYPO_relaxed.owl FYPO:0007719 biolink:NamedThing abolished SMN complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which SMN complex assembly is abolished. FYPO_relaxed.owl FYPO:0007720 biolink:NamedThing decreased SMN complex assembly A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of SMN complex assembly is decreased. FYPO_relaxed.owl FYPO:0007732 biolink:NamedThing normal protein localization to chromatin at 3' end of RNA polymerase III-transcribed genes during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin at the 3' ends of genes that can be transcribed by RNA polymerase III is normal (i.e. indistinguishable from wild type) during metaphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007738 biolink:NamedThing normal protein localization to chromatin at 3' end of RNA polymerase II-transcribed genes during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin at the 3' ends of genes that can be transcribed by RNA polymerase II is normal (i.e. indistinguishable from wild type) during metaphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007741 biolink:NamedThing abnormal protein distribution along RNA polymerase II-transcribed genes during mitotic metaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is abnormal during metaphase of the mitotic cell cycle. FYPO_relaxed.owl FYPO:0007834 biolink:NamedThing protein displaced from 5' end to 3' end of RNA polymerase II-transcribed genes A cell phenotype observed in the vegetative growth phase of the life cycle in which the distribution of a protein localized to chromatin along the length of genes that can be transcribed by RNA polymerase II is altered such that more of the protein is present at the 3' end, and less at the 5' end, than normal. FYPO_relaxed.owl FYPO:0007742 biolink:NamedThing premature actomyosin contractile ring assembly during mitotic interphase A cellular process phenotype observed in the vegetative growth phase of the life cycle in which actomyosin contractile ring assembly begins during interphase of the mitotic cell cycle. Contractile ring assembly normally begins during M phase. FYPO_relaxed.owl FYPO:0007744 biolink:NamedThing spindle collapse during meiotic prophase I A cell phenotype in which a short spindle assembles during the first meiotic nuclear division, and may begin elongation, but does not elongate normally or completely, and collapses during prophase I. Upon collapse the spindle may break or shrink. FYPO_relaxed.owl FYPO:0007751 biolink:NamedThing spindle collapse during meiotic prometaphase I A cell phenotype in which a short spindle assembles during the first meiotic nuclear division, and may begin elongation, but does not elongate normally or completely, and collapses during prometaphase I. Upon collapse the spindle may break or shrink. FYPO_relaxed.owl FYPO:0007746 biolink:NamedThing normal spindle elongation during meiotic metaphase I A cellular process phenotype in which the spindle elongates during metaphase of the first meiotic nuclear division, when elongation is normally paused. FYPO_relaxed.owl FYPO:0007748 biolink:NamedThing increased duration of spindle assembly during meiosis I A cellular process phenotype in which the duration of spindle assembly during meiosis I is longer than normal. The total duration of spindle phases I (initial assembly and first stage of elongation) and II (in which elongation normally pauses, and which coincides with metaphase I) is increased due to prolongation of either or both phases. FYPO_relaxed.owl FYPO:0007849 biolink:NamedThing spindle self-assembly during meiosis I A cellular process phenotype in which microtubules self-assemble into a spindle without the participation of the spindle pole body (SPB) during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007750 biolink:NamedThing normal protein localization to meiotic spindle during meiosis I A cellular process phenotype in which the localization of a protein to the spindle is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007867 biolink:NamedThing normal protein localization to meiotic spindle pole during meiosis I A cell phenotype in which the localization of a protein to one or both poles of the meiotic spindle is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division. FYPO_relaxed.owl FYPO:0007754 biolink:NamedThing abolished mitotic spindle formation phase II A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which phase II of mitotic spindle assembly does not occur. During phase II, the spindle is normally maintained at a constant length during mitotic metaphase. FYPO_relaxed.owl FYPO:0007755 biolink:NamedThing short meiotic spindle during metaphase I A physical cellular phenotype in which the spindle is shorter than normal during metaphase of meiosis I. FYPO_relaxed.owl FYPO:0007846 biolink:NamedThing short meiotic spindle during anaphase I A physical cellular phenotype in which the spindle is shorter than normal during anaphase of meiosis I. FYPO_relaxed.owl FYPO:0007757 biolink:NamedThing normal protein localization to new mitotic spindle pole body during anaphase A cell phenotype observed in the vegetative growth phase of the life cycle in which the localization of a protein to the new mitotic spindle pole body is normal (i.e. indistinguishable from wild type) during anaphase. FYPO_relaxed.owl FYPO:0007764 biolink:NamedThing enlarged lipid droplets surrounded by endoplasmic reticulum A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which lipid droplets are larger than normal, and are surrounded by endoplasmic reticulum. Fewer droplets than normal may be present. FYPO_relaxed.owl FYPO:0007766 biolink:NamedThing abolished protein level oscillation during mitotic cell cycle A gene expression phenotype in which protein levels that normally vary over the course of the mitotic cell cycle do not vary. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007774 biolink:NamedThing increased invasive hyphal growth A phenotype in which fission yeast forms hyphae that invade the growth medium to a greater extent than normal. Invasively growing cells are wash-resistant when cultured in agar solid medium for several days. FYPO_relaxed.owl FYPO:0007775 biolink:NamedThing increased hyphal length A phenotype in which hyphae are longer than normal. FYPO_relaxed.owl FYPO:0007776 biolink:NamedThing decreased hyphal length A phenotype in which hyphae are shorter than normal. FYPO_relaxed.owl FYPO:0007777 biolink:NamedThing increased hyphal branching A phenotype in which hyphae form more branched filaments than normal. FYPO_relaxed.owl FYPO:0007778 biolink:NamedThing decreased hyphal branching A phenotype in which hyphae form fewer branched filaments than normal. FYPO_relaxed.owl FYPO:0007779 biolink:NamedThing increased mycelial expansion A phenotype in which the mycelium formed by fission yeast undergoing hyphal growth covers a larger area than normal. FYPO_relaxed.owl FYPO:0007780 biolink:NamedThing decreased mycelial expansion A phenotype in which the mycelium formed by fission yeast undergoing hyphal growth covers a smaller area than normal. FYPO_relaxed.owl FYPO:0007781 biolink:NamedThing delayed onset of hyphal transition A phenotype in which the transition from yeast-form to hyphal growth begins later than normal. FYPO_relaxed.owl FYPO:0007782 biolink:NamedThing abolished hyphal transition A phenotype in which the transition from yeast-form to hyphal growth does not occur under conditions that normally induce it. FYPO_relaxed.owl FYPO:0007788 biolink:NamedThing increased macroautophagy during vegetative growth A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the occurrence of macroautophagy is increased. FYPO_relaxed.owl FYPO:0007824 biolink:NamedThing decreased quorum sensing response A biological process phenotype in which a response to quorum sensing molecules (QSMs) is decreased. The amount of QSMs may be normal. FYPO_relaxed.owl FYPO:0007826 biolink:NamedThing decreased protein level during cellular response to leucine starvation A cell phenotype observed in the vegetative growth phase of the life cycle in which the amount of protein measured in a cell during a cellular response to leucine starvation is lower than normal. Total protein or a specific protein may be affected. FYPO_relaxed.owl FYPO:0007836 biolink:NamedThing increased nucleosome occupancy at subtelomere A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is greater than normal at subtelomeric regions. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0007837 biolink:NamedThing decreased nucleosome occupancy at subtelomere A cellular process phenotype observed in the vegetative growth phase of the life cycle in which nucleosome occupancy is lower than normal at subtelomeric regions. Nucleosome occupancy measures the tendency for DNA in a given region to be packaged into nucleosomes. FYPO_relaxed.owl FYPO:0007852 biolink:NamedThing normal meiotic spindle polarity A physical cellular phenotype in which spindle microtubules are oriented normally, i.e. with minus ends at the spindle poles and plus ends at the midzone, during or both meiotic nuclear divisions. FYPO_relaxed.owl FYPO:0007857 biolink:NamedThing normal protein localization to meiotic spindle midzone during meiosis I A cellular process phenotype in which the localization of a protein to the spindle midzone is normal (i.e. indistinguishable from wild type) during the first meiotic nuclear division. The meiotic spindle midzone is the area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap. FYPO_relaxed.owl FYPO:0007883 biolink:NamedThing decreased cleavage-dependent termination of RNA polymerase II transcription A cellular process phenotype observed in the vegetative growth phase of the life cycle in which cleavage-dependent termination of transcription by RNA polymerase II is abnormal. In cleavage-dependent termination, co-transcriptional secondary structure-dependent endonucleolytic cleavage triggers RNA polymerase II transcription termination; transcripts are not polyadenylated, and are subsequently rapidly degraded in the nucleus. Termination of all transcripts, or a subset of transcripts, may be affected. FYPO_relaxed.owl FYPO:0007897 biolink:NamedThing increased protein phosphorylation during mitotic exit A cellular process during mitosis in which the phosphorylation of one or more specific proteins, or of specific protein sites, occurs to a greater extent than normal during mitotic exit. FYPO_relaxed.owl FYPO:0007937 biolink:NamedThing increased number of DNA breakpoint junctions during stationary phase A cell phenotype in which the number of sites of DNA breakpoint junctions is greater than normal during stationary phase. FYPO_relaxed.owl FYPO:0007939 biolink:NamedThing normal chromatin loop formation during meiotic prophase I A cellular process phenotype in which any chromatin loop formation is normal (i.e. indistinguishable from wild type) during the meiotic prophase I. FYPO_relaxed.owl FYPO:0007942 biolink:NamedThing increased length of chromatin loops during meiotic prophase I A cellular process phenotype in which chromatin loop formation during meiotic prophase I results in chromatin loops of increased length. FYPO_relaxed.owl FYPO:0007950 biolink:NamedThing increased mating efficency during nitrogen stress A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is higher than normal when a cell is subject to nitrogen stress. FYPO_relaxed.owl FYPO:0007951 biolink:NamedThing increased mating effciency during nitrogen starvation A biological process phenotype in which the observed mating efficiency, as determined by counting zygotes, asci, and sometimes spores, is higher than normal when a cell is subject to nitrogen starvation. FYPO_relaxed.owl FYPO:0007965 biolink:NamedThing increased spontaneous diploidization due to abolished sister chromatid separation A cell phenotype observed in the vegetative growth phase of the life cycle in which heterothallic haploid cells spontaneously form cells with diploid DNA content after failing chromosome segregation and consequently nuclear division. The nucleus is displaced from the cell center by actin cables, preventing chromosome cut and leading to diploidisation. FYPO_relaxed.owl FYPO:0007968 biolink:NamedThing cut with mitotic spindle microtubules protruding beyond spindle pole body An inviable phenotype observed in the vegetative growth phase of the life cycle after normal chromosome separation in which pushing forces exerted by microtubules protruding from the spindle pole bodies displace one of the daughter nuclei to the site of cytokinesis. The septum then physically divides that nucleus into two parts, giving rise to inviable daughter cell. FYPO_relaxed.owl FYPO:0007969 biolink:NamedThing short-lived long mitotic spindle microtubules protruding beyond spindle pole body A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which cells form mitotic spindle microtubules that are longer than normal, extend beyond the spindle pole body and are present transiently. The protruding spindle microtubules are surrounded by an extension of the nuclear envelope. FYPO_relaxed.owl FYPO:0007972 biolink:NamedThing decreased rate of interpolar microtubule polymerization during mitotic anaphase B A microtubule cytoskeleton organization phenotype observed during mitotic anaphase B in which interpolar microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule occurs at a lower rate, or speed, than normal. FYPO_relaxed.owl FYPO:0009000 biolink:NamedThing decreased rate of cytoplasmic microtubule polymerization during mitotic interphase A microtubule cytoskeleton organization phenotype observed during mitotic interphase in which cytoplasmic microtubule polymerization, i.e. the addition of tubulin dimers to the plus end of a microtubule occurs at a lower rate, or speed, than normal. FYPO_relaxed.owl FYPO:0007974 biolink:NamedThing increased rate of interpolar microtubule polymerization inside the mitotic nuclear membrane bridge A microtubule cytoskeleton organization phenotype observed during mitotic anaphase B in which interpolar microtubule polymerization occurs at a higher rate, or speed, than normal for microtubules with their plus ends inside the nuclear membrane bridge formed during mitotic anaphase B. FYPO_relaxed.owl FYPO:0007975 biolink:NamedThing abnormal distribution of interpolar microtubule rescue during anaphase B A cellular process phenotype observed during anaphase B in which the distribution of the positions of interpolar microtubule rescues is abnormal. The positions of interpolar microtubule rescues are where the transitions from shrinkage to growth occur. FYPO_relaxed.owl FYPO:0007976 biolink:NamedThing increased duration of interpolar microtubule growth events during anaphase B A microtubule cytoskeleton organization phenotype observed during anaphase B in which the duration of interpolar microtubule growth events is longer. FYPO_relaxed.owl FYPO:0008008 biolink:NamedThing increased duration of cytoplasmic microtubule growth events during mitotic interphase A microtubule cytoskeleton organization phenotype observed during mitotic interphase in which the duration of cytoplasmic microtubule growth events is longer. FYPO_relaxed.owl FYPO:0009001 biolink:NamedThing decreased duration of cytoplasmic microtubule growth events during mitotic interphase A microtubule cytoskeleton organization phenotype observed during mitotic interphase in which the duration of cytoplasmic microtubule growth events is shorter. FYPO_relaxed.owl FYPO:0007978 biolink:NamedThing decreased homologous chromosome pairing during meiosis I prophase A cellular process phenotype in which homologous chromosome pairing during meiosis (synapsis) is decreased during meiotic prophase I. FYPO_relaxed.owl FYPO:0007982 biolink:NamedThing single microtubule bundle with aster-like microtubules A physical cellular phenotype observed in the vegetative growth phase of the life cycle in which all detectable microtubules are present in a single bundle and are not normally crosslinked, resulting in an aster-like organisation. See PMID:15068790. FYPO_relaxed.owl FYPO:0007986 biolink:NamedThing decreased protein localization to interphase microtubule bundle overlap A cell phenotype observed during mitotic interphase in which the localization of a protein to the microtubule overlap of cytoplasmic microtubule bundles is decreased. FYPO_relaxed.owl FYPO:0007989 biolink:NamedThing abolished nuclear congression during mating A cellular process phenotype in which karyogamy involved in conjugation with cellular fusion does not occur because the nuclei fail to come in physical contact. FYPO_relaxed.owl FYPO:0008007 biolink:NamedThing mitotic spindle collapse during anaphase B elongation with progressive spindle pole congression A cell phenotype in which a mitotic spindle assembles and begins to elongate, but collapses during anaphase B, with the collapse being followed by the spindle poles congressing together. In some cases, this is known to be driven by depolymerisation of microtubules part of a merotelic attachment (PMID:19948483). FYPO_relaxed.owl FYPO:0008011 biolink:NamedThing abolished siRNA loading onto RITS complex An RNA localization phenotype where the loading of siRNAs onto the RITs complex is abolished. FYPO_relaxed.owl FYPO:0008014 biolink:NamedThing decreased protein localization to CENP-A containing chromatin during mitosis A cell phenotype observed during mitotic M phase in which the localization of a protein to CENP-A containing chromatin is decreased. FYPO_relaxed.owl FYPO:0008025 biolink:NamedThing normal protein localization to CENP-A containing chromatin during mitosis A cell phenotype observed during mitotic M-phase in which the localization of a protein to the CENP-A containing chromatin is normal (i.e. indistinguishable from wild type). FYPO_relaxed.owl FYPO:0008026 biolink:NamedThing increased protein localization to CENP-A containing chromatin during mitosis A cell phenotype observed during mitotic M-phase in which the localization of a protein to CENP-A containing chromatin is increased. FYPO_relaxed.owl FYPO:0008035 biolink:NamedThing ectopic CENP-A containing chromatin assembly at pericentromeric heterochromatin A cellular process phenotype observed in the vegetative growth phase of the life cycle in which chromatin containing the histone H3 variant CenH3 (also called CENP-A; Cnp1 in S. pombe) are assembled in the pericentromeric heterochromatin. CENP-A-containing nucleosomes are normally assembled into chromatin at the centromeres, encompassing the central core and centromeric inner repeat regions. FYPO_relaxed.owl FYPO:0008037 biolink:NamedThing decreased rate of transcription elongation from RNA polymerase II promoter A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the rate of elongation of a transcript initiated from an RNA polymerase II promoter is abnormal. FYPO_relaxed.owl FYPO:0008038 biolink:NamedThing abolished histone H3-K4 trimethylation during mitosis A cellular process phenotype observed in mitosis in which trimethylation of lysine at position 4 of histone H3 does not occur. FYPO_relaxed.owl